CN110960460A - 一种冻干粉溶酶液及其制作工艺 - Google Patents

一种冻干粉溶酶液及其制作工艺 Download PDF

Info

Publication number
CN110960460A
CN110960460A CN201911321596.4A CN201911321596A CN110960460A CN 110960460 A CN110960460 A CN 110960460A CN 201911321596 A CN201911321596 A CN 201911321596A CN 110960460 A CN110960460 A CN 110960460A
Authority
CN
China
Prior art keywords
extract
raw materials
ceramide
glycerol
main pot
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201911321596.4A
Other languages
English (en)
Inventor
冯斌斌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhejiang Runhe Biology Technology Co ltd
Original Assignee
Zhejiang Runhe Biology Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhejiang Runhe Biology Technology Co ltd filed Critical Zhejiang Runhe Biology Technology Co ltd
Priority to CN201911321596.4A priority Critical patent/CN110960460A/zh
Publication of CN110960460A publication Critical patent/CN110960460A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A61K8/894Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • A61K8/9711Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • A61K8/9717Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/84Products or compounds obtained by lyophilisation, freeze-drying

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cosmetics (AREA)

Abstract

本发明涉及化妆品技术领域,尤其是一种冻干粉溶酶液及其制作工艺,由下述质量配比的组分制备而成:甲基丙二醇:3‑5%,甘油:2‑4%,双甘油:1‑3%,甜菜碱:2‑4%,甘油聚醚‑26:1‑3%,双丙甘醇:1‑3%,双‑PEG‑15甲基醚聚二甲基硅氧烷:0.1‑2%,甘油葡糖苷:0.2‑0.6%,对羟基苯乙酮:0.2‑0.5%,FUCOSORB提取物:0.2‑0.5%,Lysofix乳化剂:0.1‑0.3%,苯氧乙醇:0.16‑0.19%,甘草酸二钾:0.08‑0.12%,黄原胶:0.08‑0.12%,Symdiol68:0.06‑0.10%,EDTA二钠:0.01‑0.05%,透明质酸钠:0.01‑0.03%,寡肽‑1:0.01‑0.03%,寡肽‑3:0.01‑0.03%,积雪草提取物:0.01‑0.03%,神经酰胺:0.01‑0.03%,根据上述质量配比后余量为去离子水,本发明具有更好的保湿锁水、祛皱抗衰、紧致肌肤、舒缓修复的作用。

Description

一种冻干粉溶酶液及其制作工艺
技术领域
本发明涉及化妆品技术领域,具体领域为一种冻干粉溶酶液及其制作工艺。
背景技术
冻干粉是指在真空条件下冷冻干燥的无菌粉,是一种有修复作用的美容用品。但是一般的冻干粉作用相对单一,无法同时达到细腻肤质、修复痘印、祛除皱纹、延缓衰老、修复角质层、保湿锁水、抗衰修复等功效,并且长期使用对肌肤会带来一定的损伤。
寡肽-1为甘氨酸、组氨酸和赖氨酸组成的合成肽,作为皮肤调理剂使用。
寡肽-3由2-6个氨基酸组成的小分子,能直接有效的被细胞吸收利用,迅速补充胶原蛋白,从而起到很好的调理作用,如促进新陈代谢,刺激细胞再生,增殖、新生胶原,成效较慢,但安全性较高。
甘油是食品级无色无味透明黏稠液体,无臭,有暖甜味。可用作溶剂,润滑剂,药剂和甜味剂。
发明内容
本发明的目的在于提供一种冻干粉溶酶液及其制作工艺,以解决现有技术中冻干粉制剂不适用于任何肤质,且制造复杂繁琐的问题。
为实现上述目的,本发明提供如下技术方案:一种冻干粉溶酶液,由下述质量配比的组分制备而成:
甲基丙二醇:3-5%,甘油:2-4%,双甘油:1-3%,甜菜碱:2-4%,甘油聚醚-26:1-3%,双丙甘醇:1-3%,双-PEG-15甲基醚聚二甲基硅氧烷:0.1-2%,甘油葡糖苷:0.2-0.6%,对羟基苯乙酮:0.2-0.5%,FUCOSORB提取物:0.2-0.5%,Lysofix乳化剂:0.1-0.3%,苯氧乙醇:0.16-0.19%,甘草酸二钾:0.08-0.12%,黄原胶:0.08-0.12%,Symdiol68:0.06-0.10%,EDTA二钠:0.01-0.05%,透明质酸钠:0.01-0.03%,寡肽-1:0.01-0.03%,寡肽-3:0.01-0.03%,积雪草提取物:0.01-0.03%,神经酰胺:0.01-0.03%,根据上述质量配比后余量为去离子水。
优选的,所述的FUCOSORB提取物由山梨醇、水、皱波角叉菜提取物、钩沙菜提取物、拟石花菜提取物、钝马尾藻提取物和齿缘墨角藻提取物组合而成。
优选的,所述的Lysofix乳化剂由甘油和野大豆籽提取物组合而成。
优选的,所述的积雪草提取物由水、甘油、积雪草提取物混合而成。
优选的,所述的神经酰胺由神经酰胺3、神经酰胺6II、神经酰胺1、植物鞘氨醇、胆甾醇、月桂酰乳酰乳酸钠、卡波姆和黄原胶混合制成。
为实现上述产品,本发明还提供如下技术方案:一种冻干粉溶酶液的制作工艺,其步骤为:
(1)将原料去离子水、甲基丙二醇、甘油、双甘油、甜菜碱、甘油聚醚-26、双-PEG-15甲基醚聚二甲基硅氧烷、甘草酸二钾、黄原胶、EDTA二钠、透明质酸钠放入主锅中:
(2)对主锅中的原料进行搅拌并同时进行加热,将主锅中的原料进行溶解;
(3)将原料双丙甘醇、对羟基苯乙酮、苯氧乙醇、Symdiol 68进行混合水浴加热,并搅拌加热至完全溶解;
(4)将主锅中溶解的原料搅拌降温至45-50℃,然后加入步骤(3)中混合溶解的原料;
(5)根据步骤(4),同时在主锅中加入原料甘油葡糖苷、FUCOSORB提取物、Lysofix乳化剂、寡肽-1、寡肽-3、积雪草提取物、神经酰胺,继续搅拌冷却;
(6)在主锅中原料冷却到预设温度后,通过滤网过滤出料。
优选的,根据步骤(2),主锅加热温度为75-80℃,主锅内原料搅拌加热至溶解为透明即可。
优选的,根据步骤(3),水浴加热的温度为65-75℃。
优选的,根据步骤(6),其搅拌冷却温度至37-40℃后进行过滤出料。
优选的,所述的滤网为1um滤网。。
与现有技术相比,本发明的有益效果是:具有更好的保湿锁水、祛皱抗衰、紧致肌肤、舒缓修复的作用;
本发明中透明质酸钠又称玻尿酸钠,属于肌肤调理剂,是一种酸性粘多糖,天然存在于角膜皮中,可吸收其本身重量1000倍水分,以达到通过保留皮肤水分、阻止水分经表皮流失,以及当皮肤受到损伤时的屏障修复,令皮肤使用后不会感到干燥,增加光泽,它可以改善皮肤营养代谢,使皮肤柔、光滑、去皱、增加弹性、防止衰老,在保湿的同时又是良好的透皮吸收促进剂。与其他营养成分配合使用,可以起到促进营养吸收的更理想效果。
本发明中寡肽-1(EGF),是人体内的一种活性物质,由53个氨基组成的活性多肽。能够促进细胞的增殖分化,可直接作用于基底细胞加速健康新细胞的生成,从而把受损的角质细胞层快速顶出来,形成健康的排列规则整齐的角质层。EGF能与人体内各种酶形成良好的协调效应。最初的EGF主要被运用于医学领域,主要用于促进受损表皮的修复与再生,如治疗烧伤、烫伤等。
本发明中寡肽-3,能直接有效的被细胞吸收利用,迅速补充胶原蛋白,从而起到很好的调理作用,如促进新陈代谢,刺激细胞再生,增殖、新生胶原,成效较慢,但安全性较高。
具体实施方式
下面对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
本发明提供一种技术方案:一种冻干粉溶酶液,由下述质量配比的组分制备而成:
甲基丙二醇:3-5%,甘油:2-4%,双甘油:1-3%,甜菜碱:2-4%,甘油聚醚-26:1-3%,双丙甘醇:1-3%,双-PEG-15甲基醚聚二甲基硅氧烷:0.1-2%,甘油葡糖苷:0.2-0.6%,对羟基苯乙酮:0.2-0.5%,FUCOSORB提取物:0.2-0.5%,Lysofix乳化剂:0.1-0.3%,苯氧乙醇:0.16-0.19%,甘草酸二钾:0.08-0.12%,黄原胶:0.08-0.12%,Symdiol68:0.06-0.10%,EDTA二钠:0.01-0.05%,透明质酸钠:0.01-0.03%,寡肽-1:0.01-0.03%,寡肽-3:0.01-0.03%,积雪草提取物:0.01-0.03%,神经酰胺:0.01-0.03%,根据上述质量配比后余量为去离子水。
所述的FUCOSORB提取物由山梨醇、水、皱波角叉菜提取物、钩沙菜提取物、拟石花菜提取物、钝马尾藻提取物和齿缘墨角藻提取物组合而成。
所述的Lysofix乳化剂由甘油和野大豆籽提取物组合而成。
所述的Symdiol 68由1,2-己二醇、辛甘醇组合而成。
所述的积雪草提取物由水、甘油、积雪草提取物混合而成。
所述的神经酰胺由神经酰胺3、神经酰胺6II、神经酰胺1、植物鞘氨醇、胆甾醇、月桂酰乳酰乳酸钠、卡波姆和黄原胶混合制成。
一种冻干粉溶酶液的制作工艺,其步骤为:
(1)将原料去离子水、甲基丙二醇、甘油、双甘油、甜菜碱、甘油聚醚-26、双-PEG-15甲基醚聚二甲基硅氧烷、甘草酸二钾、黄原胶、EDTA二钠、透明质酸钠放入主锅中:
(2)对主锅中的原料进行搅拌并同时进行加热,将主锅中的原料进行溶解;
(3)将原料双丙甘醇、对羟基苯乙酮、苯氧乙醇、Symdiol 68进行混合水浴加热,并搅拌加热至完全溶解;
(4)将主锅中溶解的原料搅拌降温至45-50℃,然后加入步骤(3)中混合溶解的原料;
(5)根据步骤(4),同时在主锅中加入原料甘油葡糖苷、FUCOSORB提取物、Lysofix乳化剂、寡肽-1、寡肽-3、积雪草提取物、神经酰胺,继续搅拌冷却;
(6)在主锅中原料冷却到预设温度后,通过滤网过滤出料。
根据步骤(2),主锅加热温度为75-80℃,主锅内原料搅拌加热至溶解为透明即可。
根据步骤(3),水浴加热的温度为65-75℃。
根据步骤(6),其搅拌冷却温度至37-40℃后进行过滤出料。
所述的滤网为1um滤网。
根据本发明的内容,具有如下表产品实施内容:
Figure BDA0002327290150000051
Figure BDA0002327290150000061
Figure BDA0002327290150000071
Figure BDA0002327290150000081
根据上表的原料配比进行下述的产品工艺生产:
1.将原料1、2、3、4、5、6、8、14、15、17、18加入主锅中,搅拌加热至75-80℃,溶解至透明;
2.将原料7、10、13、16水浴加热(65-75℃)搅拌加热至完全溶解,备用;
3.主锅搅拌降温至45-50℃,加入预先处理的步骤2原料和原料9、11、12、19、20、21、22,继续搅拌冷却至38℃;
4.将冷却后的原料通过1um滤网过滤出料。
尽管已经示出和描述了本发明的实施例,对于本领域的普通技术人员而言,可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型,本发明的范围由所附权利要求及其等同物限定。

Claims (10)

1.一种冻干粉溶酶液,其特征在于:由下述质量配比的组分制备而成:
甲基丙二醇:3-5%,甘油:2-4%,双甘油:1-3%,甜菜碱:2-4%,甘油聚醚-26:1-3%,双丙甘醇:1-3%,双-PEG-15甲基醚聚二甲基硅氧烷:0.1-2%,甘油葡糖苷:0.2-0.6%,对羟基苯乙酮:0.2-0.5%,FUCOSORB提取物:0.2-0.5%,Lysofix乳化剂:0.1-0.3%,苯氧乙醇:0.16-0.19%,甘草酸二钾:0.08-0.12%,黄原胶:0.08-0.12%,Symdiol 68:0.06-0.10%,EDTA二钠:0.01-0.05%,透明质酸钠:0.01-0.03%,寡肽-1:0.01-0.03%,寡肽-3:0.01-0.03%,积雪草提取物:0.01-0.03%,神经酰胺:0.01-0.03%,根据上述质量配比后余量为去离子水。
2.根据权利要求1所述的一种冻干粉溶酶液,其特征在于:所述的FUCOSORB提取物由山梨醇、水、皱波角叉菜提取物、钩沙菜提取物、拟石花菜提取物、钝马尾藻提取物和齿缘墨角藻提取物组合而成。
3.根据权利要求1所述的一种冻干粉溶酶液,其特征在于:所述的Lysofix乳化剂由甘油和野大豆籽提取物组合而成。
4.根据权利要求1所述的一种冻干粉溶酶液,其特征在于:所述的积雪草提取物由水、甘油、积雪草提取物混合而成。
5.根据权利要求1所述的一种冻干粉溶酶液,其特征在于:所述的神经酰胺由神经酰胺3、神经酰胺6II、神经酰胺1、植物鞘氨醇、胆甾醇、月桂酰乳酰乳酸钠、卡波姆和黄原胶混合制成。
6.根据权利要求1所述的一种冻干粉溶酶液的制作工艺,其特征在于:其步骤为:
(1)将原料去离子水、甲基丙二醇、甘油、双甘油、甜菜碱、甘油聚醚-26、双-PEG-15甲基醚聚二甲基硅氧烷、甘草酸二钾、黄原胶、EDTA二钠、透明质酸钠放入主锅中:
(2)对主锅中的原料进行搅拌并同时进行加热,将主锅中的原料进行溶解;
(3)将原料双丙甘醇、对羟基苯乙酮、苯氧乙醇、Symdiol 68进行混合水浴加热,并搅拌加热至完全溶解;
(4)将主锅中溶解的原料搅拌降温至45-50℃,然后加入步骤(3)中混合溶解的原料;
(5)根据步骤(4),同时在主锅中加入原料甘油葡糖苷、FUCOSORB提取物、Lysofix乳化剂、寡肽-1、寡肽-3、积雪草提取物、神经酰胺,继续搅拌冷却;
(6)在主锅中原料冷却到预设温度后,通过滤网过滤出料。
7.根据权利要求6所述的一种冻干粉溶酶液的制作工艺,其特征在于:根据步骤(2),主锅加热温度为75-80℃,主锅内原料搅拌加热至溶解为透明即可。
8.根据权利要求6所述的一种冻干粉溶酶液的制作工艺,其特征在于:根据步骤(3),水浴加热的温度为65-75℃。
9.根据权利要求6所述的一种冻干粉溶酶液的制作工艺,其特征在于:根据步骤(6),其搅拌冷却温度至37-40℃后进行过滤出料。
10.根据权利要求9所述的一种冻干粉溶酶液的制作工艺,其特征在于:所述的滤网为1um滤网。
CN201911321596.4A 2019-12-20 2019-12-20 一种冻干粉溶酶液及其制作工艺 Pending CN110960460A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911321596.4A CN110960460A (zh) 2019-12-20 2019-12-20 一种冻干粉溶酶液及其制作工艺

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911321596.4A CN110960460A (zh) 2019-12-20 2019-12-20 一种冻干粉溶酶液及其制作工艺

Publications (1)

Publication Number Publication Date
CN110960460A true CN110960460A (zh) 2020-04-07

Family

ID=70035367

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201911321596.4A Pending CN110960460A (zh) 2019-12-20 2019-12-20 一种冻干粉溶酶液及其制作工艺

Country Status (1)

Country Link
CN (1) CN110960460A (zh)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105326678A (zh) * 2015-10-28 2016-02-17 嘉兴市蝶柔化妆品有限公司 一种多效神经酰胺面霜
CN107582478A (zh) * 2017-09-07 2018-01-16 蝶柔化妆品(浙江)有限公司 一种清爽滋润霜
CN107595650A (zh) * 2017-09-22 2018-01-19 佛山市奥姿美生物科技有限公司 一种含有海绵微针可促进透皮吸收的化妆品组合物
CN108514541A (zh) * 2018-05-10 2018-09-11 广州珈源日化用品有限公司 一种含寡肽、神经酰胺及甘油葡糖苷修复肌肤屏障精华液
CN108721197A (zh) * 2018-08-17 2018-11-02 广东丸美生物技术股份有限公司 一种具有改善皮肤毛孔和长效保湿功效的组合物及其应用
CN108785241A (zh) * 2018-09-17 2018-11-13 黛倾城健康科技有限公司 一种小分子阿胶精华抗衰面膜
CN109820769A (zh) * 2019-03-14 2019-05-31 上海新高姿化妆品有限公司 一种具有保湿和舒缓功效的化妆水及其制备方法
CN109998986A (zh) * 2019-04-22 2019-07-12 浙江贡盏科技有限公司 一种二裂酵母冻干粉制剂及其制备方法

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105326678A (zh) * 2015-10-28 2016-02-17 嘉兴市蝶柔化妆品有限公司 一种多效神经酰胺面霜
CN107582478A (zh) * 2017-09-07 2018-01-16 蝶柔化妆品(浙江)有限公司 一种清爽滋润霜
CN107595650A (zh) * 2017-09-22 2018-01-19 佛山市奥姿美生物科技有限公司 一种含有海绵微针可促进透皮吸收的化妆品组合物
CN108514541A (zh) * 2018-05-10 2018-09-11 广州珈源日化用品有限公司 一种含寡肽、神经酰胺及甘油葡糖苷修复肌肤屏障精华液
CN108721197A (zh) * 2018-08-17 2018-11-02 广东丸美生物技术股份有限公司 一种具有改善皮肤毛孔和长效保湿功效的组合物及其应用
CN108785241A (zh) * 2018-09-17 2018-11-13 黛倾城健康科技有限公司 一种小分子阿胶精华抗衰面膜
CN109820769A (zh) * 2019-03-14 2019-05-31 上海新高姿化妆品有限公司 一种具有保湿和舒缓功效的化妆水及其制备方法
CN109998986A (zh) * 2019-04-22 2019-07-12 浙江贡盏科技有限公司 一种二裂酵母冻干粉制剂及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
戴晓钟: "《中国科学美容大典》", 28 February 2002, 人民军医出版社 *
王建新: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 *

Similar Documents

Publication Publication Date Title
CN108113914B (zh) 一种不添加香精和防腐剂的精华霜及其制备方法
CN101152138B (zh) 一种具有祛除妊娠纹功效的化妆制品及其制备方法
WO2014117316A1 (zh) 多功能芦荟胶及其制备方法
CN106236675B (zh) 一种具有保湿和抗衰老功效的护肤基质及其制备与应用
CN104666114A (zh) 一种除皱抗衰、活化肌肤、淡化疤痕修复精华液及其制备方法
CN110478305A (zh) 一种羊胎素提取物的制备工艺及其应用
CN110917055A (zh) 一种寡肽修护精华液及其制作工艺
CN103585097A (zh) 一种白及多糖载表皮生长因子复合物及其制备方法和应用
CN110787100A (zh) 抗敏舒肤精华液及其制备方法
CN103479567A (zh) 表皮生长因子复合脂质体及其制备方法和应用
CN111358704A (zh) 一种深层修复抗衰老的组合物及其制备方法和应用
CN111012733B (zh) 一种豆腐柴乳酸敷面剂
CN114288202A (zh) 一种具有抗衰老作用的蚕丝胶蛋白组合物及其制备方法
CN112716842A (zh) 一种具有长效保湿效果的有机保湿霜及其制备方法
CN110960460A (zh) 一种冻干粉溶酶液及其制作工艺
CN103599054B (zh) 含花生蛋白多肽的面膜及其制备方法
CN114392211A (zh) 一种二裂酵母冻干粉组合物及其制备方法
CN114652628A (zh) 一种美胸美体、增强肌肤免疫屏障的抗衰霜及制备方法
CN114306204A (zh) 一种纯天然螺旋藻多肽面膜及其制备方法
CN108853369B (zh) 天然植物抗菌液PAMs水凝胶贴剂的制备方法及应用
CN113057914A (zh) 保湿舒缓喷雾
CN101953757A (zh) 一种冻干凝胶化妆品及其制备方法和应用
CN111617020A (zh) 一种基于海洋生物的美容敷料组合物及其制备方法
CN110917324A (zh) 一种医用冷敷贴及其制备方法
CN118021691B (zh) 一种深度补水的化妆品组合物及其制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20200407