CN110895220B - Pathological specimen embedding device - Google Patents
Pathological specimen embedding device Download PDFInfo
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- CN110895220B CN110895220B CN202010064435.8A CN202010064435A CN110895220B CN 110895220 B CN110895220 B CN 110895220B CN 202010064435 A CN202010064435 A CN 202010064435A CN 110895220 B CN110895220 B CN 110895220B
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- flat plate
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- 230000001575 pathological effect Effects 0.000 title claims abstract description 18
- 239000007788 liquid Substances 0.000 claims abstract description 28
- 238000003860 storage Methods 0.000 claims description 20
- 238000005192 partition Methods 0.000 claims description 13
- 238000010438 heat treatment Methods 0.000 claims description 5
- 230000006835 compression Effects 0.000 claims description 3
- 238000007906 compression Methods 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 238000005485 electric heating Methods 0.000 description 7
- 238000012326 endoscopic mucosal resection Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000004575 stone Substances 0.000 description 2
- 208000005156 Dehydration Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 238000012143 endoscopic resection Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000012335 pathological evaluation Methods 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 210000004876 tela submucosa Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000004018 waxing Methods 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention relates to a pathological specimen embedding device, which effectively solves the problems that the prior manual embedding of specimen strips wastes time and labor and has poor effect; the technical scheme includes that the device comprises a leveling device and a clamping device, wherein the leveling device is composed of a plurality of communicated piston cylinders, liquid levels in the piston cylinders are automatically leveled during leveling and then are locked to be used as a horizontal reference, the clamping device comprises two vertical telescopic rods which are symmetrically arranged left and right, a clamp is mounted at the upper end of each telescopic rod, and the clamp can move downwards along with the telescopic rods; the invention can simply and quickly realize high-quality embedding of the specimen strip, effectively improve the embedding efficiency and quality and reduce the work burden of medical personnel.
Description
Technical Field
The invention relates to the field of pathological specimen manufacturing, in particular to a pathological specimen embedding device.
Background
Endoscopic Submucosa Dissection (ESD)/Endoscopic Mucosal Resection (EMR) is the first method for treating early cancers of the digestive tract, and postoperative pathological evaluation of endoscopic resection specimens plays a very important guiding role in clinically making a next treatment scheme; the preparation of pathological specimens sequentially requires the following steps: washing a specimen, flattening and fixing the specimen, cutting the specimen, dehydrating the specimen, waxing the specimen and slicing.
In the above steps, the specimen is cut into strips, and then the strips are embedded in the wax block after dehydration treatment, and when embedding, the strips are required to be straight and not twisted, two ends of the strips are positioned in the same horizontal plane and not inclined, and when embedding a plurality of strips, a plurality of strips are required to be positioned in the same plane; medical personnel heats tweezers with the alcohol burner when embedding sample strip at present, then centre gripping sample strip melts the wax stone and buries the sample strip into the wax stone, by the meticulous adjustment of carrying out the sample strip of medical personnel, makes it be close above-mentioned ideal state as far as possible, this is an extremely harsh and hard work, and embedding speed is slow, and the embedding effect is uneven moreover.
Disclosure of Invention
Aiming at the situation, the invention provides a pathological specimen embedding device for overcoming the defects of the prior art, and effectively solves the problems that the conventional manual specimen embedding strip is time-consuming and labor-consuming and has poor effect.
The pathological specimen embedding device comprises a base consisting of supporting legs and a horizontal first flat plate, wherein the upper surface of the first flat plate is provided with a plurality of piston cylinders which are uniformly distributed on the circumference and a liquid storage bottle, the bottom of each piston cylinder is communicated with the bottom of the liquid storage bottle through a pipeline, a partition plate which can move up and down is arranged in the liquid storage bottle, the side wall of the partition plate is attached to the inner wall of the liquid storage bottle, and the partition plate moves upwards to seal pipe openings of the pipelines on the side wall of the liquid storage bottle; a piston is arranged in each piston cylinder, a vertical rod is fixed at the upper end of each piston, a horizontal second flat plate is arranged above the first flat plate and is borne by a plurality of vertical rods, a horizontal third flat plate capable of moving up and down is arranged below the first flat plate, a plurality of vertical plungers corresponding to the piston cylinders one by one are uniformly distributed on the circumference of the third flat plate, the upper end of each plunger penetrates through the first flat plate and extends into the corresponding piston cylinder, and the third flat plate can move upwards to drive the plungers to move upwards synchronously; the upper surface of the second flat plate is provided with two vertical telescopic rods which are symmetrically arranged left and right, the upper end of each telescopic rod is provided with a clamp, and the clamps can move downwards along with the telescopic rods.
The invention can simply and quickly realize high-quality embedding of the specimen strip, effectively improve the embedding efficiency and quality and reduce the work burden of medical personnel.
Drawings
Fig. 1 is a front sectional view of the present invention.
FIG. 2 is a front cross-sectional view of the base of the present invention shown tilted and un-leveled.
Fig. 3 is a front cross-sectional view of the base of the present invention tilted and leveled.
Fig. 4 is a right side cross-sectional view of the present invention.
Fig. 5 is an enlarged view of the position a in fig. 1.
Fig. 6 is an enlarged view of the position B in fig. 1.
Fig. 7 is an enlarged view of the position C in fig. 2.
Fig. 8 is an enlarged view of the position D in fig. 3.
Fig. 9 is an enlarged view of the position E in fig. 4.
Detailed Description
The following description of the embodiments of the present invention will be made in detail with reference to the accompanying drawings.
As shown in the figures 1 to 9, the invention comprises a base composed of supporting legs 1 and a horizontal first flat plate 2, wherein the upper surface of the first flat plate 2 is provided with a plurality of piston cylinders 3 which are uniformly distributed on the circumference and a liquid storage bottle 4, the bottom of each piston cylinder 3 is communicated with the bottom of the liquid storage bottle 4 through a pipeline 5, a partition plate 6 which can move up and down is arranged in the liquid storage bottle 4, the side wall of the partition plate 6 is attached to the inner wall of the liquid storage bottle 4, and the partition plate 6 moves upwards to seal the pipe orifices of the pipelines 5 on the side wall of the liquid storage bottle 4; a piston 7 is arranged in each piston cylinder 3, a vertical rod 8 is fixed at the upper end of each piston 7, a horizontal second flat plate 9 is arranged above the first flat plate 2, the second flat plate 9 is borne by a plurality of vertical rods 8, a horizontal third flat plate 10 capable of moving up and down is arranged below the first flat plate 2, a plurality of vertical plungers 11 which are in one-to-one correspondence with the piston cylinders 3 are uniformly distributed on the circumference of the third flat plate 10, the upper end of each plunger 11 penetrates through the first flat plate 2 and extends into the corresponding piston cylinder 3, and the third flat plate 10 can move upwards to drive the plungers 11 to move upwards synchronously; the upper surface of the second plate 9 is provided with two vertical telescopic rods which are symmetrically arranged left and right, the upper end of each telescopic rod is provided with a clamp 12, and the clamps 12 can move downwards along with the telescopic rods.
A vertical first bolt 13 penetrates through the third flat plate 10, the upper end of the first bolt 13 is in threaded fit with the first flat plate 2, and the third flat plate 10 can be driven to move upwards by rotating the first bolt 13, so that the plungers 11 are pushed to move upwards synchronously.
The lower surface of the second flat plate 9 is fixed with a plurality of vertical first guide rods 14, the first flat plate 2 is provided with a plurality of vertical first guide holes 15 corresponding to the first guide rods 14 one by one, the lower end of each first guide rod 14 penetrates into the corresponding first guide hole 15, and the diameter of each first guide hole 15 is larger than that of each first guide rod 14, so that the first flat plate 2 cannot slide off and has a certain movement allowance.
A plurality of first tension springs 16 which are uniformly distributed on the circumference are connected between the first flat plate 2 and the second flat plate 9, so that the lower surface of the second flat plate 9 is in effective contact with the upper ends of a plurality of vertical rods 8.
Each piston 7 is provided with a vertical air release hole 17, the lower surface of the piston 7 is hung with a horizontal floating plate 19 through a pull rope 18, and the floating plate 19 moves upwards to seal the air release hole 17; the air release hole 17 can discharge air in the piston cylinder 3, so that water can smoothly enter the piston cylinder 3, and the floating plate 19 can close the air release hole 17 when the plunger 11 pushes the piston 7 upwards through a water column.
The telescopic rod is formed by coaxially sleeving an inner rod 20 and an outer rod 21, the lower end of the outer rod 21 is fixed on the second flat plate 9, a pressure spring 22 is installed between the upper end of the inner rod 20 and the upper end of the outer rod 21, and the inner rods 20 of the two compression rods can be compressed downwards at the same height, so that the two clamps 12 are located at the same height.
The upper end of each inner rod 20 is fixed with a horizontal screw 23, each screw 23 is sleeved with a sliding sleeve 24, the two clamps 12 are fixed on the two sliding sleeves 24 in a one-to-one correspondence mode and face downwards, each screw 23 is screwed with a first nut 25, the sliding sleeves 24 are located between the first nuts 25 and the inner rods 20, the positions of the sliding sleeves 24 on the screws 23 can be adjusted by screwing the first nuts 25, and therefore the distance between the two clamps 12 is adjusted to be equal to the length of a specimen strip.
Each screw 23 is screwed with a second nut 26 positioned between the sliding sleeve 24 and the inner rod 20, each second nut 26 is fixed with a fixing rod 27 which faces downwards vertically, a horizontal electric heating wire 28 is connected between the lower ends of the two fixing rods 27, and the electric heating wire 28 is lower than the clamp 12; the heating wire 28 can enter the wax block before the sample strip, melt the wax block, so that the sample strip can be embedded in the wax block, and after the embedding is completed, the two second nuts 26 are slightly rotated to remove the heating wire 28 from the lower part of the sample strip to the front side or the rear side, and then the clamp 12 is released, so that the clamp 12 and the heating wire 28 can be lifted out of the wax block.
A horizontal fourth flat plate 29 is arranged above the second flat plate 9, a second tension spring 30 is connected between the second flat plate 9 and the fourth flat plate 29, a plurality of vertical second guide rods 31 are fixed on the lower surface of the fourth flat plate 29, the second guide rods 31 penetrate through the second flat plate 9, a vertical second bolt 32 is screwed on the second flat plate 9, the upper end of the second bolt 32 abuts against the lower surface of the fourth flat plate 29, the height of the fourth flat plate 29 can be adjusted by screwing the second bolt 32, and the fourth flat plate 29 cannot be horizontally displaced by the second guide rods 31.
The top of stock solution bottle 4 be equipped with a vertical third bolt 33 soon, the lower extreme and the baffle 6 of third bolt 33 rotate to be connected, can drive baffle 6 through third bolt 33 and reciprocate.
According to the invention, water is filled in the liquid storage bottle 4, when the device is used, the device is firstly placed on a workbench, then the third bolt 33 is rotated to enable the partition plate 6 to move downwards, pipe orifices of the plurality of pipelines 5 on the side wall of the liquid storage bottle 4 are opened, water in the liquid storage bottle 4 can flow into the plurality of piston cylinders 3 through the pipelines 5, as the plurality of piston cylinders 3 are communicated with each other through the pipelines 5 and the liquid storage bottle 4, the liquid levels in the cavities of the plurality of pistons 7 are the same, when liquid columns with certain heights are formed in the plurality of piston cylinders 3, the third bolt 33 is rotated to drive the partition plate 6 to move upwards to seal the plurality of pipelines 5, and the plurality of piston cylinders 3 are isolated from each; the liquid level in each piston cylinder 3 is not contacted with the piston 7, and in the process, air in the piston cylinder 3 can be discharged through the air leakage hole 17 on the piston 7, so that water can enter the piston cylinder 3 without resistance.
After the piston cylinders 3 are disconnected, the first bolts 13 are screwed to pull the third flat plate 10 to move upwards, so that the plungers 11 are pushed to move upwards synchronously, the plungers 11 move upwards to push water columns in the piston cylinders 3 to move upwards synchronously until the liquid columns are all contacted with the bottom of the piston 7 and push the piston 7 to move upwards for a certain distance, and after the water surface is contacted with the floating plate 19, the floating plate 19 is pressed to the piston 7 so that the air leakage holes 17 are closed, so that water is prevented from leaking from the air leakage holes 17; because the liquid level height in each piston cylinder 3 is the same and the plunger 11 moves upward for the same distance, the liquid column finally pushes the pistons 7 to the equal-height position, so that the upper ends of the vertical rods 8 are equal in height, and the second flat plate 9 and the fourth flat plate 29 are in the horizontal position no matter whether the base is horizontal or not, so that a horizontal bearing platform is provided for the wax block, namely a constant reference is provided for the embedding surface of the standard strip, and meanwhile, the wax block can be prevented from flowing to form an inclined plane or wax beads after being melted.
After the second flat plate 9 and the fourth flat plate 29 are adjusted to be horizontal, a wax block is placed on the fourth flat plate 29, then two ends of a sample strip are respectively clamped on the clamps 12 at the two ends, then the first nuts 25 are screwed to adjust the distance between the sliding sleeves 24 to straighten the sample strip, then the electric heating wires 28 are electrified, the inner rods 20 of the two telescopic rods are simultaneously pressed downwards by two hands, the electric heating wires 28 and the sample strip extend downwards into the wax block, the electric heating wires 28 enter the wax block in front of the sample strip to melt the wax block, so that the sample strip can be embedded into the wax block, after the sample strip is embedded in place, the two second nuts 26 are slightly rotated to remove the electric heating wires 28 from the lower part of the sample strip to the front side or the rear side, then the clamps 12 are loosened, the clamps 12 and the electric heating wires 28 can be lifted out of the wax block, and then new sample strips are clamped to be embedded.
Because the distance that the two inner rods 20 can be pressed down is the same, the embedded depth of the two ends of the specimen strip is the same, and the specimen strip is in a straightening state, so that the specimen strip can be embedded into the wax block in a straight manner, the embedded depth of a plurality of specimen strips is the same, and the plurality of specimen strips are positioned in the same horizontal plane; when the embedding depth needs to be adjusted, the second bolt 32 is screwed to move the fourth plate 29 upward or downward, the embedding depth is increased when the fourth plate 29 moves upward, and the embedding depth is decreased when the fourth plate 29 moves downward.
According to the invention, the second flat plate 9 is automatically leveled through the liquid column and the piston 7, a horizontal and stable reference surface can be always provided for embedding the specimen strip, and the ideal effects that a single specimen strip is straight and a plurality of specimen strips are positioned in the same horizontal plane can be achieved by matching with the constant compressible amount of the two telescopic rods.
Claims (10)
1. The pathological specimen embedding device is characterized by comprising a base consisting of supporting legs (1) and a horizontal first flat plate (2), wherein a plurality of piston cylinders (3) uniformly distributed on the circumference and a liquid storage bottle (4) are arranged on the upper surface of the first flat plate (2), the bottom of each piston cylinder (3) is communicated with the bottom of the liquid storage bottle (4) through a pipeline (5), a partition plate (6) capable of moving up and down is arranged in the liquid storage bottle (4), the side wall of each partition plate (6) is attached to the inner wall of the corresponding liquid storage bottle (4), and the partition plate (6) moves upwards to seal pipe openings of the plurality of pipelines (5) on the side wall of the corresponding liquid storage bottle (4); a piston (7) is installed in each piston cylinder (3), a vertical rod (8) is fixed at the upper end of each piston (7), a horizontal second flat plate (9) is arranged above the first flat plate (2), the second flat plate (9) is borne by the vertical rods (8), a horizontal third flat plate (10) capable of moving up and down is arranged below the first flat plate (2), a plurality of vertical plungers (11) which correspond to the piston cylinders (3) one by one are uniformly distributed on the circumference of the third flat plate (10), the upper end of each plunger (11) penetrates through the first flat plate (2) and extends into the corresponding piston cylinder (3), and the third flat plate (10) moves upwards to drive the plungers (11) to move upwards synchronously; the upper surface of the second flat plate (9) is provided with two vertical telescopic rods which are symmetrically arranged left and right, the upper end of each telescopic rod is provided with a clamp (12), and the clamps (12) can move downwards along with the telescopic rods.
2. The pathological specimen embedding device according to claim 1, wherein a vertical first bolt (13) penetrates through the third plate (10), the upper end of the first bolt (13) is in threaded fit with the first plate (2), and the third plate (10) can be driven to move upwards by rotating the first bolt (13) so as to push the plungers (11) to move upwards synchronously.
3. The pathological specimen embedding device according to claim 1, wherein a plurality of vertical first guide rods (14) are fixed on the lower surface of the second flat plate (9), a plurality of vertical first guide holes (15) corresponding to the first guide rods (14) in a one-to-one manner are formed in the first flat plate (2), the lower end of each first guide rod (14) penetrates into the corresponding first guide hole (15), and the diameter of each first guide hole (15) is larger than that of each first guide rod (14).
4. The pathological specimen embedding device according to claim 1, wherein a plurality of first tension springs (16) are connected between the first flat plate (2) and the second flat plate (9) and are evenly distributed on the circumference.
5. The pathological specimen embedding device according to claim 1, wherein each piston (7) is provided with a vertical air release hole (17), a horizontal floating plate (19) is hung on the lower surface of the piston (7) through a pull rope (18), and the air release holes (17) can be closed by upward movement of the floating plate (19).
6. The pathological specimen embedding device according to claim 1, wherein the telescopic rod is formed by coaxially sleeving an inner rod (20) and an outer rod (21), the lower end of the outer rod (21) is fixed on the second flat plate (9), a compression spring (22) is installed between the upper end of the inner rod (20) and the upper end of the outer rod (21), and the inner rods (20) of the two compression rods have the same height capable of being compressed downwards.
7. The pathological specimen embedding device according to claim 6, wherein a horizontal screw rod (23) is fixed at the upper end of each inner rod (20), a sliding sleeve (24) is sleeved on each screw rod (23), two clamps (12) are fixed on the two sliding sleeves (24) in a one-to-one correspondence mode and face downwards, a first nut (25) is screwed on each screw rod (23), the sliding sleeves (24) are located between the first nuts (25) and the inner rods (20), and the positions of the sliding sleeves (24) on the screw rods (23) can be adjusted by screwing the first nuts (25).
8. The pathological specimen embedding device according to claim 7, wherein each screw rod (23) is screwed with a second nut (26) between the sliding sleeve (24) and the inner rod (20), each second nut (26) is fixed with a fixing rod (27) facing downwards vertically, a horizontal heating wire (28) is connected between the lower ends of the two fixing rods (27), and the heating wire (28) is lower than the clamp (12).
9. The pathological specimen embedding device according to claim 1, wherein a horizontal fourth flat plate (29) is arranged above the second flat plate (9), a second tension spring (30) is connected between the second flat plate (9) and the fourth flat plate (29), a plurality of vertical second guide rods (31) are fixed on the lower surface of the fourth flat plate (29), the second guide rods (31) penetrate through the second flat plate (9), a vertical second bolt (32) is screwed on the second flat plate (9), the upper end of the second bolt (32) is propped against the lower surface of the fourth flat plate (29), and the height of the fourth flat plate (29) can be adjusted by screwing the second bolt (32).
10. The pathological specimen embedding device according to claim 1, wherein a vertical third bolt (33) is screwed on the top of the liquid storage bottle (4), the lower end of the third bolt (33) is rotatably connected with the partition plate (6), and the partition plate (6) can be driven to move up and down by the third bolt (33).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010064435.8A CN110895220B (en) | 2020-01-20 | 2020-01-20 | Pathological specimen embedding device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010064435.8A CN110895220B (en) | 2020-01-20 | 2020-01-20 | Pathological specimen embedding device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110895220A CN110895220A (en) | 2020-03-20 |
| CN110895220B true CN110895220B (en) | 2021-01-29 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202010064435.8A Expired - Fee Related CN110895220B (en) | 2020-01-20 | 2020-01-20 | Pathological specimen embedding device |
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| Country | Link |
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| CN (1) | CN110895220B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113551966B (en) * | 2021-07-06 | 2023-07-28 | 四川大学华西第二医院 | Packaging equipment for pathological examination specimen |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN207456912U (en) * | 2017-09-26 | 2018-06-05 | 西安培华学院 | A kind of pathologic tissue packing die |
| CN108437460B (en) * | 2018-05-04 | 2020-09-11 | 芜湖市智行天下工业设计有限公司 | A shock attenuation formula automatic levelling device for 3D printer |
| JP7171019B2 (en) * | 2018-06-22 | 2022-11-15 | 村角工業株式会社 | Embedding cassette for pathological examination |
| CN208554195U (en) * | 2018-07-04 | 2019-03-01 | 南京诺齐生物科技有限公司 | A kind of microcapsule embedded phytosterol preparation facilities |
| CN208476645U (en) * | 2018-07-12 | 2019-02-05 | 武汉巴菲尔生物技术服务有限公司 | A kind of pathological examination embedding machine |
| CN109596404A (en) * | 2019-01-15 | 2019-04-09 | 张庆明 | A kind of biology paraffin wax embedding |
| CN109764947A (en) * | 2019-01-17 | 2019-05-17 | 广州市丹爵通讯科技有限公司 | A kind of organic waste weighing-appliance with Level tune function |
| CN110307290B (en) * | 2019-06-28 | 2021-02-26 | 徐州鑫旭机械制造有限公司 | Be used for mining machinery vibration damping mount |
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2020
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| CN110895220A (en) | 2020-03-20 |
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Granted publication date: 20210129 |