CN111053160A - Microbial mixed medicament for preventing piglet diarrhea - Google Patents

Microbial mixed medicament for preventing piglet diarrhea Download PDF

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Publication number
CN111053160A
CN111053160A CN201911225471.1A CN201911225471A CN111053160A CN 111053160 A CN111053160 A CN 111053160A CN 201911225471 A CN201911225471 A CN 201911225471A CN 111053160 A CN111053160 A CN 111053160A
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China
Prior art keywords
piglets
intestinal
microbial
cfu
antibiotics
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Pending
Application number
CN201911225471.1A
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Chinese (zh)
Inventor
郑雪媚
张文
方文棋
刘宗新
吴阳开
蒋顺进
黄炜乾
张泳
唐谢芳
林万华
何海峰
贾元斌
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Guangdong Rongda Biology Co ltd
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Guangdong Rongda Biology Co ltd
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Application filed by Guangdong Rongda Biology Co ltd filed Critical Guangdong Rongda Biology Co ltd
Priority to CN201911225471.1A priority Critical patent/CN111053160A/en
Publication of CN111053160A publication Critical patent/CN111053160A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/195Antibiotics

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Birds (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a microbial mixed medicament for preventing piglet diarrhea. Harmful strains in intestinal tracts of piglets are removed through the enterobacter faecium, the bacillus subtilis, the clostridium butyricum and the bacillus licheniformis, so that the intestinal health of the piglets is maintained, then the excessive growth of the strains is inhibited through the combined action of the fructooligosaccharide and the antibacterial peptide, and the intestinal injury is repaired, so that the balance of intestinal flora is maintained, and through experiments in an experimental pig farm, the scheme effectively replaces antibiotics to prevent the diarrhea of the piglets, so that the piglets are prevented from being damaged by the side effect of the antibiotics in the growth process, and grow healthier.

Description

Microbial mixed medicament for preventing piglet diarrhea
Technical Field
The invention relates to the field of microbial medicaments, in particular to a microbial mixed medicament for preventing piglet diarrhea.
Background
At present, no effective solution exists in production, antibiotics can be added into the daily ration of most weaned piglets for prevention, or zinc oxide with the pharmacological dose of 2500-4000mg/kg (the highest addition amount of 1600ppm specified in the state at present) is used in the daily ration for prevention and treatment, or antibiotics are injected to treat diarrhea piglets (cephalosporin + gentamia + andrographis paniculata, etc.), so that the piglets are stressed, and the antibiotics are easy to cause intestinal flora disorder and drug resistance. With increasing awareness, it has been recognized that the abuse of antibiotics will lead to public food safety issues. Growth-promoting antibiotics are proposed in European countries as early as 1986, a plurality of countries in European Union continue to implement the growth-promoting antibiotics, and the national agricultural and rural announcements will completely forbid the addition of feed antibiotics in the feed to promote the growth of animals by 2020 so as to ensure the sustainable development of the livestock industry in China and find an efficient and green antibiotic substitute.
Disclosure of Invention
In order to solve the above technical problems, the present invention aims to provide a mixed medicament prepared from microorganisms for preventing diarrhea of piglets.
The scheme adopted by the invention for solving the problems is as follows: a microbial mixed medicament for preventing piglet diarrhea is characterized in that: the mixed medicament is a mixture of antibacterial peptide, enterobacter faecium, bacillus subtilis, clostridium butyricum, bacillus licheniformis, fructo-oligosaccharide and additives.
As a further improvement of the technical proposal, the number of the enterobacter faecium is 1x107cfu/g。
As a further improvement of the technical proposal, the number of the bacillus subtilis is 1x109cfu/g。
As a further improvement of the technical scheme, the number of the clostridium butyricum is 1x108cfu/g。
As a further improvement of the technical scheme, the number of the first bacillus is 1x109cfu/g。
As a further improvement of the technical proposal, the weight percentage of the fructo-oligosaccharide is 30-40%.
As a further improvement of the technical scheme, the fruit oligosaccharide is extracted from jerusalem artichoke.
The beneficial effect of this scheme is: the intestinal health of piglets is maintained by clearing away harmful strains in intestinal tracts of piglets through the enterobacter faecium, the bacillus subtilis, the clostridium butyricum and the bacillus licheniformis, and then the excessive growth of the strains is inhibited and the intestinal damage is repaired under the combined action of the fructooligosaccharide and the antibacterial peptide, so that the balance of intestinal flora is maintained.
Detailed Description
A microbial mixed medicament for preventing piglet diarrhea is a mixture of antibacterial peptide, enterobacter faecium, bacillus subtilis, clostridium butyricum, bacillus licheniformis, fructo-oligosaccharide and additives.
Harmful strains in intestinal tracts of piglets are removed through the enterobacter faecium, the bacillus subtilis, the clostridium butyricum and the bacillus licheniformis, so that the intestinal health of the piglets is maintained, then the excessive growth of the strains is inhibited through the combined action of the fructooligosaccharide and the antibacterial peptide, and the intestinal injury is repaired, so that the balance of intestinal flora is maintained, and through experiments in an experimental pig farm, the scheme effectively replaces antibiotics to prevent the diarrhea of the piglets, so that the piglets are prevented from being invaded by the side effect of the antibiotics in the growth process, and grow healthier.
In a further improvement, the number of the enterobacter faecium is preferably 1x107cfu/g. The number of the bacillus subtilis is preferably 1x109cfu/g. The number of the clostridium butyricum is preferably 1x108cfu/g. The number of the first bacillus is preferably 1x109cfu/g。
In a further improvement, the weight ratio of the fructo-oligosaccharide is preferably 30-40%. In view of cost, the oligo-saccharides are preferably extracted from jerusalem artichoke, thereby greatly reducing the cost.
The above is only a preferred embodiment of the present invention, and not intended to limit the scope of the present invention, and all equivalent structural changes made by using the content of the present specification, or directly or indirectly applied to other related technical fields, under the inventive concept of the present invention, are included in the scope of the present invention.

Claims (7)

1. A mixed microbial medicament for preventing piglet diarrhea is characterized in that: the medicament is a mixture of antibacterial peptide, enterobacter faecium, bacillus subtilis, clostridium butyricum, bacillus licheniformis, fructooligosaccharide and additives.
2. The microbial cocktail of claim 1 wherein said mixture comprises:
the number of the enterobacter faecium is 1x107cfu/g。
3. The microbial cocktail of claim 1 wherein said mixture comprises:
the number of the bacillus subtilis is 1x109cfu/g。
4. The microbial cocktail of claim 1 wherein said mixture comprises:
the number of the clostridium butyricum is 1x108cfu/g。
5. The microbial cocktail of claim 1 wherein said mixture comprises:
the number of the first bacillus is 1x109cfu/g。
6. The microbial cocktail of claim 1 wherein said mixture comprises:
the weight ratio of the fructo-oligosaccharide is 30-40%.
7. The microbial cocktail of claim 1 wherein said mixture comprises:
the oligo saccharide is extracted from Jerusalem artichoke.
CN201911225471.1A 2019-12-04 2019-12-04 Microbial mixed medicament for preventing piglet diarrhea Pending CN111053160A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911225471.1A CN111053160A (en) 2019-12-04 2019-12-04 Microbial mixed medicament for preventing piglet diarrhea

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911225471.1A CN111053160A (en) 2019-12-04 2019-12-04 Microbial mixed medicament for preventing piglet diarrhea

Publications (1)

Publication Number Publication Date
CN111053160A true CN111053160A (en) 2020-04-24

Family

ID=70299703

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201911225471.1A Pending CN111053160A (en) 2019-12-04 2019-12-04 Microbial mixed medicament for preventing piglet diarrhea

Country Status (1)

Country Link
CN (1) CN111053160A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102613409A (en) * 2012-03-30 2012-08-01 武汉回盛生物科技有限公司 Feed additive for controlling newborn pig diarrhea
CN105211638A (en) * 2014-05-26 2016-01-06 瑞普(天津)生物药业有限公司 A kind of probiotics of prevention and therapy breast piglet bacillary diarrhoea
WO2016174485A1 (en) * 2015-04-28 2016-11-03 Alpha- Vet Állatgyógyászati Kft. Feed supplement additive
CN106490369A (en) * 2016-12-14 2017-03-15 深圳市前海金卓生物技术有限公司 Pig starter feed core material

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102613409A (en) * 2012-03-30 2012-08-01 武汉回盛生物科技有限公司 Feed additive for controlling newborn pig diarrhea
CN105211638A (en) * 2014-05-26 2016-01-06 瑞普(天津)生物药业有限公司 A kind of probiotics of prevention and therapy breast piglet bacillary diarrhoea
WO2016174485A1 (en) * 2015-04-28 2016-11-03 Alpha- Vet Állatgyógyászati Kft. Feed supplement additive
CN106490369A (en) * 2016-12-14 2017-03-15 深圳市前海金卓生物技术有限公司 Pig starter feed core material

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Application publication date: 20200424