CN110998316A

CN110998316A - Sensing cup

Info

Publication number: CN110998316A
Application number: CN201780089586.5A
Authority: CN
Inventors: 何强
Original assignee: Guangzhou Improve Medical Technology Co ltd
Current assignee: Yangpu Medical Technology Co ltd
Priority date: 2017-04-12
Filing date: 2017-04-12
Publication date: 2020-04-10
Anticipated expiration: 2037-04-12
Also published as: CN110998316B; WO2018187958A1

Abstract

A sensing cup, comprising: a sensing body (1) and a cup body (2). The cup body (2) is provided with an opening; the sensing body (1) comprises a cup cover (12), a cylinder sensing area (14) is arranged on one side of the cup cover (12), and when the cup cover (12) is covered with the opening, the cylinder sensing area (14) is arranged in the cup body (2); the other side of the cup cover (12) is provided with a taper hole (11), and the half angle of the taper top of the taper hole (11) is smaller than the static friction taper angle. Because the design of the taper hole (11) of the sensing body (1) for inserting the rotating rod conforms to the static friction taper principle, the sensing body (1) can be prevented from slipping off in the testing and assembling processes, and a good working state can be kept in the testing process, so that the testing result is stable and accurate.

Description

Sensing cup

Technical Field

The invention relates to the field of blood detection, in particular to a sensing cup.

Background

At present, the thromboelastogram instrument is an important tool for clinical blood coagulation full-face detection, and in actual clinic, the unstable and inaccurate test result caused by the structural design defect of the sample sensing cup seriously influences the correct and accurate diagnosis of a doctor on a patient, and is extremely unfavorable for diagnosis and treatment of the patient.

Refer to patent CN201420787158, this patent provides a sample cup subassembly, the sample cup subassembly includes cup and bowl cover, the cup is for having one end open-ended container, the bowl cover with the opening lid of cup closes, the bowl cover is equipped with stirring vane towards the surface of cup, stirring vane hold in the cup, the bowl cover be equipped with dwang complex through-hole, so that the dwang inserts the through-hole drives the bowl cover and rotates.

The defects of the sample cup assembly are as follows:

(1) the sample cup component is made of polypropylene materials, the materials are hydrophobic materials, contact angles are large, the materials are self-thinned to blood, fibrin in the blood is difficult to attach to the inner walls of the sensing body component and the cup body, and a 'cup sliding' phenomenon can occur in a testing process, namely blood clots are separated from the stirring wing and the inner surface of the cup body in a blood coagulation full-scale detection process, so that inaccurate testing results and testing failure are caused; (2) the through hole of the cup cover matched with the rotating rod has design defects, and the cup cover is separated from the rotating rod frequently in the actual blood coagulation detection process due to the fact that the hole of the cup cover matched with the rotating rod is the through hole, so that the experiment fails; (3) the structural design defect of bowl cover, bowl cover are equipped with the stirring wing piece towards the surface of cup, lacerate the blood clot easily in the blood coagulation testing process, and the stirring wing piece is thinner again because the material characteristic is soft simultaneously, and is undulant great in the blood coagulation testing process, and is very unstable, influences the detection of blood coagulation global appearance, leads to the inaccurate test result or even test failure.

Disclosure of Invention

The invention provides a sensing cup which can keep a good working state in a testing process, so that a testing result is stable and accurate.

The technical scheme of the sensing cup comprises the following steps:

a sensing body and a cup body;

the cup body is provided with an opening;

the sensing body comprises a cup cover, a cylinder sensing area is arranged on one side of the cup cover, and when the cup cover is covered with the opening, the cylinder sensing area is arranged in the cup body; the other side of the cup cover is provided with a taper hole, and the half angle of the taper top of the taper hole is smaller than the static friction taper angle.

Preferably, the first and second liquid crystal materials are,

the inner surface of the cup body consists of a closed surface vertical to the opening and a bottom surface connected with the closed surface; the cylinder sensing region, the closing surface and the bottom surface are frosted and coated with a reagent layer.

Preferably, the first and second liquid crystal materials are,

the bottom surface is an arc concave surface.

Preferably, the first and second liquid crystal materials are,

the frosting depth of the cylinder sensing area and the closed surface is 0.01016-0.1143 mm, and the minimum demoulding angle is 1-6.5 degrees.

Preferably, the first and second liquid crystal materials are,

the frosting depth of the bottom surface is 0.0254-0.1524 mm, and the minimum demoulding angle is 1.5-9 degrees.

Preferably, the first and second liquid crystal materials are,

the cylinder sensing area is solid, the bottom end surface is an arc convex surface, and the diameter of a sphere where the arc convex surface is located is smaller than that of a sphere where the arc concave surface is located.

Preferably, the first and second liquid crystal materials are,

the sensing body is further provided with a limiting step, the limiting step is located between the cup cover and the cylinder sensing area, and when the sensing body is covered with the opening, a gap is formed between the limiting step and the closed surface.

Preferably, the first and second liquid crystal materials are,

the sensing cup material is a transparent acrylonitrile-butadiene-styrene copolymer.

Preferably, the first and second liquid crystal materials are,

the cup body is provided with a handle.

The beneficial effect of adopting above-mentioned technical scheme is:

the sensing cup comprises a sensing body and a cup body, wherein the cup body is provided with an opening, the sensing body comprises a cup cover, one side of the cup cover is provided with a cylinder sensing area, and when the cup cover is covered with the opening, the cylinder sensing area is arranged in the cup body; the other side of the cup cover is provided with a taper hole, and the half angle of the taper top of the taper hole is smaller than the static friction taper angle. Because the design of the taper hole of the sensing body for inserting the sensing body of the rotating rod conforms to the static friction taper principle, the sensing body can be prevented from slipping off in the testing and assembling processes, and a good working state can be kept in the testing process, so that the testing result is stable and accurate.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.

FIG. 1 is an exploded view of a sensing cup according to an embodiment of the present invention;

FIGS. 2(a) and (b) are a structural view and a sectional view of a sensing body in a sensing cup according to an embodiment of the present invention;

FIGS. 3(a), (b) are top and structural views of a cup in a sensing cup according to an embodiment of the present invention;

FIGS. 4(a) and (b) are a force diagram and a force parallelogram rule of the sensing body in the sensing cup according to the embodiment of the present invention;

FIGS. 5(a) and (b) are a force-bearing schematic diagram and a mechanical schematic diagram of a taper hole friction cone of the sensing cup according to the embodiment of the present invention in a static state;

FIG. 6 is a graphical representation of the elastic deformation factor K versus the relative bearing ratio parameter ξ;

FIG. 7 is a schematic diagram of a tumbler design principle analysis of a sensor body;

FIG. 8 is a cross-sectional view and a static force diagram of a sensing cup according to an embodiment of the present invention.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

As shown in fig. 1, the sensing cup of the present invention includes a sensing body 1 and a cup body 2.

Referring to fig. 1 and 3(a) and (b), the cup body 2 includes a handle 21 and a cup body 22, and the cup body 22 is a container with one end open.

As shown in fig. 1 and fig. 2(a) and (b), the sensing body 1 includes a lid 12, a cylinder sensing area 14 is provided on one side of the lid 12, and when the lid 12 is covered with the opening, the cylinder sensing area 14 is embedded in the cup 2; the other side of the cup cover 12 is provided with a taper hole 11, and the half angle of the taper top of the taper hole 11 is smaller than the static friction taper angle, so that the rotating rod is inserted into the taper hole 11 to drive the sensing body 1 to rotate, and the blood coagulation condition of the blood sample in the cup body 22 can be sensed and detected through the cylinder sensing area 14 on the sensing body 1. It should be noted that the rotating rod is disposed on the rotating unit, which belongs to the prior art and is not described herein. Further, as shown in fig. 2b, the cross-sectional area of the tapered hole 11 is gradually reduced along a direction approaching the cup lid 12, and the bottom surface of the tapered hole 11 may extend to the cylinder sensing area 14.

Because the half angle of the cone top of the cone hole 11 of the sensing body 1 is smaller than the static friction angle, namely the design of the cone hole 11 of the sensing body 1 for inserting the rotating rod meets the static friction cone principle, the sliding of the sensing body 1 in the testing and assembling process can be avoided.

As will be described below with reference to fig. 4(a) and (b), the sensor 1 is first simplified to a circular point, and a friction factor is introduced, where the friction factor is a ratio of a normal load to a tangential friction, that is, μ ═ F_Nwhere/F μ is tan ρ (FN is the reaction force applied by the rotating lever), the derived friction angle ρ is arctan μ. According to the force parallelogram rule, the tangential friction force F mu and the normal load F can be obtained_NThe resultant force of (F) is FR, and the angle ρ between FR and F μ is called the rubbing angle.

In order to enable the taper hole 11 to have certain clamping force on the rotating rod, the surface roughness of the taper hole 11 reaches more than 0.05mm, according to the modern theory of solid friction, the friction force is composed of a molecular component and a mechanical deformation component, when the surface roughness value Ra is more than 50 micrometers, the molecular component can be ignored, and therefore according to the modern friction theory, the mechanical deformation component is the main friction force.

The friction factor μ is calculated as:

wherein:

the tensile hysteresis loss factor α is 0.08-0.12, r is the peak radius of the microscopic profile and is 0.01016-0.1 mm, h is the depth of the pressed surface under the action of the interaction force and is 0.01-0.0287 mm, and as shown in FIG. 6, K is a factor according to the relative support ratio curve parameter ξ during elastic deformation, and the relative support ratio curve parameter ξ is 1.8-3.

As shown in fig. 5(a) and (b), when the sensor body 1 is engaged with the rotating lever, the tangential force along the contact surface changes, and the formula ρ ═ arctan μ is always satisfied, regardless of whether the sensor body 1 is at rest, during testing, or when the sensor body 1 is loaded or unloaded. The mechanical analysis is carried out on the sensing body 1, the friction force received by the sensing body 1 is the largest when the sensing body 1 is unloaded but not separated from the rotating disc rotating rod, the received gravity G and the external force f are in the same direction, namely the critical friction force

At this time

The resultant force of the pressure FNf of the rotating rod of the turntable on the conical surface of the sensing body 1 forms a static friction cone with 2 theta as the conical angle. When F mu and F_NThe resultant force is located in the static friction cone, and the object cannot slide, namely, the friction angle rho is smaller than a certain critical angle (the critical angle is the static friction angle), and the object cannot slide.

Through the above explanation, it can be understood that taper hole 11 in sensing body 1 accords with the stiction awl principle, can not appear sliding phenomenon, has solved the problem that the blood coagulation detection in-process appears sensing body 1 and breaks away from the carousel dwang and leads to the experiment failure.

As shown in fig. 7, the structure of the sensing body 1 has a "tumbler" mechanical principle. The "upper end" of the sensor 1 is the end surface with the taper hole 11, and the "lower end" is the direction of the sensor 1 toward the inner surface of the cup bottom (hereinafter, both ends of the sensor 1 will be described as "upper end" and "lower end"). The upper end of the sensing body 1 is provided with a taper hole 11, and the sensing body is a hollow body with light weight; the lower end is a column and solid hemisphere, the weight is larger, and the gravity center of the sensing body 1 is in the hemisphere. It will be appreciated that the area of cylinder sensing zone 14 excluding the tapered bore 11 is of solid construction.

When the sensing body 1 is placed in a cup body 2 in a stationary state, the sensing body 1 is stressed by gravity G and a supporting force FN. of the cup body 2 to the sensing body 2 is inclined, when the sensing body 1 is placed in an inclined state, the cylinder sensing area bottom surface 131 is in contact with the cup body bottom surface 222, the gravity center of the sensing body 1 is O, the contact point is C, the gravity is G, the sensing body 1 is inclined by an angle α, the sensing body 1 is subjected to a force F which keeps an inclined state, the distance from the point F to the point C is M, AO, and OC are i and d respectively, when the sensing body 1 is inclined, an external force F is applied, an interference torque M1 is generated, the interference torque M1 is F M, the gravity G forms a centering torque M2, the centering torque M2 is Gcos β d, the two torques are opposite, the offset of the gravity line G is increased as the angle α of the sensing body 1 is increased continuously along with the inclination, the centering torque M2 is increased, the offset of the gravity line G is increased, the centering torque M2, the centering torque M β is increased, the centering torque M14 is increased, the centering torque M23 is increased, the centering torque M14 is increased when the sensing body 1 is not subjected to a center of a sensing area where the sensing body, the sensing area where the center of a sensing body is increased, the center of a sensing area where the center of a sensing body is not increased, the center of a sensing body is a sensing area where the center of a sensing area, the center of a sensing area of a.

As described above, the tumbler mechanics principle design method of the sensing body 1 can avoid inaccurate results caused by the fact that the sensing body 1 cannot be accurately placed at the central position in the cup body 22 in actual operation, thereby ensuring the loading precision and the detection precision of the sensing body 1.

The sensing cup of the present invention has the following contents, in addition to the above-mentioned half angle of the vertex of the tapered hole 11 being smaller than the static friction angle:

the cup cover 12 of the sensing body 1 is covered with the opening of the cup body 22, the cup cover 12 can be a cylinder cover with the thickness of 1mm and is used for covering the opening, a limiting step 13 is further arranged between the cup cover 12 and the cylinder sensing area 14, and the limiting step 13 is the cup cover 12 with the thickness of 0.8mm and the diameter smaller than that of the cylinder and is accommodated in the cup body 22. From the above description, it is clear that there is an assembly gap s between the outer edge of the limit step 13 and the inner surface of the cup body 22, where s is 0.1-0.5 mm, so as to limit the position of the sensor 1.

The inner surface of the sensing body 1 facing the cup body 22 is provided with a cylinder sensing region 14 for sensing and measuring blood coagulation, and the cylinder sensing region 14 is accommodated in the cup body 22. Cylinder sensing zone 14 includes a cylinder sensing zone side 132 and a cylinder sensing zone bottom 131, where cylinder sensing zone bottom 131 may be designed as a convex circular arc surface that mates with cup bottom 222, cup bottom 222 may be a concave circular arc surface, and the diameter of the sphere on which cylinder sensing zone bottom 131 is located is much smaller than the diameter of the sphere on which cup bottom 222 is located. As shown in fig. 2, the sensing region 14 of the sensor 1 is designed to be a cylindrical structure, so that the change of blood coagulation can be sensed uniformly during the blood coagulation test, the instability of the blood coagulation process is reduced to the maximum extent, and the problem of instability of the sensor with a fin structure during the blood coagulation detection process is solved.

The internal surface of cup body 22 by the perpendicular to open-ended closing surface 221 with the cup body bottom surface 222 that closing surface 221 is connected constitutes, cup body bottom surface 222 design is the circular arc concave surface, and the central point that slides into more easily under the effect of gravity when the sensing body 1 inclines is convenient for, avoids sensing body 1 in actual operation to lead to the carousel dwang to be difficult to insert taper hole 11 or insert the increase of taper hole 11 error because the skew center is too big to the inaccurate and unstable problem of test result that leads to.

The inner surfaces of the cylindrical sensing region 14 and the cup body 22 of the sensor body 1 are both frosted and coated with a reagent layer for increased surface area and sensitivity. The frosting depth of the side surface 132 of the cylinder sensing area, the bottom surface 131 of the cylinder sensing area and the closing surface 221 vertical to the opening is 0.01016-0.1143 mm, the minimum demoulding angle is 1-6.5 degrees, the frosting depth of the bottom surface 222 of the cup body with the arc concave surface is 0.0254-0.1524 mm, and the minimum demoulding angle is 1.5-9 degrees, so that the blood contact area is increased, and fibrin in blood can be better attached to the surface. The reagent layer is matched with a blood coagulation mechanism, so that the problems of inaccurate test result and test failure caused by separation of blood clots from the surface of the cylinder sensing area 14 in the blood coagulation full-face detection process are solved, the sensitivity of blood coagulation sensing process and measurement is increased, and the accuracy of the test is improved.

The sensing cup assembly provided by the invention is made of transparent acrylonitrile-butadiene-styrene copolymer, and specifically can be MABS PA-758(MABS chemical name is methyl methacrylate-acrylonitrile-butadiene-styrene plastic, PA-758 is model) or acrylic-based resin. The material is a hydrophilic material, the contact angle is 65-85 degrees, fibrin in blood can be better attached to the surface, and the sensitivity of sensing the blood coagulation process and measuring is increased. The problems of inaccurate results and test failure caused by the phenomenon of 'cup sliding' caused by the separation of blood clots from the surface of the sensing body and the inner surface of the cup body in the blood coagulation detection process are solved.

The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims

A sensing cup, comprising: a sensing body and a cup body;

the cup body is provided with an opening;

the sensing body comprises a cup cover, a cylinder sensing area is arranged on one side of the cup cover, and when the cup cover is covered with the opening, the cylinder sensing area is arranged in the cup body; the other side of the cup cover is provided with a taper hole, and the half angle of the taper top of the taper hole is smaller than the static friction taper angle.

The sensing cup of claim 1, wherein the cup body inner surface is comprised of a closed side perpendicular to the opening and a bottom side connected to the closed side; the cylinder sensing region, the closing surface and the bottom surface are frosted and coated with a reagent layer.

The sensing cup of claim 2, wherein the bottom surface is concave with a radius.
The sensing cup of claim 2, wherein the cylinder sensing area and the closing surface are frosted to a depth of 0.01016-0.1143 mm and a minimum de-molding angle of 1-6.5 °.
The sensing cup of claim 2, wherein the bottom surface has a frosted depth of 0.0254 to 0.1524mm and a minimum release angle of 1.5 ° to 9 °.
The sensing cup of claim 3, wherein the cylindrical sensing area is solid and has a bottom surface with a convex circular arc surface, and the convex circular arc surface is located on a sphere with a smaller diameter than the concave circular arc surface.
The sensing cup of claim 2, wherein the sensing body is further provided with a limiting step, the limiting step is located between the cup cover and the cylinder sensing area, and when the sensing body is covered with the opening, a gap is formed between the limiting step and the closing surface.
The sensing cup of claim 1, wherein the sensing cup material is a transparent acrylonitrile-butadiene-styrene copolymer.
The sensing cup of claim 8, wherein the transparent acrylonitrile-butadiene-styrene copolymer model is MABS PA-758 or an acrylic-based resin.
The sensing cup of claim 1, wherein a handle is provided on the cup body.