CN110604130A - Freezing pole that carries - Google Patents
Freezing pole that carries Download PDFInfo
- Publication number
- CN110604130A CN110604130A CN201911047737.8A CN201911047737A CN110604130A CN 110604130 A CN110604130 A CN 110604130A CN 201911047737 A CN201911047737 A CN 201911047737A CN 110604130 A CN110604130 A CN 110604130A
- Authority
- CN
- China
- Prior art keywords
- slide
- sleeve
- embryo
- freezing
- handle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
- A01N1/0268—Carriers for immersion in cryogenic fluid, both for slow-freezing and vitrification, e.g. open or closed "straws" for embryos, oocytes or semen
Abstract
The invention relates to the technical field of medical instruments, in particular to a freezing carrying rod. It comprises a carrying rod and a sleeve; the slide rod comprises a handle and a slide arranged at the front end of the handle, and a latticed bearing area is arranged on the slide; one end of the sleeve is open and the other end is closed, and the open end of the sleeve is sleeved at the front end of the handle. According to the invention, the grid-shaped bearing area is arranged on the glass slide, when gametes or embryo liquid drops are dripped in the bearing area, the gametes/embryos can be stably adsorbed on the bearing area, so that the adsorption performance of the glass slide is improved, the gametes/embryo liquid drops can be well fixed during freezing, and the risk that the gametes/embryo liquid drops fall off is avoided; the grid structure can ensure that the embryo is fully contacted with liquid nitrogen, so that the embryo has higher freezing rate; when unfreezing, the grid structure can reduce the contact area of gametes/embryos and the surface of the glass slide, is beneficial to the gametes/embryos to fall off, can ensure that the embryos are in full contact with unfreezing liquid, and has higher unfreezing speed.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a freezing carrying rod.
Background
Assisted reproduction is a short-term assisted reproduction technology for human beings, and refers to a technology for making sterile couples pregnant by adopting medical auxiliary means, and comprises two major technologies of artificial insemination, in vitro fertilization-embryo transplantation and derivation. In the IVF-embryo transfer technique (also called tube transfer technique), various auxiliary reproductive specimens such as sperm and ovum in vitro fertilization operation, embryo transfer operation, and freezing and recovering work of embryo can be checked by a special IVF system check mode.
The cryopreservation of gametes/embryos in the field of assisted reproduction provides a wider choice for sterile patients, and the cryopreservation of gametes/embryos becomes one of indispensable technologies in assisted reproduction technology; in the process of cryopreservation of gametes/embryos, the gametes/embryos are usually cryopreserved by using a freezing carrying rod as a carrier.
At present, in the process of unfreezing embryos, the phenomenon that the embryos are stuck on a carrying rod and are not easy to fall off often occurs, and the embryos have to be taken down by other tools due to the limitation of strict unfreezing time, so that the embryos are likely to be damaged, and even fall off from a zona pellucida occurs; the carrier on the original carrying rod is a glass slide, the embryo can be in a spherical shape in the using process, the embryo is not beneficial to absorbing the freezing liquid around the embryo, meanwhile, the freezing and the unfreezing both need longer time, and the quality of the embryo is easily influenced.
Disclosure of Invention
In view of the above-mentioned shortcomings of the prior art, it is an object of the present invention to provide a freezing bar.
In order to achieve the purpose, the invention adopts the following technical scheme:
a freezing carrier bar comprises a carrier bar and a sleeve; the slide rod comprises a handle and a slide arranged at the front end of the handle, and a grid-shaped bearing area is formed on the slide; one end of the sleeve is open, the other end of the sleeve is closed, and the open end of the sleeve is sleeved at the front end of the handle.
Preferably, the carrier region is disposed at a front end of the slide.
Preferably, black identification points are arranged at the front end of the slide, and the identification points are distributed on the front side of the bearing area.
Preferably, the front end and the rear end of the handle are respectively provided with a supporting block.
Preferably, the cross section of the supporting block is of a square structure and is formed by extending outwards from the peripheral wall of the handle.
Preferably, the support block is provided with a marking area for writing a mark.
Preferably, the front end of the handle is provided with a connecting section in a cone structure, and the slide is arranged at the front end of the connecting section; the open end of sleeve sets up to the horn structure with linking up section complex, the open end and the linking up section interference fit of sleeve.
Preferably, the closed end of the sleeve is provided with a steel ring.
By adopting the scheme, the grid-shaped bearing area is arranged on the glass slide and is used for bearing gamete/embryo liquid drops, when the gamete/embryo liquid drops are dripped into the grid-shaped bearing area, the gamete/embryo can be stably adsorbed on the bearing area, the adsorption performance of the glass slide is improved, and during freezing, the gamete/embryo liquid drops can be well fixed due to the grid structure on the surface of the bearing area, so that the risk that the gamete/embryo liquid drops fall off is avoided; when the gametes/embryos are frozen, gametes or embryo liquid drops are uniformly distributed in the latticed bearing area to provide a larger contact area for the gametes/embryos and liquid nitrogen, and compared with a planar structure, the latticed structure can enable the embryos to be in full contact with the liquid nitrogen, so that the embryos have a higher freezing rate; when the gamete/embryo is unfrozen, the grid structure can reduce the contact area of the gamete/embryo and the surface of the glass slide, and is favorable for the gamete/embryo to fall off.
Based on the structure, the structure is simple and compact, and the grid-shaped bearing area is arranged on the glass slide, so that a larger contact area is provided for the embryo and liquid nitrogen/unfreezing liquid, and the embryo has higher freezing/unfreezing speed; meanwhile, the contact area between the embryo and the glass slide is reduced, and the embryo can fall off from the freezing carrying rod quickly, so that the method has strong practical value and market popularization value.
Drawings
FIG. 1 is a schematic structural diagram of an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of an embodiment of the present invention;
fig. 3 is a schematic structural diagram of a carrier bar according to an embodiment of the present invention.
Detailed Description
The embodiments of the invention will be described in detail below with reference to the drawings, but the invention can be implemented in many different ways as defined and covered by the claims.
As shown in fig. 1 to 3, the embodiment of the present invention provides a freezing bar, which comprises a bar and a sleeve 20; the slide rod comprises a handle 11 and a slide 12 arranged at the front end of the handle 11, a grid-shaped bearing area 121 is arranged on the slide 12, and the bearing area 121 is preferably arranged at the front end side of the slide 12; the sleeve 20 is open at one end and closed at the other end, and the open end of the sleeve 20 is adapted to be fitted over the front end of the handle 11 to enclose the slide 12 inside the sleeve 20. Therefore, the grid-shaped bearing area 121 is arranged on the slide 12 and is used for bearing gamete/embryo liquid drops, when gametes or embryo liquid drops are dripped in the grid-shaped bearing area 121, the gametes/embryos can be stably adsorbed on the bearing area 121, the adsorption performance of the slide 12 is improved, and during freezing, the gametes/embryo liquid drops can be well fixed due to the grid structure on the surface of the bearing area 121, so that the risk that the gametes/embryo liquid drops fall off is avoided; when gametes/embryos are frozen, gametes or embryo liquid drops are uniformly distributed in the latticed bearing area 121, a larger contact area is provided for the gametes/embryos and liquid nitrogen, and compared with a planar structure, the latticed structure can enable the embryos to be in full contact with the liquid nitrogen, so that the embryos have a higher freezing rate; when the gamete/embryo is unfrozen, the contact area of the gamete/embryo and the surface of the glass slide 12 can be reduced by the grid structure, the gamete/embryo can fall off favorably, for example, by shaking the freezing carrying rod, unfreezing liquid can penetrate through the grid, the gamete/embryo can be blown off from the carrying rod more favorably, compared with a plane structure, the grid structure can enable the embryo to be in full contact with the unfreezing liquid, the unfreezing speed is higher, and the unfreezing of the embryo is more favorably realized.
Based on the structure, the structure is simple and compact, and the grid-shaped bearing area is arranged on the glass slide, so that a larger contact area is provided for the embryo and liquid nitrogen/unfreezing liquid, and the embryo has higher freezing/unfreezing speed; meanwhile, the contact area between the embryo and the glass slide is reduced, and the embryo can fall off from the freezing carrying rod quickly, so that the method has strong practical value and market popularization value.
Further, as a specific embodiment of the freezing slide bar provided in this embodiment, referring to fig. 3, the front end of the slide 12 is provided with black mark points 122, and the mark points 122 are distributed on the front side of the carrying area 121. By identifying the points 122, it is advantageous to clearly identify the position of the slide 12 in the liquid nitrogen.
As a specific embodiment of the freezing bar of the present embodiment, please refer to fig. 1-3, the front and rear ends of the handle 11 are respectively provided with a supporting block 111. Through the supporting blocks 111 at the two ends of the handle 11, the freezing loading rod can be horizontally placed on the microscope by adopting a placing method except for experimental operation in a handheld mode, so that the front end of the freezing loading rod is prevented from contacting with an operating table, and the freezing loading rod has better stability.
Further, as a specific embodiment of the freezing loading bar provided in this embodiment, referring to fig. 1-3, the cross section of the supporting block 111 is a square structure and is formed by extending outward from the peripheral wall of the handle 11. The supporting blocks 111 with the square structures form square structures, so that the stability of placing the freezing loading rod is improved conveniently, and a stable placing mode is provided for the freezing loading rod.
Further, as a specific embodiment of the freezing loading rod provided in this embodiment, the supporting block 111 is provided with a marking area (not shown) for writing marks. The marking area on the supporting block 111 is used for facilitating the writing of marks and identifying different gamete/embryo samples.
As a specific embodiment of the freezing slide bar provided in this embodiment, please refer to fig. 1-3, the front end of the handle 11 is provided with a connecting section 13 in a cone structure, and the slide 12 is installed at the front end of the connecting section 13; the open end of the sleeve 20 is arranged to be a horn-shaped structure matched with the engagement section 13, and the open end of the sleeve 20 is in interference fit with the engagement section 13. The connecting section 13 at the front end of the sleeve 20 and the handle 11 adopts a horn-type connecting mode, when the carrying rod is inserted into the sleeve 20, the connecting section 13 and the open end of the sleeve 20 form interference fit, so that the sealing effect between the carrying rod and the sleeve 20 is better, the gamete/embryo is sealed in the sleeve 20, and the gamete/embryo is prevented from being polluted in the freezing process.
As a specific embodiment of the freezing bar of this embodiment, please refer to fig. 1 and 2, the closed end of the sleeve 20 is provided with a steel ring 21. Under the effect of steel ring 21, carry the front end of pole and can sink into in the liquid nitrogen fast, make and carry the pole and fully contact with the liquid nitrogen, avoid floating, be favorable to freezing the save.
The above description is only a preferred embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, which are made by using the contents of the present specification and the accompanying drawings, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.
Claims (8)
1. A frozen bar, comprising: it comprises a carrying rod and a sleeve; the slide rod comprises a handle and a slide arranged at the front end of the handle, and a grid-shaped bearing area is formed on the slide; one end of the sleeve is open, the other end of the sleeve is closed, and the open end of the sleeve is sleeved at the front end of the handle.
2. A freezing bar as claimed in claim 1, wherein: the bearing area is arranged at the front end of the slide.
3. A freezing bar as claimed in claim 1, wherein: the front end of the glass slide is provided with black identification points, and the identification points are distributed on the front side of the bearing area.
4. A freezing bar as claimed in claim 1, wherein: the front end and the rear end of the handle are respectively provided with a supporting block.
5. A freezing bar as claimed in claim 4 wherein: the section of the supporting block is of a square structure and is formed by extending the peripheral wall of the handle outwards.
6. A freezing bar as claimed in claim 4 wherein: the supporting block is provided with a marking area for writing marks.
7. A freezing bar as claimed in claim 1, wherein: the front end of the handle is provided with a connecting section in a cone structure, and the slide is arranged at the front end of the connecting section; the open end of sleeve sets up to the horn structure with linking up section complex, the open end and the linking up section interference fit of sleeve.
8. A freezing bar as claimed in claim 1, wherein: the closed end of the sleeve is provided with a steel ring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911047737.8A CN110604130A (en) | 2019-10-30 | 2019-10-30 | Freezing pole that carries |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911047737.8A CN110604130A (en) | 2019-10-30 | 2019-10-30 | Freezing pole that carries |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110604130A true CN110604130A (en) | 2019-12-24 |
Family
ID=68895549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911047737.8A Withdrawn CN110604130A (en) | 2019-10-30 | 2019-10-30 | Freezing pole that carries |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110604130A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113412832A (en) * | 2020-12-30 | 2021-09-21 | 上海明悦医疗科技有限公司 | Freezing carrying rod and manufacturing method thereof |
| CN113615678A (en) * | 2021-06-24 | 2021-11-09 | 上海市第一妇婴保健院 | Carrier bar body, freezing carrier bar and manufacturing method of carrier bar body |
| CN115486437A (en) * | 2021-06-18 | 2022-12-20 | 上海明悦医疗科技有限公司 | Auxiliary reproduction carrier bar assembly |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101779623A (en) * | 2010-03-11 | 2010-07-21 | 中国农业大学 | Cryopreservation method for oocyte / embryo and frozen carrier thereof |
| WO2011070973A1 (en) * | 2009-12-08 | 2011-06-16 | 学校法人北里研究所 | Narrow tube for vitrification preservation of animal embryo or ovum |
| CN205005790U (en) * | 2015-08-25 | 2016-02-03 | 柳州市妇幼保健院 | Novel freezing pole that carries of embryo's glass ization |
| CN106489914A (en) * | 2016-10-20 | 2017-03-15 | 北京中仪康卫医疗器械有限公司 | A kind of freezing carries bar |
| CN209331001U (en) * | 2018-11-09 | 2019-09-03 | 彭秋平 | Freezing carries bar |
-
2019
- 2019-10-30 CN CN201911047737.8A patent/CN110604130A/en not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011070973A1 (en) * | 2009-12-08 | 2011-06-16 | 学校法人北里研究所 | Narrow tube for vitrification preservation of animal embryo or ovum |
| CN101779623A (en) * | 2010-03-11 | 2010-07-21 | 中国农业大学 | Cryopreservation method for oocyte / embryo and frozen carrier thereof |
| CN205005790U (en) * | 2015-08-25 | 2016-02-03 | 柳州市妇幼保健院 | Novel freezing pole that carries of embryo's glass ization |
| CN106489914A (en) * | 2016-10-20 | 2017-03-15 | 北京中仪康卫医疗器械有限公司 | A kind of freezing carries bar |
| CN209331001U (en) * | 2018-11-09 | 2019-09-03 | 彭秋平 | Freezing carries bar |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113412832A (en) * | 2020-12-30 | 2021-09-21 | 上海明悦医疗科技有限公司 | Freezing carrying rod and manufacturing method thereof |
| CN115486437A (en) * | 2021-06-18 | 2022-12-20 | 上海明悦医疗科技有限公司 | Auxiliary reproduction carrier bar assembly |
| WO2022262357A1 (en) * | 2021-06-18 | 2022-12-22 | 上海明悦医疗科技有限公司 | Assisted reproduction carrier rod assembly |
| CN115486437B (en) * | 2021-06-18 | 2024-01-23 | 上海明悦医疗科技有限公司 | Auxiliary reproduction carrying rod assembly |
| CN113615678A (en) * | 2021-06-24 | 2021-11-09 | 上海市第一妇婴保健院 | Carrier bar body, freezing carrier bar and manufacturing method of carrier bar body |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20191224 |