CN110522884A - A kind of preparation method of green grass ointment - Google Patents

A kind of preparation method of green grass ointment Download PDF

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Publication number
CN110522884A
CN110522884A CN201910781147.1A CN201910781147A CN110522884A CN 110522884 A CN110522884 A CN 110522884A CN 201910781147 A CN201910781147 A CN 201910781147A CN 110522884 A CN110522884 A CN 110522884A
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rose
ointment
honey
preparation
solid material
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崔小红
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/75—Rutaceae (Rue family)
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884—Arisaema, e.g. Jack in the pulpit
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Abstract

The present invention relates to the preparation method of green grass ointment, the preparation method includes the following steps: step 1: solid material is crushed to particle size≤5 micron by comminuted solids raw material；The solid material include the rhizoma arisaematis for accounting for ointment gross mass 2.5% to be prepared, 2.5% Radix Glycyrrhizae, 2.5% dried orange peel, 2.5% Cortex Magnoliae Officinalis, 5% rhizoma atractylodis, 15% rheum officinale, 15% root of Dahurain angelica, 15% Cortex Phellodendri, 15% turmeric and 21% radices trichosanthis；Step 2: the solid material through crushing being uniformly mixed with the rose honey wine for accounting for ointment gross mass 4% to be prepared, obtains ointment.The present invention has the advantages that green grass ointment prepared by the present invention can effectively treat bite by mosquitos, slightly sprain, cut the symptoms such as abscess caused by scald, foot pain and infectious diseases, and it is easy to be accepted by the public.

Description

A kind of preparation method of green grass ointment
Technical field
The invention belongs to pharmaceutical technology field, in particular to a kind of preparation method of green grass ointment.
Background technique
China is located in temperate zone, subtropical zone, and especially southern climates are mild, and the rainfall is plentiful, is suitble to mosquito growth and breeds, one Hurt after denier contact by them, can immediately cause toxicity, poison gas breaking-out to part, occur it is red and swollen, fever, shinny, wound without fixed place, Shaped like cloud mass, pain connects with the heart, and the swollen delayed action of pain or even fever and chills are deeply worried, once malpractice, less serious case eliminates gradually, and toxicity is hidden It to internal, severe one skin change raisin, turns black, suppurates and rot, threat to life is generally domestic for such situation, is often used wind The narcissus of olein, the brave head of cooling ointment, six minds of floral water etc.；Or by unknown bite by mosquitos, redness, erythema, it is slight sprain, Scald etc. is cut, currently, generally being matched using externally used detumescence analgesic, Yunnan Baiyao is matched, ten thousand logical grieved peaceful sprays, the drugs such as safflower oil, But these drug effect curative effects are not satisfactory.
For above-mentioned phenomenon, 106728246 A of patent CN discloses a kind of green grass ointment, and the ointment is by following weight The raw material of part is made: 30-35 parts of black bone herba fibraureae recisae, Plumbago zeylanica
20-25 parts, 10-20 parts of hot miliaria grass, pierce it is 15-20 parts grey, 5-10 parts of money peppermint, false celery 10-15 parts, ivy 5-10 Part, 3-8 parts of antibiotic, 2-6 parts of anesthetic.The green grass ointment that the invention provides can effectively treat bite by mosquitos, slightly sprain, cut The symptoms such as scald, flu and foot pain；But there are still certain defects: 1. are not applied for purulence caused by infectious diseases It is swollen；2. just starting to have when smearing with heavier mint flavored, young patient is not easily accepted by.
Therefore, bite by mosquitos can effectively be treated, slightly sprain, cut scald, foot pain and infectivity by researching and developing one kind The symptoms such as abscess caused by disease, and the preparation method for the green grass ointment for being easy to be accepted by the public is necessary.
Summary of the invention
The technical problem to be solved in the present invention is to provide one kind can effectively treat bite by mosquitos, slightly sprain, cut scald, The symptoms such as abscess caused by foot pain and infectious diseases, and the preparation method for the green grass ointment for being easy to be accepted by the public.
In order to solve the above technical problems, the technical solution of the present invention is as follows: a kind of preparation method of green grass ointment, innovative point Be: the preparation method includes the following steps:
Step 1: solid material is crushed to particle size≤5 micron by comminuted solids raw material；The solid material includes accounting for wait make Rhizoma arisaematis, 2.5% Radix Glycyrrhizae, 2.5% dried orange peel, 2.5% Cortex Magnoliae Officinalis, 5% rhizoma atractylodis, 15% of standby ointment gross mass 2.5% Rheum officinale, 15% root of Dahurain angelica, 15% Cortex Phellodendri, 15% turmeric and 21% radices trichosanthis；
Step 2: the solid material through crushing being uniformly mixed with the rose honey wine for accounting for ointment gross mass 4% to be prepared, is obtained Ointment.
Further, rose honey wine in the step 2 is through the following steps that be prepared:
The pretreatment of step a. rose: removing bennet, calyx for fresh rose, spare after cleaning, being broken；
Step b. prepares rose soak: step a spare rose is soaked in water, filtering, obtains filtrate, and as rose is soaked Steep liquid；The addition relationship of the two is rose: water=1:80 by weight；
The processing of step c. honey: weighing honey and rose soak puts into fermenter mixings, the addition relationship of the two for by Weight ratio meter, honey: rose soak=1:2；Then the saccharomyces cerevisiae of liquid total weight 1~2 ‰ is added into fermentor Ferment at 24~26 DEG C 10~15d afterwards, obtains fermentation liquid；
Step d. distillation: taking the fermentation liquid in the step c of half volume, and heating distills out height honey white wine；
Step e. fermentation, ageing: the honey white wine that step d is steamed is put into remaining fermentation liquid, is continued at 8~12 DEG C Post-fermentation to alcoholic strength reaches 8%vol or more, while ageing 1 month or more；
Step f. sterilizing: it after the completion of ageing, is sterilized using 80 DEG C of pasteurizations；
Step g. filtering: it is finally filtered using the filter method of multistage diatomite, obtains the rose honey of clear Wine.
The present invention has the advantages that
(1) preparation method of green grass ointment of the present invention, solid material select Chinese medicine herbaceous plant, then ground crushing, with Liquid rose honey wine is uniformly mixed, and prescription compatibility is rigorous, wherein solvent uses liquid rose honey wine, can either effectively extract The effective component in solid material is taken, also ointment can be made integrally to distribute light rose scent, is dissipated when avoiding ointment from smearing The taste for news of raising difficult questions, and then be easy to be accepted by the public；
Rose honey wine external application is smeared, and can prevent injury from infecting, also can swelling and pain relieving quickening wound healing；Rhizoma arisaematis can detoxify and disappear It is swollen, external curing pyogenic infections from tumour or sore, venomous snake bite, fly eradication maggot；Radix Glycyrrhizae has clearing heat and detoxicating effect；Dried orange peel can be used to beauty treatment of invigorating blood circulation, Be conducive to the health of skin, it can be with fine skin；The benefits of Cortex Magnoliae Officinalis has dampness elimination promoting, promoting the circulation of qi to relieving asthma, helping digestion dissolving phlegm, wind dispelling analgesia； Rhizoma atractylodis, Wen Xinlie bitter in taste have the benefits of turbid eliminating dampness, change, analgesic；Rheum officinale have attack stagnant, clearing away damp-heat, purging intense heat, cool blood, dissolving stasis, Removing toxic substances and other effects；The root of Dahurain angelica is warm-natured, acrid flavour, and gas fragrance, slight bitter has the effect of wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving；Cortex Phellodendri property Bitter taste is cold, returns kidney, bladder meridian, can be with heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment；Turmeric is arduous, and temperature enters spleen, Liver Channel, can manage it Gas broken stasis of blood, it is inducing meastruation to relieve menalgia；Smallpox mealiness is sweet, slight bitter, slightly cold, attaches to the lung and stomach meridians, there is clearing heat-fire, promotes the production of body fluid to quench thirst, detumescence and apocenosis Effect, multiple medicine cooperation has the characteristics that ingredient is more, effect link is more, can be played a role by too many levels, has synergistic treatment Effect improves curative effect, it is thus possible to effectively treat bite by mosquitos, slightly sprain, cuts scald, foot pain and infectious diseases The symptoms such as caused abscess；
(2) preparation method of green grass ointment of the present invention, wherein rose honey wine passes through unique work using rose, honey as raw material Skill makes rose honey wine, remains a variety of nutriments such as rose and honey, and use exclusive yeast, will be in white spirit process Distillation technique and the ageing phase be introduced into honey wine product, make hydromel that there is unique rose scent and shelf-life to obtain Extend, and then the shelf-life of green herbal medicine cream can be made to be extended, greatly improves the service life of green grass ointment.
Specific embodiment
The following examples can make professional and technical personnel that the present invention be more fully understood, but therefore not send out this It is bright to be limited among the embodiment described range.
Embodiment 1
The preparation method of the present embodiment green grass ointment, the preparation method include the following steps:
Step 1: solid material is crushed to particle size≤5 micron by comminuted solids raw material；Solid material includes the day of 2 money half The Radix Glycyrrhizae of Southern Star, 2 money half, the dried orange peel of 2 money half, the Cortex Magnoliae Officinalis of 2 money half, the rhizoma atractylodis of 5 money, the rheum officinale of 1 two 5 money, 1 two 5 money the root of Dahurain angelica, The radices trichosanthis of the Cortex Phellodendri of 1 two 5 money, the turmeric of 1 two 5 money and 2 two 1 money.
Step 2: preparing rose honey wine, specifically comprise the following steps:
The pretreatment of step a. rose: removing bennet, calyx for fresh rose, spare after cleaning, being broken；
Step b. prepares rose soak: mixing the rose of step 1 and water according to 1 ︰ 80 of feed liquid weight ratio, soaks at 50 DEG C 6h is steeped, rose soak is filtered to obtain；
The processing of step c. honey: weighing honey and rose soak puts into fermenter mixings, the addition relationship of the two for by Weight ratio meter, honey: rose soak=1:2；Then the Angel fruit wine yeast of liquid total weight 1 ‰ is added into fermentor Ferment at 24 DEG C 15d afterwards, obtains fermentation liquid；
Step d. distillation: taking the fermentation liquid in the step c of half volume, and heating distills out height honey white wine；
Step e. fermentation, ageing: the honey white wine that step d is steamed is put into remaining fermentation liquid, hair after continuing at 8 DEG C Ferment 120d, alcoholic strength 8%vol, while ageing 1 month or more；
Step f. sterilizing: it after the completion of ageing, is sterilized using 80 DEG C of pasteurizations；
Step g. filtering: it is finally filtered using the filter method of multistage diatomite, obtains the rose honey of clear Wine.
Step 3: the solid material crushed through step 1 is mixed with the rose honey wine for accounting for ointment gross mass 4% to be prepared Uniformly, ointment is obtained.
Embodiment 2
The preparation method of the present embodiment green grass ointment, the preparation method include the following steps:
Step 1: solid material is crushed to particle size≤5 micron by comminuted solids raw material；Solid material includes the day of 2 money half The Radix Glycyrrhizae of Southern Star, 2 money half, the dried orange peel of 2 money half, the Cortex Magnoliae Officinalis of 2 money half, the rhizoma atractylodis of 5 money, the rheum officinale of 1 two 5 money, 1 two 5 money the root of Dahurain angelica, The radices trichosanthis of the Cortex Phellodendri of 1 two 5 money, the turmeric of 1 two 5 money and 2 two 1 money.
Step 2: preparing rose honey wine, specifically comprise the following steps:
The pretreatment of step a. rose: removing bennet, calyx for fresh rose, spare after cleaning, being broken；
Step b. prepares rose soak: mixing the rose of step 1 and water according to 1 ︰ 80 of feed liquid weight ratio, soaks at 53 DEG C 5h is steeped, rose soak is filtered to obtain；
The processing of step c. honey: weighing honey and rose soak puts into fermenter mixings, the addition relationship of the two for by Weight ratio meter, honey: rose soak=1:2；Then the Angel fruit wine ferment of liquid total weight 1.5 ‰ is added into fermentor Imperial mother is fermented 13d at 25 DEG C, obtains fermentation liquid；
Step d. distillation: taking the fermentation liquid in the step c of half volume, and heating distills out height honey white wine；
Step e. fermentation, ageing: the honey white wine that step d is steamed is put into remaining fermentation liquid, after continuing at 10 DEG C Ferment 120d, alcoholic strength 10%vol, while ageing 1 month or more；
Step f. sterilizing: it after the completion of ageing, is sterilized using 80 DEG C of pasteurizations；
Step g. filtering: it is finally filtered using the filter method of multistage diatomite, obtains the rose honey of clear Wine.
Step 3: the solid material crushed through step 1 is mixed with the rose honey wine for accounting for ointment gross mass 4% to be prepared Uniformly, ointment is obtained.
Embodiment 3
The preparation method of the present embodiment green grass ointment, the preparation method include the following steps:
Step 1: solid material is crushed to particle size≤5 micron by comminuted solids raw material；Solid material includes the day of 2 money half The Radix Glycyrrhizae of Southern Star, 2 money half, the dried orange peel of 2 money half, the Cortex Magnoliae Officinalis of 2 money half, the rhizoma atractylodis of 5 money, the rheum officinale of 1 two 5 money, 1 two 5 money the root of Dahurain angelica, The radices trichosanthis of the Cortex Phellodendri of 1 two 5 money, the turmeric of 1 two 5 money and 2 two 1 money.
Step 2: preparing rose honey wine, specifically comprise the following steps:
The pretreatment of step a. rose: removing bennet, calyx for fresh rose, spare after cleaning, being broken；
Step b. prepares rose soak: mixing the rose of step 1 and water according to 1 ︰ 80 of feed liquid weight ratio, soaks at 55 DEG C 4.5h is steeped, rose soak is filtered to obtain；
The processing of step c. honey: weighing honey and rose soak puts into fermenter mixings, the addition relationship of the two for by Weight ratio meter, honey: rose soak=1:2；Then the Angel fruit wine yeast of liquid total weight 2 ‰ is added into fermentor Ferment at 26 DEG C 10d afterwards, obtains fermentation liquid；
Step d. distillation: taking the fermentation liquid in the step c of half volume, and heating distills out height honey white wine；
Step e. fermentation, ageing: the honey white wine that step d is steamed is put into remaining fermentation liquid, hair after continuing at 8 DEG C Ferment 120d, alcoholic strength 11%vol, while ageing 1 month or more；
Step f. sterilizing: it after the completion of ageing, is sterilized using 80 DEG C of pasteurizations；
Step g. filtering: it is finally filtered using the filter method of multistage diatomite, obtains the rose honey of clear Wine.
Step 3: the solid material crushed through step 1 is mixed with the rose honey wine for accounting for ointment gross mass 4% to be prepared Uniformly, ointment is obtained.
Clinical human's test is carried out with the ointment that ointment preparation method described in the 1st embodiment is prepared, in patent CN Under 106728246 A collating conditions, investigates it and sprained to bite by mosquitos, slightly, cut scald, foot pain, infectious diseases and draw The clinical efficacy and acceptance level of 80 patients's (there are no restrictions on age or sex) such as the abscess risen, as a result see the table below:
Patient class Total number of cases (people) 3 days or more in advance healing number of cases (people) 1-2 days in advance healing number of cases (people) Without number of cases (people) in advance Taste receives number of cases (people)
Bite by mosquitos 15 8 6 1 13
It is slight to sprain 16 9 7 0 15
Cut scald 15 7 6 2 14
Foot pain 9 6 2 1 7
Sore swell and ache curative 14 9 4 1 11
Erysipelas streamer 11 6 4 1 9
As can be seen from the above table, green grass ointment prepared by the present invention can effectively accelerate bite by mosquitos, slightly sprain, cut scald, The treatment of foot pain patient, simultaneously, moreover it is possible to effectively abscess caused by treatment infectious diseases, in addition, 85% or more patient's energy Enough tastes for receiving green grass ointment of the present invention.

Claims (2)

1. a kind of preparation method of green grass ointment, it is characterised in that: the preparation method includes the following steps:
Step 1: solid material is crushed to particle size≤5 micron by comminuted solids raw material；The solid material includes accounting for wait make Rhizoma arisaematis, 2.5% Radix Glycyrrhizae, 2.5% dried orange peel, 2.5% Cortex Magnoliae Officinalis, 5% rhizoma atractylodis, 15% of standby ointment gross mass 2.5% Rheum officinale, 15% root of Dahurain angelica, 15% Cortex Phellodendri, 15% turmeric and 21% radices trichosanthis；
Step 2: the solid material through crushing being uniformly mixed with the rose honey wine for accounting for ointment gross mass 4% to be prepared, is obtained Ointment.
2. the preparation method of green grass ointment according to claim 1, it is characterised in that: the rose honey in the step 2 Wine is through the following steps that be prepared:
The pretreatment of step a. rose: removing bennet, calyx for fresh rose, spare after cleaning, being broken；
Step b. prepares rose soak: step a spare rose is soaked in water, filtering, obtains filtrate, and as rose is soaked Steep liquid；The addition relationship of the two is rose: water=1:80 by weight；
The processing of step c. honey: weighing honey and rose soak puts into fermenter mixings, the addition relationship of the two for by Weight ratio meter, honey: rose soak=1:2；Then the saccharomyces cerevisiae of liquid total weight 1~2 ‰ is added into fermentor Ferment at 24~26 DEG C 10~15d afterwards, obtains fermentation liquid；
Step d. distillation: taking the fermentation liquid in the step c of half volume, and heating distills out height honey white wine；
Step e. fermentation, ageing: the honey white wine that step d is steamed is put into remaining fermentation liquid, is continued at 8~12 DEG C Post-fermentation to alcoholic strength reaches 8%vol or more, while ageing 1 month or more；
Step f. sterilizing: it after the completion of ageing, is sterilized using 80 DEG C of pasteurizations；
Step g. filtering: it is finally filtered using the filter method of multistage diatomite, obtains the rose honey of clear Wine.
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CN101850092A (en) * 2010-06-11 2010-10-06 卢振全 Medicament for treating trauma and preparation method thereof
CN105617270A (en) * 2016-02-18 2016-06-01 成都市飞龙水处理技术研究所青白江第一分所 Medicine for treating furuncle gall caused by heat and toxin stasis of skin and preparation method thereof
CN106434118A (en) * 2016-10-08 2017-02-22 北京同仁堂股份有限公司同仁堂药酒厂 Nutritious honey wine and preparation method thereof

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CN101850092A (en) * 2010-06-11 2010-10-06 卢振全 Medicament for treating trauma and preparation method thereof
CN105617270A (en) * 2016-02-18 2016-06-01 成都市飞龙水处理技术研究所青白江第一分所 Medicine for treating furuncle gall caused by heat and toxin stasis of skin and preparation method thereof
CN106434118A (en) * 2016-10-08 2017-02-22 北京同仁堂股份有限公司同仁堂药酒厂 Nutritious honey wine and preparation method thereof

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