CN110651791A - Application of calcium quinolate in preventing and treating plant diseases and composition thereof - Google Patents
Application of calcium quinolate in preventing and treating plant diseases and composition thereof Download PDFInfo
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- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
- A01N43/42—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
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- A—HUMAN NECESSITIES
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- A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
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Abstract
The invention relates to application of calcium quinolate in preventing and treating plant diseases, and a composition thereof, wherein the calcium quinolate is used for preventing and treating one or more of plant fungal diseases, plant bacterial diseases or plant nutritional deficiency diseases caused by calcium deficiency. The invention discovers that the quinoline calcium can not cause heavy metal pollution of soil and heavy metal residue of crops, and that plants can enhance the absorption of the crops to the calcium and enhance the resistance of the plants to some pathogenic bacteria through the action of the quinoline calcium, thereby avoiding or reducing the damage and the occurrence of the pathogenic bacteria and having longer lasting period for preventing and controlling the crop diseases.
Description
Technical Field
The invention belongs to the field of bactericides and plant growth regulators, relates to application of calcium quinolate in preventing and treating plant diseases or application of calcium quinolate in preventing and treating plant diseases caused by calcium deficiency, and also relates to a pesticide composition containing calcium quinolate, application of the pesticide composition and a pesticide application method of the pesticide composition.
Background
The bactericide is a compound having a poisoning effect on pathogenic microorganisms. The principle of the bactericide for preventing and treating plant diseases is divided into three principles, namely chemical protection, chemical treatment and chemical immunity. On one hand, the bactericide directly generates toxicity to pathogenic bacteria, and on the other hand, the bactericide changes the metabolism of plants and changes the reaction of the plants to the pathogenic bacteria or the pathogenic process of the pathogenic bacteria. However, most systemic bactericides have only one function, and some bactericides have two functions.
Methods for preparing calcium quinolinate have been disclosed in the prior art, for example, J fluoro (2012) 22: 1271-1279, I.M. Nangpure et al disclose "Synthesis, Thermal and Spectroscopic Characterisationof Caq2(Calcium 8-Hydroxyquinoline) Organic Phosphor". Also disclosed are methods for preparing calcium 8-quinolinolate, such as that disclosed in CN105348191B, and methods for preparing a luminescent material, such as calcium 8-quinolinolate, such as that disclosed in CN 105439950A.
Although the prior art discloses a method for preparing 8-hydroxyquinoline calcium, the application of quinoline calcium is limited to organic electroluminescent materials, and agricultural application is not involved.
In the copper preparation applied to the current pesticide, particularly the oxine-copper, in 2017, 10 and 27 days, the carcinogen list published by the international cancer research institution of the world health organization is preliminarily collated and referred, and the 8-hydroxyquinolinone-copper is in the class-3 carcinogen list. The application of the oxine-copper is greatly limited, but the oxine-copper is in short supply on the market at present as a substitute product of the oxine-copper.
The invention not only finds that the calcium quinolate can prevent and treat plant diseases, but also finds that the calcium quinolate is superior to the prior similar plant disease control medicament in the effect of preventing and treating the plant diseases.
Disclosure of Invention
To solve the above technical problems, the present invention provides a use of a compound having the following chemical formula a for plant disease control, the chemical formula of the compound having the chemical formula a being as follows:
wherein the plant disease is one or more of plant fungal disease, plant bacterial disease or plant auxotrophy caused by calcium deficiency.
Preferably, the plant disease is a fungal disease of a plant and a calcium deficiency resulting in a plant auxotrophy.
Preferably, the plant disease is a bacterial disease and a calcium deficiency in the plant resulting in a plant auxotrophy.
The compounds of the above formula A are also referred to below simply as quinolinium calcium or simply as 8-hydroxyquinolinium salt.
Preferably, in the above use, the plant is preferably a crop plant selected from any one of cereals, fruit trees, vegetables, sugar plants, oil crops, tobacco plants and tea trees.
Specifically, cereals such as wheat, barley, rice, sorghum; fruit trees such as apple, pear, peach, orange, grape, lychee, banana, longan, mango, loquat; vegetables such as cucumber, watermelon, snake gourd, luffa, melon, spinach, celery, tomato, capsicum, eggplant, ginger, shallot, garlic, leek, cabbage, Chinese cabbage, strawberry, asparagus lettuce, kidney bean, cowpea, broad bean, radish, carrot, potato, yam, taro, lotus root, water chestnut, water bamboo, sweet potato; sugar plants such as sugar beet, sugar cane; oil crops such as soybean, peanut, rape, sesame and sunflower. This list is not meant to be limiting in any way.
Preferably, in the above use, the control of plant diseases is carried out by applying calcium quinolinate to plants and plant parts.
Plant parts are, among others, all above-ground and underground parts and plant organs, such as shoots, leaves, flowers and roots, for example leaves, needles, stems, flowers, fruit bodies, fruits and seeds, and roots, tubers and rhizomes. Plant parts also include harvested material and vegetative and generative propagation material, such as seedlings, tubers, rhizomes, cuttings and seeds. Preference is given to treating plants and parts above and below the ground and plant organs, such as shoots, leaves, flowers and roots, such as leaves, needles, stems, flowers and fruits.
Preferably, the compound is used for preventing and treating plant diseases, wherein the plant diseases are rice bacterial blight, rice basal rot, cucumber angular leaf spot, tomato early blight, rice bacterial leaf streak, tomato late blight, apple alternaria leaf spot, grape downy mildew or peach bacterial leaf spot.
Preferably, in the application of the compound for controlling plant diseases, the effective dosage of the compound for controlling plant diseases is 15-1500 g/ha, and preferably, the effective dosage of the compound for controlling plant diseases is 100-500 g/ha.
In another aspect, the present invention also provides a pharmaceutical composition for controlling plant diseases, comprising the compound of formula A and agriculturally, forestry or hygienically acceptable adjuvants and carriers,
wherein the weight of the compound with the chemical formula A accounts for 1-99% of the weight of the pharmaceutical composition, and the sum of the weight of the auxiliary agent and the carrier accounts for 1-99% of the weight of the pharmaceutical composition.
Preferably, in the above pharmaceutical composition for controlling plant diseases, the formulation of the pharmaceutical composition is a suspension, a suspoemulsion, an aqueous dispersion granule or a wettable powder.
Preferably, the adjuvant or carrier in the pharmaceutical composition includes wetting agent, dispersing agent, thickening agent, anti-freezing agent, preservative, stabilizer, film forming agent, encapsulating agent, pH adjusting agent, antifoaming agent, coloring agent, filler, water and the like, and other known substances beneficial to the stabilization of the effective ingredient in the formulation or the exertion of the active compound, which are various ingredients commonly used in the preparation or agriculturally allowed, and are not particularly limited, and the specific ingredients and amounts thereof are determined by experiments as needed.
The wetting agent is selected from one or more of EO/PO block polyether, fatty alcohol-polyoxyethylene ether, tallow ethoxy ammonium salt, alkyl naphthalene sulfonate, fatty alcohol-polyoxyethylene ether sulfate and acyl glutamate;
the dispersing agent is selected from one or more of naphthalene sulfonic acid condensate sodium salt, phenol sulfonic acid condensate sodium salt, methyl naphthalene sulfonic acid sodium formaldehyde condensate, sodium lignosulfonate, methylene dinaphthyl sodium sulfonate, acrylic acid homopolymer sodium salt, high molecular polycarboxylate, dioctyl sulfosuccinic acid sodium salt, EO/PO block polyether and maleic acid-acrylic acid copolymer sodium salt;
the thickening agent is selected from one or more of xanthan gum, magnesium aluminum silicate, sodium carboxymethylcellulose, sodium starch phosphate, sodium starch octenyl succinate and polyvinyl alcohol;
the antifreezing agent is selected from one or more of ethylene glycol, propylene glycol, glycerol, isopropanol and urea;
the film forming agent is selected from one or more of high molecular polymers with adhesive property and film forming property, such as polyvinyl alcohol, polyvinyl acetate, polyethylene glycol methacrylate, carboxymethyl cellulose, gum arabic, xanthan gum, starch and the like;
the encapsulating agent is polyurea resin; is prepared by the interfacial polymerization reaction of isocyanate monomer and polyol or polyamine; the isocyanate includes tolylene diisocyanate, 4-diphenylmethane diisocyanate, polyphenyl polymethylene polyisocyanate and the like.
The pH acid-base regulator is selected from one or more of citric acid, glacial acetic acid, hydrochloric acid, ammonia water, triethanolamine and diethylenetriamine; the required dosage is that the PH value of the final product is adjusted to be in a stable range;
the defoaming agent is selected from an organic silicon defoaming agent and/or a polyether defoaming agent;
the colorant is selected from one or more of ferric oxide, titanium oxide and azo dye;
the filler is selected from one or more of kaolin, diatomite, talcum powder, light calcium carbonate and white carbon black;
the water is deionized water or distilled water.
Preferably, in the above pharmaceutical composition for controlling plant diseases, the content of the compound of formula a in the pharmaceutical composition is 20 to 60% by weight.
The invention also provides application of the pharmaceutical composition in preventing and treating plant diseases, wherein the plant diseases are one or more of plant fungal diseases, plant bacterial diseases or plant nutritional deficiency diseases caused by calcium deficiency.
Preferably, the pharmaceutical composition is used for preventing and treating plant diseases, the weight content of the compound in the pharmaceutical composition is 20-60%, and the dilution factor is 100-4000 times when the pharmaceutical composition is applied.
Preferably, the pharmaceutical composition is used for controlling plant diseases, such as rice bacterial blight, rice basal rot, cucumber angular leaf spot, tomato early blight, rice bacterial leaf streak, tomato late blight, apple alternaria leaf spot, grape downy mildew or peach bacterial leaf spot.
The invention also provides a method for controlling plant diseases by using the pharmaceutical composition, which is characterized in that the pharmaceutical composition is applied to plants needing to be controlled for diseases or a medium needing to be controlled for harmful bacteria or fungi at an effective dose of 15 g to 1500g of quinoline calcium per hectare. Preferably, the pharmaceutical composition is applied to the plants in need of control of disease or to a medium in need of control of harmful bacteria or fungi at an effective dose of 100 to 300 grams of calcium quinolinate per hectare.
In the process of preventing and treating plant diseases, the pharmaceutical composition can adopt methods such as spraying, seed dressing, irrigating, broadcasting or brushing and the like according to different properties of target diseases, and the dosage of the applied effective active ingredients can be adjusted and changed according to weather conditions, plant states or application methods.
The invention has the advantages of
The invention discovers that calcium quinolate has better effect of preventing and treating diseases than similar medicaments such as copper quinolate, zinc quinolate and zinc thiazole, and the effect of preventing and treating diseases by the copper quinolate can be achieved by using smaller amount.
The invention discovers that the quinoline calcium has good safety and effects of preventing and treating diseases on some crops (peaches and apples) sensitive to copper preparations.
The invention discovers that the quinoline calcium can not cause heavy metal pollution of soil and heavy metal residue of crops, and that plants can enhance the absorption of the crops to the calcium and enhance the resistance of the plants to some pathogenic bacteria through the action of the quinoline calcium, thereby avoiding or reducing the damage and the occurrence of the pathogenic bacteria and having longer lasting period for preventing and controlling the crop diseases.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in the following specific embodiments, which are for better explaining the present invention and not for limiting the scope of the present invention, and all modifications and variations made based on the basic ideas and principles of the present invention are included in the scope of the present invention as claimed. Therefore, the protection scope of the present invention should be subject to the claims.
Indoor bioassay example:
the raw quinoline calcium and the preparation adopted in the test are provided by Jiaxing Shicheng trade company Limited; the strains for the bioassay test are provided by the plant protection academy of agriculture and forestry university in Zhejiang, the agriculture academy of Yangtze university and the agriculture academy of Jilin agriculture science and technology academy of agriculture, and are usually stored on a (PDA) inclined plane at 4 ℃.
Indoor bioassay example 1: bacterial resistance experiment of rice bacterial leaf blight
The test method comprises the following steps: the oxford standard method (coating method), the following data are each a total of 9 cups of bacteriostatic area. The tested medicaments are 96% of quinoline calcium raw powder, 96% of quinoline zinc raw powder, 95% of thiazole zinc raw powder and 99% of quinoline copper standard samples, and the tested concentrations of all the medicaments are 20, 4 and 2 mg/L.
The test result shows that: the antibacterial activity on rice bacterial blight, calcium quinolate and copper quinolate is very high, the activity of the calcium quinolate is obviously higher than that of the copper quinolate under high concentration, and the time difference is not obvious under low concentration; quinoline zinc and the current conventional control agent thiazole zinc do not show activity on a plate test. See tables 1 and 2 below for specific results.
Table 1: antibacterial effect of the antibacterial agent on rice bacterial leaf blight bacteria in 24 hours and 48 hours
Table 2: antibacterial effect of the antibacterial agent on rice bacterial leaf blight bacteria in 72 hours and 96 hours
Indoor bioassay example 2: antibacterial experiment of rice basal rot
The test method comprises the following steps: the oxford standard method (coating method), the following data are each a total of 9 cups of bacteriostatic area. The tested medicaments are 96% of quinoline calcium raw powder, 96% of quinoline zinc raw powder, 95% of thiazole zinc raw powder and 99% of quinoline copper standard samples, and the tested concentrations of all the medicaments are 20, 4 and 2 mg/L.
The test result shows that: the compound has high bacteriostatic activity on rice basal saprophytic bacteria, namely calcium quinolate and copper quinolate, the activity of the calcium quinolate is obviously higher than that of the copper quinolate at high concentration, and the time difference is not obvious at low concentration; quinoline zinc and the current conventional control agent thiazole zinc do not show activity on a plate test. See tables 3 and 4 below for specific results.
Table 3: antibacterial effect of the antibacterial agent on rice basal rot fungi in 24 hours and 48 hours
Table 4: antibacterial effect of the antibacterial agent on rice basal rot fungi in 72 hours and 96 hours
Indoor bioassay example 3: cucumber angular leaf spot germ antibacterial experiment
The test method comprises the following steps: the oxford standard method (coating method), the following data are each a total of 9 cups of bacteriostatic area. The tested medicaments are 96% of quinoline calcium raw powder, 96% of quinoline zinc raw powder, 95% of thiazole zinc raw powder and 99% of quinoline copper standard samples, and the tested concentrations of all the medicaments are 20, 4 and 2 mg/L.
The test result shows that: the antibacterial agent has certain antibacterial activity on cucumber angular leaf spot germs, calcium quinolate, zinc quinolate and copper quinolate, wherein the calcium quinolate is slightly better than the calcium quinolate, and the calcium quinolate is slightly better than the zinc quinolate; zinc thiazole showed no activity in the plate assay. See table 5 below for specific results.
Table 5: antibacterial effect of the antibacterial agent on rice basal rot fungi at 24, 48 and 72 hours
Indoor bioassay example 4: tomato early blight bacterium antibacterial experiment
The test method comprises the following steps: oxford standard method (coating method), the data below are each an average of 6 cup colony radii. The test agents were 96% quinoline calcium raw powder, 96% quinoline zinc raw powder, and 99% quinoline copper standard sample.
The test result shows that: the antibacterial agent has good antibacterial activity on tomato early blight bacteria, quinoline calcium, quinoline zinc and quinoline copper, the quinoline calcium is slightly better than the quinoline zinc and the quinoline copper, but the activity difference of the quinoline calcium, the quinoline zinc and the quinoline copper is small, and specific results are shown in the following table 6.
Table 6: antibacterial effect of antibacterial agent on tomato early blight bacteria
And (3) field efficacy test:
field test example 1: prevention and treatment of bacterial leaf streak of rice
The causative agent of bacterial leaf streak in rice is Xanthomonas oryzae pv. oryzicola.
The test method comprises the following steps: the field pesticide effect test is carried out according to the pesticide field pesticide effect test criterion (I) (pesticide effect test criterion for preventing and controlling the rice leaf diseases) of Ministry of agriculture, and the test is carried out in Wenzhou, Zhejiang in 8 months in 2017. The tested agents were 33% oxine-copper SC (produced by zhejiang sea chemical industries, ltd.), 20% thiazole zinc SC (produced by zhejiang new chemical industries, ltd.), 2% kasugamycin AS (plant protection services ltd., jiang city); 20% calcium quinolate SC (supplied by Jiaxing Shicheng trade Co., Ltd.) sprayed with 675 kg of water per hectare.
The field test shows that: for bacterial leaf streak of rice, the drug effect of 20% quinoline calcium SC600 times liquid and 20% thiazole zinc SC600 times liquid is superior to that of 2% kasugamycin AS 400 times liquid, and the prevention and treatment effect of the solution is remarkably superior to that of 33% quinoline copper SC1000 times liquid. See table 7 below for specific results.
Table 7: control effect of antibacterial agent on bacterial leaf streak of rice
Field test example 2: prevention and treatment of apple alternaria leaf spot
The causative agent of Alternaria leaf spot in apple is (Alternaria f.
The test method comprises the following steps: the pesticide effect test is carried out according to the pesticide effect test rule I of Ministry of agriculture (No. 124 of the pesticide effect test rule for preventing and controlling apple alternaria leaf spot disease) and the test is carried out in Xiao county of Anhui from 4 months to 7 months in 2017. The test agents are 430g/L tebuconazole SC (produced by Bayer crop science, Inc.) and 60% calcium quinolate WP (provided by Jiaxing Shicheng trading, Inc.), the agent is applied before the alternaria leaf spot is caused, the agent is applied once every 15 days for 6 times, and the water spraying amount per hectare is 675 kilograms.
The field test shows that: for the alternaria leaf spot of apple, the pesticide effect of 60% quinoline calcium WP4000 times liquid is slightly better than the prevention and treatment effect of 430g/L tebuconazole SC4000 times. See table 8 below for specific results.
Table 8: control effect of antibacterial agent on alternaria leaf spot of apple
In the disease control process of apple trees, oxine-copper has phytotoxicity influence on tender leaves of apple trees in flowering period, while quinolinic-calcium has no phytotoxicity influence.
Field test example 3: control of grape downy mildew
The pathogen of grape downy mildew is (Plasmopara viticola (Berk. dt Curtis) Berl. Et de Toni).
The test method comprises the following steps: the pesticide is subjected to a field pesticide effect test according to the first pesticide effect test criterion (pesticide effect test criterion for preventing and treating grape downy mildew diseases) of Ministry of agriculture, and the test is carried out in Jinhua city of Zhejiang in 2017 from 9 months to 10 months. The test agents were 100 g/l cyazofamid SC (manufactured by Nippon Shiyao Kaisha) and 30% quinoline calcium SC (provided by Jiaxing Shicheng trade Co., Ltd.), and the agents were administered at the initial stage of onset of grape downy mildew, once every 15 days and twice in a common manner, and the amount of water sprayed per hectare was 675 kg.
The field test shows that: when the bactericidal composition is used at the initial stage of grape downy mildew, 1200 times of 30% quinoline calcium SC has a better control effect on diseases, and the drug effect is equivalent to 2000 times of 100 g/L cyazofamid SC. See table 9 below for results.
Table 9: control effect of antibacterial agent on grape downy mildew
Field test example 4: prevention and treatment of peach bacterial perforation disease
The causative agent of bacterial peach tree perforation disease is (Xanthomonus pruni (Smith) Dowson.).
The test method comprises the following steps: the diseased leaves are classified into 5 grades: grading diseased leaves: grade 0, no lesion on the whole leaf; 1, 1-5 scabs are formed on each leaf; 2, 6-10 scabs are formed on each leaf; grade 3, 11-15 scabs are formed on each leaf; grade 4, 16-20 spots are formed on each leaf; grade 5, more than 20 spots are formed on each leaf; the test was carried out in Jiaxing city, Zhejiang, 5 months in 2018. The tested agents were 33% oxine-copper SC (produced by zhejiang sea chemical industries, ltd.), 20% thiazole-zinc SC (produced by zhejiang new chemical industries, ltd.), and 30% quinoline-calcium SC (provided by jiaxing shi trade ltd), and were administered once at the initial stage of the development of peach bacterial leaf spot.
The field test shows that: when the pesticide is used at the initial stage of the onset of the peach bacterial perforation disease, three pesticides of 30% of quinoline calcium SC1000 times, 33% of quinoline copper SC1000 times and 20% of thiazole zinc SC1000 times have better control effect on the disease, and the difference between the pesticides is not obvious; the 30% quinoline calcium SC is 100 times of that of the peach tree, has no phytotoxicity and has better prevention and treatment effect than other treatments. See table 10 below for results.
Table 10: prevention and treatment effect of antibacterial agent on peach bacterial perforation disease
Meanwhile, the safety of the quinoline calcium and the quinoline copper to the peach trees is observed, and the fact that the quinoline copper has slight phytotoxicity side effects on the tender leaves of the peach trees is found, particularly, the tender leaves of the peach trees in the flowering period have phytotoxicity influence, and the quinoline calcium does not have any phytotoxicity influence.
Field test example 5: tomato late blight control
The test method comprises the following steps: the field pesticide effect test is carried out according to the pesticide field pesticide effect test criterion (I) (pesticide effect test criterion for preventing and controlling the leaf diseases of the rice by the bactericide) in the Ministry of agriculture, and the test is carried out in Jiaxing city of Zhejiang province in 2017 and 5 months. The test agents were 33% oxine-copper SC (produced by zhejiang sea chemicals ltd), 75% mancozeb WP (produced by the dow-virgine company, usa), and 40% quinolinium SC (provided by the jiaxing sinceri trade ltd), and the amount of water sprayed per hectare was 675 kg per one time.
The field test shows that: for tomato late blight, the 40% quinoline calcium SC1200 and 2000 times of liquid is obviously better than the 33% quinoline copper SC1500 times and 1000 times of liquid, but the medicaments are all better than 75% mancozeb WP800 times of liquid. See table 11 below for specific results.
Table 11: control effect of antibacterial agent on tomato late blight
As the test garden is a vegetable greenhouse for planting solanaceous vegetables for a long time, and the tomato navel rot occurs to a certain extent during the test period in the greenhouse, the investigation is carried out simultaneously, and the navel rot is a physiological disease caused by water supply imbalance, calcium deficiency and boron deficiency. From the following investigation results, the occurrence of the navel rot can be well prevented after the foliar spray of 40% calcium quinoline SC is applied at the early stage of young fruits of tomatoes, which shows that calcium ions can be absorbed by leaves or young fruits, so that the occurrence of the navel rot can be effectively prevented. See table 12 below for specific results.
Table 12: control effect of antibacterial agent on tomato navel rot
Formulation examples:
formulation example 1:
adding 96% of quinoline calcium raw powder 10.4%, acrylic acid homopolymer sodium salt 2%, alkylphenol polyoxyethylene carboxylate 6%, fatty alcohol polyoxyethylene ether 4%, alginic acid 2%, xanthan gum 1%, organic silicone 1% and water to 100%, adding into a sand mill, sanding for 60min, performing secondary serial sanding, and filtering to obtain quinoline calcium 10% SC.
Formulation example 2:
20.8% of quinoline calcium raw powder, 2% of acrylic acid homopolymer sodium salt, 6% of alkylphenol polyoxyethylene carboxylate, 4% of fatty alcohol polyoxyethylene ether, 2% of alginic acid, 1% of xanthan gum, 1% of organic silicone and 100% of water are supplemented, the mixture is put into a sand mill for sanding for 60min, and after secondary serial sanding, filtration is carried out to obtain 20% SC of quinoline calcium.
Formulation example 3:
41.7 percent of 96 percent of quinoline calcium raw powder, 2 percent of ethylene glycol, 0.1 percent of dimethyl polysilane, 0.3 percent of xanthan gum, 3 percent of naphthalenesulfonic acid condensate sodium salt, polyoxyethylene nonyl phenol phosphate and 1 percent of sodium salt of water are supplemented to 100 percent, the mixture is put into a sand mill for sand grinding for 60min, and after secondary serial sand grinding, filtration is carried out to obtain the quinoline calcium 40 percent SC.
Formulation example 4:
96% of quinoline calcium raw powder 62.5%, ethylene glycol 3%, dimethyl polysilane 0.1%, xanthan gum 0.2%, naphthalenesulfonic acid condensate sodium salt 4%, polyoxyethylene nonyl phenol phosphate and sodium salt 1% of water are supplemented to 100%, the mixture is put into a sand mill for sand grinding for 60min, and filtration is carried out after secondary serial sand grinding to obtain 60% of quinoline calcium SC.
Formulation example 5:
96% of quinoline calcium raw powder 62.5%, maleic acid-acrylic acid copolymer sodium salt 6%, tallow ethoxy amine salt 2%, sodium dibutylnaphthalene sulfonate 5%, sodium carboxymethyl starch 10%, attapulgite 10% and white carbon black are supplemented to 100%, put into a stirrer, stirred uniformly and then subjected to airflow crushing to obtain quinoline calcium mother powder; dissolving 2% of Arabic gum and 2% of polyvinyl alcohol in water to prepare a flowable aqueous solution; spraying the water solution into the mother powder while stirring the mother powder, and mixing to obtain a wet material, wherein the water content is 10-30% of the dry matter weight; and extruding, granulating, drying and finishing the wet material to obtain the quinoline calcium 60% WDG.
Formulation example 6:
50.1 percent of quinoline calcium raw powder with the concentration of 96 percent, 3 percent of maleic acid-acrylic acid copolymer sodium salt, 3 percent of condensed naphthalene sulfonate, 2 percent of alkyl naphthalene sulfonate, 3 percent of attapulgite, 4 percent of sodium lauryl sulfate and 100 percent of kaolin are supplemented, put into a stirrer to be uniformly stirred and then are crushed by air flow to obtain the quinoline calcium with the concentration of 50 percent WP.
Claims (12)
1. Use of a compound of the following formula a for plant disease control, the compound of the formula a having the following formula:
wherein the plant disease is one or more of plant fungal disease, plant bacterial disease or plant auxotrophy caused by calcium deficiency.
2. Use according to claim 1, characterized in that the plant diseases are plant fungal diseases and plant auxotrophies due to calcium deficiency.
3. Use according to claim 1, characterized in that the plant diseases are plant bacterial diseases and plant auxotrophies caused by calcium deficiency.
4. Use according to any one of claims 1 to 3, characterized in that the plant is a crop selected from any one of the group consisting of cereals, fruit trees, vegetables, sugar plants, oil crops, tobacco or tea trees.
5. Use according to any one of claims 1 to 3, characterized in that the plant disease is rice bacterial blight, rice basal rot, cucumber angular leaf spot, tomato early blight, rice bacterial leaf streak, tomato late blight, apple alternaria leaf spot, grape downy mildew or peach bacterial blight.
6. Use according to any one of claims 1 to 3, characterized in that the effective amount of the compound of formula A for controlling plant diseases is from 15 to 1500 g/ha, preferably the effective amount of the compound of formula A for controlling plant diseases is from 100 g/ha to 500 g/ha.
7. A pharmaceutical composition for controlling plant diseases, which comprises a compound of the following formula A and agriculturally, forestry or hygienically acceptable adjuvants and carriers,
wherein the weight of the compound with the chemical formula A accounts for 1-99% of the weight of the pharmaceutical composition, and the sum of the weight of the auxiliary agent and the carrier accounts for 1-99% of the weight of the pharmaceutical composition.
8. The pharmaceutical composition for controlling plant diseases according to claim 7, characterized in that the pharmaceutical composition is in the form of a suspension, a suspoemulsion, an aqueous dispersion granule or a wettable powder.
9. Use of the pharmaceutical composition according to any one of claims 7 to 8 for controlling plant diseases, characterized in that the plant diseases are one or more of fungal diseases, bacterial diseases or auxotrophic diseases of plants.
10. The use as claimed in claim 9, characterized in that the pharmaceutical composition contains the compound of the formula A in an amount of 20 to 60% by weight, and the dilution factor at the time of administration is 100-4000 times.
11. Use according to claim 9, characterized in that the plant disease is rice bacterial blight, rice basal rot, cucumber angular leaf spot, tomato early blight, rice bacterial leaf streak or tomato late blight.
12. A method for controlling plant diseases by using the pharmaceutical composition according to claim 7 or 8, characterized in that the pharmaceutical composition is applied to plants to be controlled for diseases or to a medium to be controlled for harmful bacteria or fungi at an effective dose of 15 g to 1500g of calcium quinolinate per hectare, preferably, the pharmaceutical composition is applied to plants to be controlled for diseases or to a medium to be controlled for harmful bacteria or fungi at an effective dose of 100 g to 500g of calcium quinolinate per hectare.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810699172.0A CN110651791B (en) | 2018-06-29 | 2018-06-29 | Application of calcium quinolinate in preventing and treating plant diseases and composition thereof |
| PCT/CN2019/091982 WO2020001352A1 (en) | 2018-06-29 | 2019-06-20 | Use of calcium quinoline for preventing a plant disease and a composition of calcium quinoline |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810699172.0A CN110651791B (en) | 2018-06-29 | 2018-06-29 | Application of calcium quinolinate in preventing and treating plant diseases and composition thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110651791A true CN110651791A (en) | 2020-01-07 |
| CN110651791B CN110651791B (en) | 2023-08-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810699172.0A Active CN110651791B (en) | 2018-06-29 | 2018-06-29 | Application of calcium quinolinate in preventing and treating plant diseases and composition thereof |
Country Status (2)
| Country | Link |
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| CN (1) | CN110651791B (en) |
| WO (1) | WO2020001352A1 (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6097904A (en) * | 1983-11-03 | 1985-05-31 | Showa Electric Wire & Cable Co Ltd | Agent for preventing termite |
| JPS60115503A (en) * | 1983-11-25 | 1985-06-22 | Showa Electric Wire & Cable Co Ltd | Termite destroying agent |
| JPS63238004A (en) * | 1987-03-25 | 1988-10-04 | Showa Electric Wire & Cable Co Ltd | Termite-controlling material |
| CN105348191A (en) * | 2015-11-30 | 2016-02-24 | 南昌航空大学 | Method for directly preparing pure 8-quinolinol calcium |
| CN105439950A (en) * | 2015-12-26 | 2016-03-30 | 南昌航空大学 | Method for preparing luminescent material 8-hydroxyquinoline calcium |
-
2018
- 2018-06-29 CN CN201810699172.0A patent/CN110651791B/en active Active
-
2019
- 2019-06-20 WO PCT/CN2019/091982 patent/WO2020001352A1/en active Application Filing
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6097904A (en) * | 1983-11-03 | 1985-05-31 | Showa Electric Wire & Cable Co Ltd | Agent for preventing termite |
| JPS60115503A (en) * | 1983-11-25 | 1985-06-22 | Showa Electric Wire & Cable Co Ltd | Termite destroying agent |
| JPS63238004A (en) * | 1987-03-25 | 1988-10-04 | Showa Electric Wire & Cable Co Ltd | Termite-controlling material |
| CN105348191A (en) * | 2015-11-30 | 2016-02-24 | 南昌航空大学 | Method for directly preparing pure 8-quinolinol calcium |
| CN105439950A (en) * | 2015-12-26 | 2016-03-30 | 南昌航空大学 | Method for preparing luminescent material 8-hydroxyquinoline calcium |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110651791B (en) | 2023-08-15 |
| WO2020001352A1 (en) | 2020-01-02 |
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