CN110840978A

CN110840978A - A Chinese medicinal composition for treating rheumatic arthritis and rheumatoid arthritis, and medicated liquor containing the same

Info

Publication number: CN110840978A
Application number: CN201810867549.9A
Authority: CN
Inventors: 于金霞
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-08-02
Filing date: 2018-08-02
Publication date: 2020-02-28

Abstract

A Chinese medicinal composition and medicated liquor for treating rheumatism and rheumatoid arthritis, the composition is: comprises safflower, honey-fried licorice root, medlar, plantain seed, roasted nux vomica, earthworm, zaocys dhumnade, frankincense, myrrh, ground beetle, Chinese pine nodular branch, cinnamon, szechuan lovage rhizome, areca seed, dahurian angelica root, incised notopterygium rhizome, doubleteeth pubescent angelica root, tangerine peel, divaricate saposhnikovia root, largeleaf gentian root, pawpaw, eucommia bark, amur corktree bark, twotooth achyranthes. The medicinal liquor prepared from the components is mainly used for dispelling wind and eliminating dampness, promoting blood circulation and removing blood stasis, tonifying liver and kidney, dredging collaterals and relieving pain, and is prepared into medicinal liquor and paste for oral administration and external use, and the effect is better.

Description

A Chinese medicinal composition for treating rheumatic arthritis and rheumatoid arthritis, and medicated liquor containing the same

Technical Field

The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating rheumatic and rheumatoid arthritis.

Background

Rheumatism and rheumatoid arthritis belong to the category of arthralgia syndrome in traditional Chinese medicine, are caused by the imbalance of nutrition and defense of human bodies, the affection of pathogenic factors of wind, cold, dampness and heat, the conflict of endogenous phlegm, extravasated blood, toxic heat and vital qi and pathogens, the blockage of qi and blood of channels, skin, blood vessels, muscles and bones, joints and viscera is caused, the symptoms of limb pain, swelling, aching, numbness, heavy sticking, stiffness, deformation, improper joint flexion and extension, limited activity and the like are caused clinically, the viscera are affected seriously, the health of patients is seriously damaged, and the rheumatism and rheumatoid arthritis belongs to difficult miscellaneous diseases. The disease is usually more hidden and slower, the disease course is longer, and most of the diseases have hereditary tendency.

In Western medicine, the non-steroidal anti-inflammatory drug is a common drug for treating rheumatic arthritis and rheumatoid arthritis, such as pavlrin, methotrexate, Yisaipu and diclofenac sodium sustained-release capsules. However, the long-term administration of the traditional Chinese medicine has the defects of strong side effect, large stimulation to gastrointestinal tract, platelet aggregation, renal function damage and the like, so that the patient can not insist on taking the traditional Chinese medicine, the medication compliance of the patient is reduced, and the disease treatment is not facilitated, which limits the further use of the traditional Chinese medicine.

The traditional Chinese medicine is used as a treasure in Chinese culture tradition, has the characteristics of economy, time saving, convenient taking and small side effect, and is particularly suitable for chronic rheumatism and rheumatoid arthritis patients needing to be treated by taking the traditional Chinese medicine for a long time.

Disclosure of Invention

The invention aims to solve the technical problem of providing a preparation for treating rheumatic diseases and medicinal liquor thereof, which have good curative effect and small side effect.

The technical scheme for solving the technical problems is as follows: a traditional Chinese medicine preparation for treating rheumatic diseases comprises the following components in parts by weight:

20-40 parts of safflower, 30-50 parts of honey-fried licorice root, 30-50 parts of medlar, 40-60 parts of plantain seed, 3-8 parts of roasted nux vomica, 10-25 parts of earthworm, 10-25 parts of zaocys dhumnade, 10-25 parts of frankincense, 10-25 parts of myrrh, 10-25 parts of ground beetle, 10-25 parts of Chinese pine knot, 10-25 parts of cinnamon, 30-50 parts of ligusticum wallichii, 30-50 parts of betel nut, 30-50 parts of angelica dahurica, 30-50 parts of notopterygium root, 30-50 parts of radix angelicae pubescentis, 20-50 parts of dried orange peel, 20-50 parts of divaricate saposhnikovia root, 20-50 parts of large-leaved gentian, 20-50 parts of.

Preferably, the traditional Chinese medicine preparation for treating the rheumatic diseases is prepared by the following raw materials in parts by weight,

30-40 parts of safflower, 40-50 parts of honey-fried licorice root, 40-50 parts of wolfberry fruit, 50-60 parts of plantain seed, 5-8 parts of roasted nux vomica, 15-25 parts of earthworm, 15-25 parts of zaocys dhumnade, 15-25 parts of frankincense, 15-25 parts of myrrh, 15-25 parts of ground beetle, 15-25 parts of Chinese pine knot, 15-25 parts of cinnamon, 40-50 parts of ligusticum wallichii, 40-50 parts of betel nut, 40-50 parts of angelica dahurica, 40-50 parts of notopterygium root, 40-50 parts of radix angelicae pubescentis, 35-50 parts of dried orange peel, 35-50 parts of divaricate saposhnikovia root, 20-50 parts of large-leaved gentian, 20-50.

40 parts of safflower, 40 parts of honey-fried licorice root, 40 parts of medlar, 55 parts of plantain seed, 6 parts of roasted nux vomica, 20 parts of earthworm, 20 parts of zaocys dhumnade, 20 parts of frankincense, 20 parts of myrrh, 20 parts of ground beetle, 20 parts of Chinese pine node, 20 parts of cinnamon, 400 parts of ligusticum wallichii, 45 parts of betel nut, 45 parts of angelica root, 45 parts of notopterygium root, 45 parts of radix angelicae pubescentis, 40 parts of dried orange peel, 40 parts of divaricate saposhnikovia root, 40.

The invention also discloses a preparation method of the traditional Chinese medicine wine for treating rheumatic diseases, which comprises the following steps:

(1) weighing all the raw material medicaments in parts by weight;

(2) weighing the raw materials in the step (1), crushing and sieving;

(3) adding 10-15 times of 30-50 degrees of pure grain liquor according to the weight parts, and fully soaking the crushed raw material medicines for 24 hours to obtain the medicinal liquor.

The taking method comprises the following steps: is administered 3 times per day before meal. No more than 2 times per treatment, no dietetic restraint is needed.

The invention also discloses a preparation method of the traditional Chinese medicine paste for treating rheumatic diseases, which comprises the following steps:

(1) grinding the raw materials, and sieving with 30-50 mesh sieve to obtain powder;

(2) putting the powder prepared in the step (1) into pure sorghum liquor with the alcohol content of 35-50 degrees, and soaking for 20-30 days to obtain a mixed solution;

(3) filtering the mixed solution, and concentrating to obtain extract;

(4) and spreading the extract on gauze to obtain the ointment.

The using method comprises the following steps: the plaster is pasted on the pain part and is replaced within 48 hours.

The specific effects of the raw materials are as follows:

safflower: the source is as follows: dried flower of Carthamustatinorus L. of Compositae. Nature and taste: pungent and warm. It enters heart and liver meridians. The functional indications are as follows: promoting blood circulation, dredging channels, removing blood stasis and relieving pain. Can be used for treating amenorrhea, dysmenorrhea, lochiorrhea, abdominal mass, thoracic obstruction, cardialgia, abdominal pain due to blood stasis, pricking pain in chest and hypochondrium, traumatic injury, and pyocutaneous disease with swelling and pain.

Honey-fried licorice root: the source is as follows: dried root of Glycyrrhiza glabra, Glycyrrhiza infliximaiflata Bat. or Glycyrrhiza glabra L. of Leguminosae. Nature and taste: sweet and neutral. It enters heart, lung, spleen and stomach meridians. The functional indications are as follows: invigorating spleen and replenishing qi, clearing away heat and toxic material, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the drugs. Can be used for treating weakness of spleen and stomach, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limb spasm, pain, carbuncle, swelling, sore, and drug toxicity and strong nature.

Wolfberry fruit: the source is as follows: dried ripe fruit of Lycium barbarum L. of Solanaceae family. Nature and taste: sweet and neutral. It enters liver and kidney meridians. The functional indications are as follows: nourishing liver and kidney, replenishing vital essence and improving eyesight. Can be used for treating asthenia, soreness of waist and knees, vertigo, tinnitus, internal heat, diabetes, blood deficiency, sallow complexion, and blurred vision.

Plantain seed: the source is as follows: dried mature seeds of plantagaoastica l. or plantagaodepressa willd. plantago plantagina. Nature and taste: sweet and slightly cold. It enters liver, kidney, lung and small intestine meridians. The functional indications are as follows: clearing away heat, promoting urination, eliminating dampness, treating stranguria, improving eyesight, and eliminating phlegm. Can be used for treating edema, heat stranguria, pain, summer-heat dampness, diarrhea, conjunctival congestion, swelling and pain, and cough due to phlegm-heat.

Nux vomica: the source is as follows: dried mature seed of Loganiaceae plant Strychnosnuxvomica L. Nature and taste: bitter and warm; it is toxic. It enters liver and spleen meridians. The functional indications are as follows: unblock collaterals to alleviate pain, dissipate nodulation and resolve swelling. Can be used for treating rheumatism, numbness, paralysis, traumatic injury, carbuncle, cellulitis, and swelling and pain; sequela of poliomyelitis, rheumatoid arthralgia. The nux vomica is processed into a product because of high toxicity.

Earthworm: the source is as follows: dried bodies of the giant lumbricus Pheretima aspergillum (E. Perrier), Pheretima vulgaris Chen, Pheretima Williamsi Williamsii, Pheretima agallelmili (Michaelsen) or Pheretima aspecifera Michaelsen of Meretridae. Nature and taste: salty and cold. It enters liver, spleen and bladder meridians. The functional indications are as follows: clear heat and calm fright, dredge meridians, relieve asthma and induce diuresis. Can be used for treating hyperpyrexia, unconsciousness, epilepsy, convulsion, arthralgia, numbness of limbs, hemiplegia, cough and asthma due to lung heat, oliguria, edema, and hypertension.

Black-tail snake: also called Zaocys, Jian-spinal snake, black wind snake, yellow wind snake, Jian-spinal black-tail snake. The source is as follows: dried bodies of Zaocys dhumnades (Cantor) belonging to family Colubridae. Nature and taste: sweet and neutral. It enters liver meridian. The functional indications are as follows: dispel wind, unblock collaterals, stop convulsions. Can be used for treating rheumatism, numbness, spasm, facial distortion, hemiplegia, convulsion, tetanus, leprosy, scabies, and lymphoid tuberculosis.

Frankincense: the source is as follows: boswellia carterii Birdw [ B. sacraFluek ] of Boswellia of Burseraceae, Boswellia Birdw, and Boswellia staphyla B. negectia M. Moore, etc., and the oleoresin exuded from the wounds of the trunk and skin portions of the plants are used as the medicine. Nature and taste: pungent, bitter and warm. The functional indications are as follows: promoting blood circulation to arrest pain. Can be used for treating pain of heart and abdomen, spasm of tendons and vessels, traumatic injury, skin ulcer, carbuncle, and swelling and pain; it can be used topically for detumescence and granulation promotion.

Myrrh: the source is as follows: oleoresin exuded from trunk and bark of Commiphora myrrha Engl [ C. molmol Engl ] of Commiphora genus of Burseraceae family and other plants of the same genus. Nature and taste: bitter and neutral. The functional indications are as follows: dispel blood stasis and alleviate pain, resolve swelling and promote tissue regeneration for external use. Can be used for treating traumatic injury, blood stasis, swelling and pain, carbuncle, cellulitis, and pain of chest and abdomen; it is indicated for long-term sore without astringency.

Ground beetle: the source is as follows: dried female insect of Eupolyphagasinensis Walker or Stelephaganthyi (Boleny) belonging to family Trionychidae. Nature and taste: salty and cold; has little toxicity. It enters liver meridian. The functional indications are as follows: to break blood stasis and continue the muscles and bones. Can be used for treating fracture of tendons and bones, amenorrhea due to blood stasis, and abdominal mass.

And (3) joint of Chinese pine: the source is as follows: pine knots of Pinus pinustabulaeformis Carr, or nodules that develop after the pine tree is diseased. Nature and taste: bitter and warm. The functional indications are as follows: dispel wind and dampness, activate collaterals and alleviate pain. Can be used for treating rheumatic arthralgia, lumbago, skelalgia, Kaschin-Beck disease, and traumatic injury with swelling and pain.

Cinnamon: the source is as follows: dried bark of Cinnamomum cassia Cassia Presl of Lauraceae. Nature and taste: pungent and sweet with big heat. It enters kidney, spleen, heart and liver meridians. The functional indications are as follows: tonify fire and strengthen yang, guide fire to the origin, dispel cold and alleviate pain, activate blood and dredge channels. Can be used for treating sexual impotence, cold womb, psychroalgia of waist and knee, asthma due to kidney deficiency, vertigo due to yang deficiency, conjunctival congestion, pharyngalgia, psychroalgia of heart and abdomen, vomiting and diarrhea due to deficiency cold, cold hernia, galloping, amenorrhea, and dysmenorrhea.

Ligusticum wallichii: the source is as follows: dried rhizome of Ligusticum chuanxiong Hort (or Ligusticum wallichiifranch.) belonging to Umbelliferae family. Nature and taste: pungent and warm. It enters liver, gallbladder and pericardium meridians. The functional indications are as follows: promote blood circulation and move qi, dispel wind and alleviate pain. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal pain, pricking pain in chest and hypochondrium, traumatic injury, swelling and pain, headache, and rheumatalgia.

Betel nut: the source is as follows: dried mature seed of Areca catechu L. of Palmae. Nature and taste: bitter, pungent and warm. It enters stomach and large intestine meridians. The functional indications are as follows: kill parasites, remove food retention, descend qi, promote diuresis and check malaria. Can be used for treating tapeworm, ascariasis, fasciolopsiasis, abdominal pain due to parasitic infestation, dysentery, tenesmus, edema, tinea pedis, and malaria.

Radix angelicae: the source is as follows: dried root of Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook.f. or Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook.f. var. fortusana (Boiss.) Shan et Yuan of Umbelliferae. Nature and taste: pungent and warm. It enters stomach, large intestine and lung meridians. The functional indications are as follows: dispel wind and dampness, induce resuscitation and alleviate pain, resolve swelling and expel pus. Can be used for treating common cold, headache, supraorbital bone pain, nasal obstruction, nasosinusitis, toothache, leucorrhea, and pyocutaneous disease with swelling and pain.

Notopterygium root: the source is as follows: dried rhizome and root of Notopterygium incisum Ting ex H. Chang or Notopterygium forbesii Boiss. Nature and taste: pungent, bitter and warm. It enters bladder and kidney meridians. The functional indications are as follows: dispel cold, expel wind, remove dampness and alleviate pain. Can be used for treating wind-cold type common cold, headache, rheumatalgia, and soreness of shoulder and back.

Radix angelicae pubescentis: the source is as follows: dried root of Angelica gigas nakai of Umbelliferae, Angelica pubescens Maxim. f. biserratha han et Yuan. Nature and taste: pungent, bitter and slightly warm. It enters kidney and bladder meridians. The functional indications are as follows: dispel wind and dampness, relieve arthralgia and alleviate pain. Can be used for treating arthralgia due to wind-cold-dampness, lumbago, gonalgia, and headache due to wind-cold-yin deficiency.

Dried orange peel: the source is as follows: dried mature pericarp of Citrus reticulata Blanco of the Rutaceae family and its cultivars. Nature and taste: bitter, pungent and warm. It enters lung and spleen meridians. The functional indications are as follows: regulate qi to invigorate spleen, dry dampness and resolve phlegm. Can be used for treating fullness in chest and abdomen, anorexia, vomiting, diarrhea, cough, and excessive phlegm.

Wind prevention: the source is as follows: dried roots of Saposhnikoviadivaricata (Turcz.) Schischischk. Nature and taste: pungent, sweet and warm. It enters bladder, liver and spleen meridians. The functional indications are as follows: relieve exterior syndrome, dispel wind, subdue dampness and stop spasm. Can be used for treating common cold, headache, rheumatalgia, rubella, pruritus, and tetanus.

Large-leaved gentian: the source is as follows: dried roots of Gentiana macrophylla pall., Gentiana macrophylla Gentiana pall., Gentiana straminea Maxim, Gentiana macrophylla Gentiana rassicacaulis Duthie ex Burk, or Gentiana miniata Gentiana adhahurica Fisch. Nature and taste: pungent, bitter and mild. It enters stomach, liver and gallbladder meridians. The functional indications are as follows: dispel wind-damp, clear damp-heat, alleviate arthralgia. Can be used for treating rheumatic arthralgia, spasm of tendons and vessels, soreness of bone joints, hectic fever after the day, and infantile malnutrition with fever.

Pawpaw: the source is as follows: dried near-ripe fruit of chaenomeles speciosa (sweet) Nakai of the Rosaceae family. Nature and taste: acid, warm. It enters liver and spleen meridians. The functional indications are as follows: pacify liver, relax tendons, harmonize stomach and resolve dampness. Can be used for treating damp arthralgia, spasm, soreness, pain of waist and knee joint, vomiting, diarrhea, spasm, loempe, and edema.

Eucommia ulmoides: the source is as follows: dried bark of eucommia ulmoides oliv of family eucommia ulmoides. Nature and taste: sweet and warm. It enters liver and kidney meridians. The functional indications are as follows: tonify liver and kidney, strengthen tendons and bones, prevent abortion. Can be used for treating lumbago due to kidney deficiency, weakness of bones and muscles, and pregnant bleeding and threatened abortion; hypertension is caused.

Phellodendron bark: the source is as follows: dried bark of phellodendron chinense or phellodendron amurense rupr of rutaceae. Nature and taste: bitter and cold. It enters kidney, bladder and large intestine meridians. The functional indications are as follows: clear heat and dry dampness, purge fire and remove steam, remove toxicity and cure sore. Can be used for treating leukorrhagia due to damp-heat and heat stranguria; dysentery due to damp-heat, jaundice; syndrome of dampness-heat, beriberi and flaccidity; bone-steaming, fatigue-fever, night sweat, spermatorrhea. Sores, ulcers, swelling, eczema, pruritus and the like.

Achyranthes root: the source is as follows: dried root of achyranthes bidentata blume of Amaranthaceae. Nature and taste: bitter, sour and neutral. It enters liver and kidney meridians. The functional indications are as follows: tonify liver and kidney, strengthen tendons and bones, dispel blood stasis and dredge meridians, and draw blood to descend. Can be used for treating soreness of waist and knees, weakness of tendons and bones, amenorrhea, abdominal mass, and vertigo due to liver-yang.

Dried rehmannia root: the source is as follows: fresh or dried root tuber of rehmannia Rehmanniaglutiosa Libosch. Nature and taste: sweet and cold in nature. It enters heart, liver and kidney meridians. The functional indications are as follows: clear heat and cool blood, nourish yin, promote the production of body fluid. Can be used for treating fever with deep-red tongue, polydipsia, yin deficiency, internal heat, bone steaming, internal heat, diabetes, hematemesis, epistaxis, macula, and eruption.

White peony root: the source is as follows: the product is dried root of Paeonialactarflora pall of Ranunculaceae. Nature and taste: bitter, sour and slightly cold. It enters liver and spleen meridians. The functional indications are as follows: pacify liver and alleviate pain, nourish blood and regulate menstruation, astringe yin and check sweating. Can be used for treating headache, vertigo, hypochondriac pain, abdominal pain, limb spasm and pain, blood deficiency, sallow complexion, menoxenia, spontaneous perspiration, and night sweat. Chinese angelica: the source is as follows: dried root of Diels, Angelica sinensis (Oliv.) Diels, Umbelliferae. Nature and taste: sweet, pungent and warm. It enters liver, heart and spleen meridians. The functional indications are as follows: tonify blood, activate blood, regulate menstruation, alleviate pain, moisten intestines to relieve constipation. Can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, constipation due to intestinal dryness, rheumatic arthralgia, traumatic injury, superficial infection, pyocutaneous disease. The wine angelica sinensis can activate blood and promote menstruation. Can be used for treating amenorrhea, dysmenorrhea, rheumatalgia, and traumatic injury.

Compared with the prior art, the invention has the beneficial effects that:

analysis of the formula:

the application mainly aims at dispelling wind and eliminating dampness, promoting blood circulation and removing blood stasis, tonifying liver and kidney, dredging collaterals and relieving pain and the like. Specifically, the method comprises the following steps: zaocys, lignum Pini nodi, radix Angelicae Pubescentis, Notopterygii rhizoma, radix Saposhnikoviae, radix Gentianae Marcrophyllae, and fructus Chaenomelis can be used for dispelling pathogenic wind, removing dampness, relieving rigidity of muscles, and activating collaterals; carthami flos, rhizoma Ligustici Chuanxiong, radix Angelicae sinensis, Olibanum, Myrrha, and pericarpium Citri Tangerinae for promoting blood circulation, removing blood stasis, promoting qi circulation and relieving pain; cortex Phellodendri, Lumbricus, and radix rehmanniae have effects of clearing heat, promoting blood circulation, removing blood stasis, and dredging collaterals; cortex Eucommiae, fructus Lycii, and radix Achyranthis bidentatae have effects in nourishing liver and kidney, promoting blood circulation, dredging meridians, and strengthening muscle and bone; cortex Cinnamomi warms and unblocks meridians; white peony root, radix Paeoniae alba nourishes blood, astringes yin, soothes liver and relieves pain; eupolyphaga Seu Steleophaga and semen Strychni preparata have repercussive, analgesic, toxic materials removing, and pathogen accumulation dispersing effects; semen plantaginis, radix Angelicae Dahuricae, and Arecae semen have the effects of clearing away heat and promoting diuresis.

When patients are painful, the traditional Chinese medicines for dispelling wind and removing dampness and tonifying liver and kidney are compatible and applied and soaked in white spirit, and when the traditional Chinese medicine is used, a medicinal liquor or an ointment is selected according to the expectation of the patients, and the effect of using the two medicines is better. The ointment of the invention is only needed to be pasted on an affected part, the medicine efficacy is invaded into the pain part through the heat degree of the white spirit, and the medicinal liquor is taken orally, thus achieving the treatment effect.

The traditional Chinese medicine composition for treating rheumatism and rheumatoid arthritis has the advantages of strong efficacy, quick response, high cure rate and small side effect, has the efficacies of dispelling wind and eliminating dampness, promoting blood circulation and removing blood stasis, tonifying liver and kidney, dredging collaterals and relieving pain and the like, and has the efficacy of effectively treating rheumatism and rheumatoid arthritis and low recurrence rate through clinical practice. It is especially suitable for treating femoral head necrosis, rheumatism, rheumatoid diseases, numbness of limbs, and lumbar muscle strain.

The medicinal materials with toxicity of semen Strychni preparata are contraindicated for uremia, heart disease, cerebral thrombosis sequelae and pregnant women.

Detailed Description

The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention,

it is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

The first embodiment is as follows:

a traditional Chinese medicine preparation for treating rheumatic diseases comprises the following components in parts by weight:

20-40g of safflower, 30-50g of honey-fried licorice root, 30-50g of medlar, 40-60g of plantain seed, 3-8g of roasted nux vomica, 10-25g of earthworm, 10-25g of zaocys dhumnade, 10-25g of frankincense, 10-25g of myrrh, 10-25g of ground beetle, 10-25g of Chinese pine node, 10-25g of cinnamon, 30-50g of ligusticum wallichii, 30-50g of betel nut, 30-50g of angelica dahurica, 30-50g of notopterygium root, 30-50g of radix angelicae pubescentis, 20-50g of dried orange peel, 20-50g of divaricate saposhnikovia root, 20-50g of gentiana macrophylla, 20-50g of pawpaw, 20-50g of eucommia bark, 20-50g of phellodendron, 20-50g of achyranthes.

The preparation method of the traditional Chinese medicine wine comprises the following steps:

(1) weighing all the raw material medicaments in parts by weight;

(2) weighing the raw materials in the step (1), crushing and sieving;

The preparation method of the traditional Chinese medicine ointment comprises the following steps:

further, the component A is prepared by the following method:

(3) filtering the mixed solution, and concentrating to obtain extract;

(4) and spreading the extract on gauze to obtain the ointment.

Example two:

a Chinese medicinal preparation for treating rheumatic diseases is prepared from (by weight parts),

30-40g of safflower, 40-50g of honey-fried licorice root, 40-50g of medlar, 50-60g of plantain seed, 5-8g of roasted nux vomica, 15-25g of earthworm, 15-25g of zaocys dhumnade, 15-25g of frankincense, 15-25g of myrrh, 15-25g of ground beetle, 15-25g of Chinese pine node, 15-25g of cinnamon, 40-50g of ligusticum wallichii, 40-50g of betel nut, 40-50g of angelica dahurica, 40-50g of notopterygium root, 40-50g of radix angelicae pubescentis, 35-50g of dried orange peel, 35-50g of divaricate saposhnikovia root, 20-50g of gentiana macrophylla, 20-50g of pawpaw, 20-50g of eucommia bark, 20-50g of phellodendron, 20-50g of achyranthes.

(1) weighing all the raw material medicaments in parts by weight;

(2) weighing the raw materials in the step (1), crushing and sieving;

further, the component A is prepared by the following method:

(3) filtering the mixed solution, and concentrating to obtain extract;

(4) and spreading the extract on gauze to obtain the ointment.

Example three:

40g of safflower, 40g of honey-fried licorice root, 40g of medlar, 55g of plantain seed, 6g of roasted nux vomica, 20g of earthworm, 20g of zaocys dhumnade, 20g of frankincense, 20g of myrrh, 20g of ground beetle, 20g of Chinese pine node, 20g of cinnamon, 400g of ligusticum wallichii, 45g of areca nut, 45g of angelica dahurica, 45g of notopterygium root, 45g of radix angelicae pubescentis, 40g of dried orange peel, 40g of divaricate saposhnikovia root, 40g of large-leaved gentian, 40g of pawpaw, 40g of eucommia bark, 40g of phellodendr.

(1) weighing all the raw material medicaments in parts by weight;

(2) weighing the raw materials in the step (1), crushing and sieving;

further, the component A is prepared by the following method:

(3) filtering the mixed solution, and concentrating to obtain extract;

(4) and spreading the extract on gauze to obtain the ointment.

The technical effect of the invention is further illustrated by combining the test and the specific clinical case:

general data: all 90 cases are patients of rheumatological department in traditional Chinese medicine institute in Wudalianchi city, age is 30-65 years, and course of disease is 6 months-3 years. The groups were randomly divided into 3 groups. The treatment group, the control group 1 and the control group 2 were 30 cases, respectively.

The diagnosis criteria are ① morning stiffness lasting for at least 1 h, the course of disease is at least 6 weeks, ② symmetric joint swelling for at least 6 weeks, ③ 3 or more than 3 joints swelling for at least 6 weeks, ④ wrist joint or metacarpophalangeal joint or proximal phalangeal joint swelling for at least 6 weeks, ⑤ subcutaneous rheumatoid nodules, ⑥ rheumatoid factor positivity (titer > 1: 32), ⑦ hand X-ray disc changes (at least osteoporosis and joint space stenosis), and the patients meeting 4 of the above criteria can be diagnosed.

The treatment method comprises the following steps: the 3 groups are orally taken by ibuprofen sustained-release capsules 1.2 g/d for 3 times, and methotrexate tablets 7.5 mg/week are orally taken for 1 d. The treatment group 1 took the medicinal liquor of the invention at the same time without adopting an external plaster, and the treatment group 2 took the medicinal liquor of the invention and the external plaster at the same time.

3 groups are treated for 1 course of treatment, and 30 days is one course of treatment.

Evaluating the curative effect: during the treatment period, the patient is advised to avoid wind cold and pay attention to rest.

The evaluation standard of curative effect is as follows:

the effect is shown: morning stiffness, fatigue and joint pain disappear, joint swelling is obviously improved, rheumatoid factors turn negative, erythrocyte sedimentation rate and C-reactive protein are normal.

The method has the following advantages: morning stiffness, fatigue and joint pain are obviously relieved, joint swelling is improved, and rheumatoid factors, erythrocyte sedimentation rate and C-reactive protein are obviously improved.

And (4) invalidation: the disease condition is not obviously relieved; or not alleviated; the improvement of rheumatoid factor, blood sedimentation and C-reactive protein is not obvious or is not improved.

Table 13 shows comparative efficacy (example,%)

Group of	n	Show effect	Is effective	Invalidation	Total effective rate
						Treatment group	30	14	8	8	73.33%
Control group 1	30	16	9	5	83.33%
						Control group 2	30	19	8	3	90.00%

The total effective rates of the treatment groups 1 and 2 are 83.33 percent and 90 percent respectively, which are obviously higher than 73.33 percent of the control group (P is less than 0.05), and especially, the traditional Chinese medicine preparation of the invention has better effect when being taken orally and applied externally.

The first clinical case is:

zhang-a, female, age 45, home in Wudalianchi city to build countryside, home-grown rice, cold weather in the early spring, frequent paddy field, leg pain, swelling and numbness caused by wind-cold, and leg pain aggravation in cold weather, and diagnosis of rheumatic disease. After the medicinal liquor is taken and the plaster is externally applied, the pain is relieved after one week, the feeling effect is good, after the plaster is continuously taken for 1 month, the pain, swelling, numbness and other symptoms of a patient are relieved, and after the medicinal liquor is continuously taken for 3 months, the symptoms completely disappear, and the dry farm life in a paddy field is not recurred.

The second clinical case:

in Liji, male, 45 years old, living in Wudalianchi city, the knee joint is red, swollen and painful two years ago, the joint is stiff, the squatting is difficult, and the cold and wet weather symptoms are more serious. The rheumatism arthritis is diagnosed when the patient visits the local hospital. Since no alcohol is drunk at ordinary times, the plaster of the invention is selected for use. After being pasted for 3 days, the symptoms are obviously relieved. The joint is continuously used after the patient keeps on, the red swelling and pain of the joint disappear, and the patient can freely squat.

The third clinical case:

wangzhi, female, 65 years old, living in Taiping countryside in Wudalianchi city, suffered from postpartum cold in young, appeared in large joints, often suffered from pain, difficulty in flexion and extension, stiffness and numbness, suffered from rheumatic arthritis, and had changed hand joints of X-ray films. The subsequent work and life are always influenced, and a plurality of western medicines are taken orally and only relieved. After the traditional Chinese medicine preparation is taken, the traditional Chinese medicine preparation is taken orally and externally, the hand joints are not painful, the bending and stretching are not good, and the symptoms of stiffness and numbness disappear gradually.

Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims

1. A traditional Chinese medicine preparation for treating rheumatism and rheumatoid arthritis comprises the following components in parts by weight: comprises 20-40 parts of safflower, 30-50 parts of honey-fried licorice root, 30-50 parts of medlar, 40-60 parts of plantain seed, 3-8 parts of roasted nux vomica, 10-25 parts of earthworm, 10-25 parts of zaocys dhumnade, 10-25 parts of frankincense, 10-25 parts of myrrh, 10-25 parts of ground beetle, 10-25 parts of Chinese pine node, 10-25 parts of cinnamon, 30-50 parts of ligusticum wallichii, 30-50 parts of areca seed, 30-50 parts of angelica dahurica, 30-50 parts of notopterygium root, 30-50 parts of radix angelicae pubescentis, 20-50 parts of dried orange peel, 20-50 parts of divaricate saposhnikovia root, 20-50 parts of large-leaved gentian, 20-50 parts of.

2. The traditional Chinese medicine preparation of claim 1, which comprises the following components in parts by weight: comprises 30-40 parts of safflower, 40-50 parts of honey-fried licorice root, 40-50 parts of medlar, 50-60 parts of plantain seed, 5-8 parts of roasted nux vomica, 15-25 parts of earthworm, 15-25 parts of zaocys dhumnade, 15-25 parts of frankincense, 15-25 parts of myrrh, 15-25 parts of ground beetle, 15-25 parts of Chinese pine knot, 15-25 parts of cinnamon, 40-50 parts of ligusticum wallichii, 40-50 parts of betel nut, 40-50 parts of angelica dahurica, 40-50 parts of notopterygium root, 40-50 parts of radix angelicae pubescentis, 35-50 parts of dried orange peel, 35-50 parts of divaricate saposhnikovia root, 20-50 parts of large-leaved gentian, 20-50 parts.

3. The traditional Chinese medicine preparation of claim 1, which comprises the following components in parts by weight: comprises safflower 40, honey-fried licorice root 40, medlar 40, plantain seed 55, roasted nux vomica 6, earthworm 20, zaocys dhumnade 20, frankincense 20, myrrh 20, ground beetle 20, Chinese pine knot 20, cinnamon 20, hemlock parsley 400, areca 45, angelica dahurica 45, notopterygium 45, pubescent angelica root 45, dried orange peel 40, divaricate saposhnikovia root 40, large-leaved gentian 40, pawpaw 40, eucommia bark 40, phellodendron bark 40, achyranthes root 40, dried rehmannia root 40, white paeony root 40 and angelica 40.

4. A preparation method of a traditional Chinese medicine wine comprises the following steps:

(1) weighing the raw material medicament of claim 1 in parts by weight;

(2) weighing the raw materials in the step (1), crushing and sieving;

(3) adding 10-15 times of 30-50 degrees of pure grain liquor according to the weight parts, and fully soaking the crushed raw material medicines for about 24 hours to obtain the medicinal liquor.

5. The method of preparing a medicated wine of claim 4, comprising the steps of:

(2) putting the powder prepared in the step (1) into pure sorghum liquor with the alcohol content of about 35-50 degrees, and soaking for 20-30 days to obtain a mixed solution;

(3) filtering the mixed solution, and concentrating to obtain extract;

(4) and spreading the extract on gauze to obtain the ointment.

6. The Chinese medicated liquor of claim 4, optionally comprising flavoring agents such as Mel and fructose.