CN110559367A - Medicinal preparation for treating livestock diarrhea - Google Patents

Medicinal preparation for treating livestock diarrhea Download PDF

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Publication number
CN110559367A
CN110559367A CN201910803138.8A CN201910803138A CN110559367A CN 110559367 A CN110559367 A CN 110559367A CN 201910803138 A CN201910803138 A CN 201910803138A CN 110559367 A CN110559367 A CN 110559367A
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CN
China
Prior art keywords
diarrhea
livestock
treating
pharmaceutical preparation
medicinal preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910803138.8A
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Chinese (zh)
Inventor
刘成旺
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inner Mongolia Caben Animal Pharmaceutical Co Ltd
Original Assignee
Inner Mongolia Caben Animal Pharmaceutical Co Ltd
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Publication date
Application filed by Inner Mongolia Caben Animal Pharmaceutical Co Ltd filed Critical Inner Mongolia Caben Animal Pharmaceutical Co Ltd
Priority to CN201910803138.8A priority Critical patent/CN110559367A/en
Publication of CN110559367A publication Critical patent/CN110559367A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/84Valerianaceae (Valerian family), e.g. valerian
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a medicinal preparation for treating livestock diarrhea, and belongs to the technical field of medicinal preparations for livestock. The invention discloses a pharmaceutical preparation, which is prepared from the following components: 1-3g of valeriana jatamansi jones, 50-75mg of enrofloxacin, 0.5g of synergist and 10g of excipient. The medicinal preparation disclosed by the invention has the characteristics of wide antibacterial spectrum and strong effect, and has the advantages of short treatment course, quick response, low price, good efficiency of treating diarrhea of young livestock, short treatment time and high cure rate, the diarrhea can be cured within 2 days generally, and the cure rate reaches more than 90%; and the components have synergistic interaction.

Description

Medicinal preparation for treating livestock diarrhea
Technical Field
The invention relates to the technical field of veterinary medicinal preparations, in particular to a medicinal preparation for treating livestock diarrhea.
Background
The livestock diarrhea is a common disease and frequently encountered disease of livestock, particularly young livestock, and the incidence rate is over 80 percent. The disease occurs mainly within 1-2 months of weaning period of young animals. As young stock grows up, the feed intake is larger and larger, the milk intake of female stock is reduced, the young stock is changed from milk eating to grass eating, and the gastrointestinal tract is easy to eat pathogenic bacteria in the transformation of digestive function to cause gastrointestinal tract bacterial diseases. Especially the milk amount of the female animals is insufficient in nature, the physique of the young animals is poor, the gastrointestinal system of the young animals is underdeveloped, the grass is eaten too early, and the environmental sanitation is poor. Secondly, the method comprises the following steps: inflammation is caused by postpartum dams. Because newborn young animals have no resistance by themselves, all resistance is taken in colostrum after birth, and if the breast milk is unhealthy, the young animals eat the breast milk produced by female animals with inflammation, so that diarrhea diseases of the young animals can occur. Young animals die annually due to diarrhea account for about 10%. There are currently a number of drugs that treat this disease. But still is one of the diseases with highest morbidity and mortality of young stock, which seriously impedes the development of animal husbandry and causes huge economic loss.
Therefore, it is a problem to be solved by those skilled in the art to provide a pharmaceutical preparation for the treatment of diarrhea in livestock.
Disclosure of Invention
In view of the above, the invention provides a pharmaceutical preparation for treating livestock diarrhea, which is prepared by combining Chinese medicines and western medicines, and has the effects of low cost, good effect of treating livestock diarrhea and high cure rate.
In order to achieve the purpose, the invention adopts the following technical scheme:
A pharmaceutical preparation for treating livestock diarrhea is prepared from the following components: 1-3g of valeriana jatamansi jones, 50-75mg of enrofloxacin, 0.5g of synergist and 10g of excipient.
The valeriana jatamansi jones is a Chinese herbal medicine and has the effects of promoting qi circulation, dispelling cold, promoting blood circulation, tranquilizing mind, promoting digestion, invigorating stomach, stopping water discharge, regulating qi-flowing and relieving pain; the traditional Chinese medicine is mainly used for treating: eruptive disease, abdominal pain, emesis, diarrhea, pulmonary edema, wind-cold type common cold, menoxenia, tuberculosis cough, dyspepsia, stomach qi pain, malnutritional stagnation, dysentery, influenza, etc.
Enrofloxacin is a chemical drug, is a special broad-spectrum bactericide for animals, and has strong killing effect on various gram-negative bacteria and gram-positive bacteria; such as Escherichia coli, Klebsiella, Salmonella, Proteus, Pseudomonas aeruginosa, Haemophilus, Pasteurella multocida, Pasteurella hemolyticus, Staphylococcus aureus, and Streptococcus; it also has good effect on mycoplasma and chlamydia.
Further, the synergist is dysentery stopping medicine such as montmorillonite.
Further, the excipient is starch or glucose.
further, the pharmaceutical preparation can be used as a stomachache and abdominal distension agent, a wind-cold type common cold agent or a cough agent.
Further, the livestock is cattle, sheep, pigs, poultry, and young cattle, sheep, pigs, poultry (calves, lambs, piglets, and chicks).
The pharmaceutical preparation of the invention is used for treating livestock digestive tract infectious diseases caused by sensitive bacteria infection, and the clinical manifestations are as follows: diarrhea, dyspnea, etc. Individual severers also manifest dehydration and neurological symptoms such as: calf-pulled cement-like foul odor and loose feces; lambs have yellow, green, yellow-white or grey-white color when the backs of the lambs are low and do not eat or the lambs are foul and loose, blood is carried in the later period, abdominal distension exists but do not pull, the sick lambs die due to the fact that weak dehydration occurs to neurological symptoms, and undigested milk lumps or food masses exist in the stomach after dissection; yellow and white scour of piglets and cement-like loose stool; pullorum disease, navel inflammation, vitellinia, dyspnea, etc.
Specifically, when the medicinal preparation is used, the medicinal preparation is orally taken by livestock, 1g of the medicinal preparation is used per kilogram of body weight, and the medicine is taken 1 to 2 times a day; wherein: the calf is drenched with 10-20g each time for 1-2 times daily; the lamb and the piglet are irrigated with 5-10g of the traditional Chinese medicine composition every time, and the traditional Chinese medicine composition is irrigated 1-2 times a day; 10g of chicks are mixed with 10 kg of feed for free feeding for 3-5 days continuously.
According to the technical scheme, compared with the prior art, the invention discloses a medicinal preparation for treating livestock diarrhea, which has the characteristics of wide antibacterial spectrum and strong effect, and has the advantages of short treatment course, quick response, low price, good treatment efficiency for treating young livestock diarrhea, short treatment time and high cure rate, the young livestock diarrhea can be cured within 2 days generally, and the cure rate reaches over 90 percent; and the components have synergistic interaction.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A pharmaceutical preparation for treating livestock diarrhea is prepared from the following components: 1g of valeriana jatamansi jones, 50mg of enrofloxacin, 0.5g of montmorillonite and 10g of starch in total.
Example 2
A pharmaceutical preparation for treating livestock diarrhea is prepared from the following components: 2g of valeriana jatamansi jones, 50mg of enrofloxacin, 0.5g of montmorillonite and 10g of starch in total.
Example 3
A pharmaceutical preparation for treating livestock diarrhea is prepared from the following components: 3g of valeriana jatamansi jones, 50mg of enrofloxacin, 0.5g of montmorillonite and 10g of glucose added in total.
Example 4
A pharmaceutical preparation for treating livestock diarrhea is prepared from the following components: 1g of valeriana jatamansi jones, 75mg of enrofloxacin, 0.5g of montmorillonite and 10g of glucose added in total.
Example 5
A pharmaceutical preparation for treating livestock diarrhea is prepared from the following components: 2g of valeriana jatamansi jones, 75mg of enrofloxacin, 0.5g of montmorillonite and 10g of starch in total.
Example 6
A pharmaceutical preparation for treating livestock diarrhea is prepared from the following components: 3g of valeriana jatamansi jones, 75mg of enrofloxacin, 0.5g of montmorillonite and 10g of glucose added in total.
The pharmaceutical preparation prepared in the examples 1-6 is fed to the calf with diarrhea, 1g of the pharmaceutical preparation is used per kilogram of body weight, and 2 times a day; the calf diarrhea is basically cured after two days.
Further verification proves that the medicinal preparation prepared in the examples 1-6 can also be used for treating stomachache and abdominal distension, wind-cold type common cold or cough and the like, and has quick response and good effect.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (5)

1. A pharmaceutical preparation for treating diarrhea in livestock is characterized by being prepared from the following components: 1-3g of valeriana jatamansi jones, 50-75mg of enrofloxacin, 0.5g of synergist and 10g of excipient.
2. The pharmaceutical preparation for treating livestock diarrhea according to claim 1, wherein said synergist is montmorillonite.
3. The pharmaceutical formulation for treating diarrhea in livestock according to claim 1, wherein said excipient is starch or glucose.
4. Pharmaceutical formulation for use in the treatment of diarrhea in livestock according to any of claims 1 to 3, characterized in that it is also usable as a stomachache-bloat, wind-cold or cough remedy.
5. The pharmaceutical preparation for the treatment of diarrhea in livestock according to any of claims 1 to 3, wherein the livestock is cattle, sheep, pigs, birds, and young cattle, sheep, pigs, birds.
CN201910803138.8A 2019-08-28 2019-08-28 Medicinal preparation for treating livestock diarrhea Pending CN110559367A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910803138.8A CN110559367A (en) 2019-08-28 2019-08-28 Medicinal preparation for treating livestock diarrhea

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Application Number Priority Date Filing Date Title
CN201910803138.8A CN110559367A (en) 2019-08-28 2019-08-28 Medicinal preparation for treating livestock diarrhea

Publications (1)

Publication Number Publication Date
CN110559367A true CN110559367A (en) 2019-12-13

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CN201910803138.8A Pending CN110559367A (en) 2019-08-28 2019-08-28 Medicinal preparation for treating livestock diarrhea

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1228304A (en) * 1999-01-14 1999-09-15 周爱敏 Antimicrobial composite
CN102846681A (en) * 2012-07-25 2013-01-02 魏艳海 Medicament for treating livestock diarrhea
CN105168242A (en) * 2015-08-24 2015-12-23 孟维宇 Oral preparation for treating bacterial intestinal diseases, preparation method and applications thereof
CN105457013A (en) * 2015-12-09 2016-04-06 成都乾坤动物药业有限公司 Pharmaceutical composition for treating diarrhea of livestock and preparation method for pharmaceutical composition
CN108113966A (en) * 2017-08-24 2018-06-05 北京中农华正兽药有限责任公司 A kind of grace stone disperses the preparation method except bitter taste

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1228304A (en) * 1999-01-14 1999-09-15 周爱敏 Antimicrobial composite
CN102846681A (en) * 2012-07-25 2013-01-02 魏艳海 Medicament for treating livestock diarrhea
CN105168242A (en) * 2015-08-24 2015-12-23 孟维宇 Oral preparation for treating bacterial intestinal diseases, preparation method and applications thereof
CN105457013A (en) * 2015-12-09 2016-04-06 成都乾坤动物药业有限公司 Pharmaceutical composition for treating diarrhea of livestock and preparation method for pharmaceutical composition
CN108113966A (en) * 2017-08-24 2018-06-05 北京中农华正兽药有限责任公司 A kind of grace stone disperses the preparation method except bitter taste

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
徐君主编: "《中药图谱 彩色图文版》", 31 May 2003, 中医古籍出版社 *
胡功政等: "《新全实用兽药手册》", 31 August 2006, 河南科学技术出版社 *

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SE01 Entry into force of request for substantive examination
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Application publication date: 20191213

RJ01 Rejection of invention patent application after publication