CN111228363A - Medicinal liquor for treating rheumatic joint and hyperosteogeny and preparation method thereof - Google Patents

Medicinal liquor for treating rheumatic joint and hyperosteogeny and preparation method thereof Download PDF

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CN111228363A
CN111228363A CN202010252124.4A CN202010252124A CN111228363A CN 111228363 A CN111228363 A CN 111228363A CN 202010252124 A CN202010252124 A CN 202010252124A CN 111228363 A CN111228363 A CN 111228363A
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parts
root
hyperosteogeny
medicinal liquor
treating rheumatic
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罗军
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486—Millettia
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The invention relates to a medicinal liquor for treating rheumatic joints and hyperosteogeny, which is prepared by soaking ten raw material medicines, such as safflower, radix aconiti agrestis, ligusticum wallichii, acanthopanax, caulis spatholobi, nux vomica, short-pedicel aconite root, white dragon beard, radix anisodus acutanguli, polygonum multiflorum, eucommia bark and the like, into high-alcohol wine. The invention has the beneficial effects that: the medicinal liquor is mainly used for treating rheumatic joints, cervical and lumbar disc herniation and hyperosteogeny through years of practice, improvement, perfection and clinical proof, and has the characteristics of quick curative effect, short treatment course, treatment of both symptoms and root causes, high cure rate and no toxic or side effect; the preparation method of the invention is simple and the administration is convenient.

Description

Medicinal liquor for treating rheumatic joint and hyperosteogeny and preparation method thereof
Technical Field
The invention belongs to the field of traditional Chinese medicines, and particularly relates to medicinal liquor for treating rheumatic joint and hyperosteogeny and a preparation method thereof.
Background
Rheumatoid arthritis (rheumatoid arthritis) is a common acute or chronic inflammation of connective tissue. Generally, the rheumatic arthritis is one of the main manifestations of rheumatic fever, and is clinically characterized by joint and muscle wandering soreness, red swelling and pain. Although the incidence of rheumatic fever has declined significantly in recent decades, atypical rheumatic fever and chronic rheumatic arthritis are not uncommon. Hyperosteogeny, also known as proliferative osteoarthropathy, refers to a chronic arthropathy resulting from the destruction of articular cartilage due to degeneration of joints. The method mainly comprises two steps: the basic etiology of the primary osteoarthropathy is the gradual aging and degeneration of a human body after the human body is mature, and the manifestation of the primary osteoarthropathy is in the aspect of osteoarthropathy; secondary osteoarthropathy refers to cartilage destruction, or a change in joint structure, due to some known cause, such as trauma, surgery or other obvious factor. The degeneration of the articular surface is caused by friction or imbalance of pressure. Rheumatic arthritis and hyperosteogeny belong to chronic diseases, the treatment effects of mechanical treatment and Chinese and western medicines are not obvious, and people always explore a better treatment scheme.
In view of this, the present application is presented.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides medicinal liquor for treating rheumatic joints and hyperosteogeny and a preparation method thereof.
The technical scheme adopted by the invention is as follows:
a medicated wine for treating rheumatic joint and hyperosteogeny comprises the following raw material medicines:
safflower, kusnezoff monkshood root, pseudo-ginseng, acanthopanax, suberect spatholobus stem, nux vomica, short-pedicel aconite root, szechuan lovage rhizome, white dragon beard, acutangular anisodus root, tuber fleeceflower root, eucommia bark and common monkshood mother root.
Further, the medicinal liquor comprises the following raw material medicines in parts by weight:
20-40 parts of safflower, 5-15 parts of kusnezoff monkshood root, 40-60 parts of pseudo-ginseng, 40-60 parts of acanthopanax, 40-60 parts of suberect spatholobus stem, 5-15 parts of nux vomica, 5-15 parts of short-pedicel aconite root, 15-25 parts of szechuan lovage rhizome, 15-25 parts of white dragon beard, 5-15 parts of acutangular anisodus root, 15-25 parts of tuber fleeceflower root, 15-25 parts of eucommia bark and 5-15 parts of common monkshood mother.
Further, the medicinal liquor comprises the following raw material medicines in parts by weight:
25-35 parts of safflower, 8-12 parts of kusnezoff monkshood root, 45-55 parts of pseudo-ginseng, 45-55 parts of acanthopanax, 45-55 parts of suberect spatholobus stem, 8-12 parts of nux vomica, 6-14 parts of short-pedicel aconite root, 18-22 parts of szechuan lovage rhizome, 18-22 parts of white dragon beard, 8-12 parts of acutangular anisodus root, 19-21 parts of tuber fleeceflower root, 18-22 parts of eucommia bark and 8-22 parts of common monkshood mother.
Further, the medicinal liquor comprises the following raw material medicines in parts by weight:
30 parts of safflower, 10 parts of kusnezoff monkshood root, 50 parts of pseudo-ginseng, 50 parts of acanthopanax, 50 parts of suberect spatholobus stem, 10 parts of nux vomica, 10 parts of short-pedicel aconite root, 20 parts of szechuan lovage rhizome, 20 parts of white dragon beard, 10 parts of acutangular anisodus root, 20 parts of tuber fleeceflower root, 20 parts of eucommia bark and 10 parts of common monkshood.
A method for preparing the medicinal liquor for treating the rheumatic joint and the hyperosteogeny comprises the following steps:
drying all the raw materials, soaking in wine for 5-9 days to obtain the medicated liquor for treating rheumatic arthritis and hyperosteogeny.
Further, the wine is corn wine, and the alcohol content of the wine is 50 degrees.
Further, all the raw material medicines are sterilized by flowing steam before being dried, and then are dried at the high temperature of 80-90 ℃ until the water content of the dried raw material medicines is less than or equal to 5 wt%.
Further, the soaking time is 7 days.
The taking method of the invention comprises the following steps: after meals, the medicinal liquor is drunk three times a day, and the money is 5 to two times each time. Contraindications are as follows: patients with hypertension and diabetes can not drink the tea.
The main raw material medicines of the invention have the following properties, flavors, meridians and efficacies:
safflower: pungent flavor and warm nature. It enters heart and liver meridians. Has effects of promoting blood circulation, dredging channels, removing blood stasis, and relieving pain. Can be used for treating amenorrhea, dysmenorrhea, lochiorrhea, addiction, abdominal lump, thoracic obstruction, cardialgia, abdominal pain due to blood stasis, pricking pain in chest and hypochondrium, traumatic injury, and pyocutaneous disease with swelling and pain.
Three thirds: relieving spasm and pain, dispelling pathogenic wind and removing dampness. Warm in nature, bitter and pungent in flavor; it is toxic.
Short pedicel aconite root: bitter and numb, warm, and toxic; diminishing inflammation, relieving pain, dispelling wind and removing dampness; it can be used for treating traumatic injury, fracture, rheumatalgia, toothache, pyocutaneous disease, toxic swelling, and snake bite.
White dragon whiskers: bitter and astringent taste, slightly warm in nature. Invigorating spleen to promote digestion; moistening lung to arrest cough; mainly treats swollen sore throat; pulmonary tuberculosis; cough with hemoptysis; folding the belt; uterine prolapse.
The invention has the beneficial effects that: the medicinal liquor is mainly used for treating rheumatic joints, cervical and lumbar disc herniation and hyperosteogeny through years of practice, improvement, perfection and clinical proof, and has the characteristics of quick curative effect, short treatment course, treatment of both symptoms and root causes, high cure rate and no toxic or side effect; the preparation method of the invention is simple and the administration is convenient.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
In some more specific embodiments, the medicated wine comprises the following raw material medicines:
20-40 parts of safflower, 5-15 parts of kusnezoff monkshood root, 40-60 parts of pseudo-ginseng, 40-60 parts of acanthopanax, 40-60 parts of suberect spatholobus stem, 5-15 parts of nux vomica, 5-15 parts of short-pedicel aconite root, 15-25 parts of szechuan lovage rhizome, 15-25 parts of white dragon beard, 5-15 parts of acutangular anisodus root, 15-25 parts of tuber fleeceflower root, 15-25 parts of eucommia bark and 5-15 parts of common monkshood mother.
The preparation method comprises the following steps:
drying all the raw materials, soaking in 50% of Baguo wine for 5-9 days to obtain the medicated liquor for treating rheumatic arthritis and hyperosteogeny.
In some more specific embodiments, the medicated wine comprises the following bulk drugs:
25-35 parts of safflower, 8-12 parts of kusnezoff monkshood root, 45-55 parts of pseudo-ginseng, 45-55 parts of acanthopanax, 45-55 parts of suberect spatholobus stem, 8-12 parts of nux vomica, 6-14 parts of short-pedicel aconite root, 18-22 parts of szechuan lovage rhizome, 18-22 parts of white dragon beard, 8-12 parts of acutangular anisodus root, 19-21 parts of tuber fleeceflower root, 18-22 parts of eucommia bark and 8-22 parts of common monkshood mother.
The preparation method comprises the following steps:
drying all the raw materials, soaking in 50% (v/v) corn liquor for 7 days to obtain the medicated liquor for treating rheumatic arthritis and hyperosteogeny; sterilizing with flowing steam before drying, and drying at 80-90 deg.C until the water content of the dried raw materials is less than or equal to 5 wt%.
In the following examples, 1 part of 1 part represents 1 g.
Example 1
The embodiment provides a medicinal liquor for treating rheumatic joints and hyperosteogeny, which comprises the following raw material medicines:
20 parts of safflower, 15 parts of kusnezoff monkshood root, 40 parts of pseudo-ginseng, 60 parts of acanthopanax, 40 parts of suberect spatholobus stem, 15 parts of nux vomica, 5 parts of short-pedicel aconite root, 25 parts of szechuan lovage rhizome, 15 parts of white dragon beard, 15 parts of acutangular anisodus root, 15 parts of tuber fleeceflower root, 15 parts of eucommia bark and 15 parts of common monkshood.
The method for preparing the medicinal liquor for treating the rheumatic joint and the hyperosteogeny comprises the following steps:
drying all the raw materials, soaking in 50% of Baguo wine for 5 days to obtain the medicated liquor for treating rheumatic arthritis and hyperosteogeny.
Example 2
The embodiment provides a medicinal liquor for treating rheumatic joints and hyperosteogeny, which comprises the following raw material medicines:
30 parts of safflower, 10 parts of kusnezoff monkshood root, 50 parts of pseudo-ginseng, 50 parts of acanthopanax, 50 parts of suberect spatholobus stem, 10 parts of nux vomica, 10 parts of short-pedicel aconite root, 20 parts of szechuan lovage rhizome, 20 parts of white dragon beard, 10 parts of acutangular anisodus root, 20 parts of tuber fleeceflower root, 20 parts of eucommia bark and 10 parts of common monkshood.
The method for preparing the medicinal liquor for treating the rheumatic joint and the hyperosteogeny comprises the following steps:
drying all the raw materials, soaking in 50% (v/v) corn liquor for 7 days to obtain the medicated liquor for treating rheumatic arthritis and hyperosteogeny; sterilizing with flowing steam before drying, and drying at 80-90 deg.C until the water content of the dried raw materials is less than or equal to 5 wt%.
And (3) counting clinical data:
the inventor carries out clinical treatment statistics on 100 cases of lumbar vertebra hyperosteogeny patients, 100 cases of cervical vertebra hyperosteogeny patients and 100 cases of patients suffering from both lumbar vertebra hyperosteogeny and cervical vertebra hyperosteogeny, and each patient drinks the medicinal liquor three times a day, 1 two times each time and continuously drinks for 30 days. 36 patients with lumbar vertebra hyperosteogeny, 42 patients with cervical vertebra hyperosteogeny and 21 patients with lumbar vertebra hyperosteogeny and cervical vertebra hyperosteogeny are cured clinically; effective cases: 62 patients with lumbar vertebra hyperosteogeny, 54 patients with cervical vertebra hyperosteogeny, and 67 patients with the lumbar vertebra hyperosteogeny and the cervical vertebra hyperosteogeny at the same time, wherein the total effective rate of the patients with the lumbar vertebra hyperosteogeny is 98 percent, and the cure rate is 36 percent; the total effective rate of the cervical vertebra hyperosteogeny patients is 96 percent, and the cure rate is 42 percent; the total effective rate of the patient suffering from lumbar vertebra hyperosteogeny and cervical vertebra hyperosteogeny is 88 percent, and the cure rate is 21 percent.
The present invention is not limited to the above-mentioned preferred embodiments, and any other products in various forms can be obtained by anyone in the light of the present invention, but any changes in the shape or structure thereof, which have the same or similar technical solutions as those of the present application, fall within the protection scope of the present invention.

Claims (9)

1. The medicinal liquor for treating rheumatic joint and hyperosteogeny is characterized by comprising the following raw material medicines:
safflower, kusnezoff monkshood root, pseudo-ginseng, acanthopanax, suberect spatholobus stem, nux vomica, short-pedicel aconite root, szechuan lovage rhizome, white dragon beard, acutangular anisodus root, tuber fleeceflower root, eucommia bark and common monkshood mother root.
2. The medicinal liquor for treating rheumatic joints and hyperosteogeny according to claim 1, which comprises the following raw material medicines in parts by weight:
20-40 parts of safflower, 5-15 parts of kusnezoff monkshood root, 40-60 parts of pseudo-ginseng, 40-60 parts of acanthopanax, 40-60 parts of suberect spatholobus stem, 5-15 parts of nux vomica, 5-15 parts of short-pedicel aconite root, 15-25 parts of szechuan lovage rhizome, 15-25 parts of white dragon beard, 5-15 parts of acutangular anisodus root, 15-25 parts of tuber fleeceflower root, 15-25 parts of eucommia bark and 5-15 parts of common monkshood mother.
3. The medicinal liquor for treating rheumatic joints and hyperosteogeny according to claim 2, which comprises the following raw material medicines in parts by weight:
25-35 parts of safflower, 8-12 parts of kusnezoff monkshood root, 45-55 parts of pseudo-ginseng, 45-55 parts of acanthopanax, 45-55 parts of suberect spatholobus stem, 8-12 parts of nux vomica, 6-14 parts of short-pedicel aconite root, 18-22 parts of szechuan lovage rhizome, 18-22 parts of white dragon beard, 8-12 parts of acutangular anisodus root, 19-21 parts of tuber fleeceflower root, 18-22 parts of eucommia bark and 8-22 parts of common monkshood mother.
4. The medicinal liquor for treating rheumatic joints and hyperosteogeny according to claim 3, which comprises the following raw material medicines in parts by weight:
30 parts of safflower, 10 parts of kusnezoff monkshood root, 50 parts of pseudo-ginseng, 50 parts of acanthopanax, 50 parts of suberect spatholobus stem, 10 parts of nux vomica, 10 parts of short-pedicel aconite root, 20 parts of szechuan lovage rhizome, 20 parts of white dragon beard, 10 parts of acutangular anisodus root, 20 parts of tuber fleeceflower root, 20 parts of eucommia bark and 10 parts of common monkshood.
5. A method for preparing the medicinal liquor for treating the rheumatic joint and the hyperosteogeny according to any one of the claims 1 to 4, which is characterized by comprising the following steps:
drying all the raw materials, soaking in wine for 5-9 days to obtain the medicated liquor for treating rheumatic arthritis and hyperosteogeny.
6. The method for preparing medicated wine for treating rheumatic joint and hyperosteogeny according to claim 5, wherein said wine is corn wine, and the alcohol content of said wine is 50 °.
7. The method for preparing the medicinal liquor for treating the rheumatic joint and the hyperosteogeny according to claim 5, wherein all the raw material medicines are sterilized by flowing steam before being dried and then dried at the high temperature of 80-90 ℃ until the water content of the raw material medicines is less than or equal to 5wt percent after being dried.
8. The method for preparing medicated wine for treating rheumatic joint and hyperosteogeny according to claim 5, wherein said soaking time is 7 days.
9. A medicine comprising the medicinal liquor for treating rheumatic joints and hyperosteogeny according to claims 1 to 4.
CN202010252124.4A 2020-04-01 2020-04-01 Medicinal liquor for treating rheumatic joint and hyperosteogeny and preparation method thereof Pending CN111228363A (en)

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CN104771654A (en) * 2015-04-24 2015-07-15 杨帮德 Traditional Chinese medicine for treating lumbar vertebra hyperostosis and cervical vertebra hyperostosis and preparation method thereof
CN106138422A (en) * 2015-04-15 2016-11-23 王言 A kind of medicated wine and preparation method thereof

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CN106138422A (en) * 2015-04-15 2016-11-23 王言 A kind of medicated wine and preparation method thereof
CN104771654A (en) * 2015-04-24 2015-07-15 杨帮德 Traditional Chinese medicine for treating lumbar vertebra hyperostosis and cervical vertebra hyperostosis and preparation method thereof

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