CN110891555B - 用于治疗非因感染引起的刺激的滴眼剂 - Google Patents

用于治疗非因感染引起的刺激的滴眼剂 Download PDF

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Publication number
CN110891555B
CN110891555B CN201880029944.8A CN201880029944A CN110891555B CN 110891555 B CN110891555 B CN 110891555B CN 201880029944 A CN201880029944 A CN 201880029944A CN 110891555 B CN110891555 B CN 110891555B
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China
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use according
ophthalmic formulation
epithelial cells
treatment comprises
treatment
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CN201880029944.8A
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English (en)
Chinese (zh)
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CN110891555A (zh
Inventor
沙布泰·迪克斯坦
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Redwood Research And Development Co ltd
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Redwood Research And Development Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN201880029944.8A 2017-03-05 2018-02-19 用于治疗非因感染引起的刺激的滴眼剂 Active CN110891555B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762467139P 2017-03-05 2017-03-05
US62/467,139 2017-03-05
PCT/IL2018/050184 WO2018163151A1 (en) 2017-03-05 2018-02-19 Eye drops for treatment of irritation not due to infection

Publications (2)

Publication Number Publication Date
CN110891555A CN110891555A (zh) 2020-03-17
CN110891555B true CN110891555B (zh) 2023-12-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880029944.8A Active CN110891555B (zh) 2017-03-05 2018-02-19 用于治疗非因感染引起的刺激的滴眼剂

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Country Link
US (2) US11033513B2 (enExample)
EP (2) EP3592339B1 (enExample)
JP (1) JP7258778B2 (enExample)
KR (1) KR102652879B1 (enExample)
CN (1) CN110891555B (enExample)
AU (1) AU2018230262B2 (enExample)
BR (1) BR112019018367A2 (enExample)
CA (1) CA3055523C (enExample)
ES (1) ES3036888T3 (enExample)
IL (1) IL269133B2 (enExample)
MX (1) MX388961B (enExample)
PL (1) PL3592339T3 (enExample)
RU (1) RU2019130955A (enExample)
WO (1) WO2018163151A1 (enExample)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1202108A (zh) * 1995-10-12 1998-12-16 大制药株式会社 治疗眼病的喹诺酮衍生物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL80298A (en) 1986-10-14 1993-01-31 Res & Dev Co Ltd Eye drops
US5895645A (en) * 1995-01-31 1999-04-20 Bausch & Lomb Incorporated Opthalmic solution for artificial tears
JP3093661B2 (ja) * 1995-10-12 2000-10-03 大塚製薬株式会社 眼疾患治療剤
IL120005A (en) * 1997-01-14 2000-08-31 Ramot University Authority Of Pharmaceutical compositions for the treatment of the eye
US5800807A (en) * 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
IL168603A (en) * 2005-05-16 2011-05-31 Resdevco Res And Dev Co Pharmaceutical or cosmetic composition for the prevention and treatment of irritation of mucous cells or skin cells
DE102005055275A1 (de) 2005-11-17 2007-05-24 Ursapharm Arzneimittel Gmbh & Co. Kg Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung
IL212725A (en) * 2011-05-05 2016-06-30 Resdevco Res And Dev Co Glycerol Preparation for Non-surgical Conjunctivochalysis
KR102107471B1 (ko) 2011-11-24 2020-05-07 토요 슈가 리파이닝 컴퍼니 리미티드 각결막 보호제 또는 각결막 장해 억제제
US9278132B2 (en) 2012-02-13 2016-03-08 Bausch & Lomb Incorporated Ophthalmic pharmaceutical compositions and methods of making and using same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1202108A (zh) * 1995-10-12 1998-12-16 大制药株式会社 治疗眼病的喹诺酮衍生物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Isotonic Glycerol and Sodium Hyaluronate Containing Artificial Tear Decreases Conjunctivochalasis after One and Three Months: A Self-Controlled, Unmasked Study;Huba J. Kiss等;《PLoS One》;20150714;第10卷(第7期);第1-13页和Supporting information *

Also Published As

Publication number Publication date
CA3055523A1 (en) 2018-09-13
EP4385565A2 (en) 2024-06-19
KR20190129065A (ko) 2019-11-19
EP3592339A1 (en) 2020-01-15
JP7258778B2 (ja) 2023-04-17
US20190388361A1 (en) 2019-12-26
CN110891555A (zh) 2020-03-17
US11426361B2 (en) 2022-08-30
KR102652879B1 (ko) 2024-03-29
AU2018230262B2 (en) 2024-01-18
CA3055523C (en) 2024-10-01
EP3592339C0 (en) 2025-04-30
IL269133B1 (en) 2024-05-01
MX388961B (es) 2025-03-20
EP3592339B1 (en) 2025-04-30
EP4385565A3 (en) 2024-08-21
US20210186892A1 (en) 2021-06-24
AU2018230262A1 (en) 2019-09-26
WO2018163151A1 (en) 2018-09-13
PL3592339T3 (pl) 2025-09-01
RU2019130955A3 (enExample) 2021-06-24
BR112019018367A2 (pt) 2020-04-07
US11033513B2 (en) 2021-06-15
RU2019130955A (ru) 2021-04-07
JP2020509092A (ja) 2020-03-26
MX2019010471A (es) 2020-02-12
IL269133A (en) 2019-11-28
IL269133B2 (en) 2024-09-01
ES3036888T3 (en) 2025-09-25

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