CN208611038U - A kind of dedicated fixed station of mouse bone marrow cells puncture - Google Patents
A kind of dedicated fixed station of mouse bone marrow cells puncture Download PDFInfo
- Publication number
- CN208611038U CN208611038U CN201820132111.1U CN201820132111U CN208611038U CN 208611038 U CN208611038 U CN 208611038U CN 201820132111 U CN201820132111 U CN 201820132111U CN 208611038 U CN208611038 U CN 208611038U
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- Prior art keywords
- forelimb
- bone marrow
- fixed station
- puncture
- hind leg
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- 210000003141 lower extremity Anatomy 0.000 claims abstract description 36
- 210000003194 forelimb Anatomy 0.000 claims abstract description 34
- 230000000694 effects Effects 0.000 claims abstract description 15
- 238000009434 installation Methods 0.000 claims description 4
- 210000003414 extremity Anatomy 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 210000002303 tibia Anatomy 0.000 abstract description 10
- 238000000034 method Methods 0.000 abstract description 6
- 238000009583 bone marrow aspiration Methods 0.000 abstract description 4
- 238000002474 experimental method Methods 0.000 abstract description 4
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- 208000012260 Accidental injury Diseases 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The utility model relates to a kind of mouse bone marrow cells to puncture dedicated fixed station, including the fixed device of operation bottom plate, forelimb, the fixed device of hind leg；It operates substrate and is equipped with a lateral fixing groove longitudinal rail parallel with two；Lateral fixing groove inner wall is equipped with internal screw thread, and longitudinal rail bottom is equipped with slide teeth, inner wall is equipped with sliding groove；The fixed device of forelimb is made of main body rack, activity lock, arc cushion and forelimb bandage；The fixed device of hind leg is made of telescopic rod, lock nut, hind leg fixed station and hind leg bandage.Its advantage is shown: the fixed method of hand-held shin bone is abandoned, to reduce the probability that operator is accidentally injured by syringe needle；The height of telescopic rod can be adjusted, to adjust the angle of mouse tibia and table top, be applicable to the bone marrow aspiration of different week old mouse；The design of longitudinal rail and the fixed device of forelimb, can be fixed the mouse of different length, ensure that experiment effect.
Description
Technical field
The utility model relates to technical field of medical instrument, specifically, being a kind of dedicated fixed station of mouse bone marrow cells puncture.
Background technique
Bone marrow puncture (Bone Marrow Puncture) is a kind of common diagnostic techniques of clinically bone marrow extraction liquid.
Be the proliferative conditions of long term monitoring mouse bone marrow cells when constructing mouse leukemia model, it would be desirable to acquire the bone marrow fluid of mouse into
Row analysis.However, not only having lacked mature mouse living body bone in zoopery wears technology, but also lack the bone marrow aspiration for being suitable for mouse
Fixed device.
In order to overcome this difficulty, the method that we have used for reference rat marrow puncture is improved: 1, by mouse peritoneal fiber crops
Liquor-saturated, preserved skin at knee joint, mouse takes lateral position, and experimenter's index finger and thumb fix the shin bone of mouse；2, with common 1ml mono-
Secondary property is pierced into tibial shaft from tibial plateau from the knee joint of mouse using asepsis injector, penetrates after fixing and extracts；3, it uses
The sterile insulin syringe of 1ml of anti-coagulants lubrication is pierced into shin bone pulp cavity, bone marrow extraction liquid along 1ml syringe puncture orifice.But
Be that this experimental method still remains many defects: 1, experimenter fixes mouse tibia manually, and finger is easy to be missed by syringe needle
Wound, it is abnormally dangerous；2, it is not easy to neophyty operation.
So being badly in need of a kind of dedicated fixed station of mouse bone marrow cells puncture that can solve the above problem at present.
Chinese patent literature: CN106344203A, publication date: 2017.01.25 discloses a kind of tiltable curved surface constant temperature
Mouse fixing device, including front plate and backplate, four angles of front plate are equipped with fixed column, are provided in front plate small for accommodating
The groove of mouse, groove inner wall are curved surface, and four angles of backplate are equipped with stabilizer blade, and stabilizer blade is elevating feet, and elevating feet includes rising
Drop bar and adjusting nut, adjusting nut are set to elevating lever side；It is also connected with by fixed column between front plate and backplate
Concave temperature-constant plate, concave temperature-constant plate are close to front plate outer wall.
Chinese patent literature: CN106344203A, publication date: 2017.01.25 discloses a kind of big/small mouse for experiment tail blood
Pipe takes blood and injection to keep the temperature fixed station, including station and heating device, and heating device, station are housed below station
Four angles on an adjusting support is respectively installed, station is equipped with a translucent cover, and one end of translucent cover blocks, and
The end is equipped with air hole, and the other end of translucent cover is equipped with rubber stopper, and rubber stopper is equipped with rat-tail fixation hole, is equipped with one in translucent cover
It is a to move and securing baffle.
Chinese patent literature: CN103610515A, publication date: 2014.03.05 discloses a kind of mouse tail vein injection
Fixation device, including two groups of symmetrically arranged baffle plate assemblies, rotatable chassis, fixing clamp and rotatable chassis drive shaft, two groups
Baffle plate assembly is placed on rotatable chassis, and every group of baffle plate assembly includes that lateral coaming plate, rear side baffle, head fixed plate and tail portion are fixed
Plate, rear side baffle one end are fixedly connected with lateral coaming plate, and the other end is fixedly connected with tail portion fixed plate, have neck in the fixed plate of head
Locating slot, the neck of mouse is blocked in the neck locating slot cooperation in the head fixed plate in two groups of baffle plate assemblies, to the head of mouse
Portion is limited；Tail portion fixed plate cooperation in two groups of baffle plate assemblies limits the tail portion of mouse；Tail portion fixed plate lower part
There is mousetail to pass through channel；Fixing clamp includes fixing clamp baffle, rat-tail folder, fixing clamp card slot, and fixing clamp card slot is respectively with two
The rear side baffle grafting of group baffle plate assembly.
But dedicated fixed station is punctured about the mouse bone marrow cells of the utility model and yet there are no report.
Summary of the invention
The purpose of this utility model is to provide a kind of accidental injury that can reduce experimenter and improves conventional efficient and successfully
The mouse bone marrow cells of rate puncture dedicated fixed station.
To achieve the above object, the technical scheme adopted by the utility model is that:
A kind of dedicated fixed station of mouse bone marrow cells puncture, it includes operation bottom plate that the mouse bone marrow cells, which puncture dedicated fixed station,
(1), forelimb fixed device (2), hind leg are fixed device (3)；The operation bottom plate (1) in a rectangular parallelepiped shape, at the operation bottom
Plate (1) is equipped with lateral fixing groove (11) longitudinal rail (12) parallel with two above；The transverse direction fixing groove (11)
Inner wall is equipped with internal screw thread (111), and the bottom of the longitudinal rail (12) is equipped with slide teeth (121), inner wall is equipped with sliding groove
(122)；Forelimb is installed fixed device (2) in the longitudinal rail (12)；The forelimb fixed device (2) is by main body branch
Frame (21), activity lock (22), arc cushion (23) and forelimb bandage (24) composition；The left side and the right side of the main body rack (21)
Face is equipped with sliding groove protrusion (211), and the bottom of the main body rack (21) is equipped with activity lock (22), in the active lock
The front and back for detaining (22) is equipped with lock button (221), is equipped with lock tooth in the bottom of the activity lock (22)
(222)；There are two arc cushion (23) for the connection of the upper surface of described main body rack (21), connect on the arc cushion (23)
There are two forelimb bandages (24)；There are two hind legs to fix device (3) for installation in the lateral fixing groove (11)；The hind leg
Fixed device (3) are made of telescopic rod (31), lock nut (32), hind leg fixed station (33) and hind leg bandage (34)；Described
The side of telescopic rod (31) bottom is equipped with external screw thread (311), is connected with lock nut (32) on the external screw thread (311)；?
The upper end of the telescopic rod (31) is fixedly connected with hind leg fixed station (33), is connected with two on the hind leg fixed station (33)
Hind leg bandage (34).
The forelimb fixed device (2) can the sliding in longitudinal rail (12).
The lock button (221) is used to lock the position of forelimb fixed device (2).
The sliding groove raised (211) and the sliding groove (122) match, the internal screw thread (111) and institute
The external screw thread (311) stated matches.
The length of the telescopic rod (31) can be changed.
The utility model advantage is:
1, the mouse bone marrow cells of the utility model puncture dedicated fixed station and abandon the fixed method of hand-held shin bone, to reduce
The probability that operator is accidentally injured by syringe needle；The bone wears fixed station and is equipped with the telescopic rod for raising mouse tibia, and the height of telescopic rod can
To be adjusted, to adjust the angle of mouse tibia and table top, it is applicable to the bone marrow aspiration of different week old mouse.
2, the mouse bone marrow cells of the utility model puncture the design of the fixed device of dedicated fixed station longitudinal rail and forelimb, can be with
The mouse of different length is fixed, ensure that experiment effect.
3, the dedicated fixed station of mouse bone marrow cells puncture of the utility model is low in cost, convenient for production and repacking.
Detailed description of the invention
Attached drawing 1 is the structural schematic diagram that a kind of mouse bone marrow cells puncture dedicated fixed station.
Attached drawing 2 is the operation structural diagram of base plate that a kind of mouse bone marrow cells puncture dedicated fixed station.
Attached drawing 3 is the forelimb fixture structure schematic diagram that a kind of mouse bone marrow cells puncture dedicated fixed station.
Attached drawing 4 is the forelimb fixture structure schematic diagram that a kind of mouse bone marrow cells puncture dedicated fixed station.
Attached drawing 5 is the hind leg fixture structure schematic diagram that a kind of mouse bone marrow cells puncture dedicated fixed station.
Attached drawing 6 is the hind leg fixture structure schematic diagram that a kind of mouse bone marrow cells puncture dedicated fixed station.
Attached drawing 7 is the structural schematic diagram that a kind of mouse bone marrow cells puncture dedicated fixed station.
Attached drawing 8 is that a kind of mouse bone marrow cells puncture the top view that dedicated fixed station uses.
Specific embodiment
The utility model is further described below with reference to embodiment and referring to attached drawing.
Appended drawing reference involved in attached drawing and component part are as follows:
1, bottom plate is operated
11, lateral fixing groove
111, internal screw thread
12, longitudinal rail
121, slide teeth
122, sliding groove
2, the fixed device of forelimb
21, main body rack
211, sliding groove protrusion
22, activity lock
221, button is latched
222, tooth is latched
23, arc cushion
24, forelimb bandage
3, the fixed device of hind leg
31, telescopic rod
311, external screw thread
32, lock nut
33, hind leg fixed station
34, hind leg bandage
4, mouse
Embodiment 1
Attached drawing 1 is please referred to, attached drawing 1 is that a kind of mouse bone marrow cells of the present embodiment puncture the structural schematic diagram of dedicated fixed station.
It is fixed device (3) including operation bottom plate (1), forelimb fixed device (2), hind leg that the mouse bone marrow cells puncture dedicated fixed station.
Attached drawing 2 is please referred to, attached drawing 2 is that a kind of mouse bone marrow cells of the present embodiment puncture the operation floor structure of dedicated fixed station
Schematic diagram.The operation bottom plate (1) is equipped with a lateral fixing groove in a rectangular parallelepiped shape, in the operation bottom plate (1) above
(11) longitudinal rail parallel with two (12)；The inner wall of the transverse direction fixing groove (11) is equipped with internal screw thread (111), described vertical
The bottom of direction guiding rail (12) is equipped with slide teeth (121), inner wall is equipped with sliding groove (122)；Installation in the longitudinal rail (12)
There is forelimb fixed device (2).
Attached drawing 3, attached drawing 4 are please referred to, attached drawing 3,4 is that a kind of mouse bone marrow cells of the present embodiment puncture the forelimb of dedicated fixed station
Fixture structure schematic diagram.The forelimb fixed device (2) is by main body rack (21), activity lock (22), arc cushion
(23) it is formed with forelimb bandage (24)；The left side and the right side of the main body rack (21) are equipped with sliding groove protrusion (211), described
The bottom of main body rack (21) is equipped with activity lock (22), is equipped with lock in the front and back of the activity lock (22) and presses
Button (221) is equipped with lock tooth (222) in the bottom of the activity lock (22)；The connection of the upper surface of described main body rack (21)
There are two arc cushion (23), and two forelimb bandages (24) are connected on the arc cushion (23)；The transverse direction is solid
Determining installation in slot (11), there are two hind legs to fix device (3).
Attached drawing 5, attached drawing 6 are please referred to, attached drawing 5,6 is that a kind of mouse bone marrow cells of the present embodiment puncture the hind leg of dedicated fixed station
Fixture structure schematic diagram.The hind leg fixed device (3) is by telescopic rod (31), lock nut (32), hind leg fixed station
(33) it is formed with hind leg bandage (34)；External screw thread (311) are equipped in the side of the telescopic rod (31) bottom, the external screw thread
(311) lock nut (32) are connected on；It is fixedly connected with hind leg fixed station (33) in the upper end of the telescopic rod (31), it is described
Hind leg fixed station (33) on be connected with two hind leg bandages (34).
Attached drawing 7 is please referred to, attached drawing 7 is that a kind of mouse bone marrow cells of the present embodiment puncture the structural schematic diagram of dedicated fixed station.
The forelimb fixed device (2) can the sliding in longitudinal rail (12)；The lock button (221) is for locking forelimb
The position of fixed device (2)；The sliding groove raised (211) and the sliding groove (122) match, the internal screw thread
(111) it matches with the external screw thread (311)；The length of the telescopic rod (31) can be changed.
Embodiment 2
Attached drawing 1, attached drawing 7, attached drawing 8 are please referred to, attached drawing 1,7 is that a kind of mouse bone marrow cells of the present embodiment puncture dedicated fixed station
Structural schematic diagram, attached drawing 8 is that a kind of mouse bone marrow cells of the present embodiment puncture the top view that dedicated fixed station uses.
The mouse bone marrow cells puncture the use process and method of dedicated fixed station:
It will be lain on the back after mouse (4) intraperitoneal injection of anesthesia first in operation bottom plate (1), double upper limbs pass through the fixed device of forelimb
(2) the forelimb bandage (24) on is fixed after knotting；Forelimb fixed device (2) can slide in longitudinal rail (12), can be right
The mouse (4) of different length is fixed.The posture that double lower limb (or side lower limb) takes hip joint outward turning, knee bends, by shin
Bone middle and upper part rests on the hind leg fixed station (33) on hind leg fixed device (3), and after being fixed in hind leg bandage (34)
On limb fixed device (3).The height of telescopic rod (31) can be changed, make shin bone and operation bottom plate (1) horizontal plane in 30 ° extremely
45 ° of easy-operating angles.The design of lateral fixing groove (11) simultaneously can make hind leg fixed device (3) be fixed on lateral fixation
The different location of slot (11) can be adapted for different size of mouse (4).Then alcohol wipe knee joint surface, preserved skin, then into
Row bone marrow aspiration.
The above is only the preferred embodiment of the utility model, it is noted that for the common skill of the art
Art personnel can also make several improvement and supplement without departing from the principle of this utility model, these are improved and supplement
Also it should be regarded as the protection scope of the utility model.
Claims (5)
1. a kind of mouse bone marrow cells puncture dedicated fixed station, which is characterized in that the mouse bone marrow cells puncture dedicated fixed station and include
Operate bottom plate (1), forelimb fixes device (2), hind leg fixes device (3)；The operation bottom plate (1) in a rectangular parallelepiped shape, in institute
It states operation bottom plate (1) and is equipped with lateral fixing groove (11) longitudinal rail (12) parallel with two above；It is described laterally fixed
The inner wall of slot (11) is equipped with internal screw thread (111), and the bottom of the longitudinal rail (12) is equipped with slide teeth (121), inner wall is equipped with
Sliding groove (122)；Forelimb is installed fixed device (2) in the longitudinal rail (12)；The forelimb fixed device (2) by
Main body rack (21), activity lock (22), arc cushion (23) and forelimb bandage (24) composition；A left side for the main body rack (21)
Face and the right side are equipped with sliding groove protrusion (211), and the bottom of the main body rack (21) is equipped with activity lock (22), described
The front and back of activity lock (22) is equipped with lock button (221), is equipped with lock in the bottom of the activity lock (22)
Tooth (222)；There are two arc cushion (23) for the connection of the upper surface of described main body rack (21), connect on the arc cushion (23)
It is connected to two forelimb bandages (24)；There are two hind legs to fix device (3) for installation in the lateral fixing groove (11)；After described
Limb fixed device (3) is made of telescopic rod (31), lock nut (32), hind leg fixed station (33) and hind leg bandage (34)；Institute
The side for stating telescopic rod (31) bottom is equipped with external screw thread (311), is connected with lock nut (32) on the external screw thread (311)；
It is fixedly connected with hind leg fixed station (33) in the upper end of the telescopic rod (31), is connected with two on the hind leg fixed station (33)
Bar hind leg bandage (34).
2. mouse bone marrow cells according to claim 1 puncture dedicated fixed station, which is characterized in that the fixed device of the forelimb
It (2) can the sliding in longitudinal rail (12).
3. mouse bone marrow cells according to claim 1 puncture dedicated fixed station, which is characterized in that the lock button
(221) for locking the position of forelimb fixed device (2).
4. mouse bone marrow cells according to claim 1 puncture dedicated fixed station, which is characterized in that the sliding groove protrusion
(211) it matches with the sliding groove (122), the internal screw thread (111) and the external screw thread (311) match.
5. mouse bone marrow cells according to claim 1 puncture dedicated fixed station, which is characterized in that the length of the telescopic rod (31)
Degree can be changed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820132111.1U CN208611038U (en) | 2018-01-26 | 2018-01-26 | A kind of dedicated fixed station of mouse bone marrow cells puncture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820132111.1U CN208611038U (en) | 2018-01-26 | 2018-01-26 | A kind of dedicated fixed station of mouse bone marrow cells puncture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208611038U true CN208611038U (en) | 2019-03-19 |
Family
ID=65691153
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| CN201820132111.1U Expired - Fee Related CN208611038U (en) | 2018-01-26 | 2018-01-26 | A kind of dedicated fixed station of mouse bone marrow cells puncture |
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| Country | Link |
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| CN (1) | CN208611038U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110680553A (en) * | 2019-11-14 | 2020-01-14 | 南京市中医院 | Adjustable operation panel suitable for rat brain stereotaxic apparatus |
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2018
- 2018-01-26 CN CN201820132111.1U patent/CN208611038U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110680553A (en) * | 2019-11-14 | 2020-01-14 | 南京市中医院 | Adjustable operation panel suitable for rat brain stereotaxic apparatus |
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Granted publication date: 20190319 |