CN110491231A - A kind of biomechanics experiment simulator of endovascular stent implantation - Google Patents
A kind of biomechanics experiment simulator of endovascular stent implantation Download PDFInfo
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- CN110491231A CN110491231A CN201910777487.7A CN201910777487A CN110491231A CN 110491231 A CN110491231 A CN 110491231A CN 201910777487 A CN201910777487 A CN 201910777487A CN 110491231 A CN110491231 A CN 110491231A
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B9/00—Simulators for teaching or training purposes
Abstract
The invention discloses a kind of biomechanics experiment simulators of endovascular stent implantation, it is related to medical instrument the field of test technology, it includes computer, peristaltic pump, connecting tube, liquid reserve tank, arteries model, pressure regulator and vein blood vessel model: the peristaltic pump is connected with connecting tube, one end of the connecting tube is connected with liquid reserve tank, and the other end of the connecting tube is connected with arteries model.The biomechanics experiment simulator of endovascular stent implantation, by the way that two lesion vessels models are arranged, a lesion vessels model is implanted into bracket wherein, another not implantable intravascular bracket, detect two lesion vessels model datas using three pressure sensors, by comparing and analyzing, can accurately be illustrated the case where obtaining suffered organism pressure variation after implantation bracket, it can accurately, significantly reflect the variation of data in this way, to improve the accuracy of present apparatus data.
Description
Technical field
The present invention relates to medical instrument the field of test technology, specially a kind of biomechanics experiment of endovascular stent implantation
Simulator.
Background technique
Intravascular stenting can be applied to move or the limitation of venous system is narrow or occludes, and rebuilds blood vessel access
And abnormal hemodynamics are corrected, using technologies such as puncture, conduit, inferior vena cava balloon dilation formation and internal metal rack mergings, make
Narrow, occlusion blood vessel or cavity expansion are led to again, solve a kind of technology of traditional operation blind area.
Before bracket carries out zoopery, clinical test in the blood vessels, endovascular stent can carry out approximate true in vitro
Real situation simulation implantation experiment tests its mechanical property, this by for the design of endovascular stent and research and development provide it is especially intuitive and
Objective appraisal opinion.Existing endovascular stent implantation experiment simulator, when being implanted into inner support, by acquisition bracket into
Enter the data of intravascular organism pressure variation, the data for obtaining all data of stenter to implant, but acquiring in this way not can guarantee
The accuracy of data causes experiment analogue data to generate error, to reduce the accuracy of experimental simulation device, it is possible to band
Carry out serious malpractice.
Summary of the invention
(1) the technical issues of solving
In view of the deficiencies of the prior art, the present invention provides a kind of biomechanics experiments of endovascular stent implantation to simulate dress
It sets, solves existing endovascular stent implantation experiment simulator, when being implanted into inner support, enter blood vessel by acquiring bracket
The data of interior organism pressure variation, the data for obtaining all data of stenter to implant, but acquiring in this way not can guarantee data
Accuracy causes experiment analogue data to generate error, to reduce the accuracy of experimental simulation device, it is possible to bring serious
The problem of malpractice.
(2) technical solution
To achieve the above objectives, the technical solution adopted by the present invention is that: a kind of biomethanics of endovascular stent implantation is real
Test simulator, including computer, peristaltic pump, connecting tube, liquid reserve tank, arteries model, pressure regulator and vein blood vessel
Model:
The peristaltic pump is connected with connecting tube, and one end of the connecting tube is connected with liquid reserve tank, the connecting tube
The other end is connected with arteries model, and the other end of the arteries model passes through pressure regulator and venous blood pipe die
One end of type is connected, and the other end of the vein blood vessel model is connected with the upper surface of liquid reserve tank；
The arteries model includes two branch vessel models, and is provided with lesion in two branch vessel models
Vascular pattern, and it is provided with high frequency camera shooting machine on one of lesion vessels model, and be provided with the lesion blood of high frequency camera shooting machine
It is connected respectively with two pressure sensors at left and right sides of tube model, and the right side of another lesion vessels model and pressure sensing
Device is connected, and the quantity of pressure sensor is three, and is located in one of the right side of lesion vessels model and establishes channel
One end of pipe is connected, and the other end for establishing tube channel is connected with interface is punctured；
Flowmeter is provided in the arteries model, the flowmeter is located at the right side of branch vessel model, and flows
Meter adopts the data of blood flow in arteries model, by signal imitation comparative analysis, shows artificial blood flow waves
Shape figure；
The computer is analyzed and is arranged by acquisition blood flow data, output ripple frequency, signal amplitude
Instruction is converted by DA data analog signal, dependent instruction is transmitted in peristaltic pump, and blood flow, and three pressure are controlled
The data that sensor acquires pressure change in two lesion vessels models show pressure by comparing and analyzing between each other
Waveform diagram；
The high frequency camera shooting machine captured in real-time lesion vessels inner support transports, is implanted into, expanding, support process, by image
Processing module processing and parsing, show the image of support motion.
Preferably, the material of the lesion vessels model is transparent silicone rubber, the long 12-15cm of blood vessel, wall thickness 2.4-
3.7mm, entrance and exit section interior diameter are 3-6cm.
Preferably, artificial blood is stored in the liquid reserve tank, artificial blood is the artificial synthesized fluorine with function of carrying oxygen
Carbon compound, the colloid submicron emulsion that fluorocarbon emulsion is made of perfluorochemical have good oxygen carrying capacity, certain
Under the conditions of concentration and partial pressure of oxygen, oxygen solubility is 20 times of water, 2 times higher than blood.
Preferably, the bracket generates plastic deformation in pressure air bag inflating pressure, and after pressure air bag is deflated, bracket is still
Expansion state is kept, and the material of bracket should have low yield stress and high elastic modulus, to prop up after pressure air bag is inflated
Frame elastical retraction is small.
Preferably, the pressure regulator adjusts the pressure of blood between arteries model and vein blood vessel model.
(3) beneficial effect
The beneficial effects of the present invention are:
1, the biomechanics experiment simulator of endovascular stent implantation, by the way that two lesion vessels models, In is arranged
Wherein a lesion vessels model is implanted into bracket, and another not implantable intravascular bracket utilizes three pressure sensors detections two
Lesion vessels model data, by comparing and analyzing, the suffered organism pressure after obtaining implantation bracket that can accurately be illustrated
The case where variation, can accurately, significantly reflect the variation of data in this way, to improve the accuracy of present apparatus data.
2, the biomechanics experiment simulator of endovascular stent implantation is used by setting computer and peristaltic pump
The specific data of the blood flow of acquisition, calculate and analyze ripple frequency and signal amplitude, turn by DA data analog signal
It changes, is transmitted in peristaltic pump, wriggling pump work, so that blood circulation is flowed in arteries model and vein blood vessel model, phase
As the analog simulation human bloodstream circulatory system, while blood flow is monitored using flowmeter.
3, the biomechanics experiment simulator of endovascular stent implantation, by the way that high frequency camera shooting machine is arranged, in implantation branch
During frame, it is able to observe that the overall process that bracket is transported, is implanted into, expands and is supported in the blood vessels, people is facilitated to adjust in time
Bracket is saved, it is convenient to bring to people's operation.
Detailed description of the invention
Fig. 1 is apparatus of the present invention overall structure diagram；
Fig. 2 is computer-controlled program flow diagram.
In figure: 1 computer, 2 peristaltic pumps, 3 connecting tubes, 4 liquid reserve tanks, 5 arteries models, 6 pressure regulators, 7 veins
Vascular pattern, 8 branch vessel models, 9 lesion vessels models, 10 high frequency camera shooting machines, 11 pressure sensors, 12 establish tube channel,
13 pressure sacculus, 14 flowmeters.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
As shown in Figs. 1-2, the present invention provides a kind of technical solution: a kind of biomechanics experiment mould of endovascular stent implantation
Quasi- device, including computer 1, peristaltic pump 2, connecting tube 3, liquid reserve tank 4, arteries model 5, pressure regulator 6 and venous blood
Tube model 7:
Peristaltic pump 2 is connected with connecting tube 3, and one end of connecting tube 3 is connected with liquid reserve tank 4, the other end of connecting tube 3 with
Arteries model 5 is connected, and the other end of arteries model 5 passes through one end of pressure regulator 6 and vein blood vessel model 7
It is connected, the other end of vein blood vessel model 7 is connected with the upper surface of liquid reserve tank 4；
Arteries model 5 includes two branch vessel models 8, and is provided with lesion in two branch vessel models 8
Vascular pattern 9, and it is provided with high frequency camera shooting machine 10 on one of lesion vessels model 9, and be provided with high frequency camera shooting machine 10
9 left and right sides of lesion vessels model is connected with two pressure sensors 11 respectively, and the right side of another lesion vessels model 9
It is connected with pressure sensor 11, and the quantity of pressure sensor 11 is three, and is located in one of lesion vessels model 9
Right side is connected with the one end for establishing tube channel 12, and the other end for establishing tube channel 12 is connected with interface 13 is punctured；
Flowmeter 14 is provided in arteries model 5, flowmeter 14 is located at the right side of branch vessel model 8, and flow
The data that meter 14 adopts blood flow in arteries model 5 show artificial blood flow waves by signal imitation comparative analysis
Shape figure；
Computer 1 is analyzed and is arranged by acquisition blood flow data, the finger of output ripple frequency, signal amplitude
It enables, is converted by DA data analog signal, dependent instruction is transmitted in peristaltic pump 2, control blood flow, and three pressure pass
The data that sensor 11 acquires pressure change in two lesion vessels models 9 show pressure by comparing and analyzing between each other
Waveform diagram；
10 captured in real-time lesion vessels inner support of high frequency camera shooting machine transports, is implanted into, expanding, support process, at image
Resume module and parsing are managed, shows the image of support motion.
The material of lesion vessels model 9 be transparent silicone rubber, the long 12-15cm of blood vessel, wall thickness 2.4-3.7mm, entrance and go out
Mouth section interior diameter is 3-6cm.
Artificial blood is stored in liquid reserve tank 4, artificial blood is the artificial synthesized fluorocarbons with function of carrying oxygen, fluorine
The colloid submicron emulsion that carbon is made of for blood perfluorochemical has good oxygen carrying capacity, in a certain concentration and oxygen
Under the conditions of pressure, oxygen solubility is 20 times of water, 2 times higher than blood.
Bracket generates plastic deformation in pressure air bag inflating pressure, and after pressure air bag is deflated, bracket still keeps expansion shape
State, and the material of bracket should have low yield stress and high elastic modulus, so that after pressure air bag is inflated, rack elasticity bounces back
It is small.
Pressure regulator 6 adjusts the pressure of blood between arteries model 5 and vein blood vessel model 7.
By the way that two lesion vessels models 9 are arranged, a lesion vessels model 9 is implanted into bracket wherein, and another is not
Implantable intravascular bracket detects two 9 data of lesion vessels model, by comparing and analyzing, energy using three pressure sensors 11
It is enough it is accurately clear obtain the case where suffered organism pressure after implantation bracket changes, can accurately, significantly reflect in this way
The variation of data, to improve the accuracy of present apparatus data.
It calculates using the specific data of the blood flow of acquisition by setting computer 1 and peristaltic pump 2 and analyzes arteries and veins
Dynamic frequency and signal amplitude are converted by DA data analog signal, are transmitted in peristaltic pump 2, and peristaltic pump 2 works, so that artery
Blood circulation is flowed in vascular pattern 5 and vein blood vessel model 7, the similar analog simulation human bloodstream circulatory system, simultaneously
Blood flow is monitored using flowmeter 14.
It is able to observe that bracket is transported in the blood vessels, planted during being implanted into bracket by the way that high frequency camera shooting machine 10 is arranged
The overall process for entering, expanding and supporting facilitates the timely adjusting bracket of people, and it is convenient to bring to people's operation.
Operating procedure of the invention are as follows:
S1, in use, people acquire blood flow data first, analyzed and arranged, output ripple frequency and signal
Amplitude instruction, converts by DA data analog signal, dependent instruction is transmitted in peristaltic pump 2, controls artificial in liquid reserve tank 4
Blood is transported in arteries model 5 by connecting tube 3, and under the action of pressure regulator 6, artificial blood passes through venous blood
Tube model 7 flows back to liquid reserve tank 4；
S2, artificial blood circulation during, people by pressure sacculus 13 import bracket, in 11 He of pressure sensor
Under the action of high frequency camera shooting machine 10, realize detection lesion vessels model 9 in pressure value variation and bracket transport, be implanted into, expanding,
Support process shows pressure waveform image and support motion image on computer 1.
Above-described specific embodiment has carried out further the purpose of the present invention, technical scheme and beneficial effects
It is described in detail, it should be understood that being not limited to this hair the foregoing is merely a specific embodiment of the invention
Bright, all within the spirits and principles of the present invention, any modification, equivalent substitution, improvement and etc. done should be included in the present invention
Protection scope within.
Claims (5)
1. a kind of biomechanics experiment simulator of endovascular stent implantation, including computer (1), peristaltic pump (2), connecting tube
(3), liquid reserve tank (4), arteries model (5), pressure regulator (6) and vein blood vessel model (7), it is characterised in that:
The peristaltic pump (2) is connected with connecting tube (3), and one end of the connecting tube (3) is connected with liquid reserve tank (4), described
The other end of connecting tube (3) is connected with arteries model (5), and the other end of the arteries model (5) passes through pressure
Adjuster (6) is connected with one end of vein blood vessel model (7), the other end of the vein blood vessel model (7) and liquid reserve tank (4)
Upper surface be connected；
The arteries model (5) includes two branch vessel models (8), and is respectively provided in two branch vessel models (8)
Have lesion vascular pattern (9), and is provided with high frequency camera shooting machine (10) on one of lesion vessels model (9), and be provided with height
It is connected respectively with two pressure sensors (11) at left and right sides of the lesion vessels model (9) of frequency video camera (10), and another
The right side of lesion vessels model (9) is connected with pressure sensor (11), and the quantity of pressure sensor (11) is three, and position
It is connected in the right side of one of lesion vessels model (9) with the one end for establishing tube channel (12), it is described to establish tube channel
(12) the other end is connected with interface (13) are punctured；
It is provided with flowmeter (14) in the arteries model (5), the flowmeter (14) is located at branch vessel model (8)
Right side, and flowmeter (14) adopts the data of arteries model (5) interior blood flow, by signal imitation comparative analysis, display
Artificial blood flow waveform figure out；
The computer (1) is analyzed and is arranged by acquisition blood flow data, output ripple frequency, signal amplitude
Instruction is converted by DA data analog signal, and dependent instruction is transmitted in peristaltic pump (2), controls blood flow, and three pressures
Force snesor (11) acquires the data of two interior pressure changes of lesion vessels model (9), by comparing and analyzing between each other, shows
Pressure waveform figure is shown；
High frequency camera shooting machine (10) the captured in real-time lesion vessels inner support transports, is implanted into, expanding, support process, by image
Processing module processing and parsing, show the image of support motion.
2. a kind of biomechanics experiment simulator of endovascular stent implantation according to claim 1, it is characterised in that:
The material of the lesion vessels model (9) is transparent silicone rubber, the long 12-15cm of blood vessel, wall thickness 2.4-3.7mm, entrance and exit
Section interior diameter is 3-6cm.
3. a kind of biomechanics experiment simulator of endovascular stent implantation according to claim 1, it is characterised in that:
Artificial blood is stored in the liquid reserve tank (4), artificial blood is the artificial synthesized fluorocarbons with function of carrying oxygen, fluorine carbon
For the colloid submicron emulsion that blood is made of perfluorochemical, there is good oxygen carrying capacity, in a certain concentration and partial pressure of oxygen
Under the conditions of, oxygen solubility is 20 times of water, 2 times higher than blood.
4. a kind of biomechanics experiment simulator of endovascular stent implantation according to claim 1, it is characterised in that:
The bracket generates plastic deformation in pressure air bag inflating pressure, and after pressure air bag is deflated, bracket still keeps expansion state, and
The material of bracket should have low yield stress and high elastic modulus, so that after pressure air bag is inflated, rack elasticity retraction is small.
5. a kind of biomechanics experiment simulator of endovascular stent implantation according to claim 1, it is characterised in that:
The pressure regulator (6) adjusts the pressure of blood between arteries model (5) and vein blood vessel model (7).
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| CN201910777487.7A CN110491231A (en) | 2019-08-22 | 2019-08-22 | A kind of biomechanics experiment simulator of endovascular stent implantation |
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| CN201910777487.7A CN110491231A (en) | 2019-08-22 | 2019-08-22 | A kind of biomechanics experiment simulator of endovascular stent implantation |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111024909A (en) * | 2019-12-12 | 2020-04-17 | 西安医学院 | Thrombolysis medicine detection device |
| CN111141485A (en) * | 2020-01-10 | 2020-05-12 | 中国人民解放军总医院第六医学中心 | Intervention operation simulation device for covered stent of abdominal aortic aneurysm |
| CN113160678A (en) * | 2021-04-28 | 2021-07-23 | 昆明理工大学 | Blood circulation analogue means for pathology experiments |
| CN113503907A (en) * | 2021-08-11 | 2021-10-15 | 清华大学 | In-vitro circulation experiment table and experiment method for medical implant intervention body observation |
| CN113503906A (en) * | 2021-08-11 | 2021-10-15 | 清华大学 | In-vitro circulation experiment table and method for medical implant intervention body thrombosis |
| CN113654773A (en) * | 2021-06-30 | 2021-11-16 | 北京航空航天大学 | Near-physiological pulsating flow loading device for fatigue test of intravascular stent |
| CN116758806A (en) * | 2023-08-18 | 2023-09-15 | 首都医科大学附属北京天坛医院 | Intravascular stent external simulation device |
| CN117269284A (en) * | 2023-11-22 | 2023-12-22 | 中国人民解放军军事科学院军事医学研究院 | Oxygen carrying-releasing capacity relative evaluation device |
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| CN113503906B (en) * | 2021-08-11 | 2022-12-20 | 清华大学 | In-vitro circulation experiment table and method for medical implant intervention body thrombosis |
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