CN111246866A - 包含细菌菌株的组合物 - Google Patents

包含细菌菌株的组合物 Download PDF

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Publication number
CN111246866A
CN111246866A CN201880055780.6A CN201880055780A CN111246866A CN 111246866 A CN111246866 A CN 111246866A CN 201880055780 A CN201880055780 A CN 201880055780A CN 111246866 A CN111246866 A CN 111246866A
Authority
CN
China
Prior art keywords
composition
enterococcus
bacterial strain
use according
diversity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201880055780.6A
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English (en)
Chinese (zh)
Inventor
伊姆克·伊丽莎白·马尔德
肖恩·玛丽·麦克罗斯基
海琳·萨维尼亚克
伊恩·杰弗里
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
4D Pharma Research Ltd
Original Assignee
4D Pharma Research Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1712857.0A external-priority patent/GB201712857D0/en
Priority claimed from GBGB1800866.4A external-priority patent/GB201800866D0/en
Application filed by 4D Pharma Research Ltd filed Critical 4D Pharma Research Ltd
Publication of CN111246866A publication Critical patent/CN111246866A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/32—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/324—Foods, ingredients or supplements having a functional effect on health having an effect on the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201880055780.6A 2017-08-10 2018-08-10 包含细菌菌株的组合物 Pending CN111246866A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB1712857.0A GB201712857D0 (en) 2017-08-10 2017-08-10 Compositions comprising bacterial strains
GB1712857.0 2017-08-10
GB1800866.4 2018-01-19
GBGB1800866.4A GB201800866D0 (en) 2018-01-19 2018-01-19 Compositions comprising bacterial strains
EP18183642 2018-07-16
EP18183642.0 2018-07-16
PCT/EP2018/071831 WO2019030411A1 (en) 2017-08-10 2018-08-10 COMPOSITIONS COMPRISING BACTERIAL STRAINS

Publications (1)

Publication Number Publication Date
CN111246866A true CN111246866A (zh) 2020-06-05

Family

ID=63524238

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880055780.6A Pending CN111246866A (zh) 2017-08-10 2018-08-10 包含细菌菌株的组合物

Country Status (14)

Country Link
US (1) US20200237834A1 (enExample)
EP (1) EP3664824A1 (enExample)
JP (1) JP2020529431A (enExample)
KR (1) KR20200038970A (enExample)
CN (1) CN111246866A (enExample)
AU (1) AU2018312955A1 (enExample)
BR (1) BR112020002212A2 (enExample)
CA (1) CA3072013A1 (enExample)
IL (1) IL272491A (enExample)
MA (1) MA49982A (enExample)
MX (1) MX392976B (enExample)
SG (1) SG11202001174XA (enExample)
TW (1) TW201919674A (enExample)
WO (1) WO2019030411A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112004543A (zh) * 2018-03-19 2020-11-27 4D制药研究有限公司 包含细菌菌株的组合物
CN117903980A (zh) * 2024-01-05 2024-04-19 四川大学 一种海氏肠球菌及其应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI731279B (zh) * 2018-11-21 2021-06-21 葡萄王生技股份有限公司 發酵乳桿菌gkf3、含其之組合物及改善精神失調之用途
KR102623834B1 (ko) * 2020-07-13 2024-01-12 서울대학교병원 에스트로겐을 포함하는 장내 미생물총 변화를 통한 남성의 대장암 예방 또는 치료용 조성물
JP2024534722A (ja) * 2021-09-20 2024-09-25 ハドソン インスティテュート オブ メディカル リサーチ 生物療法剤エンテロコッカス属単離株

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160303172A1 (en) * 2013-11-21 2016-10-20 Institut Gustave Roussy Microbiota composition, as a marker of responsiveness to chemotherapy, and use of microbial modulators (pre-, pro- or synbiotics) for improving the efficacy of a cancer treatment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9107305D0 (en) * 1991-04-08 1991-05-22 Unilever Plc Probiotic
JPH08259450A (ja) * 1995-03-17 1996-10-08 Nichinichi Seiyaku Kk インターフェロン産生増強剤
DE102010013209A1 (de) * 2010-03-29 2011-09-29 Technische Universität München Diarrhö-Prophylaktikum
GB201520497D0 (en) * 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
CA3005781C (en) * 2015-11-20 2019-01-22 4D Pharma Research Limited Compositions comprising bacterial strains

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160303172A1 (en) * 2013-11-21 2016-10-20 Institut Gustave Roussy Microbiota composition, as a marker of responsiveness to chemotherapy, and use of microbial modulators (pre-, pro- or synbiotics) for improving the efficacy of a cancer treatment
CN106170557A (zh) * 2013-11-21 2016-11-30 古斯达威罗斯研究所 作为化疗应答标志物的微生物群组合物，以及微生物调节剂(益生元、益生菌或合生元)用于提高癌症治疗效力的用途

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ROMAIN DAILLÈRE等: "Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects", 《IMMUNITY》 *
刘长建等: "鹑鸡肠球菌m661的抗氧化、降胆固醇作用", 《食品科学》 *
李宇颖编著: "环磷酰胺", 《肾内科速查》 *
陈华新等: "免疫抑制剂", 《免疫力与健康》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112004543A (zh) * 2018-03-19 2020-11-27 4D制药研究有限公司 包含细菌菌株的组合物
CN117903980A (zh) * 2024-01-05 2024-04-19 四川大学 一种海氏肠球菌及其应用

Also Published As

Publication number Publication date
CA3072013A1 (en) 2019-02-14
US20200237834A1 (en) 2020-07-30
JP2020529431A (ja) 2020-10-08
MX392976B (es) 2025-03-24
EP3664824A1 (en) 2020-06-17
BR112020002212A2 (pt) 2020-07-28
MX2020001632A (es) 2022-06-08
SG11202001174XA (en) 2020-03-30
KR20200038970A (ko) 2020-04-14
WO2019030411A1 (en) 2019-02-14
AU2018312955A1 (en) 2020-04-02
IL272491A (en) 2020-03-31
MA49982A (fr) 2020-06-17
TW201919674A (zh) 2019-06-01

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