CN110856734A - Traditional Chinese medicine composition for preventing wound infection and preparation method thereof - Google Patents

Traditional Chinese medicine composition for preventing wound infection and preparation method thereof Download PDF

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CN110856734A
CN110856734A CN201810951954.9A CN201810951954A CN110856734A CN 110856734 A CN110856734 A CN 110856734A CN 201810951954 A CN201810951954 A CN 201810951954A CN 110856734 A CN110856734 A CN 110856734A
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章金坤
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/10Peat; Amber; Turf; Humus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing wound infection and a preparation method thereof, wherein the traditional Chinese medicine composition comprises the following substances in parts by mass: 8-20 parts of sheep's mouth, 8-10 parts of lygodium japonicum, 3-20 parts of radix zanthoxyli, 15-25 parts of bulbus fritilariae, 2-18 parts of corn starch, 5-10 parts of talcum powder, 2-18 parts of sea stone, 2-18 parts of magma ash, 3-20 parts of almond, 6-10 parts of stearic acid and the balance of water; the preparation process is simple and has no pollution; the use method is simple, simple and easy to use, and meets the household requirements; the raw materials have wide sources and low price, and the economic burden of people is reduced.

Description

Traditional Chinese medicine composition for preventing wound infection and preparation method thereof
Technical Field
The invention relates to a traditional Chinese medicine composition for preventing wound infection and a preparation method thereof.
Background
Wound infection is a pathological reaction that after pathogenic microorganisms invade an organism through a wound, the pathogenic microorganisms grow and reproduce in the organism, so that the normal functions, metabolism and tissue structure of the organism are damaged, and tissue injury pathological changes are caused. After the body is attacked by pathogens, various defense functions can be mobilized to eliminate the pathogens and their toxic products, so as to restore the body's relative stability. Whether a pathogen can cause an infection after invading the body depends mainly on the virulence of the pathogen and the body's resistance.
Symptoms of wound infection:
1. some common superficial wound infections often present with symptoms of wound pain, tenderness, local swelling, redness and warmth.
2. Purulent secretion is often generated in some deeper wounds, and simultaneously, the patients also have symptoms of pain and red swelling of the mountain ditches and fever in some patients.
3. If the wound infection of the patient is not controlled in time, the infection is continuously aggravated, ulcer and even gangrene appear at the wound part, and serious patients even have systemic poisoning symptoms such as high fever and coma.
At present, most of methods for treating wound infection use antibiotic western medicines, which have great toxic and side effects and drug resistance and are not suitable for long-term use.
Through search, the following published documents about the traditional Chinese medicine liquid for preventing and treating wound infection are found:
1. chinese patent, application (patent) No. CN200410102766.7 name: chinese medicinal composition for treating pyocutaneous disease and wound infection; publication (bulletin) No.: CN1651012 application (patent rights) man: a beng celebration; 100085 Qingyuang No. 1 building No. 2 Unit No. 102 in Haihe district, Beijing; and (3) abstract: the invention provides a traditional Chinese medicine composition for treating pyocutaneous disease and wound infection, which is mainly prepared from the following raw material medicines in parts by weight: 1400 parts of soybean oil, 300 parts of willow bark, 4-6 parts of frankincense, 4-6 parts of myrrh, 3-5 parts of dragon's blood and 230 parts of black snake 170-. The medicine is used for treating wound infection, has the functions of relieving swelling and pain, removing blood stasis and expelling pus, promotes the growth of granulation tissues of the wound and accelerates the healing of the wound.
2. Chinese patent, application (patent) No. CN200910143182.7 name: a Chinese medicinal preparation for external use for treating surgical wound infection and its preparation method are provided; publication (bulletin) No.: CN101543565 (patent) applicant: bu Wu; 161041 Fulare base region Feicuilabao 3-unit 301 room in Qizihaer city, Heilongjiang province; and (3) abstract: a Chinese medicinal preparation for external use for treating surgical wound infection and its preparation method are provided. The traditional Chinese medicinal materials such as pangolin scales, dragon's blood, pseudo-ginseng, red halloysite, frankincense, myrrh, vermilion, catechu, pearl powder, calcined dragon bone, calomel, borneol, sesame oil and the like are used as raw materials, the medicine properties are mild, no toxic or side effect is caused, the medicine is less in dosage, the medicine change is simple, the effect is good, the formula is tight, the effects of removing the necrotic tissue and extracting the toxin, promoting blood circulation to remove blood stasis, promoting tissue regeneration and closing up, tonifying qi and benefiting blood are achieved, the symptoms and the root causes are treated, the curative effect is rapid; the preparation method conforms to the traditional Chinese medicine process, has simple equipment, short production period, energy and water conservation, low product cost and no pollution, and relieves the adverse reaction caused by frequent replacement of external application medicines and multiple times of operation for removing necrotic infected tissues in the conventional surgical treatment of wound infection.
3. Chinese patent, application number: cn201210435957.x name: a medicament for treating wound infections, publication (bulletin) No.: CN102920776A, applicant (patentee): su Jia minister, inventor (designer): su Jia Chen; address: 11 groups of abstracts of village, four miles, ying village, ten miles in Xiangcheng county, Henan province: a medicine for treating wound infection, which belongs to the technical field of medical products. The medicine of the invention consists of croton, castor bean, walnut and lard. The paste must be formed by hitting a sapphire plate with a bluestone machine. The raw pig leaf lard is prepared from aged oil prepared by wintery as far as possible. The four traditional Chinese medicines are compatible to play a unique curative effect together. The medicine composition is prepared by adopting pure natural plants and animals as raw materials according to a certain process, has unique curative effect on skin wound infection, and has high curative effect and no relapse after healing. The medicine has the advantages of wide raw material source, low cost, simple preparation method and no three-waste discharge in production.
Disclosure of Invention
The invention aims to solve the technical problem of providing a traditional Chinese medicine composition for preventing wound infection and a preparation method thereof, which can prevent and treat wound infection, have a pure traditional Chinese medicine formula, have no toxic or side effect, have high curative effect and are not easy to relapse after healing.
In order to solve the problems, the invention adopts the following technical scheme:
a traditional Chinese medicine composition for preventing wound infection comprises the following substances in parts by mass:
8-20 parts of sheep's mouth
8-10 parts of lygodium japonicum thunb
3-20 parts of radix zanthoxyli
Sichuan fritillary bulb 15-25 weight portions
2-18 parts of corn starch
5-10 parts of talcum powder
2-18 parts of sea stone
2-18 parts of magma ash
3-20 parts of almond
Stearic acid 6-10 parts
The balance being water.
Preferably, the composition comprises the following substances in percentage by mass: 12 parts of sheep's mouth, 10 parts of lygodium japonicum, 15 parts of radix zanthoxyli, 25 parts of bulbus fritilariae, 5 parts of corn starch, 10 parts of talcum powder, 5 parts of sea stone, 15 parts of magma ash, 10 parts of almond, 10 parts of stearic acid and the balance of water.
Preferably, the composition comprises the following substances in percentage by mass: 10 parts of sheep's mouth, 10 parts of lygodium japonicum, 15 parts of radix zanthoxyli, 15 parts of bulbus fritilariae, 15 parts of corn starch, 5 parts of talcum powder, 15 parts of sea stone, 5 parts of magma ash, 15 parts of almond, 6 parts of stearic acid and the balance of water.
Preferably, the composition comprises the following substances in percentage by mass: 11 parts of sheep gizzard-membrane, 9 parts of lygodium japonicum, 12 parts of radix zanthoxyli, 20 parts of bulbus fritillariae cirrhosae, 10 parts of corn starch, 8 parts of talcum powder, 10 parts of sea stone, 10 parts of magma ash, 12 parts of almond, 8 parts of stearic acid and the balance of water.
A preparation method of a traditional Chinese medicine composition for preventing wound infection comprises the following steps:
1) selecting 8-20 parts of sheep's mouth, 8-10 parts of lygodium japonicum, 3-20 parts of radix zanthoxyli, 15-25 parts of bulbus fritillariae cirrhosae, 2-18 parts of corn starch, 5-10 parts of talcum powder, 2-18 parts of sea stone, 2-18 parts of magma ash, 3-20 parts of almond and 6-10 parts of stearic acid; solarizing the selected components in the sun at the solarization temperature of 35-38 ℃ until the water content of the components is lower than 3%;
2) grinding the dried components in a classified manner to obtain fine particles with the particle size of 100 meshes and 250 meshes, and then uniformly mixing the fine particles of the components to obtain a mixture;
3) boiling the mixture obtained in the step 2) in water, continuing to boil for 20-35 min, turning to low fire, and continuing to boil until the mixture is pasty to obtain paste;
4) brushing the paste obtained in the step 3) on sterile cotton cloth to obtain the traditional Chinese medicine composition for preventing wound infection.
The invention has the beneficial effects that:
1. the invention relates to a Chinese medicinal composition for treating wound infection, which is prepared from a plurality of Chinese medicinal herbs including sheep's gizzard-membrane, climbing fern vine, shiny-leaved pricklyash, tendril-leaved fritillary bulb, corn starch, talcum powder, sea stone, magma ash, almond and stearic acid.
2. The invention does not add any artificially synthesized additive and does not use antibiotics.
3. The preparation process is simple and has no pollution; the use method is simple, simple and easy to use, and meets the household requirements; the raw materials have wide sources and low price, and the economic burden of people is reduced.
Detailed Description
The following detailed description of the preferred embodiments of the present invention is provided to enable those skilled in the art to more readily understand the advantages and features of the present invention and to clearly and unequivocally define the scope of the present invention.
A traditional Chinese medicine composition for preventing wound infection comprises the following substances in parts by mass:
8-20 parts of sheep's mouth
8-10 parts of lygodium japonicum thunb
3-20 parts of radix zanthoxyli
Sichuan fritillary bulb 15-25 weight portions
2-18 parts of corn starch
5-10 parts of talcum powder
2-18 parts of sea stone
2-18 parts of magma ash
3-20 parts of almond
Stearic acid 6-10 parts
The balance being water.
The invention has the beneficial effects that:
1. the invention relates to a Chinese medicinal composition for treating wound infection, which is prepared from a plurality of Chinese medicinal herbs including sheep's gizzard-membrane, climbing fern vine, shiny-leaved pricklyash, tendril-leaved fritillary bulb, corn starch, talcum powder, sea stone, magma ash, almond and stearic acid.
2. The invention does not add any artificially synthesized additive and does not use antibiotics.
3. The preparation process is simple and has no pollution; the use method is simple, simple and easy to use, and meets the household requirements; the raw materials have wide sources and low price, and the economic burden of people is reduced.
Example 1
1) Selecting 12 parts of sheep's mouth, 10 parts of lygodium japonicum, 15 parts of radix zanthoxyli, 25 parts of bulbus fritilariae, 5 parts of corn starch, 10 parts of talcum powder, 5 parts of sea rock, 15 parts of magma ash, 10 parts of almond and 10 parts of stearic acid; solarizing the selected components in the sun at the solarization temperature of 35-38 ℃ until the water content of the components is lower than 3%;
2) grinding the dried components in a classified manner to obtain fine particles with the particle size of 100 meshes and 250 meshes, and then uniformly mixing the fine particles of the components to obtain a mixture;
3) boiling the mixture obtained in the step 2) in water, continuing to boil for 20-35 min, turning to low fire, and continuing to boil until the mixture is pasty to obtain paste;
4) brushing the paste obtained in the step 3) on sterile cotton cloth to obtain the traditional Chinese medicine composition for preventing wound infection.
Jia in 45 years old, Zhejiang people, when building site plate bricks fall off and crush the foot surfaces, the foot surfaces are inflamed and purulent after bacterial infection, and after multiple treatments, the inflammation of the wound surfaces is obviously improved after 1-2 weeks by using the traditional Chinese medicine composition for preventing wound surface infection, and the traditional Chinese medicine composition is suitable for scabbing and falling off of the wound surfaces after 3 weeks.
Example 2
1) Selecting 10 parts of sheep's mouth, 10 parts of lygodium japonicum, 15 parts of radix zanthoxyli, 15 parts of bulbus fritilariae, 15 parts of corn starch, 5 parts of talcum powder, 15 parts of sea rock, 5 parts of magma ash, 15 parts of almond and 6 parts of stearic acid; solarizing the selected components in the sun at the solarization temperature of 35-38 ℃ until the water content of the components is lower than 3%;
2) grinding the dried components in a classified manner to obtain fine particles with the particle size of 100 meshes and 250 meshes, and then uniformly mixing the fine particles of the components to obtain a mixture;
3) boiling the mixture obtained in the step 2) in water, continuing to boil for 20-35 min, turning to low fire, and continuing to boil until the mixture is pasty to obtain paste;
4) brushing the paste obtained in the step 3) on sterile cotton cloth to obtain the traditional Chinese medicine composition for preventing wound infection.
The inflammation and pus of the wound surface after bacterial infection of knee is caused by wrestling of a person aged at 35 years old and Zhejiang, and the inflammation and pus of the wound surface are not obviously improved after multiple treatments, the inflammation condition of the wound surface is obviously improved after 1 week by using the traditional Chinese medicine composition for preventing wound surface infection, and the traditional Chinese medicine composition is suitable for scabbing and dropping the wound surface after 2 weeks.
Example 3
1) Selecting 11 parts of sheep fore, 9 parts of lygodium japonicum, 12 parts of radix zanthoxyli, 20 parts of bulbus fritilariae, 10 parts of corn starch, 8 parts of talcum powder, 10 parts of sea stone, 10 parts of magma ash, 12 parts of almond and 8 parts of stearic acid; solarizing the selected components in the sun at the solarization temperature of 35-38 ℃ until the water content of the components is lower than 3%;
2) grinding the dried components in a classified manner to obtain fine particles with the particle size of 100 meshes and 250 meshes, and then uniformly mixing the fine particles of the components to obtain a mixture;
3) boiling the mixture obtained in the step 2) in water, continuing to boil for 20-35 min, turning to low fire, and continuing to boil until the mixture is pasty to obtain paste;
4) brushing the paste obtained in the step 3) on sterile cotton cloth to obtain the traditional Chinese medicine composition for preventing wound infection.
After being treated for multiple times, the inflammation condition of the wound surface is obviously improved after 1 week, and the traditional Chinese medicine composition for preventing the wound surface infection is applicable to scabbing and then falling off after 3 weeks.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are given by way of illustration of the principles of the present invention, and that various changes and modifications may be made without departing from the spirit and scope of the invention as defined by the appended claims. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (5)

1. A traditional Chinese medicine composition for preventing wound infection is characterized in that: the material composition comprises the following components in percentage by mass:
8-20 parts of sheep's mouth
8-10 parts of lygodium japonicum thunb
3-20 parts of radix zanthoxyli
Sichuan fritillary bulb 15-25 weight portions
2-18 parts of corn starch
5-10 parts of talcum powder
2-18 parts of sea stone
2-18 parts of magma ash
3-20 parts of almond
Stearic acid 6-10 parts
The balance being water.
2. A traditional Chinese medicine composition for preventing wound infection according to claim 1, wherein: the material composition comprises the following components in percentage by mass: 12 parts of sheep's mouth, 10 parts of lygodium japonicum, 15 parts of radix zanthoxyli, 25 parts of bulbus fritilariae, 5 parts of corn starch, 10 parts of talcum powder, 5 parts of sea stone, 15 parts of magma ash, 10 parts of almond, 10 parts of stearic acid and the balance of water.
3. A traditional Chinese medicine composition for preventing wound infection according to claim 1, wherein: the material composition comprises the following components in percentage by mass: 10 parts of sheep's mouth, 10 parts of lygodium japonicum, 15 parts of radix zanthoxyli, 15 parts of bulbus fritilariae, 15 parts of corn starch, 5 parts of talcum powder, 15 parts of sea stone, 5 parts of magma ash, 15 parts of almond, 6 parts of stearic acid and the balance of water.
4. A traditional Chinese medicine composition for preventing wound infection according to claim 1, wherein: the material composition comprises the following components in percentage by mass: 11 parts of sheep gizzard-membrane, 9 parts of lygodium japonicum, 12 parts of radix zanthoxyli, 20 parts of bulbus fritillariae cirrhosae, 10 parts of corn starch, 8 parts of talcum powder, 10 parts of sea stone, 10 parts of magma ash, 12 parts of almond, 8 parts of stearic acid and the balance of water.
5. A method of preparing a Chinese medicinal composition for use in the prevention of wound infection as claimed in any one of claims 1 to 4, wherein: the method comprises the following steps:
selecting 8-20 parts of sheep's mouth, 8-10 parts of lygodium japonicum, 3-20 parts of radix zanthoxyli, 15-25 parts of bulbus fritillariae cirrhosae, 2-18 parts of corn starch, 5-10 parts of talcum powder, 2-18 parts of sea stone, 2-18 parts of magma ash, 3-20 parts of almond and 6-10 parts of stearic acid; solarizing the selected components in the sun at the solarization temperature of 35-38 ℃ until the water content of the components is lower than 3%;
grinding the dried components in a classified manner to obtain fine particles with the particle size of 100 meshes and 250 meshes, and then uniformly mixing the fine particles of the components to obtain a mixture;
boiling the mixture obtained in the step 2) in water, continuing to boil for 20-35 min, turning to low fire, and continuing to boil until the mixture is pasty to obtain paste;
brushing the paste obtained in the step 3) on sterile cotton cloth to obtain the traditional Chinese medicine composition for preventing wound infection.
CN201810951954.9A 2018-08-21 2018-08-21 Traditional Chinese medicine composition for preventing wound infection and preparation method thereof Pending CN110856734A (en)

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Application publication date: 20200303