CN110841010A - Medicine for treating pyelonephritis and preparation method thereof - Google Patents

Medicine for treating pyelonephritis and preparation method thereof Download PDF

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Publication number
CN110841010A
CN110841010A CN201911137127.7A CN201911137127A CN110841010A CN 110841010 A CN110841010 A CN 110841010A CN 201911137127 A CN201911137127 A CN 201911137127A CN 110841010 A CN110841010 A CN 110841010A
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parts
medicine
water
pyelonephritis
decocting
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熊丽
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a medicine for treating pyelonephritis and a preparation method thereof, and the medicine comprises the following raw materials in parts by weight: 18-22 parts of honeysuckle, 13-17 parts of eclipta alba, 18-22 parts of motherwort, 28-32 parts of plantain and 28-32 parts of couchgrass root. The preparation method comprises the following steps of taking the raw material medicines in parts by weight; soaking the above materials in 3 times of water for 20-30min, boiling with strong fire, decocting with slow fire for 25-35min, and collecting decoction; adding 2 times of water into the residue, decocting for 20-30min, and collecting decoction; mixing the two water decoctions. The medicine for treating pyelonephritis has the characteristics of quick response, good curative effect, safety and no toxic or side effect.

Description

Medicine for treating pyelonephritis and preparation method thereof
Technical Field
The invention belongs to the field of traditional Chinese medicines, and particularly relates to a medicine for treating pyelonephritis, and a preparation method of the medicine for treating pyelonephritis.
Background
Pyelonephritis (pyelonephritis) is inflammation of renal pelvis and renal parenchyma caused by pathogenic microorganisms, often accompanied by lower urinary tract infection. Most are caused by gram-negative bacilli infection and are classified into acute and chronic types. Acute pyelonephritis is characterized by acute interstitial inflammation and renal tubular necrosis related to infection, and patients have symptoms of fever, frequent micturition, urgent micturition, odynuria, bacteriuria and the like, and can be quickly cured by using effective antibacterial drugs if no complex factors exist. Chronic pyelonephritis is caused by anatomical or functional abnormality of urinary tract, and in addition to bacterial urinary sensation, can also result in scar formation of renal pelvis and renal calyx, unsmooth appearance of kidney or different sizes of two kidneys, has latent disease, is easy to recur, and can cause chronic renal insufficiency.
At present, western medicine treatment for treating pyelonephritis generally adopts antibiotic medicines, although the effect is quick and the symptoms can be relieved, the long-term taking of the medicine can bring larger side effect to renal patients with defective renal functions. The traditional Chinese medicine has small adverse reaction during treatment, the medicines on the market are not ideal at present, most of the traditional Chinese medicines have more components, and the liver and kidney are heavier after long-term administration, so the traditional Chinese medicine is not suitable for long-term use.
Disclosure of Invention
The invention aims to provide a medicine for treating pyelonephritis, which has the advantages of quick response, good curative effect and no toxic or side effect.
The invention also aims to provide a preparation method of the medicine for treating pyelonephritis.
The invention relates to a medicine for treating pyelonephritis, which comprises the following raw materials in parts by weight:
18-22 parts of honeysuckle, 13-17 parts of eclipta alba, 18-22 parts of motherwort, 28-32 parts of plantain and 28-32 parts of couchgrass root.
The medicine for treating pyelonephritis is prepared from the following raw materials in parts by weight:
20 parts of honeysuckle, 15 parts of eclipta alba, 20 parts of motherwort, 30 parts of plantain and 30 parts of couchgrass root.
50 parts of longhairy antenoron herb is added for patients with calculus.
20 parts of plantain herb is added for patients with damp-heat.
The preparation method of the medicine for treating pyelonephritis comprises the following steps:
(1) taking the raw materials in parts by weight;
(2) soaking the above materials in 3 times of water for 20-30min, boiling with strong fire, decocting with slow fire for 25-35min, and collecting decoction; adding 2 times of water into the residue, decocting for 20-30min, and collecting decoction; mixing the two water decoctions.
Compared with the prior art, the invention has obvious beneficial effects, and the technical scheme can show that: the Chinese medicinal composition adopts honeysuckle, eclipta alba, motherwort herb, plantain herb and couchgrass root as raw materials, plays the effects of activating blood circulation, diminishing inflammation, inducing diuresis and treating stranguria through the synergistic effect of the medicaments, achieves the aim of treating pyelonephritis, and has good treatment effect on hypertension and gout. The medicine for treating pyelonephritis has the characteristics of quick response, good curative effect, safety and no toxic or side effect. The traditional Chinese medicine is used in 180 cases clinically, and the total effective rate is 90%.
Detailed Description
The beneficial effects of the drug of the present invention are further illustrated by the following test examples.
Test example: clinical observation 1 and clinical data of the medicine of the invention:
180 total cases, of which: age 28-76 years, 96 men and 84 women.
2. Diagnostic criteria:
the standard of curative effect for diagnosing the diseases of the traditional Chinese medicine.
3. The treatment method comprises the following steps:
the medicine obtained by the invention is orally taken 3 times a day, one dose is taken every two days, and one treatment course is one month.
4. The curative effect standard is as follows:
the effect is shown: disappearance of symptoms;
the method has the following advantages: the symptoms are obviously relieved;
and (4) invalidation: the symptoms are not obviously improved.
5. The treatment results are as follows:
when the medicine is used by patients, 153 cases of the medicine are effective, 9 cases of the medicine are effective, 18 cases of the medicine are ineffective, the effectual rate is 85 percent, and the total effective rate is 90 percent.
The preparation of the present medicament is illustrated by the following examples.
Example 1
A preparation method of a medicine for treating pyelonephritis comprises the following steps:
(1) weighing 18g of honeysuckle, 17g of eclipta alba, 18g of motherwort, 32g of plantain and 28g of couchgrass root;
(2) soaking the above materials in 3 times of water for 30min, boiling with strong fire, decocting with slow fire for 25min, and collecting decoction; adding 2 times of water into the residue, decocting for 30min, and collecting decoction; mixing the two water decoctions.
Example 2
A preparation method of a medicine for treating pyelonephritis comprises the following steps:
(1) weighing 20g of honeysuckle, 15g of eclipta alba, 20g of motherwort, 30g of plantain and 30g of couchgrass root;
(2) soaking the above materials in 3 times of water for 25min, boiling with strong fire, decocting with slow fire for 30min, and collecting decoction; adding 2 times of water into the residue, decocting for 25min, and collecting decoction; mixing the two water decoctions.
Example 3
A preparation method of a medicine for treating pyelonephritis comprises the following steps:
(1) weighing 22g of honeysuckle, 13g of eclipta alba, 22g of motherwort, 28g of plantain and 32g of couchgrass root;
(2) soaking the above materials in 3 times of water for 20min, boiling with strong fire, decocting with slow fire for 35min, and collecting decoction; adding 2 times of water into the residue, decocting for 20min, and collecting decoction; mixing the two water decoctions.
Example 4
A preparation method of a medicine for treating pyelonephritis comprises the following steps:
(1) weighing 20g of honeysuckle, 15g of eclipta alba, 20g of motherwort, 30g of plantain, 30g of couchgrass root and 50g of longhairy antenoron herb;
(2) soaking the above materials in 3 times of water for 25min, boiling with strong fire, decocting with slow fire for 30min, and collecting decoction; adding 2 times of water into the residue, decocting for 25min, and collecting decoction; mixing the two water decoctions.
Example 5
A preparation method of a medicine for treating pyelonephritis comprises the following steps:
(1) weighing 20g of honeysuckle, 15g of eclipta alba, 20g of motherwort, 30g of plantain, 30g of couchgrass root and 20g of plantain;
(2) soaking the above materials in 3 times of water for 25min, boiling with strong fire, decocting with slow fire for 30min, and collecting decoction; adding 2 times of water into the residue, decocting for 25min, and collecting decoction; mixing the two water decoctions.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, and any simple modification, equivalent change and modification made to the above embodiment according to the technical spirit of the present invention are within the scope of the present invention without departing from the technical spirit of the present invention.

Claims (5)

1. The medicine for treating pyelonephritis comprises the following raw materials in parts by weight:
18-22 parts of honeysuckle, 13-17 parts of eclipta alba, 18-22 parts of motherwort, 28-32 parts of plantain and 28-32 parts of couchgrass root.
2. The medicine for treating pyelonephritis as claimed in claim 1, which comprises the following raw materials in parts by weight:
20 parts of honeysuckle, 15 parts of eclipta alba, 20 parts of motherwort, 30 parts of plantain and 30 parts of couchgrass root.
3. A medicament as claimed in claim 1 or 2, wherein: 50 portions of lysimachia christinae hance are added for patients with calculi.
4. A medicament as claimed in claim 1 or 2, wherein: 20 portions of plantain herb is added for patients with damp-heat.
5. A medicament for the treatment of pyelonephritis as claimed in any of claims 1-4, which is prepared by a process comprising the steps of:
(1) taking the raw materials in parts by weight;
(2) soaking the above materials in 3 times of water for 20-30min, boiling with strong fire, decocting with slow fire for 25-35min, and collecting decoction; adding 2 times of water into the residue, decocting for 20-30min, and collecting decoction; mixing the two water decoctions.
CN201911137127.7A 2019-11-19 2019-11-19 Medicine for treating pyelonephritis and preparation method thereof Pending CN110841010A (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
CN201911137127.7A CN110841010A (en) 2019-11-19 2019-11-19 Medicine for treating pyelonephritis and preparation method thereof

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105596857A (en) * 2016-02-02 2016-05-25 刘运波 Traditional Chinese medicine for treating acute pyelonephritis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105596857A (en) * 2016-02-02 2016-05-25 刘运波 Traditional Chinese medicine for treating acute pyelonephritis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
广西中医药大学: "泌尿道感染", 《广西中医药》 *

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