CN110951738B - 猪hdac2基因的表达抑制剂及其应用 - Google Patents
猪hdac2基因的表达抑制剂及其应用 Download PDFInfo
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- CN110951738B CN110951738B CN201911338990.9A CN201911338990A CN110951738B CN 110951738 B CN110951738 B CN 110951738B CN 201911338990 A CN201911338990 A CN 201911338990A CN 110951738 B CN110951738 B CN 110951738B
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
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CN110951738A CN110951738A (zh) | 2020-04-03 |
CN110951738B true CN110951738B (zh) | 2021-10-15 |
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Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102271763A (zh) * | 2008-12-03 | 2011-12-07 | 麻省理工学院 | 抑制hdac2以促进记忆 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
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US8357666B2 (en) * | 2005-08-01 | 2013-01-22 | Nupotential, Inc. | Reprogramming a cell by inducing a pluripotent gene through RNA interference |
AU2009233845A1 (en) * | 2008-04-07 | 2009-10-15 | Nupotential, Inc. | Reprogramming a cell by inducing a pluripotent gene through use of a small molecule modulator |
US11535824B2 (en) * | 2015-10-29 | 2022-12-27 | Sung Kwang Medical Foundation | Nuclear transfer |
CN105543230A (zh) * | 2016-03-02 | 2016-05-04 | 华南农业大学 | 一种基于抑制H3K9me3甲基化的提高猪克隆效率的方法 |
CN107475181B (zh) * | 2017-09-30 | 2021-03-02 | 中国农业大学 | 未成熟卵母细胞的体外成熟培养液及其应用 |
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102271763A (zh) * | 2008-12-03 | 2011-12-07 | 麻省理工学院 | 抑制hdac2以促进记忆 |
Non-Patent Citations (10)
Title |
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Effects of DNMT1 and HDAC Inhibitors on Gene-Specific Methylation Reprogramming during Porcine Somatic Cell Nuclear Transfer;Weihua Xu et al.;《PLOS ONE》;20130531;第8卷(第5期);全文 * |
Essential roles of HDAC1 and 2 in lineage development and genome-wide DNA methylation during mouse preimplantation development;Panpan Zhao et al.;《EPIGENETICS》;20190912;第15卷(第4期);摘要 * |
Genbank:XM_001925318.6;Genbank;《Genbank》;20170513;全文 * |
Histone Deacetylase Inhibitors Improve In Vitro and In Vivo Developmental Competence of Somatic Cell Nuclear Transfer Porcine Embryos;Jianguo Zhao et al.;《CELLULAR REPROGRAMMING》;20101231;第12卷(第1期);全文 * |
Improved early development of porcine cloned embryos by treatment with quisinostat, a potent histone deacetylase inhibitor;Anukul TAWEECHAIPAISANKUL et al.;《Journal of Reproduction and Development》;20181227;第65卷(第2期);摘要 * |
去乙酰化抑制剂对五指山小型猪;康锦丹;《中国博士学位论文全文数据库 农业科技辑》;20130115;全文 * |
干扰HDAC2基因对小鼠早期胚胎组蛋白修饰的影响;申琦元;《中国优秀硕士学位论文全文数据库 基础科学辑》;20130115;全文 * |
王张凡.K228对猪体细胞生长及克隆胚胎体外发育的影晌.《中国优秀硕士学位论文全文数据库 基础科学辑》.2016, * |
组蛋白去乙酰化抑制剂对猪克隆胚胎核重编程的影响;金龙;《中国博士学位论文全文数据库 基础科学辑》;20190115;全文 * |
组蛋白去乙酰化酶抑制剂Oxamflatin对猪体细胞克隆胚胎体外发育率的影响;侯黎明;《中国博士学位论文全文数据库 农业科技辑》;20171215;全文 * |
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Inventor after: Wu Zhenfang Inventor after: Cai Gengyuan Inventor after: Wang Xingwang Inventor after: Li Zicong Inventor after: Wu Xiao Inventor after: Zhao Hua Xing Inventor after: Yang Liusong Inventor before: Wu Zhenfang Inventor before: Cai Gengyuan Inventor before: Wang Xingwang Inventor before: Li Zicong Inventor before: Wu Xiao Inventor before: Zhao Hua Xing Inventor before: Yang Liusong |
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