CN111068016A - Lightyellow sophora root private nursing antibacterial gel and preparation method thereof - Google Patents

Lightyellow sophora root private nursing antibacterial gel and preparation method thereof Download PDF

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CN111068016A
CN111068016A CN202010052192.6A CN202010052192A CN111068016A CN 111068016 A CN111068016 A CN 111068016A CN 202010052192 A CN202010052192 A CN 202010052192A CN 111068016 A CN111068016 A CN 111068016A
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lightyellow sophora
sophora root
gel
root
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璧典附
赵丽
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention belongs to the technical field of gel preparation, and particularly relates to radix sophorae flavescentis private care antibacterial gel and a preparation method thereof. The traditional Chinese medicine composition comprises, by mass, 8-12 parts of radix sophorae flavescentis, 9-15 parts of dragon's blood, 8-10 parts of schisandra chinensis, 5-10 parts of golden cypress, 5-10 parts of fructus cnidii, 5-8 parts of dandelion, 5-7 parts of safflower, 4-9 parts of radix stemonae, 3-5 parts of madder, 0.1-0.3 part of borneol and 0.01-0.02 part of polyhexamethylene biguanide salt. The lightyellow sophora root private nursing antibacterial gel has a better antibacterial effect, improves the immunity of the organism, and has a better anti-inflammatory effect.

Description

Lightyellow sophora root private nursing antibacterial gel and preparation method thereof
Technical Field
The invention belongs to the technical field of gel preparation, and particularly relates to radix sophorae flavescentis private care antibacterial gel and a preparation method thereof.
Background
Under certain conditions, colloidal particles or macromolecules in a sol or solution are connected with each other to form a spatial network structure, and the structural voids are filled with a liquid (in a xerogel, a gas can be used, and the xerogel is also called an aerogel) serving as a dispersion medium, so that a special dispersion system is called a gel. It has no fluidity. The interior often contains a large amount of liquid. For example, the water content of blood gel and agar can reach more than 99%. It can be divided into elastic gels and brittle gels. The elastic gel loses its dispersion medium and then shrinks significantly in volume, and when the dispersion medium is resorbed, the volume expands again, such as gelatin and the like. Brittle gels do not change shape or volume when they lose or reabsorb the dispersion medium, e.g., silica gels and the like. The general gel is necessary to add a biological antibacterial agent so as to improve the performance of the gel.
Disclosure of Invention
The invention provides novel lightyellow sophora root private nursing antibacterial gel and a preparation method thereof.
In order to achieve the purpose, the specific technical scheme of the embodiment of the invention provides radix sophorae flavescentis private care antibacterial gel which is prepared from the following components, by mass, 8-12 parts of radix sophorae flavescentis, 9-15 parts of dragon's blood, 8-10 parts of schisandra chinensis, 5-10 parts of cortex phellodendri, 5-10 parts of fructus cnidii, 5-8 parts of dandelion, 5-7 parts of safflower, 4-9 parts of radix stemonae, 3-5 parts of madder, 0.1-0.3 part of borneol and 0.01-0.02 part of polyhexamethylene biguanide salt.
Further, the lightyellow sophora root private nursing antibacterial gel comprises 8 parts of lightyellow sophora root, 9 parts of dragon's blood, 8 parts of Chinese magnoliavine fruit, 5 parts of golden cypress, 5 parts of common cnidium fruit, 6 parts of dandelion, 5 parts of safflower, 4 parts of radix stemonae, 3 parts of madder, 0.1 part of borneol and 0.01 part of polyhexamethylene biguanide salt.
Further, the lightyellow sophora root private nursing antibacterial gel comprises 12 parts of lightyellow sophora root, 11 parts of dragon's blood, 8 parts of Chinese magnoliavine fruit, 8 parts of golden cypress, 6 parts of common cnidium fruit, 6 parts of dandelion, 5 parts of safflower, 5 parts of radix stemonae, 3 parts of madder, 0.2 part of borneol and 0.02 part of polyhexamethylene biguanide salt.
Further, the lightyellow sophora root private nursing antibacterial gel comprises 12 parts of lightyellow sophora root, 11 parts of dragon's blood, 8 parts of Chinese magnoliavine fruit, 8 parts of golden cypress, 6 parts of common cnidium fruit, 6 parts of dandelion, 5 parts of safflower, 5 parts of radix stemonae, 3 parts of madder, 0.2 part of borneol and 0.02 part of polyhexamethylene biguanide salt.
The embodiment of the invention also provides a method for preparing lightyellow sophora root private nursing antibacterial gel, which comprises the following steps of (1) decocting nine traditional Chinese medicines of lightyellow sophora root, dragon's blood, Chinese magnoliavine fruit, amur corktree bark, common cnidium fruit, dandelion, safflower, sessile stemona root and madder with 8 times and 6 times of distilled water for two times, wherein the distilled water is used for 2 hours for the first time and 1.5 hours for the second time, filtering respectively, and combining filtrates; (2) vacuum concentrating the above combined filtrates into fluid extract with relative density of about 1.05; (3) adding gel excipient into the above fluid extract, and making into gel in homogenizer; (4) sequentially adding borneol and polyhexamethylene biguanide, continuing homogenizing for half an hour, and vacuumizing.
Compared with the prior art, the invention has the beneficial effects that: the lightyellow sophora root private nursing antibacterial gel has a better antibacterial effect, improves the immunity of the organism, and has a better anti-inflammatory effect.
Detailed Description
In the description of the embodiments of the present invention, the meaning of "a plurality" means two or more unless otherwise specified. For example, a plurality of elements refers to two elements or more.
The term "and/or" herein is an association relationship describing an associated object, and means that there may be three relationships, for example, a display panel and/or a backlight, which may mean: there are three cases of a display panel alone, a display panel and a backlight at the same time, and a backlight alone. The symbol "/" herein denotes a relationship in which the associated object is or, for example, input/output denotes input or output.
In the embodiments of the present invention, words such as "exemplary" or "for example" are used to mean serving as examples, illustrations or descriptions. Any embodiment or design described as "exemplary" or "e.g.," an embodiment of the present invention is not necessarily to be construed as preferred or advantageous over other embodiments or designs. Rather, use of the word "exemplary" or "such as" is intended to present concepts related in a concrete fashion.
The specific technical scheme of the embodiment of the invention provides lightyellow sophora root private nursing antibacterial gel which is prepared from the following components, by mass, 8-12 parts of lightyellow sophora root, 9-15 parts of dragon's blood, 8-10 parts of Chinese magnoliavine fruit, 5-10 parts of amur corktree bark, 5-10 parts of common cnidium fruit, 5-8 parts of dandelion, 5-7 parts of safflower, 4-9 parts of radix stemonae, 3-5 parts of madder, 0.1-0.3 part of borneol and 0.01-0.02 part of polyhexamethylene biguanide salt.
Illustratively, the lightyellow sophora root private care antibacterial gel comprises 8 parts of lightyellow sophora root, 9 parts of dragon's blood, 8 parts of Chinese magnoliavine fruit, 5 parts of golden cypress, 5 parts of common cnidium fruit, 6 parts of dandelion, 5 parts of safflower, 4 parts of radix stemonae, 3 parts of madder, 0.1 part of borneol and 0.01 part of polyhexamethylene biguanide salt.
Illustratively, the lightyellow sophora root private care antibacterial gel comprises 12 parts of lightyellow sophora root, 11 parts of dragon's blood, 8 parts of Chinese magnoliavine fruit, 8 parts of golden cypress, 6 parts of common cnidium fruit, 6 parts of dandelion, 5 parts of safflower, 5 parts of radix stemonae, 3 parts of madder, 0.2 part of borneol and 0.02 part of polyhexamethylene biguanide salt.
Illustratively, the lightyellow sophora root private care antibacterial gel comprises 12 parts of lightyellow sophora root, 11 parts of dragon's blood, 8 parts of Chinese magnoliavine fruit, 8 parts of golden cypress, 6 parts of common cnidium fruit, 6 parts of dandelion, 5 parts of safflower, 5 parts of radix stemonae, 3 parts of madder, 0.2 part of borneol and 0.02 part of polyhexamethylene biguanide salt.
The other aspect of the embodiment of the invention also provides a method for preparing lightyellow sophora root private nursing antibacterial gel, which comprises the following steps of firstly weighing nine traditional Chinese medicines of lightyellow sophora root, dragon's blood, Chinese magnoliavine fruit, amur corktree bark, common cnidium fruit, dandelion, safflower, sessile stemona root and madder root which are used as components in the embodiment, decocting the nine traditional Chinese medicines with 8 times and 6 times of distilled water for two times, respectively filtering the nine traditional Chinese medicines for 2 hours for the first time and 1.5 hours for the second time, and merging filtrate; then vacuum concentrating the combined filtrate into clear paste with the relative density of about 1.05; adding gel excipient into the fluid extract, and making into gel in a homogenizer; then sequentially adding borneol and polyhexamethylene biguanide, continuing homogenizing for half an hour, and vacuumizing. And filling the prepared gel by a full-automatic gel filling machine, and packaging by 3.5g per piece.
Can be used for treating female genital pruritus, inflammation, nourishing, and removing odor; the gel prepared by the formula is used for cleaning two hands before sleeping at night, lying down, taking one side of the gel, removing a protective cap at the front end of the auxiliary device, pushing the gel to the deep part of the vagina, withdrawing the auxiliary device, and keeping the buttocks to stand upwards for 10-15 minutes.
It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
While embodiments of the present invention have been described, the present invention is not limited to the above-described embodiments, which are intended to be illustrative rather than limiting, and it will be apparent to those of ordinary skill in the art in light of the teachings of the present invention that many more modifications can be made without departing from the spirit and scope of the invention as defined in the appended claims.

Claims (5)

1. The lightyellow sophora root private nursing antibacterial gel is characterized in that: the traditional Chinese medicine composition comprises, by mass, 8-12 parts of radix sophorae flavescentis, 9-15 parts of dragon's blood, 8-10 parts of schisandra chinensis, 5-10 parts of golden cypress, 5-10 parts of fructus cnidii, 5-8 parts of dandelion, 5-7 parts of safflower, 4-9 parts of radix stemonae, 3-5 parts of madder, 0.1-0.3 part of borneol and 0.01-0.02 part of polyhexamethylene biguanide salt.
2. The lightyellow sophora root private care bacteriostatic gel according to claim 1, which is characterized in that: comprises 8 parts of lightyellow sophora root, 9 parts of dragon's blood, 8 parts of Chinese magnoliavine fruit, 5 parts of amur corktree bark, 5 parts of common cnidium fruit, 6 parts of dandelion, 5 parts of safflower, 4 parts of sessile stemona root, 3 parts of madder root, 0.1 part of borneol and 0.01 part of polyhexamethylene biguanide salt.
3. The lightyellow sophora root private care bacteriostatic gel according to claim 1, which is characterized in that: comprises 12 parts of lightyellow sophora root, 11 parts of dragon's blood, 8 parts of Chinese magnoliavine fruit, 8 parts of amur corktree bark, 6 parts of common cnidium fruit, 6 parts of dandelion, 5 parts of safflower, 5 parts of sessile stemona root, 3 parts of madder root, 0.2 part of borneol and 0.02 part of polyhexamethylene biguanide salt.
4. The lightyellow sophora root private care bacteriostatic gel according to claim 1, which is characterized in that: comprises 12 parts of lightyellow sophora root, 11 parts of dragon's blood, 8 parts of Chinese magnoliavine fruit, 8 parts of amur corktree bark, 6 parts of common cnidium fruit, 6 parts of dandelion, 5 parts of safflower, 5 parts of sessile stemona root, 3 parts of madder root, 0.2 part of borneol and 0.02 part of polyhexamethylene biguanide salt.
5. A method for preparing the lightyellow sophora root private care bacteriostatic gel of any one of claims 1 to 4, which is characterized by comprising the following steps: the preparation method comprises the following steps of (1) decocting nine traditional Chinese medicines of radix sophorae flavescentis, dragon's blood, schisandra chinensis, golden cypress, fructus cnidii, dandelion, safflower, radix stemonae and madder with 8 times and 6 times of distilled water respectively twice, wherein the first time is 2 hours, the second time is 1.5 hours, filtering respectively, and combining filtrates; (2) vacuum concentrating the above combined filtrates into fluid extract with relative density of about 1.05; (3) adding gel excipient into the above fluid extract, and making into gel in homogenizer; (4) sequentially adding borneol and polyhexamethylene biguanide, continuing homogenizing for half an hour, and vacuumizing.
CN202010052192.6A 2020-01-17 2020-01-17 Lightyellow sophora root private nursing antibacterial gel and preparation method thereof Pending CN111068016A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112263667A (en) * 2020-10-15 2021-01-26 李利发 Traditional Chinese medicine biological preparation for health of female genital tract and preparation method thereof
CN113425693A (en) * 2021-07-01 2021-09-24 西安浩然药业有限责任公司 Formula and preparation method of gynecological effervescent tablets

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Publication number Priority date Publication date Assignee Title
CN107683869A (en) * 2017-09-12 2018-02-13 吴晓军 A kind of biological bacteriostatic gel
CN107875264A (en) * 2017-11-21 2018-04-06 佛山微赢电子商务有限公司 A kind of privates nursing bacteriostatic gel and preparation method thereof
CN109602695A (en) * 2019-01-28 2019-04-12 拍合尔尼萨·吐尔孙 A kind of production method of bacteriostatic gel
CN109876051A (en) * 2019-04-29 2019-06-14 广东触爱生物医药有限公司 A kind of gynecological gel and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107683869A (en) * 2017-09-12 2018-02-13 吴晓军 A kind of biological bacteriostatic gel
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Application publication date: 20200428