CN110938604B - 重组单纯疱疹病毒2(hsv-2)疫苗载体 - Google Patents

重组单纯疱疹病毒2(hsv-2)疫苗载体 Download PDF

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CN110938604B
CN110938604B CN201911344961.3A CN201911344961A CN110938604B CN 110938604 B CN110938604 B CN 110938604B CN 201911344961 A CN201911344961 A CN 201911344961A CN 110938604 B CN110938604 B CN 110938604B
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hsv
glycoprotein
recombinant
infection
herpes simplex
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CN110938604A (zh
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W·雅各布
P·A·冈萨雷斯穆诺茨
B·赫罗尔德
C·佩特罗
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Albert Einstein College of Medicine
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/087Herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
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    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
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    • C12N2710/16011Herpesviridae
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    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641Use of virus, viral particle or viral elements as a vector
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    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16671Demonstrated in vivo effect

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CN201911344961.3A 2014-03-03 2015-03-02 重组单纯疱疹病毒2(hsv-2)疫苗载体 Active CN110938604B (zh)

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US201461946965P 2014-03-03 2014-03-03
US61/946,965 2014-03-03
US201462080663P 2014-11-17 2014-11-17
US62/080,663 2014-11-17
PCT/US2015/018272 WO2015134368A2 (en) 2014-03-03 2015-03-02 Recombinant herpes simplex virus 2 (hsv-2) vaccine vectors
CN201580022222.6A CN106456805B (zh) 2014-03-03 2015-03-02 重组单纯疱疹病毒2(hsv-2)疫苗载体
CN201911344961.3A CN110938604B (zh) 2014-03-03 2015-03-02 重组单纯疱疹病毒2(hsv-2)疫苗载体

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JP6652497B2 (ja) 2014-03-03 2020-02-26 アルバート アインシュタイン カレッジ オブ メディシン 組換え単純ヘルペスウィルス2(hsv−2)ワクチンベクター
CN119523872A (zh) 2018-04-27 2025-02-28 克里斯托生物技术股份有限公司 用于美容性应用的编码一种或多种美容蛋白的重组核酸
IL278294B2 (en) * 2018-05-01 2025-01-01 Albert Einstein College Medicine HSV-2-DELTA-gD vaccines and methods for their production and use
WO2020056411A1 (en) * 2018-09-14 2020-03-19 Excell Biotech, Llc Recombinant herpes simplex virus 1 (hsv-1)
EP3866846A4 (en) * 2018-10-17 2022-08-31 Albert Einstein College of Medicine METHOD OF INCREASING ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY (ADCC)
CA3124523A1 (en) * 2019-01-03 2020-07-09 Albert Einstein College Of Medicine Passive transfer of immunity using recombinant herpes simplex virus 2 (hsv-2) vaccine vectors
WO2021207348A1 (en) * 2020-04-07 2021-10-14 Albert Einstein College Of Medicine Method of treating and preventing ocular disease with hsv-2 delta gd
AU2021281314A1 (en) * 2020-05-29 2022-12-22 Albert Einstein College Of Medicine Methods of using HSV-2 single cycle virus delta-gD and HSV-2 recombinant glycoprotein D
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US20250222112A1 (en) * 2022-10-14 2025-07-10 Arizona Board Of Regents On Behalf Of Arizona State University Recombinant immune complexes targeting herpes simplex virus
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US10391165B2 (en) 2019-08-27
US10751411B2 (en) 2020-08-25
US10980874B2 (en) 2021-04-20
US9999665B2 (en) 2018-06-19
US20190111127A1 (en) 2019-04-18
US20200023058A1 (en) 2020-01-23
JP2020079245A (ja) 2020-05-28
US20170202952A1 (en) 2017-07-20
AU2020217310B2 (en) 2023-07-13
US20200376114A1 (en) 2020-12-03
CA2942166A1 (en) 2015-09-11
JP2021088590A (ja) 2021-06-10
WO2015134368A2 (en) 2015-09-11
CN106456805B (zh) 2020-01-10
WO2015134368A3 (en) 2015-11-26
EP3113801B1 (en) 2020-10-07
JP6652497B2 (ja) 2020-02-26
CN106456805A (zh) 2017-02-22
JP2017510262A (ja) 2017-04-13
AU2015225499B2 (en) 2020-05-14
JP7050193B2 (ja) 2022-04-07
JP6844045B2 (ja) 2021-03-17
AU2015225499A1 (en) 2016-10-20
US10076568B2 (en) 2018-09-18
CN110938604A (zh) 2020-03-31
US20160158343A1 (en) 2016-06-09
AU2020217310A1 (en) 2020-08-27

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