CN204147036U - Woundless blood sugar Analytical system - Google Patents

Woundless blood sugar Analytical system Download PDF

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Publication number
CN204147036U
CN204147036U CN201420508757.7U CN201420508757U CN204147036U CN 204147036 U CN204147036 U CN 204147036U CN 201420508757 U CN201420508757 U CN 201420508757U CN 204147036 U CN204147036 U CN 204147036U
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China
Prior art keywords
module
infrared light
circuit
signal
blood sugar
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Expired - Fee Related
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CN201420508757.7U
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Chinese (zh)
Inventor
张贯京
陈兴明
葛新科
王海荣
刘国勇
张少鹏
樊智辉
方静芳
徐之艳
周亮
程金兢
徐菊红
蒋兴菊
杨青蓝
刘义
肖应芬
何晓霞
吴彬霞
郑慧华
唐小浪
张世导
李潇云
侯云超
赵学明
赵雪竹
梁艳妮
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Shenzhen Qianhai AnyCheck Information Technology Co Ltd
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Shenzhen Qianhai AnyCheck Information Technology Co Ltd
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Abstract

The utility model discloses a kind of Woundless blood sugar Analytical system, comprise the infrared light emission module for real time emission preset wavelength; For the infrared signal of real-time reception one wavelength range, and the infrared signal of reception is converted to the infrared light receiver module of analog electrical signal; For converting described analog electrical signal to digital signal; For described digital signal is carried out analytical calculation, finally obtain the data processing module of the measurement result of human blood glucose concentration; For inputting instruction, and show the human-computer interaction module of the measurement result of described human blood glucose concentration or the measurement result by this human blood glucose concentration of voice broadcast.This utility model Woundless blood sugar Analytical system eliminates the interference of water and the interference of human body self when measuring human blood glucose concentration, more accurately repeatability that is credible, measurement result is better, highly sensitive to make measurement result, and for specific testing human, this system has good measurement result specificity.

Description

Woundless blood sugar Analytical system
Technical field
This utility model relates to medical instruments field, particularly relates to a kind of Woundless blood sugar Analytical system.
Background technology
Diabetics, in order to avoid the complication of diabetes, needs measure continually and control blood sugar concentration, and at present in China, the method major part that diabetics measures blood sugar concentration adopts the blood-glucose meter having wound.The measurement that blood glucose concentration is carried out in blood sampling frequently on the one hand brings huge financial burden and medical expense to diabetics, on the other hand also to the risk that diabetics brings huge health and mental anguish and catches.In order to tackle above-mentioned situation, in the urgent need to a kind of Fast measurement system of the non-invasive blood glucose concentration for diabetics.
At present, utilize noinvasive infrared light to measure blood glucose and have relevant report, but the technology utilizing infrared light to measure human blood glucose concentration also has many imperfection parts.On the one hand, the characteristic light of blood glucose is difficult to determine, does not up to the present also search out a preferably characteristic light; Two aspects, the absworption peak of water and glucose has overlap, and the interference of water is difficult to reject; Three aspects, although glucose has very strong absorbance to its characteristic light, other tissue of human body also has the strong absorption property received to the characteristic light of glucose, and e.g., the characteristic light of glucose just can not penetrate human skeleton; Four aspects, very large difference is there is in the same body part of different people to the absorbance of the characteristic light of glucose, this difference is mainly because there is larger difference, so the blood glucose measurement wanting to utilize a mathematical model to carry out all groups is unpractical in the bodily tissue of tester, the composition of cell and composition or size.
Utility model content
Main purpose of the present utility model is to solve the problem that the estimating precision of existing non-invasive blood sugar instrument to blood glucose is poor, sensitivity is low.
For achieving the above object, the Woundless blood sugar system that this utility model provides, comprises with lower module:
Infrared light emission module, for the infrared light of real time emission preset wavelength;
Infrared light receiver module, for the infrared signal of real-time reception one wavelength range, and converts the infrared signal of reception to analog electrical signal;
Signal conversion module, described signal conversion module connects described infrared light receiver module, and this signal conversion module converts this analog electrical signal described to digital signal;
Data processing module, described data processing module connects described signal conversion module, and described digital signal is carried out analytical calculation by this data processing module, finally obtains the measurement result of measured human blood glucose concentration;
Human-computer interaction module, described human-computer interaction module connects described data processing module, and described human-computer interaction module for inputting instruction, and shows the measurement result of described human blood glucose concentration or the measurement result by this human blood glucose concentration of voice broadcast.
Preferably, this Woundless blood sugar Analytical system also comprises data communication module, data processing module described in described data communication model calling, and this data communication module is used for the measurement result of described human blood glucose concentration to carry out remote data transmission.
Preferably, described infrared light emission module comprises the infrared light emission pipe of at least three different wave lengths.
Preferably, the drive singal of described infrared light emission module is pulse signal, and the scope of the dutycycle of this pulse signal is 1:20 to 1:1.5.
Preferably, described Woundless blood sugar Analytical system also comprises for driving described infrared light emission module and infrared light receiver module driving power, and the ripple of described driving power is less than 100mv.
Preferably, the input end signal voltage difference of described signal conversion module is less than 50mv.
Preferably, the signal switching rate of described signal conversion module is 10HZ to 1000HZ.
Preferably, described infrared light emission module comprises infrared light emission circuit and power circuit; Described infrared light receiver module comprises infrared light receiving circuit and power circuit; Described signal conversion module comprises filter circuit, signal amplification circuit, signal selecting circuit and signaling conversion circuit; Described data processor module comprises microcontroller circuit and power circuit; Described human-computer interaction module comprises microcontroller circuit, input circuit and display circuit, and described data communication module comprises microcontroller circuit and data communication circuit.
This utility model Woundless blood sugar Analytical system eliminates the interference of water and the interference of human body self when measuring human blood glucose concentration, more accurately repeatability that is credible, measurement result is better, highly sensitive to make measurement result, and for specific testing human, this system has good measurement result specificity.
Accompanying drawing explanation
Fig. 1 is be the hardware block diagram of this utility model Woundless blood sugar Analytical system one embodiment;
Fig. 2 is the hardware block diagram of another embodiment of this utility model Woundless blood sugar Analytical system;
Fig. 3 is the circuit diagram of the power supply of this utility model Woundless blood sugar Analytical system;
Fig. 4 is the circuit diagram of communication module and relevant supplementary module in this utility model Woundless blood sugar Analytical system;
Fig. 5 is the interface circuit figure of microprocessor in this utility model Woundless blood sugar Analytical system;
Fig. 6 is the interface circuit figure of the LCM module of 128X64 in this utility model Woundless blood sugar Analytical system;
Fig. 7 is microcontroller circuit figure in this utility model Woundless blood sugar Analytical system;
Fig. 8 is thumper drive circuit figure and signal input circuit figure in this utility model Woundless blood sugar Analytical system;
Fig. 9 is this utility model Woundless blood sugar Analytical system mid-infrared light receiving circuit and signaling conversion circuit figure;
Figure 10 is that this utility model Woundless blood sugar Analytical system mid-infrared light launches drive circuit figure.
The realization of this utility model object, functional characteristics and advantage will in conjunction with the embodiments, are described further with reference to accompanying drawing.
Detailed description of the invention
Should be appreciated that specific embodiment described herein only in order to explain this utility model, and be not used in restriction this utility model.
This utility model provides a kind of Woundless blood sugar Analytical system with reference to Fig. 1, and this system comprises with lower module
Infrared light emission mould 10, for the infrared light of real time emission preset wavelength;
Infrared light receiver module 11, for the infrared signal of real-time reception one wavelength range, and converts the infrared signal of reception to analog electrical signal;
Signal conversion module 12, described signal conversion module 12 connects described infrared light receiver module 11, and this signal conversion module converts this analog electrical signal described to digital signal;
Data processing module 13, described data processing module 13 connects described signal conversion module 12, and described digital signal is carried out analytical calculation by this data processing module 13, finally obtains the measurement result of measured human blood glucose concentration;
Human-computer interaction module 14, described human-computer interaction module 14 connects described data processing module 13, described human-computer interaction module 14 for receiving the instruction of user's input, and shows the measurement result of described human blood glucose concentration or the measurement result by this human blood glucose concentration of voice broadcast.
Concrete, the infrared light of transmitting one specific wavelength that infrared light emission module 10 is real-time, the Infrared irradiation of this specific wavelength is at the predetermined patterns of person's health to be measured, such as ear-lobe, in one's ear, neck arteries position, wrist artery position, palm thumb web or naris position, the infrared light of specific wavelength (as 1650nm) is after the predetermined patterns of gauger, there is decay to a certain degree, after infrared light receiver module receives the infrared signal of this decay, convert this signal to analog electrical signal, it is (concrete that the size of this analog electrical signal and human blood glucose concentration present certain mathematical model relation, in mensuration process, the mensuration of water to glucose has interference, namely the infrared light of water to the characteristic wavelength of glucose also has absorption, so just need to measure water to the absorbtivity of the infrared light of the characteristic wavelength of glucose at this, then remove in the amount of raw glucose to the part glucose characteristic light that water absorbs by the basis of the absorbtivity of its characteristic light, to obtain the absolute total amount that glucose absorbs its characteristic light).After the infrared signal of decaying converts analog electrical signal to, signal conversion module 12 will reflect that the analog electrical signal of blood sugar for human body concentration of glucose converts thereof into microprocessor module acceptable digital signal after carrying out filtering, amplification; After data processor module 13 receives this digital signal, this digital signal analyzed and calculates, then obtaining measured human blood glucose concentration.Last microprocessor module by human-computer interaction module measure result display or pass through voice broadcast.
Further, with reference to Fig. 2, this Woundless blood sugar Analytical system also comprises data communication module 15, and described data communication module 15 connects described data processing module 13, and this data communication module 15 is for carrying out remote data transmission by the measurement result of described human blood glucose concentration.
Concrete, this Woundless blood sugar Analytical system is not limited to its measurement result and is shown by display module or pass through voice broadcast, the all right setting data communication module of this system, remote information communication function can be realized, the measurement result of native system can be carried out the Informatization Service functions such as remote data transmission.
System will carry out system initialization after starting startup, comprise and read the initial infrared Absorption rate of initial blood glucose concentration value and blood sugar for human body constant value from memorizer, comprise and initialize some parameters and data (at the beginning of data acquisition, need the blood sugar measuring method carrying out using Wicresoft, obtain this particular measurement personnel blood glucose value, this blood glucose value can manually be input in native system product, carries out infrared light method to blood glucose measurement simultaneously, obtains code value in infrared light blood glucose).After initialization completes, namely system carries out detecting accessing with or without detection signal, both the measurement whether having tester to carry out blood glucose had been checked, input if any detection signal, just some process carried out to this signal and analyze, as carried out the process of the digital filtering such as debounce, deburring to signal data, some dynamic data analysis and judgements are carried out with to data, judge trend and the trend of data, until this measurement data reads these stable data after tending towards stability, again these data are carried out calculated with mathematical model, thus calculate the concentration measurement of the blood-glucose of person to be measured; Finally the measurement result obtained is exported.
Further, described infrared light emission module comprises the infrared light emission pipe of at least three different wave lengths.
Concrete, due to native system carry out measuring content of blood sugar time, first the characteristic spectrum (such as 1650nm) of a glucose is needed, with the absorbtivity of Preliminary Determination glucose to its characteristic light, in order to make glucose more accurate to the absorbtivity of its characteristic light, also need to discharge water mitigation in this mensuration process.In mensuration process, the mensuration of water to glucose has interference, namely the infrared light of water to the characteristic wavelength of glucose also has absorption, so just need to measure water to the absorbtivity of the infrared light of the characteristic wavelength of glucose at this, then remove in the amount of raw glucose to the part glucose characteristic light that water absorbs by the basis of the absorbtivity of its characteristic light, to obtain the absolute total amount that glucose absorbs its characteristic light.Concrete, the infrared Absorption of glucose to 1400nm is less, and the infrared light of water to this wavelength has stronger absorption, so the absorbtivity (such as 1650nm) of water to the characteristic light of glucose can be substituted by measuring the absorbtivity of water to the infrared light of 1400nm, reject with this interference that water measures glucose content.In addition, because native system is in the application of reality is measured, need the measurement point location position carrying out the measured in advance, during to ensure to measure at every turn, the irradiation of infrared light is at the same specific part of gauger's health.First, by choosing the infrared light of 1200nm, (infrared light of this 1200nm can penetrate skeleton, and the absorbance of infrared light is with the thickness direct proportionality of tissue) irradiate near body measurements 2 positions after, the absorbance of infrared light is measured, obtain these 2 infrared lights and measure interior code value, this interior code value is stored.Both code value in the infrared light measured value of 1200nm and demarcation is compared when measuring process starts, on duty more than 3% time, both these 2 infrared lights were not be radiated at (compared with timing signal) on same position, just need constantly to move irradiation or measuring position, until location, measuring position carries out the measurement of this utility model Woundless blood sugar again after meeting the requirements.
In said process, at least need the infrared light of three different wavelength, therefore infrared light emission module comprises the infrared light emission pipe of at least three different wave lengths.
Further, the drive singal of described infrared light emission module 10 is pulse signals, and the scope of the dutycycle of this pulse signal is 1:20 to 1:1.5.
Concrete, in order to solve the fluctuation problem of infrared emission light light intensity and increase the penetration capacity of infrared light, the dutycycle of impulse wave is from 1:1.5 to 1:20, so just preferably resolves the problem that infrared light drives fluctuation.When dutycycle is less than 1:20 time, light intensity and the luminous flux of institute's emission characteristic light are too little, penetrate poor effect, do not reach measurement requirement; When dutycycle is greater than 1:1.5, there is larger fluctuation in the light intensity of institute's emission characteristic light and luminous flux, and the error of measurement result is comparatively large, does not also reach and measures needs.
Further, described Woundless blood sugar Analytical system also comprises for driving described infrared light emission module and infrared light receiver module driving power, and the ripple of described driving power is less than 100mv.
Concrete, due under identical power drives, the infrared light that infrared light emission pipe is launched is not identical, and it always has fluctuation, and this can cause larger error to measurement.In the present embodiment in order to reduce this error, described infrared light emission module 10 is identical with the driving power of infrared light receiver module 11, when the ripple of this supply voltage is less, the light flux variations rate of infrared light can be made to reduce, the fluctuation of the infrared light that infrared light emission pipe is launched is also less, concrete, the ripple of this power supply is less than 100mv.
Further, the input end signal of described signal conversion module is less than 50mv.
Concrete, the output signal of sensor belongs to small-signal, and generally at below 10mv, signal input part voltage difference is less than 50mv, because the amplification of amplifier to 100 times, can exceed this voltage and can cause the scope of the output voltage of amplifier and the inefficacy of amplifier.
Further, the signal switching rate of described signal conversion module is 10HZ to 1000HZ.
Concrete, the reason of selection 10HZ to 1000HZ is: if be less than 10HZ, then the speed of data sampling and analysis is too slow, can not realize the object measured in real time preferably; If be greater than 1000HZ simultaneously, sampling rate is too fast, and many data can be caused not carry out analysis will be abandoned, simultaneously too high sampling rate, also can cause the data instability of sampling.
Further, described infrared light emission module 10 comprises infrared light emission circuit and power circuit; Described infrared light receiver module 11 comprises infrared light receiving circuit and power circuit; Described signal conversion module 12 comprises filter circuit, signal amplification circuit, signal selecting circuit and signaling conversion circuit; Described data processor module 13 comprises microcontroller circuit and power circuit; Described human-computer interaction module 14 comprises microcontroller circuit, input circuit and display circuit, and described data communication module 15 comprises microcontroller circuit and data communication circuit.
Concrete, this system comprises multichannel infrared light emission circuit, power circuit, infrared light receiving circuit, filter circuit, signal amplification circuit, signal selecting circuit, signaling conversion circuit, input circuit, display circuit, data communication circuit and microcontroller circuit, described multichannel infrared light emission circuit, power circuit, infrared light receiving circuit, filter circuit, signal amplification circuit, signal selecting circuit, signaling conversion circuit, input circuit, display circuit, data communication circuit and microcontroller circuit are electrically connected successively, microcontroller circuit respectively with input circuit, display circuit and the electrical connection of data communication circuit, infrared light emission circuit and power circuit form infrared light emission module, and infrared light receiving circuit and power circuit form infrared light receiver module, filter circuit, low level signal amplification, signal selecting circuit, signaling conversion circuit formation signal conversion module, microcontroller circuit and power circuit composition data processor module, microcontroller circuit, input through keyboard circuit and display circuit and form human-computer interaction module.
Introduce circuit hardware and operation principle below in conjunction with accompanying drawing, be power pack with reference to Fig. 3, POWER, it is made up of 2 grades of DC-DC circuit and corresponding filter circuit thereof respectively.
Reference Fig. 4, MAX232 are data communication module and auxiliary circuit, and it forms communicating circuit by communication chip and corresponding electric capacity, and USART RX and USART TX is the interface with microprocessor.
With reference to the interface circuit that Fig. 5, I/O circuit is the I/O of microprocessor.
With reference to the interface circuit that Fig. 6, LCD circuit is the LCM module of common 128X64.
With reference to Fig. 7, MCU is microprocessor module, this 8RF3421 microprocessor is 8-bit microprocessor, it is the microprocessor of flash ROM structure, its instruction system has 43 instructions, and there is the communication structure of 1 road UART inside, the crystal oscillating circuit of interior band 16MHZ, running voltage 2.3V to 5.5V, it has 3 kinds of mode of operations.
With reference to Fig. 8, BUZZER is thumper drive circuit, it is driven by the audion of 8050, and KEY is signal input circuit (also claiming key circuit), and the object connecing 4.7k ohmage is the impact instantaneous large-current to I/O mouth when eliminating key jitter.
With reference to Fig. 9, SENSOR_A is infrared light receiving circuit and signaling conversion circuit, it receives the infrared light of signal intensity attenuation after human body specific part by D1-infrared receiving tube, then current signal is converted to, current signal is through resistance R6, signal after R12 on R6 is both as sampled signal, this sampled signal is via R4, R9, C11, signal conversion module is entered after the filter circuit of C12 and C15 composition--CS1, this signal conversion module inside is contained: operation amplifier, multi-path choice, analog digital conversion (ADC) circuit, this analog digital conversion (ADC) module is the ADC module of 24, it has programmable operational amplification circuit and multiplexer circuit, MCU microprocessor is outputted to through SCLK and DOUT interface after signal conversion, this signal carries out Filtering Processing through MCU, signal condition is analyzed and calculated with mathematical model, finally by MCU, measurement result is exported.
Reference Figure 10, SENSOR_B, SENSOR_C, SENSOR_D SENSOR_E, SENSOR_F are 5 infrared light emission drive circuits, and it drives respectively by the audion of a S8050.
These are only preferred embodiment of the present utility model; not thereby the scope of the claims of the present utility model is limited; every utilize this utility model description and accompanying drawing content to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present utility model.

Claims (8)

1. a Woundless blood sugar Analytical system, is characterized in that, comprises with lower module:
Infrared light emission module, for the infrared light of real time emission preset wavelength;
Infrared light receiver module, for the infrared signal of real-time reception one wavelength range, and converts the infrared signal of reception to analog electrical signal;
Signal conversion module, described signal conversion module connects described infrared light receiver module, and this signal conversion module converts this analog electrical signal described to digital signal;
Data processing module, described data processing module connects described signal conversion module, and described digital signal is carried out analytical calculation by this data processing module, finally obtains the measurement result of measured human blood glucose concentration;
Human-computer interaction module, described human-computer interaction module connects described data processing module, and described human-computer interaction module for inputting instruction, and shows the measurement result of described human blood glucose concentration or the measurement result by this human blood glucose concentration of voice broadcast.
2. Woundless blood sugar Analytical system as claimed in claim 1, it is characterized in that, this Woundless blood sugar Analytical system also comprises data communication module, data processing module described in described data communication model calling, this data communication module is used for the measurement result of described human blood glucose concentration to carry out remote data transmission.
3. Woundless blood sugar Analytical system as claimed in claim 1, it is characterized in that, described infrared light emission module comprises the infrared light emission pipe of at least three different wave lengths.
4. the Woundless blood sugar Analytical system as described in claim 1,2 or 3, is characterized in that, the drive singal of described infrared light emission module is pulse signal, and the scope of the dutycycle of this pulse signal is 1:20 to 1:1.5.
5. the Woundless blood sugar Analytical system as described in claim 1,2 or 3, is characterized in that, described Woundless blood sugar Analytical system also comprises for driving described infrared light emission module and infrared light receiver module driving power, and the ripple of described driving power is less than 100mv.
6. the Woundless blood sugar Analytical system as described in claim 1,2 or 3, is characterized in that, the input end signal voltage difference of described signal conversion module is less than 50mv.
7. the Woundless blood sugar Analytical system as described in claim 1,2 or 3, is characterized in that, the signal switching rate of described signal conversion module is 10HZ to 1000HZ.
8. Woundless blood sugar Analytical system as claimed in claim 2, it is characterized in that, described infrared light emission module comprises infrared light emission circuit and power circuit; Described infrared light receiver module comprises infrared light receiving circuit and power circuit; Described signal conversion module comprises filter circuit, signal amplification circuit, signal selecting circuit and signaling conversion circuit; Described data processor module comprises microcontroller circuit and power circuit; Described human-computer interaction module comprises microcontroller circuit, input circuit and display circuit, and described data communication module comprises microcontroller circuit and data communication circuit.
CN201420508757.7U 2014-09-04 2014-09-04 Woundless blood sugar Analytical system Expired - Fee Related CN204147036U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104257390A (en) * 2014-09-04 2015-01-07 深圳市前海安测信息技术有限公司 Noninvasive blood glucose assay method and system

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104257390A (en) * 2014-09-04 2015-01-07 深圳市前海安测信息技术有限公司 Noninvasive blood glucose assay method and system
WO2016033815A1 (en) * 2014-09-04 2016-03-10 深圳市前海安测信息技术有限公司 Non-invasive blood glucose measurement method and system

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