CN110292622A

CN110292622A - A kind of Chinese medicine composition and preparation method thereof for treating meningioma

Info

Publication number: CN110292622A
Application number: CN201910641828.8A
Authority: CN
Inventors: 陈海林; 陈凌峰
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-07-16
Filing date: 2019-07-16
Publication date: 2019-10-01
Also published as: CN117815349A

Abstract

The invention discloses a kind of Chinese medicine compositions for treating meningioma, by Radix Astragali, arisaema cum bile, the non-irrigated tuber of pinellia, seaweed, bulbus fritillariae cirrhosae, Rhizoma Chuanxiong, Ramulus euonymi, pheretima, dens draconis, Rhizoma Anemones Altaicae, scorpio, centipede, SHENLIUGU, Prunella vulgaris, sky dragon, asparagus fern, the root of straight ladybell, fructus viticis, fushen, cicada slough, Fructus Liquidambaris, magnetite, peach kernel, umbellate pore furgus, the larva of a silkworm with batrytis, Radix Notoginseng, fingered citron, radix pseudostellariae, Radix Curcumae, leech, tortoiseshell, thallus laminariae, Rhizoma Atractylodis Macrocephalae, turtle shell, Radix Glycyrrhizae composition, the present invention is with removing toxic substances of clearing liver, strengthening spleen, tonifying kidney, dampness removing resolving sputum, ascending the clear and descending the turbid is that theoretical basis carries out a group medicine, various bulk pharmaceutical chemicals are mutually coordinated can to play drug effect to the greatest extent together, effective treatment is because of speen-kidney dificiency, phlegm wet hinders network, lucid yang failing to raise, meningioma caused by failure in sending down turbid yin, therapeutic effect is obvious, it has no toxic side effect, cure rate is high, securely and reliably.

Description

A kind of Chinese medicine composition and preparation method thereof for treating meningioma

Technical field

The present invention relates to a kind of Chinese medicine compositions and preparation method thereof, and in particular to a kind of Chinese traditional medicine composition for treating meningioma Object and preparation method thereof belongs to field of medicaments.

Background technique

Meningioma is initiated by the derivative of meninx and spatium interdurale, and disease incidence accounts for the 19.2% of intracranial tumors, occupies the 2nd Position, women: the disease rates of male are 2:1, the onset peak age at 45 years old, children are rare but child patient recurrence rate compared with It is high.Many asymptomatic meningiomas are mostly to chance on.Multiple meningiomas is once in a while as it can be seen that there is the report of family history in document.50% Positioned at Parasagittal sinus, another convexity of brain, cerebral falx side person is common, secondly for sphenoid rige, tubercle of sellae, olfactory sulcus, cerebellopontile angle with The positions such as tentorium cerebelli, it is seldom to be grown in person in the ventricles of the brain, also seen in Epidural cavity.Other positions are accidental.

Occurring for meningioma may be related with the change of certain interior environment and genetic mutation, and not single factors cause, can Energy and craniocerebral trauma, the factors such as radio exposure, virus infection and merging Bilateral Acoustic Neroumas are related.Have been generally acknowledged that arachnoid The split speed of cell be it is very slow, appeal factor accelerates the split speed of cell, it may be possible to lead to the early stage of cell degeneration Important stage.

In addition to brain tumor coexpress, meningioma also has following features: 1. usual slow growth, the course of disease are long, generally 2-4 Year, minority growth is rapid, the course of disease is short, and postoperative easy to recur and change especially sees children；2. tumour grows huge, symptom is light Micro-, clinical manifestation is eyeground papilloedema, but it is inviolent to have a headache, and loses generation when nervous system and tastes, the state of an illness just occurs and dislike rapidly Change, this is with glioma on the contrary, the latter's growth rapidly, occurs going into a coma quickly or hernia cerebri, and eyeground can be normal.3. how first irritating Symptom, followed by paralysis symptom disclose tumour brain outgrowth.4. being found in any position of encephalic, but there is predilection site and corresponding comprehensive Close disease.

Current treatment method mainly has the drug therapy of operation excision, radiotherapy and auxiliary, operation excision meninx Tumor is relatively effective treatment means.With the development of micro-operative technique, the surgical effect of meningioma is continuously improved, and is made mostly Number patient is treated, but potential hazard is larger.

For radiotherapy while destroying tumour, normal tissue cell also will receive certain damage.Certain histocyte Tolerance to radioactivity line is that have certain limitation, will generate irreversible lesion more than this limitation dosage.Moreover, only pair Tumour less than 2cm could be destroyed disposably completely, can not destroy tumour cell completely to big tumour radiotherapy line.Radiation is controlled The dosage that cannot judge the effect and adjustment for the treatment of that cannot be instant for the treatment of immediately is treated, the dosage of radiation is come by theoretical calculation It completes, it is difficult to judge whether and actually be consistent, in addition radiotherapy is also possible to reduce the immunity of body, and radiotherapy is often made For a kind of adjuvant treatment or palliative treatment, it is used as a kind of essential therapeutic arsenals once in a while；

The therapeutic effect of above-mentioned treatment method is all undesirable, big to patient body wound, Yi Yinfa complication, medical expense It is expensive.

Chinese traditional treatment is that the universal acceptance level of current patient is relatively high and small to patient trauma, and medical expense is cheap to be controlled Treatment mode, therefore this field needs that a kind of can effectively to treat Chinese medicine composition of meningioma and preparation method thereof above-mentioned to solve Problem.

Summary of the invention

In view of this, the present invention provides a kind of Chinese medicine composition and preparation method thereof for treating meningioma, the present invention with The lesion of cholesteatoma recurrence after operation and meningioma is the interpretation of the cause, onset and process of an illness, carries out medicament composing prescription, determines that pharmacological property turns in this pathomechanism Time pharmacology played in change, evolution process and medicine promote oncocyte to switch to human normal physiological cells rapidly for power.

To achieve the goals above, the present invention adopts the following technical scheme:

The Chinese medicine composition for treating meningioma, is composed of the following raw materials by weight: 12-25 parts of Radix Astragali, arisaema cum bile 10-20 Part, non-irrigated 15-25 parts of the tuber of pinellia, 15-25 parts of seaweed, 15-25 parts of bulbus fritillariae cirrhosae, 15-25 parts of Rhizoma Chuanxiong, 15-25 parts of Ramulus euonymi, pheretima 15- 25 parts, 15-25 parts of dens draconis, 15-25 parts of Rhizoma Anemones Altaicae, 10-20 parts of scorpio, centipede 2-4 item, 15-25 parts of SHENLIUGU, Prunella vulgaris 15- 25 parts, 10-20 parts of sky dragon, 15-25 parts of asparagus fern, 15-25 parts of the root of straight ladybell, 10-20 parts of fructus viticis, 15-25 parts of fushen, cicada slough 10-20 Part, 15-25 parts of Fructus Liquidambaris, 20-40 parts of magnetite, 10-20 parts of peach kernel, 15-25 parts of umbellate pore furgus, 15-25 parts of the larva of a silkworm with batrytis, Radix Notoginseng 15- 25 parts, 15-25 parts of fingered citron, 15-25 parts of radix pseudostellariae, 15-25 parts of Radix Curcumae, 10-20 parts of leech, 20-40 parts of tortoiseshell, thallus laminariae 15-25 Part, 15-25 parts of Rhizoma Atractylodis Macrocephalae, 20-40 parts of turtle shell, 10-20 parts of Radix Glycyrrhizae.

It is reason that the present invention, which treats the Chinese medicine composition of meningioma with removing toxic substances of clearing liver, strengthening spleen, tonifying kidney, dampness removing resolving sputum, ascending the clear and descending the turbid, A group medicine is carried out by basis, various bulk pharmaceutical chemicals are mutually coordinated can to play drug effect to the greatest extent together, and effective treatment is because of spleen Kidney two is empty, phlegm wet hinders meningioma caused by network, lucid yang failing to raise, failure in sending down turbid yin, and therapeutic effect is obvious, has no toxic side effect, cure rate Height, securely and reliably.

Medicament composing prescription to the ill carries out gasification maincenter (taste) in gasification intervener's body, carries out the liter of gas exchanges (mechanism) Drop enters and leaves, and into lesion, contains the diffusion and transfer of cancer cell rapidly, the cancer cell for directly destroying mutation goes to repair deletion mutation Cell and cytoplasm, developed through multi-faceted gasification, it is safe in an orderly manner to reverse cancer cell rapidly as normal physiological cells.

So-called " gasification ", that is the various biological phenomenas in nature are on the basis of nature normal climate variation Upper generation, there is gas then having, gas is not just changed.Described in " Tianyuan, which is recorded, discusses greatly a piece ": " it is gas in day, is shape on ground, The sense of shape gas phase and metaplasia all things on earth ", therefore Huangdi's Internal Classics are also entirely from " gas for Human Physiology and physiopathologic understanding Change " angle recognize, study from the angle of " gasification " physiological phenomenon of human body, pathological phenomenon, disease diagnosis, control Treatment and Precautionary Principle, to be rapidly reached the purpose of radical cure tumour by the differentiation of gasification.

Specifically, the function of medicine for oral administration each component of the present invention is respectively:

Radix Astragali, sweet in flavor, slightly warm in nature, returns spleen, lung channel, invigorating qi for strengthening superficies, pus draining and toxin expelling, diuresis, myogenic, for deficiency of vital energy and acking in strength, Rush down prolapse of the anus for a long time, spontaneous perspiration, oedema, uterine prolapse, chronic rephrilis protinuria, diabetes, the long disunion of the open sore part.

Arisaema cum bile, fine powder and ox, sheep or the pig's bile of Rhizoma Arisaematis (processed) process from strand, or for unprocessed Arisaema erubescens fine powder and ox, Sheep or pig's bile is fermented is process.Bitter, micro-pungent, it is cool in nature.Return lung, liver, the spleen channel.Clearing heat and eliminating phlegm, dispelling wind and relieving convulsion.For phlegm Heat cough, cough up phlegm yellow thick, stroke and phlegm confusing heart, demented frightened epilepsy.

The non-irrigated tuber of pinellia, acrid flavour is warm-natured, toxic.Returns spleen, stomach, lung channel.With stopping nausea and vomiting by lowering the adverse flow of QI, mild middle stomach is eliminating dampness and eliminating phlegm, disappears The effect of ruffian dissipating bind.Cure mainly abundant expectoration cough and asthma, anemophlegmatic vertigo, phlegm retention anti-dazzle nervous, phlegm and headache, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus Disease.

Seaweed, it is bitter, salty, it is cold in nature, return liver, stomach, kidney channel, dissolving phlegm resolving hard lump, inducing diuresis for removing edema is used for goiter, scrofula, testis Ball swelling and pain, phlegm retention oedema.

Bulbus fritillariae cirrhosae, bitter, sweet, cold nature.Return lung, the heart channel of Hang-Shaoyin.Clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, dissipating bind disappear carbuncle.It is dry for lung heat Cough, dry cough lack phlegm, deficiency of yin and overstrain cough, blood-stained sputum, scrofula, acute mastitis, pulmonary abscess.

Rhizome of chuanxiong, property is acrid in flavour and warm in nature, returns liver, gallbladder, the heart channel of Hang-Shaoyin, and blood-activating and qi-promoting, promotes breathing, spasmolysis, antibacterial anti-inflammatory at wind-expelling pain-stopping.

Ramulus euonymi, it is bitter, pungent, it is cold in nature.Return liver, the spleen channel.Blood-breaking promoting menstruation, removing toxicity for detumescence, desinsection.For abdominal mass caking, the heart Abdomen pain, amenorrhoea, dysmenorrhea, metrorrhagia and metrostaxis, postpartum stasis abdominal pain, lochia not under, hernia, joint-running numbness pain, sore swells, injuries from falls as well, Abdominal pain due to enterositosis, burn and scald, venomous snake bite.

Pheretima, taste is salty, cold in nature, returns liver, spleen, bladder meridian, and clearing away heat and relieving the wind syndrome is relievingd asthma, dredging collateral, diuresis, is used for high fever infantile convulsion, hand Foot twitch, dyspnea and cough due to lung-heat, arthralgia, hemiplegia, heat knot renal shutdown.

Dens draconis, puckery are cool in nature.Converge to heart and liver channels.For tranquillizing the mind by relieving convulsion, relieving restlessness heat.It is demented to control frightened epilepsy, dysphoria with smothery sensation is uneasy, insomnia Dreaminess.Frightened epilepsy, insane disease it is mad walk, tie gas under the heart, cannot wheeze.

Rhizoma Anemones Altaicae, acrid flavour, slightly warm in nature.Have one's ideas straightened out, wet, stomach invigorating, removing toxic substances are declared in slit phlegm, wind-dispelling.Control pyreticosis coma and delirium, epilepsy Coma due to blocking of the respiratory system, deafness with qi stagnation, dreaminess amnesia, feeling of stuffiness in chest evil of vomitting, rheumatic arthralgia, sore scabies pyogenic infections.

Scorpio, acrid flavour is mild-natured, return liver warp, and relieve the wind syndrome antispastic is removed obstruction in channels to relieve pain, dispersing pathogen accumulation, is used for liver wind agitation, and spasm is taken out It jerks, child convulsion, middle air port , hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula.

Centipede, acrid flavour are warm-natured.Return liver warp.Relieve the wind syndrome antispastic, removes obstruction in channels to relieve pain, dispersing pathogen accumulation.For liver wind agitation, spasm is taken out It jerks, child convulsion, middle air port , hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula, snakebite and bugbite.

SHENLIUGU, acrid flavour is warm-natured, toxic, return lung, liver, the spleen channel, resolving sputum scattered plot, blood stasis.It coughs, stagnates for phlegm, malaria Disease, menostasis, traumatic injury, carbuncle swells, furunculosis, erysipelas, scald.

Prunella vulgaris, acrid flavour, hardship are cold in nature, return liver, gallbladder channel, clearing liver-fire, improving eyesight, mass dissipating and swelling eliminating, for red eye, swell pain, mesh Pearl nyctalgia, headache and dizziness, scrofula, goiter, acute mastitis, breast illness, swollen breasts.

Sky dragon, taste is salty, cold in nature.Return kidney, Liver Channel.Wind-dispelling, active, dissipating bind.For paralysis due to windstroke, rheumatic arthritis, marrow Inflammation, scrofula, the cancer of the esophagus, lung cancer, primary carcinoma of liver, intestinal cancer etc..

Asparagus fern, sweet in flavor, bitter, cold in nature, return lung, kidney channel, nourishing yin to moisten dryness, clearing lung-heat are promoted the production of body fluid, and dryness of the lung dry cough is used for, and pertussis phlegm is glutinous, Soreness of waist and knee joint, osteopyrexia and fever, Heat Diabetes, pyreticosis saliva wound, dry throat and mouth, dry constipation of intestines.

The root of straight ladybell, sweet in flavor, slight bitter, cold nature.It attaches to the lung and stomach meridians.Nourishing yin and clearing heat, moistening lung for removing phlegm, reinforcing stomach reg fluid.It is long for the deficiency of Yin Cough, consumptive disease are coughed phlegm blood, and cough caused by dryness phlegm is few, abnormal heat sore throat, injury thirst.

Fructus viticis, acrid flavour, hardship, cold nature.Return lung, bladder, Liver Channel.Dispelling wind and heat from the body, head clearing, joint at dehumidifying.Outside Sense headache, polarization intermittent headache, the mesh that swoons is dark, red eyes with many tear, pain, gingivitis, arthritis with fixed pain caused by dampness muscular constricture in mesh eyeball.

Fushen, slightly sweet flavor are mild-natured.Enter the heart, the spleen channel.Calming heart is calmed the nerves, Li Shui.Palpitation with fear of having a guilty conscience is controlled, amnesia is had a sleepless night, frightened epilepsy, Difficult urination.

Cicada slough, it is sweet in flavor, salty, it is cool in nature.Return lung, Liver Channel.Dispelling wind and heat from the body, relieving sore-throat open sound, promoting eruption, removing nebula, Inflammation Zhijing. For anemopyretic cold, warm disease is from the beginning of, pharyngalgia hoarse voice, measles without adequate eruption, rubella itch, cataract, anxious chronic infantile convulsion, tetanus card, Nocturnal fretfulness in infants is uneasy.

Fructus Liquidambaris, bitter are mild-natured.Channel tropism liver and kidney channel.There are dispelling, collateral-activating, Li Shui, the effect of promoting menstruation.For arthralgia, Numb spasm, edema swelling, cream is few, menostasis.

Magnetite, taste is salty, cold in nature.Return liver, the heart, kidney channel.Tranquillizing the mind by relieving convulsion, calming the liver, hearing-improing and eyesight improving, gas of receiving are relievingd asthma.For Insomnia of palpitating with fear is had a dizzy spell, blurring of vision, Hiccough and deaf, kidney deficiency asthma.

Peach kernel, mild-natured, bitter, sweet, return heart, liver, large intestine channel.Promoting blood circulation, relax bowel and defecation is relieving cough and asthma, is used for menostasis Dysmenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, pulmonary abscess acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.

Umbellate pore furgus, it is sweet in flavor, light, it is mild-natured.Return heart, spleen, stomach, lung, kidney channel.Clearing damp and promoting diuresis.Control difficult urination, oedema, diarrhea, leaching It is turbid, leukorrhagia.

The larva of a silkworm with batrytis, acrid flavour is salty, mild-natured.Enter liver, lung, stomach meridian.It expels endogenous wind to relieve convulsion, reducing phlegm and resolving masses.Control apoplectic aphasia, frightened epilepsy, head Wind, sore-throat.Sore throat, scrofula tuberculosis.Wind sore urticaris, erysipelas, mazoitis.

Radix Notoginseng, sweet in flavor, slight bitter is warm-natured, returns liver, stomach meridian, dissipating stasis and stanching bleeding, detumescence ding-tong, for spitting blood, spits blood, bleeding from five sense organs or subcutaneous tissue, Hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, chest and abdomen shouting pain, tumbling and swelling.

Fingered citron, acrid flavour, hardship, acid are warm-natured.Return liver, spleen, stomach, lung channel.There are dispersing stagnated hepatoqi and helmet analgesic, eliminating dampness and eliminating phlegm function Effect.For stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, deficiency of food vomiting, coughing with a lot of sputum.

Radix pseudostellariae, sweet in flavor, slight bitter；It is mild-natured.Returns spleen, lung channel.It replenishes qi to invigorate the spleen, it is promoting production of body fluid and nourishing the lung.Tired for spleen deficiency body, appetite is not Vibration, eak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration and thirst, dryness of the lung dry cough.

Radix Curcumae, acrid flavour, hardship are cold in nature.Return liver, the heart, lung channel.Promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, clear away heart-fire cool blood, normalizing gallbladder to cure jaundice.With In pricking pain in the chest, chest impediment and cardialgia, amenorrhea and algomenorrhea, swollen breasts, pyreticosis coma, epilepsy goes mad, blood-head tells nosebleed, jaundice and reddish urine.

Leech, taste is salty, bitter, mild-natured, return liver warp, blood-breaking promoting menstruation, by stagnation resolvation disease, is used for blood stasis, addiction lump in the abdomen lump in the abdomen, apoplexy Hemiplegia, injury from falling down.

Tortoiseshell, taste is salty sweet, mild-natured, enriching yin, checking exuberance of yang, kidney tonifying, strong bone, controls the deficiency of the kidney yin, and hectic fever due to yin labor heat is spitted blood, bleeding from five sense organs or subcutaneous tissue, long Cough, spermatorrhea, metrorrhagia and metrostaxis, leukorrhagia, pain in the loins, the atrophic debility of bones, wind formation from yin deficiency, protracted dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.

Thallus laminariae, taste is salty, cold in nature.Return liver, stomach, kidney channel.Dissolving phlegm resolving hard lump, inducing diuresis for removing edema.For goiter, scrofula, testis Swelling and pain, phlegm retention oedema.

Rhizoma Atractylodis Macrocephalae, it is bitter, sweet, it is warm-natured；Returns spleen, stomach meridian.Air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.For deficiency-weakness of spleen-QI, Anorexia and loose stool, phlegm retention oedema, exterior deficiency spontaneous perspiration, threatened abortion.

Turtle shell, taste is salty, cold nature, returns liver and kidney channel, and nourishing and suppressing Yang is brought down a fever except steaming, and resolving hard lump is used for fever due to yin deficiency, bone Labor heat is steamed, hyperactivity of yang due to yin deficiency is had a dizzy spell, endogenous deficient wind, menostasis , Disorder lump in the abdomen, chronic malaria, malaria with abdominal mass.

Radix Glycyrrhizae, sweet in flavor, mild-natured, return heart, lung, spleen, stomach meridian are invigorated the spleen and benefited qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, are adjusted With all medicines, be used for weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus, delay Solve drug toxicity, strong.

Further, above-mentioned dens draconis is calcined DENS DRACONIS；Rhizoma Atractylodis Macrocephalae is Rhizoma Atractylodis Macrocephalae preparata；Radix Glycyrrhizae is licorice.

The present invention also provides the preparation methods of the Chinese medicine composition of above-mentioned treatment meningioma, comprising the following steps:

(1) each raw material is weighed by the parts by weight of above-mentioned medicine for oral administration；

(2) it will be added for tortoiseshell, the turtle shell after 98-120 DEG C of decoction 20-30min to after 0-5 DEG C of immersion 60-90min Remaining material in, continue impregnate 60-90min, it is spare；

(3) soaked raw material is decocted, the medicament and the dregs of a decoction of first time is obtained by filtration, it is spare；

(4) water is added into the dregs of a decoction, decocts again, secondary medicament is obtained by filtration；

(5) after the medicament of first time and secondary medicament being mixed to obtain the final product；

Further, decoction described in above-mentioned steps (3) and/or step (4) be 100-120 DEG C decoct to water boiling after drop Temperature decocts 45-55min to 80-100 DEG C.

Further, above-mentioned decoction further includes the operation of stirring, and the operation of stirring is that raw material 4-5 is stirred in decoction process It is secondary.

Usage and dosage, old man is weak, and old sick severe one is divided three days and taken twice daily, and sick less serious case divides between twenty and fifty and body by force It takes within two days, three times a day, breakfast latter hour to one and half.120-150 milliliters of dosage；Lunch latter hour half takes medicine Dosage is 120 milliliters；Latter half dosage of hour of supper is 120-150 milliliters.Meanwhile avoiding seafood, pungent, tobacco and wine, animal food, also Wind sheltering cold and heat heat, room ventilation bright light are needed, it is personal happy, build good living environment.

Specific embodiment

The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common Technical staff's every other embodiment obtained without making creative work belongs to the model that the present invention protects It encloses.

Embodiment 1

The Chinese medicine composition for treating meningioma；

Raw material are as follows: Radix Astragali 25g, arisaema cum bile 10g, non-irrigated tuber of pinellia 15g, seaweed 25g, bulbus fritillariae cirrhosae 25g, Rhizoma Chuanxiong 15g, Ramulus euonymi 25g, pheretima 15g, dens draconis 15g, Rhizoma Anemones Altaicae 25g, scorpio 20g, centipede 2, SHENLIUGU 25g, Prunella vulgaris 15g, sky dragon 10g, day It is winter 15g, the root of straight ladybell 25g, fructus viticis 20g, fushen 25g, cicada slough 10g, Fructus Liquidambaris 25g, magnetite 40g, peach kernel 10g, umbellate pore furgus 15g, white Bombyx batryticatus 25g, Radix Notoginseng 25g, fingered citron 25g, radix pseudostellariae 25g, Radix Curcumae 15g, leech 20g, tortoiseshell 20g, thallus laminariae 25g, Rhizoma Atractylodis Macrocephalae preparata 15g, turtle shell 40g, licorice 20g.

The preparation method comprises the following steps:

(1) each raw material is weighed by above-mentioned quality；

(2) tortoiseshell, the turtle shell after 100 DEG C of decoction 30min are added into the remaining material after 0 DEG C is impregnated 60min, Continue to impregnate 60min, it is spare；

(3) it is 100 DEG C that temperature is kept after decocting 100 DEG C of soaked raw material to water boiling, decocts 55min, during which stirs It mixes 5 times, the medicament and the dregs of a decoction of first time is obtained by filtration, it is spare；

(4) water is added into the dregs of a decoction, it is 100 DEG C that temperature is kept after 100 DEG C of decoction to water boilings, decocts 55min, during which stirs It mixes 5 times, secondary medicament is obtained by filtration；

(5) by the medicament of first time and secondary medicament mix to get.

Embodiment 2

The Chinese medicine composition for treating meningioma；

Raw material are as follows: Radix Astragali 12g, arisaema cum bile 20g, non-irrigated tuber of pinellia 25g, seaweed 15g, bulbus fritillariae cirrhosae 15g, Rhizoma Chuanxiong 25g, Ramulus euonymi 15g, pheretima 25g, dens draconis 25g, Rhizoma Anemones Altaicae 15g, scorpio 10g, centipede 4, SHENLIUGU 15g, Prunella vulgaris 25g, sky dragon 20g, day It is winter 25g, the root of straight ladybell 15g, fructus viticis 10g, fushen 15g, cicada slough 20g, Fructus Liquidambaris 15g, magnetite 20g, peach kernel 20g, umbellate pore furgus 25g, white Bombyx batryticatus 15g, Radix Notoginseng 15g, fingered citron 15g, radix pseudostellariae 15g, Radix Curcumae 25g, leech 10g, tortoiseshell 40g, thallus laminariae 15g, Rhizoma Atractylodis Macrocephalae preparata 25g, turtle shell 20g, licorice 10g.

The preparation method comprises the following steps:

(1) each raw material is weighed by above-mentioned quality；

(2) tortoiseshell, the turtle shell after 98 DEG C of decoction 20min are added into the remaining material after 0 DEG C is impregnated 60min, Continue to impregnate 60min, it is spare；

(3) it is cooled to 85 DEG C after decocting 100 DEG C of soaked raw material to water boiling, decocts 45min, during which stirs 4 times, The medicament and the dregs of a decoction of first time is obtained by filtration, it is spare；

(4) water is added into the dregs of a decoction, is cooled to 85 DEG C after 100 DEG C of decoction to water boilings, decocts 45min, during which stir 4 It is secondary, secondary medicament is obtained by filtration；

(5) by the medicament of first time and secondary medicament mix to get.

Embodiment 3

The Chinese medicine composition for treating meningioma；

Raw material are as follows: raw material are as follows: Radix Astragali 18g, arisaema cum bile 15g, non-irrigated tuber of pinellia 22g, seaweed 20g, bulbus fritillariae cirrhosae 20g, Rhizoma Chuanxiong 20g, Ramulus euonymi 20g, pheretima 20g, dens draconis 20g, Rhizoma Anemones Altaicae 20g, scorpio 15g, centipede 3, SHENLIUGU 20g, Prunella vulgaris 20g, sky dragon 15g, asparagus fern 18g, the root of straight ladybell 20g, fructus viticis 16g, fushen 20g, cicada slough 12g, Fructus Liquidambaris 20g, magnetite 30g, peach kernel 15g, umbellate pore furgus 20g, larva of a silkworm with batrytis 20g, Radix Notoginseng 20g, fingered citron 20g, radix pseudostellariae 20g, Radix Curcumae 20g, leech 15g, tortoiseshell 30g, thallus laminariae 20g, coke Rhizoma Atractylodis Macrocephalae 20g, turtle shell 30g, licorice 15g.

The preparation method comprises the following steps:

(1) each raw material is weighed by above-mentioned quality；

(2) tortoiseshell, the turtle shell after 120 DEG C of decoction 30min are added into the remaining material after 5 DEG C are impregnated 90min, Continue to impregnate 90min, it is spare；

(3) it is cooled to 100 DEG C after decocting 120 DEG C of soaked raw material to water boiling, decocts 55min, during which stirs 5 It is secondary, the medicament and the dregs of a decoction of first time is obtained by filtration, it is spare；

(4) water is added into the dregs of a decoction, is cooled to 100 DEG C after 120 DEG C of decoction to water boilings, decocts 55min, during which stir 4 It is secondary, secondary medicament is obtained by filtration；

(5) by the medicament of first time and secondary medicament mix to get.

Embodiment 4

The Chinese medicine composition for treating meningioma；

Raw material are as follows: raw material are as follows: Radix Astragali 20g, arisaema cum bile 13g, non-irrigated tuber of pinellia 22g, seaweed 17g, bulbus fritillariae cirrhosae 19g, Rhizoma Chuanxiong 22g, Ramulus euonymi 23g, pheretima 16g, dens draconis 23g, Rhizoma Anemones Altaicae 18g, scorpio 12g, centipede 2, SHENLIUGU 22g, Prunella vulgaris 20g, sky dragon 16g, asparagus fern 18g, the root of straight ladybell 23g, fructus viticis 14g, fushen 21g, cicada slough 17g, Fructus Liquidambaris 23g, magnetite 35g, peach kernel 12g, umbellate pore furgus 17g, larva of a silkworm with batrytis 19g, Radix Notoginseng 24g, fingered citron 20g, radix pseudostellariae 16g, Radix Curcumae 17g, leech 16g, tortoiseshell 28g, thallus laminariae 23g, coke Rhizoma Atractylodis Macrocephalae 22g, turtle shell 33g, licorice 10g.

The preparation method comprises the following steps:

(1) each raw material is weighed by above-mentioned quality；

(2) tortoiseshell, the turtle shell after 98 DEG C of decoction 30min are added into the remaining material after 0 DEG C is impregnated 60min, Continue to impregnate 60min, it is spare；

(3) it is cooled to 90 DEG C after decocting 100 DEG C of soaked raw material to water boiling, decocts 55min, during which stirs 5 times, The medicament and the dregs of a decoction of first time is obtained by filtration, it is spare；

(4) water is added into the dregs of a decoction, is cooled to 85 DEG C after 120 DEG C of decoction to water boilings, decocts 55min, during which stir 4 It is secondary, secondary medicament is obtained by filtration；

(5) by the medicament of first time and secondary medicament mix to get.

Embodiment 5

The Chinese medicine composition for treating meningioma；

Raw material is raw material are as follows: Radix Astragali 18g, arisaema cum bile 13g, non-irrigated tuber of pinellia 18g, seaweed 20g, bulbus fritillariae cirrhosae 21g, Rhizoma Chuanxiong 16g, ghost Fletching 15g, pheretima 25g, dens draconis 17g, Rhizoma Anemones Altaicae 23g, scorpio 13g, centipede 4, SHENLIUGU 19g, Prunella vulgaris 25g, sky dragon 14g, asparagus fern 16g, the root of straight ladybell 18g, fructus viticis 16g, fushen 23g, cicada slough 14g, Fructus Liquidambaris 18g, magnetite 26g, peach kernel 14g, umbellate pore furgus 22g, larva of a silkworm with batrytis 20g, Radix Notoginseng 16g, fingered citron 21g, radix pseudostellariae 24g, Radix Curcumae 18g, leech 11g, tortoiseshell 35g, thallus laminariae 25g, coke Rhizoma Atractylodis Macrocephalae 15g, turtle shell 28g, licorice 12g.

The preparation method comprises the following steps:

(1) each raw material is weighed by above-mentioned quality；

(2) tortoiseshell, the turtle shell after 120 DEG C of decoction 20min are added into the remaining material after 0 DEG C is impregnated 90min, Continue to impregnate 90min, it is spare；

(3) it is 100 DEG C that temperature is kept after decocting 100 DEG C of soaked raw material to water boiling, decocts 50min, during which stirs It mixes 5 times, the medicament and the dregs of a decoction of first time is obtained by filtration, it is spare；

(4) water is added into the dregs of a decoction, is cooled to 100 DEG C after 120 DEG C of decoction to water boilings, decocts 55min, during which stir 5 It is secondary, secondary medicament is obtained by filtration；

(5) by the medicament of first time and secondary medicament mix to get.

Clinical test

Function and effect of the invention are further proved below by way of specific case:

Case 1

Meningioma (cholesteatoma recurrence after operation).

Cheng Yusheng, male, 58 years old, Shanxi Province Lucheng City post office worker came to go to a doctor on June 14th, 1999.

Main suit: patient is such as split because suffering from the left ear Hearing of brain tumor (cholesteatoma), headache, recently aggravation.

Present illness history: patient does nuclear-magnetism in 0 hospital of Henan Province Luoyang Chinese People's Liberation Army's First Five-Year Plan May 16 nineteen ninety-five and is total to Vibration, MRI (17163).Left cerebellopontine angle 1.2*2.5*2cm as the result is shown, brain stem and hemisphaerium cerebelli are pressurized.Left side CPA scalp Occupy-place, enhancing and scanning consider that arachnoid cyst possibility is big without reinforcing.

One week after inspection, gamma knife operation is carried out in the institute, continues half a year of taking medicine after operation.In nineteen ninety-five after half a year December 21 was checked in 0 hospital of Luoyang Chinese People's Liberation Army First Five-Year Plan: nuclear magnetic resonance check MRI (1066).

Enhance seen in image: enhancing scanning: former cholesteatoma Gamma knife treatment is postoperative, it has now been found that still may be used left cerebellopontine angle region See irregular abnormal diameter 3*1.5cm size occupying lesion.

It follows the doctor's advice: continuing to take drugs 2 years, not improve, during this period, oneself feel what the state of an illness was increased instead May, be embodied in: 1. left ear Hearing 2. the increasingly fuzzyyer 3. headache of left vision such as split, left side body it is stiff.Immediately It is checked on May 7th, 1998 in hospital general, Ministry of Coal Industry, does nuclear magnetic resonance, No. MRI (42438)；

Seen in head: the visible similar round T1W low signal of left side pontocerebellar crus, T2 high RST shape about 3*3.1 size, boundary Clearly, interior signal is uniform, strengthens after enhancing without obvious, and no abnormality seen signal changes in remaining brain parenchym, ventricular system without expansion, Brain ditch pond is split without broadening, and centerline construction is thickened without displacement, bilateral mucous membrane of maxillary sinus.

Diagnosis: left pontocerebellar crus area benign cystic occupying lesion consideration/zoomylus is big compared with arachnoid cyst possibility, Bilateral maxillary sinusitis.

It is transferred from one hospital to another immediately to Beijing Tiantan Hospital, the multiple hospitals such as Xuan Wu hospital, expert opinion is all unanimously, to implement second Brain tumor esection certainty is less big.Patient visits Ji Jia hospital under the accompanying of relatives, the change for finally selecting a hospital special Tumor ball is taken back and prepares long-term treatment, during treatment, thinks that left leg lands fiber crops, acid, swollen, aconuresis suddenly, stool is dry Knot, night nightmare, insomnia, a variety of symptoms such as facial paralysis, oneself requires traditional Chinese medical herbal treatment, on June 14th, 1999, is in Under the accompanying belonged to, come to go to a doctor.Patient's bodily form is thin, and complexion hardship is held, and headache is intended to split, and left hemisphere fiber crops are swollen, left ear Hearing, left Eye vision is fuzzy, and gum is cold, sour, pain, and nightmare, insomnia, left side body is stiff, aconuresis, dry and hard excrement, and poor appetite, tongue are red Drop, tongue fur it is sticky thicken, slow and sunken pulse and string is puckery.There are history of hypertension, blood glucose history.

Dialectical: liver-yang hyperactivity, the dysfunction of the spleen in transport, knot hinder network into the stasis of blood, phlegm wet.Therapy: calming the liver purging intense heat, dampness removing resolving sputum, dissipating bind Stagnation resolvation, ascending the clear and descending the turbid.

The Chinese medicine composition for treating meningioma in the present invention in embodiment 1 is taken, after treatment in two months, patient symptom It makes moderate progress, headache is lighter, and left vision is more visible, urine is restored, stool is smooth, but other symptoms still have.To consolidate The course for the treatment of continues to take drug of the present invention, and passes through bimestrial treatment, and patient at night sleep is normal, seldom has horrible nightmares, loses Sleep disappear, eye vision makes moderate progress, hearing is slightly better, and the walking of left leg facilitates freely, and it is normal that left face takes out fiber crops, but gum it is cold, It is sour, swollen to still have, pass through trimestral treatment again on the basis of original improvement, the above-mentioned state of an illness turned for the better by and large, in 1999 December 13 is in the attached peaceful hospital magnetic resonance examination of The Medical College of Changzhi, Shanxi: MRI (00031)

Seen in MRI: left side pon, cerebellar peduncle occupy-place are in T1T2 signal, inequality signal, and left side brain stem is slightly pressurized, and the 4th The ventricles of the brain slightly move to right, and compare in May, 1998, have no significant change, in addition, the ventricles of the brain are little, shown arteriae cerebri flow is normal.

CPA space occupying lesion on the left of image, it is proposed that do enhancing scanning.Checked through neurologist, nerve specialist: left pontocerebellar crus occupy-place with Former piece, which compares, to be obviously reduced.Punishment opinion: continue to be treated with Chinese medicine.

For after treatment effect, continue to take or so half a year, after the treatment of the Chinese medicine of nearly one-year age, above-mentioned symptom is complete Portion disappears, and freely, daily life is suitable for patient activity.

From treatment end on May 3,14 days to 2000 June in 1999, between 13 years later, no relapse has no transfer, Through multiple follow-up, it is in a good state of health.

(note) leads oncogenic recurrence proliferation since operation is not thorough brain tumor, and modern medicine is thought from histology: Meningioma belongs to benign tumor, but it is inclined to local infiltration, especially easily immerses endocranium, venous sinus and skull etc., therefore The reason of tumor resection is not easy thoroughly, this is often tumor recurrence.Motherland's medicine thinks: the kidney generating marrow and dominating bone, marrow sea be brain, brain is The internal organs of first mind, Chinese medicine to the understanding of brain tumor with caused by convulsive seizure due to phlegm-fire, pathogenesis with caused by lung, liver,kidney,spleen functional disturbance.Work as spleen Burnt in the wet excessive damage of stomach cold, then the strong fortune of spleen is not normal, accumulatively wet raise phlegm or because exopathogen violates lung, then impairment of dispersing and descending function of the lung, mechanism of qi are obstructed, water Wet to gather in chest diaphragm be phlegm, or because of the insufficiency of the kidney yang, Yang Buhua water, and it is phlegm that water is general, above all phlegm, upper to cover clear key and cause lucid yang failing to raise, turbid Yin does not drop, and hair tonic is brain tumor.According to obstructed, the theory that Enlarged nodes must be resolved of Chinese medicine pain, in conjunction with clinical, dialectical: dredging phlegm stagnation resolvation, invigorating the spleen Stomach function regulating opens strongly fragrant dissipating bind, and warm tonifying brain and kidney, whole to improve, tonification and purgation in combination, and eliminating brain tumor has preferable therapeutic effect.Pass through the sight of this case It examines, relate, treat, traditional Chinese medicine has irreplaceable therapeutic effect in terms of curing this chronic disease of meningioma.

Case 2

Meningioma

Tian Hui, female 72 years old, live Shanghai City Hami road Lane 1940 Room 502, medical to our hospital on May 20th, 1999.

Main suit: patient gave birth to brain tumor more than 7 years, on October 20th, 97 unexpected disease relapse so far, dizzy, nervous, vomiting, Leg hand is numb, cannot stand, nearest aggravation.

Present illness history: patient because second of encephalopathy on May 10th, 1992 Shanghai Tung Wah hospital CT examination report: No. CT 48163, finding: seen in cranium brain enhancing scanning front and back: the visible slightly higher density stove of left brain top, size is about 3.0X3.7X2.0cm, clear border, periphery have no that oedema band CT value is that lesion is shown in about after 46.4-57.6HU (scan56) enhances One it is obvious strengthen, it is slightly crude that CT value is that 91.6HU (scan9) local skull bone is held, substantially with 89.622 and 89.12.20 piece tumour Similar, two telocoele almost symmetries, centerline construction is placed in the middle.

Opinion: brain left parietal lobe brain tumor and 89.6.22 and 89.12.20 piece are substantially similar.

After inspection, in Shanghai, Chinese medicine is taken by Duo Jia institute of traditional Chinese medicine.It sees a doctor at Qian Bowen professor earliest, illness five, six It the patient nursing of layman and is accompanied down between year, body is restored rapidly.But at night on October 20th, 1997, unexpected disease Feelings recurrence headache, dizziness gradually cause nervous, nausea and vomiting, and left face fiber crops are swollen, and left hand takes out fiber crops, and left foot numbness cannot land walking. Speed is to live in Huashan hospital, Shanghai Medical Univ, in progress MRI inspection on November 21st, 1997, No. MRI (225560/046).

Seen in MRI: the visible about 4cm similar round high density shadow of left brain top

Diagnosis: the area Zuo Ding portion's occupy-place, it is believed that it is meningioma,

School requires operative treatment, and family members require conservative therapy (because patient is in a variety of slow diseases for many years) be hospitalized immediately into Row conservative therapy, through the combination of Chinese tradiational and Western medicine more than a year, curative effect has but not significant.Another disease relapse of in mid-May, 1999 patient, It is invited to speed and rushes to Shanghai after inquiring the state of an illness, note patient because former disease recurrence causes nausea and vomiting, third day causes trick numb Wooden, left face pumping fiber crops, left eye blepharoptosis, vision misplace, are on tenterhooks, sweaing all over, tongue red drop tongue fur is sticky, the heavy string late of pulse condition Carefully, patient suffers from pulmonary heart disease, the epilepsy of many years.

It is dialectical: speen-kidney dificiency, phlegm go out on disturb clear key, member, phlegm wet resistance network on liver-yang.Therapy: strengthening the spleen and stomach, kidney tonifying calming the liver, Checking exuberance of yang resolving sputum and strongly fragrant dredging collateral.

After taking Chinese medicine composition one month that treats meningioma in the present invention in embodiment 1, patient experiences stable disease, not There is uncomfortable reflection.Continue to treat by original side, but through it is trimestral it is patient show consideration for nursing for treating, the state of an illness is improved, headache, dizzy Dizzy symptom is mitigated, and night sweat obviously disappears, left face takes out fiber crops in interim (Monday is to twice once in a while), numbness in hands and feet, depending on Feel dislocation, aphasia slightly improves earlier above, but sitting shakiness does not change, and still with top medication, adapted forges dens draconis, black small Beans, black machine fruit, rhizoma polygonati, each 10 grams of American Ginseng cook gruel and take.Conditioning and treating through three wheat harvesting periods again, patient can hand over people opposite It talks, eye view dislocation disappears, and can lift crutch can descend ground independent ambulation.Pale tongue tongue fur falls white, deep thready pulse and string.

It is checked on October 20th, 1999 in Shanghai Medical Univ: CT examination enhanced CT number: 271326, check knot Fruit: left top occupy-place considers meningioma.

Institute expert checks the knurl compared with 97 years photos and is obviously reduced.

On November 17th, 1999 receives the autograph letter that patient mails.According to the gradually improvement of conditions of patients, continue medication half Year is to consolidate the course for the treatment of.

By the treatment of front and back only one-year age, the above-mentioned illness of patient is substantially achieved effective control and cures.From Start on May 20th, 1999 after treating to treatment end on March 18th, 2000 between 16 years, no relapse has no transfer, repeatedly Follow-up is in a good state of health.

There is cranium pressure and increase disease in (note) one, brain tumor occupy-place, as headache is such as split, dizziness causes binocular oedema prominent, nauseous Vomiting occurs with slight brain tumor.Two, cranium pressure increases the appearance of disease, in succession with the disorder of each system function: such as hemiplegia is lost Language, strabismus, otosis, expansion of the molten product in third fourth ventricle etc..Modern medicine grade are as follows: operation is the prerequisite of tumor radical cure, It secondly is radiotherapy chemotherapy and biological therapy, the limitation of doctor trained in Western medicine.Patient is originally suffered from brain tumor 7 years, there is pulmonary heart disease history, epilepsy Medical history selective therapy is the road sought survival.And the organic conception of Chinese medicine is flexible and diversity.Be willing to those the old,weak,sick and disableds and Domestic conditions extremely poor answers the one's own therapeutic modality of more options, multinomial selection.Chinese medicine encephalopathy is Chinese Internal Medicine An important branch, it research and clinical treatment in have huge potential.Also signify that traditional Chinese medicine goes to the world simultaneously, Move towards following inexorable trend.

Claims

1. a kind of Chinese medicine composition for treating meningioma, which is characterized in that be composed of the following raw materials by weight: 12-25 parts of Radix Astragali, 10-20 parts of arisaema cum bile, non-irrigated 15-25 parts of the tuber of pinellia, 15-25 parts of seaweed, 15-25 parts of bulbus fritillariae cirrhosae, 15-25 parts of Rhizoma Chuanxiong, Ramulus euonymi 15-25 Part, 15-25 parts of pheretima, 15-25 parts of dens draconis, 15-25 parts of Rhizoma Anemones Altaicae, 10-20 parts of scorpio, centipede 2-4 item, 15-25 parts of SHENLIUGU, 15-25 parts of Prunella vulgaris, 10-20 parts of sky dragon, 15-25 parts of asparagus fern, 15-25 parts of the root of straight ladybell, 10-20 parts of fructus viticis, 15-25 parts of fushen, 10-20 parts of cicada slough, 15-25 parts of Fructus Liquidambaris, 20-40 parts of magnetite, 10-20 parts of peach kernel, 15-25 parts of umbellate pore furgus, 15-25 parts of the larva of a silkworm with batrytis, 15-25 parts of Radix Notoginseng, 15-25 parts of fingered citron, 15-25 parts of radix pseudostellariae, 15-25 parts of Radix Curcumae, 10-20 parts of leech, 20-40 parts of tortoiseshell, 15-25 parts of thallus laminariae, 15-25 parts of Rhizoma Atractylodis Macrocephalae, 20-40 parts of turtle shell, 10-20 parts of Radix Glycyrrhizae.

2. a kind of Chinese medicine composition for treating meningioma according to claim 1, which is characterized in that the dens draconis is to forge dragon Tooth；The Rhizoma Atractylodis Macrocephalae is Rhizoma Atractylodis Macrocephalae preparata；The Radix Glycyrrhizae is licorice.

3. a kind of preparation method of the Chinese medicine composition for the treatment of meningioma as claimed in claim 1 or 2, which is characterized in that including Following steps:

(1) parts by weight as described in claim 1 or 2 weigh each raw material；

(2) tortoiseshell, the turtle shell after decoction are added into the remaining material after impregnating, continue to impregnate, it is spare；

(5) after the medicament of first time and secondary medicament being mixed to obtain the final product.

4. a kind of preparation method of Chinese medicine composition for treating meningioma according to claim 3, which is characterized in that step (2) tortoiseshell described in, turtle shell decoction method be 98-120 DEG C of decoction 20-30min.

5. a kind of preparation method of Chinese medicine composition for treating meningioma according to claim 3, which is characterized in that step (2) remaining material described in after impregnating is the raw material after 0-5 DEG C is impregnated 60-90min.

6. a kind of preparation method of Chinese medicine composition for treating meningioma according to claim 3, which is characterized in that step (2) continue to impregnate described in continue to impregnate 60-90min.

7. a kind of preparation method of Chinese medicine composition for treating meningioma according to claim 3, which is characterized in that step (3) and/or decoction described in step (4) is is cooled to 80-100 DEG C after 100-120 DEG C of decoction to water boiling, decocts 45- 55min。

8. a kind of preparation method of Chinese medicine composition for treating meningioma according to claim 7, which is characterized in that described Decoction further includes the operation of stirring, and the operation of the stirring is to stir raw material 4-5 times in decoction process.