CN110495610A - A kind of collagen composition and preparation method thereof - Google Patents
A kind of collagen composition and preparation method thereof Download PDFInfo
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- CN110495610A CN110495610A CN201910699839.1A CN201910699839A CN110495610A CN 110495610 A CN110495610 A CN 110495610A CN 201910699839 A CN201910699839 A CN 201910699839A CN 110495610 A CN110495610 A CN 110495610A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 61
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 55
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 49
- 239000000843 powder Substances 0.000 claims abstract description 32
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims abstract description 31
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 28
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- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
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- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- 238000003786 synthesis reaction Methods 0.000 description 1
- 229920002258 tannic acid Polymers 0.000 description 1
- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 1
- 229940033123 tannic acid Drugs 0.000 description 1
- 235000015523 tannic acid Nutrition 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 238000002137 ultrasound extraction Methods 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of collagen compositions, including following components by weight: 0.2-15 parts of polypeptides, 0.2-15 parts of natural components, complement to 100 parts of auxiliary materials at 0.2-8 portions of oligosaccharide；Wherein the molecular weight of polypeptide is 500-1000Da, including collagen peptide and U.S. rattan fruit peptide；The oligosaccharide includes stachyose and oligofructose, and the natural component includes seabuckthorn fruit powder, line leaf money flower and cortex cinnamomi.The collagen composition appearance clear, shelf-stable, can effective skin maintenance and cosmetic benefits, remove free radical, improve skin state, improve skin water and moisten ruddy degree.The present invention also provides the preparation methods of the collagen composition.
Description
Technical field
The present invention relates to food with heath caring and beautifying function technical fields, and in particular to a kind of collagen composition and its preparation side
Method.
Background technique
According to CTR " report of nutrient and healthcare products industrial trend ", women accounts for the 60% of the health care product consumer group, and women is main
Consumption is the type of skin-care functional.Cosmetic health product has been evolved into an important branch of food.Cosmetic health product,
A kind of health food in order to reach the interior purpose for adjusting beauty and development & production, be by the adjusting in human body in function,
Make body interior function and external environment relative equilibrium, then be aided with external beauty means and support within reaching it is outer, inside and outside minor
Purpose.As female consumption level and health care consciousness are continuously improved, flourishing for beauty and health care industry has been driven.Associated mechanisms
In recent years beauty and health care industry market scale is gone up with 20% speedup for investigation, prediction to the market of aesthetic health care food industry in 2022
Capacity can achieve 23,000,000,000.
Research finds that pressure causes extended sleep insufficient, can make skin over fatigue, moisture and flexibility decrease, dull nothing
Light；Immanent electromagnetic wave in life, it is long-term in face of computer screen, smoke, expose the medium reason of environment in air pollution to the open air,
It can generate free radicals, lead to keratoderma aging；Skin metabolism is influenced, the symptoms such as coarse, dark yellow and microgroove go out therewith
It is existing.The appearance of cosmetic health product, which has evaded cosmetics only, makes one external beautiful, focuses on the internal physiological by adjusting people
Mechanism makes one the beauty for reaching nature.
Collagen peptide is a kind of common raw material in beauty and health care field, and some researches show that collagen peptide can be improved
The thickness of fibroblastic density and collagenous fibres in skin corium, improves the ratio of decorin, so as to improve skin
Mechanical strength.Have former protein food, beverage and skin care products currently on the market, brag about mostly collagen total amount how much
Gram, this is a kind of misleading, then a large amount of collagen, if the effect for also not having application cannot effectively be absorbed.
Summary of the invention
For overcome the deficiencies in the prior art, one of the objects of the present invention is to provide a kind of with beautifying face and moistering lotion effect
Composition, change composition have delay collagen peptide degradation, promote collagen peptide absorb, while have adjust enteron aisle balance
Composition.
The second object of the present invention is to provide the preparation method of the collagen composition.The process employs improve to plant
The method that object effective component extracts extracting rate, collagen composition obtained are in drink form.
An object of the present invention adopts the following technical scheme that realization:
A kind of collagen composition, including following components by weight: 0.2-15 parts of polypeptides, 0.2-8 parts it is oligomeric
Sugar, complements to 100 parts of auxiliary materials at 0.2-15 parts of natural components；Wherein the molecular weight of polypeptide is 500-1000Da, including collagen egg
White peptide and U.S. rattan fruit peptide；Oligosaccharide includes stachyose and oligofructose, and natural component includes seabuckthorn fruit powder, line leaf money flower and meat
Osmanthus.
The polypeptide that the collagen composition with molecular weight is 500-1000Da, is easy to absorb, provides for body and is easy to inhale
The small-molecular peptides of receipts promote skin moisturizing water conservation, improve elasticity of skin and moistening；Use stachyose, oligofructose to be oligomeric
Sugar promotes intestines and stomach strain balance to adjust enteron aisle ecology；Using the natural materials with bioactive substance, including activity
Ketone, phenols, organic acid, vitamin and microelement etc. promote body metabolism, anti-oxidant and toxin expelling.
It further, further include 0.01-4 parts of chitosans.
Further, including following components by weight: 0.1-8 parts of collagen peptides, 0.1-4 parts of U.S. rattan fruit peptides,
0.1-2 parts of stachyoses, 0.1-3 parts of oligofructose, 0.1-4 parts of seabuckthorn fruit powders, 0.1-4 parts of line leaf broom tops, 0.1-2 portions of cortex cinnamomis,
0.01-2 parts of chitosans and supply 100 parts of auxiliary materials.
Further, including following components by weight: 1-4 parts of collagen peptides, 1-2 parts of U.S. rattan fruit peptides, 0.5-1
Part stachyose, 1-2 parts of oligofructose, 1-2 parts of seabuckthorn fruit powders, 1-2 parts of line leaf broom tops, 0.5-1 portions of cortex cinnamomis, 0.1-1 parts of shells are poly-
Sugar and supply 100 parts of auxiliary materials.
Further, auxiliary material includes acid, sweetener, essence and water.
Further, acid is citric acid or malic acid；Sweetener is one in xylitol, antierythrite and white granulated sugar
Kind is two or more.
The second object of the present invention adopts the following technical scheme that realization:
A kind of preparation method of above-mentioned collagen composition, comprising:
1) line leaf broom top and cortex cinnamomi are added into 70-90 DEG C of heating water bath of water respectively, filters, obtains the first feed liquid；
2) seabuckthorn fruit powder is added into water dispersion, chitosan is added, ultrasonic wave extraction stands 1-8h, takes supernatant, filters, obtains
To the second feed liquid；
3) the first feed liquid is uniformly mixed with the second feed liquid, is filtered；
4) 40-60 DEG C is kept the temperature, formula remaining components are added, is mixed uniformly, filtering adds water constant volume；
5) cooling, obtain collagen composition.
Further, step 1), 2) and 3) in, filtering is filtered using 300-500 mesh filter screen, and in step 4), filtering is adopted
With multilayer 300-500 mesh filter plate.
Further, in step 3), first material is divided 2-3 times with second material to be mixed.
Further, in step 5), after cooling, filling, sterilizing, packaging obtain collagen composition.
Compared with prior art, the beneficial effects of the present invention are:
Collagen composition provided by the invention is used using collagen peptide and U.S. rattan fruit peptide as the main of small-molecular peptides
The seabuckthorn fruit powder with toxin-expulsion oxidation-resistance function and line leaf gold are added using stachyose, oligofructose as oligosaccharide source in source
Sparrow flower, and the cortex cinnamomi with middle benefit gas kidney tonifying, multiple-effect unification, promote immune promotion and the metabolic balance of human body, hold beauty to support
Face.
Collagen composition provided by the invention, collagen peptide and U.S. rattan fruit peptide are absorbed by the body rate height, can be formed
Long-acting elastic force moisturizing net keeps cell connection closer to reduce water loss, and it is heavy to accelerate rate of metabolism, reduction melanin
Product.
Line leaf broom top and cortex cinnamomi are first carried out water and mentioned, also accelerate precipitating using chitosan by preparation method of the invention
Mode water proposes the effective component in seabuckthorn fruit powder, filters and uses, and the ingredient for playing drug effect can be made to be released effectively, be conducive to human body suction
It receives；Remaining component includes collagen peptide, U.S. rattan fruit peptide, stachyose and oligofructose as main and plays trophism ingredient
Effect, then be directly to make an addition to system, trophism ingredient can be effectively ensured and be not damaged, so that the collagen composition has
Preferable product condition.
Specific embodiment
In the following, being described further in conjunction with specific embodiment to the present invention, it should be noted that is do not collided
Under the premise of, new embodiment can be formed between various embodiments described below or between each technical characteristic in any combination.This reality
Apply employed in example to material be commercially available.
It is specific embodiment of the present invention below, used raw material, equipment etc. remove special limit in the following embodiments
It can be obtained by buying pattern outside fixed.
The present invention provides a kind of collagen composition, including following components by weight: 0.2-15 parts of polypeptides,
0.2-8 portions of oligosaccharide, complement to 100 parts of auxiliary materials at 0.2-15 parts of natural components；Wherein the molecular weight of polypeptide is 400-1000Da,
Including collagen peptide and U.S. rattan fruit peptide；The oligosaccharide includes stachyose and oligofructose, and the natural component includes sea-buckthorn
Fruit powder, line leaf money flower and cortex cinnamomi.
The present invention provides a kind of collagen composition, including following components by weight: 1-4 parts of collagens
Peptide, 1-2 parts of U.S. rattan fruit peptides, 0.5-1 parts of stachyoses, 1-2 parts of oligofructose, 1-2 parts of seabuckthorn fruit powders, 1-2 parts of line leaf broom tops,
0.5-1 portions of cortex cinnamomis, 0.1-1 parts of chitosans and supply 100 parts of auxiliary materials.It wherein include 5-10 portions of white granulated sugars, 0.4-0.6 parts in auxiliary material
Citric acid, 0.2-0.3 part essence and complement to 100 parts of purified water.
The polypeptide moiety collagen peptide of the molecular weight ranges and U.S. rattan fruit peptide can preferably be absorbed by the body, to promote
Into metabolism, melanin deposition is prevented；Stachyose and oligofructose can effectively facilitate intestines as main intake property oligosaccharide
The growth of the probiotics such as road Bifidobacterium promotes intestines peristalsis, and softer stool improves constipation.By defecation, poison in vivo is discharged
Element；Line leaf broom top and seabuckthorn fruit powder provide bioactive ingredients as free radical resisting ingredient, promote protein peptides, U.S. rattan fruit peptide
Absorption.
Seabuckthorn fruit powder has vitamin abundant, phenols active material, ketone active material, organic acid and microelement
Deng can effectively clear interior free yl, wrinkle resistance, whitening and anti-oxidant acts synergistically with collagen peptide, U.S. rattan fruit peptide；Cortex cinnamomi
Effective component includes volatile oil and meat aldehyde, and volatile oil has stronger reproducibility, antioxidant activity and certain removing free radical
Ability, cinnamic acid may pass through inhibit UVA irradiation after fibroblast mitogen-activated protein kinase (MAPK) signal path
Activation inhibit the expression of Fibroblast collagenase (MMP-1) and MMP-3, reduce collagen degradation, delaying skin light is old
Change；SOD is enriched in line leaf broom top can promote the synthesis of collagen, elastin laminin, be conducive to improve skin quality, with polypeptide moiety
Concertedness effect.
The present invention also provides a kind of preparation methods of above-mentioned collagen composition, comprising:
1) line leaf broom top and cortex cinnamomi are added into 70-90 DEG C of heating water bath of water respectively, filters, obtains the first feed liquid；
2) seabuckthorn fruit powder is added into water dispersion, chitosan is added, ultrasonic extraction stands 1-8h, takes supernatant, filters, obtains
Second feed liquid；
3) the first feed liquid is uniformly mixed with the second feed liquid, is filtered；
4) 40-60 DEG C is kept the temperature, formula remaining components are added, is mixed uniformly, filtering adds water constant volume；
5) cooling, obtain collagen composition.
In the preparation method, adds water to carry out water-bath infusion respectively line leaf broom top and cortex cinnamomi respectively, can effectively facilitate
The release of the effective components such as ethereal oil；Seabuckthorn fruit powder remains more pulp, colloid after being dispersed in water, chitosan is added can
To accelerate the precipitating of pulp and colloid；Line leaf broom top after merging filtrate, tannic acid that may be present can be with seabuckthorn fruit powder in cortex cinnamomi
Remaining chitosan generates precipitating in filtrate, can guarantee the clarity of finished product after filtering.
Embodiment 1:
A kind of collagen composition is made including following components by weight: 0.1 part of collagen peptide, 8 parts
U.S. rattan fruit peptide, 0.1 part of stachyose, 3 parts of oligofructose, 0.1 part of seabuckthorn fruit powder, 4 parts of line leaf broom tops, 2 portions of cortex cinnamomis, 0.01 part
Chitosan, 10 portions of white granulated sugars, 0.4 part of citric acid, 0.3 part of essence and the purified water for complementing to 100 parts.
The method for preparing the collagen composition, comprising:
1) line leaf broom top and cortex cinnamomi are added into 10 parts of water, 80 DEG C of heating water baths respectively, is filtered, is obtained using 400 mesh filter screen
First feed liquid；
2) seabuckthorn fruit powder is added into 5 parts of water dispersions, chitosan is added, uses NingBo XinZhi Biology Science Co., Ltd
Scientz-30T ultrasonic extractor extracts, and setting working frequency is 25KHz, and setting ultrasonic power is 2000w, and extracting solution is quiet
It sets 4 hours, stands 3h, take supernatant, filtered using 400 mesh filter screen, obtain the second feed liquid；
3) the first feed liquid is uniformly mixed in three times with the second feed liquid, is filtered using 400 mesh filter screen；
4) 50 DEG C are kept the temperature, formula remaining components are added, mixes uniformly, using 10 layer of 400 mesh filter plate, adds water fixed
Hold；
5) cooling, filling, sterilizing, packaging obtain collagen composition.
Embodiment 2:
A kind of collagen composition is made including following components by weight: 8 parts of collagen peptides, 0.1 part
U.S. rattan fruit peptide, 2 parts of stachyoses, 0.1 part of oligofructose, 4 parts of seabuckthorn fruit powders, 0.1 part of line leaf broom top, 0.1 portion of cortex cinnamomi, 2 parts of shells
Glycan, 5 portions of white granulated sugars, 0.4 part of citric acid, 0.2 part of essence and the purified water for complementing to 100 parts.
The method for preparing the collagen composition, comprising:
1) line leaf broom top and cortex cinnamomi are added into 5 parts of water, 80 DEG C of heating water baths respectively, is filtered, is obtained using 400 mesh filter screen
First feed liquid；
2) seabuckthorn fruit powder is added into 15 parts of water dispersions, chitosan is added, uses NingBo XinZhi Biology Science Co., Ltd
Scientz-30T ultrasonic extractor extracts, and setting working frequency is 25KHz, and setting ultrasonic power is 2000w, and extracting solution is quiet
It sets 4 hours, stands 3h, take supernatant, filtered using 400 mesh filter screen, obtain the second feed liquid；
3) the first feed liquid is uniformly mixed in three times with the second feed liquid, is filtered using 400 mesh filter screen；
4) 50 DEG C are kept the temperature, formula remaining components are added, mixes uniformly, using 10 layer of 400 mesh filter plate, adds water fixed
Hold；
5) cooling, filling, sterilizing, packaging obtain collagen composition.
Embodiment 3:
A kind of collagen composition is made including following components by weight: 4 parts of collagen peptides, 1 part of beauty
Rattan fruit peptide, 1 part of stachyose, 1 part of oligofructose, 2 parts of seabuckthorn fruit powders, 1 part of line leaf broom top, 0.5 portion of cortex cinnamomi, 1 part of chitosan,
7.5 portions of white granulated sugars, 0.5 part of citric acid, 0.25 part of essence and the purified water for complementing to 100 parts.
The method for preparing the collagen composition, comprising:
1) line leaf broom top and cortex cinnamomi are added into 5 parts of water, 80 DEG C of heating water baths respectively, is filtered, is obtained using 400 mesh filter screen
First feed liquid；
2) seabuckthorn fruit powder is added into 10 parts of water dispersions, chitosan is added, uses NingBo XinZhi Biology Science Co., Ltd
Scientz-30T ultrasonic extractor extracts, and setting working frequency is 25KHz, and setting ultrasonic power is 2000w, and extracting solution is quiet
It sets 4 hours, stands 3h, take supernatant, filtered using 400 mesh filter screen, obtain the second feed liquid；
3) the first feed liquid is uniformly mixed in three times with the second feed liquid, is filtered using 400 mesh filter screen；
4) 50 DEG C are kept the temperature, formula remaining components are added, mixes uniformly, using 10 layer of 400 mesh filter plate, adds water fixed
Hold；
5) cooling, filling, sterilizing, packaging obtain collagen composition.
Embodiment 4:
A kind of collagen composition is made including following components by weight: 1 part of collagen peptide, 2 parts of beauty
Rattan fruit peptide, 0.5 part of stachyose, 2 parts of oligofructose, 1 part of seabuckthorn fruit powder, 2 parts of line leaf broom tops, 1 portion of cortex cinnamomi, 0.1 part of shell are poly-
Sugar, 7.5 portions of white granulated sugars, 0.5 part of citric acid, 0.25 part of essence and the purified water for complementing to 100 parts.
The method for preparing the collagen composition, comprising:
1) line leaf broom top and cortex cinnamomi are added into 15 parts of water, 80 DEG C of heating water baths respectively, is filtered, is obtained using 400 mesh filter screen
First feed liquid；
2) seabuckthorn fruit powder is added into 5 parts of water dispersions, chitosan is added, uses NingBo XinZhi Biology Science Co., Ltd
Scientz-30T ultrasonic extractor extracts, and setting working frequency is 25KHz, and setting ultrasonic power is 2000w, and extracting solution is quiet
It sets 4 hours, stands 3h, take supernatant, filtered using 400 mesh filter screen, obtain the second feed liquid；
3) the first feed liquid is uniformly mixed in three times with the second feed liquid, is filtered using 400 mesh filter screen；
4) 50 DEG C are kept the temperature, formula remaining components are added, mixes uniformly, using 10 layer of 400 mesh filter plate, adds water fixed
Hold；
5) cooling, filling, sterilizing, packaging obtain collagen composition.
Embodiment 5:
A kind of collagen composition is made including following components by weight: 3 parts of collagen peptides, 1.5 parts
U.S. rattan fruit peptide, 0.8 part of stachyose, 1.5 parts of oligofructose, 1.5 parts of seabuckthorn fruit powders, 1.5 parts of line leaf broom tops, 0.8 portion of cortex cinnamomi,
0.5 part of chitosan, 7.5 portions of white granulated sugars, 0.5 part of citric acid, 0.25 part of essence and the purified water for complementing to 100 parts.
The method for preparing the collagen composition, comprising:
1) line leaf broom top and cortex cinnamomi are added into 10 parts of water, 80 DEG C of heating water baths respectively, is filtered, is obtained using 400 mesh filter screen
First feed liquid；
2) seabuckthorn fruit powder is added into 5 parts of water dispersions, chitosan is added, uses NingBo XinZhi Biology Science Co., Ltd
Scientz-30T ultrasonic extractor extracts, and setting working frequency is 25KHz, and setting ultrasonic power is 2000w, and extracting solution is quiet
It sets 4 hours, stands 3h, take supernatant, filtered using 400 mesh filter screen, obtain the second feed liquid；
3) the first feed liquid is uniformly mixed in three times with the second feed liquid, is filtered using 400 mesh filter screen；
4) 50 DEG C are kept the temperature, formula remaining components are added, mixes uniformly, using 10 layer of 400 mesh filter plate, adds water fixed
Hold；
5) cooling, filling, sterilizing, packaging obtain collagen composition.
The collagen composition that embodiment 1-5 is obtained, it is proposed that packing specification be 30mL/ branch, it is proposed that amount be
Adult 2 times a day, 1 wraps every time.
Comparative example 1:
A kind of collagen composition is made including following components by weight: 3 parts of collagen peptides, 1.5 parts
U.S. rattan fruit peptide, 0.8 part of stachyose, 1.5 parts of oligofructose, 1.5 parts of seabuckthorn fruit powders, 1.5 parts of line leaf broom tops, 0.8 portion of cortex cinnamomi,
7.5 portions of white granulated sugars, 0.5 part of citric acid, 0.25 part of essence and the purified water for complementing to 100 parts.
The method for preparing the collagen composition, comprising:
1) line leaf broom top and cortex cinnamomi are added into 10 parts of water, 80 DEG C of heating water baths respectively, is filtered, is obtained using 400 mesh filter screen
First feed liquid；
2) seabuckthorn fruit powder is added into 5 parts of water dispersions, uses NingBo XinZhi Biology Science Co., Ltd Scientz-30T
Ultrasonic extractor extracts, and setting working frequency is 25KHz, and setting ultrasonic power is 2000w, and extracting solution stands 4 hours, quiet
3h is set, supernatant is taken, is filtered using 400 mesh filter screen, obtains the second feed liquid；
3) the first feed liquid is uniformly mixed in three times with the second feed liquid, is filtered using 400 mesh filter screen；
4) 50 DEG C are kept the temperature, formula remaining components are added, mixes uniformly, using 10 layer of 400 mesh filter plate, adds water fixed
Hold；
5) cooling, filling, sterilizing, packaging obtain collagen composition.
Comparative example 2:
A kind of collagen composition is made including following components by weight: 3 parts of collagen peptides, 1.5 parts
U.S. rattan fruit peptide, 0.8 part of stachyose, 1.5 parts of oligofructose, 1.5 parts of seabuckthorn fruit powders, 1.5 parts of line leaf broom tops, 0.8 portion of cortex cinnamomi,
0.5 part of chitosan, 7.5 portions of white granulated sugars, 0.5 part of citric acid, 0.25 part of essence and the purified water for complementing to 100 parts.
The method for preparing the collagen composition, comprising:
1) line leaf broom top and cortex cinnamomi are added into 10 parts of water, 80 DEG C of heating water baths respectively, is filtered, is obtained using 400 mesh filter screen
First feed liquid；
2) seabuckthorn fruit powder is added into 5 parts of water dispersions, chitosan is added, stand 4 hours, stood 3h, supernatant is taken, using 400
The filtering of mesh filter screen, obtains the second feed liquid；
3) the first feed liquid is uniformly mixed in three times with the second feed liquid, is filtered using 400 mesh filter screen；
4) 50 DEG C are kept the temperature, formula remaining components are added, mixes uniformly, using 10 layer of 400 mesh filter plate, adds water fixed
Hold；
5) cooling, filling, sterilizing, packaging obtain collagen composition.
The collagen composition that embodiment 1-5 is obtained, it is proposed that packing specification be 30mL/ branch, it is proposed that amount be
Adult 2 times a day, 1 wraps every time.
Effect assessment:
1, appearance character and stability
The collagen composition obtained by embodiment 1-5, comparative example 1 and 2 evaluates its appearance by naked eyes,
It is placed 3 months in the case where 40 DEG C ± 2 DEG C, relative humidity are 75% ± 5% illumination condition, and true temperature and humidity is supervised
It surveys.1st month during test, 2 months, 3 the end of month separately sampled 1 time, detected by stability high spot reviews project.Knot
Fruit is as shown in the table:
1 appearance character of table and stability
As seen from the above table, after by shell adding glycan, the bright degree for improving oral solution can be imitated, and passes through ultrasonic in combination shell
The peptizaiton of glycan can improve to concertedness the bright degree of oral solution.
2, sensory evaluation
The collagen composition obtained by embodiment 1-5 and comparative example 1 and 2, by 10 sensory evaluation Shi Suiji to it
Quality sense, sugariness, bitterness degree carry out the comprehensive score that 1-10 divides, as a result as shown in the table:
2 sensory evaluation of table
| Embodiment | Quality sense | Sugariness | Bitter degree |
| Embodiment 1 | 8.3 | 8.9 | 2.4 |
| Embodiment 2 | 8.2 | 7.2 | 2.8 |
| Embodiment 3 | 8.6 | 8.1 | 2.2 |
| Embodiment 4 | 8.7 | 8.2 | 2.5 |
| Embodiment 5 | 8.6 | 8.0 | 2.3 |
| Comparative example 1 | 7.2 | 7.4 | 3.6 |
| Comparative example 2 | 7.9 | 7.6 | 3.7 |
As seen from the above table, the collagen composition obtained by the application has any clear astringent taste in sweet tea, agreeably sweet,
Edible quality sense is preferable, smooth palatable.
3. zoopery
SPF grades of 22~26g of SD kunming mice weight are selected, 120 are divided six groups, every group 20 at random.It is divided into blank control
Group (is irradiated, distilled water stomach-filling) without ultraviolet light, model control group (ultraviolet irradiation, distilled water stomach-filling), and positive controls are (purple
External exposure, 5% collagen solution), example 1 group (ultraviolet light irradiation, 1 sample stomach-filling of embodiment), 2 (ultraviolet lamp of embodiment
Irradiation, 2 sample stomach-filling of embodiment；), 3 groups of embodiment (ultraviolet light irradiation, 3 sample stomach-filling of embodiment).Each group mouse first carries out in advance
Anti- property stomach-filling two weeks, mouse was lost hair or feathers with 6% vulcanized sodium alcoholic solution daily and carries out ultraviolet irradiation since third week,
Each group mouse uses this group of sample 2ml stomach-filling before 30min before ultraviolet irradiation daily.The daily ultraviolet irradiation 2h that carries out establishes skin
Aging model, Continuous irradiation 60 days, induced subacute aging model, the 61st day execution mouse measured back of mice skin histology
Superoxide dismutase activity (SOD), mda content (MDA), hydroxyproline (HYP) content in homogenate.
As a result indicate that example 1 group, 2 groups of embodiment, 3 groups of samples of embodiment compare other groups can improve skin in various degree
SOD vigor in skin reduces MDA content, improves the content of hydroxyproline in mouse skin, and all has significant difference (P <
0.05).Its as the result is shown beautifying face and moistering lotion collagen composition can delay skin aging, be significantly improved effect to skin
Fruit.
SOD, MDA, HYP content in 3. stomach-filling oral solution each group mice skin tissue of table
In conclusion beautifying face and moistering lotion collagen composition provided by the present application has the effect of preferable beautifying face and moistering lotion.
The above embodiment is only the preferred embodiment of the present invention, and the scope of protection of the present invention is not limited thereto,
The variation and replacement for any unsubstantiality that those skilled in the art is done on the basis of the present invention belong to institute of the present invention
Claimed range.
Claims (10)
1. a kind of collagen composition, which is characterized in that including following components by weight: 0.2-15 parts of polypeptides,
0.2-8 portions of oligosaccharide, complement to 100 parts of auxiliary materials at 0.2-15 parts of natural components；Wherein the molecular weight of polypeptide is 500-1000Da,
Including collagen peptide and U.S. rattan fruit peptide；The oligosaccharide includes stachyose and oligofructose, and the natural component includes sea-buckthorn
Fruit powder, line leaf money flower and cortex cinnamomi.
2. collagen composition as described in claim 1, which is characterized in that further include 0.01-4 parts of chitosans.
3. collagen composition as claimed in claim 2, which is characterized in that including following components by weight:
0.1-8 parts of collagen peptides, 0.1-4 parts of U.S. rattan fruit peptides, 0.1-2 parts of stachyoses, 0.1-3 parts of oligofructose, 0.1-4 parts of fructus hippophaes
Powder, 0.1-4 parts of line leaf broom tops, 0.1-2 portions of cortex cinnamomis, 0.01-2 parts of chitosans and supply 100 parts of auxiliary materials.
4. a kind of collagen composition as claimed in claim 2, which is characterized in that including by weight with the following group
Point: 1-4 parts of collagen peptides, 1-2 parts of U.S. rattan fruit peptides, 0.5-1 parts of stachyoses, 1-2 parts of oligofructose, 1-2 parts of seabuckthorn fruit powders, 1-
2 parts of line leaf broom tops, 0.5-1 portions of cortex cinnamomis, 0.1-1 parts of chitosans and supply 100 parts of auxiliary materials.
5. a kind of collagen composition as described in claim 1, which is characterized in that the auxiliary material includes acid, sweet taste
Agent, essence and water.
6. a kind of collagen composition as claimed in claim 5, which is characterized in that the acid is citric acid or apple
Acid；The sweetener is one or more of xylitol, antierythrite and white granulated sugar.
7. a kind of preparation method of collagen composition as claimed in any one of claims 1 to 6 characterized by comprising
1) line leaf broom top and cortex cinnamomi are added into 70-90 DEG C of heating water bath of water respectively, filters, obtains the first feed liquid；
2) seabuckthorn fruit powder is added into water dispersion, chitosan is added, ultrasonic wave extraction stands 1-8h, takes supernatant, filters, and obtains the
Two feed liquids；
3) the first feed liquid is uniformly mixed with the second feed liquid, is filtered；
4) 40-60 DEG C is kept the temperature, formula remaining components are added, is mixed uniformly, filtering adds water constant volume；
5) cooling, obtain collagen composition.
8. preparation method as claimed in claim 7, which is characterized in that step 1), 2) and 3) in, filtering uses 300-500 mesh
Filter screen filters, and in step 4), filtering uses multilayer 300-500 mesh filter plate.
9. preparation method as claimed in claim 7, which is characterized in that in step 3), first material and second material are divided 2-3 times
Mixing.
10. preparation method as claimed in claim 7, which is characterized in that in step 5), after cooling, filling, sterilizing, packaging are obtained
To collagen composition.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111903889A (en) * | 2020-08-12 | 2020-11-10 | 安徽盛美诺生物技术有限公司 | Formula of double-peptide combined skin-beautifying solid beverage |
| CN112956703A (en) * | 2021-04-09 | 2021-06-15 | 果畅(苏州)健康科技有限公司 | Collagen peptide health food and production method thereof |
| CN113116738A (en) * | 2019-12-31 | 2021-07-16 | 新生活化妆品科技(上海)有限公司 | External additive, application thereof and skin external product |
| CN116173291A (en) * | 2023-03-08 | 2023-05-30 | 重庆医科大学附属第二医院 | Chitosan recombinant humanized collagen gel and preparation method and application thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106360740A (en) * | 2016-08-31 | 2017-02-01 | 安徽旺润生物科技有限公司 | Feature beautifying and skin nourishing nutrient composition |
| CN106912961A (en) * | 2017-03-07 | 2017-07-04 | 沈阳易生活生物科技有限公司 | A kind of collagen peptide and its manufacture method |
| CN108450961A (en) * | 2018-01-24 | 2018-08-28 | 佛山科学技术学院 | A kind of U.S.'s rattan fruit small molecule Gly-His-Lys and preparation method thereof |
| CN109198316A (en) * | 2018-09-11 | 2019-01-15 | 杭州德能生物医药有限公司 | A kind of formula of draft drink |
| CN110037268A (en) * | 2019-04-24 | 2019-07-23 | 广州市洛天生物科技有限责任公司 | A kind of beautifying face and moistering lotion jelly and preparation method thereof improving sleep |
-
2019
- 2019-07-31 CN CN201910699839.1A patent/CN110495610A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106360740A (en) * | 2016-08-31 | 2017-02-01 | 安徽旺润生物科技有限公司 | Feature beautifying and skin nourishing nutrient composition |
| CN106912961A (en) * | 2017-03-07 | 2017-07-04 | 沈阳易生活生物科技有限公司 | A kind of collagen peptide and its manufacture method |
| CN108450961A (en) * | 2018-01-24 | 2018-08-28 | 佛山科学技术学院 | A kind of U.S.'s rattan fruit small molecule Gly-His-Lys and preparation method thereof |
| CN109198316A (en) * | 2018-09-11 | 2019-01-15 | 杭州德能生物医药有限公司 | A kind of formula of draft drink |
| CN110037268A (en) * | 2019-04-24 | 2019-07-23 | 广州市洛天生物科技有限责任公司 | A kind of beautifying face and moistering lotion jelly and preparation method thereof improving sleep |
Non-Patent Citations (5)
| Title |
|---|
| 丘泰球等: "声场对胶体物系絮凝分离作用的研究", 《华南理工大学学报(自然科学版)》, no. 12, 28 December 1999 (1999-12-28), pages 96 * |
| 周凌等: "肉桂醛对UVA照射后体外成纤维细胞表达MMP-1,MMP-3和MAPK信号的影响", 《中国皮肤性病学杂志》, no. 02, 15 February 2015 (2015-02-15), pages 114 * |
| 大飞: "美藤果蛋白肽（美藤果肽）--来自云南的新蛋白质植物肽", 《大飞食品原料信息中心》, 7 September 2018 (2018-09-07), pages 1 - 2 * |
| 张建伟等: "壳聚糖对银杏叶水提液的絮凝工艺研究", 《化学工程》, no. 02, 15 February 2008 (2008-02-15) * |
| 陈成等: "《岐黄医药纵横》", 31 January 2013, 甘肃科学技术出版社, pages: 14 * |
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| CN113116738B (en) * | 2019-12-31 | 2022-09-02 | 新生活化妆品科技(上海)有限公司 | External additive, application thereof and skin external product |
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