CN111317766A - Heat-clearing anti-inflammatory Chinese herbal medicine composition for livestock - Google Patents

Heat-clearing anti-inflammatory Chinese herbal medicine composition for livestock Download PDF

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Publication number
CN111317766A
CN111317766A CN202010338595.7A CN202010338595A CN111317766A CN 111317766 A CN111317766 A CN 111317766A CN 202010338595 A CN202010338595 A CN 202010338595A CN 111317766 A CN111317766 A CN 111317766A
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CN
China
Prior art keywords
parts
livestock
heat
chinese herbal
herbal medicine
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Pending
Application number
CN202010338595.7A
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Chinese (zh)
Inventor
张海军
刘海亮
伏圣鑫
孙伟
崔新海
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Jinan Tianju Animal Husbandry Technology Co ltd
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Jinan Tianju Animal Husbandry Technology Co ltd
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Priority to CN202010338595.7A priority Critical patent/CN111317766A/en
Publication of CN111317766A publication Critical patent/CN111317766A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Abstract

The invention discloses the technical field of livestock breeding medicine, and discloses a veterinary heat-clearing anti-inflammatory Chinese herbal medicine composition which is composed of the following components in parts by mass: 20 parts of honeysuckle, 20 parts of isatis root, 15 parts of wild chrysanthemum, 10 parts of common andrographis herb, 10 parts of baical skullcap root, 10 parts of dried rehmannia root, 10 parts of coptis root, 8 parts of weeping forsythia capsule, 5 parts of gentian root, 20 parts of feed leavening agent and 300 parts of corn flour, wherein a sample is crushed one by a traditional Chinese medicine crusher and is sieved by a standard sieve of 80 meshes, the sample is fully mixed by a three-dimensional mixer, drinking water is added until the water content is 50%, the mixture is placed in a fermentation chamber at 25-35 ℃ for fermentation for 72 hours and then is placed to room temperature for standby application, when epidemic prevention treatment of heat clearing and inflammation diminishing is required to be carried out on cultured livestock, 100 parts of feed for normal cultured livestock is mixed with 15 parts of the heat clearing and inflammation diminishing Chinese herbal medicine composition for livestock, and the natural traditional Chinese medicine formula.

Description

Heat-clearing anti-inflammatory Chinese herbal medicine composition for livestock
Technical Field
The invention relates to the field of Chinese herbal medicine prevention and treatment of epidemic diseases in livestock breeding, and particularly relates to a heat-clearing anti-inflammatory Chinese herbal medicine composition for livestock.
Background
At present, with the change of demand type to quality type of animal-derived food, veterinary drug residues in known animal-derived food gradually become a focus of worldwide attention, the problem of veterinary drug residues becomes a main obstacle influencing the development of animal husbandry, green, safe and Chinese herbal medicines without veterinary drug residues are sought, and the development of a veterinary heat-clearing and anti-inflammatory Chinese herbal medicine composition is a problem of current consumer demand.
Disclosure of Invention
The invention aims to overcome the defects of the existing veterinary medicine preparation and provides a safe, green and residue-free veterinary heat-clearing and anti-inflammatory Chinese herbal medicine composition.
In order to achieve the purpose, the invention provides the following technical scheme: the technical scheme is characterized by comprising the following components in parts by mass: 20 parts of honeysuckle, 20 parts of isatis root, 15 parts of wild chrysanthemum, 10 parts of common andrographis herb, 10 parts of baical skullcap root, 10 parts of dried rehmannia root, 10 parts of golden thread, 8 parts of weeping forsythia capsule, 5 parts of Chinese gentian root, 20 parts of feed leavening agent and 300 parts of corn flour, wherein a traditional Chinese medicine grinder is adopted to grind a sample one by one, the sample is sieved by a standard sieve of 80 meshes, then the sample is put into a three-dimensional mixer to be fully mixed, drinking water is added until the water content is 50%, the sample is placed in a fermenting chamber at 25-35 ℃ to be fermented for 72 hours and then is put at room temperature for standby application, when the heat clearing and anti-inflammatory prevention and treatment of the cultivated livestock are required, 100 parts of feed for the normally cultivated livestock are mixed with 15 parts by mass, the feed is uniformly mixed and then supplied for the cultivated livestock to eat, and pharmacological research shows that the honeysuckle and the isati, the honeysuckle, the scutellaria baicalensis and the forsythia have more obvious inhibiting and killing effects on gram-positive and gram-negative pathogenic bacteria, are broad-spectrum antibacterial drugs, have good heat-clearing effects on the wild chrysanthemum and the andrographis paniculata, and are matched with other components and fermentation effects to implement heat-clearing and anti-inflammatory applications for livestock.
The invention has the beneficial effects that: the pure traditional Chinese medicine formula has no toxic or side effect and no veterinary drug residue, is suitable for preventing and treating heat-clearing and anti-inflammatory of the cultured livestock, is the problem to be solved by the current consumer demand, and is beneficial to the healthy and benign development of the livestock breeding industry.
Detailed Description
The technical scheme is characterized by comprising the following components in parts by mass: 20 parts of honeysuckle, 20 parts of isatis root, 15 parts of wild chrysanthemum flower, 10 parts of common andrographis herb, 10 parts of baical skullcap root, 10 parts of dried rehmannia root, 10 parts of coptis root, 8 parts of weeping forsythia capsule, 5 parts of gentian, 20 parts of feed leavening agent and 300 parts of corn flour.
Further comprising: the preparation method of the material with the composition comprises the following steps:
(1) the proportioning materials with the formula larger than 80 meshes are mixed and crushed into powdery particles by a traditional Chinese medicine crusher, and the powdery particles are sieved by a standard sieve with 80 meshes.
(2) Pulverizing into powder particles, sieving with 80 mesh standard sieve, and mixing with three-dimensional mixer to obtain mixture for fermentation.
(3) Making into fermented mixture, adding drinking water until water content is 50%, and fermenting at 25-35 deg.C for 72 hr to room temperature.
Further comprising: when epidemic prevention treatment for clearing heat and resisting inflammation is required to be carried out on the cultured livestock, the material for standby at room temperature is prepared by uniformly mixing 100 parts by mass of feed eaten by the cultured livestock and 15 parts by mass of each Chinese herbal medicine for clearing heat and resisting inflammation for livestock.
Grouping comparison test:
the test takes breeding pigs as an example, a comparison effect test is carried out in a high-temperature season with high incidence of the heat-clearing anti-inflammatory epidemic disease, the breeding pigs are selected for 1 month, food, spirit and feces are observed for 1 week, after no adverse reaction or disease is determined, the breeding pigs are randomly divided into two groups, one group is a test group, the other group is a control group, 100 animals are fed to the control group, the control group is fed with normal basic ration for food intake every day, the test group is fed with 100 parts of normal pig feed for feeding every day, the heat-clearing anti-inflammatory Chinese herbal medicine composition for veterinary use is prepared by uniformly mixing 15 parts by mass and is fed to the pigs for food intake, the test pigs are all fed and managed under the same environment, and the morbidity and the mortality of each.
The data table is as follows:
grouping: in the first month: morbidity/mortality February: morbidity/mortality In the third month: morbidity/mortality
Test group 2/0 deaths in morbidity 1 head of disease/0 head of death 0 head of disease/0 head of death
Control group 3/1 death Onset of 6/death of 2 8/3 deaths from illness
According to the data, the disease control rate and the death rate of the livestock heat-clearing anti-inflammatory Chinese herbal medicine composition are obviously reduced and changed within the set time period of the high-temperature season with high epidemic diseases, so that the good heat-clearing anti-inflammatory effects are achieved, and the treatment and prevention purposes of the livestock heat-clearing anti-inflammatory Chinese herbal medicine composition are realized.
The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and the technical solutions in the idea of the present invention all belong to the protection scope of the present invention, it should be noted that, for those skilled in the art, several modifications and decorations without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims (3)

1. A heat-clearing anti-inflammatory Chinese herbal medicine composition for animals is characterized in that: the Chinese herbal medicine composition comprises the following components in parts by mass: 20 parts of honeysuckle, 20 parts of isatis root, 15 parts of wild chrysanthemum flower, 10 parts of common andrographis herb, 10 parts of baical skullcap root, 10 parts of dried rehmannia root, 10 parts of coptis root, 8 parts of weeping forsythia capsule, 5 parts of gentian, 20 parts of feed leavening agent and 300 parts of corn flour.
2. The heat-clearing anti-inflammatory Chinese herbal medicine composition for livestock according to claim 1, which is characterized in that: the preparation method comprises the following steps:
(1) the proportioning materials with the mass part formula larger than 80 meshes are prepared by adopting a traditional Chinese medicine grinder to grind samples one by one to pass through a standard sieve with the size of 80 meshes, and then the samples enter a three-dimensional mixer to be fully mixed to prepare a mixture for fermentation and standby.
(2) Adding drinking water into the mixture for fermentation until the water content is 50%, fermenting in a fermentation chamber at 25-35 deg.C for 72 hr, and cooling to room temperature for use.
3. The heat-clearing anti-inflammatory Chinese herbal medicine composition for livestock according to claims 1 and 2, which is characterized in that: when the livestock needs to be prevented and treated by clearing heat and resisting inflammation, 100 parts by mass of the feed eaten by the livestock is mixed with 15 parts by mass of the heat-clearing and anti-inflammation Chinese herbal medicine composition for livestock, and then the mixture is supplied to the livestock to eat.
CN202010338595.7A 2020-04-26 2020-04-26 Heat-clearing anti-inflammatory Chinese herbal medicine composition for livestock Pending CN111317766A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010338595.7A CN111317766A (en) 2020-04-26 2020-04-26 Heat-clearing anti-inflammatory Chinese herbal medicine composition for livestock

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Application Number Priority Date Filing Date Title
CN202010338595.7A CN111317766A (en) 2020-04-26 2020-04-26 Heat-clearing anti-inflammatory Chinese herbal medicine composition for livestock

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Publication Number Publication Date
CN111317766A true CN111317766A (en) 2020-06-23

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1401369A (en) * 2002-09-27 2003-03-12 长春市动物药厂 Antiviral, antibacterial and antiinflammatory herbal injection for treating livestock and fowl infectious disease
CN105748675A (en) * 2014-12-16 2016-07-13 天津佳瑞兴科技发展有限公司 Virus-resistant inflammation-diminishing veterinary traditional Chinese medicine particle for treating poultry infectious diseases
CN106511675A (en) * 2016-11-08 2017-03-22 广西罗城新科双全有机食品有限公司 Medicine for preventing and treating poultry diseases and preparation method of medicine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1401369A (en) * 2002-09-27 2003-03-12 长春市动物药厂 Antiviral, antibacterial and antiinflammatory herbal injection for treating livestock and fowl infectious disease
CN105748675A (en) * 2014-12-16 2016-07-13 天津佳瑞兴科技发展有限公司 Virus-resistant inflammation-diminishing veterinary traditional Chinese medicine particle for treating poultry infectious diseases
CN106511675A (en) * 2016-11-08 2017-03-22 广西罗城新科双全有机食品有限公司 Medicine for preventing and treating poultry diseases and preparation method of medicine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
孙耀华: "猪流感与防治措施", 《吉林畜牧兽医》 *

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Application publication date: 20200623