CN110934926A - 罗浮山百草油在制备治疗关节疼痛的药物中的应用 - Google Patents

罗浮山百草油在制备治疗关节疼痛的药物中的应用 Download PDF

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Publication number
CN110934926A
CN110934926A CN201911367565.2A CN201911367565A CN110934926A CN 110934926 A CN110934926 A CN 110934926A CN 201911367565 A CN201911367565 A CN 201911367565A CN 110934926 A CN110934926 A CN 110934926A
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parts
oil
herb
root
hundred
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叶耀良
黄炜忠
毛鑫
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Guangdong Luofushan Sinopharm Co Ltd
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Guangdong Luofushan Sinopharm Co Ltd
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    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
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Abstract

本发明公开了罗浮山百草油在制备治疗关节疼痛的药物中的应用，所述罗浮山百草油包含以下重量份的组分：樟脑20~40份、水杨酸甲酯200~300份、松节油80~110份、薄荷素油200~300份、丁香罗勒油10~20份、樟油100~200份、八角茴香油10~30份、肉桂油10~30份、冰片2~4份、薄荷脑20~35份、桉油30~50份、茶油提取物40~120份，罗浮山百草油中的各味药材之间互相配合，协同作用，起到祛风除湿、消肿止痛、清热解毒、活血、行气化瘀、祛风散寒的治疗作用，标本兼治，扶正祛邪，起效快，效果好，对治疗关节疼痛具有很好的临床疗效。

Description

罗浮山百草油在制备治疗关节疼痛的药物中的应用
技术领域
本发明涉及中药应用技术领域，尤其涉及罗浮山百草油在制备治疗关节疼痛的药物中的应用。
背景技术
关节疼痛主要是由于关节炎或关节病引起，导致关节痛、红肿、炎症和活动受阻、功能受限，随着老龄化时代的到来，关节疼痛的人群越来越庞大，且症状日趋普遍化和年轻化，目前市面上针对各种病因引起的关节疼痛，主要治疗方法包括西医的口服和注射疗法以及中医的以膏药贴剂为代表的一系列中药制剂等，中医疗法因其效果明显、使用方便且副作用小而越来越受到人们的欢迎，但传统的膏药贴，局限于递送脂溶性高、起效剂量小且药理作用强的药物，应用范围狭窄，作用效果比较缓慢，患者的依从性较差，影响治疗效果。
发明内容
针对现有技术的不足，本发明提供了罗浮山百草油在制备治疗关节疼痛的药物中的应用。
为了解决上述技术问题，本发明是通过以下技术方案进行实现的：
罗浮山百草油在制备治疗关节疼痛的药物中的应用，所述罗浮山百草油包含以下重量份的组分：樟脑20~40份、水杨酸甲酯200~300份、松节油80~110 份、薄荷素油200~300份、丁香罗勒油10~20份、樟油100~200 份、八角茴香油10~30份、肉桂油10~30份、冰片2~4份、薄荷脑20~35份、桉油30~50份、茶油提取物40~120份。
进一步的，所述罗浮山百草油包含以下重量份的组分：樟脑25~30份、水杨酸甲酯240~280份、松节油90~100份、薄荷素油220~300份、丁香罗勒油11~18份、樟油120~180份、八角茴香油14~20份、肉桂油15~25份、冰片2~3份、薄荷脑25~30份、桉油35~45份、茶油提取物60~100份。
进一步的，所述罗浮山百草油包含以下重量份的组分：樟脑25份、水杨酸甲酯240份、松节油90份、薄荷素油220份、丁香罗勒油11份、樟油120份、八角茴香油14份、肉桂油15份、冰片2份、薄荷脑25份、桉油35份、茶油提取物60份。
进一步的，所述罗浮山百草油包含以下重量份的组分：樟脑30份、水杨酸甲酯280份、松节油100份、薄荷素油300份、丁香罗勒油18份、樟油180份、八角茴香油20份、肉桂油25份、冰片3份、薄荷脑30份、桉油45份、茶油提取物100份。
进一步的，所述茶油提取物从茶油组合物中提取制得，所述茶油组合物包含以下重量份的组分：卷柏1.0份、鹅不食草1.0份、水芙蓉1.0份、辛夷1.0份、山白芷0.5份、徐长卿1.0份、山银花0.5 份、救必应0.5份、金不换1.0份、白半枫荷0.5份、荜澄茄0.5份、麻黄0.5份、重楼0.25份、人字草0.25份、金线风0.25份、金耳环0.25份、一朵云0.25份、吊黄0.25份。
进一步的，所述茶油组合物还包括以下重量份的组分：两面针1.0份、九里香1.0份、红花1.0份、水芙蓉1.0份、千里光1.0份、大头陈1.0份、当归1.0份、三七1.0份、肿节风1.0 份、鸡骨香1.0份、砂仁0.55份、独活0.55份、羌活0.55份、姜皮0.55份、陈皮0.55份、香附0.5 份、野菊花0.5份、桂枝0.5份、小罗伞0.5份、蔓荆子0.5份、桔梗0.5份、紫珠叶0.5份、地胆草 0.5份、细辛0.5份、五指柑0.5份、肉豆蔻0.5份、木防己0.5份、三叉苦0.5份、地稔0.5份、防风0.5份、半枝莲0.5份、铁包金0.5份、柴胡0.5份、飞天蠄蟧0.5份、鸡骨草0.5 份、荆芥0.5份、虎杖0.5份、钩藤0.5份、一枝黄花0.45份、白花灯笼0.43份、白花蛇舌草0.43份、石仙桃0.25份、五月艾0.25份、皂角刺0.25份、木香0.25份、山芝麻0.25份、益母草0.25份、紫苏叶0.25份、倒扣草0.25份、侧柏叶0.25份、鱼腥草0.25份。
进一步的，所述茶油提取物是将茶油组合物粉碎成粗粉，混匀后加入茶油，浸渍10~30天，过滤，即得所述茶油提取物。
进一步的，所述茶油提取物是将茶油组合物粉碎成粗粉，混匀后加入2~4倍体积的茶油，在40~60℃浸渍10~30天，趁热过滤，滤液静置冷却至室温，即得所述茶油提取物。
进一步的，所述治疗关节疼痛的药物为外用制剂。
进一步的，所述外用制剂为外用搽剂。
进一步的，所述外用搽剂的用法为涂搽患处，每日2~3次。
本发明的罗浮山百草油的用量用法：外用，涂搽患处，让药液均匀覆盖于患处区域，每日2~3次即可。
相对于现有技术，本发明的有益效果为：
本发明将罗浮山百草油应用于制备治疗关节疼痛的药物，从病发本质机理出发，成分为中药配方，通过采用樟脑、水杨酸甲酯、松节油、薄荷素油、丁香罗勒油、樟油、八角茴香油、肉桂油、冰片、薄荷脑、桉油、茶油提取物等原料并进行适合的重量配比，罗浮山百草油中的各味药材之间互相配合，协同作用，起到祛风除湿、消肿止痛、清热解毒、活血、行气化瘀、祛风散寒的治疗作用，标本兼治，扶正祛邪，对各类骨骼关节疼痛，起效快，效果好，且外用涂抹无皮肤刺激性，在关节疼痛处皮肤形成较高药物浓度，高效透皮吸收，药物起效快，避免口服药物经过肝脏的首过效应；治愈后不易复发，疗效确切，安全性高，使用便捷，无成瘾性、耐药性和依赖性，无胃肠道、肝肾损伤副作用，市场应用前景广泛。
典型案例：李某，年龄55岁，患者患关节疼痛疾病，多年来一直抬不起腿，一抬腿时候会感到麻和痛的感觉，试过外用贴膏、口服药物、外用软膏治疗，但未奏效；用本发明的罗浮山百草油治疗：将罗浮山百草油涂抹于疼痛部位，每日3次，使用5天后，可以轻微向上抬腿，行走时麻和痛的感觉减弱；继续使用15天后，能够顺利抬腿且麻和疼痛肿胀症状完全消失，能正常行动，6个月无复发。
具体实施方式
为了便于本领域的技术人员理解，下面结合具体实施例对本发明作进一步说明，实施方式提及的内容并不限定本发明的范围。
实施例1
本实施例提供了罗浮山百草油在制备治疗关节疼痛的药物中的应用，所述治疗关节疼痛的药物为外用搽剂，其中，罗浮山百草油包含以下重量份的组分：樟脑25份、水杨酸甲酯240份、松节油90份、薄荷素油220份、丁香罗勒油11份、樟油120份、八角茴香油14份、肉桂油15份、冰片2份、薄荷脑25份、桉油35份、茶油提取物60份。
而茶油提取物从茶油组合物中提取制得，具体的，是将茶油组合物粉碎成粗粉，过30目筛，混匀后加入2倍体积的茶油，于45℃浸渍25天，趁热过滤，滤液静置冷却至室温，得到茶油提取物。
所述茶油组合物包含以下重量份的组分：卷柏1.0份、鹅不食草1.0份、水芙蓉1.0份、辛夷1.0份、山白芷0.5份、徐长卿1.0份、山银花0.5 份、救必应0.5份、金不换1.0份、白半枫荷0.5份、荜澄茄0.5份、麻黄0.5份、重楼0.25份、人字草0.25份、金线风0.25份、金耳环0.25份、一朵云0.25份、吊黄0.25份、两面针1.0份、九里香1.0份、红花1.0份、水芙蓉1.0份、千里光1.0份、大头陈1.0份、当归1.0份、三七1.0份、肿节风1.0 份、鸡骨香1.0份、砂仁0.55份、独活0.55份、羌活0.55份、姜皮0.55份、陈皮0.55份、香附0.5 份、野菊花0.5份、桂枝0.5份、小罗伞0.5份、蔓荆子0.5份、桔梗0.5份、紫珠叶0.5份、地胆草 0.5份、细辛0.5份、五指柑0.5份、肉豆蔻0.5份、木防己0.5份、三叉苦0.5份、地稔0.5份、防风0.5份、半枝莲0.5份、铁包金0.5份、柴胡0.5份、飞天蠄蟧0.5份、鸡骨草0.5 份、荆芥0.5份、虎杖0.5份、钩藤0.5份、一枝黄花0.45份、白花灯笼0.43份、白花蛇舌草0.43 份、石仙桃0.25份、五月艾0.25份、皂角刺0.25份、木香0.25份、山芝麻0.25份、益母草0.25 份、紫苏叶0.25份、倒扣草0.25份、侧柏叶0.25份、鱼腥草0.25份。
本实施例的治疗关节疼痛的药物为外用搽剂，制备方法包括如下步骤：
将茶油提取物与其他各组分混合搅拌均匀，静置5天，取澄清液，加2倍体积的茶油稀释即得。
实施例2
本实施例提供了罗浮山百草油在制备治疗关节疼痛的药物中的应用，所述治疗关节疼痛的药物为外用搽剂，其中，罗浮山百草油包含以下重量份的组分：樟脑30份、水杨酸甲酯280份、松节油100份、薄荷素油300份、丁香罗勒油18份、樟油180份、八角茴香油20份、肉桂油25份、冰片3份、薄荷脑30份、桉油45份、茶油提取物100份。
而茶油提取物从茶油组合物中提取制得，具体的，是将茶油组合物粉碎成粗粉，过30目筛，混匀后加入3倍体积的茶油，于60℃浸渍10天，趁热过滤，滤液静置冷却至室温，得到茶油提取物。
所述茶油组合物包含以下重量份的组分：卷柏1.0份、鹅不食草1.0份、水芙蓉1.0份、辛夷1.0份、山白芷0.5份、徐长卿1.0份、山银花0.5 份、救必应0.5份、金不换1.0份、白半枫荷0.5份、荜澄茄0.5份、麻黄0.5份、重楼0.25份、人字草0.25份、金线风0.25份、金耳环0.25份、一朵云0.25份、吊黄0.25份、两面针1.0份、九里香1.0份、红花1.0份、水芙蓉1.0份、千里光1.0份、大头陈1.0份、当归1.0份、三七1.0份、肿节风1.0 份、鸡骨香1.0份、砂仁0.55份、独活0.55份、羌活0.55份、姜皮0.55份、陈皮0.55份、香附0.5 份、野菊花0.5份、桂枝0.5份、小罗伞0.5份、蔓荆子0.5份、桔梗0.5份、紫珠叶0.5份、地胆草 0.5份、细辛0.5份、五指柑0.5份、肉豆蔻0.5份、木防己0.5份、三叉苦0.5份、地稔0.5份、防风0.5份、半枝莲0.5份、铁包金0.5份、柴胡0.5份、飞天蠄蟧0.5份、鸡骨草0.5 份、荆芥0.5份、虎杖0.5份、钩藤0.5份、一枝黄花0.45份、白花灯笼0.43份、白花蛇舌草0.43 份、石仙桃0.25份、五月艾0.25份、皂角刺0.25份、木香0.25份、山芝麻0.25份、益母草0.25 份、紫苏叶0.25份、倒扣草0.25份、侧柏叶0.25份、鱼腥草0.25份。
本实施例的治疗关节疼痛的药物为外用搽剂，制备方法包括如下步骤：
将茶油提取物与其他各组分混合搅拌均匀，静置5天，取澄清液，加2倍体积的茶油稀释即得。
实施例3
本实施例提供了罗浮山百草油在制备治疗关节疼痛的药物中的应用，所述治疗关节疼痛的药物为外用搽剂，其中，罗浮山百草油包含以下重量份的组分：樟脑20份、水杨酸甲酯200份、松节油80份、薄荷素油200份、丁香罗勒油10份、樟油100份、八角茴香油10份、肉桂油10份、冰片2份、薄荷脑20份、桉油30份、茶油提取物40份。
而茶油提取物从茶油组合物中提取制得，具体的，是将茶油组合物粉碎成粗粉，过30目筛，混匀后加入2倍体积的茶油，于50℃浸渍15天，趁热过滤，滤液静置冷却至室温，得到茶油提取物。
所述茶油组合物包含以下重量份的组分：卷柏1.0份、鹅不食草1.0份、水芙蓉1.0份、辛夷1.0份、山白芷0.5份、徐长卿1.0份、山银花0.5 份、救必应0.5份、金不换1.0份、白半枫荷0.5份、荜澄茄0.5份、麻黄0.5份、重楼0.25份、人字草0.25份、金线风0.25份、金耳环0.25份、一朵云0.25份、吊黄0.25份、两面针1.0份、九里香1.0份、红花1.0份、水芙蓉1.0份、千里光1.0份、大头陈1.0份、当归1.0份、三七1.0份、肿节风1.0 份、鸡骨香1.0份、砂仁0.55份、独活0.55份、羌活0.55份、姜皮0.55份、陈皮0.55份、香附0.5 份、野菊花0.5份、桂枝0.5份、小罗伞0.5份、蔓荆子0.5份、桔梗0.5份、紫珠叶0.5份、地胆草 0.5份、细辛0.5份、五指柑0.5份、肉豆蔻0.5份、木防己0.5份、三叉苦0.5份、地稔0.5份、防风0.5份、半枝莲0.5份、铁包金0.5份、柴胡0.5份、飞天蠄蟧0.5份、鸡骨草0.5 份、荆芥0.5份、虎杖0.5份、钩藤0.5份、一枝黄花0.45份、白花灯笼0.43份、白花蛇舌草0.43 份、石仙桃0.25份、五月艾0.25份、皂角刺0.25份、木香0.25份、山芝麻0.25份、益母草0.25 份、紫苏叶0.25份、倒扣草0.25份、侧柏叶0.25份、鱼腥草0.25份。
本实施例的治疗关节疼痛的药物为外用搽剂，制备方法包括如下步骤：
将茶油提取物与其他各组分混合搅拌均匀，静置5天，取澄清液，加2倍体积的茶油稀释即得。
实施例4
本实施例提供了罗浮山百草油在制备治疗关节疼痛的药物中的应用，所述治疗关节疼痛的药物为外用搽剂，其中，罗浮山百草油包含以下重量份的组分：樟脑40份、水杨酸甲酯300份、松节油110份、薄荷素油300份、丁香罗勒油20份、樟油200份、八角茴香油30份、肉桂油30份、冰片4份、薄荷脑35份、桉油50份、茶油提取物120份。
而茶油提取物从茶油组合物中提取制得，具体的，是将茶油组合物粉碎成粗粉，过30目筛，混匀后加入4倍体积的茶油，于55℃浸渍14天，趁热过滤，滤液静置冷却至室温，得到茶油提取物。
所述茶油组合物包含以下重量份的组分：卷柏1.0份、鹅不食草1.0份、水芙蓉1.0份、辛夷1.0份、山白芷0.5份、徐长卿1.0份、山银花0.5 份、救必应0.5份、金不换1.0份、白半枫荷0.5份、荜澄茄0.5份、麻黄0.5份、重楼0.25份、人字草0.25份、金线风0.25份、金耳环0.25份、一朵云0.25份、吊黄0.25份、两面针1.0份、九里香1.0份、红花1.0份、水芙蓉1.0份、千里光1.0份、大头陈1.0份、当归1.0份、三七1.0份、肿节风1.0 份、鸡骨香1.0份、砂仁0.55份、独活0.55份、羌活0.55份、姜皮0.55份、陈皮0.55份、香附0.5 份、野菊花0.5份、桂枝0.5份、小罗伞0.5份、蔓荆子0.5份、桔梗0.5份、紫珠叶0.5份、地胆草 0.5份、细辛0.5份、五指柑0.5份、肉豆蔻0.5份、木防己0.5份、三叉苦0.5份、地稔0.5份、防风0.5份、半枝莲0.5份、铁包金0.5份、柴胡0.5份、飞天蠄蟧0.5份、鸡骨草0.5 份、荆芥0.5份、虎杖0.5份、钩藤0.5份、一枝黄花0.45份、白花灯笼0.43份、白花蛇舌草0.43 份、石仙桃0.25份、五月艾0.25份、皂角刺0.25份、木香0.25份、山芝麻0.25份、益母草0.25 份、紫苏叶0.25份、倒扣草0.25份、侧柏叶0.25份、鱼腥草0.25份。
本实施例的治疗关节疼痛的药物为外用搽剂，制备方法包括如下步骤：
将茶油提取物与其他各组分混合搅拌均匀，静置5天，取澄清液，加2倍体积的茶油稀释即得。
实施例5
本实施例提供了罗浮山百草油在制备治疗关节疼痛的药物中的应用，所述治疗关节疼痛的药物为外用搽剂，其中，罗浮山百草油包含以下重量份的组分：樟脑28份、水杨酸甲酯250份、松节油95份、薄荷素油250份、丁香罗勒油15份、樟油160份、八角茴香油25份、肉桂油25份、冰片3份、薄荷脑30份、桉油45份、茶油提取物110份。
而茶油提取物从茶油组合物中提取制得，具体的，是将茶油组合物粉碎成粗粉，过30目筛，混匀后加入3倍体积的茶油，于55℃浸渍14天，趁热过滤，滤液静置冷却至室温，得到茶油提取物。
所述茶油组合物包含以下重量份的组分：卷柏1.0份、鹅不食草1.0份、水芙蓉1.0份、辛夷1.0份、山白芷0.5份、徐长卿1.0份、山银花0.5 份、救必应0.5份、金不换1.0份、白半枫荷0.5份、荜澄茄0.5份、麻黄0.5份、重楼0.25份、人字草0.25份、金线风0.25份、金耳环0.25份、一朵云0.25份、吊黄0.25份、两面针1.0份、九里香1.0份、红花1.0份、水芙蓉1.0份、千里光1.0份、大头陈1.0份、当归1.0份、三七1.0份、肿节风1.0 份、鸡骨香1.0份、砂仁0.55份、独活0.55份、羌活0.55份、姜皮0.55份、陈皮0.55份、香附0.5 份、野菊花0.5份、桂枝0.5份、小罗伞0.5份、蔓荆子0.5份、桔梗0.5份、紫珠叶0.5份、地胆草 0.5份、细辛0.5份、五指柑0.5份、肉豆蔻0.5份、木防己0.5份、三叉苦0.5份、地稔0.5份、防风0.5份、半枝莲0.5份、铁包金0.5份、柴胡0.5份、飞天蠄蟧0.5份、鸡骨草0.5 份、荆芥0.5份、虎杖0.5份、钩藤0.5份、一枝黄花0.45份、白花灯笼0.43份、白花蛇舌草0.43 份、石仙桃0.25份、五月艾0.25份、皂角刺0.25份、木香0.25份、山芝麻0.25份、益母草0.25 份、紫苏叶0.25份、倒扣草0.25份、侧柏叶0.25份、鱼腥草0.25份。
本实施例的治疗关节疼痛的药物为外用搽剂，制备方法包括如下步骤：
将茶油提取物与其他各组分混合搅拌均匀，静置5天，取澄清液，加2倍体积的茶油稀释即得。
实施例6 对罗浮山百草油进行小鼠热板致痛试验
研究实验试剂：实施例1中所述的外用搽剂；阿司匹林；茶油。
药物剂量：小鼠高剂量组使用本实施例1所述的中药组合物0.2ml；中剂量组使用本实施例1所述的中药组合物0.1ml、用茶油配至0.2ml；低剂量组使用本实施例1所述的中药组合物0.05ml、用茶油配至0.2ml；阿司匹林组0.1ml；空白组使用茶油0.2ml。
取ICR小鼠75只，体重20~24g，雌雄兼用，随机分为空白组，本发明中所述的中药组合物高、中、低剂量组和阿司匹林组共5组，每组15只，采用小鼠热板致痛法，本实施例1所述的中药组合物高、中、低剂量组的给药方式为涂抹，给药剂量如下，阿司匹林组采用灌胃给药方式，空白组的给药方式为涂抹，每天两次，连续六天。于末次给药1h后，进行小鼠热板法试验，数据见下表。
Figure DEST_PATH_IMAGE001
与空白组比较：*表示P<0.05，**表示P<0.01。
结果：与空白组比较，实施例1中罗浮山百草油各剂量组和阿司匹林组均可延长热板所致小鼠出现痛的反应时间，即罗浮山百草油对小鼠热板致痛有显著的镇痛作用，在实验所用剂量范围内，本发明的罗浮山百草油的镇痛效果随剂量的加大而增强。
实施例7 罗浮山百草油用于治疗关节疼痛的临床治疗效果
为证实本发明的罗浮山百草油具有治疗关节疼痛的疗效，用按实施例2制得的搽剂，进行了以下试验研究：
病例选择：收治门诊患者200例膝关节疼痛患者，男101例，女99例，年龄30~65岁，将200例患者随机分成两组，每组100例，分别为治疗组和对照组，其中各组在年龄、性别、病情等上统计学处理无显著性差异（P＞0.05），有可比性。
诊断标准：膝关节红肿、灼热，关节活动时出现疼痛、肿胀症状。
治疗方法：
治疗组：将罗浮山百草油涂抹于疼痛部位，让药液均匀覆盖于患处区域，按摩5～10分钟至患处发热，每日3次，连续治疗15天；
对照组：采用麝香祛痛搽剂（李时珍医药集团有限公司，国药准字Z42021326），涂搽患处，按摩5～10分钟至患处发热，每日3次，连续治疗15天；
疗效标准：
1、治愈-患者经治疗后膝关节疼痛及肿胀等症状消失，关节功能及活动恢复正常；
2、显效-治疗后患者膝关节疼痛及肿胀基本消失，关节活动基本正常, 过度活动出现轻微疼痛；
3、好转-治疗后患者膝关节疼痛及肿胀均缓解，关节活动基本正常；
4、无效-患者膝关节肿胀及疼痛等症状无改善，功能未见恢复。
治疗结果统计：总有效率=治愈率+好转率。
Figure 289288DEST_PATH_IMAGE002
如表2所示，通过对比治愈率和总有效率，可以发现治疗组明显高于对照组，经过本发明的罗浮山百草油治疗关节疼痛后，患者临床症状及体征显著改善，上述结果也进一步表明，本发明的罗浮山百草油在治疗关节疼痛上相对于采用麝香祛痛搽剂在治疗关节疼痛效果显著，安全性高，疗效好；具有良好的临床效果，能有效提高治疗的治愈率，具有现有同类产品不具备的功效；临床使用时，罗浮山百草油中的各味药材之间互相配合，协同作用，共同起到清热解毒、活血、止痛、行气化瘀、祛风散寒的作用，标本兼治，扶正祛邪，治愈各类骨骼关节疼痛，无不良反应和任何毒副作用，具有广阔的市场应用前景。
以上所述实施例仅表达了本发明的实施方式，其描述较为具体和详细，但并不能因此而理解为对本发明专利范围的限制，但凡采用等同替换或等效变换的形式所获得的技术方案，均应落在本发明的保护范围之内。

Claims (10)

1. 罗浮山百草油在制备治疗关节疼痛的药物中的应用，其特征在于，所述罗浮山百草油包含以下重量份的组分：樟脑20~40份、水杨酸甲酯200~300份、松节油80~110 份、薄荷素油200~300份、丁香罗勒油10~20份、樟油100~200 份、八角茴香油10~30份、肉桂油10~30份、冰片2~4份、薄荷脑20~35份、桉油30~50份、茶油提取物40~120份。
2.根据权利要求1所述的罗浮山百草油在制备治疗关节疼痛的药物中的应用，其特征在于，所述罗浮山百草油包含以下重量份的组分：樟脑25~30份、水杨酸甲酯240~280份、松节油90~100份、薄荷素油220~300份、丁香罗勒油11~18份、樟油120~180份、八角茴香油14~20份、肉桂油15~25份、冰片2~3份、薄荷脑25~30份、桉油35~45份、茶油提取物60~100份。
3.根据权利要求1所述的罗浮山百草油在制备治疗关节疼痛的药物中的应用，其特征在于，所述罗浮山百草油包含以下重量份的组分：樟脑25份、水杨酸甲酯240份、松节油90份、薄荷素油220份、丁香罗勒油11份、樟油120份、八角茴香油14份、肉桂油15份、冰片2份、薄荷脑25份、桉油35份、茶油提取物60份。
4.根据权利要求1所述的罗浮山百草油在制备治疗关节疼痛的药物中的应用，其特征在于，所述罗浮山百草油包含以下重量份的组分：樟脑30份、水杨酸甲酯280份、松节油100份、薄荷素油300份、丁香罗勒油18份、樟油180份、八角茴香油20份、肉桂油25份、冰片3份、薄荷脑30份、桉油45份、茶油提取物100份。
5. 根据权利要求1所述的罗浮山百草油在制备治疗关节疼痛的药物中的应用，其特征在于，所述茶油提取物从茶油组合物中提取制得，所述茶油组合物包含以下重量份的组分：卷柏1.0份、鹅不食草1.0份、水芙蓉1.0份、辛夷1.0份、山白芷0.5份、徐长卿1.0份、山银花0.5 份、救必应0.5份、金不换1.0份、白半枫荷0.5份、荜澄茄0.5份、麻黄0.5份、重楼0.25份、人字草0.25份、金线风0.25份、金耳环0.25份、一朵云0.25份、吊黄0.25份。
6. 根据权利要求5所述的罗浮山百草油在制备治疗关节疼痛的药物中的应用，其特征在于，所述茶油组合物还包括以下重量份的组分：两面针1.0份、九里香1.0份、红花1.0份、水芙蓉1.0份、千里光1.0份、大头陈1.0份、当归1.0份、三七1.0份、肿节风1.0 份、鸡骨香1.0份、砂仁0.55份、独活0.55份、羌活0.55份、姜皮0.55份、陈皮0.55份、香附0.5 份、野菊花0.5份、桂枝0.5份、小罗伞0.5份、蔓荆子0.5份、桔梗0.5份、紫珠叶0.5份、地胆草 0.5份、细辛0.5份、五指柑0.5份、肉豆蔻0.5份、木防己0.5份、三叉苦0.5份、地稔0.5份、防风0.5份、半枝莲0.5份、铁包金0.5份、柴胡0.5份、飞天蠄蟧0.5份、鸡骨草0.5 份、荆芥0.5份、虎杖0.5份、钩藤0.5份、一枝黄花0.45份、白花灯笼0.43份、白花蛇舌草0.43 份、石仙桃0.25份、五月艾0.25份、皂角刺0.25份、木香0.25份、山芝麻0.25份、益母草0.25 份、紫苏叶0.25份、倒扣草0.25份、侧柏叶0.25份、鱼腥草0.25份。
7.根据权利要求1所述的罗浮山百草油在制备治疗关节疼痛的药物中的应用，其特征在于，所述茶油提取物是将茶油组合物粉碎成粗粉，混匀后加入茶油，浸渍10~30天，过滤，即得所述茶油提取物。
8.根据权利要求1所述的罗浮山百草油在制备治疗关节疼痛的药物中的应用，其特征在于，所述治疗关节疼痛的药物为外用制剂。
9.根据权利要求8所述的罗浮山百草油在制备治疗关节疼痛的药物中的应用，其特征在于，所述外用制剂为外用搽剂。
10.根据权利要求9所述的罗浮山百草油在制备治疗关节疼痛的药物中的应用，其特征在于，所述外用搽剂的用法为涂搽患处，每日2~3次。
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