CN111226914A - Emamectin benzoate and chlorantraniliprole compound insecticidal composition - Google Patents
Emamectin benzoate and chlorantraniliprole compound insecticidal composition Download PDFInfo
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- CN111226914A CN111226914A CN202010139861.3A CN202010139861A CN111226914A CN 111226914 A CN111226914 A CN 111226914A CN 202010139861 A CN202010139861 A CN 202010139861A CN 111226914 A CN111226914 A CN 111226914A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
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Abstract
The invention relates to the technical field of pesticides, and particularly relates to an insecticidal composition containing emamectin benzoate and chlorantraniliprole. The weight ratio of the emamectin benzoate to the chlorantraniliprole in the composition is 2: 1-1: 4; the preparation raw materials of the compound insecticidal composition also comprise alkoxylated tallow alcohol. The emamectin benzoate and chlorantraniliprole compound insecticidal composition has good compatibility effect and has high inhibition and killing effects on rice stem borers and other insects. Meanwhile, the composition has high dispersion stability, high-temperature stability, low-temperature stability and good prevention and treatment effect, and is suitable for being used in various environments.
Description
Technical Field
The invention relates to the technical field of pesticides, and particularly relates to an insecticidal composition containing emamectin benzoate and chlorantraniliprole.
Background
Chilosurla chilo (Walker) belongs to Lepidoptera and Bombycidae, is one of the most serious common pests on rice in China, eats the stem of the rice, damages the rice in the tillering stage, and causes withered sheaths and dead heart seedlings; causing withered booting ears and white ears for rice in booting ears and heading stage; damaging rice in the milk stage to cause semi-withered ears and insect-damaged plants.
The chemical name of chlorantraniliprole is 3-bromo-N- { 4-chloro-2-methyl-6- [ (methylamino) carbonyl ] phenyl } -1- (3-chloro-2-pyridyl) -1H-pyrazole-5-amide. Chlorantraniliprole is a brand-new high-efficiency low-toxicity insecticide, and the insecticidal mechanism is different from that of the traditional insecticide. Chlorantraniliprole can efficiently activate ryanodine (muscle) receptors of insects, so that calcium ions in intracellular calcium reservoirs are excessively released, and the insects die paralytically. The chlorantraniliprole has the effects of contact killing and stomach toxicity, shows the characteristics of high efficiency, broad spectrum, lasting effect, novel action mechanism and the like, can be used for preventing and controlling various lepidoptera pests, has the prevention and control effect obviously superior to that of other commercial pesticide varieties used in the current production, has no interactive resistance to other pesticides, is safe to natural enemy insects, can be used for comprehensive treatment and resistance treatment of the pests, and is used for preventing and controlling various pests of crops such as vegetables, beet, cotton and the like, such as asparagus caterpillar, cabbage looper, diamond back moth, cabbage butterfly, cotton bollworm, pink bollworm and the like, and has good prevention and control effect on larvae in various ages.
The emamectin benzoate is agricultural antibiotic abamectin B1The structural modification product has stomach toxicity as main action mode and certain contact poisoning effect. The action mechanism is to enhance the action of neurotransmitter such as glutamate and gamma-aminobutyric acid, so that a large amount of chloride ions are introduced into nerve cells, and the cells are enabled to haveLoss of function, disturbance of nerve conduction, termination of feeding by the larvae soon after exposure to the agent, and irreversible paralysis. The agent can penetrate into the epidermis of target crops to form an effective storage layer, and has long-term drug effect. Meanwhile, the dosage is small, and the degradation is easy, so that the environment is not polluted and has no residue. Research tests show that the emamectin benzoate has good effect at very low dosage, does not harm beneficial insects in the process of controlling pests, and is highly safe to crops. The emamectin benzoate is an efficient, high-selectivity, green, environment-friendly and biological insecticide.
However, emamectin benzoate has good quick-acting property, is easy to photolyze and has poor persistence. And the long-term use of chlorantraniliprole can easily cause the resistance of pests to the drugs and influence the control effect of the drugs. In addition, the applicant finds that the effects of the pharmaceutical composition obtained by compounding in a laboratory in the field test process are not consistent, which is probably related to factors such as specific dosage form of the medicine, stability in the application process and after application, sensitivity to the application environment and the like, and the applicant develops the emamectin benzoate and chlorantraniliprole compound insecticidal composition with high stability and high-efficiency control effect on rice stem borer by combining the factors.
Disclosure of Invention
In order to solve the technical problems, the invention provides a emamectin benzoate and chlorantraniliprole compound insecticidal composition in a first aspect, wherein the weight ratio of the emamectin benzoate to the chlorantraniliprole is 2: 1-1: 4; the preparation raw materials of the compound insecticidal composition also comprise alkoxylated tallow alcohol.
In a preferred embodiment, the amount of the alkoxylated tallow alcohol is at least 60 wt% based on the weight of the emamectin benzoate.
As a preferable technical scheme, the formulation of the compound insecticidal composition comprises dispersible oil suspending agent, seed coating agent, wettable powder and water dispersible granule.
As a preferable technical scheme, the preparation raw materials of the dispersible oil suspending agent also comprise 1-10 wt% of wetting dispersant, 0.5-5 wt% of thickening agent, 1-6 wt% of antifreezing agent and the balance of dispersing medium;
the preparation method of the dispersible oil suspending agent comprises the following steps:
according to the raw material component ratio, chlorantraniliprole, emamectin benzoate, alkoxylated tallow alcohol and wetting dispersant are subjected to high-speed shearing, mixed and dispersed, the medicine is ground under the action of mechanical energy, the medicine is sheared and broken into particles with the diameter less than 5 micrometers, then thickening agent, antifreezing agent and dispersing medium are added into a high-shear dispersing agent machine, and the dispersible oil suspending agent is obtained through shearing and mixing.
As a preferable technical scheme, the preparation raw material of the compound insecticidal composition comprises isosorbide derivatives.
As a preferred technical scheme, the isosorbide derivative is compound a and or compound B, compound a has the following structural formula:
wherein R is1Is an alkyl chain of C6-C16.
As a preferred technical scheme, the R is1Is a C8-C12 aliphatic alkyl chain.
As a preferred embodiment, the compound B has the following structural formula:
wherein R is1Is an alkyl chain containing hydroxyl.
As a preferable technical scheme, the alkyl chain containing the hydroxyl is-CH2CH(OH)OC(＝O)CH(＝CH2)CH3。
The invention also provides the application of the emamectin benzoate and chlorantraniliprole compound insecticidal composition in the aspect of rice insect damage.
The emamectin benzoate and chlorantraniliprole compound insecticidal composition has good compatibility effect and has high inhibition and killing effects on rice stem borers and other insects. Meanwhile, the high-performance nano-composite material has high dispersion stability, high-temperature stability, low-temperature stability and physical and chemical stability, and is suitable for being used in various environments.
Detailed Description
The technical features of the technical solutions provided by the present invention are further clearly and completely described below with reference to the specific embodiments, and the scope of protection is not limited thereto.
The words "preferred", "preferably", "more preferred", and the like, in the present invention, refer to embodiments of the invention that may provide certain benefits, under certain circumstances. However, other embodiments may be preferred, under the same or other circumstances. Furthermore, the recitation of one or more preferred embodiments does not imply that other embodiments are not useful, nor is it intended to exclude other embodiments from the scope of the invention.
It will be understood by those skilled in the art that, unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the prior art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
In order to solve the technical problems, the invention provides a emamectin benzoate and chlorantraniliprole compound insecticidal composition in a first aspect, wherein the weight ratio of the emamectin benzoate to the chlorantraniliprole is 2: 1-1: 4; the preparation raw materials of the compound insecticidal composition also comprise alkoxylated tallow alcohol.
The emamectin benzoate is agricultural antibiotic abamectin B1The structural modification product has stomach toxicity as main action mode and certain contact poisoning effect. Therefore, the emamectin benzoate for killing the rice stem borers and other insects needs to penetrate into the tissues of the insects to a great extent and has a certain paralysis effect to take effect.
The chemical name of chlorantraniliprole in the invention is 3-bromo-N- { 4-chloro-2-methyl-6- [ (methylamino) carbonyl ] phenyl } -1- (3-chloro-2-pyridyl) -1H-pyrazole-5-amide. Due to the unique chemical structure, chlorantraniliprole can permeate into the body of pests to activate ryanodine receptors in the muscles of the pests, so that calcium ions in the pests are released without limit, the muscles are prevented from contracting, and the pests are killed. Therefore, the chlorantraniliprole can contact pests to a certain extent to kill the pests and can only permeate into the bodies of the pests to play a better role.
The source of the alkoxylated tallow alcohol in the present invention is not particularly limited, and can be prepared by the alkoxylation method of alcohols well known to those skilled in the art, or can be purchased from the market, or can be purchased from the winning Chuangdegusai.
In some embodiments, the alkoxylated tallow alcohol is present in an amount of at least 60 wt% based on the weight of the emamectin benzoate.
Preferably, the amount of alkoxylated tallow alcohol is not more than twice the weight of the emamectin benzoate.
Further preferably, the weight ratio of the emamectin benzoate to the alkoxylated tallow alcohol is 5: (3-8).
The applicant finds that the stability of the dispersible oil suspending agent prepared from the compound insecticidal composition can be improved to a great extent by adding a certain amount of alkoxylated tallow alcohol into the compound insecticidal composition, and the killing effect of the compound insecticidal composition on rice stem borers and other insects can also be remarkably improved. Probably because the alkoxylated tallow alcohol structure contains a long aliphatic alkyl chain and an alkoxy chain segment, the long alkyl chain is helpful for improving the acting force between the tallow alcohol and hydrophobic pyridine, benzene ring and other structures in the chlorantraniliprole structure, and simultaneously improving the van der waals force between the nonpolar chain segment in the chlorantraniliprole structure and the nonpolar chain segment in the emamectin benzoate structure, and improving the mutual dispersion and the synergistic interaction between the two drugs. Meanwhile, the cohesive energy density of the tallow alcohol is further reduced after the alkoxylation modification, when the composition is prepared into the dispersible oil suspending agent, the surface tension of a system can be reduced, the active pharmaceutical ingredients in the system can be dispersed in a smaller particle form, unstable phenomena such as flocculation aggregation and the like caused by factors such as temperature, centrifugal force and the like among particles are avoided, the suspension rate of the dispersible oil suspending agent is effectively improved, and the active pharmaceutical ingredients in the system can better exert the effect of killing pests.
The emamectin benzoate and chlorantraniliprole compound insecticidal composition can be used for killing rice stem borers, the dosage form of the insecticide is not specially limited, and various dosage forms well known to a person skilled in the art can be selected, such as seed coating agent, wettable powder, microemulsion, emulsion, water dispersible granule, dispersible oil suspending agent and the like.
In some embodiments, the formulation of the compound insecticidal composition comprises dispersible oil suspending agent, seed coating agent, wettable powder and water dispersible granule.
Preferably, the dispersible oil suspending agent also comprises 1-10 wt% of wetting dispersant, 0.5-5 wt% of thickener, 1-6 wt% of antifreeze and the balance of dispersing medium.
The preparation method of the dispersible oil suspending agent comprises the following steps:
adding chlorantraniliprole, emamectin benzoate, alkoxylated tallow alcohol, a wetting dispersant, a thickening agent, an antifreezing agent and the balance of dispersion medium into a high-shear dispersant machine according to the raw material component ratio, and then sanding and screening to obtain the dispersible oil suspending agent with the particle size of 0.1-5 microns.
In the invention, the type of the wetting dispersant is not particularly limited, and sodium alkyl benzene sulfonate, sodium lignosulfonate, fatty alcohol, alkyl sulfate, alkylphenol polyoxyethylene, sodium naphthalenesulfonate formaldehyde condensate, lauryl alcohol polyoxyethylene ether, phenethylphenol polyoxyethylene ether, tristyrylphenol polyoxyethylene ether phosphate, castor oil ethylene oxide adduct, diphenylphenol polyoxyethylene polyoxypropylene ether, diphenylphenol polyoxyethylene ether formaldehyde condensate and the like can be selected.
The thickening agent is not specially limited, and fumed silica, bentonite, aluminum silicate, methyl cellulose, glucose, xanthan gum, magnesium aluminum silicate, polyvinyl alcohol and the like can be selected.
The antifreeze is not particularly limited in the present invention, and glycerin, propylene glycol, ethylene glycol, urea, glucose, polyethylene glycol, sodium chloride, sodium sulfate, and the like can be selected.
In the invention, the dosage form of the compound composition and the dosage of auxiliary materials and auxiliary components such as a dispersing agent, an antifreezing agent and the like selected in a specific dosage form are approximate components, and besides the specific auxiliary components listed above, other components known by persons skilled in the art can be added on the premise of not influencing the specific dosage form to further improve the corresponding performance of the dosage form.
In some embodiments, the raw materials for preparing the compounded insecticidal composition include an isosorbide derivative.
Preferably, the weight ratio of the isosorbide derivative to the alkoxylated tallow alcohol is (2: 3) to (3: 2).
Further preferably, the weight ratio of the isosorbide derivative to emamectin benzoate is 1: 1.
the isosorbide derivative is a component obtained by taking isosorbide as a basic raw material and carrying out various chemical reactions, and comprises chemical components such as isosorbide ether, isosorbide ester, isosorbide polymer, hydroxyisosorbide derivative and the like. Isosorbide is composed of two symmetrical five-membered exchange structures sharing two carbons, has high rigidity, can keep the original state under the action of higher temperature, shearing force and the like, has low sensitivity to the conditions, and has weak acting force with the active pharmaceutical ingredients such as emamectin benzoate, chlorantraniliprole and the like.
In some embodiments, the isosorbide derivative is compound a and or compound B, wherein compound a has the following structural formula:
wherein R is1Is an alkyl chain of C6-C16.
Compound a in the present invention is a single-side reacted isosorbide ether compound, which can be prepared by methods well known to those skilled in the art, or can be purchased from the market, and its preparation can be carried out as follows:
3 moles of isosorbide are dissolved in DMSO and the mixture is heated to 120 ℃. Subsequently, 1 mole of NaOH was added to the mixture, and then 1 mole of C6-C16 alkyl chloride was added dropwise to the reaction mixture. After completion of the reaction, the upper phase was washed 3 times with brine and once with warm water. Distilling the crude product to obtain a light yellow solid, namely the compound A.
In some preferred embodiments, R is1Is a C8-C12 aliphatic alkyl chain.
Preferably, said R is1Is a C12 aliphatic alkyl chain (preferably lauryl/dodecyl).
In some embodiments, the compound B has the following structural formula:
wherein R is1Is an alkyl chain containing hydroxyl.
The compound B in the invention is a product obtained by ring-opening reaction of isosorbide and a compound containing an ethylene oxide structure under the action of a phase transfer catalyst, and can be obtained by the independent reaction of isosorbide and a substance containing the ethylene oxide structure, or obtained by the reaction of isosorbide, ethylene oxide and unsaturated olefin, wherein the specific reaction is carried out according to a method well known by a person skilled in the art.
Preferably, the alkyl chain containing hydroxyl is-CH2CH(OH)OC(＝O)CH(＝CH2)CH3。
The preferred compound B is a product obtained by reacting isosorbide with glycidyl methacrylate in the presence of a catalyst through an epoxy ring-opening reaction to react with hydroxyl groups on isosorbide, and the preparation process can be operated according to the following reaction formula:
1 mole of isosorbide is reacted with 4 moles of ethylene oxide and catalytic amounts of KOH (0.025 mole) at a temperature of 160 ℃, the epoxide content is determined by titration during the reaction, the reaction is terminated when the epoxide content has dropped to 1/20 of the starting value, the product is cooled and neutralized by adding a sufficient amount of lactic acid, and then after work-up compound B is obtained, the reaction yield being up to 90% or more.
In a preferred embodiment, the isosorbide derivative consists of compound A and compound B.
Preferably, the weight ratio of compound a to compound B is 2: 3.
the applicant finds that the addition of a certain amount of isosorbide compound into the emamectin benzoate and chlorantraniliprole compound insecticidal composition can further improve the killing effect of the composition on rice stem borers and other insects, and the effect of the composition cannot be obviously influenced even if the composition is sprayed in special environments such as high-strength rainfall, wind blowing and the like. Furthermore, the applicant has unexpectedly found that the addition of an amount of isosorbide compound, especially when the weight ratio of compound a to compound B is 2: and 3, the storage stability of the emamectin benzoate and chlorantraniliprole compound insecticidal composition is remarkably improved, and the dispersion stability and other parameters of the emamectin benzoate and chlorantraniliprole compound insecticidal composition can be remarkably improved. Probably, after the compound insecticidal composition is prepared into the dispersible oil suspending agent, the active medicament in the oil suspending agent is coated in the micelle formed by the oil suspending agent by components such as alkoxylated tallow alcohol, isosorbide derivatives and the like, so that the active medicament is uniformly dispersed. The alkoxylated tallow alcohol has a longer molecular chain structure, so that thicker-walled micelles can be formed, but the micelles are looser due to the distribution of hydrophilic and hydrophobic groups of the long molecular chains, when the temperature of a system is increased, the molecules are easily in an unstable state due to Brownian motion, the micelles are easily broken, active drugs in the micelles are forced to be released out of the micelles, flocculation and agglomeration are caused, the suspension rate is reduced, and the contact capacity and the contact area of the drugs on rice stem borers and the like and the permeation inside the worms are influenced due to the agglomeration of the drugs, so that the exertion of the drug efficacy is influenced.
When the alkoxylated tallow alcohol exists in the system, a specific amount of isosorbide derivatives is added, and the isosorbide derivatives are randomly inserted into micelles formed by the alkoxylated tallow alcohol due to the special amphiphilic effect, so that the micelles become more compact, and the stability of the micelles is strengthened. Meanwhile, due to the high content of the cyclic structure in the isosorbide, the rigidity is high, and the sensitivity to temperature, shearing force and the like is mutually balanced, so that the isosorbide is not easy to have severe response when being stimulated by high temperature, centrifugation and the like, and can better keep the original micelle state, thereby improving the stability of the dispersible oil suspending agent. In addition, the alkoxylated tallow alcohol, the isosorbide derivatives and the like improve the stability of the suspending agent, and the like, and the medicament is easy to permeate into crops after being sprayed, so that a film is formed on the surfaces of the crops, and even if strong external acting force such as rainwater scouring is applied, the film is not easy to scour and cannot achieve the effect.
The invention also provides the application of the emamectin benzoate and chlorantraniliprole compound insecticidal composition in the aspect of rice insect damage.
The pests are not specially limited in the invention, such as rice moths, rice stem borers, leaf rollers, rice caraway rice planthopper thrips and the like.
The present invention will be specifically described below by way of examples. It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention. In addition, all the raw materials used were ordinary commercial products unless otherwise specified.
Examples
Embodiment 1 provides a dispersible oil suspending agent, which is prepared from emamectin benzoate and chlorantraniliprole compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
the dispersible oil suspending agent is prepared by the steps of subjecting 20 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 3 wt% of alkoxylated tallow alcohol, 7 wt% of wetting dispersant and 12 wt% of corn oil to high-speed shearing, mixing and dispersing, grinding the medicine under the action of mechanical energy to enable the medicine to be sheared and broken into particles with the diameter smaller than 5 microns, adding 3 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shearing disperser, and shearing and mixing.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Embodiment 2 provides a dispersible oil suspending agent, which is prepared from emamectin benzoate and chlorantraniliprole compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
the dispersible oil suspending agent is prepared by the steps of carrying out high-speed shearing on 15 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 6 wt% of alkoxylated tallow alcohol, 5 wt% of wetting dispersant and 12 wt% of corn oil, mixing and dispersing, grinding the medicine under the action of mechanical energy to enable the medicine to be sheared and broken into particles with the diameter smaller than 5 microns, then adding 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shearing disperser, and carrying out shearing and mixing.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Embodiment 3 provides a dispersible oil suspending agent, which is prepared from emamectin benzoate and chlorantraniliprole compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
10 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 8 wt% of alkoxylated tallow alcohol, 2 wt% of wetting dispersant and 12 wt% of corn oil are subjected to high-speed shearing, mixed and dispersed, the medicine is ground under the action of mechanical energy, the medicine is sheared and broken into particles with the diameter less than 5 microns, then 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil are added into a high-shearing disperser, and the dispersible oil suspending agent is obtained through shearing and mixing.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Embodiment 4 provides a dispersible oil suspending agent, which is prepared from emamectin benzoate and chlorantraniliprole compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
the dispersible oil suspending agent is prepared by the steps of subjecting 5 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 8 wt% of alkoxylated tallow alcohol, 2 wt% of wetting dispersant and 12 wt% of corn oil to high-speed shearing, mixing and dispersing, grinding the medicine under the action of mechanical energy to enable the medicine to be sheared and broken into particles with the diameter smaller than 5 microns, adding 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shearing disperser, and shearing and mixing.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Embodiment 5 provides a dispersible oil suspending agent, which is prepared from emamectin benzoate and chlorantraniliprole compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
the dispersible oil suspending agent is prepared by the steps of subjecting 5 wt% of chlorantraniliprole, 10 wt% of emamectin benzoate, 8 wt% of alkoxylated tallow alcohol, 2 wt% of wetting dispersant and 12 wt% of corn oil to high-speed shearing, mixing and dispersing, grinding the medicine under the action of mechanical energy to enable the medicine to be sheared and broken into particles with the diameter smaller than 5 microns, adding 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shearing disperser, and shearing and mixing.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Embodiment 6 provides a dispersible oil suspending agent, which is prepared from emamectin benzoate and chlorantraniliprole compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
carrying out high-speed shearing on 15 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 6 wt% of alkoxylated tallow alcohol, 4 wt% of isosorbide derivative (compound A), 5 wt% of wetting dispersant and 12 wt% of corn oil, mixing and dispersing, grinding the medicament under the action of mechanical energy to ensure that the medicament is sheared and broken into particles with the diameter less than 5 microns, then adding 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shear dispersing machine, and shearing and mixing to obtain the dispersible oil suspending agent.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Embodiment 7 provides a dispersible oil suspending agent, which is prepared from emamectin benzoate and chlorantraniliprole compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
carrying out high-speed shearing on 15 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 6 wt% of alkoxylated tallow alcohol, 8 wt% of isosorbide derivative (compound B), 5 wt% of wetting dispersant and 12 wt% of corn oil, mixing and dispersing, grinding the medicament under the action of mechanical energy to ensure that the medicament is sheared and broken into particles with the diameter less than 5 microns, then adding 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shear dispersing machine, and shearing and mixing to obtain the dispersible oil suspending agent.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Embodiment 8 provides a dispersible oil suspending agent, which is prepared from emamectin benzoate and chlorantraniliprole compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
carrying out high-speed shearing, mixing and dispersing on 15 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 6 wt% of alkoxylated tallow alcohol, 5 wt% of isosorbide derivatives (composed of a compound A and a compound B and having a weight ratio of 2: 3), 5 wt% of wetting dispersant and 12 wt% of corn oil, grinding the medicaments under the action of mechanical energy to ensure that the medicaments are sheared and broken into particles with the diameter of less than 5 micrometers, then adding 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shearing machine, and shearing and mixing to obtain the dispersible oil suspending agent.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Example 9 provides a dispersible oil suspension concentrate prepared from emamectin benzoate and chlorantraniliprole compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
carrying out high-speed shearing on 15 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 5 wt% of isosorbide derivatives (composed of a compound A and a compound B in a weight ratio of 2: 3), 5 wt% of wetting dispersant and 12 wt% of corn oil, mixing and dispersing, grinding the medicines under the action of mechanical energy to ensure that the medicines are sheared and broken into particles with the diameter less than 5 microns, then adding 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shear disperser, and shearing and mixing to obtain the dispersible oil suspending agent.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Example 10 provides a dispersible oil suspension concentrate prepared from emamectin benzoate and chlorantraniliprole compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
carrying out high-speed shearing on 15 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 5 wt% of isosorbide derivatives (consisting of the compound A), 5 wt% of wetting dispersant and 12 wt% of corn oil, mixing and dispersing, grinding the medicaments under the action of mechanical energy to ensure that the medicaments are sheared and broken into particles with the diameter less than 5 microns, then adding 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shear disperser, and carrying out shearing and mixing to obtain the dispersible oil suspending agent.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Example 11 provides a dispersible oil suspension formulation prepared from emamectin benzoate and chlorantraniliprole as a compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
carrying out high-speed shearing on 15 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 5 wt% of isosorbide derivatives (consisting of compounds B), 5 wt% of wetting dispersant and 12 wt% of corn oil, mixing and dispersing, grinding the medicaments under the action of mechanical energy to ensure that the medicaments are sheared and broken into particles with the diameter less than 5 microns, then adding 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shear disperser, and carrying out shearing and mixing to obtain the dispersible oil suspending agent.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Example 12 provides a dispersible oil suspension concentrate prepared from emamectin benzoate and chlorantraniliprole as a compounded insecticidal composition.
The preparation method of the dispersible oil suspending agent comprises the following steps:
carrying out high-speed shearing on 15 wt% of chlorantraniliprole, 5 wt% of emamectin benzoate, 6 wt% of alkoxylated tallow alcohol, 5 wt% of isosorbide, 5 wt% of wetting dispersant and 12 wt% of corn oil, mixing and dispersing, grinding the medicament under the action of mechanical energy to ensure that the medicament is sheared and broken into particles with the diameter less than 5 microns, then adding 4 wt% of thickening agent, 2 wt% of antifreezing agent and the balance of corn oil into a high-shear disperser, and shearing and mixing to obtain the dispersible oil suspending agent.
The wetting dispersant is a mixture of phenylethylphenol polyoxyethylene ether and triphenylethylphenol polyoxyethylene ether phosphate with equal weight; the thickening agent is xanthan gum; the antifreezing agent is glycerol.
Evaluation of Performance
In order to determine the compatibility effect between the emamectin benzoate and chlorantraniliprole, the toxicity test of the mixture on the rice stem borer is awakened. The experimental conditions are that the temperature is 25 +/-1 ℃, the relative humidity is 60-80%, and the illumination period is L: d ═ 16: 8) h. 77% of emamectin benzoate; 97% of chlorantraniliprole is provided by Shanghai Yueji Biotech limited.
The test method comprises the following steps: reference is made to bioassay Standard NY/T1154.14-2008. Cutting fresh and tender rice grain, soaking in the test solution for 10s, taking out, placing into a prepared glass test tube, placing 5 sections of rice grain into each tube, naturally drying, then placing 10 rice-stem borers of 3 rd age into the test tube, fastening the tube opening with gauze, repeating for 4 times per chalinary, and placing in an observation room for culturing after the treatment is finished.
The investigation method comprises the following steps: and peeling rice after 72 hours of treatment, checking the death condition of the test, recording, and recording the death condition of the test insects, wherein the death judgment standard is that no response is recorded as death when the test insects are lightly contacted with tweezers.
The method for evaluating the synergistic effect comprises the following steps: the synergy of the mixed medicament is evaluated by adopting a co-toxicity coefficient method (CTC) according to Sun & Johnson (1960) by referring to a biological test standard method NY/T1154.7-2006, namely that the CTC is not more than 80 as an antagonistic action, the CTC is more than 80 and less than 120 as an additive action, and the CTC is not less than 120 as a synergistic action.
Measured virulence index (ATI) ═ standard agent EC50Reagent for test EC50)*100
Theoretical virulence index (TTI) of the mixture agent a percent (%) of agent a + B percent (%) of agent B in the mixture
Co-toxicity coefficient (CTC) ═ mix observed virulence index (ATI)/mix theoretical virulence index (TTI) ] + 100.
The statistical analysis method comprises the following steps: all experimental data were analyzed using dpssv 7.05 statistical software. Calculating mortality (%) according to experimental data, and determining virulence regression line, correlation coefficient, LC50And LC90And 95% confidence limits, the test results are shown in table 1.
TABLE 1 toxicity test results of pesticide composition containing emamectin benzoate and chlorantraniliprole for rice stem borer
As can be seen from the above table, emamectin benzoate and chlorantraniliprole are present in a ratio of 2: 1,1: 1,1: 2,1: 3,1: 4, the mixture has a synergistic effect on rice stem borers, wherein the ratio of emamectin benzoate to chlorantraniliprole is 1: 2, the compounding synergistic effect is most obvious, but the optimal compounding proportion needs to be determined by considering a plurality of factors such as field test effect, stability and the like.
In addition, the stability and field efficacy test of examples 1 to 12 was carried out, specifically:
1. the test method of high temperature stability comprises the following steps: after the dispersible oil suspending agent prepared in the embodiment is stored for 14 days at 54 ℃, the stability of the dispersible oil suspending agent is evaluated at 0-4 level, the 0 level stability is the best, and the 4 level stability is the worst by observing whether the appearance of the dispersible oil suspending agent is in a loose granular shape or not and whether the dispersible oil suspending agent is bonded or not and whether the appearance of the dispersible oil suspending agent is free of layering water absorption.
2. And (3) testing dispersion stability: and (3) testing dispersion stability: the test was carried out according to the method described in HG/T2467.11-2003, essentially preparing a dispersion at a given concentration, placing it in two graduated emulsion tubes respectively, standing for a certain period of time, pouring the tubes several times, and observing the dispersion initially, after standing for a certain period of time and after redispersion. Wherein
The superior grade: initial dispersibility-complete dispersion; dispersibility-precipitation <5.0ml, cream or oil slick <3.0ml for 30 min; redispersion-24 h precipitation <1.0ml, cream or oil slick <2.0 ml.
Good grade: initial dispersibility-complete dispersion; dispersibility-precipitation <8.0ml, cream or oil slick <5.0ml for 30 min; redispersion-24 h precipitation <1.5ml, cream or oil slick <3.0 ml.
Unqualified: initial dispersability-incomplete dispersion; 30min dispersibility-precipitation >8.0ml, cream or oil slick >5.0 ml; redispersion-24 h >1.5ml pellet, cream or creme >3.0 ml.
3. Freeze-thaw stability: freezing the dispersible oil suspending agent, observing whether layering and precipitation phenomena exist after the dispersible oil suspending agent is dissolved, and determining that the dispersible oil suspending agent is qualified, otherwise, determining that the dispersible oil suspending agent is not qualified.
4. And (3) field small experiment: the pesticide is applied at the peak period of the rice stem borer, and is uniformly sprayed according to the water adding amount of 50kg per mu, and the water adding amount is 25m per district2Repeating the steps for 4 times, investigating the control effect 7 days and 15 days after the medicine application, and carrying out obvious difference analysis, wherein the investigation method adopts a 5-point sampling method and examines 25 acupoints in total.
TABLE 2 Emamectin benzoate and Chlorantraniliprole Compound insecticidal composition stability and field test
As is obvious from the table, the insecticidal composition compounded by the specific alkoxylated tallow alcohol, the specific proportion of isosorbide derivatives, and the specific proportion of emamectin benzoate and chlorantraniliprole has good effect of killing rice stem borers, wherein the dispersible oil suspending agent which is derived from the specific weight parts and the specific isosorbide, contains 5 wt% of emamectin benzoate and 15% of chlorantraniliprole has the most obvious effect of preventing and treating the rice stem borers.
In addition, the applicant entrusts Chongqing Lvang agricultural science and technology limited company to perform a field pesticide effect test on the dispersible oil suspending agent in the invention for preventing and controlling cabbage prodenia litura and rice stem borer, which comprises the following specific steps:
prevention and control of rice stem borer
3.1 location and situation of test site
The test is selected to be carried out in the Yangjin area of Chongqing city. Paddy soil, pH6.8, organic matter content 1.8%.
3.2 test subjects and crops
Test subjects: chilo suppersalis (Walker)
And (3) test crops: rice (Q you No. 6)
3.3 weather data
The medicine is applied in the same day as yin and in northwest, 1.8 m/s, the highest temperature is 27, the lowest temperature is 22 and the average temperature is 24.5. During the test period, 14 rains are used, wherein 7-8-7-8 days of medium rain change into small rain, 11-11 days of medium rain change into large rain, 15-16-17 days of small rain change into medium rain, 18-19 days of thunderstorm rain change into medium rain, and 22 days of medium rain.
3.4 information of pesticide for preventing and treating other diseases and pests
No control of other pests was carried out during the test.
4 test design and arrangement
4.1 dosage and numbering of drugs
TABLE 3 test design of test agents
4.2 cell arrangement
4.2.1 cell arrangements
TABLE 4
| 1-1 | 6-2 | 5-3 | 2-4 |
| 3-1 | 1-2 | 6-3 | 6-4 |
| 5-1 | 3-2 | 2-3 | 4-4 |
| 6-1 | 2-2 | 3-3 | 3-4 |
| 2-1 | 4-2 | 4-3 | 1-4 |
| 4-1 | 5-2 | 1-3 | 5-4 |
4.2.2 cell area and repetition
Cell area: 30 square meters, and forming ridges between cells to prevent serial irrigation;
the number of repetitions: 4 times.
4.3 methods of application
4.3.1 administration periods and methods
Spraying the chilo suppressalis eggs in the incubation period.
4.3.2 applicator devices
PB-16 type knapsack hand sprayer.
4.3.3 application time and frequency
The application was carried out 7/4/2019, and only 1 application was carried out during the whole test period.
4.3.4 use amount
Spray treatment is carried out for 50L/mu.
4.4 investigation methods, times and times
4.4.1 investigation time and number of surveys
And (5) investigating after the blank control area is determined as harmful and fixed 20 days after the drug is applied.
4.4.2 methods of investigation
Every time parallel skip sampling is adopted, 50 clusters of rice are investigated in each cell, and the investigated spike number and the white spike number are recorded.
4.4.3 method for calculating drug efficacy
And (3) comparing whether the average control effect of each treatment has significant difference by adopting a new repolarization difference method.
4.5 direct effects on crops
In each survey, the marked plants were observed for phytotoxicity symptoms, and if so, the phytotoxicity symptoms and grades were recorded according to the following grading method.
-: no chemical injury;
+: mild phytotoxicity, no influence on the normal growth of crops;
++: obvious phytotoxicity, recoverability, no crop yield reduction,
+++: high phytotoxicity affects the normal growth of crops, causes certain loss on the yield and quality of the crops, and generally requires compensation of partial economic loss;
++++: severe phytotoxicity, hindered crop growth, severe crop yield and quality loss, economic losses should be compensated.
4.6 yield and quality of product
The consignor does not require it.
4.7 Effect on other organisms
During investigation, it was observed whether each treatment of the test agents had a significant effect on other organisms.
5 test results and analysis
Table 520% results of field efficacy test for preventing and treating rice-stem borer by using alpha-vitamin-chlorantraniliprole OD
Mean control effect analysis of variance for preventing and treating rice stem borer by using Odd (origin-destination-derived Dendroxybenzamide) OD (origin-destination-derived Dendroxyfen) with concentration of 620 percent
From the statistical results of the above table, it can be seen that:
5.120% of alpha-vitamin, chlorantraniliprole OD and a contrast medicament are respectively treated, the control effect on rice stem borers is that 20 days after the pesticide is respectively: 94.25% (45 g/ha), 90.65% (36 g/ha), 82.13% (27 g/ha), 80.43% (emamectin benzoate) and 90.57% (chlorantraniliprole). The control effect of each treatment of the test medicament is improved along with the increase of the dosage, and the control effect of 45 g/hectare treatment is higher than that of a control medicament emamectin benzoate and chlorantraniliprole; the control effect of 36 g/hectare treatment is higher than that of a contrast agent emamectin benzoate, and is equivalent to that of a contrast agent chlorantraniliprole; the control effect of 27 g/ha treatment was lower than that of 2 control agents.
5.2 results of the analysis of variance of the average control effect of each treatment show that the control effect difference of each treatment room reaches a significant level when 20% of the alphavims-chlorantraniliprole OD and the control agent are treated respectively, and the control effect difference is equivalent to the control agent chlorantraniliprole after the treatment of 36 g/hectare of the test agent 20d after the treatment.
5.3 No signs of plant damage were observed during each treatment.
5.4 treatment with each of the test agents had no significant effect on other organisms.
Conclusion 6
The test results show that 20% of the alpha-chlorantraniliprole OD provided by Shanghai Yuehie Biotech Co., Ltd has good control effect and no chemical injury by adopting spray treatment in the incubation period of the rice-stem borer eggs in 3 treatment doses. The recommended dosage of the product in the prevention and treatment of the rice stem borer is suggested as follows: the dosage of the active ingredients is 27-45 g/ha, and the dosage of the preparation is 9-15 ml/mu.
Secondly, preventing cabbage prodenia litura
3.1 location and situation of test site
The test was carried out in the Beibei polysaccharide region of Chongqing. Purple soil, pH6.8, organic matter content 1.8%.
3.2 test subjects and crops
Test subjects: prodenia litura: (Spodoptera litura (Fabricius))
And (3) test crops: cabbage (Jingfeng No. 1)
3.3 weather data
The medicine is applied in cloudy days, in northeast wind, the wind power is 0.8 m/s, the highest temperature is 25 ℃, the lowest temperature is 18 ℃, and the average temperature is 21.5 ℃.2 rains during the test period.
3.4 information of pesticide for preventing and treating other diseases and pests
No control of other pests was carried out during the test.
4 test design and arrangement
4.1 dosage and numbering of drugs
TABLE 7 test design of test agents
4.2 cell arrangement
4.2.1 cell arrangements
TABLE 8
| 3-1 | 5-2 | 6-3 | 4-4 |
| 2-1 | 1-2 | 3-3 | 5-4 |
| 4-1 | 2-2 | 5-3 | 2-4 |
| 6-1 | 4-2 | 7-3 | 6-4 |
| 1-1 | 3-2 | 1-3 | 7-4 |
| 5-1 | 7-2 | 2-3 | 1-4 |
| 7-1 | 6-2 | 4-3 | 3-4 |
4.2.2 cell area and repetition
Cell area: 20 square meters, and 1m protection rows are reserved among cells; the number of repetitions: 4 times.
4.3 methods of application
4.3.1 administration periods and methods
Spraying before 3 years old of cabbage prodenia litura.
4.3.2 applicator devices
PB-16 type knapsack hand sprayer.
4.3.3 application time and frequency
Day 21, 9/2019, 1 application throughout the test period.
4.3.4 use amount
50 liters per mu.
4.4 investigation methods, times and times
4.4.1 investigation time and number of surveys
The study was conducted before and 2d and 7d after the application.
4.4.2 methods of investigation
Five sampling methods are adopted, each cell is marked with 15 cabbages, and the number of live insects on the plants is investigated at a specified time.
4.4.3 method for calculating drug efficacy
And (3) comparing whether the average control effect of each treatment has significant difference by adopting a new repolarization difference method.
4.5 direct effects on crops
In each survey, the marked plants were observed for phytotoxicity symptoms, and if so, the phytotoxicity symptoms and grades were recorded according to the following grading method.
-: no chemical injury;
+: mild phytotoxicity, no influence on the normal growth of crops;
++: obvious phytotoxicity, recoverability, no crop yield reduction,
+++: high phytotoxicity affects the normal growth of crops, causes certain loss on the yield and quality of the crops, and generally requires compensation of partial economic loss;
++++: severe phytotoxicity, hindered crop growth, severe crop yield and quality loss, economic losses should be compensated.
4.6 Effect on other organisms
During investigation, it was observed whether each treatment of the test agents had a significant effect on other organisms.
5 test results and analysis
Table 920% Emamectin benzoate Chlorantraniliprole OD field efficacy test results for preventing cabbage prodenia litura
Mean control effect variance analysis of table 1020% emamectin benzoate-chlorantraniliprole OD for preventing and treating cabbage prodenia litura
From the statistical results of the above table, it can be seen that:
5.120% emamectin benzoate-chlorantraniliprole OD and a control agent are respectively treated, the control effect on cabbage prodenia litura is that 2d after the pesticide is respectively: 94.50% (36 g/ha), 90.63% (30 g/ha), 85.25% (24 g/ha), 90.19% (emamectin benzoate), 68.24% (chlorantraniliprole) and 74.80% (chlorfenapyr); 7d after the medicine is applied, the control effects of the medicines are respectively as follows: 98.32%, 94.15%, 90.73%, 95.31%, 75.70% and 80.25%. The control effect of each treatment of the test medicament is improved along with the increase of the dosage, and the 7d after the treatment is more than 2 d. The control effect of 36 g/hectare treatment is higher than that of 3 contrast agents, and the control effect of 30 g/hectare treatment is higher than that of the contrast agents, namely chlorantraniliprole and chlorfenapyr, and is basically equivalent to that of the contrast agent, namely emamectin benzoate; the control effect of 24 g/ha treatment is lower than that of the control medicament emamectin benzoate, but higher than that of the control medicaments chlorantraniliprole and chlorfenapyr.
5.2 results of the analysis of variance of the average control effect of each treatment show that the control effect change trends of the 20% emamectin benzoate-chlorantraniliprole OD and the control medicament after treatment are the same at 2d and 7d, namely the control effect difference of the rest of treatment rooms is at a significant level except that the difference between the treatment room of the test medicament of 30 g/hectare and the treatment room of the control medicament of emamectin benzoate is not significant.
5.3 No signs of plant damage were observed during each treatment.
5.4 treatment with each of the test agents had no significant effect on other organisms.
Conclusion 6
The test results show that 20% emamectin benzoate-chlorantraniliprole OD provided by Shanghai Yuejie Biotech company Limited can achieve good control effect and no chemical injury by adopting spray treatment at 3 treatment doses before 3 ages of cabbage prodenia litura. The recommended dosage of the product in the control of cabbage prodenia litura is recommended to be as follows: the dosage of the active ingredients is 24-36 g/ha, and the dosage of the preparation is 8-12 ml/mu.
The foregoing examples are illustrative only, and serve to explain some of the features of the present disclosure. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. And that advances in science and technology will result in possible equivalents or sub-substitutes not currently contemplated for reasons of inaccuracy in language representation, and such changes should also be construed where possible to be covered by the appended claims.
Claims (10)
1. An emamectin benzoate and chlorantraniliprole compound insecticidal composition is characterized in that the weight ratio of emamectin benzoate to chlorantraniliprole is 2: 1-1: 4; the preparation raw materials of the compound insecticidal composition also comprise alkoxylated tallow alcohol.
2. The emamectin benzoate and chlorantraniliprole compound insecticidal composition according to claim 1, wherein the amount of the alkoxylated tallow alcohol is at least 60 wt% of the weight of the emamectin benzoate.
3. The emamectin benzoate and chlorantraniliprole compound insecticidal composition as claimed in claim 2, wherein the dosage form of the compound insecticidal composition comprises dispersible oil suspending agent, seed coating agent, wettable powder and water dispersible granule.
4. The emamectin benzoate and chlorantraniliprole compound insecticidal composition as claimed in claim 3, wherein the dispersible oil suspending agent is prepared from 1-10 wt% of wetting dispersant, 0.5-5 wt% of thickener, 1-6 wt% of antifreezing agent and the balance of dispersing medium;
the preparation method of the dispersible oil suspending agent comprises the following steps:
according to the raw material component ratio, chlorantraniliprole, emamectin benzoate, alkoxylated tallow alcohol and wetting dispersant are subjected to high-speed shearing, mixed and dispersed, the medicine is ground under the action of mechanical energy, the medicine is sheared and broken into particles with the diameter less than 5 micrometers, then thickening agent, antifreezing agent and dispersing medium are added into a high-shear dispersing agent machine, and the dispersible oil suspending agent is obtained through shearing and mixing.
5. The emamectin benzoate and chlorantraniliprole compound insecticidal composition as claimed in any one of claims 1 to 4, wherein a preparation raw material of the compound insecticidal composition comprises an isosorbide derivative.
6. The emamectin benzoate and chlorantraniliprole compound insecticidal composition as claimed in claim 5, wherein the isosorbide derivative is compound A and/or compound B, and the compound A has the following structural formula:
wherein R is1Is an alkyl chain of C6-C16.
7. The emamectin benzoate and chlorantraniliprole compound insecticidal composition according to claim 6, wherein R is1Is a C8-C12 aliphatic alkyl chain.
8. The emamectin benzoate and chlorantraniliprole compound insecticidal composition as claimed in claim 6, wherein the compound B has the following structural formula:
wherein R is1Is an alkyl chain containing hydroxyl.
9. The emamectin benzoate and chlorantraniliprole compound insecticidal composition according to claim 8, wherein the alkyl chain containing the hydroxyl is-CH2CH(OH)OC(＝O)CH(＝CH2)CH3。
10. The emamectin benzoate and chlorantraniliprole compound insecticidal composition as claimed in any one of claims 1 to 9, is applied to rice insect pests.
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