CN110648894B - 用于电离样品的质谱分析探针和系统 - Google Patents
用于电离样品的质谱分析探针和系统 Download PDFInfo
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- CN110648894B CN110648894B CN201910835375.2A CN201910835375A CN110648894B CN 110648894 B CN110648894 B CN 110648894B CN 201910835375 A CN201910835375 A CN 201910835375A CN 110648894 B CN110648894 B CN 110648894B
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- mass spectrometry
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- spectrometry probe
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
- H01J49/165—Electrospray ionisation
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0409—Sample holders or containers
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K1/00—Printed circuits
- H05K1/18—Printed circuits structurally associated with non-printed electric components
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0013—Miniaturised spectrometers, e.g. having smaller than usual scale, integrated conventional components
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- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Plasma & Fusion (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN6137/CHE/2013 | 2013-12-30 | ||
| IN6137CH2013 | 2013-12-30 | ||
| US201461926713P | 2014-01-13 | 2014-01-13 | |
| US61/926,713 | 2014-01-13 | ||
| PCT/US2014/071856 WO2015100221A2 (en) | 2013-12-28 | 2014-12-22 | Mass spectrometry probes and systems for ionizing a sample |
| CN201480076440.3A CN106102873B (zh) | 2013-12-30 | 2014-12-22 | 用于电离样品的质谱分析探针和系统 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480076440.3A Division CN106102873B (zh) | 2013-12-30 | 2014-12-22 | 用于电离样品的质谱分析探针和系统 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110648894A CN110648894A (zh) | 2020-01-03 |
| CN110648894B true CN110648894B (zh) | 2022-05-13 |
Family
ID=53479776
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910835375.2A Active CN110648894B (zh) | 2013-12-30 | 2014-12-22 | 用于电离样品的质谱分析探针和系统 |
| CN201480076440.3A Active CN106102873B (zh) | 2013-12-30 | 2014-12-22 | 用于电离样品的质谱分析探针和系统 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480076440.3A Active CN106102873B (zh) | 2013-12-30 | 2014-12-22 | 用于电离样品的质谱分析探针和系统 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US10395913B2 (enExample) |
| EP (2) | EP3667701A3 (enExample) |
| JP (2) | JP6577950B2 (enExample) |
| CN (2) | CN110648894B (enExample) |
| WO (1) | WO2015100221A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8207497B2 (en) | 2009-05-08 | 2012-06-26 | Ionsense, Inc. | Sampling of confined spaces |
| US8822949B2 (en) | 2011-02-05 | 2014-09-02 | Ionsense Inc. | Apparatus and method for thermal assisted desorption ionization systems |
| WO2013184320A1 (en) | 2012-06-06 | 2013-12-12 | Purdue Research Foundation | Ion focusing |
| US9620344B2 (en) * | 2013-06-25 | 2017-04-11 | Purdue Research Foundation | Mass spectrometry analysis of microorganisms in samples |
| US9337007B2 (en) | 2014-06-15 | 2016-05-10 | Ionsense, Inc. | Apparatus and method for generating chemical signatures using differential desorption |
| US10656157B2 (en) | 2014-09-24 | 2020-05-19 | Purdue Research Foundation | Rare event detection using mass tags |
| JP6631132B2 (ja) * | 2015-09-30 | 2020-01-15 | 東ソー株式会社 | イオン化合物のイオン変換方法及びイオン変換装置 |
| US9899196B1 (en) | 2016-01-12 | 2018-02-20 | Jeol Usa, Inc. | Dopant-assisted direct analysis in real time mass spectrometry |
| SG11201901866TA (en) * | 2016-09-02 | 2019-03-28 | Univ Texas | Collection probe and methods for the use thereof |
| US10056218B1 (en) | 2017-02-17 | 2018-08-21 | Savannah River Nuclear Solutions, Llc | Graphene/graphite-based filament for thermal ionization |
| US10636640B2 (en) | 2017-07-06 | 2020-04-28 | Ionsense, Inc. | Apparatus and method for chemical phase sampling analysis |
| WO2019104328A1 (en) | 2017-11-27 | 2019-05-31 | Board Of Regents, The University Of Texas System | Minimally invasive collection probe and methods for the use thereof |
| WO2019231859A1 (en) | 2018-06-01 | 2019-12-05 | Ionsense Inc. | Apparatus and method for reducing matrix effects when ionizing a sample |
| US11264228B2 (en) | 2018-10-09 | 2022-03-01 | Savannah River Nuclear Solutions, Llc | Method of making a carbon filament for thermal ionization |
| CN109187713B (zh) * | 2018-10-17 | 2020-12-22 | 湖南师范大学 | 负载纸基、其制备方法和离子源及其应用 |
| WO2020154477A1 (en) | 2019-01-25 | 2020-07-30 | Board Of Regents, The University Of Texas System | Apparatus and methods for cleaning and/or exchanging medical devices |
| US11424116B2 (en) | 2019-10-28 | 2022-08-23 | Ionsense, Inc. | Pulsatile flow atmospheric real time ionization |
| US11913861B2 (en) | 2020-05-26 | 2024-02-27 | Bruker Scientific Llc | Electrostatic loading of powder samples for ionization |
| US12390811B1 (en) * | 2020-06-17 | 2025-08-19 | The United States Of America, As Represented By The Secretary Of The Navy | Sampling platform apparatus |
| US11635353B2 (en) * | 2020-06-17 | 2023-04-25 | The United States Of America, As Represented By The Secretary Of The Navy | Sample collection device |
| US12409451B1 (en) * | 2020-06-17 | 2025-09-09 | The United States Of America, As Represented By The Secretary Of The Navy | Sampling platform system |
| US11688596B2 (en) | 2021-02-12 | 2023-06-27 | Lawrence Livermore National Security, Llc | Systems and methods lattice spray substrates for mass spectrometry |
| CN113109416B (zh) * | 2021-04-20 | 2022-06-14 | 清华大学 | 一种激素的快速高通量质谱检测装置及方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005104179A2 (en) * | 2004-04-27 | 2005-11-03 | Koninklijke Philips Electronics N.V. | Use of carbon nanotubes (cnts) for analysis of samples |
| CN102414778A (zh) * | 2009-04-30 | 2012-04-11 | 普度研究基金会 | 使用潮湿的多孔材料产生离子 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4663230A (en) | 1984-12-06 | 1987-05-05 | Hyperion Catalysis International, Inc. | Carbon fibrils, method for producing same and compositions containing same |
| US6452167B1 (en) * | 1998-05-20 | 2002-09-17 | Sandia National Laboratories | Miniature quadrupole mass spectrometer having a cold cathode ionization source |
| CA2301451A1 (en) | 2000-03-20 | 2001-09-21 | Thang T. Pham | Method for analysis of analytes by mass spectrometry |
| US7368708B2 (en) * | 2000-05-25 | 2008-05-06 | Agilent Technologies, Inc. | Apparatus for producing ions from an electrospray assembly |
| US6803568B2 (en) * | 2001-09-19 | 2004-10-12 | Predicant Biosciences, Inc. | Multi-channel microfluidic chip for electrospray ionization |
| US6958475B1 (en) * | 2003-01-09 | 2005-10-25 | Colby Steven M | Electron source |
| US7579077B2 (en) * | 2003-05-05 | 2009-08-25 | Nanosys, Inc. | Nanofiber surfaces for use in enhanced surface area applications |
| US6891156B2 (en) | 2003-04-30 | 2005-05-10 | Perkin Elmer Instruments Llc | Sample plate for matrix-assisted laser desorption and ionization mass spectrometry |
| US6885010B1 (en) * | 2003-11-12 | 2005-04-26 | Thermo Electron Corporation | Carbon nanotube electron ionization sources |
| JP4370510B2 (ja) * | 2003-12-25 | 2009-11-25 | 努 升島 | 質量分析用エレクトロスプレーイオン化ノズル |
| EP1913800A4 (en) * | 2005-07-27 | 2016-09-21 | Wisconsin Alumni Res Found | NANOELECTROMECHANICAL AND MICROELECTROMECHANICAL SENSORS AND ANALYZERS |
| US20070272852A1 (en) * | 2006-01-26 | 2007-11-29 | Sionex Corporation | Differential mobility spectrometer analyzer and pre-filter apparatus, methods, and systems |
| US7884359B2 (en) * | 2006-06-09 | 2011-02-08 | The United States Of America As Represented By The Secretary Of The Navy | Integrally gated carbon nanotube ionizer device |
| WO2008103733A2 (en) * | 2007-02-20 | 2008-08-28 | Applied Nanotech, Inc. | Gas ionizer |
| WO2009023361A2 (en) | 2007-06-01 | 2009-02-19 | Purdue Research Foundation | Discontinuous atmospheric pressure interface |
| US20120160997A1 (en) * | 2007-09-21 | 2012-06-28 | Richard Lee Fink | Non-radioactive ion sources with ion flow control |
| KR101094453B1 (ko) * | 2009-06-11 | 2011-12-15 | 고려대학교 산학협력단 | 전자 방출원의 제조방법 및 이를 적용한 전자소자의 제조방법 |
| US8841454B2 (en) * | 2009-07-17 | 2014-09-23 | Exxonmobil Research And Engineering Company | Functionalized carbon nanostructures which are soluble in hydrocarbons and method for preparation |
| US8207496B2 (en) * | 2010-02-05 | 2012-06-26 | Thermo Finnigan Llc | Multi-needle multi-parallel nanospray ionization source for mass spectrometry |
| US20110223085A1 (en) * | 2010-03-12 | 2011-09-15 | E. I. Du Pont De Nemours And Company | Carbon dioxide capture with ionic liquid electrospray |
| WO2012094227A2 (en) | 2011-01-05 | 2012-07-12 | Purdue Research Foundation (Prf) | Systems and methods for sample analysis |
| US8895918B2 (en) * | 2011-06-03 | 2014-11-25 | Purdue Research Foundation | Ion generation using modified wetted porous materials |
| WO2012170301A1 (en) | 2011-06-04 | 2012-12-13 | Purdue Research Foundation (Prf) | Cassettes, systems, and methods for ion generation using wetted porous materials |
| JP5771458B2 (ja) * | 2011-06-27 | 2015-09-02 | 株式会社日立ハイテクノロジーズ | 質量分析装置及び質量分析方法 |
| CN102324375B (zh) * | 2011-07-22 | 2013-12-04 | 中国科学院上海有机化学研究所 | 一种质谱纳喷雾电极及其制作方法和应用 |
| CN102522311A (zh) * | 2011-10-20 | 2012-06-27 | 中国科学院上海有机化学研究所 | 一种纳喷雾电极及其制作方法和应用 |
| US9733228B2 (en) * | 2013-01-31 | 2017-08-15 | Purdue Research Foundation | Methods of analyzing crude oil |
-
2014
- 2014-12-22 EP EP19206323.8A patent/EP3667701A3/en not_active Withdrawn
- 2014-12-22 EP EP14875647.1A patent/EP3089811B1/en active Active
- 2014-12-22 JP JP2016543047A patent/JP6577950B2/ja active Active
- 2014-12-22 WO PCT/US2014/071856 patent/WO2015100221A2/en not_active Ceased
- 2014-12-22 US US15/104,405 patent/US10395913B2/en active Active
- 2014-12-22 CN CN201910835375.2A patent/CN110648894B/zh active Active
- 2014-12-22 CN CN201480076440.3A patent/CN106102873B/zh active Active
-
2019
- 2019-07-19 US US16/516,823 patent/US10559455B2/en active Active
-
2020
- 2020-01-02 US US16/732,568 patent/US10991564B2/en active Active
-
2021
- 2021-09-16 JP JP2021151100A patent/JP2022002214A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005104179A2 (en) * | 2004-04-27 | 2005-11-03 | Koninklijke Philips Electronics N.V. | Use of carbon nanotubes (cnts) for analysis of samples |
| CN102414778A (zh) * | 2009-04-30 | 2012-04-11 | 普度研究基金会 | 使用潮湿的多孔材料产生离子 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106102873A (zh) | 2016-11-09 |
| US10395913B2 (en) | 2019-08-27 |
| US10559455B2 (en) | 2020-02-11 |
| WO2015100221A2 (en) | 2015-07-02 |
| EP3667701A2 (en) | 2020-06-17 |
| EP3089811B1 (en) | 2019-11-06 |
| JP6577950B2 (ja) | 2019-09-18 |
| WO2015100221A3 (en) | 2015-12-17 |
| EP3667701A3 (en) | 2020-07-29 |
| JP2017502467A (ja) | 2017-01-19 |
| US20160314956A1 (en) | 2016-10-27 |
| CN110648894A (zh) | 2020-01-03 |
| US20190355567A1 (en) | 2019-11-21 |
| US20200168446A1 (en) | 2020-05-28 |
| US10991564B2 (en) | 2021-04-27 |
| CN106102873B (zh) | 2019-09-24 |
| EP3089811A2 (en) | 2016-11-09 |
| EP3089811A4 (en) | 2017-07-26 |
| JP2022002214A (ja) | 2022-01-06 |
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