CN110960640A - Traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion and preparation method thereof - Google Patents

Traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion and preparation method thereof Download PDF

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CN110960640A
CN110960640A CN201911313185.0A CN201911313185A CN110960640A CN 110960640 A CN110960640 A CN 110960640A CN 201911313185 A CN201911313185 A CN 201911313185A CN 110960640 A CN110960640 A CN 110960640A
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traditional chinese
chinese medicine
digestive system
system diseases
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王一鸣
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Qinan Mingshengtang Acupuncture Hospital
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Qinan Mingshengtang Acupuncture Hospital
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Abstract

The invention relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion and a preparation method thereof; the composition is prepared from the following raw materials in parts by weight: 18-25 parts of immature bitter orange, 6-9 parts of honey-fried licorice root, 4-7 parts of medicated leaven, 7-10 parts of costustoot, 5-8 parts of poria cocos, 3-5 parts of mangnolia officinalis, 10-15 parts of rhizoma alismatis, 8-12 parts of katsumade galangal seed, 4-6 parts of liquorice, 8-15 parts of radix glehniae, 6-10 parts of fructus toosendan, 11-16 parts of pericarpium citri reticulatae viride, 3-6 parts of pinellia ternata and a proper amount of honey; the invention takes the extracts of immature bitter orange, medicated leaven and radix glehniae as the raw materials for preparing the traditional Chinese medicine prescription, wherein the effective components in the extracts of the immature bitter orange, the medicated leaven and the radix glehniae cooperate with each other to play the roles of nourishing yin and stomach, regulating middle warmer and promoting qi circulation and removing food retention; in addition, the traditional Chinese medicine prescription prepared by the invention can be used in combination with acupuncture techniques, and can remarkably improve the effect and efficacy of treating digestive system diseases.

Description

Traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion and a preparation method thereof.
Background
The digestive system consists of two major parts, the digestive tract and the digestive glands. The digestive tract: including the mouth, pharynx, esophagus, stomach, small intestine (duodenum, jejunum, ileum) and large intestine (cecum, appendix, colon, rectum, anal canal). Clinically, the part from the mouth to the duodenum is called the upper digestive tract, and the part below the jejunum is called the lower digestive tract. The digestive glands include small digestive glands and large digestive glands. The small digestive gland powder is located in the wall of each part of the digestive tract, and the large digestive gland has three pairs of salivary glands (parotid gland, submandibular gland and sublingual gland), liver and pancreas. The digestive system is one of the nine major systems of the human body. The importance of the digestive system to the human body is self evident. But suffers from digestive system diseases due to the carelessness of people in ordinary diet or ordinary bad living habits.
At present, when digestive system diseases are treated, people mostly take some western medicines to achieve the purpose of relieving or treating diseases. Although the method takes effect quickly, the method has large toxic and side effects on human bodies. Therefore, people usually take traditional Chinese medicines to relieve or treat the symptoms in order to reduce the harm to the body, but the traditional Chinese medicines have relatively long effective time. Acupuncture and moxibustion is an important component of Chinese medicine, and has the advantages of wide application, obvious curative effect, convenient operation, economy, safety and the like. Therefore, combining the advantages and disadvantages of acupuncture and moxibustion and traditional Chinese medicine, providing a method for treating digestive system diseases by combining traditional Chinese medicine and acupuncture and moxibustion becomes a technical problem to be solved by those skilled in the art.
Disclosure of Invention
In view of the above problems, the present invention provides a Chinese medicinal formulation for treating digestive system diseases in combination with acupuncture and a preparation method thereof, which are used for solving the technical problems in the background art.
In order to achieve the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion comprises the following raw materials in parts by weight: 18-25 parts of immature bitter orange, 6-9 parts of honey-fried licorice root, 4-7 parts of medicated leaven, 7-10 parts of costustoot, 5-8 parts of poria cocos, 3-5 parts of mangnolia officinalis, 10-15 parts of rhizoma alismatis, 8-12 parts of katsumade galangal seed, 4-6 parts of liquorice, 8-15 parts of radix glehniae, 6-10 parts of fructus toosendan, 11-16 parts of pericarpium citri reticulatae viride, 3-6 parts of pinellia ternata and a proper amount of honey.
A preparation method of a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture comprises the following steps:
s1, cleaning the traditional Chinese medicines with clear water, then respectively placing the traditional Chinese medicines into a constant-temperature drying box for drying treatment, and then sequentially placing the dried immature bitter orange, medicated leaven and radix glehniae into a grinder and a grinder for grinding, grinding and sieving treatment; storing the finally obtained immature bitter orange, medicated leaven and radix glehniae fine powder for later use;
s2, respectively putting the dried traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae in the S1 into a pulverizer for pulverization, respectively sieving the pulverized traditional Chinese medicines with a 100-200-mesh sieve, transferring the obtained raw material powder into an extractor, and adding a proper amount of extracting solution into the extractor for heating reflux extraction for 2-3 times; wherein, the extraction time is 30-40min each time, filtering, mixing the Chinese medicinal extractive solutions, and storing the Chinese medicinal extractive mixed solution;
s3, adding a proper amount of deionized water into the Chinese medicine extraction mixed liquor obtained in the step S2, and concentrating under reduced pressure until the relative density of the Chinese medicine extraction mixed liquor is 1.18-1.26 to obtain an extract; then subjecting the obtained extract to column elution, discarding water washing solution, performing elution treatment with ethanol solution, collecting ethanol elution part and recovering ethanol, and performing reduced pressure concentration and drying treatment to obtain extract powder;
and S4, refining honey by using honey, mixing the extract powder obtained in the step S3 with the refined honey and the fine powder of the immature bitter orange, the medicated leaven and the radix glehniae obtained in the step S1, uniformly stirring, and then putting the obtained mixture into an automatic traditional Chinese medicine pill making machine for making pills, wherein the obtained pills are finished products of the traditional Chinese medicine formula.
Furthermore, the temperature of the constant temperature drying oven in the step S1 is set to be 75-85 ℃, and the ground immature bitter orange, medicated leaven and radix glehniae are respectively sieved by a 200-300-mesh sieve.
Furthermore, the extracting solution in the step S2 is ethanol solution with concentration of 50-70%, and the dosage of the ethanol solution is 7-11 times of the total mass of the traditional Chinese medicines except for the immature bitter orange, the medicated leaven and the radix glehniae.
Further, the temperature of the concentration under reduced pressure in the step S3 is 70-80 ℃.
Furthermore, in the elution process in the step S3, the macroporous adsorption resin is selected from AB-8 or HPD400, and the amount of deionized water used in the elution is 4-6 times of the column volume.
Furthermore, the amount of the honey in the S4 accounts for 35-45% of the total mass of the traditional Chinese medicine powder.
Further, the mixing and stirring speed in the S4 is 200-400 r/min.
Further, each of the pills prepared in S4 weighs 8-10 g.
By adopting the technical scheme, the invention has the beneficial effects that:
the invention takes the extracts of immature bitter orange, medicated leaven and radix glehniae as the raw materials for preparing the traditional Chinese medicine prescription, wherein the effective components in the extracts of the immature bitter orange, the medicated leaven and the radix glehniae cooperate with each other to play the roles of nourishing yin and stomach, regulating middle warmer and promoting qi circulation and removing food retention. And the effective components in the three can be matched with each other to effectively treat symptoms such as inappetence, dull stomach pain, gastral cavity fullness and the like. Thereby playing a certain role in treating digestive system diseases. Furthermore, the mutual compatibility of the effective traditional Chinese medicine components in honey-fried licorice root, costustoot, tuckahoe, magnolia officinalis, alisma orientale, katsumade galangal seed, liquorice, fructus toosendan, green tangerine orange peel and pinellia ternata can also achieve the purpose of treating the symptoms of gastric cavity fullness, heartburn in stomach, abdominal pain and the like. The Chinese medicinal components in the Chinese medicinal preparation are matched with each other to have good treatment effect on digestive system diseases. After the patient takes the traditional Chinese medicine prescription prepared by the invention, the effect and the efficacy of treating digestive system diseases can be obviously improved by using acupuncture and moxibustion techniques. Moreover, the use of acupuncture is easier to operate, no needle is left, the acupuncture pain is less, the anti-inflammation range is wide, the effect is quick, and the curative effect is high and better. And the wound area is smaller, the risk is less, and simultaneously, the method is safer and more reliable. Thereby accelerating the cure of digestive system diseases of patients and reducing the suffering of the patients.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without any inventive step, are within the scope of the present invention.
Example 1:
a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion comprises the following raw materials in parts by weight: 20 parts of immature bitter orange, 6 parts of honey-fried licorice root, 5 parts of medicated leaven, 7 parts of costustoot, 6 parts of poria cocos, 3 parts of magnolia officinalis, 12 parts of rhizoma alismatis, 8 parts of katsumade galangal seed, 5 parts of liquorice, 8 parts of radix glehniae, 7 parts of fructus toosendan, 11 parts of green tangerine peel, 4 parts of pinellia ternata and a proper amount of honey.
A preparation method of a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture comprises the following steps:
s1, cleaning the traditional Chinese medicines with clear water, then respectively placing the traditional Chinese medicines into a constant-temperature drying box for drying treatment, and then sequentially placing the dried immature bitter orange, medicated leaven and radix glehniae into a grinder and a grinder for grinding, grinding and sieving treatment; storing the finally obtained immature bitter orange, medicated leaven and radix glehniae fine powder for later use;
s2, respectively putting the dried traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae in the S1 into a grinder for grinding, respectively sieving through a 100-mesh sieve, transferring the obtained raw material powder into an extractor, and adding a proper amount of extracting solution into the extractor for heating reflux extraction for 2 times; wherein, the extraction time is 30min each time, the traditional Chinese medicine extracting solution obtained each time is combined after filtration treatment, and the obtained traditional Chinese medicine extracting mixed solution is stored for standby;
s3, adding a proper amount of deionized water into the Chinese medicine extraction mixed liquor obtained in the step S2, and concentrating under reduced pressure until the relative density of the Chinese medicine extraction mixed liquor is 1.18 to obtain an extract; then subjecting the obtained extract to column elution, discarding water washing solution, performing elution treatment with ethanol solution, collecting ethanol elution part and recovering ethanol, and performing reduced pressure concentration and drying treatment to obtain extract powder;
and S4, refining honey by using honey, mixing the extract powder obtained in the step S3 with the refined honey and the fine powder of the immature bitter orange, the medicated leaven and the radix glehniae obtained in the step S1, uniformly stirring, and then putting the obtained mixture into an automatic traditional Chinese medicine pill making machine for making pills, wherein the obtained pills are finished products of the traditional Chinese medicine formula.
And S1, setting the temperature of the constant-temperature drying oven at 75 ℃, and respectively sieving the ground immature bitter orange, medicated leaven and radix glehniae with a 200-mesh sieve.
In the step S2, the extracting solution is ethanol solution with the concentration of 50%, and the dosage of the ethanol solution is 7 times of the total mass of the traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae.
The temperature at which concentration was carried out under reduced pressure in step S3 was 70 ℃.
In the elution process in the step S3, the macroporous adsorption resin is AB-8, and the dosage of the deionized water is 4 times of the column volume during the elution.
The amount of honey in the S4 accounts for 35% of the total mass of the traditional Chinese medicine powder.
The mixing and stirring speed in S4 is 200 r/min.
Each pill made in S4 weighed 8 g.
The method for treating gastrointestinal excess heat and constipation comprises the following steps:
100 patients suffering from excessive gastrointestinal heat or constipation were randomly selected and allowed to take the Chinese medicinal formulation prepared in example 1 one tablet at a time before acupuncture. Then, the doctor applies the needle to the three points of Dachangshu, Tianshu and Zusanli. The method is used for treating patients for half a month, and the patients are revisited after half a month, so that 94 patients are known to have completely disappeared, and the cure rate is as high as 94%.
Example 2:
a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion comprises the following raw materials in parts by weight: 18 parts of immature bitter orange, 7 parts of honey-fried licorice root, 4 parts of medicated leaven, 8 parts of costustoot, 5 parts of poria cocos, 3.5 parts of mangnolia officinalis, 10 parts of rhizoma alismatis, 9 parts of katsumade galangal seed, 4 parts of liquorice, 10 parts of radix glehniae, 6 parts of fructus toosendan, 13 parts of pericarpium citri reticulatae viride, 3 parts of pinellia ternata and a proper amount of honey.
A preparation method of a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture comprises the following steps:
s1, cleaning the traditional Chinese medicines with clear water, then respectively placing the traditional Chinese medicines into a constant-temperature drying box for drying treatment, and then sequentially placing the dried immature bitter orange, medicated leaven and radix glehniae into a grinder and a grinder for grinding, grinding and sieving treatment; storing the finally obtained immature bitter orange, medicated leaven and radix glehniae fine powder for later use;
s2, respectively putting the dried traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae in the S1 into a grinder for grinding, respectively sieving through a 150-mesh sieve, transferring the obtained raw material powder into an extractor, and adding a proper amount of extracting solution into the extractor for heating reflux extraction for 2 times; wherein, the extraction time is 35min each time, the traditional Chinese medicine extracting solution obtained each time is combined after filtration treatment, and the obtained traditional Chinese medicine extracting mixed solution is stored for standby;
s3, adding a proper amount of deionized water into the Chinese medicine extraction mixed liquor obtained in the step S2, and concentrating under reduced pressure until the relative density of the Chinese medicine extraction mixed liquor is 1.20 to obtain an extract; then subjecting the obtained extract to column elution, discarding water washing solution, performing elution treatment with ethanol solution, collecting ethanol elution part and recovering ethanol, and performing reduced pressure concentration and drying treatment to obtain extract powder;
and S4, refining honey by using honey, mixing the extract powder obtained in the step S3 with the refined honey and the fine powder of the immature bitter orange, the medicated leaven and the radix glehniae obtained in the step S1, uniformly stirring, and then putting the obtained mixture into an automatic traditional Chinese medicine pill making machine for making pills, wherein the obtained pills are finished products of the traditional Chinese medicine formula.
And S1, setting the temperature of the constant-temperature drying oven at 80 ℃, and respectively sieving the ground immature bitter orange, medicated leaven and radix glehniae with a 250-mesh sieve.
In the step S2, the extracting solution is ethanol solution with the concentration of 55%, and the dosage of the ethanol solution is 8 times of the total mass of the traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae.
The temperature at which concentration was carried out under reduced pressure in step S3 was 75 ℃.
In the elution process in the step S3, HPD400 is selected as the macroporous adsorbent resin, and the amount of deionized water used in the elution is 5 times the column volume.
The dosage of the honey in the S4 is 40 percent of the total mass of the traditional Chinese medicine powder.
The mixing and stirring speed in S4 is 240 r/min.
Each pill made in S4 weighed 9 g.
The method for treating yin deficiency constipation and habitual constipation comprises the following steps:
100 patients suffering from constipation due to yin deficiency or habitual constipation were randomly selected and allowed to take the Chinese medicinal prescription prepared in example 2 one tablet at a time before acupuncture. Then, the doctor performs acupuncture on the points of Tianshu, Zhigou, Shanghai Juxu, Sanyinjiao and Zhai. The method is used for treating the patients for half a month, and the patients are revisited after half a month, so that the 92 patients are known to have completely disappeared, and the cure rate is as high as 92%.
Example 3:
a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion comprises the following raw materials in parts by weight: 25 parts of immature bitter orange, 8 parts of honey-fried licorice root, 7 parts of medicated leaven, 9 parts of costustoot, 8 parts of poria cocos, 4 parts of mangnolia officinalis, 15 parts of rhizoma alismatis, 11 parts of katsumade galangal seed, 6 parts of liquorice, 12 parts of radix glehniae, 10 parts of fructus toosendan, 15 parts of green tangerine peel, 6 parts of pinellia ternata and a proper amount of honey.
A preparation method of a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture comprises the following steps:
s1, cleaning the traditional Chinese medicines with clear water, then respectively placing the traditional Chinese medicines into a constant-temperature drying box for drying treatment, and then sequentially placing the dried immature bitter orange, medicated leaven and radix glehniae into a grinder and a grinder for grinding, grinding and sieving treatment; storing the finally obtained immature bitter orange, medicated leaven and radix glehniae fine powder for later use;
s2, respectively putting the dried traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae in the S1 into a grinder for grinding, respectively sieving through a 170-mesh sieve, transferring the obtained raw material powder into an extractor, and adding a proper amount of extracting solution into the extractor for heating, refluxing and extracting for 3 times; wherein, the extraction time is 35min each time, the traditional Chinese medicine extracting solution obtained each time is combined after filtration treatment, and the obtained traditional Chinese medicine extracting mixed solution is stored for standby;
s3, adding a proper amount of deionized water into the Chinese medicine extraction mixed liquor obtained in the step S2, and concentrating under reduced pressure until the relative density of the Chinese medicine extraction mixed liquor is 1.25 to obtain an extract; then subjecting the obtained extract to column elution, discarding water washing solution, performing elution treatment with ethanol solution, collecting ethanol elution part and recovering ethanol, and performing reduced pressure concentration and drying treatment to obtain extract powder;
and S4, refining honey by using honey, mixing the extract powder obtained in the step S3 with the refined honey and the fine powder of the immature bitter orange, the medicated leaven and the radix glehniae obtained in the step S1, uniformly stirring, and then putting the obtained mixture into an automatic traditional Chinese medicine pill making machine for making pills, wherein the obtained pills are finished products of the traditional Chinese medicine formula.
And S1, setting the temperature of the constant-temperature drying box at 80 ℃, and respectively sieving the ground immature bitter orange, medicated leaven and radix glehniae through 280-mesh sieves.
In the step S2, the extracting solution is 65% ethanol solution, and the dosage of the ethanol solution is 10 times of the total mass of the traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae.
The temperature of the concentration under reduced pressure in step S3 was 70 to 80 ℃.
In the elution process in the step S3, the macroporous adsorption resin is AB-8, and the dosage of the deionized water is 5 times of the column volume during the elution.
The dosage of the honey in the S4 is 40 percent of the total mass of the traditional Chinese medicine powder.
The mixing and stirring speed in S4 is 300 r/min.
Each pill made in S4 weighed 9 g.
The method for treating deficiency-cold stomachache and dyspepsia comprises the following steps:
100 patients suffering from cold-deficiency stomachache or dyspepsia were randomly selected and allowed to take the Chinese medicinal prescription prepared in example 3 one tablet at a time before acupuncture. Then, the doctor applies the needle to the points of heaven, cowry-tongue, tongmen, Neiguan and Gong Sun. The method is used for treating patients for half a month, and the patients are revisited after half a month, so that 97 patients are known to have completely disappeared, and the cure rate is as high as 97%.
Example 4:
a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion comprises the following raw materials in parts by weight: 23 parts of immature bitter orange, 9 parts of honey-fried licorice root, 6 parts of medicated leaven, 10 parts of costustoot, 7 parts of poria cocos, 5 parts of magnolia officinalis, 14 parts of rhizoma alismatis, 12 parts of katsumade galangal seed, 5 parts of liquorice, 15 parts of radix glehniae, 8 parts of fructus toosendan, 16 parts of green tangerine peel, 5 parts of pinellia ternata and a proper amount of honey.
A preparation method of a traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture comprises the following steps:
s1, cleaning the traditional Chinese medicines with clear water, then respectively placing the traditional Chinese medicines into a constant-temperature drying box for drying treatment, and then sequentially placing the dried immature bitter orange, medicated leaven and radix glehniae into a grinder and a grinder for grinding, grinding and sieving treatment; storing the finally obtained immature bitter orange, medicated leaven and radix glehniae fine powder for later use;
s2, respectively putting the dried traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae in the S1 into a grinder for grinding, respectively sieving by a 200-mesh sieve, transferring the obtained raw material powder into an extractor, and adding a proper amount of extracting solution into the extractor for heating, refluxing and extracting for 3 times; wherein, the extraction time is 40min each time, filtering, mixing the Chinese medicinal extractive solutions, and storing the Chinese medicinal extractive mixed solution;
s3, adding a proper amount of deionized water into the Chinese medicine extraction mixed liquor obtained in the step S2, and concentrating under reduced pressure until the relative density of the Chinese medicine extraction mixed liquor is 1.26 to obtain an extract; then subjecting the obtained extract to column elution, discarding water washing solution, performing elution treatment with ethanol solution, collecting ethanol elution part and recovering ethanol, and performing reduced pressure concentration and drying treatment to obtain extract powder;
and S4, refining honey by using honey, mixing the extract powder obtained in the step S3 with the refined honey and the fine powder of the immature bitter orange, the medicated leaven and the radix glehniae obtained in the step S1, uniformly stirring, and then putting the obtained mixture into an automatic traditional Chinese medicine pill making machine for making pills, wherein the obtained pills are finished products of the traditional Chinese medicine formula.
And S1, setting the temperature of the constant-temperature drying oven at 85 ℃, and respectively sieving the ground immature bitter orange, medicated leaven and radix glehniae with a 300-mesh sieve.
In the step S2, the extracting solution is 70% ethanol solution, and the dosage of the ethanol solution is 11 times of the total mass of the traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae.
The temperature at which concentration was carried out under reduced pressure in step S3 was 80 ℃.
In the elution process in the step S3, HPD400 is selected as the macroporous adsorbent resin, and the amount of deionized water used in the elution is 6 times the column volume.
The amount of honey in the S4 accounts for 45% of the total mass of the traditional Chinese medicine powder.
The mixing and stirring speed in S4 is 400 r/min.
Each of the pills prepared in S4 weighed 10 g.
The method for treating infantile indigestion, vomiting of milk and indigestion comprises the following steps:
100 children with a disease of treatment of infantile dyspepsia, vomiting of milk or dyspepsia were randomly selected and given the Chinese medicinal formula prepared in example 4 one dose at a time before acupuncture. Then, the doctor performs acupuncture on the points of the upper abdomen, the middle abdomen, the Tianshu and the four sutures respectively. The method is used for treating patients for half a month, and the patients are revisited after half a month, so that the condition of 95 patients is completely disappeared, and the cure rate is as high as 95%.
The treatment results of the above examples show that the traditional Chinese medicine prepared by the invention has good treatment effect on digestive system diseases by being used in combination with acupuncture. The traditional Chinese medicine formula prepared by the invention has wide market prospect and is more suitable for popularization.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims (9)

1. A traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion is characterized by comprising the following raw materials in parts by weight: 18-25 parts of immature bitter orange, 6-9 parts of honey-fried licorice root, 4-7 parts of medicated leaven, 7-10 parts of costustoot, 5-8 parts of poria cocos, 3-5 parts of mangnolia officinalis, 10-15 parts of rhizoma alismatis, 8-12 parts of katsumade galangal seed, 4-6 parts of liquorice, 8-15 parts of radix glehniae, 6-10 parts of fructus toosendan, 11-16 parts of pericarpium citri reticulatae viride, 3-6 parts of pinellia ternata and a proper amount of honey.
2. The method for preparing a Chinese medicinal formulation for treating digestive system diseases in combination with acupuncture and moxibustion as claimed in claim 1, comprising the steps of:
s1, cleaning the traditional Chinese medicines with clear water, then respectively placing the traditional Chinese medicines into a constant-temperature drying box for drying treatment, and then sequentially placing the dried immature bitter orange, medicated leaven and radix glehniae into a grinder and a grinder for grinding, grinding and sieving treatment; storing the finally obtained immature bitter orange, medicated leaven and radix glehniae fine powder for later use;
s2, respectively putting the dried traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae in the S1 into a pulverizer for pulverization, respectively sieving the pulverized traditional Chinese medicines with a 100-200-mesh sieve, transferring the obtained raw material powder into an extractor, and adding a proper amount of extracting solution into the extractor for heating reflux extraction for 2-3 times; wherein, the extraction time is 30-40min each time, filtering, mixing the Chinese medicinal extractive solutions, and storing the Chinese medicinal extractive mixed solution;
s3, adding a proper amount of deionized water into the Chinese medicine extraction mixed liquor obtained in the step S2, and concentrating under reduced pressure until the relative density of the Chinese medicine extraction mixed liquor is 1.18-1.26 to obtain an extract; then subjecting the obtained extract to column elution, discarding water washing solution, performing elution treatment with ethanol solution, collecting ethanol elution part and recovering ethanol, and performing reduced pressure concentration and drying treatment to obtain extract powder;
and S4, refining honey by using honey, mixing the extract powder obtained in the step S3 with the refined honey and the fine powder of the immature bitter orange, the medicated leaven and the radix glehniae obtained in the step S1, uniformly stirring, and then putting the obtained mixture into an automatic traditional Chinese medicine pill making machine for making pills, wherein the obtained pills are finished products of the traditional Chinese medicine formula.
3. The method for preparing a Chinese medicinal formulation for treating digestive system diseases in combination with acupuncture according to claim 2, wherein: the temperature of the constant-temperature drying box in the S1 is set to be 75-85 ℃, and the ground immature bitter orange, medicated leaven and radix glehniae are respectively sieved by a 200-5-mesh sieve.
4. The method for preparing a Chinese medicinal formulation for treating digestive system diseases in combination with acupuncture according to claim 2, wherein: in the step S2, the extracting solution is ethanol solution with concentration of 50-70%, and the dosage of the ethanol solution is 7-11 times of the total mass of the traditional Chinese medicines except the immature bitter orange, the medicated leaven and the radix glehniae.
5. The method for preparing a Chinese medicinal formulation for treating digestive system diseases in combination with acupuncture according to claim 2, wherein: the temperature of the concentration under reduced pressure in the step S3 is 70-80 ℃.
6. The method for preparing a Chinese medicinal formulation for treating digestive system diseases in combination with acupuncture according to claim 2, wherein: in the elution process in the step S3, the macroporous adsorption resin is AB-8 or HPD400, and the dosage of deionized water is 4-6 times of the column volume during elution.
7. The method for preparing a Chinese medicinal formulation for treating digestive system diseases in combination with acupuncture according to claim 2, wherein: the amount of honey in the S4 accounts for 35-45% of the total mass of the traditional Chinese medicine powder.
8. The method for preparing a Chinese medicinal formulation for treating digestive system diseases in combination with acupuncture according to claim 2, wherein: the mixing and stirring speed in the S4 is 200-400 r/min.
9. The method for preparing a Chinese medicinal formulation for treating digestive system diseases in combination with acupuncture according to claim 2, wherein: the weight of each pill prepared in S4 is 8-10 g.
CN201911313185.0A 2019-12-18 2019-12-18 Traditional Chinese medicine prescription for treating digestive system diseases by combining acupuncture and moxibustion and preparation method thereof Pending CN110960640A (en)

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