CN111229349B - Pipette capable of automatically sleeving suction head - Google Patents
Pipette capable of automatically sleeving suction head Download PDFInfo
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- CN111229349B CN111229349B CN202010184398.4A CN202010184398A CN111229349B CN 111229349 B CN111229349 B CN 111229349B CN 202010184398 A CN202010184398 A CN 202010184398A CN 111229349 B CN111229349 B CN 111229349B
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- suction
- fixed sleeve
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- 230000007246 mechanism Effects 0.000 claims abstract description 49
- 239000007788 liquid Substances 0.000 claims abstract description 16
- 238000012546 transfer Methods 0.000 claims abstract description 6
- 210000000078 claw Anatomy 0.000 claims description 32
- 238000009434 installation Methods 0.000 claims description 3
- 238000004891 communication Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 230000006978 adaptation Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
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- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Manipulator (AREA)
Abstract
The invention discloses a pipette capable of automatically sleeving a suction head, which comprises: the device comprises a bottom plate, a three-dimensional moving mechanism arranged on the bottom plate, a suction head grabbing mechanism arranged on the three-dimensional moving mechanism, a liquid transferring suction pipe arranged on the suction head grabbing mechanism and a mounting groove arranged on the bottom plate and used for placing a suction head box; the three-dimensional movement mechanism is used for driving the suction head grabbing mechanism to move in three dimensions; the suction head grabbing mechanism comprises a fixed sleeve and a gripper assembly arranged on the fixed sleeve, the liquid transferring suction pipe is communicated with the upper end of the fixed sleeve, the gripper assembly is used for grabbing suction heads at designated positions in the suction head box, and the lower end of the fixed sleeve is used for being communicated with the suction heads grabbed by the gripper assembly. The three-dimensional motion mechanism drives the suction head grabbing mechanism to move in three dimensions, so that the automatic suction head sleeving function of the liquid transfer suction pipe can be realized, the stability of sleeving suction heads can be ensured, and meanwhile, the suction heads and the liquid transfer suction pipe can be well protected.
Description
Technical Field
The invention relates to the field of pipetting equipment, in particular to a pipette capable of automatically sleeving a suction head.
Background
Micropipette tips (or tips) are commonly found in biological and pharmaceutical laboratories and are the most commonly used consumables in experiments. In the prior art, there are a large number of manually operated pipettes, but the pipetting efficiency is low, time and labor are wasted, so that some automatic pipetting devices are also appeared, and the pipetting assembly (including a pipette and an external liquid path unit connected with the pipette, and possibly a needle also connected with some pipettes) is loaded through a two-dimensional or three-dimensional movement mechanism, so that the pipetting assembly is driven to move to a designated position, the pipette is used for taking the pipette, and then related pipetting work is performed. After the pipette tip is taken, the pipette tip and the pipette are required to be firmly connected, and the pipette tip is prevented from falling off in the pipetting process, so that the pipette tip can be generally realized through the following scheme, and one mode is as follows: the size of the tail end of the pipette is designed to be smaller than that of the tip, the pipette is extruded into the tip through pressure, and at the moment, larger acting force is required to be applied to the tip through the pipette when the tip is sleeved, so that the tip is ensured to be firmly sleeved on the pipette; however, the pipette tip and the tip cassette in which the pipette tip is mounted are easily deformed or damaged, and the pipette is easily damaged. Another way is to arrange a related adapting structure on the tip and/or the pipette, and the connection between the tip and the pipette is realized through the adapting structure; however, this has the disadvantage that the adaptation is generally complex and in addition requires a certain rotation of the pipette relative to the tip for a firm connection, which increases the complexity of the movement mechanism. Therefore, a more reliable solution is now needed.
Disclosure of Invention
The technical problem to be solved by the invention is to provide a pipette capable of automatically sleeving a suction head aiming at the defects in the prior art.
In order to solve the technical problems, the invention adopts the following technical scheme: a pipette capable of automatically sleeving a suction head, comprising: the device comprises a bottom plate, a three-dimensional moving mechanism arranged on the bottom plate, a suction head grabbing mechanism arranged on the three-dimensional moving mechanism, a liquid transferring suction pipe arranged on the suction head grabbing mechanism and a mounting groove arranged on the bottom plate and used for placing the suction head box;
The three-dimensional movement mechanism is used for driving the suction head grabbing mechanism to move in three dimensions;
The suction head grabbing mechanism comprises a fixed sleeve and a gripper assembly arranged on the fixed sleeve, the liquid transferring suction pipe is communicated with the upper end of the fixed sleeve, the gripper assembly is used for grabbing suction heads at designated positions in the suction head box, and the lower end of the fixed sleeve is used for being communicated with the suction heads grabbed by the gripper assembly.
Preferably, the three-dimensional movement mechanism comprises an X-axis movement assembly arranged on the bottom plate, a Y-axis movement assembly arranged on the X-axis movement assembly and a Z-axis movement assembly arranged on the Y-axis movement assembly;
The Z-axis motion assembly comprises a Z-axis mounting plate arranged on the Y-axis motion assembly, a Z-axis motor arranged on the Z-axis mounting plate, a Z-axis screw rod in driving connection with the Z-axis motor and a Z-axis sliding sleeve in threaded fit with the Z-axis screw rod;
the suction head grabbing mechanism is fixedly connected to the Z-axis sliding sleeve through a connecting plate.
Preferably, the bottom plate is provided with a mounting bracket, and the X-axis movement assembly comprises an X-axis motor arranged on the mounting bracket, an X-axis screw rod in driving connection with the X-axis motor, and an X-axis sliding block sleeved on the X-axis screw rod and in threaded fit with the X-axis screw rod;
The Y-axis motion assembly comprises a Y-axis mounting plate arranged on the X-axis sliding block, a Y-axis motor arranged on the Y-axis mounting plate, a Y-axis screw rod in driving connection with the Y-axis motor, and a Y-axis sliding block sleeved on the Y-axis screw rod and in threaded fit with the Y-axis screw rod;
and a Z-axis mounting plate of the Z-axis movement assembly is arranged on the Y-axis sliding block.
Preferably, a cone pipe section is connected to the lower end of the fixed sleeve, and the cone pipe section is used for being inserted into the suction head grabbed by the gripper assembly.
Preferably, the gripper assembly comprises 2 grippers symmetrically arranged on the outer wall of the fixed sleeve or 4 grippers symmetrically arranged on the outer wall of the fixed sleeve in pairs;
The upper end of the gripper is rotatably connected with the outer wall of the fixed sleeve, a tensioning spring is connected between the middle part of the gripper and the outer wall of the fixed sleeve, the inner side of the lower end of the gripper is provided with a guide inclined plane, and the lower end of the gripper rotates outwards when the guide inclined plane contacts with the suction head to bear force.
Preferably, the gripper comprises a gripper body and a gripper head connected to the lower end of the gripper body, wherein an accommodating groove is formed in the inner side of the gripper body along the length direction, and an arc-shaped surface for being attached to the outer wall of the fixed sleeve is arranged on the inner side wall of the gripper body at two sides of the accommodating groove;
the upper end of the claw body is provided with a shaft hole;
The guide inclined plane is formed on the inner side wall of the claw head, the width of the claw head is larger than that of the claw body, and a fixing plane is formed on the inner side part of the claw body on the upper surface of the claw head.
Preferably, the suction head comprises a suction head body and an annular convex edge arranged at the upper end of the suction head body, and the annular convex edge is clamped on the fixing plane after the suction head is grabbed by the gripper assembly.
Preferably, a rotary connecting block and a spring mounting block are sequentially arranged on the outer wall of the fixed sleeve from top to bottom, and a connecting shaft for rotationally connecting the upper ends of the claw bodies is arranged on the rotary connecting block;
One end of the tensioning spring is connected with the spring mounting block, and the other end of the tensioning spring is connected with the inner wall of the accommodating groove.
Preferably, four fixing blocks for fixing the suction head box placed in the mounting groove are arranged on the periphery of the mounting groove;
the inner wall of the fixed block is provided with an elastic sheet groove, and an arc-shaped elastic sheet is arranged in the elastic sheet groove.
Preferably, a positioning top ball is arranged on the outer surface of the arc-shaped elastic piece, and a pressure spring is arranged on the inner surface of the arc-shaped elastic piece;
And a positioning hole for the positioning top ball to be inserted in a matched manner is formed in the outer wall of the suction head box.
The beneficial effects of the invention are as follows: according to the pipette capable of automatically sleeving the suction head, the three-dimensional motion mechanism drives the suction head grabbing mechanism to move in three dimensions, so that the function of automatically sleeving the suction head by the pipette can be realized, the stability of sleeving the suction head can be ensured, and meanwhile, the suction head and the pipette can be well protected;
when the suction head grabbing mechanism is sleeved with the suction head, the suction head can be firmly grabbed by only applying slight downward pressure to the suction head, so that the suction head or the suction head box is prevented from being deformed or damaged due to the excessive downward pressure; in the process of sleeving, the liquid-transferring suction pipe can not be in direct contact with the suction head, and the liquid-transferring suction pipe can be prevented from being damaged.
Drawings
FIG. 1 is a schematic view of a pipette capable of automatically sleeving a suction head according to the present invention;
FIG. 2 is a schematic view of a pipette with automatic tip extraction according to another view of the present invention;
FIG. 3 is a schematic view of the suction head gripping mechanism of the present invention;
FIG. 4 is a schematic view of the structure of the gripper of the present invention;
FIG. 5 is a schematic view of the structure of the fixing sleeve of the present invention;
FIG. 6 is a schematic view of the structure of the invention in which the retaining sleeve is engaged with the grippers;
FIG. 7 is a schematic view of the structure of the suction head of the present invention;
FIG. 8 is a schematic view showing a state in which the suction head gripping mechanism grips the suction head of the present invention;
FIG. 9 is a schematic view showing another state in which the suction head gripping mechanism grips the suction head of the present invention;
FIG. 10 is a schematic view of the structure of the base plate of the present invention;
FIG. 11 is a schematic view of the structure of the tip box of the present invention;
FIG. 12 is a schematic view of the structure of the fixing block of the present invention;
fig. 13 is a schematic cross-sectional structure of the fixing block of the present invention.
Reference numerals illustrate:
1-a bottom plate; 10-mounting a bracket; 11-mounting groove; 12-a fixed block; 13-spring piece grooves; 14-an arc-shaped elastic sheet; 15-positioning a top ball; 16-a compression spring;
2-X axis movement assembly; 20-X axis motor; 21-X axis screw rod; 22-X axis sliding block; 23-X axis optocoupler; 24-X baffle;
A 3-Y axis motion assembly; 30-Y axis mounting plate; 31-Y axis motor; 32-Y axis screw rod; 33-Y axis slide block; 34-Y axis optocoupler; 35-Y baffle plates;
A 4-Z axis motion assembly; a 40-Z axis mounting plate; 41-Z axis motor; 42-Z axis screw rod; 43-Z axis sliding sleeve; 44-connecting plates; 45-Z axis optocoupler; 46-Z baffle;
5-a suction head grabbing mechanism; 50-fixing the sleeve; 51—a gripper assembly; 52-grippers; 53-claw body; 54-claw heads; 500-cone pipe sections; 501-rotating a connecting block; 502—a spring mounting block; 503—tensioning the spring; 504—a connecting shaft; 505-communication holes; 506-arc notch; 530—a receiving slot; 531-arc surface; 532-shaft hole; 540—a guide ramp; 541-a fixed plane;
6-a liquid transfer pipette;
7-a suction head box; 70-a tip well; 71-positioning holes;
8-suction head; 80-a suction head body; 81-annular flange.
Detailed Description
The present invention is described in further detail below with reference to examples to enable those skilled in the art to practice the same by referring to the description.
It will be understood that terms, such as "having," "including," and "comprising," as used herein, do not preclude the presence or addition of one or more other elements or groups thereof.
As shown in fig. 1, a pipette capable of automatically sleeving a pipette tip 8 according to the present embodiment includes: the three-dimensional suction head box comprises a bottom plate 1, a three-dimensional movement mechanism arranged on the bottom plate 1, a suction head grabbing mechanism 5 arranged on the three-dimensional movement mechanism, a liquid transfer suction pipe 6 arranged on the suction head grabbing mechanism 5 and a mounting groove 11 arranged on the bottom plate 1 and used for placing the suction head box 7;
The three-dimensional movement mechanism is used for driving the suction head grabbing mechanism 5 to move in three dimensions;
The suction head grabbing mechanism 5 comprises a fixed sleeve 50 and a gripper assembly 51 arranged on the fixed sleeve 50, the liquid transferring suction pipe 6 is communicated with the upper end of the fixed sleeve 50, the gripper assembly 51 is used for grabbing the suction head 8 at a designated position in the suction head box 7, and the lower end of the fixed sleeve 50 is used for communicating with the suction head 8 grabbed by the gripper assembly 51.
In the invention, the pipette 6 is communicated with the upper end of the fixed sleeve 50, the three-dimensional movement mechanism drives the fixed sleeve 50, the gripper assembly 51 thereon and the pipette 6 to move together in three dimensions so as to move to the position above the pipette tip 8 at the designated position in the pipette tip box 7, then move downwards together, the pipette tip 8 is grabbed by the gripper assembly 51, and at the moment, the lower end of the fixed sleeve 50 is communicated with the grabbed pipette tip 8, so that the pipette tip 6 is communicated with the pipette tip 8, and then the pipette tip can move to other positions to perform relevant pipetting operations. In the present invention, the conventional pipetting device is not used to grasp the pipette tip 8 by the pipette tip 6 itself, but a special gripper assembly 51 is used to grasp the pipette tip 8 and then hold and put the pipette tip 6 in communication with the pipette tip 8. The stability of sleeving the suction head 8 can be ensured, and the suction head 8 and the pipette 6 can be well protected. It will be appreciated that the tip of the pipette 6 may also be connected to a needle. In addition, the upper end of the pipette 6 is connected to an external necessary conventional liquid path system (not specifically described in the present invention) to realize a liquid sucking function. The foregoing is a basic idea of the invention and the following provides further detailed embodiments on the basis thereof.
In a preferred embodiment, referring to fig. 1 and 2, the three-dimensional movement mechanism includes an X-axis movement assembly 2 provided on a base plate 1, a Y-axis movement assembly 3 provided on the X-axis movement assembly 2, and a Z-axis movement assembly 4 provided on the Y-axis movement assembly 3; the Z-axis motion assembly 4 comprises a Z-axis mounting plate 40 arranged on the Y-axis motion assembly 3, a Z-axis motor 41 arranged on the Z-axis mounting plate 40, a Z-axis screw rod 42 in driving connection with the Z-axis motor 41 and a Z-axis sliding sleeve 43 in threaded fit with the Z-axis screw rod 42; the suction head grabbing mechanism 5 is fixedly connected to the Z-axis sliding sleeve 43 through a connecting plate 44. The Z-axis screw rod 42 is driven to rotate by the Z-axis motor 41, so that the Z-axis sliding sleeve 43 in threaded fit with the Z-axis screw rod 42 moves up and down.
The base plate 1 is provided with a mounting bracket 10, and the X-axis motion assembly 2 comprises an X-axis motor 20 arranged on the mounting bracket 10, an X-axis screw rod 21 in driving connection with the X-axis motor 20 and an X-axis sliding block 22 sleeved on the X-axis screw rod 21 and in threaded fit with the X-axis screw rod 21;
The Y-axis motion assembly 3 comprises a Y-axis mounting plate 30 arranged on the X-axis sliding block 22, a Y-axis motor 31 arranged on the Y-axis mounting plate 30, a Y-axis screw rod 32 in driving connection with the Y-axis motor 31 and a Y-axis sliding block 33 sleeved on the Y-axis screw rod 32 and in threaded fit with the Y-axis screw rod 32; the Z-axis mounting plate 40 of the Z-axis moving assembly 4 is provided on the Y-axis slider 33.
In this embodiment, three-dimensional driving is realized by a motor screw mechanism to move the gripper assembly 51 and the pipette 6 to a specified position.
In a further embodiment, position detection mechanisms are arranged in three directions to achieve zero position positioning in three directions X, Y, Z, and the position detection mechanisms comprise groove-type optocouplers and baffle plates. Specifically, an X-axis optocoupler 23 is arranged on the mounting bracket 10, and an X-baffle 24 matched with the X-axis optocoupler 23 is arranged on the X-axis sliding block 22; the Y-axis mounting plate 30 is provided with a Y-axis optocoupler 34, and the Y-axis sliding block 33 is provided with a Y-baffle 35 matched with the Y-axis optocoupler 34; the Z-axis installation plate 40 is provided with a Z-axis optical coupler 45, and the Z-axis sliding sleeve 43 is provided with a Z-baffle 46 matched with the Z-axis optical coupler 45.
Further, a cone pipe section 500 is connected to the lower end of the fixed sleeve 50, and the cone pipe section 500 is used for being inserted into the suction head 8 grabbed by the gripper assembly 51. The gripper assembly 51 includes 2 grippers 52 symmetrically disposed on the outer wall of the fixed sleeve 50 or 4 grippers 52 symmetrically disposed on the outer wall of the fixed sleeve 50 in pairs; in this embodiment, 2; the upper end of the gripper 52 is rotatably connected with the outer wall of the fixed sleeve 50, a tensioning spring 503 is connected between the middle part of the gripper 52 and the outer wall of the fixed sleeve 50, a guiding inclined plane 540 is arranged on the inner side of the lower end of the gripper 52, and the guiding inclined plane 540 contacts with the suction head 8 so that the lower end of the gripper 52 rotates outwards when being stressed. The fixed sleeve 50 is provided with a communication hole 505.
The gripper 52 comprises a gripper body 53 and a gripper head 54 connected to the lower end of the gripper body, wherein an accommodating groove 530 is formed in the inner side of the gripper body 53 along the length direction, and arc-shaped surfaces 531 for being attached to the outer wall of the fixed sleeve 50 are formed on the inner side walls of the gripper body 53 at two sides of the accommodating groove 530; the upper end of the claw body 53 is provided with a shaft hole 532; a guide ramp 540 is formed on the inside wall of the jaw 54. The guide ramp 540 is preferably an arcuate guide ramp 540. The width of the jaw 54 is larger than the width of the jaw body 53, and a fixing plane 541 is formed on an upper surface of the jaw 54 at an inner side portion of the jaw body 53. Furthermore, the inner side of the fixing plane 541 has an arc-shaped notch 506, the arc-shaped notch 506 can be attached to the outer wall of the suction head body 80, and when the fixing plane 541 of the claw 54 is located below the annular flange 81, the design of the arc-shaped notch 506 is beneficial for the claw 54 to be attached to the outer wall of the suction head body 80.
Wherein, suction head 8 includes suction head body 80 and sets up the annular protruding edge 81 at suction head body 80 upper end, and after the gripper assembly 51 snatched suction head 8, annular protruding edge 81 card was established on fixed plane 541 to make suction head 8 can firmly block and grab on gripper 52.
Wherein, the outer wall of the fixed sleeve 50 is sequentially provided with a rotary connecting block 501 and a spring mounting block 502 from top to bottom, and the rotary connecting block 501 is provided with a connecting shaft 504 for rotationally connecting the upper end of the claw body 53; one end of the tension spring 503 is connected to the spring mounting block 502, and the other end is connected to the inner wall of the receiving groove 530.
The spring tensioning has inward tension to the grippers 52, so that the grippers 52 can be folded towards the middle when no external force acts, the gripper body 53 is tightly attached to the outer wall of the fixed sleeve 50 through the arc-shaped surface 531, the fixed plane 541 at the upper end of the gripper head 54 is kept horizontal, and the distance between the two gripper heads 54 is smaller than the outer diameter of the annular convex edge 81, so that the suction head 8 can be firmly gripped when the two fixed planes 541 are positioned on the bottom surface of the annular convex edge 81.
The gripper assembly 51 operates on the principle that: after the gripper assembly 51 is moved to the position above the suction head 8 at the designated position through the X-axis movement assembly 2 and the Y-axis movement assembly 3, the Z-axis movement assembly 4 drives the gripper assembly 51 and the fixed sleeve 50 to move downwards; the guiding inclined surface 540 on the inner side of the claw 54 contacts with the outer wall of the annular convex edge 81 on the upper end of the suction head 8, and as the claw 52 moves downwards, the claw 54 expands outwards while moving downwards (the claw body 53 of the claw 52 rotates outwards around the rotating connecting block 501) under the cooperation of the guiding inclined surface 540, as shown in fig. 8; until the claw 54 passes over the annular convex edge 81 and reaches the lower part of the annular convex edge 81, the claw 52 is pulled inwards by the spring tension, so that the claw body 53 rotates inwards around the rotation connecting block 501, the claw 54 also rotates inwards to restore to the initial position, as shown in fig. 9, the fixing plane 541 at the upper end of the claw 54 keeps horizontal and holds the annular convex edge 81 of the suction head 8, and the inner side of the claw 54 presses the suction head body 80, so that the suction head 8 is firmly fixed on the claw assembly 51; at the same time, the cone pipe section 500 at the lower end of the fixed sleeve 50 is inserted into the suction head 8 in a matched manner, so that the liquid transfer pipette 6 at the upper end of the fixed sleeve 50 is communicated with the suction head 8, and after the suction head 8 is moved to the corresponding working position, relevant liquid can be sucked through the suction head 8.
In this embodiment, when the suction head 8 is sleeved, only a slight downward pressure is applied to the suction head 8 to firmly grasp the suction head 8, so that deformation or damage of the suction head 8 or the suction head box 7 caused by excessive downward pressure can be avoided; during the taking-in process, the pipette 6 does not come into direct contact with the suction head 8, and damage to the pipette 6 (especially when a needle is further attached to the pipette 6) can be prevented.
In addition, it will be appreciated that in the preferred embodiment, the suction head 8 is provided with an annular lip 81 which provides a good pick-up effect. The grabbing of the suction head 8 can be realized when the annular convex edge 81 is not arranged on the suction head 8, and the distance between the two claw heads 54 is smaller than the diameter of the suction head 8 only when the claw heads 54 are folded.
In a further embodiment, the outer circumference of the mounting groove 11 is provided with four fixing blocks 12 for fixing the tip box 7 placed in the mounting groove 11. The inner wall of the fixed block 12 is provided with a spring slot 13, and an arc spring 14 is arranged in the spring slot 13. The outer surface of the arc-shaped elastic sheet 14 is provided with a positioning top ball 15, and the inner surface of the arc-shaped elastic sheet 14 is provided with a pressure spring 16; the outer wall of the suction head box 7 is provided with a positioning hole 71 for the matching insertion of the positioning top ball 15. The compression spring 16 has an outward pressing effect on the arc-shaped spring piece 14. The tip box 7 is provided with a plurality of tip holes 7070 for storing the tips 8.
The 4 fixing blocks 12 are symmetrically arranged on four sides of the mounting groove 11 in pairs, the suction head box 7 is inserted into the mounting groove 11 downwards, the arc-shaped elastic sheet 14 is extruded outwards, and the suction head box is inserted into place; the arc-shaped elastic sheet 14 and the pressure spring 16 provide a jacking force for the positioning jacking balls 15, and the four positioning jacking balls 15 are matched and inserted into the 4 positioning holes 71, so that the suction head box 7 can be firmly arranged in the mounting groove 11.
Although embodiments of the present invention have been disclosed above, it is not limited to the use of the description and embodiments, it is well suited to various fields of use for the invention, and further modifications may be readily apparent to those skilled in the art, and accordingly, the invention is not limited to the particular details without departing from the general concepts defined in the claims and the equivalents thereof.
Claims (5)
1. A pipette capable of automatically sleeving a suction head, comprising: the device comprises a bottom plate, a three-dimensional moving mechanism arranged on the bottom plate, a suction head grabbing mechanism arranged on the three-dimensional moving mechanism, a liquid transferring suction pipe arranged on the suction head grabbing mechanism and a mounting groove arranged on the bottom plate and used for placing a suction head box;
The three-dimensional movement mechanism is used for driving the suction head grabbing mechanism to move in three dimensions;
The suction head grabbing mechanism comprises a fixed sleeve and a gripper assembly arranged on the fixed sleeve, the liquid transfer suction pipe is communicated with the upper end of the fixed sleeve, the gripper assembly is used for grabbing suction heads at designated positions in the suction head box, and the lower end of the fixed sleeve is communicated with the suction heads grabbed by the gripper assembly;
The lower end of the fixed sleeve is connected with a cone pipe section which is used for being inserted into the suction head grabbed by the grabbing component; the gripper assembly comprises 2 grippers symmetrically arranged on the outer wall of the fixed sleeve or 4 grippers symmetrically arranged on the outer wall of the fixed sleeve in pairs; the upper end of the gripper is rotatably connected with the outer wall of the fixed sleeve, a tensioning spring is connected between the middle part of the gripper and the outer wall of the fixed sleeve, the inner side of the lower end of the gripper is provided with a guide inclined plane, and the lower end of the gripper rotates outwards when the guide inclined plane contacts with the suction head to bear force;
The gripper comprises a gripper body and a gripper head connected to the lower end of the gripper body, wherein an accommodating groove is formed in the inner side of the gripper body along the length direction, and an arc-shaped surface which is used for being attached to the outer wall of the fixed sleeve is arranged on the inner side wall of the gripper body at two sides of the accommodating groove; the upper end of the claw body is provided with a shaft hole; the guide inclined plane is formed on the inner side wall of the claw head, the width of the claw head is larger than that of the claw body, and a fixed plane is formed on the inner side part of the claw body on the upper surface of the claw head;
The suction head comprises a suction head body and an annular convex edge arranged at the upper end of the suction head body, and the annular convex edge is clamped on the fixing plane after the suction head is grabbed by the grabbing component; the outer wall of the fixed sleeve is sequentially provided with a rotary connecting block and a spring mounting block from top to bottom, and the rotary connecting block is provided with a connecting shaft for rotationally connecting the upper ends of the claw bodies;
One end of the tensioning spring is connected with the spring mounting block, and the other end of the tensioning spring is connected with the inner wall of the accommodating groove.
2. The pipette capable of automatically sleeving a suction head according to claim 1, wherein the three-dimensional movement mechanism comprises an X-axis movement assembly arranged on the bottom plate, a Y-axis movement assembly arranged on the X-axis movement assembly and a Z-axis movement assembly arranged on the Y-axis movement assembly;
The Z-axis motion assembly comprises a Z-axis mounting plate arranged on the Y-axis motion assembly, a Z-axis motor arranged on the Z-axis mounting plate, a Z-axis screw rod in driving connection with the Z-axis motor and a Z-axis sliding sleeve in threaded fit with the Z-axis screw rod;
the suction head grabbing mechanism is fixedly connected to the Z-axis sliding sleeve through a connecting plate.
3. The pipette capable of automatically sleeving a suction head according to claim 2, wherein a mounting bracket is arranged on the bottom plate, and the X-axis movement assembly comprises an X-axis motor arranged on the mounting bracket, an X-axis screw rod in driving connection with the X-axis motor and an X-axis sliding block sleeved on the X-axis screw rod and in threaded fit with the X-axis screw rod;
The Y-axis motion assembly comprises a Y-axis mounting plate arranged on the X-axis sliding block, a Y-axis motor arranged on the Y-axis mounting plate, a Y-axis screw rod in driving connection with the Y-axis motor, and a Y-axis sliding block sleeved on the Y-axis screw rod and in threaded fit with the Y-axis screw rod;
and a Z-axis mounting plate of the Z-axis movement assembly is arranged on the Y-axis sliding block.
4. The pipette capable of automatically sleeving a suction head as recited in claim 1, wherein four fixing blocks for fixing a suction head box placed in the installation groove are arranged on the periphery of the installation groove;
the inner wall of the fixed block is provided with an elastic sheet groove, and an arc-shaped elastic sheet is arranged in the elastic sheet groove.
5. The pipette capable of automatically sleeving a suction head according to claim 4, wherein a positioning top ball is arranged on the outer surface of the arc-shaped elastic piece, and a pressure spring is arranged on the inner surface of the arc-shaped elastic piece;
And a positioning hole for the positioning top ball to be inserted in a matched manner is formed in the outer wall of the suction head box.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010184398.4A CN111229349B (en) | 2020-03-17 | 2020-03-17 | Pipette capable of automatically sleeving suction head |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010184398.4A CN111229349B (en) | 2020-03-17 | 2020-03-17 | Pipette capable of automatically sleeving suction head |
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| Publication Number | Publication Date |
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| CN111229349A CN111229349A (en) | 2020-06-05 |
| CN111229349B true CN111229349B (en) | 2024-04-26 |
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| CN202010184398.4A Active CN111229349B (en) | 2020-03-17 | 2020-03-17 | Pipette capable of automatically sleeving suction head |
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| CN112844507B (en) * | 2020-12-31 | 2022-10-25 | 广西机电职业技术学院 | Liquid-transfering suction head and equipment mechanism who moves liquid cover handle |
Citations (10)
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| CN209576727U (en) * | 2019-02-16 | 2019-11-05 | 江苏科百生物技术有限公司 | A kind of pipetting tip convenient for being clamped with pipettor |
| CN110646628A (en) * | 2019-09-30 | 2020-01-03 | 中国科学院苏州生物医学工程技术研究所 | Reaction cup grabbing and placing device for immunoassay analyzer |
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| US5906795A (en) * | 1996-04-08 | 1999-05-25 | Sanyo Electric Co., Ltd. | Pipetting apparatus |
| CN201510887U (en) * | 2009-05-14 | 2010-06-23 | 上海科华实验系统有限公司 | Liquid-transferring device with an automatic imbibition head removing mechanism |
| CN201729505U (en) * | 2010-07-13 | 2011-02-02 | 高要市金田电热有限公司 | Electric heating pipe grabbing device |
| CN204638221U (en) * | 2015-05-18 | 2015-09-16 | 杭州固拓生物科技有限公司 | Pipettor gun barrel and suction nozzle syndeton |
| CN206935403U (en) * | 2017-06-27 | 2018-01-30 | 复旦大学附属金山医院 | Magnetic-type liquid-transfering device |
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| CN109455342A (en) * | 2018-09-03 | 2019-03-12 | 常州市第三人民医院 | A kind of automatic mounted box equipment of suction pipette head |
| CN209205357U (en) * | 2018-12-14 | 2019-08-06 | 杭州华葵金配生物科技有限公司 | A kind of pipettor automatic clamping device |
| CN209576727U (en) * | 2019-02-16 | 2019-11-05 | 江苏科百生物技术有限公司 | A kind of pipetting tip convenient for being clamped with pipettor |
| CN110646628A (en) * | 2019-09-30 | 2020-01-03 | 中国科学院苏州生物医学工程技术研究所 | Reaction cup grabbing and placing device for immunoassay analyzer |
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| CN111229349A (en) | 2020-06-05 |
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