CN110507795A - For preventing the external medicine composition of the retention of urine and application after painless delivery - Google Patents
For preventing the external medicine composition of the retention of urine and application after painless delivery Download PDFInfo
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- CN110507795A CN110507795A CN201910779401.4A CN201910779401A CN110507795A CN 110507795 A CN110507795 A CN 110507795A CN 201910779401 A CN201910779401 A CN 201910779401A CN 110507795 A CN110507795 A CN 110507795A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract
For preventing the external medicine composition of the retention of urine and application after painless delivery.The object of the present invention is to provide a kind of for preventing the external medicine composition of the retention of urine after painless delivery, the Chinese medicine composition is consist of the following weight ratio drug substance: 100-300 parts of the shell of areca nut, rhizoma zingiberis 200-500 Fen , pivot stores 150-450 parts, 150-450 parts of honeysuckle, 100-300 parts of borneol.Usefulness of the present invention is: (1) pharmaceutical composition of the present invention has solid classical theory of traditional chinese medicine gynecology to support, reasonable mixture ratio of components；(2) clinical efficacy of the present invention is definite, has no toxic side effect, and use is safe, can prepare for preventing to apply in the external medicine composition of the retention of urine after painless delivery；(3) pharmaceutical composition flavour of a drug of the present invention are few, are easy to quality control, while low in cost.
Description
Technical field
The invention belongs to Chinese medicine composition, be related to it is a kind of for prevent after painless delivery the external medicine composition of the retention of urine and
Its medicinal usage.
Background technique
There is urination disorder after referring to parturient childbirth or is unable to automatic micturition completely in postpartum retention of urine, and puerpera occurs obviously not
Suitable symptom, while urinary system infection contamination incidence dramatically increases, and brings serious negative effect to puerpera's physiology and psychology.It is painless
Childbirth, which refers to, reduces the pain of puerpera in the progress of labor with drug or psychotherapy.With puerpera to the service requests of obstetrics not
Disconnected to improve, painless delivery just becomes increasingly popular.But postpartum retention of urine problem caused by painless delivery annoying always medical staff and
Puerpera.
Traditional Chinese medicine thinks, this disease is mostly by ferritic weakness, and labour feels frustrated or excessive blood loss when production, wasting of QI following consumption of blood, so that lung spleen
The deficiency of vital energy is unable to regulating fluid apssage, under defeated bladder, functioning of bladder is unfavorable and causes urinary obstruction；Or native endowment is insufficient, kidney qi is weak,
Multiple because damaging kidney qi when producing, the insufficiency of the kidney yang, the Yang-function insufficiency of kidneyzang, bladder loses that its is warm, disturbance in qi transformation therefore urinary obstruction；Or because of postpartum feelings
Will is unsuccessful, stagnation of liver qi, and mechanism of qi retardance, pure and impure disturbance in ascending and descending, functioning of bladder is unfavorable and causes urinary obstruction；Or because of bradytoia, bladder
It is pressurized too long, QI-blood circulation is unsmooth, and functioning of bladder is unfavorable and causes urinary obstruction.
Summary of the invention
The object of the present invention is to provide a kind of for preventing the external medicine composition of the retention of urine after painless delivery, the Chinese medicine
Composition is consist of the following weight ratio drug substance: 100-300 parts of the shell of areca nut, rhizoma zingiberis 200-500 Fen , pivot stores 150-450 parts,
150-450 parts of honeysuckle, 100-300 parts of borneol.The weight of the above component is calculated with crude drug.Every 1 part can be 1g, be also possible to
Kilogram or ton, if with gram as unit of, which can be made into 1000 doses of pharmaceutical preparation.Composition described above is to be used as to match by weight
Ratio, can be increased or reduced according to corresponding proportion in production, as large-scale production can by kilogram as unit of, or with ton be single
Position, small-scale production can also milligram be unit, weight can increase or reduce, but the raw medicinal herbs weight proportion between each composition
Constant rate.
It is a further object to provide the Chinese medicine composition in preparation for urinating pool after preventing painless delivery
The application in external drug stayed.The drug is made of composition and excipient, and the dosage form of drug is gelling agent.
Usefulness of the present invention is: (1) pharmaceutical composition of the present invention has solid classical theory of traditional chinese medicine gynecology to support, group
Distribution ratio is reasonable；(2) clinical efficacy of the present invention is definite, has no toxic side effect, and use is safe, can be in preparation for preventing painless delivery
It is applied in the external medicine composition of the retention of urine afterwards；(3) pharmaceutical composition flavour of a drug of the present invention are few, are easy to quality control, while at
This is cheap.
Specific embodiment
The present invention is further described by specific embodiment.
Embodiment 1
Pharmaceutical composition composition: shell of areca nut 100g, rhizoma zingiberis 200g , pivot store 150g, honeysuckle 150g, borneol 100g.
Preparation method:
(1) borneol is taken to soak in water 2 hours, the saturated oil saturated aqueous solution collected with steam distillation is put into another container
Storage, it is spare；
(2) shell of areca nut is taken, rhizoma zingiberis , pivot stores, and honeysuckle powder is broken into coarse powder, the above-mentioned dregs of a decoction are added, adds water to cook 2 times, 1 is small every time
When, decocting liquid in merging, filtration, filtrate is concentrated into the clear cream that relative concentration is 1.03-1.05 (50 DEG C), places 24 hours, be added
Traditional Chinese medicine gel is made in excipient (carbomer).
Embodiment 2
Pharmaceutical composition composition: shell of areca nut 150g, rhizoma zingiberis 275g , pivot store 225g, honeysuckle 225g, borneol 150g.
Preparation method:
(1) borneol is taken to soak in water 2 hours, the saturated oil saturated aqueous solution collected with steam distillation is put into another container
Storage, it is spare；
(2) shell of areca nut is taken, rhizoma zingiberis , pivot stores, and honeysuckle powder is broken into coarse powder, the above-mentioned dregs of a decoction are added, adds water to cook 2 times, 1 is small every time
When, decocting liquid in merging, filtration, filtrate is concentrated into the clear cream that relative concentration is 1.03-1.05 (50 DEG C), places 24 hours, be added
Traditional Chinese medicine gel is made in excipient (carbomer).
Embodiment 3
Pharmaceutical composition composition: shell of areca nut 200g, rhizoma zingiberis 350g , pivot store 300g, honeysuckle 300g, borneol 200g.
Preparation method:
(1) borneol is taken to soak in water 2 hours, the saturated oil saturated aqueous solution collected with steam distillation is put into another container
Storage, it is spare.
(2) shell of areca nut is taken, rhizoma zingiberis , pivot stores, and honeysuckle powder is broken into coarse powder, the above-mentioned dregs of a decoction are added, adds water to cook 2 times, 1 is small every time
When, decocting liquid in merging, filtration, filtrate is concentrated into the clear cream that relative concentration is 1.03-1.05 (50 DEG C), places 24 hours, be added
Traditional Chinese medicine gel is made in excipient (carbomer).
Embodiment 4
Pharmaceutical composition composition: shell of areca nut 250g, rhizoma zingiberis 425g , pivot store 375g, honeysuckle 375g, borneol 250g.
Preparation method:
(1) borneol is taken to soak in water 2 hours, the saturated oil saturated aqueous solution collected with steam distillation is put into another container
Storage, it is spare；
(2) shell of areca nut is taken, rhizoma zingiberis , pivot stores, and honeysuckle powder is broken into coarse powder, the above-mentioned dregs of a decoction are added, adds water to cook 2 times, 1 is small every time
When, decocting liquid in merging, filtration, filtrate is concentrated into the clear cream that relative concentration is 1.03-1.05 (50 DEG C), places 24 hours, be added
Traditional Chinese medicine gel is made in excipient (carbomer).
Embodiment 5
Pharmaceutical composition composition: shell of areca nut 300g, rhizoma zingiberis 500g , pivot store 450g, honeysuckle 450g, borneol 300g.
Preparation method:
(1) borneol is taken to soak in water 2 hours, the saturated oil saturated aqueous solution collected with steam distillation is put into another container
Storage, it is spare；
(2) shell of areca nut is taken, rhizoma zingiberis , pivot stores, and honeysuckle powder is broken into coarse powder, the above-mentioned dregs of a decoction are added, adds water to cook 2 times, 1 is small every time
When, decocting liquid in merging, filtration, filtrate is concentrated into the clear cream that relative concentration is 1.03-1.05 (50 DEG C), places 24 hours, be added
Traditional Chinese medicine gel is made in excipient (carbomer).
Embodiment 6
1. case is collected and grouping:
Select the puerpera of 176 Via vagina painless deliveries.It is included in standard: the age 20-40 years old, having received relevant knowledge a surname that gives a birth
Religion excludes severe complication and complication, is randomly divided into Chinese medicine external intervention group (n=86) and control group (n=90).Two groups of productions
Woman's age, nutrition, educational level, pregnant week, stages of labor, painless delivery drug dose and neonatal weight etc. comparing difference are without system
Meter learns meaning, is comparable.
2. treatment method:
Control group: antenatal receiving is given a birth relevant knowledge propaganda and education, presses postpartum routine care after parturient childbirth；Chinese medicine external intervention group produces
Woman's postpartum 1-2h uses this pharmaceutical composition (composition: shell of areca nut 20g, rhizoma zingiberis 35g , pivot store 30g, honeysuckle 30g, borneol 20g)
Gel is smeared, and 1 time per hour, continuous 6 times.
3. observation index and statistical method:
Observing time, the smooth degree of urination and the retention of urine that two groups of puerperas urinate in postpartum for the first time, a situation arises.
It urinates smooth degree: smooth: can voluntary micturition when having urine intention；It has some setbacks: having urine intention urination more difficult, need when urination
It holds one's breath firmly, the urine flow sound of rain pattering and not at line has urine retention sense；Dysuria: urine intention is unable to voluntary micturition.
Statistical analysis is carried out using 20.0 software package of SPSS, enumeration data uses chi-square criterion, and measurement data is examined using t
It tests, P < 0.05 is that difference is statistically significant.
4. result
(1) urination time for the first time: Chinese medicine external intervention group postpartum, urination time was better than control group for the first time, and two groups relatively have statistics
Meaning (P < 0.05) (table 1).
Table 1: urination time for the first time
| Group | 2-5h | 6-8h | >8h |
| Chinese medicine external intervention group (n=86) | 71 | 9 | 6 |
| Control group (n=90) | 32 | 41 | 17 |
* there is significant difference in P < 0.05 compared with Western medicine group.
(2) a situation arises for smooth degree of urinating and the retention of urine:
The smooth degree of Chinese medicine external intervention group puerpera urination, retention of urine situation compare better than control group, and two groups of comparing differences have system
Meter learns meaning (P < 0.05) (table 2).
Table 2: a situation arises for smooth degree of urinating and the retention of urine
* there is significant difference in P < 0.05 compared with Western medicine group.
Claims (3)
1. a kind of external medicine composition for preventing the retention of urine after painless delivery, which is characterized in that the Chinese medicine composition is by following
The bulk pharmaceutical chemicals of weight proportion form: 100-300 parts of the shell of areca nut, rhizoma zingiberis 200-500 Fen , pivot stores 150-450 parts, honeysuckle 150-
450 parts, 100-300 parts of borneol.
2. a kind of external medicine composition for preventing the retention of urine after painless delivery according to claim 1 is in preparation for pre-
Application after anti-painless delivery in the external drug of the retention of urine.
3. a kind of application for preventing the external medicine composition of the retention of urine after painless delivery according to claim 2, special
Sign is that the drug is made of composition and excipient, and the dosage form of drug is gelling agent.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910779401.4A CN110507795A (en) | 2019-08-22 | 2019-08-22 | For preventing the external medicine composition of the retention of urine and application after painless delivery |
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|---|---|---|---|
| CN201910779401.4A CN110507795A (en) | 2019-08-22 | 2019-08-22 | For preventing the external medicine composition of the retention of urine and application after painless delivery |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1360844A (en) * | 2000-12-26 | 2002-07-31 | 郭元国 | Compound recuperating tea and its production process |
| CN103431117A (en) * | 2013-09-03 | 2013-12-11 | 四川大学 | Preparation method for micro-nano citrullus vulgaris schrad herbal tea |
| CN105311124A (en) * | 2014-08-05 | 2016-02-10 | 陈盼盼 | Prescription for treating urinary tract infection |
-
2019
- 2019-08-22 CN CN201910779401.4A patent/CN110507795A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1360844A (en) * | 2000-12-26 | 2002-07-31 | 郭元国 | Compound recuperating tea and its production process |
| CN103431117A (en) * | 2013-09-03 | 2013-12-11 | 四川大学 | Preparation method for micro-nano citrullus vulgaris schrad herbal tea |
| CN105311124A (en) * | 2014-08-05 | 2016-02-10 | 陈盼盼 | Prescription for treating urinary tract infection |
Non-Patent Citations (1)
| Title |
|---|
| 刘玉宁、郭立中: "《国家级名老中医临床经验实录丛书 叶传蕙肾病临证实录》", 30 November 2016, 中国医药科技出版社 * |
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Application publication date: 20191129 |