CN111297847B - 九翅豆蔻提取物在制备α-葡萄糖苷酶抑制剂药物中的应用 - Google Patents
九翅豆蔻提取物在制备α-葡萄糖苷酶抑制剂药物中的应用 Download PDFInfo
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- CN111297847B CN111297847B CN202010177287.0A CN202010177287A CN111297847B CN 111297847 B CN111297847 B CN 111297847B CN 202010177287 A CN202010177287 A CN 202010177287A CN 111297847 B CN111297847 B CN 111297847B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- AIDS & HIV (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202010177287.0A CN111297847B (zh) | 2020-03-13 | 2020-03-13 | 九翅豆蔻提取物在制备α-葡萄糖苷酶抑制剂药物中的应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN202010177287.0A CN111297847B (zh) | 2020-03-13 | 2020-03-13 | 九翅豆蔻提取物在制备α-葡萄糖苷酶抑制剂药物中的应用 |
Publications (2)
Publication Number | Publication Date |
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CN111297847A CN111297847A (zh) | 2020-06-19 |
CN111297847B true CN111297847B (zh) | 2021-08-06 |
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CN202010177287.0A Active CN111297847B (zh) | 2020-03-13 | 2020-03-13 | 九翅豆蔻提取物在制备α-葡萄糖苷酶抑制剂药物中的应用 |
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Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112521439B (zh) * | 2020-12-15 | 2022-02-11 | 广东省微生物研究所(广东省微生物分析检测中心) | 桦褐孔菌醇F及其在制备α-葡萄糖苷酶抑制剂药物的应用 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006008115A1 (en) * | 2004-07-16 | 2006-01-26 | Universidad Austral De Chile | Diterpenic labdans as immunostimulants for treating infectious diseases |
CN1921872A (zh) * | 2004-02-03 | 2007-02-28 | 智利南方大学 | 用于激活PPR-γ受体而治疗自身免疫性疾病和阿尔茨海默病的提取自穿心莲的半日花烷型二萜类组合物 |
CN103304523A (zh) * | 2012-11-30 | 2013-09-18 | 暨南大学 | 穿心莲内酯一氧化氮供体类化合物及其制备方法和应用 |
CN105085449A (zh) * | 2014-05-13 | 2015-11-25 | 上海中医药大学 | 半日花型二萜衍生物及其制备方法和应用 |
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2020
- 2020-03-13 CN CN202010177287.0A patent/CN111297847B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1921872A (zh) * | 2004-02-03 | 2007-02-28 | 智利南方大学 | 用于激活PPR-γ受体而治疗自身免疫性疾病和阿尔茨海默病的提取自穿心莲的半日花烷型二萜类组合物 |
WO2006008115A1 (en) * | 2004-07-16 | 2006-01-26 | Universidad Austral De Chile | Diterpenic labdans as immunostimulants for treating infectious diseases |
CN103304523A (zh) * | 2012-11-30 | 2013-09-18 | 暨南大学 | 穿心莲内酯一氧化氮供体类化合物及其制备方法和应用 |
CN105085449A (zh) * | 2014-05-13 | 2015-11-25 | 上海中医药大学 | 半日花型二萜衍生物及其制备方法和应用 |
Non-Patent Citations (3)
Title |
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Labdane Diterpenes from the Aerial Parts of Curcuma comosa Enhance Fetal Hemoglobin Production in an Erythroid Cell Line;Ratchanaporn Chokchaisiri et al.;《J. Nat. Prod.》;20100423;第73卷;第724-728页 * |
Molecular docking and inhibition studies of a-amylase activity by labdane diterpenes from Alpinia nigra seeds;Sudipta Ghosh et al.;《Med Chem Res》;20140610;第1-18页 * |
New Labdane diterpenes as intestinal a-glucosidase inhibitor from antihyperglycemic extract of Hedychium spicatum (Ham. Ex Smith) rhizomes;P. Prabhakar Reddy et al.;《Bioorganic & Medicinal Chemistry Letters》;20090316;第19卷;第2562-2565页 * |
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CN111297847A (zh) | 2020-06-19 |
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Address after: 510316, 10, pomegranate Road, Guangzhou, Guangdong, Haizhuqu District Patentee after: Institute of bioengineering, Guangdong Academy of Sciences Address before: 510316, 10, pomegranate Road, Guangzhou, Guangdong, Haizhuqu District Patentee before: GUANGDONG PROVINCIAL BIOENGINEERING INSTITUTE (GUANGZHOU SUGARCANE INDUSTRY RESEARCH INSTITUTE) |
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Effective date of registration: 20220623 Address after: No.10, shiliugang Road, Haizhu District, Guangzhou City, Guangdong Province 510000 Patentee after: Nanfan Seed Industry Research Institute Guangdong Academy of Sciences Address before: 510316, 10, pomegranate Road, Guangzhou, Guangdong, Haizhuqu District Patentee before: Institute of bioengineering, Guangdong Academy of Sciences |
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