CN110507829A - 铁钨复合氧化物纳米晶团簇的制备方法及其应用 - Google Patents
铁钨复合氧化物纳米晶团簇的制备方法及其应用 Download PDFInfo
- Publication number
- CN110507829A CN110507829A CN201910702198.0A CN201910702198A CN110507829A CN 110507829 A CN110507829 A CN 110507829A CN 201910702198 A CN201910702198 A CN 201910702198A CN 110507829 A CN110507829 A CN 110507829A
- Authority
- CN
- China
- Prior art keywords
- oxide nano
- water
- composite oxide
- soluble
- particle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910001145 Ferrotungsten Inorganic materials 0.000 title claims abstract description 40
- 239000002131 composite material Substances 0.000 title claims abstract description 40
- 239000002159 nanocrystal Substances 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 71
- 239000008367 deionised water Substances 0.000 claims abstract description 52
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 52
- 238000006243 chemical reaction Methods 0.000 claims abstract description 46
- 239000002105 nanoparticle Substances 0.000 claims abstract description 33
- 239000002245 particle Substances 0.000 claims abstract description 29
- 229920002873 Polyethylenimine Polymers 0.000 claims abstract description 24
- QGLKJKCYBOYXKC-UHFFFAOYSA-N nonaoxidotritungsten Chemical compound O=[W]1(=O)O[W](=O)(=O)O[W](=O)(=O)O1 QGLKJKCYBOYXKC-UHFFFAOYSA-N 0.000 claims abstract description 23
- 229910001930 tungsten oxide Inorganic materials 0.000 claims abstract description 23
- 150000002505 iron Chemical class 0.000 claims abstract description 14
- 239000002904 solvent Substances 0.000 claims abstract description 11
- 239000004094 surface-active agent Substances 0.000 claims abstract description 10
- 239000003513 alkali Substances 0.000 claims abstract description 9
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 9
- 150000001450 anions Chemical class 0.000 claims abstract description 8
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 150000003657 tungsten Chemical class 0.000 claims abstract description 8
- 229920003169 water-soluble polymer Polymers 0.000 claims abstract description 8
- 239000005416 organic matter Substances 0.000 claims abstract description 7
- 238000000975 co-precipitation Methods 0.000 claims abstract description 3
- 239000000126 substance Substances 0.000 claims abstract description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 10
- 229920002125 Sokalan® Polymers 0.000 claims description 7
- 239000004584 polyacrylic acid Substances 0.000 claims description 7
- 239000001509 sodium citrate Substances 0.000 claims description 7
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical group O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 7
- 238000005406 washing Methods 0.000 claims description 7
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 6
- 239000001301 oxygen Substances 0.000 claims description 6
- 229910052760 oxygen Inorganic materials 0.000 claims description 6
- -1 iron ion Chemical class 0.000 claims description 5
- 229910052742 iron Inorganic materials 0.000 claims description 4
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 3
- 239000002872 contrast media Substances 0.000 claims description 3
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 2
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims description 2
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 claims description 2
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 2
- 230000002902 bimodal effect Effects 0.000 claims description 2
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims description 2
- 229960001484 edetic acid Drugs 0.000 claims description 2
- 229910001447 ferric ion Inorganic materials 0.000 claims description 2
- 229910001448 ferrous ion Inorganic materials 0.000 claims description 2
- 238000002955 isolation Methods 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 2
- HELHAJAZNSDZJO-OLXYHTOASA-L sodium L-tartrate Chemical compound [Na+].[Na+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O HELHAJAZNSDZJO-OLXYHTOASA-L 0.000 claims description 2
- 235000011083 sodium citrates Nutrition 0.000 claims description 2
- 239000001433 sodium tartrate Substances 0.000 claims description 2
- 229960002167 sodium tartrate Drugs 0.000 claims description 2
- 235000011004 sodium tartrates Nutrition 0.000 claims description 2
- 239000011975 tartaric acid Substances 0.000 claims description 2
- 235000002906 tartaric acid Nutrition 0.000 claims description 2
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims 1
- SYZKBMPNHSQNHG-UHFFFAOYSA-N [Na].CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.NCCN Chemical compound [Na].CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.NCCN SYZKBMPNHSQNHG-UHFFFAOYSA-N 0.000 claims 1
- 238000001338 self-assembly Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 10
- 238000000034 method Methods 0.000 abstract description 7
- 238000005979 thermal decomposition reaction Methods 0.000 abstract description 2
- 239000000243 solution Substances 0.000 description 72
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 30
- 238000003756 stirring Methods 0.000 description 25
- 239000000047 product Substances 0.000 description 11
- 239000006185 dispersion Substances 0.000 description 9
- 239000007788 liquid Substances 0.000 description 9
- 238000003384 imaging method Methods 0.000 description 8
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 6
- 239000000908 ammonium hydroxide Substances 0.000 description 6
- 229940044631 ferric chloride hexahydrate Drugs 0.000 description 6
- SZVJSHCCFOBDDC-UHFFFAOYSA-N ferrosoferric oxide Chemical compound O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 description 6
- WSSMOXHYUFMBLS-UHFFFAOYSA-L iron dichloride tetrahydrate Chemical group O.O.O.O.[Cl-].[Cl-].[Fe+2] WSSMOXHYUFMBLS-UHFFFAOYSA-L 0.000 description 6
- NQXWGWZJXJUMQB-UHFFFAOYSA-K iron trichloride hexahydrate Chemical group O.O.O.O.O.O.[Cl-].Cl[Fe+]Cl NQXWGWZJXJUMQB-UHFFFAOYSA-K 0.000 description 6
- 238000002595 magnetic resonance imaging Methods 0.000 description 6
- YOUIDGQAIILFBW-UHFFFAOYSA-J tetrachlorotungsten Chemical compound Cl[W](Cl)(Cl)Cl YOUIDGQAIILFBW-UHFFFAOYSA-J 0.000 description 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 5
- 238000009835 boiling Methods 0.000 description 5
- 230000008859 change Effects 0.000 description 5
- 229910001873 dinitrogen Inorganic materials 0.000 description 5
- 238000004090 dissolution Methods 0.000 description 5
- 238000010907 mechanical stirring Methods 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 239000012299 nitrogen atmosphere Substances 0.000 description 5
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 5
- 239000010937 tungsten Substances 0.000 description 5
- 229910052721 tungsten Inorganic materials 0.000 description 5
- 238000010792 warming Methods 0.000 description 5
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 238000002601 radiography Methods 0.000 description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 230000003321 amplification Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000006555 catalytic reaction Methods 0.000 description 2
- 238000002059 diagnostic imaging Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940056319 ferrosoferric oxide Drugs 0.000 description 2
- SURQXAFEQWPFPV-UHFFFAOYSA-L iron(2+) sulfate heptahydrate Chemical compound O.O.O.O.O.O.O.[Fe+2].[O-]S([O-])(=O)=O SURQXAFEQWPFPV-UHFFFAOYSA-L 0.000 description 2
- 239000011259 mixed solution Substances 0.000 description 2
- 239000002086 nanomaterial Substances 0.000 description 2
- 238000003199 nucleic acid amplification method Methods 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- SDDGNMXIOGQCCH-UHFFFAOYSA-N 3-fluoro-n,n-dimethylaniline Chemical group CN(C)C1=CC=CC(F)=C1 SDDGNMXIOGQCCH-UHFFFAOYSA-N 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- XAYGUHUYDMLJJV-UHFFFAOYSA-Z decaazanium;dioxido(dioxo)tungsten;hydron;trioxotungsten Chemical compound [H+].[H+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.[O-][W]([O-])(=O)=O.[O-][W]([O-])(=O)=O.[O-][W]([O-])(=O)=O.[O-][W]([O-])(=O)=O.[O-][W]([O-])(=O)=O.[O-][W]([O-])(=O)=O XAYGUHUYDMLJJV-UHFFFAOYSA-Z 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000009881 electrostatic interaction Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- BEGBSFPALGFMJI-UHFFFAOYSA-N ethene;sodium Chemical group [Na].C=C BEGBSFPALGFMJI-UHFFFAOYSA-N 0.000 description 1
- 239000011640 ferrous citrate Substances 0.000 description 1
- 235000019850 ferrous citrate Nutrition 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000011147 inorganic material Substances 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- APVZWAOKZPNDNR-UHFFFAOYSA-L iron(ii) citrate Chemical compound [Fe+2].OC(=O)CC(O)(C([O-])=O)CC([O-])=O APVZWAOKZPNDNR-UHFFFAOYSA-L 0.000 description 1
- 229910044991 metal oxide Inorganic materials 0.000 description 1
- 150000004706 metal oxides Chemical class 0.000 description 1
- 239000002114 nanocomposite Substances 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000010865 sewage Substances 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- XMVONEAAOPAGAO-UHFFFAOYSA-N sodium tungstate Chemical compound [Na+].[Na+].[O-][W]([O-])(=O)=O XMVONEAAOPAGAO-UHFFFAOYSA-N 0.000 description 1
- ITRNXVSDJBHYNJ-UHFFFAOYSA-N tungsten disulfide Chemical compound S=[W]=S ITRNXVSDJBHYNJ-UHFFFAOYSA-N 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
- 229910006297 γ-Fe2O3 Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1887—Agglomerates, clusters, i.e. more than one (super)(para)magnetic microparticle or nanoparticle are aggregated or entrapped in the same maxtrix
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y40/00—Manufacture or treatment of nanostructures
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G41/00—Compounds of tungsten
- C01G41/02—Oxides; Hydroxides
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G49/00—Compounds of iron
- C01G49/02—Oxides; Hydroxides
- C01G49/08—Ferroso-ferric oxide [Fe3O4]
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2004/00—Particle morphology
- C01P2004/01—Particle morphology depicted by an image
- C01P2004/04—Particle morphology depicted by an image obtained by TEM, STEM, STM or AFM
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- General Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Manufacturing & Machinery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compounds Of Iron (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910702198.0A CN110507829B (zh) | 2019-07-31 | 2019-07-31 | 铁钨复合氧化物纳米晶团簇的制备方法及其应用 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910702198.0A CN110507829B (zh) | 2019-07-31 | 2019-07-31 | 铁钨复合氧化物纳米晶团簇的制备方法及其应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110507829A true CN110507829A (zh) | 2019-11-29 |
| CN110507829B CN110507829B (zh) | 2021-08-31 |
Family
ID=68623811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910702198.0A Active CN110507829B (zh) | 2019-07-31 | 2019-07-31 | 铁钨复合氧化物纳米晶团簇的制备方法及其应用 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110507829B (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114053966A (zh) * | 2021-03-04 | 2022-02-18 | 中国科学院宁波材料技术与工程研究所 | 一种亲水性磁性纳米材料及其制备方法与应用 |
| CN114229898A (zh) * | 2021-12-09 | 2022-03-25 | 沈阳化工大学 | 一种用模板制备多面体三氧化钨方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103341183A (zh) * | 2013-06-13 | 2013-10-09 | 上海师范大学 | 纳米氧化钨wo2.9在ct造影剂材料中的应用 |
| CN107899023A (zh) * | 2017-12-28 | 2018-04-13 | 山西省肿瘤医院 | 一种纳米造影剂及其制备方法 |
-
2019
- 2019-07-31 CN CN201910702198.0A patent/CN110507829B/zh active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103341183A (zh) * | 2013-06-13 | 2013-10-09 | 上海师范大学 | 纳米氧化钨wo2.9在ct造影剂材料中的应用 |
| CN107899023A (zh) * | 2017-12-28 | 2018-04-13 | 山西省肿瘤医院 | 一种纳米造影剂及其制备方法 |
Non-Patent Citations (2)
| Title |
|---|
| ZHIYIN XIAO等: "Polypyrrole-encapsulated Iron Tungstate Nanocomposites: A Versatile Platform for Multimodal Tumor Imaging and Photothermal Therapy", 《NANOSCALE》 * |
| 吴可嘉: "Fe3O4-WOx-CQD多功能体系的构筑、表征及性能研究", 《万方数据平台》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114053966A (zh) * | 2021-03-04 | 2022-02-18 | 中国科学院宁波材料技术与工程研究所 | 一种亲水性磁性纳米材料及其制备方法与应用 |
| CN114229898A (zh) * | 2021-12-09 | 2022-03-25 | 沈阳化工大学 | 一种用模板制备多面体三氧化钨方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110507829B (zh) | 2021-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Olsson et al. | Controlled synthesis of near-stoichiometric cobalt ferrite nanoparticles | |
| Cai et al. | Large-scale, facile transfer of oleic acid-stabilized iron oxide nanoparticles to the aqueous phase for biological applications | |
| CN105288666B (zh) | 一种水溶性蛋白包覆的磁性纳米颗粒及其制备方法 | |
| CN102125699B (zh) | Fe3O4复合TiO2纳米粒子及其制备方法以及在磁共振成像造影剂中的应用 | |
| JP5765520B2 (ja) | 磁性粒子含有水分散体の製造方法 | |
| CN101417822B (zh) | 超顺磁介孔四氧化三铁纳米粒子的制备方法 | |
| CN100446134C (zh) | 氧化铁粒子悬浮液的制备方法 | |
| Puvvada et al. | Shape dependent peroxidase mimetic activity towards oxidation of pyrogallol by H 2 O 2 | |
| CN106913885B (zh) | 一种磁性纳米粒子及其制备方法和应用 | |
| CN105271433B (zh) | 一种锌掺杂的超顺磁四氧化三铁纳米颗粒的水热合成制备方法 | |
| CN110507829A (zh) | 铁钨复合氧化物纳米晶团簇的制备方法及其应用 | |
| CN101935070A (zh) | 丙烯酸类聚合物纳米水凝胶诱导原位合成超顺磁性四氧化三铁纳米粒子的方法 | |
| CN101279769B (zh) | 强磁性四氧化三铁纳米材料的制备方法 | |
| CN110665465A (zh) | 用于糖肽富集的磁性共价有机框架材料及其制备方法与应用 | |
| CN114042168B (zh) | 一种双金属硫化物纳米探针的制备及应用 | |
| CN106010500A (zh) | 一种具有核壳结构的磁性纳米发光材料及其制备方法 | |
| CN111228487B (zh) | 含石墨化荧光碳点且具有yolk-shell结构的磁性粒子及其制备方法和应用 | |
| CN110550666B (zh) | 一种单分散、超顺磁性四氧化三铁纳米花及其制备方法 | |
| CN108455682A (zh) | 一种水性Fe3O4纳米粉体的制备方法 | |
| CN107213474A (zh) | 一种铁基磁性纳米晶磁共振t1造影剂的制备方法及其应用 | |
| CN102430130B (zh) | 一种医药用改性葡聚糖包覆磁性纳米颗粒复合材料及其制备方法 | |
| CN103007302A (zh) | Gd2O3-TiO2复合纳米粒子及其制备方法和应用 | |
| Zheng et al. | Breast cancer diagnosed by MRI using mesoporous TiO2-coated (Fe3O4) nanoparticles | |
| CN115180654A (zh) | 高纯度硫化铁纳米酶的制备方法和应用 | |
| CN102910684A (zh) | 单分散四氧化三铁纳米颗粒的克规模合成方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20191129 Assignee: Yunnan Benyi Biotechnology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023530000011 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230403 Application publication date: 20191129 Assignee: Kunming Junxiang Pharmaceutical Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023530000013 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230403 Application publication date: 20191129 Assignee: Kunming Daren Medical Equipment Co.,Ltd. Assignor: Hubei University Contract record no.: X2023530000012 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230403 |
|
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20191129 Assignee: Hubei yapunodi Technology Development Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000144 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230606 Application publication date: 20191129 Assignee: Hubei Yunyihui Medical Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000143 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230606 |
|
| EE01 | Entry into force of recordation of patent licensing contract | ||
| EE01 | Entry into force of recordation of patent licensing contract | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20191129 Assignee: Hubei Yueming Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000151 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230608 Application publication date: 20191129 Assignee: BORUNCHENG (WUHAN) PHARMACEUTICAL CO.,LTD. Assignor: Hubei University Contract record no.: X2023420000155 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230608 Application publication date: 20191129 Assignee: Wuhan Dorman Health Technology Partnership (L.P.) Assignor: Hubei University Contract record no.: X2023420000149 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230607 Application publication date: 20191129 Assignee: Wuhan Zhencai Intelligent Manufacturing Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000150 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230608 Application publication date: 20191129 Assignee: Wuhan Hengtai Bainian Trading Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000157 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230609 Application publication date: 20191129 Assignee: Wuhan Yihui Medical Technology Service Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000158 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230609 Application publication date: 20191129 Assignee: Hubei Wanhai Saikang Life Science Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000154 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230608 Application publication date: 20191129 Assignee: Wuhan golden Jirui Medical Technology Development Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000152 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230608 Application publication date: 20191129 Assignee: Wuhan Zero Action Medical Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000148 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230607 Application publication date: 20191129 Assignee: Wuhan Weier Laibo Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000153 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230608 Application publication date: 20191129 Assignee: Wuhan Ruixin Zetai Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000156 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230608 |
|
| EE01 | Entry into force of recordation of patent licensing contract | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20191129 Assignee: Wuhan Kaikang Technology Development Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000164 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230612 Application publication date: 20191129 Assignee: Wuhan Lingyi Medical Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000160 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230612 Application publication date: 20191129 Assignee: Hubei Zeshunzhi Science and Trade Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000174 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230614 Application publication date: 20191129 Assignee: Wuhan Jingdong Medical Technology Partnership (L.P.) Assignor: Hubei University Contract record no.: X2023420000159 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230612 Application publication date: 20191129 Assignee: Wuhan Warmth Medical Services Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000178 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230615 Application publication date: 20191129 Assignee: Wuhan Zhencai Zhizao Medical Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000162 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230612 Application publication date: 20191129 Assignee: Hubei Zheshunkai Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000177 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230615 Application publication date: 20191129 Assignee: Hubei Shengrui Medical Equipment Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000163 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230612 Application publication date: 20191129 Assignee: Wuhan Dorman Health Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000161 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230612 Application publication date: 20191129 Assignee: WUHAN JUNAN YOULIAN MEDICAL TECHNOLOGY Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000165 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230612 |
|
| EE01 | Entry into force of recordation of patent licensing contract | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20191129 Assignee: Wuhan Shuidi 1872 Medical Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000180 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230616 Application publication date: 20191129 Assignee: Wuhan Youyimo Medical Technology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000179 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230616 Application publication date: 20191129 Assignee: Hanli Kechuang (Wuhan) Medical Service Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000182 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230616 Application publication date: 20191129 Assignee: Wuhan Yiran Biotechnology Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000181 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230616 Application publication date: 20191129 Assignee: Wuhan Youyimo Hankou Medical Management Co.,Ltd. Assignor: Hubei University Contract record no.: X2023420000184 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230616 |
|
| EE01 | Entry into force of recordation of patent licensing contract | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20191129 Assignee: Weimi Medical (Yunnan) Co.,Ltd. Assignor: Hubei University Contract record no.: X2023980040027 Denomination of invention: Preparation Method and Application of Iron Tungsten Composite Oxide Nanocrystalline Clusters Granted publication date: 20210831 License type: Common License Record date: 20230822 |