CN111182907B - 用于治疗膀胱癌的abx196 - Google Patents

用于治疗膀胱癌的abx196 Download PDF

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Publication number
CN111182907B
CN111182907B CN201880064390.5A CN201880064390A CN111182907B CN 111182907 B CN111182907 B CN 111182907B CN 201880064390 A CN201880064390 A CN 201880064390A CN 111182907 B CN111182907 B CN 111182907B
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China
Prior art keywords
bladder
treatment
bladder cancer
abx196
antibody
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CN201880064390.5A
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Chinese (zh)
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CN111182907A (zh
Inventor
桑德琳·克拉伯
迪迪埃·席勒
哈特穆特·埃里希
菲利普·波莱蒂
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Wittycell
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Wittycell
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201880064390.5A 2017-09-13 2018-09-13 用于治疗膀胱癌的abx196 Active CN111182907B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17306182 2017-09-13
EP17306182.1 2017-09-13
PCT/EP2018/074778 WO2019053142A1 (en) 2017-09-13 2018-09-13 ABX196 FOR USE IN THE TREATMENT OF BLADDER CANCER

Publications (2)

Publication Number Publication Date
CN111182907A CN111182907A (zh) 2020-05-19
CN111182907B true CN111182907B (zh) 2023-01-06

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CN201880064390.5A Active CN111182907B (zh) 2017-09-13 2018-09-13 用于治疗膀胱癌的abx196

Country Status (18)

Country Link
US (1) US11266667B2 (https=)
EP (1) EP3681512B1 (https=)
JP (1) JP7214718B2 (https=)
KR (1) KR102706165B1 (https=)
CN (1) CN111182907B (https=)
AU (1) AU2018332046B2 (https=)
BR (1) BR112020004778A2 (https=)
CA (1) CA3075443A1 (https=)
CU (1) CU20200020A7 (https=)
DK (1) DK3681512T3 (https=)
ES (1) ES2893549T3 (https=)
HR (1) HRP20211351T1 (https=)
IL (1) IL273054B2 (https=)
MX (1) MX394216B (https=)
PL (1) PL3681512T3 (https=)
PT (1) PT3681512T (https=)
WO (1) WO2019053142A1 (https=)
ZA (1) ZA202001435B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117222414A (zh) 2021-03-01 2023-12-12 脱落性治疗公司 用于激活恒定自然杀伤t-细胞的化合物和用于消除炎性衰老细胞的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101917985A (zh) * 2007-12-05 2010-12-15 维迪瑟尔公司 糖基神经酰胺增强对抗原的免疫反应的用途
CN102215864A (zh) * 2008-10-08 2011-10-12 威蒂赛尔公司 用于抗流感的疫苗组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1197068A1 (en) * 2011-01-05 2015-01-02 台湾大学 Methods for preparation of glycosphingolipids and uses thereof
BR112019004906A2 (pt) 2016-09-14 2019-06-25 Abivax combinação incluindo abx196 para o tratamento de câncer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101917985A (zh) * 2007-12-05 2010-12-15 维迪瑟尔公司 糖基神经酰胺增强对抗原的免疫反应的用途
CN102215864A (zh) * 2008-10-08 2011-10-12 威蒂赛尔公司 用于抗流感的疫苗组合物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
A possible mechanism of intravesical BCG therapy for human bladder carcinoma: involvement of innate effector cells for the inhibition of tumor growth;Tomoe Higuchi;《Cancer Immunol Immunother》;20090112;第58卷(第8期);1245-1255 *
Efficacy of ABX196, a new NKT agonist, in prophylactic human vaccination;Josianne Nitcheu Tefit等;《Vaccine》;20140913;第32卷(第46期);6138-6145 *

Also Published As

Publication number Publication date
US20200230163A1 (en) 2020-07-23
RU2020109889A3 (https=) 2022-01-28
AU2018332046A1 (en) 2020-03-19
HRP20211351T1 (hr) 2021-11-26
JP2020533368A (ja) 2020-11-19
EP3681512B1 (en) 2021-08-04
CN111182907A (zh) 2020-05-19
ES2893549T3 (es) 2022-02-09
CA3075443A1 (en) 2019-03-21
WO2019053142A1 (en) 2019-03-21
US11266667B2 (en) 2022-03-08
EP3681512A1 (en) 2020-07-22
AU2018332046B2 (en) 2024-06-13
ZA202001435B (en) 2022-07-27
PL3681512T3 (pl) 2022-01-17
MX2020002812A (es) 2020-07-21
IL273054B1 (en) 2023-01-01
BR112020004778A2 (pt) 2020-10-13
JP7214718B2 (ja) 2023-01-30
KR20200102412A (ko) 2020-08-31
CU20200020A7 (es) 2020-11-30
DK3681512T3 (da) 2021-09-06
KR102706165B1 (ko) 2024-09-13
RU2020109889A (ru) 2021-09-06
PT3681512T (pt) 2021-10-06
MX394216B (es) 2025-03-24
IL273054A (en) 2020-04-30
IL273054B2 (en) 2023-05-01

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