CN110554007A - 用于通过光检测进行定点照护凝固测定的方法及系统 - Google Patents

用于通过光检测进行定点照护凝固测定的方法及系统 Download PDF

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Publication number
CN110554007A
CN110554007A CN201910870391.5A CN201910870391A CN110554007A CN 110554007 A CN110554007 A CN 110554007A CN 201910870391 A CN201910870391 A CN 201910870391A CN 110554007 A CN110554007 A CN 110554007A
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CN
China
Prior art keywords
reaction chamber
optical
light
optical reference
excitation light
Prior art date
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Pending
Application number
CN201910870391.5A
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English (en)
Chinese (zh)
Inventor
约瑟夫·克里莫
曾寒松
罗恩·沙尔拉克
格特·布兰肯施泰因
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Werfen North America
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Instrumentation Laboratory Co
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Publication of CN110554007A publication Critical patent/CN110554007A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
    • G01N21/534—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke by measuring transmission alone, i.e. determining opacity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/063—Illuminating optical parts
    • G01N2201/0636—Reflectors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201910870391.5A 2014-04-30 2015-04-27 用于通过光检测进行定点照护凝固测定的方法及系统 Pending CN110554007A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461986475P 2014-04-30 2014-04-30
US61/986,475 2014-04-30
CN201580034415.3A CN106605144B (zh) 2014-04-30 2015-04-27 用于通过光检测进行定点照护凝固测定的方法及系统

Related Parent Applications (1)

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CN201580034415.3A Division CN106605144B (zh) 2014-04-30 2015-04-27 用于通过光检测进行定点照护凝固测定的方法及系统

Publications (1)

Publication Number Publication Date
CN110554007A true CN110554007A (zh) 2019-12-10

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CN201910870391.5A Pending CN110554007A (zh) 2014-04-30 2015-04-27 用于通过光检测进行定点照护凝固测定的方法及系统
CN201580034415.3A Active CN106605144B (zh) 2014-04-30 2015-04-27 用于通过光检测进行定点照护凝固测定的方法及系统

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Country Status (7)

Country Link
US (2) US11079325B2 (https=)
EP (1) EP3137878A1 (https=)
JP (2) JP6567549B2 (https=)
CN (2) CN110554007A (https=)
AU (1) AU2015253478C1 (https=)
CA (1) CA2946877C (https=)
WO (1) WO2015167983A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116829206A (zh) * 2020-11-13 2023-09-29 弗雷塞尼斯医疗保健控股公司 用于分析用过的透析液的系统和方法

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* Cited by examiner, † Cited by third party
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AU2015253478C1 (en) * 2014-04-30 2019-01-17 Instrumentation Laboratory Company Methods and systems for point-of-care coagulation assays by optical detection
EA033382B1 (ru) 2014-09-09 2019-10-31 Perosphere Tech Inc Универсальный анализ коагуляции на основе микрожидкостного чипа
CN115349085A (zh) * 2020-03-24 2022-11-15 前沿诊疗股份有限公司 用于常规化学、免疫分析和核酸检测的临床分光光度计
WO2022054921A1 (en) * 2020-09-11 2022-03-17 Atonarp Inc. System including auto-alignment
CN115201498A (zh) * 2021-04-13 2022-10-18 基蛋生物科技股份有限公司 一种用于凝血检测的试剂卡及检测仪器

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US20050101025A1 (en) * 2003-11-12 2005-05-12 Ho Winston Z. Apparatus for proteins and nucleic acids analysis
US20050142032A1 (en) * 2003-10-31 2005-06-30 Joachim Hoenes Test system for determining an analyte in a liquid sample
US20060110283A1 (en) * 2002-11-12 2006-05-25 Inverness Medical Switzerland Gmbh Photometric determination of coagulation time in undiluted whole blood
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US20130301051A1 (en) * 2010-06-18 2013-11-14 Andrew Pogosyan Scattering light source multi-wavelength photometer

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US5114860A (en) * 1984-10-09 1992-05-19 Toa Medical Electronics Co., Ltd. Device of measuring a blood coagulating time
US5525466A (en) * 1991-06-07 1996-06-11 Ciba Corning Diagnostics Corp. Multiple output referencing system for evanescent wave sensor
CN1301965A (zh) * 1999-12-03 2001-07-04 生命扫描有限公司 医学诊断装置的微滴分配
US20020064800A1 (en) * 2000-11-22 2002-05-30 Yasuhiro Sando Microchip
US20060110283A1 (en) * 2002-11-12 2006-05-25 Inverness Medical Switzerland Gmbh Photometric determination of coagulation time in undiluted whole blood
US20050142032A1 (en) * 2003-10-31 2005-06-30 Joachim Hoenes Test system for determining an analyte in a liquid sample
US20050101025A1 (en) * 2003-11-12 2005-05-12 Ho Winston Z. Apparatus for proteins and nucleic acids analysis
CN101010579A (zh) * 2004-07-27 2007-08-01 株式会社三菱化学药得论 被检试样的自动判别方法
CN101726477A (zh) * 2008-10-20 2010-06-09 三星电子株式会社 用于生物芯片的光学检测装置
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Publication number Priority date Publication date Assignee Title
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Publication number Publication date
EP3137878A1 (en) 2017-03-08
CA2946877A1 (en) 2015-11-05
JP2019194622A (ja) 2019-11-07
JP6567549B2 (ja) 2019-08-28
AU2015253478A1 (en) 2016-11-17
AU2015253478C1 (en) 2019-01-17
CA2946877C (en) 2021-02-09
JP2017519189A (ja) 2017-07-13
US20150316533A1 (en) 2015-11-05
CN106605144B (zh) 2019-09-27
US12571732B2 (en) 2026-03-10
US20220018765A1 (en) 2022-01-20
AU2015253478B2 (en) 2018-04-26
WO2015167983A1 (en) 2015-11-05
CN106605144A (zh) 2017-04-26
US11079325B2 (en) 2021-08-03

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Application publication date: 20191210