CN110522883A - One kind controlling tinea pedis selenium-rich Chinese medicine composition and preparation method thereof - Google Patents
One kind controlling tinea pedis selenium-rich Chinese medicine composition and preparation method thereof Download PDFInfo
- Publication number
- CN110522883A CN110522883A CN201910738181.0A CN201910738181A CN110522883A CN 110522883 A CN110522883 A CN 110522883A CN 201910738181 A CN201910738181 A CN 201910738181A CN 110522883 A CN110522883 A CN 110522883A
- Authority
- CN
- China
- Prior art keywords
- parts
- selenium
- chinese medicine
- composition
- tinea pedis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/532—Agastache, e.g. giant hyssop
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Method of the present invention is related to health care product preparation technical field, especially one kind and controls tinea pedis selenium-rich Chinese medicine composition and preparation method thereof.Composition of the invention is mainly made of the raw material of following parts by weight: 20-30 parts of wrinkled giant hyssop, 10-18 parts of rhizoma polygonati, 5-8 parts of curcuma zedoary, 8-15 parts of ching-chieh, 1-2 parts of malt selenium and 3-8 parts of relaxing tendons and activating collaterals composition, the relaxing tendons and activating collaterals composition is combined by canarium pimela extract and small bolete.One kind of method of the present invention controls tinea pedis selenium-rich Chinese medicine composition and preparation method thereof, relaxing tendons and activating collaterals composition is to foot relaxing tendons and activating collaterals, promote absorption of its foot to other components drug, rhizoma polygonati plays good inhibition antifungal effect, curcuma zedoary and ching-chieh know good inducing diaphoresis anti-inflammatory effects, and wrinkled giant hyssop plays the role of deodorization and sterilization, and malt selenium and other components act synergistically, prevent tinea pedis repeatedly while antioxidation is played for pedal skin, further speed up the recovery of athlete's foot.
Description
Technical field
Method of the present invention is related to health care product preparation technical field, especially one kind and controls tinea pedis selenium-rich Chinese medicine composition and its system
Preparation Method.
Background technique
Tinea pedis is the foot dermatosis as caused by pathogenic fungus, has infectiousness.Tinea pedis is popular in the whole world, In
Subtropical and tropical zones are more universal.In China, the disease incidence of tinea pedis is also quite high.Without sebum between the vola and toe of people
Gland, to lack the fatty acid for inhibiting skin filamentous fungi, physiological defense function is poor, and the sweat gland of skin at these positions is very
It is abundant, it perspires relatively more, air circulation is poor in addition, part damp warm, is conducive to the growth of filamentous fungi.In addition, vola
Area skin cuticula is thicker, and the keratin in cuticula is the abundant nutrition substance of fungi, is conducive to the growth of fungi.
Foot is steeped using Chinese medicine, has to foot and receives sweat deodorization, the effect of bactericidal antiphlogistic.Pass through plantar reflecting region and channels and collaterals
It is passed to interior internal organs, is promoted blood circulation, organism balance is adjusted, helps body toxin expelling, can be relieved weakness, keep foot dynamic,
Foot cutin can also be softened, play health body-building, pleasant mental and body, stress of releiving.It is existing to control tinea pedis Traditional Chinese medicine for steeping foot material
The most health-care effect of composition is unobvious, and antibacterial and anti-inflammatory effects are bad.
Invention method content
The one kind that is designed to provide of method of the present invention controls tinea pedis selenium-rich Chinese medicine composition and preparation method thereof, overcomes aforementioned
The prior art controls the deficiency that the most health-care effect of tinea pedis Traditional Chinese medicine for steeping foot material composition is unobvious and antibacterial and anti-inflammatory effects are bad.
Method of the present invention solves its technical problem and is adopted the technical scheme that:
One kind controlling tinea pedis selenium-rich Chinese medicine composition, is mainly made of the raw material of following parts by weight: 20-30 parts of wrinkled giant hyssop,
10-18 parts of rhizoma polygonati, 5-8 parts of curcuma zedoary, 8-15 parts of ching-chieh, 1-2 parts of malt selenium and 3-8 parts of relaxing tendons and activating collaterals composition, the relaxing muscles and tendons
Active composition is by canarium pimela extract and small bolete according to (4-7): the proportion of (1-3) is combined.
Preferably, one kind controlling tinea pedis selenium-rich Chinese medicine composition: it is mainly made of the raw material of following parts by weight: wrinkled giant hyssop
25 parts, 14 parts of rhizoma polygonati, 6 parts of curcuma zedoary, 12 parts of ching-chieh, 2 parts of malt selenium and 6 parts of relaxing tendons and activating collaterals composition, the relaxing tendons and activating collaterals group
Object is closed to be combined with small bolete according to the proportion of 5:2 by canarium pimela extract.
Preferably, the extracting method of the canarium pimela extract includes the following steps:
(1) first by black canarytree root warm water wash clean, then with the immersion of 10% sodium chloride solution 3-5 minutes of 50-60 DEG C, then
It pulls out after draining away the water, is put into 60-70 DEG C of drying box, dry 30-40 minutes, be finally cooled to room temperature, be ground into 80-100
Purpose particle；
It (2) will be saccharomycete: lactic acid bacteria: acetic acid bacteria=(1-5): (3-8): the mixed bacteria that (9-12) is formed by weight ratio
Stoste accesses the black canarytree root particle in step (1), and ferments 2-3 days at normal temperature, wherein mixed bacteria stoste accounts for black canarytree root
The weight ratio of grain is 3-5%；
(3) black canarytree root after fermentation process is subjected to drying and processing, first in 80-90 DEG C of baking oven, dried 30-40 minutes,
Adjusting drying temperature again is 50-60 DEG C, is dried 50-60 minutes；
(4) it is to be extracted twice under 80-100kHz, room temperature in supersonic frequency by the black canarytree root in step (3), adds 4- for the first time
The distilled water of 6 times of weight extracts 30-60 minutes, and for the second time plus the distilled water of 4-6 times of weight, extraction 20-30 minutes are filtered, and closes
And filtrate, filtrate is placed on the centrifuge of 2000-3000r/min and is centrifuged 20-40 minutes, filtered again, is concentrated, it is dry, it obtains
To canarium pimela extract powder.
A kind of preparation method for controlling tinea pedis selenium-rich Chinese medicine composition, including following preparation step: by wrinkled giant hyssop part, rhizoma polygonati
Part, curcuma zedoary part, ching-chieh are cleaned, and using colloid mill soybean dietary fiber, obtain Chinese medicine slurry；Malt is added into Chinese medicine slurry
Selenium and relaxing tendons and activating collaterals composition stir 30-60min under 200-400r/min；Material after stirring is freezed using sonic vacuum
Drying means drying, less than 3%, obtains the freeze-dried powder for loading active ingredient to moisture content；The jelly of active ingredient will be loaded
Dry powder crushes again, obtains herb powder, and pack is sealed after weighing.
Preferably, the sonic vacuum is freeze-dried condition are as follows: and it is under ultrasonication that mixed material depth is cooling,
Make it in solid granulates, supersonic frequency 30-40kHz, ultrasonic power 40-100W, depth cooling temperature is -50--45 DEG C,
Cooling time is 2-3h；Stop refrigeration, starts vacuum plant to pressure 0.02-0.06Mpa, the program under vacuum and ultrasonication
35 DEG C, supersonic frequency 30-40kHz, ultrasonic power 40-100W are warming up to, freeze-dried powder is obtained.
The beneficial effect of method of the present invention is: compared with prior art, one kind of method of the present invention controls tinea pedis selenium-rich Chinese medicine group
Object and preparation method thereof is closed, relaxing tendons and activating collaterals composition promotes absorption of its foot to other components drug to foot relaxing tendons and activating collaterals,
Rhizoma polygonati plays good inhibition antifungal effect, and curcuma zedoary and ching-chieh know good inducing diaphoresis anti-inflammatory effects, and wrinkled giant hyssop plays sterilization and removes
Smelly effect, malt selenium and other components act synergistically, prevent tinea pedis repeatedly while antioxidation is played for pedal skin,
Further speed up the recovery of athlete's foot.
Specific embodiment
Embodiment 1
One kind controlling tinea pedis selenium-rich Chinese medicine composition, is mainly made of the raw material of following parts by weight: 25 parts of wrinkled giant hyssop, rhizoma polygonati
14 parts, 6 parts of curcuma zedoary, 12 parts of ching-chieh, 2 parts of malt selenium and 6 parts of relaxing tendons and activating collaterals composition, the relaxing tendons and activating collaterals composition is by canarium pimela
Extract is combined with small bolete according to the proportion of 5:2.
In the present embodiment, the extracting method of the canarium pimela extract includes the following steps:
(1) it first by black canarytree root warm water wash clean, then with the immersion of 10% sodium chloride solution 4 minutes of 55 DEG C, then pulls out
It after draining away the water, is put into 65 DEG C of drying box, dries 35 minutes, be finally cooled to room temperature, be ground into the particle of 90 mesh；
(2) will be saccharomycete: lactic acid bacteria by weight ratio: the mixed bacteria stoste that acetic acid bacteria=3:5:11 is formed accesses step
(1) the black canarytree root particle in, and ferment 2 days at normal temperature, wherein the weight ratio that mixed bacteria stoste accounts for black canarytree root particle is
4%；
(3) black canarytree root after fermentation process is subjected to drying and processing, first in 85 DEG C of baking oven, dried 35 minutes, then adjust
Drying temperature is 55 DEG C, is dried 55 minutes；
(4) it is to be extracted twice under 90kHz, room temperature in supersonic frequency by the black canarytree root in step (3), adds 5 times of weights for the first time
The distilled water of amount extracts 50 minutes, and for the second time plus the distilled water of 5 times of weight, extraction 25 minutes are filtered, merging filtrate, by filtrate
It is placed on the centrifuge of 2500r/min and is centrifuged 30 minutes, filter again, be concentrated, it is dry, obtain canarium pimela extract powder.
A kind of preparation method for controlling tinea pedis selenium-rich Chinese medicine composition, including following preparation step: by wrinkled giant hyssop part, rhizoma polygonati
Part, curcuma zedoary part, ching-chieh are cleaned, and using colloid mill soybean dietary fiber, obtain Chinese medicine slurry；Malt is added into Chinese medicine slurry
Selenium and relaxing tendons and activating collaterals composition stir 45min under 300r/min；Material after stirring is used into sonic vacuum freeze-drying method
Drying, less than 3%, obtains the freeze-dried powder for loading active ingredient to moisture content；The freeze-dried powder of active ingredient will be loaded again
It crushes, obtains herb powder, pack is sealed after weighing.
In the present embodiment, the sonic vacuum is freeze-dried condition are as follows: by mixed material depth under ultrasonication
It is cooling, make it in solid granulates, supersonic frequency 35kHz, ultrasonic power 75W, depth cooling temperature is -48 DEG C, when cooling
Between be 2.5h；Stop refrigeration, start vacuum plant to pressure 0.04Mpa, under vacuum and ultrasonication temperature programming to 35 DEG C,
Supersonic frequency is 35kHz, ultrasonic power 75W, obtains freeze-dried powder.
Embodiment 2
One kind controlling tinea pedis selenium-rich Chinese medicine composition, is mainly made of the raw material of following parts by weight: 20 parts of wrinkled giant hyssop, rhizoma polygonati
10 parts, 5 parts of curcuma zedoary, 8 parts of ching-chieh, 1 part of malt selenium and 3 parts of relaxing tendons and activating collaterals composition, the relaxing tendons and activating collaterals composition is by canarium pimela
Extract is combined with small bolete according to the proportion of 4:1.
In the present embodiment, the extracting method of the canarium pimela extract includes the following steps:
(1) it first by black canarytree root warm water wash clean, then with the immersion of 10% sodium chloride solution 3 minutes of 50 DEG C, then pulls out
It after draining away the water, is put into 60 DEG C of drying box, dries 30 minutes, be finally cooled to room temperature, be ground into the particle of 80 mesh；
(2) will be saccharomycete: lactic acid bacteria by weight ratio: the mixed bacteria stoste that acetic acid bacteria=1:3:9 is formed accesses step
(1) the black canarytree root particle in, and ferment 2 days at normal temperature, wherein the weight ratio that mixed bacteria stoste accounts for black canarytree root particle is
3%；
(3) black canarytree root after fermentation process is subjected to drying and processing, first in 80 DEG C of baking oven, dried 30 minutes, then adjust
Drying temperature is 50 DEG C, is dried 50 minutes；
(4) it is to be extracted twice under 80kHz, room temperature in supersonic frequency by the black canarytree root in step (3), adds 4 times of weights for the first time
The distilled water of amount extracts 30 minutes, and for the second time plus the distilled water of 4 times of weight, extraction 20 minutes are filtered, merging filtrate, by filtrate
It is placed on the centrifuge of 2000r/min and is centrifuged 20 minutes, filter again, be concentrated, it is dry, obtain canarium pimela extract powder.
A kind of preparation method for controlling tinea pedis selenium-rich Chinese medicine composition, including following preparation step: by wrinkled giant hyssop part, rhizoma polygonati
Part, curcuma zedoary part, ching-chieh are cleaned, and using colloid mill soybean dietary fiber, obtain Chinese medicine slurry；Malt is added into Chinese medicine slurry
Selenium and relaxing tendons and activating collaterals composition stir 30min under 200r/min；Material after stirring is used into sonic vacuum freeze-drying method
Drying, less than 3%, obtains the freeze-dried powder for loading active ingredient to moisture content；The freeze-dried powder of active ingredient will be loaded again
It crushes, obtains herb powder, pack is sealed after weighing.
Preferably, the sonic vacuum is freeze-dried condition are as follows: and it is under ultrasonication that mixed material depth is cooling,
Make it in solid granulates, supersonic frequency 30kHz, ultrasonic power 40W, depth cooling temperature are -50 DEG C, and cooling time is
2h；Stop refrigeration, start vacuum plant to pressure 0.02Mpa, temperature programming is to 35 DEG C under vacuum and ultrasonication, supersonic frequency
Rate is 30kHz, ultrasonic power 40W, obtains freeze-dried powder.
Embodiment 3
One kind controlling tinea pedis selenium-rich Chinese medicine composition, is mainly made of the raw material of following parts by weight: 30 parts of wrinkled giant hyssop, rhizoma polygonati
18 parts, 8 parts of curcuma zedoary, 15 parts of ching-chieh, 2 parts of malt selenium and 8 parts of relaxing tendons and activating collaterals composition, the relaxing tendons and activating collaterals composition is by canarium pimela
Extract is combined with small bolete according to the proportion of 7:3.
In the present embodiment, the extracting method of the canarium pimela extract includes the following steps:
(1) it first by black canarytree root warm water wash clean, then with the immersion of 10% sodium chloride solution 5 minutes of 60 DEG C, then pulls out
It after draining away the water, is put into 70 DEG C of drying box, dries 40 minutes, be finally cooled to room temperature, be ground into the particle of 100 mesh；
(2) will be saccharomycete: lactic acid bacteria by weight ratio: the mixed bacteria stoste that acetic acid bacteria=5:8:12 is formed accesses step
(1) the black canarytree root particle in, and ferment 3 days at normal temperature, wherein the weight ratio that mixed bacteria stoste accounts for black canarytree root particle is
5%；
(3) black canarytree root after fermentation process is subjected to drying and processing, first in 90 DEG C of baking oven, dried 40 minutes, then adjust
Drying temperature is 60 DEG C, is dried 60 minutes；
(4) it is to be extracted twice under 100kHz, room temperature in supersonic frequency by the black canarytree root in step (3), adds 6 times of weights for the first time
The distilled water of amount extracts 60 minutes, and for the second time plus the distilled water of 6 times of weight, extraction 30 minutes are filtered, merging filtrate, by filtrate
It is placed on the centrifuge of 3000r/min and is centrifuged 40 minutes, filter again, be concentrated, it is dry, obtain canarium pimela extract powder.
A kind of preparation method for controlling tinea pedis selenium-rich Chinese medicine composition, including following preparation step: by wrinkled giant hyssop part, rhizoma polygonati
Part, curcuma zedoary part, ching-chieh are cleaned, and using colloid mill soybean dietary fiber, obtain Chinese medicine slurry；Malt is added into Chinese medicine slurry
Selenium and relaxing tendons and activating collaterals composition stir 60min under 400r/min；Material after stirring is used into sonic vacuum freeze-drying method
Drying, less than 3%, obtains the freeze-dried powder for loading active ingredient to moisture content；The freeze-dried powder of active ingredient will be loaded again
It crushes, obtains herb powder, pack is sealed after weighing.
In the present embodiment, the sonic vacuum is freeze-dried condition are as follows: by mixed material depth under ultrasonication
It is cooling, make it in solid granulates, supersonic frequency 40kHz, ultrasonic power 100W, depth cooling temperature is -45 DEG C, when cooling
Between be 3h；Stop refrigeration, starts vacuum plant to pressure 0.06Mpa, temperature programming surpasses to 35 DEG C under vacuum and ultrasonication
Acoustic frequency is 40kHz, ultrasonic power 100W, obtains freeze-dried powder.
Comparative example 1
A kind of one kind for controlling tinea pedis selenium-rich Chinese medicine composition and embodiment 1 of comparative example 1 controls tinea pedis selenium-rich Chinese medicine group
It is essentially identical to close object, difference is: relaxing tendons and activating collaterals composition is by canarium pimela extract and small bolete according to 1:1 in comparative example 1
Proportion be combined.
A kind of preparation method for controlling tinea pedis selenium-rich Chinese medicine composition of comparative example 1 is same as Example 1.
Experimental example 1
Tinea pedis patient 40, male to female ratio 1:1 made a definite diagnosis through hospital are selected, is randomly divided into 4 groups, first group uses embodiment
Selenium-rich Chinese medicine composition made from 1, second group uses embodiment 3 using selenium-rich Chinese medicine composition made from embodiment 2, third group
Selenium-rich Chinese medicine composition obtained, the 4th group uses selenium-rich Chinese medicine composition made from comparative example 1, and every night is to 30-40 DEG C
3L sleep interior addition 20g selenium-rich Chinese medicine composition to steep foot, the bubble foot time is 15min, every 10 days as a treatment course, 3 treatments
It is as shown in table 1 that Rehabilitation situation is counted after journey:
Table 1
As can be seen from Table 1, the present invention has good effect to treatment tinea pedis.
Above-mentioned specific embodiment is only the specific case of method of the present invention, and the scope of patent protection of method of the present invention includes but not
It is limited to the product form and style of above-mentioned specific embodiment, it is any to meet method claims of the present invention and any affiliated technology
The appropriate changes or modifications that the those of ordinary skill in field does it, should all fall into the scope of patent protection of method of the present invention.
Claims (5)
1. one kind controls tinea pedis selenium-rich Chinese medicine composition, it is characterised in that: be mainly made of the raw material of following parts by weight: wrinkled giant hyssop
20-30 parts, 10-18 parts of rhizoma polygonati, 5-8 parts of curcuma zedoary, 8-15 parts of ching-chieh, 1-2 parts of malt selenium and 3-8 parts of relaxing tendons and activating collaterals composition,
The relaxing tendons and activating collaterals composition is by canarium pimela extract and small bolete according to (4-7): the proportion of (1-3) is combined.
2. one kind according to claim 1 controls tinea pedis selenium-rich Chinese medicine composition, it is characterised in that: mainly by following weight
The raw material of number forms: 25 parts of wrinkled giant hyssop, 14 parts of rhizoma polygonati, 6 parts of curcuma zedoary, 12 parts of ching-chieh, 2 parts of malt selenium and relaxing tendons and activating collaterals composition
6 parts, the relaxing tendons and activating collaterals composition is combined with small bolete according to the proportion of 5:2 by canarium pimela extract.
3. one kind according to claim 1 controls tinea pedis selenium-rich Chinese medicine composition, it is characterised in that: the canarium pimela extract
Extracting method include the following steps:
(1) it first by black canarytree root warm water wash clean, then with the immersion of 10% sodium chloride solution 3-5 minutes of 50-60 DEG C, then pulls out
It after draining away the water, is put into 60-70 DEG C of drying box, dries 30-40 minutes, be finally cooled to room temperature, be ground into 80-100 purpose
Particle；
It (2) will be saccharomycete: lactic acid bacteria: acetic acid bacteria=(1-5): (3-8): the mixed bacteria stoste that (9-12) is formed by weight ratio
The black canarytree root particle in step (1) is accessed, and is fermented 2-3 days at normal temperature, wherein mixed bacteria stoste accounts for black canarytree root particle
Weight ratio is 3-5%；
(3) black canarytree root after fermentation process is subjected to drying and processing, first in 80-90 DEG C of baking oven, dried 30-40 minutes, then adjust
Saving drying temperature is 50-60 DEG C, is dried 50-60 minutes；
(4) it is to be extracted twice under 80-100kHz, room temperature in supersonic frequency by the black canarytree root in step (3), adds 4-6 times for the first time
The distilled water of weight extracts 30-60 minutes, and for the second time plus the distilled water of 4-6 times of weight, extraction 20-30 minutes are filtered, and merges
Filtrate is placed on the centrifuge of 2000-3000r/min and is centrifuged 20-40 minutes, filters again by filtrate, is concentrated, dry, obtains
Canarium pimela extract powder.
4. a kind of preparation method for controlling tinea pedis selenium-rich Chinese medicine composition according to claim 1, it is characterised in that: including
Following preparation step: wrinkled giant hyssop part, rhizoma polygonati part, curcuma zedoary part, ching-chieh are cleaned, using colloid mill soybean dietary fiber, in acquisition
Medicinal material slurry；Malt selenium and relaxing tendons and activating collaterals composition are added into Chinese medicine slurry, stir 30-60min under 200-400r/min；It will stir
Material after mixing uses the drying of sonic vacuum freeze-drying method, less than 3%, to obtain to moisture content and load active ingredient
Freeze-dried powder；The freeze-dried powder for loading active ingredient is crushed again, obtains herb powder, pack is sealed after weighing.
5. a kind of preparation method for controlling tinea pedis selenium-rich Chinese medicine composition according to claim 4, it is characterised in that: described
Sonic vacuum is freeze-dried condition are as follows: and it is under ultrasonication that mixed material depth is cooling, make it in solid granulates, ultrasound
Frequency is 30-40kHz, ultrasonic power 40-100W, and depth cooling temperature is -50--45 DEG C, cooling time 2-3h；Stop
Refrigeration, starts vacuum plant to pressure 0.02-0.06Mpa, and temperature programming is to 35 DEG C under vacuum and ultrasonication, supersonic frequency
For 30-40kHz, ultrasonic power 40-100W, freeze-dried powder is obtained.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910738181.0A CN110522883A (en) | 2019-08-12 | 2019-08-12 | One kind controlling tinea pedis selenium-rich Chinese medicine composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910738181.0A CN110522883A (en) | 2019-08-12 | 2019-08-12 | One kind controlling tinea pedis selenium-rich Chinese medicine composition and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110522883A true CN110522883A (en) | 2019-12-03 |
Family
ID=68662959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910738181.0A Pending CN110522883A (en) | 2019-08-12 | 2019-08-12 | One kind controlling tinea pedis selenium-rich Chinese medicine composition and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110522883A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111821498A (en) * | 2020-09-04 | 2020-10-27 | 侯常刚 | Graphene bacteriostatic, bactericidal and deodorant Chinese herbal medicine pad combined layer |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104739777A (en) * | 2013-12-25 | 2015-07-01 | 汤广武 | Preparation method of single traditional Chinese medicinal powder |
| CN105558193A (en) * | 2015-12-22 | 2016-05-11 | 桂林双象生物科技有限公司 | Production method of composite tea made of folium ilicis hainanensis extract and eucommia ulmoides extract |
-
2019
- 2019-08-12 CN CN201910738181.0A patent/CN110522883A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104739777A (en) * | 2013-12-25 | 2015-07-01 | 汤广武 | Preparation method of single traditional Chinese medicinal powder |
| CN105558193A (en) * | 2015-12-22 | 2016-05-11 | 桂林双象生物科技有限公司 | Production method of composite tea made of folium ilicis hainanensis extract and eucommia ulmoides extract |
Non-Patent Citations (2)
| Title |
|---|
| 刘洪兰等: "中药浴足治疗足癣", 《中国民间疗法》 * |
| 张坤泉等: "浅谈乌榄药用的研究进展", 《中国实用医药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111821498A (en) * | 2020-09-04 | 2020-10-27 | 侯常刚 | Graphene bacteriostatic, bactericidal and deodorant Chinese herbal medicine pad combined layer |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103719423A (en) | Lucid ganoderma tea and preparation method thereof | |
| CN104957305B (en) | A kind of Ficus hispida fruit compounds hypoglycemic sifting tea and preparation method thereof | |
| CN107518133A (en) | A kind of relieving alcoholism and protecting liver jasmine tea and preparation method thereof | |
| CN106860680A (en) | Golden flower ginseng pressed candies and preparation method thereof | |
| CN106360213A (en) | Rhizoma polygonati plant beverage and preparation method thereof | |
| CN106974174A (en) | A kind of fruits and vegetables compound rice flour and preparation method thereof | |
| CN106343343A (en) | Lithocarpus polystachyus (DC.) Rehd tartarian buckwheat composition for reducing three-high and application thereof | |
| CN105062829A (en) | Sorghum health wine and preparation method thereof | |
| CN102940219B (en) | Potato cake and making method thereof | |
| CN106035878A (en) | Medicine and food homology functional tea and preparing method thereof | |
| CN106360683A (en) | Dendrobium officinale and banana compound probiotic fermentation products and method thereof | |
| CN105995558A (en) | Nutritious healthcare green bean cakes and preparing method thereof | |
| CN105055897A (en) | Health tea tablet capable of preventing and treating diabetes and preparation method of health tea tablet | |
| CN110522883A (en) | One kind controlling tinea pedis selenium-rich Chinese medicine composition and preparation method thereof | |
| CN107596197A (en) | A kind of strongly fragrant tea of tonifying Qi solution and preparation method thereof | |
| CN102370018A (en) | Burdock lily tea | |
| CN102511876B (en) | Hawthorn red jujube thick syrup and production process thereof | |
| CN106605832A (en) | Fruit and vegetable rice noodles for keeping young and preparation method of fruit and vegetable rice noodles | |
| CN106689523A (en) | Health grinding tea and production technology thereof | |
| CN105838543A (en) | Passion fruit wine yeast cake and making method thereof | |
| CN106579109A (en) | Citrus powder composition capable of neutralizing effect of alcoholic drinks and protecting liver, and preparation method of citrus powder composition | |
| CN106417817A (en) | Tea bag with effects of helping sleep and soothing nerves and preparation method thereof | |
| KR20130065375A (en) | Bread for oriental medicine noodle | |
| CN106085879A (en) | One medical material is the comprehensive mycelium of culture medium culturing Ganoderma | |
| CN102113562A (en) | Fig black sesame hair growing and blackening fruit powder and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20191203 |