CN1110565A

CN1110565A - Anti-thristy melbine capsule and its production method

Info

Publication number: CN1110565A
Application number: CN 94103531
Authority: CN
Inventors: 梁清吉
Original assignee: Individual
Current assignee: Individual
Priority date: 1994-04-21
Filing date: 1994-04-21
Publication date: 1995-10-25

Abstract

The method for producing capsule for curing diabetes mellitus by effectively regulating metabolism and increasing immunity features use of trace elements along with Chinese-medicinal materials.

Description

Anti-thristy melbine capsule and its production method

The present invention relates to a kind of capsule and production method thereof for the treatment of diabetes.

At present, the oral diamicron of the general employing of treatment diabetes, glibenclamide tablet and transfusion filling insulin etc. are though play certain therapeutical effect to diabetics, but can not eradicate, diabetics generally shows as the dryness of the lung, gastric heat, suffer from a deficiency of the kidney, and the treatment still be limited to " control the person of disappearing, its lung of Yi Run; The person of disappearing in controlling, suitable clear its stomach; Control the inferior the person of disappearing, should grow its kidney " Chinese medicine that adopts is generally the Radix Astragali, the Radix Rehmanniae, pollen, Herba Dendrobii.Another symptom of diabetes is polydipsia, polyphagia, polyuria, loses weight, the initial stage patient Yin bivacuity that generally feels cold, scorching flourishing, the hepatic and renal YIN deficiency, the course of disease is than the elder and then numb hand and foot occurs, it is weak to become thin, dizzy cardiopalmus, visual deterioration or cataract occurs, retinopathy, menoxenia or amenorrhea, sexual impotence, just secrete or symptom such as diarrhoea, so diabetes are arch enemies of man, people are being devoted to seek a kind of effective pharmaceutical methods that effects a radical cure diabetes always, do not have the precedent of success so far.

Purpose of the present invention is exactly to adopt at the deficiency of existing treatment diabetes medicament and method:

The Chinese medicine that increases a large amount of blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, the eliminating stagnation of regulating the flow of vital energy improves whole metabolic cycles, prevents the complication such as complex of blood stasis, sugar.

Mechanism of the present invention: according to modern medicine to physiology, pathological observation, 70-80% does not have the variation on the pathological anatomy in the diabetes human body, in many clinically cases, human body (comprising pancreatic tissue) inner blood viscosity increased, the appearance blood stasis that has, even generation thromboembolism phenomenon, in addition, contain sugar in diabetes patient's blood and increase, the complex that sugar can occur is deposited in the human capillary vessel, in the course of time, the people knows from experience, and the degeneration of cell fibrosis takes place, owing to be confined to the viewpoint of three types of diabetes, so the often merely difference of three types of diabetes in diagnosis and treatment, and when having ignored clearing away heat and nourishing YIN, add the product of helping blood circulation promoting and blood stasis dispelling.For this reason, long to the course of disease, long life has the patient of complication should increase blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, the medicine of the eliminating stagnation of regulating the flow of vital energy, as, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Ginseng etc., improve whole metabolic cycles, the complication such as complex that prevent blood stasis, thromboembolism and sugar occur, and could fundamentally reach the purpose of control and healing diabetes from integral body like this.

With addition of with the human body trace elements necessary.

We obtain important new progress to the research of trace element and diabetes; it is new problems that we propose that trace element can be prevented and treated diabetes; the new theory viewpoint; studies show that: micro elements needed by human ferrum; zinc; the metabolism of copper is relevant with diabetes; diabetes are pancreatic excreting insulin functional disorders and causing; the pancreatic surface is the film that is made of a large amount of multiple proteins; to protect and to keep the 26S Proteasome Structure and Function of pancreatic; the special albumen that trace element participates in the pancreatic surface synthesizes; this albumen is called " Glut-2 " protein; and " Glut-2 " protein can promote insulin secretion; glucose in the blood is delivered to the pancreas beta cell, thereby blood sugar content is descended.Discover: micro elements needed by human (Fe, Zn, Cu) be the conduction mediator of nervus centralis, its ion evenly distributes with strand and multichain form respectively systematically along nerve fiber in human body, contain a certain amount of trace element between the neuron, mitochondrion is prominent to be steeped etc., form the electron density district, it is regulated by the sympathetic nerve of nervus centralis and parasympathetic nervous that secretion of insulin is regulated, hypothalamus has the maincenter of regulating insulin secretion among the central nervous system, electricity irritation hypothalamus ventral lateral nucleus, insulin secretion is increased, for this reason, " anti-thristy melbine capsule " increases micro elements needed by human Fe, Zn, Cu.

Prescription of the present invention is (is unit of weight with the gram): Radix Astragali 16-24, pollen 16-24, Rhizoma Anemarrhenae 16-24, Herba Dendrobii 8-12, female ginseng 18-24, Rhizoma Chuanxiong 18-24, Rhizoma Coptidis 6-8.Fu Cen 6-8, Rhizoma Alismatis 6-9, Rhizoma Atractylodis Macrocephalae 8-12, Margarita powder 0.2-0.6, Colla Corii Asini powder 2-4, Radix Rehmanniae 8-12, Radix Ginseng 6-8, Rhizoma Pinelliae 6-8, the trace element of adding is (is unit of weight with the milligram) zinc sulfate 260-340, ferrous sulfate 550-650, copper sulfate 45-55.

Technology of the present invention is:

1, with the Radix Astragali, pollen, the Rhizoma Anemarrhenae, Herba Dendrobii, female ginseng, Rhizoma Chuanxiong, Rhizoma Coptidis, Poria, Rhizoma Alismatis, the Rhizoma Atractylodis Macrocephalae, the Radix Rehmanniae take by weighing by proportioning and mix, under 35-42 ℃ of condition, use distilled water extraction, extracting solution is distilled under 95-100 ℃ of condition, with the ethanol precipitate with ethanol of distillate with 85-95%, remove ethanol then, the liquid of this moment is the runny plaste shape, and then drying is made dried cream about 110 ℃, dried cream powder is broken and in 80 mesh sieves screenings, and be powder A this moment;

2, Radix Ginseng, Colla Corii Asini, Margarita, the Rhizoma Pinelliae, zinc sulfate, ferrous sulfate, copper sulfate are pulverized 80 mesh sieves, made dry powder B;

3, powder A and dry powder B are mixed adding starch, adjuvants such as Pulvis Talci stir, and are finished product, with the finished product packing, make capsule.

Embodiments of the invention see Table, and mark all is not unit with g:

Real

Become to execute 123

Part example

The Radix Astragali 16 20 24

Pollen 16 20 24

The Rhizoma Anemarrhenae 16 20 24

Herba Dendrobii 8 10 12

Radix Salviae Miltiorrhizae 18 21 24

Rhizoma Chuanxiong 18 21 24

Rhizoma Coptidis 678

Fu Cen 678

Rhizoma Alismatis 678

The Rhizoma Atractylodis Macrocephalae 8 10 12

Margarita 0.2 0.4 0.6

Colla Corii Asini powder 234

The Radix Rehmanniae 8 10 12

Radix Ginseng 678

The Rhizoma Pinelliae 678

Zinc sulfate (mg) 260 300 340

Ferrous sulfate (mg) 550 600 650

Copper sulfate (mg) 45 50 55

Present embodiment technology is the same.

The present invention can regulate the metabolic function of human body effectively, improves autoimmunity, and this medical instrument has: the function of promoting the production of body fluid to quench thirst, clearing heat and moistening dryness, replenishing QI to invigorate the spleen, enriching yin and nourishing kidney, blood circulation promoting and blood stasis dispelling.Example is observed surplus clinical 3000, and effective percentage reaches 82%.

Claims

1, a kind of anti-thristy melbine capsule, its prescription is (mark is not a unit with the gram): Radix Astragali 16-24, pollen 16-24, Rhizoma Anemarrhenae 16-24, Herba Dendrobii 8-12, female ginseng 18-24, Rhizoma Chuanxiong 18-24, Rhizoma Coptidis 6-8, Poria 6-8, Rhizoma Alismatis 6-9, Rhizoma Atractylodis Macrocephalae 8-12, Margarita powder 0.2-0.6, Colla Corii Asini powder 2-4, Radix Rehmanniae 8-12, Radix Ginseng 6-8, Rhizoma Pinelliae 6-8, the trace element that adds is (is unit of weight with the milligram) zinc sulfate 260-340, ferrous sulfate 550-650, copper sulfate 45-55.

2, the anti-thristy melbine capsule production method is with the Radix Astragali, pollen, the Rhizoma Anemarrhenae, Herba Dendrobii, female ginseng, Rhizoma Chuanxiong, Rhizoma Coptidis, Poria, Rhizoma Alismatis, the Rhizoma Atractylodis Macrocephalae, the Radix Rehmanniae take by weighing by proportioning and mix, under 35-42 ℃ of condition, use distilled water extraction, extracting solution is distilled under 95-100 ℃ of condition, with the ethanol precipitate with ethanol of distillate with 85-95%, remove ethanol then, the liquid of this moment is the runny plaste shape, and then drying is made dried cream about 110 ℃, dried cream powder is broken and in 80 mesh sieves screenings, and be powder A this moment;

Radix Ginseng, Colla Corii Asini, Margarita, the Rhizoma Pinelliae, zinc sulfate, ferrous sulfate, copper sulfate are pulverized 80 mesh sieves, made dry powder B;

Powder A and dry powder B are mixed adding starch, and adjuvants such as Pulvis Talci stir, and are finished product, with the finished product packing, make capsule.