CN110809627A - 用于xla基因疗法的优化的慢病毒载体 - Google Patents
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/46—Vector systems having a special element relevant for transcription elements influencing chromatin structure, e.g. scaffold/matrix attachment region, methylation free island
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762488523P | 2017-04-21 | 2017-04-21 | |
| US62/488,523 | 2017-04-21 | ||
| PCT/US2018/028331 WO2018195297A1 (en) | 2017-04-21 | 2018-04-19 | Optimized lentiviral vector for xla gene therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110809627A true CN110809627A (zh) | 2020-02-18 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880043435.0A Pending CN110809627A (zh) | 2017-04-21 | 2018-04-19 | 用于xla基因疗法的优化的慢病毒载体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20200325458A1 (enIt.pdf) |
| EP (1) | EP3612238A4 (enIt.pdf) |
| JP (2) | JP7471821B2 (enIt.pdf) |
| CN (1) | CN110809627A (enIt.pdf) |
| AU (1) | AU2018256412A1 (enIt.pdf) |
| WO (1) | WO2018195297A1 (enIt.pdf) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3109924A1 (en) | 2018-08-24 | 2020-02-27 | Csl Behring Gene Therapy, Inc. | Vector production in serum free media |
| US11464872B2 (en) | 2020-12-07 | 2022-10-11 | Noga Therapeutics Ltd. | Lentiviral vectors for therapeutic expression of BTK in haematopoietic cells |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US6974667B2 (en) * | 2000-06-14 | 2005-12-13 | Gene Logic, Inc. | Gene expression profiles in liver cancer |
| US20160004814A1 (en) * | 2012-09-05 | 2016-01-07 | University Of Washington Through Its Center For Commercialization | Methods and compositions related to regulation of nucleic acids |
-
2018
- 2018-04-19 AU AU2018256412A patent/AU2018256412A1/en active Pending
- 2018-04-19 JP JP2019557373A patent/JP7471821B2/ja active Active
- 2018-04-19 US US16/605,740 patent/US20200325458A1/en active Pending
- 2018-04-19 CN CN201880043435.0A patent/CN110809627A/zh active Pending
- 2018-04-19 WO PCT/US2018/028331 patent/WO2018195297A1/en active Application Filing
- 2018-04-19 EP EP18788504.1A patent/EP3612238A4/en active Pending
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2024
- 2024-04-10 JP JP2024063151A patent/JP2024084849A/ja active Pending
Non-Patent Citations (3)
| Title |
|---|
| HANNAH KERNS等: "Lentiviral Vectors Using a Ubiquitously Acting Chromatin Opening Element and Endogenous Btk Promoter Restore B and Myeloid Cell Defects in Murine X-Linked Agammaglobulinemia", 《MOLECULAR THERAPY》 * |
| HANNAH M. KERNS等: "B cell–specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia", 《BLOOD》 * |
| SWATI SINGH等: "BTK-Promoter LV Vectors Utilizing Conserved Intron Element Mediate Functional Rescue in Murine XLA", 《MOLECULAR THERAPY》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3612238A4 (en) | 2020-12-30 |
| JP7471821B2 (ja) | 2024-04-22 |
| JP2024084849A (ja) | 2024-06-25 |
| EP3612238A1 (en) | 2020-02-26 |
| AU2018256412A1 (en) | 2019-11-07 |
| JP2020517268A (ja) | 2020-06-18 |
| US20200325458A1 (en) | 2020-10-15 |
| WO2018195297A1 (en) | 2018-10-25 |
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