CN111229349A - A pipette that can automatically cover the tip - Google Patents

A pipette that can automatically cover the tip Download PDF

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CN111229349A
CN111229349A CN202010184398.4A CN202010184398A CN111229349A CN 111229349 A CN111229349 A CN 111229349A CN 202010184398 A CN202010184398 A CN 202010184398A CN 111229349 A CN111229349 A CN 111229349A
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axis
suction head
pipette
claw
tip
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CN111229349B (en
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孙立香
武维东
单秀文
靖文
郑一波
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Yancheng Vocational Institute of Industry Technology
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Yancheng Vocational Institute of Industry Technology
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids

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Abstract

本发明公开了一种可自动套取吸头的移液器,包括:底板、设置在底板上的三维运动机构、设置在三维运动机构上的吸头抓取机构、设置在吸头抓取机构上的移液吸管以及设置在底板上的用于放置吸头盒的安装槽;所述三维运动机构用于带动所述吸头抓取机构进行三维移动;所述吸头抓取机构包括固定套管以及设置在所述固定套管上的抓爪组件,所述移液吸管与所述固定套管的上端连通,所述抓爪组件用于抓取所述吸头盒中的指定位置上的吸头,所述固定套管的下端用于与所述抓爪组件抓取的吸头连通。本发明通过三维运动机构带动吸头抓取机构进行三维移动,能实现移液吸管自动套取吸头的功能,且能保证套取吸头的稳定性,同时也能很好的保护吸头和移液吸管。

Figure 202010184398

The invention discloses a pipette capable of automatically covering a suction head, comprising: a base plate, a three-dimensional movement mechanism arranged on the base plate, a suction head grabbing mechanism arranged on the three-dimensional movement mechanism, and a suction head grabbing mechanism arranged on the base plate. The pipette pipette on the bottom plate and the installation slot for placing the tip box on the bottom plate; the three-dimensional motion mechanism is used to drive the suction head grabbing mechanism to move in three dimensions; the suction head grabbing mechanism includes a fixed sleeve A pipe and a gripper assembly arranged on the fixed sleeve, the pipette is communicated with the upper end of the fixed sleeve, and the gripper assembly is used for grabbing a specified position in the tip box. A suction head, the lower end of the fixed sleeve is used for communicating with the suction head grasped by the gripper assembly. The invention drives the suction head grasping mechanism to move three-dimensionally through the three-dimensional motion mechanism, can realize the function of automatically covering the suction head with the pipette, can ensure the stability of the suction head, and can also well protect the suction head and the suction head. Pipette.

Figure 202010184398

Description

一种可自动套取吸头的移液器A pipette that can automatically cover the tip

技术领域technical field

本发明涉及移液设备领域,特别涉及一种可自动套取吸头的移液器。The invention relates to the field of pipetting equipment, in particular to a pipette that can automatically cover a pipette tip.

背景技术Background technique

微量移液器吸头(或称枪头)常见于生物及医药实验室,是实验中最常用的耗材。现有技术中,有大量手动操作的移液器,但其移液效率低、费时费力,所以也出现了一些自动移液设备,其通常是通过一个二维或三维运动机构装载移液组件(包括移液管和与其连接的外部的液路单元,有些移液管上也可能还连接有针头),从而驱动移液组件的移动到指定位置,再利用移液管套取吸头,然后进行相关移液工作。移液管套取吸头后需要保证吸头与移液管能牢固连接,防止移液过程中掉落,所以一般可通过以下方案实现,其中一种方式为:将移液管的末端尺寸设计比吸头小,通过压力使移液管挤入吸头内,此时在套取吸头时需要通过移液管对吸头施加较大的作用力,以保证吸头牢固套在移液管上;但这样容易时吸头和装载吸头的吸头盒变形或损坏,另外也容易损坏移液管。另一种方式为在吸头和/或移液管设置相关的适配结构,通过适配机构实现吸头和移液管的连接;但其存在如下缺点,通常该适配结构较为复杂,另外在连接时需要移液管相对吸头进行一定的旋转才能牢固连接,这样会增加运动机构的复杂性。所以,现在需要一种更可靠的方案。Micropipette tips (or pipette tips) are commonly found in biological and medical laboratories and are the most commonly used consumables in experiments. In the prior art, there are a large number of manually-operated pipettes, but their pipetting efficiency is low, time-consuming and labor-intensive, so there are also some automatic pipetting devices, which usually load pipetting components through a two-dimensional or three-dimensional motion mechanism ( Including the pipette and the external liquid circuit unit connected to it, some pipettes may also be connected with a needle), so as to drive the movement of the pipetting assembly to the designated position, and then use the pipette cover to take the tip, and then carry out Related pipetting work. After the pipette cover takes the tip, it is necessary to ensure that the tip and the pipette can be firmly connected to prevent it from falling during the pipetting process, so it can generally be achieved through the following schemes, one of which is: design the size of the end of the pipette It is smaller than the pipette tip, and the pipette is squeezed into the pipette head by pressure. At this time, when taking the pipette tip, it is necessary to exert a large force on the pipette tip to ensure that the pipette tip is firmly sheathed in the pipette. However, it is easy to deform or damage the tips and the tip box containing the tips, and it is also easy to damage the pipette. Another way is to set a related fitting structure on the suction head and/or the pipette, and realize the connection between the suction head and the pipette through the fitting mechanism; however, it has the following disadvantages, usually the fitting structure is more complicated, and in addition When connecting, the pipette needs to be rotated relative to the tip to be firmly connected, which will increase the complexity of the movement mechanism. Therefore, a more reliable solution is now required.

发明内容SUMMARY OF THE INVENTION

本发明所要解决的技术问题在于针对上述现有技术中的不足,提供一种可自动套取吸头的移液器。The technical problem to be solved by the present invention is to provide a pipette that can automatically cover a pipette tip in view of the above deficiencies in the prior art.

为解决上述技术问题,本发明采用的技术方案是:一种可自动套取吸头的移液器,包括:底板、设置在所述底板上的三维运动机构、设置在所述三维运动机构上的吸头抓取机构、设置在所述吸头抓取机构上的移液吸管以及设置在所述底板上的用于放置所述吸头盒的安装槽;In order to solve the above-mentioned technical problems, the technical solution adopted in the present invention is: a pipette capable of automatically sheathing a suction head, comprising: a bottom plate, a three-dimensional motion mechanism arranged on the bottom plate, and a three-dimensional motion mechanism arranged on the three-dimensional motion mechanism. a suction-tip grabbing mechanism, a pipette pipette arranged on the suction-tip grabbing mechanism, and a mounting groove arranged on the bottom plate for placing the suction-tip box;

所述三维运动机构用于带动所述吸头抓取机构进行三维移动;The three-dimensional motion mechanism is used to drive the suction head grasping mechanism to move three-dimensionally;

所述吸头抓取机构包括固定套管以及设置在所述固定套管上的抓爪组件,所述移液吸管与所述固定套管的上端连通,所述抓爪组件用于抓取所述吸头盒中的指定位置上的吸头,所述固定套管的下端用于与所述抓爪组件抓取的吸头连通。The suction head grasping mechanism includes a fixed sleeve and a grasping claw assembly arranged on the fixed sleeve, the pipette is communicated with the upper end of the fixed sleeve, and the grasping claw assembly is used for grasping the The suction head at the designated position in the suction head box, and the lower end of the fixed sleeve is used to communicate with the suction head grasped by the gripper assembly.

优选的是,所述三维运动机构包括设置在所述底板上的X轴运动组件、设置在所述X轴运动组件上的Y轴运动组件以及设置在所述Y轴运动组件上的Z轴运动组件;Preferably, the three-dimensional motion mechanism includes an X-axis motion component provided on the base plate, a Y-axis motion component provided on the X-axis motion component, and a Z-axis motion component provided on the Y-axis motion component components;

所述Z轴运动组件包括设置在所述Y轴运动组件上的Z轴安装板、设置在所述Z轴安装板上的Z轴电机、与所述Z轴电机驱动连接的Z轴丝杆以及与所述Z轴丝杆螺纹配合的Z轴滑套;The Z-axis motion assembly includes a Z-axis mounting plate disposed on the Y-axis motion assembly, a Z-axis motor disposed on the Z-axis mounting plate, a Z-axis screw drivingly connected to the Z-axis motor, and A Z-axis sliding sleeve matched with the Z-axis screw thread;

所述吸头抓取机构通过连接板固接在所述Z轴滑套上。The suction head grabbing mechanism is fixed on the Z-axis sliding sleeve through a connecting plate.

优选的是,所述底板上设置有安装支架,所述X轴运动组件包括设置在所述安装支架上的X轴电机、与所述X轴电机驱动连接的X轴丝杆以及套设在所述X轴丝杆上且与所述X轴丝杆螺纹配合的X轴滑块;Preferably, a mounting bracket is provided on the base plate, and the X-axis motion assembly includes an X-axis motor arranged on the mounting bracket, an X-axis screw drivingly connected with the X-axis motor, and an X-axis screw sleeved on the mounting bracket. The X-axis slider on the X-axis screw and threadedly matched with the X-axis screw;

所述Y轴运动组件包括设置在所述X轴滑块上的Y轴安装板、设置在所述Y轴安装板上的Y轴电机、与所述Y轴电机驱动连接的Y轴丝杆以及套设在所述Y轴丝杆上且与所述Y轴丝杆螺纹配合的Y轴滑块;The Y-axis motion assembly includes a Y-axis mounting plate disposed on the X-axis slider, a Y-axis motor disposed on the Y-axis mounting plate, a Y-axis screw drivingly connected to the Y-axis motor, and a Y-axis slider sleeved on the Y-axis screw and threadedly matched with the Y-axis screw;

所述Z轴运动组件的Z轴安装板设置在所述Y轴滑块上。The Z-axis mounting plate of the Z-axis motion component is arranged on the Y-axis slider.

优选的是,所述固定套管的下端连接有锥体管段,所述锥体管段用于插入所述抓爪组件抓取的吸头内。Preferably, the lower end of the fixing sleeve is connected with a cone pipe section, and the cone pipe section is used to be inserted into the suction head grasped by the gripper assembly.

优选的是,所述抓爪组件包括对称设置在所述固定套管外壁上的2个抓爪或是两两对称设置所述固定套管外壁上的4个抓爪;Preferably, the gripper assembly comprises two grippers symmetrically arranged on the outer wall of the fixed sleeve or four grippers symmetrically arranged on the outer wall of the fixed sleeve;

所述抓爪的上端与所述固定套管的外壁可转动连接,所述抓爪的中部与所述固定套管外壁之间连接有拉紧弹簧,所述抓爪的下端内侧具有引导斜面,所述引导斜面与所述吸头接触而受力时所述抓爪的下端向外旋转。The upper end of the gripping claw is rotatably connected with the outer wall of the fixing sleeve, a tension spring is connected between the middle part of the gripping claw and the outer wall of the fixing sleeve, and the inner side of the lower end of the gripping claw has a guiding slope, The lower end of the gripper rotates outward when the guide slope is in contact with the suction head and is stressed.

优选的是,所述抓爪包括爪身和连接在所述抓身下端的爪头,所述爪身的内侧沿长度方向开设有容纳槽,处于所述容纳槽两侧的爪身的内侧壁上设置有用于与所述固定套管的外壁贴合的弧形面;Preferably, the gripping claw comprises a claw body and a claw head connected to the lower end of the gripping body, the inner side of the claw body is provided with a accommodating groove along the length direction, and the inner side walls of the claw body on both sides of the accommodating groove An arc surface for fitting with the outer wall of the fixed sleeve is provided on it;

所述爪身的上端开设有轴孔;The upper end of the claw body is provided with a shaft hole;

所述爪头的内侧壁上形成所述引导斜面,所述爪头的宽度大于爪身的宽度,在所述爪头的上表面上处于所述爪身的内侧部分形成固定平面。The guide slope is formed on the inner side wall of the claw head, the width of the claw head is larger than the width of the claw body, and a fixed plane is formed on the upper surface of the claw head on the inner side of the claw body.

优选的是,所述吸头包括吸头本体以及设置在所述吸头本体上端的环形凸沿,所述抓爪组件抓取吸头后,所述环形凸沿卡设在所述固定平面上。Preferably, the suction head includes a suction head body and an annular convex edge disposed on the upper end of the suction head body, and after the gripper assembly grabs the suction head, the annular convex edge is clamped on the fixing plane .

优选的是,所述固定套管外壁上由上至下依次设置有转动连接块和弹簧安装块,所述转动连接块上设置有用于转动连接所述爪身上端的连接轴;Preferably, a rotating connecting block and a spring mounting block are sequentially arranged on the outer wall of the fixed sleeve from top to bottom, and the rotating connecting block is provided with a connecting shaft for rotatingly connecting the upper end of the claw body;

所述拉紧弹簧的一端与所述弹簧安装块连接,另一端与所述容纳槽的内壁连接。One end of the tension spring is connected with the spring mounting block, and the other end is connected with the inner wall of the accommodating groove.

优选的是,所述安装槽的外周设置有四个用于固定放置在所述安装槽内的吸头盒的固定块;Preferably, the outer circumference of the installation groove is provided with four fixing blocks for fixing the tip box placed in the installation groove;

所述固定块的内壁上开设有弹片槽,所述弹片槽内设置有弧形弹片。The inner wall of the fixing block is provided with an elastic sheet groove, and an arc-shaped elastic sheet is arranged in the elastic sheet groove.

优选的是,所述弧形弹片的外表面上设置有定位顶球,所述弧形弹片的内表面上设置有压簧;Preferably, a positioning ball is provided on the outer surface of the arc-shaped elastic sheet, and a compression spring is provided on the inner surface of the arc-shaped elastic sheet;

所述吸头盒的外壁上开设有供所述定位顶球配合插入的定位孔。The outer wall of the suction head box is provided with a positioning hole for the matching insertion of the positioning ball.

本发明的有益效果是:本发明的可自动套取吸头的移液器,通过三维运动机构带动吸头抓取机构进行三维移动,能实现移液吸管自动套取吸头的功能,且能保证套取吸头的稳定性,同时也能很好的保护吸头和移液吸管;The beneficial effects of the present invention are as follows: the pipette capable of automatically sheathing the pipette of the present invention drives the grabbing mechanism of the pipette to move in three dimensions through the three-dimensional motion mechanism, which can realize the function of automatically sheathing the pipette with the pipette, and can To ensure the stability of the pipette tip, and also to protect the tip and pipette well;

本发明的吸头抓取机构套取吸头时,只需要对吸头施加轻微的向下的压力即可牢固抓取吸头,能避免因向下压力过大而使吸头或是吸头盒变形或损坏;套取过程中,移液吸管不会与吸头直接接触,能防止损坏移液吸管。When the suction head grabbing mechanism of the present invention covers the suction head, it only needs to apply a slight downward pressure to the suction head to firmly grasp the suction head, which can avoid the suction head or the suction head due to excessive downward pressure. The box is deformed or damaged; the pipette will not be in direct contact with the tip during the extraction process, which can prevent damage to the pipette.

附图说明Description of drawings

图1为本发明的可自动套取吸头的移液器的结构示意图;1 is a schematic structural diagram of a pipette that can automatically cover a tip according to the present invention;

图2为本发明的可自动套取吸头的移液器的另一个视角的结构示意图;FIG. 2 is a schematic structural diagram of another perspective of the pipette capable of automatically covering the tip of the present invention;

图3为本发明的吸头抓取机构的结构示意图;3 is a schematic structural diagram of the suction head grabbing mechanism of the present invention;

图4为本发明的抓爪的结构示意图;4 is a schematic structural diagram of a gripper of the present invention;

图5为本发明的固定套管的结构示意图;5 is a schematic structural diagram of a fixed sleeve of the present invention;

图6为本发明的固定套管与抓爪配合的结构示意图;6 is a schematic structural diagram of the fixing sleeve and the gripper of the present invention;

图7为本发明的吸头的结构示意图;Fig. 7 is the structural schematic diagram of the suction head of the present invention;

图8为本发明的吸头抓取机构抓取吸头的一种状态的示意图;8 is a schematic diagram of a state in which the suction head grabbing mechanism of the present invention grabs the suction head;

图9为本发明的吸头抓取机构抓取吸头的另一种状态的示意图;9 is a schematic diagram of another state in which the suction head grasping mechanism of the present invention grasps the suction head;

图10为本发明的底板的结构示意图;Fig. 10 is the structural representation of the bottom plate of the present invention;

图11为本发明的吸头盒的结构示意图;11 is a schematic structural diagram of the tip box of the present invention;

图12为本发明的固定块的结构示意图;12 is a schematic structural diagram of a fixed block of the present invention;

图13为本发明的固定块的剖视结构示意图。FIG. 13 is a schematic cross-sectional structural diagram of the fixing block of the present invention.

附图标记说明:Description of reference numbers:

1—底板;10—安装支架;11—安装槽;12—固定块;13—弹片槽;14—弧形弹片;15—定位顶球;16—压簧;1—bottom plate; 10—installation bracket; 11—installation slot; 12—fixed block; 13—shrapnel slot; 14—arc shrapnel; 15—positioning top ball; 16—compression spring;

2—X轴运动组件;20—X轴电机;21—X轴丝杆;22—X轴滑块;23—X轴光耦;24—X挡片;2—X-axis motion components; 20—X-axis motor; 21—X-axis screw; 22—X-axis slider; 23—X-axis optocoupler; 24—X-block;

3—Y轴运动组件;30—Y轴安装板;31—Y轴电机;32—Y轴丝杆;33—Y轴滑块;34—Y轴光耦;35—Y挡片;3-Y-axis motion components; 30-Y-axis mounting plate; 31-Y-axis motor; 32-Y-axis screw; 33-Y-axis slider; 34-Y-axis optocoupler; 35-Y-block;

4—Z轴运动组件;40—Z轴安装板;41—Z轴电机;42—Z轴丝杆;43—Z轴滑套;44—连接板;45—Z轴光耦;46—Z挡片;4—Z-axis motion components; 40—Z-axis mounting plate; 41—Z-axis motor; 42—Z-axis screw; 43—Z-axis sliding sleeve; 44—connecting plate; 45—Z-axis optocoupler; 46—Z block piece;

5—吸头抓取机构;50—固定套管;51—抓爪组件;52—抓爪;53—爪身;54—爪头;500—锥体管段;501—转动连接块;502—弹簧安装块;503—拉紧弹簧;504—连接轴;505—连通孔;506—弧形缺口;530—容纳槽;531—弧形面;532—轴孔;540—引导斜面;541—固定平面;5—Suction head grabbing mechanism; 50—Fixed sleeve; 51—Gripper assembly; 52—Gripper; 53—Claw body; 54—Claw head; 500—Conical pipe section; 501—Rotating connecting block; 502—Spring Mounting block; 503—tensioning spring; 504—connecting shaft; 505—connecting hole; 506—arc notch; 530—accommodating groove; 531—arc surface; 532—shaft hole; ;

6—移液吸管;6—pipette;

7—吸头盒;70—吸头孔;71—定位孔;7—tip box; 70—tip hole; 71—positioning hole;

8—吸头;80—吸头本体;81—环形凸沿。8—Suction head; 80—Suction head body; 81—Annular convex edge.

具体实施方式Detailed ways

下面结合实施例对本发明做进一步的详细说明,以令本领域技术人员参照说明书文字能够据以实施。The present invention will be further described in detail below with reference to the embodiments, so that those skilled in the art can implement according to the description.

应当理解,本文所使用的诸如“具有”、“包含”以及“包括”术语并不排除一个或多个其它元件或其组合的存在或添加。It should be understood that terms such as "having", "comprising" and "including" as used herein do not exclude the presence or addition of one or more other elements or combinations thereof.

如图1所示,本实施例的一种可自动套取吸头8的移液器,包括:底板1、设置在底板1上的三维运动机构、设置在三维运动机构上的吸头抓取机构5、设置在吸头抓取机构5上的移液吸管6以及设置在底板1上的用于放置吸头盒7的安装槽11;As shown in FIG. 1 , a pipette capable of automatically covering a suction head 8 according to the present embodiment includes: a base plate 1 , a three-dimensional motion mechanism arranged on the base plate 1 , and a suction head grasping mechanism arranged on the three-dimensional motion mechanism The mechanism 5, the pipette 6 arranged on the tip grabbing mechanism 5, and the mounting groove 11 arranged on the bottom plate 1 for placing the tip box 7;

三维运动机构用于带动吸头抓取机构5进行三维移动;The three-dimensional motion mechanism is used to drive the suction head grasping mechanism 5 to move three-dimensionally;

吸头抓取机构5包括固定套管50以及设置在固定套管50上的抓爪组件51,移液吸管6与固定套管50的上端连通,抓爪组件51用于抓取吸头盒7中的指定位置上的吸头8,固定套管50的下端用于与抓爪组件51抓取的吸头8连通。The tip grabbing mechanism 5 includes a fixed sleeve 50 and a gripper assembly 51 arranged on the fixed sleeve 50. The pipette 6 communicates with the upper end of the fixed sleeve 50, and the gripper assembly 51 is used to grab the tip box 7 The lower end of the fixed sleeve 50 is used to communicate with the suction head 8 grasped by the gripper assembly 51 .

本发明中,移液吸管6与固定套管50的上端连通,三维运动机构带动固定套管50以及其上的抓爪组件51、移液吸管6一起进行三维运动,以移动至吸头盒7中的指定位置上的吸头8上方,然后再一起下移,通过抓爪组件51抓取吸头8,此时固定套管50的下端与抓取的吸头8连通,从而使移液吸管6与吸头8实现连通,然后可运动至其他位置进行相关移液操作。本发明中,不采用常规移液设备中通过移液吸管6本身去抓取吸头8的方案,而是通过一个专门的抓爪组件51抓取吸头8,然后固定住并使移液吸管6与吸头8连通。能保证套取吸头8的稳定性,同时也能很好的保护吸头8和移液吸管6。可以理解的是,移液吸管6的末端也可连接针头。另外,移液吸管6上端连接外部必要的常规液路系统(本发明中不再具体说明),以实现吸液的功能。以上为本发明的基本构思,以下在其基础上提供进一步详细的实施例。In the present invention, the pipette 6 is communicated with the upper end of the fixed sleeve 50, and the three-dimensional motion mechanism drives the fixed sleeve 50, the gripper assembly 51 and the pipette 6 to perform three-dimensional movement together to move to the tip box 7 Above the suction head 8 at the designated position in the pipette, and then move down together, grab the suction head 8 through the grasping claw assembly 51, at this time, the lower end of the fixed sleeve 50 is communicated with the grasped suction head 8, so that the pipette pipette 6 communicates with the suction head 8, and then can move to other positions for related pipetting operations. In the present invention, instead of using the conventional pipetting device to grab the tip 8 through the pipette 6 itself, a special gripper assembly 51 is used to grab the tip 8, and then fix and make the pipette 6 communicates with the suction head 8 . The stability of the suction tip 8 can be ensured, and at the same time, the suction tip 8 and the pipette 6 can be well protected. It is understood that the end of the pipette 6 can also be connected to a needle. In addition, the upper end of the pipette 6 is connected to an external necessary conventional liquid circuit system (not described in detail in the present invention), so as to realize the function of liquid suction. The above is the basic idea of the present invention, and further detailed embodiments are provided on the basis of the above.

在一种优选的实施例中,参照图1和2,三维运动机构包括设置在底板1上的X轴运动组件2、设置在X轴运动组件2上的Y轴运动组件3以及设置在Y轴运动组件3上的Z轴运动组件4;Z轴运动组件4包括设置在Y轴运动组件3上的Z轴安装板40、设置在Z轴安装板40上的Z轴电机41、与Z轴电机41驱动连接的Z轴丝杆42以及与Z轴丝杆42螺纹配合的Z轴滑套43;吸头抓取机构5通过连接板44固接在Z轴滑套43上。通过Z轴电机41带动Z轴丝杆42转动,从而实现与Z轴丝杆42螺纹配合的Z轴滑套43的上下运动。In a preferred embodiment, referring to FIGS. 1 and 2 , the three-dimensional motion mechanism includes an X-axis motion component 2 provided on the base plate 1 , a Y-axis motion component 3 provided on the X-axis motion component 2 , and a Y-axis motion component 3 provided on the X-axis motion component 2 . The Z-axis motion assembly 4 on the motion assembly 3; the Z-axis motion assembly 4 includes a Z-axis mounting plate 40 provided on the Y-axis motion assembly 3, a Z-axis motor 41 provided on the Z-axis mounting plate 40, and a Z-axis motor 41 drives the connected Z-axis screw rod 42 and the Z-axis sliding sleeve 43 threadedly matched with the Z-axis screw rod 42 ; The Z-axis screw 42 is driven to rotate by the Z-axis motor 41 , thereby realizing the up and down movement of the Z-axis sliding sleeve 43 threaded with the Z-axis screw 42 .

底板1上设置有安装支架10,X轴运动组件2包括设置在安装支架10上的X轴电机20、与X轴电机20驱动连接的X轴丝杆21以及套设在X轴丝杆21上且与X轴丝杆21螺纹配合的X轴滑块22;A mounting bracket 10 is provided on the base plate 1, and the X-axis motion assembly 2 includes an X-axis motor 20 arranged on the mounting bracket 10, an X-axis screw 21 drivingly connected with the X-axis motor 20, and sleeved on the X-axis screw 21. and the X-axis slider 22 threadedly matched with the X-axis screw rod 21;

Y轴运动组件3包括设置在X轴滑块22上的Y轴安装板30、设置在Y轴安装板30上的Y轴电机31、与Y轴电机31驱动连接的Y轴丝杆32以及套设在Y轴丝杆32上且与Y轴丝杆32螺纹配合的Y轴滑块33;Z轴运动组件4的Z轴安装板40设置在Y轴滑块33上。The Y-axis motion assembly 3 includes a Y-axis mounting plate 30 disposed on the X-axis slider 22 , a Y-axis motor 31 disposed on the Y-axis mounting plate 30 , a Y-axis screw 32 drivingly connected to the Y-axis motor 31 , and a sleeve The Y-axis slider 33 is provided on the Y-axis screw 32 and is threadedly matched with the Y-axis screw 32 ; the Z-axis mounting plate 40 of the Z-axis motion assembly 4 is arranged on the Y-axis slider 33 .

本实施例中通过电机丝杆机构实现三维驱动,以将抓爪组件51、移液吸管6移动至指定的位置。In this embodiment, three-dimensional driving is realized by a motor screw mechanism, so as to move the gripper assembly 51 and the pipette 6 to a designated position.

在进一步的实施例中,三个方向上均设置有位置检测机构,以实现X、Y、Z三个方向上的零位的定位,位置检测机构包括槽型光耦和挡片。具体的,安装支架10上设置有X轴光耦23,X轴滑块22上设置有与X轴光耦23配合的X挡片24;Y轴安装板30上设置有Y轴光耦34,Y轴滑块33上设置有与Y轴光耦34配合的Y挡片35;Z轴安装板40上设置有Z轴光耦45,Z轴滑套43上设置有与Z轴光耦45配合的Z挡片46。In a further embodiment, a position detection mechanism is provided in the three directions to realize the positioning of the zero position in the three directions of X, Y, and Z, and the position detection mechanism includes a slot-type optocoupler and a blocking plate. Specifically, the mounting bracket 10 is provided with an X-axis optocoupler 23, the X-axis slider 22 is provided with an X-block 24 matched with the X-axis optocoupler 23; the Y-axis mounting plate 30 is provided with a Y-axis optocoupler 34, The Y-axis slider 33 is provided with a Y-block 35 that cooperates with the Y-axis optocoupler 34; The Z-block 46.

进一步的,固定套管50的下端连接有锥体管段500,锥体管段500用于插入抓爪组件51抓取的吸头8内。抓爪组件51包括对称设置在固定套管50外壁上的2个抓爪52或是两两对称设置固定套管50外壁上的4个抓爪52;本实施例中为2个;抓爪52的上端与固定套管50的外壁可转动连接,抓爪52的中部与固定套管50外壁之间连接有拉紧弹簧503,抓爪52的下端内侧具有引导斜面540,引导斜面540与吸头8接触而受力时抓爪52的下端向外旋转。固定套管50内开设有连通孔505。Further, the lower end of the fixing sleeve 50 is connected with a conical pipe section 500 , and the conical pipe section 500 is used to be inserted into the suction head 8 grasped by the gripper assembly 51 . The gripper assembly 51 includes two grippers 52 symmetrically arranged on the outer wall of the fixed sleeve 50 or four grippers 52 symmetrically arranged on the outer wall of the fixed sleeve 50; in this embodiment, there are two; the grippers 52 The upper end of the gripping claw 52 is rotatably connected to the outer wall of the fixing sleeve 50, a tension spring 503 is connected between the middle part of the gripper 52 and the outer wall of the fixing sleeve 50, and the inner side of the lower end of the gripping claw 52 has a guiding inclined surface 540, and the guiding inclined surface 540 is connected to the suction head. The lower end of the gripping claw 52 rotates outward when it is in contact and is stressed. A communication hole 505 is opened in the fixed sleeve 50 .

其中,抓爪52包括爪身53和连接在抓身下端的爪头54,爪身53的内侧沿长度方向开设有容纳槽530,处于容纳槽530两侧的爪身53的内侧壁上设置有用于与固定套管50的外壁贴合的弧形面531;爪身53的上端开设有轴孔532;爪头54的内侧壁上形成引导斜面540。引导斜面540优选为弧形引导斜面540。爪头54的宽度大于爪身53的宽度,在爪头54的上表面上处于爪身53的内侧部分形成固定平面541。更进一步的,固定平面541的内侧具有弧形缺口506,弧形缺口506能与吸头本体80的外壁贴合,当爪头54的固定平面541处于环形凸沿81下方时,弧形缺口506的设计利于爪头54紧贴吸头本体80的外壁。The gripping claw 52 includes a claw body 53 and a claw head 54 connected to the lower end of the gripping body. The inner side of the claw body 53 is provided with an accommodating groove 530 along the length direction. A shaft hole 532 is formed on the upper end of the claw body 53 ; a guide slope 540 is formed on the inner side wall of the claw head 54 . The guide slope 540 is preferably an arc guide slope 540 . The width of the claw head 54 is larger than the width of the claw body 53 , and a fixed plane 541 is formed on the upper surface of the claw head 54 and the inner part of the claw body 53 . Further, the inner side of the fixing plane 541 has an arc-shaped notch 506, and the arc-shaped notch 506 can fit with the outer wall of the suction head body 80. When the fixing plane 541 of the claw head 54 is below the annular convex edge 81, the arc-shaped notch 506 The design facilitates the claw head 54 to be close to the outer wall of the suction head body 80 .

其中,吸头8包括吸头本体80以及设置在吸头本体80上端的环形凸沿81,抓爪组件51抓取吸头8后,环形凸沿81卡设在固定平面541上,从而使吸头8能够牢固卡抓在抓爪52上。The suction head 8 includes a suction head body 80 and an annular convex edge 81 disposed at the upper end of the suction head body 80. After the gripper assembly 51 grabs the suction head 8, the annular convex edge 81 is clamped on the fixed plane 541, so that the suction The head 8 can be firmly gripped on the gripper 52 .

其中,固定套管50外壁上由上至下依次设置有转动连接块501和弹簧安装块502,转动连接块501上设置有用于转动连接爪身53上端的连接轴504;拉紧弹簧503的一端与弹簧安装块502连接,另一端与容纳槽530的内壁连接。Among them, the outer wall of the fixed sleeve 50 is provided with a rotating connecting block 501 and a spring mounting block 502 in order from top to bottom, and the rotating connecting block 501 is provided with a connecting shaft 504 for rotating the upper end of the connecting claw body 53; It is connected with the spring mounting block 502 , and the other end is connected with the inner wall of the accommodating groove 530 .

弹簧拉紧对抓爪52具有向内的拉力,使抓爪52在无外力作用时会向中间收拢,爪身53通过弧形面531紧贴固定套管50外壁,爪头54上端的固定平面541保持水平,且两爪头54之间的距离小于环形凸沿81的外径,从而保证两个固定平面541处于环形凸沿81底面时能将吸头8抓牢。The spring tension has an inward pulling force on the gripping claw 52, so that the gripping claw 52 will be retracted to the middle when there is no external force. 541 is kept horizontal, and the distance between the two claw heads 54 is smaller than the outer diameter of the annular convex edge 81 , so as to ensure that the two fixing planes 541 can hold the suction head 8 firmly when the two fixing planes 541 are on the bottom surface of the annular convex edge 81 .

抓爪组件51的工作原理为:当通过X轴运动组件2和Y轴运动组件3将抓爪组件51移动到指定位置的吸头8上方后,Z轴运动组件4带动抓爪组件51、固定套管50向下移动;爪头54内侧的引导斜面540与吸头8上端的环形凸沿81的外壁接触,随着抓爪52向下运动,在引导斜面540的配合下,爪头54边向下运动边向外扩张(抓爪52的爪身53绕转动连接块501向外转动),如图8;直至爪头54越过环形凸沿81到达环形凸沿81下方,由于弹簧拉紧对抓爪52具有向内的拉力,使爪身53绕转动连接块501向内转动,爪头54也向内转动,恢复到初始位置,如图9,爪头54上端的固定平面541保持水平,并托住吸头8的环形凸沿81,爪头54的内侧压紧吸头本体80,从而使吸头8牢固的固定在抓爪组件51上;与此同时,固定套管50下端的锥体管段500配合插入到吸头8内,从而使固定套管50上端的移液吸管6与吸头8连通,再将吸头8移动至相应工作位置后,可通过吸头8吸取相关液体。The working principle of the gripper assembly 51 is as follows: after the gripper assembly 51 is moved above the suction head 8 at the designated position through the X-axis motion assembly 2 and the Y-axis motion assembly 3, the Z-axis motion assembly 4 drives the gripper assembly 51 to fix the gripper assembly 51. The sleeve 50 moves downward; the guiding inclined surface 540 on the inner side of the claw head 54 contacts the outer wall of the annular convex edge 81 on the upper end of the suction head 8. With the downward movement of the grabbing claw 52, under the cooperation of the guiding inclined surface 540, the claw head 54 edge The downward moving edge expands outward (the claw body 53 of the grasping claw 52 rotates outward around the rotating connecting block 501), as shown in Figure 8; The gripping claw 52 has an inward pulling force, so that the claw body 53 rotates inwardly around the rotating connecting block 501, and the claw head 54 also rotates inwardly and returns to the original position. And hold the annular convex edge 81 of the suction head 8, the inner side of the claw head 54 presses the suction head body 80, so that the suction head 8 is firmly fixed on the claw assembly 51; The body tube section 500 is inserted into the suction head 8, so that the pipette 6 at the upper end of the fixed sleeve 50 is communicated with the suction head 8. After moving the suction head 8 to the corresponding working position, the relevant liquid can be sucked through the suction head 8.

本实施例中,套取吸头8时,只需要对吸头8施加轻微的向下的压力即可牢固抓取吸头8,能避免因向下压力过大而使吸头8或是吸头盒7变形或损坏;套取过程中,移液吸管6不会与吸头8直接接触,能防止损坏移液吸管6(尤其是在移液吸管6上还连接有针头时)。In this embodiment, when the suction head 8 is sheathed, it is only necessary to apply a slight downward pressure to the suction head 8 to firmly grasp the suction head 8, which can avoid the suction head 8 or the suction head 8 caused by excessive downward pressure. The head box 7 is deformed or damaged; during the extraction process, the pipette 6 will not be in direct contact with the pipette tip 8, which can prevent damage to the pipette 6 (especially when a needle is connected to the pipette 6).

另外,可以理解的是,本优选的实施例中,吸头8上设置有环形凸沿81,能具有好的套取效果。而在当吸头8上不设置环形凸沿81时也能实现对吸头8的抓取,此时只需要满足爪头54收拢时,两个爪头54之间的距离小于吸头8的直径即可。In addition, it can be understood that, in this preferred embodiment, the suction head 8 is provided with an annular convex edge 81, which can have a good effect of pulling. However, the suction head 8 can also be grasped when the annular convex edge 81 is not provided on the suction head 8. At this time, it is only necessary to satisfy the requirement that when the claw heads 54 are closed, the distance between the two claw heads 54 is smaller than that of the suction head 8. diameter.

在进一步的实施例中,安装槽11的外周设置有四个用于固定放置在安装槽11内的吸头盒7的固定块12。固定块12的内壁上开设有弹片槽13,弹片槽13内设置有弧形弹片14。弧形弹片14的外表面上设置有定位顶球15,弧形弹片14的内表面上设置有压簧16;吸头盒7的外壁上开设有供定位顶球15配合插入的定位孔71。压簧16对弧形弹片14具有向外的顶压作用。吸头盒7上开设有若干用于存放吸头8的吸头孔7070.In a further embodiment, the outer periphery of the installation groove 11 is provided with four fixing blocks 12 for fixing the tip box 7 placed in the installation groove 11 . The inner wall of the fixing block 12 is provided with an elastic sheet groove 13 , and an arc-shaped elastic sheet 14 is arranged in the elastic sheet groove 13 . A positioning ball 15 is arranged on the outer surface of the arc-shaped elastic sheet 14, and a compression spring 16 is arranged on the inner surface of the arc-shaped elastic sheet 14; The compression spring 16 has an outward pressing effect on the arc-shaped elastic piece 14 . The tip box 7 is provided with a number of tip holes 7070 for storing the tip 8.

4个固定块12两两对称设置在安装槽11的四条边上,吸头盒7向下插入安装槽11内,向外侧挤压弧形弹片14,插入到位;弧形弹片14和压簧16为定位顶球15提供顶压力,四个定位顶球15配合插入的4个定位孔71内,从而使吸头盒7能牢固设置在安装槽11内。The four fixing blocks 12 are symmetrically arranged on the four sides of the installation groove 11. The suction head box 7 is inserted into the installation groove 11 downward, and the arc-shaped elastic sheet 14 is squeezed outward and inserted in place; the arc-shaped elastic sheet 14 and the compression spring 16 In order to provide the top pressure for the positioning balls 15, the four positioning balls 15 are inserted into the four positioning holes 71, so that the suction head box 7 can be firmly installed in the installation groove 11.

尽管本发明的实施方案已公开如上,但其并不仅仅限于说明书和实施方式中所列运用,它完全可以被适用于各种适合本发明的领域,对于熟悉本领域的人员而言,可容易地实现另外的修改,因此在不背离权利要求及等同范围所限定的一般概念下,本发明并不限于特定的细节。Although the embodiment of the present invention has been disclosed as above, it is not limited to the application listed in the description and the embodiment, and it can be applied to various fields suitable for the present invention. For those skilled in the art, it can be easily Therefore, the invention is not limited to the specific details without departing from the general concept defined by the appended claims and the scope of equivalents.

Claims (10)

1.一种可自动套取吸头的移液器,其特征在于,包括:底板、设置在所述底板上的三维运动机构、设置在所述三维运动机构上的吸头抓取机构、设置在所述吸头抓取机构上的移液吸管以及设置在所述底板上的用于放置所述吸头盒的安装槽;1. A pipette that can automatically cover a suction head, comprising: a base plate, a three-dimensional movement mechanism arranged on the base plate, a suction head grabbing mechanism arranged on the three-dimensional movement mechanism, a a pipette on the suction head grabbing mechanism and a mounting groove on the bottom plate for placing the suction head box; 所述三维运动机构用于带动所述吸头抓取机构进行三维移动;The three-dimensional motion mechanism is used to drive the suction head grasping mechanism to move three-dimensionally; 所述吸头抓取机构包括固定套管以及设置在所述固定套管上的抓爪组件,所述移液吸管与所述固定套管的上端连通,所述抓爪组件用于抓取所述吸头盒中的指定位置上的吸头,所述固定套管的下端用于与所述抓爪组件抓取的吸头连通。The suction head grasping mechanism includes a fixed sleeve and a grasping claw assembly arranged on the fixed sleeve, the pipette is communicated with the upper end of the fixed sleeve, and the grasping claw assembly is used for grasping the The suction head at the designated position in the suction head box, and the lower end of the fixed sleeve is used to communicate with the suction head grasped by the gripper assembly. 2.根据权利要求1所述的可自动套取吸头的移液器,其特征在于,所述三维运动机构包括设置在所述底板上的X轴运动组件、设置在所述X轴运动组件上的Y轴运动组件以及设置在所述Y轴运动组件上的Z轴运动组件;2 . The pipette capable of automatically covering a tip according to claim 1 , wherein the three-dimensional motion mechanism comprises an X-axis motion component arranged on the base plate, an X-axis motion component provided on the X-axis motion component. 3 . The Y-axis motion assembly on the upper and the Z-axis motion assembly arranged on the Y-axis motion assembly; 所述Z轴运动组件包括设置在所述Y轴运动组件上的Z轴安装板、设置在所述Z轴安装板上的Z轴电机、与所述Z轴电机驱动连接的Z轴丝杆以及与所述Z轴丝杆螺纹配合的Z轴滑套;The Z-axis motion assembly includes a Z-axis mounting plate disposed on the Y-axis motion assembly, a Z-axis motor disposed on the Z-axis mounting plate, a Z-axis screw drivingly connected to the Z-axis motor, and A Z-axis sliding sleeve matched with the Z-axis screw thread; 所述吸头抓取机构通过连接板固接在所述Z轴滑套上。The suction head grabbing mechanism is fixed on the Z-axis sliding sleeve through a connecting plate. 3.根据权利要求2所述的可自动套取吸头的移液器,其特征在于,所述底板上设置有安装支架,所述X轴运动组件包括设置在所述安装支架上的X轴电机、与所述X轴电机驱动连接的X轴丝杆以及套设在所述X轴丝杆上且与所述X轴丝杆螺纹配合的X轴滑块;3 . The pipette capable of automatically covering a tip according to claim 2 , wherein a mounting bracket is provided on the bottom plate, and the X-axis motion component comprises an X-axis arranged on the mounting bracket. 4 . a motor, an X-axis screw drivingly connected to the X-axis motor, and an X-axis slider sleeved on the X-axis screw and threadedly matched with the X-axis screw; 所述Y轴运动组件包括设置在所述X轴滑块上的Y轴安装板、设置在所述Y轴安装板上的Y轴电机、与所述Y轴电机驱动连接的Y轴丝杆以及套设在所述Y轴丝杆上且与所述Y轴丝杆螺纹配合的Y轴滑块;The Y-axis motion assembly includes a Y-axis mounting plate disposed on the X-axis slider, a Y-axis motor disposed on the Y-axis mounting plate, a Y-axis screw drivingly connected to the Y-axis motor, and a Y-axis slider sleeved on the Y-axis screw and threadedly matched with the Y-axis screw; 所述Z轴运动组件的Z轴安装板设置在所述Y轴滑块上。The Z-axis mounting plate of the Z-axis motion component is arranged on the Y-axis slider. 4.根据权利要求2所述的可自动套取吸头的移液器,其特征在于,所述固定套管的下端连接有锥体管段,所述锥体管段用于插入所述抓爪组件抓取的吸头内。4 . The pipette capable of automatically covering a tip according to claim 2 , wherein the lower end of the fixed sleeve is connected with a cone pipe section, and the cone pipe section is used for inserting the gripper assembly. 5 . Grab inside the tip. 5.根据权利要求1所述的可自动套取吸头的移液器,其特征在于,所述抓爪组件包括对称设置在所述固定套管外壁上的2个抓爪或是两两对称设置所述固定套管外壁上的4个抓爪;5 . The pipette capable of automatically sheathing a tip according to claim 1 , wherein the gripper assembly comprises two grippers symmetrically arranged on the outer wall of the fixed sleeve or symmetrical in two. 6 . Set 4 grippers on the outer wall of the fixed sleeve; 所述抓爪的上端与所述固定套管的外壁可转动连接,所述抓爪的中部与所述固定套管外壁之间连接有拉紧弹簧,所述抓爪的下端内侧具有引导斜面,所述引导斜面与所述吸头接触而受力时所述抓爪的下端向外旋转。The upper end of the gripping claw is rotatably connected with the outer wall of the fixing sleeve, a tension spring is connected between the middle part of the gripping claw and the outer wall of the fixing sleeve, and the inner side of the lower end of the gripping claw has a guiding slope, The lower end of the gripper rotates outward when the guide slope is in contact with the suction head and is stressed. 6.根据权利要求5所述的可自动套取吸头的移液器,其特征在于,所述抓爪包括爪身和连接在所述抓身下端的爪头,所述爪身的内侧沿长度方向开设有容纳槽,处于所述容纳槽两侧的爪身的内侧壁上设置有用于与所述固定套管的外壁贴合的弧形面;6 . The pipette capable of automatically covering a tip according to claim 5 , wherein the gripping claw comprises a claw body and a claw head connected to the lower end of the gripping body, and the inner edge of the claw body is 5 . 7 . An accommodating groove is opened in the length direction, and the inner side walls of the claw bodies on both sides of the accommodating groove are provided with arc surfaces for fitting with the outer wall of the fixing sleeve; 所述爪身的上端开设有轴孔;The upper end of the claw body is provided with a shaft hole; 所述爪头的内侧壁上形成所述引导斜面,所述爪头的宽度大于爪身的宽度,在所述爪头的上表面上处于所述爪身的内侧部分形成固定平面。The guide slope is formed on the inner side wall of the claw head, the width of the claw head is larger than the width of the claw body, and a fixed plane is formed on the upper surface of the claw head on the inner side of the claw body. 7.根据权利要求6所述的可自动套取吸头的移液器,其特征在于,所述吸头包括吸头本体以及设置在所述吸头本体上端的环形凸沿,所述抓爪组件抓取吸头后,所述环形凸沿卡设在所述固定平面上。7 . The pipette capable of automatically covering a tip according to claim 6 , wherein the suction tip comprises a tip body and an annular convex edge disposed on the upper end of the tip body, and the gripper After the assembly grabs the suction head, the annular convex edge is clamped on the fixed plane. 8.根据权利要求7所述的可自动套取吸头的移液器,其特征在于,所述固定套管外壁上由上至下依次设置有转动连接块和弹簧安装块,所述转动连接块上设置有用于转动连接所述爪身上端的连接轴;8 . The pipette capable of automatically covering a tip according to claim 7 , wherein a rotating connection block and a spring mounting block are sequentially arranged on the outer wall of the fixed sleeve from top to bottom, and the rotating connection The block is provided with a connecting shaft for rotatably connecting the upper end of the claw body; 所述拉紧弹簧的一端与所述弹簧安装块连接,另一端与所述容纳槽的内壁连接。One end of the tension spring is connected with the spring mounting block, and the other end is connected with the inner wall of the accommodating groove. 9.根据权利要求1所述的可自动套取吸头的移液器,其特征在于,所述安装槽的外周设置有四个用于固定放置在所述安装槽内的吸头盒的固定块;9 . The pipette capable of automatically sheathing a pipette according to claim 1 , wherein the outer periphery of the installation groove is provided with four fixing pipettes for fixing the pipette box placed in the installation groove. 10 . piece; 所述固定块的内壁上开设有弹片槽,所述弹片槽内设置有弧形弹片。The inner wall of the fixing block is provided with an elastic sheet groove, and an arc-shaped elastic sheet is arranged in the elastic sheet groove. 10.根据权利要求9所述的可自动套取吸头的移液器,其特征在于,所述弧形弹片的外表面上设置有定位顶球,所述弧形弹片的内表面上设置有压簧;10 . The pipette capable of automatically covering a tip according to claim 9 , wherein a positioning ball is provided on the outer surface of the arc-shaped elastic piece, and a positioning ball is provided on the inner surface of the arc-shaped elastic piece. 11 . compression spring; 所述吸头盒的外壁上开设有供所述定位顶球配合插入的定位孔。The outer wall of the suction head box is provided with a positioning hole for the matching insertion of the positioning ball.
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