CN111012870A - Vibration-damping medicine - Google Patents
Vibration-damping medicine Download PDFInfo
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- CN111012870A CN111012870A CN201811213368.0A CN201811213368A CN111012870A CN 111012870 A CN111012870 A CN 111012870A CN 201811213368 A CN201811213368 A CN 201811213368A CN 111012870 A CN111012870 A CN 111012870A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
- A61K36/515—Gentiana
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating Parkinson's disease, which is prepared from the following raw materials: prepared rhizome of rehmannia, Chinese angelica, white peony root, asarum, gastrodia tuber, clematis root, mistletoe, gentian, rhubarb, prepared pinellia tuber and other 17 kinds of Chinese medicinal materials and prepared into bolus or decoction for oral administration. Parkinson's disease belongs to the field of paralysis agitans of traditional Chinese medicine, and is manifested by the main clinical symptoms of head shaking, involuntary tremor of limbs, muscle stiffness, gait and posture disorder and the like. The traditional Chinese medicine considers that: "all the tendons and vessels can not be restricted, which belongs to the wind condition". It is considered that the deficiency of yin and blood is the main cause and the wind-fire cannot be stopped, so it is difficult to treat any syndrome. Western medicine considers that the disease is a common nervous system disease, the disease is caused by the decrease of dopamine content in the substantia nigra, a black nucleus in the midbrain, and the imbalance of acetylcholine function, and the currently applied treatment means can only improve symptoms, cannot prevent the development of the disease, and cannot cure the disease. The invention has the functions of tonifying liver and kidney, calming liver wind, benefiting qi and nourishing blood, reducing phlegm and removing blood stasis and removing dampness, so the clinical treatment effect is good, the cure rate can reach more than 95 percent, and the effective rate is 100 percent.
Description
The invention belongs to the technical field of traditional Chinese medicine preparation for treating Parkinson's disease.
Secondly, the Parkinson disease belongs to the field of paralysis agitans in the traditional Chinese medicine, the main symptoms are static tremor, involuntary tremor of limbs, muscle stiffness, gait disorder such as posture disturbance, dull eyes, choking cough caused by drinking water and the like, and the traditional Chinese medicine considers that the muscles and the vessels can not be restrained and the symptoms belong to wind symptoms. It is considered that the disease is rare in the middle-aged and more frequent in the elderly. Mainly due to deficiency of yin and blood and incapability of stopping wind-fire, the disease is difficult to treat in any syndrome, and is considered as a common nervous system pathological change by western medicine, which is caused by the fact that the content of dopamine in a black nucleus in midbrain, namely substantia nigra is reduced, and the dopamine reduction and acetylcholine function are unbalanced to cause disease, namely the manifestation of Parkinson's disease. The currently applied treatment means only improves symptoms, cannot prevent the progress of the disease, and cannot cure the disease, and the symptoms of the late disease cannot be controlled due to poor response of the patient to the medicine, so that the patient may be stiff, cannot take care of himself in life, even lies in bed for a long time, and finally dies of complications such as pneumonia.
The Chinese medicine 'plain questions, essential theory of truth' is recorded: wind-cold syndrome all belongs to the liver, and spasm and strong neck syndrome all belongs to dampness. The "rope is accurately measured by the syndrome method, miscellaneous diseases" is recorded: "quiver, shake too; vibration, oscillation "is also" used. The tendons and vessels are not restrained and can be sustained, and the wind is like.
The invention relates to a traditional Chinese medicine preparation for treating Parkinson's disease, which is prepared from the following raw materials: 17 traditional Chinese medicines of prepared rhizome of rehmannia, radix astragali, large-leaved gentian, angelica, szechuan lovage rhizome, white paeony root, divaricate saposhnikovia root, tall gastrodia tuber, clematis root, largehead atractylodes rhizome, parasitic gentian, rhubarb and prepared pinellia tuber and safflower are prepared according to a metering ratio and decocted in water or prepared into various dosage forms for oral administration.
Parkinson's disease, the etiology and pathogenesis of paralysis agitans, is mainly the deficiency of the principal and secondary aspects, deficiency of liver yin and kidney yin, malnutrition of the tendons and vessels, and consumption of essence and blood, which leads to water retention, endogenous wind-yang stirring, and uprush of wood fire, leading to shaking of the head and body and tremor. The disease is caused by deficiency of both qi and blood and failure of blood to nourish the tendons. Moreover, liver and kidney yin deficiency produces heat and wind, while qi deficiency produces blood stasis and phlegm. In addition, depression of the emotion and transformation of five emotions into fire induce pathogenic wind, fire, phlegm and blood stasis due to deficiency to affect the nourishing and nourishing of the tendons and vessels by yin and blood, so the deficiency is liver-kidney yin deficiency, qi-blood deficiency and heart deficiency; the secondary excess is wind, phlegm, fire and stasis. And when the mind fails to function, the head shakes, the limbs vibrate or spasm.
The invention has the effects of nourishing liver and kidney, benefiting qi and nourishing blood, calming liver and calming wind, reducing phlegm, removing blood stasis and dehumidifying. Wherein: radix Dipsaci with parasitic effect in warming earth is used as the monarch drug for nourishing liver and kidney. Gastrodia elata, white peony root, divaricate saposhnikovia root, radix paeoniae alba, radix astragali, angelica sinensis, white peony root, radix angelicae sinensis, white peony root, radix astragali, radix angelicae sinensis, white peony root, radix angelicae sinensis, radix paeoniae alba, qi and blood are ministerial drugs, and other drugs are adjuvant drugs for promoting blood circulation, removing blood stasis. The medicines have the effects of tonifying liver and kidney, calming liver and calming wind, tonifying qi and nourishing blood, reducing phlegm and removing blood stasis and removing dampness, so the clinical curative effect is good.
The traditional Chinese medicine preparation can effectively treat the Parkinson's disease, and obtains excellent curative effect after years of clinical practice application to men, women and 100 patients of all ages, wherein the cure rate can reach more than 95 percent, or: none of the cases of adherence to treatment is cured. Several cases are listed as follows:
the medical record 1 ran a certain woman, 47 years old, Taiping sugarcane fort in the longevity district of Chongqing city. In 1997, day 21 and 6 months, the doctor visited the clinic and found that the patients had involuntary tremor of their limbs, head shaking, gait and posture disorders, and dull eyes. Patient at the time of patient study: the patient is diagnosed as the Parkinson's disease through hospital examination, the effect of taking western medicines in western medicine is not obvious for a long time, and the effect of taking traditional Chinese medicines in a short time is not obvious, so that the patient can be particularly found for diagnosis and treatment today. I take the drug for relieving shock of the invention by water decoction, and take the drug continuously for one month to cure the disease.
2. some certain leaf, woman, 80 years old, live in four groups of the longevity district of Chongqing, boat town dragon village. I see the clinic for 3/19 days 1998. Patient complaints are: "Tremor hands, shaking head, have been examined by hospital for more than 2 years, confirmed to be Parkinson's disease, and ineffective treatment by Western medicine, so you are seeing the disease today and take the medicine". I use the drug of the invention to give patients, and take the drug by water decoction, and cure the disease after continuously taking the drug for one month.
The medical record 3, chapter one, man, 68 years old, live in the middle way of the street and phoenix in the long-lived area of Chongqing city. In 2008, 28 days 5 and month, I visit my clinic. Patient complaints are: "tremor, emaciation, waist distension, urine with yellow urine, dry stool, confirmed diagnosis of Parkinson disease by hospital examination". Pale with cracks in the middle, wiry and thready pulse, 72 pulses per minute. The invention is taken as pills, and the disease can be cured after the pill is taken for 2 months.
The medical record 4, xu a certain, male, 72 years old, live in the famous garden of the city of phoenix city in the longevity district of Chongqing city. In 2012, day 2, month 18, I am in the clinic to see illness. Patient complaints are: ' the resting tremor of the right hand is half a year, the parkinsonism is diagnosed in hospital examination, the multi-party treatment is ineffective, and the doctor can hear and say that you can cure the disease, so that the doctor can be specially found to see the disease and can cure the disease. I say that: "people can cure the disease if they take the medicine with patience and have a good mood. Therefore, the medicine for calming the earthquake is taken as pills, and the patient is cured after taking the medicine for 40 days.
The specific implementation mode comprises the following raw material medicines: 30 parts of Chinese angelica, ligusticum wallichii, radix sileris, rhizoma gastrodiae, radix clematidis and pinellia ternate respectively are subjected to heat treatment, 12 parts of gentian, 12 parts of rhubarb, 9 parts of octyl safflower and 6 parts of powder are subjected to heat treatment, honey is taken as a pill, and the pill is large in phoenix tree seed, 3 times a day, and 15g of warm boiled water is taken at an empty stomach. Or according to different requirements of patients, the dosage of the original prescription is increased or decreased according to the proportion, and the medicine is prepared into different dosage forms, such as powder, decoction and the like, for oral administration.
Claims (2)
1. A traditional Chinese medicine preparation for treating Parkinson's disease is characterized in that: the raw material medicines comprise 30 parts of Chinese angelica, szechuan lovage rhizome, tall gastrodia tuber, large-head gentian root, himalayan teasel root and Chinese taxillus rhizome, 20 parts of asarum, 6 parts of gentian, 12 parts of rhubarb, 10 parts of safflower and 6 parts by weight.
2. The traditional Chinese medicine preparation for treating Parkinson's disease according to claim 1, which is characterized in that: the raw materials are proportionally increased or decreased according to the dosage of the original prescription, and are prepared into different dosage forms for oral administration according to different requirements.
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CN201811213368.0A CN111012870A (en) | 2018-10-10 | 2018-10-10 | Vibration-damping medicine |
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CN201811213368.0A CN111012870A (en) | 2018-10-10 | 2018-10-10 | Vibration-damping medicine |
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CN201811213368.0A Withdrawn CN111012870A (en) | 2018-10-10 | 2018-10-10 | Vibration-damping medicine |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111686209A (en) * | 2020-07-10 | 2020-09-22 | 尧舜泽生物医药(南京)有限公司 | Traditional Chinese medicine compound preparation for treating Parkinson's disease and preparation method and application thereof |
CN117442687A (en) * | 2023-11-13 | 2024-01-26 | 沈阳君弘医药科技有限公司 | Traditional Chinese medicine composition for treating parkinsonism and application thereof |
-
2018
- 2018-10-10 CN CN201811213368.0A patent/CN111012870A/en not_active Withdrawn
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111686209A (en) * | 2020-07-10 | 2020-09-22 | 尧舜泽生物医药(南京)有限公司 | Traditional Chinese medicine compound preparation for treating Parkinson's disease and preparation method and application thereof |
CN117442687A (en) * | 2023-11-13 | 2024-01-26 | 沈阳君弘医药科技有限公司 | Traditional Chinese medicine composition for treating parkinsonism and application thereof |
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Application publication date: 20200417 |