CN110680553A - Adjustable operation panel suitable for rat brain stereotaxic apparatus - Google Patents
Adjustable operation panel suitable for rat brain stereotaxic apparatus Download PDFInfo
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- CN110680553A CN110680553A CN201911115244.3A CN201911115244A CN110680553A CN 110680553 A CN110680553 A CN 110680553A CN 201911115244 A CN201911115244 A CN 201911115244A CN 110680553 A CN110680553 A CN 110680553A
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- 210000004556 brain Anatomy 0.000 title claims abstract description 37
- 230000007246 mechanism Effects 0.000 claims abstract description 58
- 238000010241 blood sampling Methods 0.000 abstract description 4
- 241000700159 Rattus Species 0.000 description 57
- 241000699666 Mus <mouse, genus> Species 0.000 description 30
- 238000002474 experimental method Methods 0.000 description 13
- 238000000034 method Methods 0.000 description 11
- 230000008569 process Effects 0.000 description 11
- 241000699670 Mus sp. Species 0.000 description 8
- 238000003780 insertion Methods 0.000 description 6
- 230000037431 insertion Effects 0.000 description 6
- 210000005036 nerve Anatomy 0.000 description 5
- 238000011160 research Methods 0.000 description 5
- 230000000452 restraining effect Effects 0.000 description 4
- 238000010171 animal model Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 201000006474 Brain Ischemia Diseases 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 206010008120 Cerebral ischaemia Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000018737 Parkinson disease Diseases 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 230000003028 elevating effect Effects 0.000 description 1
- 238000011705 epilepsy animal model Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000001178 neural stem cell Anatomy 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 238000011476 stem cell transplantation Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/003—Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/006—Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
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- Engineering & Computer Science (AREA)
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- Animal Behavior & Ethology (AREA)
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Abstract
The invention provides an adjustable operating platform suitable for a rat brain stereotaxic apparatus, which comprises a first operating platform, a second operating platform, a bottom plate, a first lifting mechanism and a second lifting mechanism, wherein the first operating platform is arranged on the first operating platform; the first operating platform and the second operating platform are correspondingly arranged above the bottom plate, the first lifting mechanism is connected between the first operating platform and the bottom plate, and the second lifting mechanism is connected between the second operating platform and the bottom plate; the first lifting mechanism comprises a first driving rod, a first driven rod and a first adjusting knob, and the second lifting mechanism comprises a second driving rod, a second driven rod and a second adjusting knob. Preferably, a longitudinal adjusting mechanism and a transverse adjusting mechanism are further included. The invention can be adjusted in 3 degrees of freedom, and the operator can operate the mouse in one person, so that the positioning of the rat or the mouse is more convenient, and the manpower is saved; the tail fixing frame is arranged, so that an operator can conveniently carry out tail blood sampling operation.
Description
Technical Field
The invention relates to the technical field of medical research and medical equipment, in particular to an adjustable operating platform suitable for a rat brain stereotaxic apparatus.
Background
The brain stereotaxic apparatus is also called a brain fixing apparatus (english name: stereotaxic apparatus), which uses a three-dimensional coordinate system defined by a mark or other reference point outside the skull to determine the position of some nerve structures under the cortex, so as to perform directional stimulation, destruction, drug injection, electric potential guidance and other researches on the nerve structures under the condition of non-direct-view exposure. The animal brain stereotaxic apparatus is important research equipment in the fields of nerve anatomy, nerve physiology, neuropharmacology, neurosurgery and the like, is used for performing directional injection, stimulation, damage, electric potential guidance and other operations on a nerve structure, and can be used for the researches of cerebral hemorrhage animal model establishment, Parkinson's disease animal model establishment, epilepsy animal model establishment, intracerebral tumor model establishment, learning and memory, intracerebral neural stem cell transplantation, cerebral ischemia and the like.
At present, the commonly used brain stereotaxic instruments for rats and mice are generally provided with a portal hook and ear rods at two sides, the portal teeth of the rats and the mice are fixed on the portal hook, the ear rods at the two sides are aligned to the auditory canals of the rats and the mice, and the heads of the rats and the mice are fixed by utilizing a three-point positioning principle, so that the follow-up research is facilitated; however, when the brain stereotaxic apparatus is used for positioning rats and mice at present, the following defects exist:
(1) when the rat and the mouse are fixed, two persons are needed to cooperate, one person holds the bodies of the rat and the mouse to adjust the height and the position, and the ear rod is adjusted by one person to align with the auditory canals of the rat and the mouse, so that the operation is troublesome, and redundant manpower is consumed;
(2) the existing fixing mode is only that two ears and a mouth are fixed, the whole body is not fixed or is suspended, and the fixing looseness can be caused in the experiment process to influence the experiment process;
(3) when tail blood sampling operation is performed on rats and mice, although the rats and the mice are in an anaesthetized state, the tails of the rats and the mice are tough and easy to move, and blood sampling is inconvenient.
Disclosure of Invention
The invention aims to solve the defects in the prior art, and provides an adjustable operating platform suitable for a rat brain stereotaxic apparatus, which is labor-saving and convenient to operate.
In order to achieve the purpose, the invention adopts the following technical scheme:
an adjustable operating platform suitable for a rat/mouse brain stereotaxic apparatus comprises a first operating platform, a second operating platform, a bottom plate, a first lifting mechanism and a second lifting mechanism; the first operating platform and the second operating platform are correspondingly arranged above the bottom plate, the first lifting mechanism is connected between the first operating platform and the bottom plate, and the second lifting mechanism is connected between the second operating platform and the bottom plate.
The first lifting mechanism comprises a first driving rod, a first driven rod and a first adjusting knob, the middle part of the first driving rod is hinged with the middle part of the first driven rod, the first driving rod and the first driven rod are in an X shape, the upper end of the first driving rod is hinged to the side edge of the first operating platform, the lower end of the first driving rod is hinged to the side edge of the bottom plate, and the first adjusting knob is fixed to the outer side of the lower end of the first driving rod; the side of the first operating platform is provided with a first sliding groove, the side of the bottom plate is correspondingly provided with a second sliding groove, the upper end of the first driven rod is embedded into the first sliding groove, and the lower end of the first driven rod is embedded into the second sliding groove.
The width direction of the bottom plate is used as the X direction, the length direction of the bottom plate is used as the Y direction, the X direction and the Y direction are perpendicular to each other, and the extending direction of the first sliding groove and the extending direction of the second sliding groove are parallel to the Y direction.
Preferably, the second lifting mechanism comprises a second driving rod, a second driven rod and a second adjusting knob, the middle part of the second driving rod is hinged to the middle part of the second driven rod, the second driving rod and the second driven rod are in an X shape, the upper end of the second driving rod is hinged to the side edge of the second operating platform, the lower end of the second driving rod is hinged to the side edge of the bottom plate, and the second adjusting knob is fixed to the outer side of the lower end of the second driving rod; the side of the second operation platform is provided with a third sliding groove, the side of the bottom plate is correspondingly provided with a fourth sliding groove, the upper end of the second driven rod is correspondingly embedded into the third sliding groove, and the lower end of the second driven rod is correspondingly embedded into the fourth sliding groove.
Preferably, the adjusting mechanism comprises a longitudinal adjusting mechanism, the longitudinal adjusting mechanism comprises a first base, the first base is parallel to the bottom plate, a first guide rail is arranged on the first base along the Y direction, a first sliding block is arranged on the first guide rail, the top surface of the first sliding block is fixedly connected with the bottom surface of the bottom plate, a first adjusting rod is connected to the side edge of the first sliding block, and the first adjusting rod is arranged along the X direction.
Preferably, the adjusting device comprises a transverse adjusting mechanism, the transverse adjusting mechanism comprises a second base, the second base is parallel to the bottom plate, a second guide rail is arranged on the second base along the X direction, a second sliding block is arranged on the second guide rail, the top surface of the second sliding block is fixedly connected with the bottom surface of the first base, a second adjusting rod is connected to the side edge of the second sliding block, and the second adjusting rod is arranged along the Y direction.
Preferably, the bottom surface of the second base is provided with an anti-slip groove.
Preferably, be equipped with the trunk fixed slot on the first operation panel, be equipped with the head fixed slot on the second operation panel, set up four limbs restraint band and the restraint band of trunk on the first operation panel, the both ends of the restraint band of trunk are connected respectively the both sides of trunk fixed slot.
Preferably, one side that first operation panel kept away from the second operation panel is equipped with the afterbody mount, the afterbody mount is the loudspeaker form, just the inner opening of afterbody mount is big, the outer end opening is little.
Preferably, the tail fixing frame comprises an upper half part and a lower half part, the upper half part is hinged with one side of the lower half part, and the other side of the upper half part is detachably connected with the other side of the lower half part through a fastening bolt.
Preferably, a first embedded block is arranged at the upper end of the first driven rod, and the structure of the first embedded block is matched with that of the first sliding chute; and a second embedded block is arranged at the lower end of the first driven rod, and the structure of the second embedded block is matched with that of the second sliding groove.
Preferably, a third embedded block is arranged at the upper end of the second driven rod, and the structure of the third embedded block is matched with that of the third sliding chute; and a fourth embedded block is arranged at the lower end of the second driven rod, and the structure of the fourth embedded block is matched with that of the fourth sliding groove.
Compared with the prior art, the invention has the beneficial effects that:
(1) during the experiment, the trunk of the anesthetized rat or mouse is placed on the first operating platform, the head of the anesthetized rat or mouse is placed on the second operating platform, the first lifting mechanism is used for adjusting the height of the first operating platform, the second lifting mechanism is used for adjusting the height of the second operating platform, the positioning operation can be completed by only one person, and the labor is saved;
(2) the heights of the first operating platform and the second operating platform can be independently adjusted, namely the positions of the trunk or the head of a rat or a mouse can be independently adjusted within an allowable range, and the adjustment flexibility is strong;
(3) the first operating platform is provided with a trunk fixing groove, four-limb restraining belts and a trunk restraining belt, the second operating platform is provided with a head fixing groove, the trunk and the head of a rat or a mouse can be fixed respectively, the rat or the mouse is prevented from loosening in the experiment process, and the smooth experiment process is facilitated;
(4) a longitudinal adjusting mechanism and a transverse adjusting mechanism are further arranged below the bottom plate, so that the horizontal positions of the first operating platform and the second operating platform can be conveniently adjusted, and the operation can be carried out by only one person, so that the positioning operation is more accurate, and the labor is saved;
(5) the tail fixing frame with the large inner end opening and the small outer end opening is arranged on the first operating platform, the tail of a rat or a mouse is effectively fixed by the tail fixing frame, the tail of the rat or the mouse is prevented from moving disorderly, and tail blood taking operation in the experimental process is facilitated.
Drawings
Fig. 1 is a perspective view of an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention;
fig. 2 is a split perspective view of an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 2 of the present invention;
fig. 3 is a perspective view of a first lifting mechanism in an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention;
fig. 4 is a perspective view of a second lifting mechanism in an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention;
fig. 5 is a side view of the position of a first driven rod in an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention;
fig. 6 is a side view of the second driven rod of the adjustable operating platform suitable for the rat brain stereotaxic apparatus in embodiment 1 of the present invention;
fig. 7 is a perspective view of a tail fixing frame in an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention.
Wherein, 10-a first operation platform, 11-a first sliding chute, 12-a trunk fixing chute, 13-a four limbs restraint belt, 14-a trunk restraint belt, 15-a tail fixing frame, 151-an upper half part, 152-a lower half part, 153-a fastening bolt, 20-a second operation platform, 21-a third sliding chute, 22-a head fixing chute, 30-a bottom plate, 31-a second sliding chute, 32-a fourth sliding chute, 40-a first lifting mechanism, 4-a first driving rod, 42-a first driven rod, 421-a first embedded block, 422-a second embedded block, 43-a first adjusting knob, 44-a first cross rod, 50-a second lifting mechanism, 51-a second driving rod, 52-a second rod, 521-a third embedded block and 522-a fourth embedded block, 53-a second adjusting knob, 54-a second cross bar, 60-a longitudinal adjusting mechanism, 61-a first base, 62-a first guide rail, 63-a first sliding block, 64-a first adjusting bar, 70-a transverse adjusting mechanism, 71-a second base, 711-an anti-skidding groove, 72-a second guide rail, 73-a second sliding block, and 74-a second adjusting bar.
Detailed Description
In order to further understand the objects, structures, features and functions of the present invention, the following embodiments are described in detail.
Referring to fig. 1 to 7 in combination, fig. 1 is a perspective view of an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention; fig. 2 is a split perspective view of an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 2 of the present invention; fig. 3 is a perspective view of a first lifting mechanism in an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention; fig. 4 is a perspective view of a second lifting mechanism in an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention; fig. 5 is a side view of the position of a first driven rod in an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention; fig. 6 is a side view of the second driven rod of the adjustable operating platform suitable for the rat brain stereotaxic apparatus in embodiment 1 of the present invention; fig. 7 is a perspective view of a tail fixing frame in an adjustable operating platform suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention.
Referring to fig. 1, an adjustable console suitable for a rat brain stereotaxic apparatus according to embodiment 1 of the present invention includes a first console 10, a second console 20, a bottom plate 30, a first lifting mechanism 40, and a second lifting mechanism 50; the first and second tables 10 and 20 are disposed above the base plate 30, respectively, and the first and second elevating mechanisms 40 and 50 are connected between the first and second tables 10 and 30 and between the base plate 30 and the second table 20, respectively. During the experiment, the trunk of the anesthetized rat or mouse is placed on the first operating platform 10, the head of the anesthetized rat or mouse is placed on the second operating platform 20, the first lifting mechanism 40 is used for adjusting the height of the first operating platform 10, the second lifting mechanism 50 is used for adjusting the height of the second operating platform 20, and the positioning operation can be completed by only one person, so that the labor is saved; the heights of the first operating platform 10 and the second operating platform 20 can be independently adjusted, namely the position of the trunk or the head of a rat or a mouse can be independently adjusted within an allowable range, and the adjustment flexibility is strong.
Referring to fig. 1, 3 and 5, the first lifting mechanism 40 includes a first driving rod 41, a first driven rod 42 and a first adjusting knob 43, the middle of the first driving rod 41 is hinged to the middle of the first driven rod 42, the first driving rod 41 and the first driven rod 42 are in an X shape, the upper end of the first driving rod 41 is hinged to the side of the first console 10, the lower end of the first driving rod 41 is hinged to the side of the bottom plate 30, and the first adjusting knob 43 is fixed to the outer side of the lower end of the first driving rod 41; the first operating platform 10 is provided with a first sliding groove 11 at a side edge, the bottom plate 30 is correspondingly provided with a second sliding groove 31 at a side edge, an upper end of the first driven rod 42 is embedded in the first sliding groove 11, a lower end of the first driven rod 42 is embedded in the second sliding groove 31, the upper end of the first driven rod 42 can slide in the first sliding groove 11, and the lower end of the first driven rod 42 can slide in the second sliding groove 31. The height adjustment process of the first operation table 10 is as follows: when the first adjusting knob 43 is rotated, the first driving rod 41 rotates, the angle between the first driving rod 41 and the bottom plate 30 changes, and because the first driven rod 42 is hinged to the first driving rod 41, the upper end of the first driven rod 42 can slide in the first sliding chute 11, and the lower end of the first driven rod 42 can slide in the second sliding chute 31, the first driven rod 42 also rotates at the same time, the angle between the first driven rod 42 and the bottom plate 30 changes, so that the height between the first operating platform 10 and the bottom plate 30 is changed, and the purpose of height adjustment is achieved; in embodiment 1 of the present invention, the height of the first console 10 can be adjusted lower by rotating the first adjustment knob 43 clockwise, and the height of the first console 10 can be adjusted higher by rotating the first adjustment knob 43 counterclockwise.
The extending direction of the first chute 11 and the extending direction of the second chute 31 are parallel to the Y direction, with the width direction of the base plate 30 being the X direction, the length direction of the base plate 30 being the Y direction, and the direction perpendicular to the X direction and the Y direction being the Z direction.
Preferably, referring to fig. 1, 4 and 6 in combination, the second lifting mechanism 50 includes a second driving rod 51, a second driven rod 52 and a second adjusting knob 53, the middle of the second driving rod 51 is hinged to the middle of the second driven rod 52, the second driving rod 51 and the second driven rod 52 are in an X shape, the upper end of the second driving rod 51 is hinged to the side of the second console 20, the lower end of the second driving rod 51 is hinged to the side of the bottom plate 30, and the second adjusting knob 53 is fixed to the outer side of the lower end of the second driving rod 51; the second operating platform 20 is provided with a third sliding slot 21 at a side edge, the bottom plate 30 is correspondingly provided with a fourth sliding slot 32 at a side edge, the upper end of the second driven rod 52 is correspondingly embedded in the third sliding slot 21, the lower end of the second driven rod 52 is correspondingly embedded in the fourth sliding slot 32, the upper end of the second driven rod 52 can slide in the third sliding slot 21, and the lower end of the second driven rod 52 can slide in the fourth sliding slot 32. The height adjustment process of the second station 20 is similar to the height adjustment process of the first station 10: when the second adjusting knob 53 is rotated, the second driving rod 51 rotates, the angle between the second driving rod 51 and the bottom plate 30 changes, and since the second driven rod 52 is hinged to the second driving rod 51, the upper end of the second driven rod 52 can slide in the third sliding chute 21, and the lower end of the second driven rod 52 can slide in the fourth sliding chute 32, the second driven rod 52 also rotates, the angle between the second driven rod 52 and the bottom plate 30 changes, so that the height between the second operating platform 20 and the bottom plate 30 is changed, and the purpose of height adjustment is achieved; in embodiment 1 of the present invention, the height of the second console 20 can be adjusted downward by rotating the second adjustment knob 53 clockwise, and the height of the second console 20 can be adjusted upward by rotating the second adjustment knob 53 counterclockwise.
Referring to fig. 3, in a preferred embodiment of the present invention, the first operating platform 10 is provided with a first driving rod 41 and a first driven rod 42 at two sides thereof, and a first cross rod 44 is hinged in the middle thereof, so as to enhance the stability of the first operating platform 10; referring to fig. 4, in the preferred embodiment of the present invention, the second driving rod 51 and the second driven rod 52 are respectively disposed at two sides of the second operating platform 20, and the second cross bar 54 is hinged in the middle, so as to enhance the stability of the second operating platform 20.
Preferably, referring to fig. 2, the adjustable operating platform according to embodiment 2 of the present invention further includes a longitudinal adjusting mechanism 60, the longitudinal adjusting mechanism 60 includes a first base 61, the first base 61 is parallel to the bottom plate 30, a first guide rail 62 is disposed on the first base 61 along the Y direction, a first sliding block 63 is disposed on the first guide rail 62, a top surface of the first sliding block 63 is fixedly connected to a bottom surface of the bottom plate 30, a side edge of the first sliding block 63 is connected to a first adjusting rod 64, and the first adjusting rod 64 is disposed along the X direction. In the present invention, the longitudinal adjustment mechanism 60 is used to adjust the Y-direction positions of the first and second operation tables 10 and 20, and when the first adjustment lever 64 is pulled, the first slider 63 slides along the first guide rail 62.
Preferably, referring to fig. 2, the adjustable operating platform according to embodiment 2 of the present invention further includes a horizontal adjusting mechanism 70, the horizontal adjusting mechanism 70 includes a second base 71, the second base 71 is parallel to the bottom plate 30, a second guide rail 72 is disposed on the second base 71 along the X direction, a second slider 73 is disposed on the second guide rail 72, a top surface of the second slider 73 is fixedly connected to a bottom surface of the first base 61, a side edge of the second slider 73 is connected to a second adjusting rod 74, and the second adjusting rod 74 is disposed along the Y direction. In the present invention, the position in the X direction of the first and second tables 10 and 20 is adjusted by the lateral adjustment mechanism 70, and when the second adjustment lever 74 is pulled, the second slider 73 slides along the second guide rail 72.
Preferably, referring to fig. 2, the bottom surface of the second base 71 is provided with an anti-slip groove 711, which can increase the friction force between the bottom surface of the second base 71 and the experiment table, ensure the stability of the present invention, and prevent the second base from slipping.
Preferably, referring to fig. 1 or fig. 2, a trunk fixing groove 12 is formed on the first operating platform 10, a head fixing groove 22 is formed on the second operating platform 20, a limb restraint strap 13 and a trunk restraint strap 14 are formed on the first operating platform 10, and two ends of the trunk restraint strap 14 are respectively connected to two sides of the trunk fixing groove 12. During the experiment, the trunk part of the rat or the mouse after anesthesia is arranged in the trunk fixing groove 12, the head part is arranged in the head fixing groove 22, the four limbs of the rat or the mouse are fixed by the four limb restraint belts 13, and the trunk of the rat or the mouse is fixed by the trunk restraint belts 14, so that the rat or the mouse is prevented from sliding in the experiment process, and the experiment result is prevented from being influenced. Preferably, one end of the trunk restraint strap 14 is fixedly connected to the first console 10, and the other end is detachably connected to the first console 10 using a hook and loop fastener or the like.
Preferably, referring to fig. 1 and fig. 7, in a preferred embodiment of the present invention, a tail fixing frame 15 is disposed on a side of the first operating platform 10 away from the second operating platform 20, the tail fixing frame 15 is in a horn shape, and an inner end opening of the tail fixing frame 15 is large and an outer end opening thereof is small. The tail fixing frame 15 can fix the tail of a rat or a mouse, so that the tail of the rat or the mouse is prevented from moving around due to toughness, and a researcher can conveniently carry out tail blood sampling operation on the tail of the rat or the mouse. Preferably, the rear mount 15 includes an upper half 151 and a lower half 152, and the upper half 151 is hinged to one side of the lower half 152 and the other side is detachably coupled by a fastening bolt 153. The lower half part 152 of the tail fixing frame 15 is fixed on the first operating platform 10, the upper half part 151 can rotate around the hinged position of the lower half part 152, when a rat or a mouse is fixed, the upper half part 151 is opened, the tail of the rat or the mouse is placed in the lower half part 152, the upper half part 151 is covered, and the upper half part 151 and the lower half part 152 are fixedly connected through the fastening bolt 153, so that the tail of the rat or the mouse can be effectively fixed, and the subsequent operation is convenient.
Preferably, referring to fig. 3 or 5, the upper end of the first driven rod 42 is provided with a first insertion block 421, the structure of the first insertion block 421 matches with the structure of the first sliding chute 11, and the first insertion block 421 is inserted into the first sliding chute 11 and can slide in the first sliding chute 11; the lower end of the first driven rod 42 is provided with a second embedded block 422, the structure of the second embedded block 422 is matched with the structure of the second sliding chute 31, and the second embedded block 422 is embedded in the second sliding chute 31 and can slide in the second sliding chute 31; when the first driving rod 41 is rotated by using the first adjusting knob 43, the first driven rod 42 is hinged to the first driving rod 41, so that the first driven rod 42 can be driven to rotate, the first embedded block 421 slides in the first sliding groove 11, the second embedded block 422 slides in the second sliding groove 31, the distance between the first operating platform 10 and the bottom plate 30 is further changed, and the purpose of adjusting the height of the first operating platform 10 is achieved; in embodiment 1, the height of the first console 10 can be adjusted downward by rotating the first adjustment knob 43 clockwise, and the height of the first console 10 can be adjusted upward by rotating the first adjustment knob 43 counterclockwise.
Referring to fig. 4 or 6, a third insertion block 521 is disposed at an upper end of the second driven rod 52, a structure of the third insertion block 521 matches a structure of the third sliding chute 21, and the third insertion block 521 is inserted into the third sliding chute 21 and can slide in the third sliding chute 21; the lower end of the second driven rod 52 is provided with a fourth embedded block 522, the structure of the fourth embedded block 522 is matched with the structure of the fourth sliding chute 32, and the fourth embedded block 522 is embedded in the fourth sliding chute 32 and can slide in the fourth sliding chute 32; when the second driving rod 51 is rotated by using the second adjusting knob 53, the second driven rod 52 is hinged to the second driving rod 51, so that the second driven rod 52 can be driven to rotate, the third embedded block 521 slides in the third sliding groove 21, the fourth embedded block 522 slides in the fourth sliding groove 32, the distance between the second operating platform 20 and the bottom plate 30 is further changed, and the purpose of adjusting the height of the second operating platform 20 is achieved; in embodiment 1, the height of the second console 20 can be adjusted downward by rotating the second adjustment knob 53 clockwise, and the height of the second console 20 can be adjusted upward by rotating the second adjustment knob 53 counterclockwise.
In conclusion, the invention provides an adjustable operating platform suitable for a rat brain stereotaxic apparatus, during experiments, the trunk of an anesthetized rat or mouse is placed on a first operating platform 10, the head of the anesthetized rat or mouse is placed on a second operating platform 20, the first lifting mechanism 40 is used for adjusting the height of the first operating platform 10, the second lifting mechanism 50 is used for adjusting the height of the second operating platform 20, and only one person is needed to complete positioning operation, so that manpower is saved; the heights of the first operating platform 10 and the second operating platform 20 can be independently adjusted, namely the positions of the trunk or the head of a rat or a mouse can be independently adjusted within an allowable range, and the adjustment flexibility is strong; the first operating platform 10 is provided with a trunk fixing groove 12, four-limb restraining belts 13 and a trunk restraining belt 14, the second operating platform 20 is provided with a head fixing groove 22, the trunk and the head of a rat or a mouse can be fixed respectively, the rat or the mouse is prevented from loosening in the experiment process, and the smooth operation of the experiment process is facilitated; preferably, a longitudinal adjusting mechanism 60 and a transverse adjusting mechanism 70 are further arranged below the bottom plate 30, so that the horizontal positions of the first operating platform 10 and the second operating platform 20 can be conveniently adjusted, and only one person is needed to operate, so that the positioning operation is more accurate, and the labor is saved; set up afterbody mount 15 that the inner end opening is little, the outer end opening is big on first operation panel 10, utilize afterbody mount 15 to carry out effective fixed to the afterbody of rat, mouse, avoid its afterbody to move about with others, make things convenient for the afterbody operation of getting blood in the experimentation.
The present invention has been described in relation to the above embodiments, which are only exemplary of the implementation of the present invention. It should be noted that the disclosed embodiments do not limit the scope of the invention. Rather, it is intended that all such modifications and variations be included within the spirit and scope of this invention.
Claims (10)
1. The utility model provides an operation panel with adjustable be applicable to big mouse brain stereotaxic appearance which characterized in that: the device comprises a first operating platform, a second operating platform, a bottom plate, a first lifting mechanism and a second lifting mechanism; the first operating platform and the second operating platform are correspondingly arranged above the bottom plate, the first lifting mechanism is connected between the first operating platform and the bottom plate, and the second lifting mechanism is connected between the second operating platform and the bottom plate;
the first lifting mechanism comprises a first driving rod, a first driven rod and a first adjusting knob, the middle part of the first driving rod is hinged with the middle part of the first driven rod, the first driving rod and the first driven rod are in an X shape, the upper end of the first driving rod is hinged to the side edge of the first operating platform, the lower end of the first driving rod is hinged to the side edge of the bottom plate, and the first adjusting knob is fixed to the outer side of the lower end of the first driving rod; a first sliding groove is formed in the side edge of the first operating platform, a second sliding groove is correspondingly formed in the side edge of the bottom plate, the upper end of the first driven rod is embedded into the first sliding groove, and the lower end of the first driven rod is embedded into the second sliding groove;
the width direction of the bottom plate is used as the X direction, the length direction of the bottom plate is used as the Y direction, the X direction and the Y direction are perpendicular to each other, and the extending direction of the first sliding groove and the extending direction of the second sliding groove are parallel to the Y direction.
2. The adjustable console suitable for a rat brain stereotaxic apparatus according to claim 1, wherein: the second lifting mechanism comprises a second driving rod, a second driven rod and a second adjusting knob, the middle part of the second driving rod is hinged with the middle part of the second driven rod, the second driving rod and the second driven rod are in an X shape, the upper end of the second driving rod is hinged to the side edge of the second operating platform, the lower end of the second driving rod is hinged to the side edge of the bottom plate, and the second adjusting knob is fixed to the outer side of the lower end of the second driving rod; the side of the second operation platform is provided with a third sliding groove, the side of the bottom plate is correspondingly provided with a fourth sliding groove, the upper end of the second driven rod is correspondingly embedded into the third sliding groove, and the lower end of the second driven rod is correspondingly embedded into the fourth sliding groove.
3. The adjustable console suitable for a rat brain stereotaxic apparatus according to claim 1, wherein: including vertical adjustment mechanism, vertical adjustment mechanism includes first base, first base is on a parallel with the bottom plate, follow on the first base the Y direction is equipped with first guide rail, be equipped with first slider on the first guide rail, the top surface fixed connection of first slider the bottom surface of bottom plate, the side of first slider is connected with first regulation pole, first regulation pole is followed the X direction sets up.
4. The adjustable operating console suitable for the rat brain stereotaxic apparatus according to claim 3, wherein: including horizontal adjustment mechanism, horizontal adjustment mechanism includes the second base, the second base is on a parallel with the bottom plate, follow on the second base the X direction is equipped with the second guide rail, be equipped with the second slider on the second guide rail, the top surface fixed connection of second slider the bottom surface of first base, the side of second slider is connected with the second and adjusts the pole, the second is adjusted the pole and is followed the Y direction sets up.
5. The adjustable console suitable for a rat brain stereotaxic apparatus according to claim 4, wherein: and the bottom surface of the second base is provided with an anti-skid groove.
6. The adjustable console suitable for a rat brain stereotaxic apparatus according to claim 1, wherein: the improved four-limb.
7. The adjustable console suitable for a rat brain stereotaxic apparatus according to claim 1, wherein: one side that first operation panel kept away from the second operation panel is equipped with the afterbody mount, the afterbody mount is the loudspeaker form, just the inner opening of afterbody mount is big, the outer end opening is little.
8. The adjustable console suitable for a rat brain stereotaxic apparatus according to claim 7, wherein: the tail fixing frame comprises an upper half part and a lower half part, wherein the upper half part is hinged with one side of the lower half part, and the other side of the upper half part is detachably connected with the other side of the lower half part through a fastening bolt.
9. The adjustable console suitable for a rat brain stereotaxic apparatus according to claim 1, wherein: the upper end of the first driven rod is provided with a first embedded block, and the structure of the first embedded block is matched with that of the first sliding groove; and a second embedded block is arranged at the lower end of the first driven rod, and the structure of the second embedded block is matched with that of the second sliding groove.
10. The adjustable console suitable for a rat brain stereotaxic apparatus according to claim 2, wherein: a third embedded block is arranged at the upper end of the second driven rod, and the structure of the third embedded block is matched with that of the third sliding groove; and a fourth embedded block is arranged at the lower end of the second driven rod, and the structure of the fourth embedded block is matched with that of the fourth sliding groove.
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| CN201911115244.3A CN110680553A (en) | 2019-11-14 | 2019-11-14 | Adjustable operation panel suitable for rat brain stereotaxic apparatus |
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| CN201911115244.3A CN110680553A (en) | 2019-11-14 | 2019-11-14 | Adjustable operation panel suitable for rat brain stereotaxic apparatus |
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| CN114041958A (en) * | 2020-01-19 | 2022-02-15 | 中山大学中山眼科中心 | Rodent ophthalmic surgical platform with heating plate |
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