CN108053708A - A kind of Dynamic Pulse emulation module - Google Patents
A kind of Dynamic Pulse emulation module Download PDFInfo
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Abstract
A kind of Dynamic Pulse emulation module, it is related to medical teaching field, including collection apparatus module, vital sign analog module, dynamic simulation module, display module, pulse wave data is from clinic, pass through collection apparatus module, can the pulse data of clinical different pathologic conditions be subjected to collection apparatus and obtain the pulse wave characteristic of different cases, when medico is trained operation, the variation of vital sign analog module real-time Simulation physiological parameter, pass data to dynamic simulation module, corresponding dynamic is carried out to pulse wave in real time to adjust, realize the dynamic analog of pulse wave, and pass through display module and carry out output and show.
Description
Technical field
The present invention relates to medical teaching field more particularly to a kind of dynamic pulse wave emulation modules.
Background technology
Pulse, that is, arteriopalmus, pulse frequency, that is, pulse frequency, normal person's pulse frequency rule, is not in pulse interval time length
The phenomenon that differing, the pulse wave of human body can be recorded with special sphygmometer, and each pulse tracing curve is by rising
Branch A and descending branch K is formed.The passive expansion of artery, descending branch reflect the retraction for penetrating the blood later stage in the ascending branch reflection fast rapid fire blood of ventricle.With
Ventricular diastole afterwards, intraventricular pressure are less than aortic blood pressure, and then arterial blood is flow backwards, and causes aortic valve closing, the shape on curve
Into descending branch incisura N, dicrotic notch or weight trough are also since the closing of aorta petal makes the blood of refluence continue to flow away forward then, and
Occur the small echo risen again after incisura, claim dicrotic wave or dicrotic wave.The shape of descending branch is related with the size of peripheral resistance；Such as
Then the descending branch gradient is relatively slow greatly for resistance, and the position of incisura is higher；Conversely, the position of incisura is relatively low.
Clinically there are many disease, particularly heart disease can make pulse change, therefore measure pulse for patient
It is an indispensable inspection item, the variation of pulse and doctor are to the one of which foundation of diagnosing patient, pulse signal
Form, slight, rate, the rhythm and pace of moving things can reflect many physiology and pathological characters of cardiovascular system of human body, the shape of pulse wave
Shape, different due to the situation change of the circulatory system, if whether aorta petal perfects, whether the rhythm of heart is normal, the bullet of arterial
Property as how, can all be diagnosed, in first aid procedures, especially be lost blood, heartbeat is overrun, heartbeat according to the variation of pulse wave
When the situations such as all standing and CPR operation, cardiovascular system of human body changes greatly, comparatively fast, and the diagnosis of pulse wave exists
Extremely important effect is played in first aid procedures.
Acquisition pulse true pulse signal difficulty is big under emergency situations, and clinical data is few, in first aid simulated training, human body
The variation of pulse signal embodies the important information of person's physiological processes, and in existing first aid analog equipment, emulate the signal of pulse
All it is only fixed form, speed adjust can only be carried out, it is impossible to react human body physiology course information jumpy, it is impossible to for doctor
Shield personnel provide the dynamic analog of pulse wave under emergency situations, if Shanghai Univ. of Traditional Chinese Medicine is according to designing the formation basic theory of pulse
Chinese medicine pulse simulation system can generate 16 kinds of different pulse conditions, University Of Tianjin and the arteries and veins of Tianjin University Of Traditional Chinese Medicine's joint research and development altogether
As examination apparatus, the traditional Chinese medical science all 28 kinds of pulse conditions can be simulated.
The content of the invention
In order to realize the emulation of a variety of case pulse waves, the present invention provides it is a kind of it is easy to operate, can in first aid training
With the pulse emulation module of real time dynamic simulation.
The technical solution adopted in the present invention is：A kind of Dynamic Pulse emulation module, including：Collection apparatus module is used
In obtaining clinical pulse wave, initial emulation pulse wave is generated, and extracts the characteristic parameter of initial emulation pulse waveform；Life entity
Analog module is levied, the clinical pulse wave based on foregoing acquisition carries out the simulation of vital sign；Dynamic simulation module, for obtaining
The vital sign data of vital sign analog module is stated, judges the type of vital sign physiological parameter data variation, and to described
The characteristic parameter of initial emulation pulse waveform is adjusted, and generates dynamic emulation pulse wave；Display module, for exporting just
Beginning emulation pulse involves dynamic emulation pulse wave.
The specific steps of the collection apparatus module include：
1) clinical pulse wave data is obtained：Clinical pulse data is arteries and veins figure：Described point is carried out to arteries and veins figure, extracts pulse wave
Coordinate value carries out coordinate value with linear interpolation method abscissa homogenization linear interpolation processing, and then obtains uniform sampling
Pulse wave data；Clinical pulse data is electric signal：Pulse wave data is obtained by Sensor monitoring；
2) pulse wave is rebuild：It is superimposed using Gaussian function as basic function, expression formula is：；
Using least square fitting, calculate the parameter of three Gaussian functions, respectively with V, T and U come represent the amplitude of Gaussian function,
It is expected and variance, obtain 9 parameters, i.e. V1, V2, V3, T1, T2, T3, U1, U2, U3；
3) characteristic parameter is extracted：F1, F2, F3, F1=V3/V1 characterization peripheral resistances；F2=T3-T1 characterizes arterial compliance；F3
=U1 is main wave width parameter.
The vital sign analog module includes at least ECG Simulation data module, blood pressure data module, oximetry data mould
Block, breathing emulation data module, temperature data mould one kind in the block.
The dynamic simulation module includes：
Vital sign acquiring unit for obtaining the vital sign data of foregoing vital sign analog module simulation, judges life
The type that physiological parameter changes in sign data；
Dynamic analog unit, for the type of the physiological parameter variation obtained according to vital sign acquiring unit, adjustment feature ginseng
Number generates dynamic emulation pulse wave.
The characteristic parameter adjustment mode includes at least one kind in the following manner：
1）Changes in heart rate：Pulse wave amplitude VHR=AHR*V；AHR=1-（HR-M）* K, wherein：Heart rate is in normal range (NR)（60-100
Beat/min）Interior, F1, F2, F3 parameter are all constant, and single pulse wave form does not change, and are folded between adjusting pulse wave by dynamic
Length is closed, simulates pulse wave during heart rate dynamic change；When heart rate is higher than 100 beats/min, M=100, K=0.008；Heart rate is less than 60
Beat/min when, M=60, K=0.003；
2）Blood pressure：During blood pressure, pulse wave amplitude wave-shape changes, using mean arterial pressure as reference, Mean Arterial
Pressure often rises or falls 10mmHg, and the amplitude for emulating the main ripple of pulse wave, dicrotic wave and dicrotic pulse prewave accordingly increases or decreases
10%.When blood pressure raises, the spacing between dicrotic wave, dicrotic pulse prewave and main ripple shortens, when blood pressure declines, dicrotic wave, dicrotic pulse prewave
Spacing between main ripple is elongated, and mean arterial pressure often rises or falls 10mmHg, and F2 adjusts 3% downward or upward；
3）Ventricular fibrillation：Generation room is quivered situation, and effective heartbeat stops, with whole body after the faint vibration wave simulation heart arrest of amplitude
The state of blood pressure regional balance in vivo.
The beneficial effects of the invention are as follows：A kind of pulse wave data of Dynamic Pulse emulation module passes through from clinic
Collection apparatus module, can be by the initial emulation pulse wave of pulse data generation of clinical different pathologic conditions, and carries out feature and adopt
Collection obtains the pulse wave characteristic parameters of different cases, and the life of vital sign analog module simulation is obtained by dynamic simulation module
Sign data is analyzed, and is judged the mode of physiological parameter variation, is selected corresponding pulse wave characteristic parameters adjustment mode, into
And dynamic emulation pulse wave is generated, and output is carried out by display module and is shown, medico in operation, can be by showing mould
Block sees the emulation pulse wave of patient's original state, can be with by the analysis to illness and the diagnosis and treatment process applied to patient
The vital sign data generated by vital sign analog module is obtained, then vital sign data is carried out via dynamic simulation module
Analyzing and processing judges the variation pattern of vital sign data physiological parameter, selects the adjustment side of corresponding pulse wave characteristic parameters
Formula, and then dynamic emulation pulse wave is generated, and display is exported, realize the dynamic analog of pulse wave.
Description of the drawings
Fig. 1 is a kind of work flow diagram of Dynamic Pulse emulation module of the present invention；
Fig. 2 is the pulse waveform figure under hemorrhagic shock patient's different conditions of the embodiment of the present invention.
Specific embodiment
As shown in Figure 1, a kind of overall workflow of Dynamic Pulse emulation module includes：
1. the initial emulation pulse wave of generation, extracts characteristic parameter：
1）Obtain pulse wave data：Clinical pulse data is arteries and veins figure：Described point is carried out to arteries and veins figure, extracts the coordinate of pulse wave
Value carries out coordinate value with linear interpolation method abscissa homogenization linear interpolation processing, and then obtains the pulse of uniform sampling
Wave number evidence；Clinical pulse data is electric signal：Pulse wave data is obtained by Sensor monitoring；
2）Rebuild pulse wave：Pulse wave may be considered to be formed by stacking by main ripple, dicrotic wave and dicrotic pulse prewave, by pulse wave
Each characteristic wave is with a Gaussian function come approximate, then each pulse wave is rebuild by three Gaussian functions, by formulaIt represents；Using least square fitting, the parameter of three Gaussian functions is calculated, respectively with V, T
Represent the amplitude of Gaussian function, expectation and variance with U, obtain 9 parameters, i.e. V1, V2, V3, T1, T2, T3, U1,
U2, U3 generate initial emulation pulse wave；
3）Extract characteristic parameter：F1, F2, F3, F1=V3/V1 characterization peripheral resistances；F2=T3-T1 characterizes arterial compliance；F3=
U1 is main wave width parameter；
2. vital sign is simulated：Based on foregoing clinical pulse wave data, initial physiological parameter is generated, and passes through ECG Simulation number
Vital sign is carried out according to module, blood pressure data module, oximetry data module, breathing emulation data module, temperature data module
Simulation, the data of aforementioned modules can be calculated by what physiology drove;It can also be by link model people, to model person
After carrying out treatment operation, vital sign data is generated；
3. dynamic simulation：Including vital sign acquiring unit, dynamic analog unit, specific steps include：
1）Obtain vital sign data：Vital sign acquiring unit obtains above-mentioned vital sign and simulates vital sign life in each module
The data of parameter are managed, judge the type of physiological parameter variation；
2）Adjust characteristic parameter：Data of the dynamic analog unit according to physiological parameter variation, select corresponding adjustment mode, wrap
It includes：
(1) changes in heart rate：Pulse wave amplitude VHR=AHR*V；AHR=1-（HR-M）* K, wherein：Heart rate is in normal range (NR)（60-100
Beat/min）Interior, F1, F2, F3 parameter are all constant, and single pulse wave form does not change, and are folded between adjusting pulse wave by dynamic
Length is closed, simulates pulse wave during heart rate dynamic change；When heart rate is higher than 100 beats/min, M=100, K=0.008；Heart rate is less than 60
Beat/min when, M=60, K=0.003；
(2) blood pressure：During blood pressure, pulse wave amplitude wave-shape changes, using mean arterial pressure as reference, Mean Arterial
Pressure often rises or falls 10mmHg, and the amplitude for emulating the main ripple of pulse wave, dicrotic wave and dicrotic pulse prewave accordingly increases or decreases
10%.When blood pressure raises, the spacing between dicrotic wave, dicrotic pulse prewave and main ripple shortens, when blood pressure declines, dicrotic wave, dicrotic pulse prewave
Spacing between main ripple is elongated, and mean arterial pressure often rises or falls 10mmHg, and F2 adjusts 3% downward or upward；
(3) ventricular fibrillation：Generation room is quivered situation, and effective heartbeat stops, with complete after the faint vibration wave simulation heart arrest of amplitude
The state of body blood pressure regional balance in vivo；
3）Rebuild pulse wave：Characteristic parameter after adjustment carries out Gaussian function reconstruction, generates dynamic emulation pulse wave.
4. output display：The initial emulation pulse of display involves dynamic emulation pulse wave.
The present invention is further explained by taking the dynamic simulation of hemorrhagic shock patient's pulse as an example below：
1）Patients clinical arteries and veins figure is obtained as shown in a in Fig. 2, described point is carried out to the arteries and veins figure, the coordinate value of pulse wave is extracted, uses line
Property interpolation method abscissa homogenization linear interpolation processing is carried out to coordinate value, and then obtain the pulse wave data of uniform sampling；
2）It is rebuild using three Gaussian functions, by formulaIt represents；Intended using least square method
It closes, calculates the parameter of three Gaussian functions, represent the amplitude of Gaussian function, expectation and variance with V, T and U respectively, obtain 9
A parameter, i.e. V1, V2, V3, T1, T2, T3, U1, U2, U3 obtain initially emulating pulse wave as shown in b in Fig. 2, and
It is exported and shown by display module；
3）Defined feature parameter：F1=V3/V1 characterizes peripheral resistance；F2=T3-T1 characterizes arterial compliance；F3=U1 is main ripple
Width parameter；
4）Initial vital sign, based on clinical arteries and veins figure, initial physiological parameter is as shown in the table；
| Name | Gender | Age | Weight (kg) | Height (cm) | Heart rate | Fatty fraction | Systolic pressure | Diastolic pressure | Respiratory rate |
| LY | Man | 40 | 72.5 | 173 | 72 | 0.25 | 114 | 73.5 | 18 |
5）Vital sign is simulated：Patient trauma acute bleeding, blood volume reduce, and cause tachycardia, and heart rate compensatory rises, blood
Drops；
6）Vital sign data in vital sign acquiring unit obtaining step 5 judges that heart rate and blood pressure change, dynamic analog
Quasi-simple member selects adjustment pulse wave characteristic parameters when heart rate, blood pressure to be adjusted according to the variation, and generates bleeding initial stage
Emulation pulse wave, as shown in c in Fig. 2, and by display module export show；
7）Vital sign is simulated：Hypovolemic shock occurs for patient, then heart arrest, and room occurs and quivers；
8）Vital sign data in vital sign acquiring unit obtaining step 7 judges that room, which occurs, quivers situation, dynamic analog unit
Pulse wave characteristic parameters are adjusted when quivering according to room to be adjusted, and the emulation pulse wave when room of generation is quivered, as shown in d in Fig. 2, and
It is exported and shown by display module；
9）Vital sign is simulated：Stopped blooding to patient, fluid infusion, dosing techniques, carry out defibrillation procedure, patient's heartbeating recovery, arteries and veins
It fights recovery；
Vital sign data in 10 vital sign analogue unit obtaining steps 9, judges that heart rate, blood pressure gradually recover, dynamic analog
Quasi-simple member is adjusted pulse wave characteristic parameters, and generates the emulation pulse wave of initial stage recovery after treatment, as shown in e in Fig. 2,
And it is exported and shown by display module；
11 vital signs are simulated：Patient's blood pressure rises, and recovers normal；
Vital sign data in 12 vital sign analogue unit obtaining steps 11 judges that heart rate, blood pressure recover normal, dynamic analog
Quasi-simple member is adjusted pulse wave characteristic parameters, and generates the emulation pulse wave after recovering, as shown in b in Fig. 2, and by showing
Module output display.
Patient's original state is only listed in above step, bleeding initial stage, room are quivered, treatment initial stage and when recovering normal condition
Vital sign simulation and the dynamic emulation pulse wave that generates of when corresponding states, emulated in a kind of Dynamic Pulse of the present invention
In module, vital sign simulation is real-time with dynamic emulation pulse wave, i.e. vital sign acquiring unit obtains life in real time
Vital sign data in sign analog module, dynamic analog unit carry out real-time data point reuse, and generation is dynamic in real time
Emulate pulse wave.
Claims (4)
1. a kind of Dynamic Pulse emulation module, which is characterized in that including：
Collection apparatus module for obtaining clinical pulse wave, generates initial emulation pulse wave, and extracts initial emulation pulse wave ripple
The characteristic parameter of shape；
Vital sign analog module, the clinical pulse wave based on foregoing acquisition carry out the simulation of vital sign；
Dynamic simulation module for obtaining the vital sign data of the vital sign analog module, judges vital sign physiology
The type of supplemental characteristic variation, and the characteristic parameter of the initial emulation pulse waveform is adjusted, it generates dynamic imitative
True pulse wave；
Display module involves dynamic emulation pulse wave for exporting initial emulation pulse.
2. a kind of Dynamic Pulse emulation module according to claim 1, which is characterized in that the collection apparatus module
Specific steps include：
1) clinical pulse wave data is obtained；
2) pulse wave is rebuild：It is superimposed using Gaussian function as basic function, expression formula is：；It adopts
With least square fitting, the parameter of three Gaussian functions is calculated, represents the amplitude of Gaussian function, phase with V, T and U respectively
Prestige and variance, obtain 9 parameters, i.e. V1, V2, V3, T1, T2, T3, U1, U2, U3；
3) characteristic parameter is extracted：F1, F2, F3, F1=V3/V1 characterization peripheral resistances；F2=T3-T1 characterizes arterial compliance；F3
=U1 is main wave width parameter.
3. a kind of Dynamic Pulse emulation module according to claim 1, which is characterized in that the vital sign simulates mould
Block includes at least ECG Simulation data module, blood pressure data module, oximetry data module, breathing emulation data module, body temperature number
According to mould one kind in the block.
A kind of 4. Dynamic Pulse emulation module according to claim 1, which is characterized in that the dynamic simulation module bag
It includes：
Vital sign acquiring unit for obtaining the vital sign data of foregoing vital sign analog module simulation, judges life
The type that physiological parameter changes in sign data；
Dynamic analog unit, for the type of the physiological parameter variation obtained according to vital sign acquiring unit, adjustment feature ginseng
Number generates dynamic emulation pulse wave.
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| CN109998529A (en) * | 2019-04-15 | 2019-07-12 | 北京工业大学 | P wave, T wave detecting method in a kind of ECG signal based on Gaussian function fitting |
| CN110444072A (en) * | 2019-08-06 | 2019-11-12 | 成都泰盟软件有限公司 | A kind of entity and virtual physiological test real time fusion system |
| CN110811572A (en) * | 2019-10-18 | 2020-02-21 | 西安交通大学 | Simulation synthesis method and device for photoelectric volume wave signal |
| CN111685749A (en) * | 2020-06-18 | 2020-09-22 | 郑昕 | Construction method of pulse pressure wave mathematical model |
| CN114259206A (en) * | 2021-12-02 | 2022-04-01 | 萤雪科技(佛山)有限公司 | Pulse wave fitting method, system, computer equipment and readable storage medium |
| CN118587960A (en) * | 2024-08-06 | 2024-09-03 | 嘉兴元贝贝科技有限公司 | Device and system for simulating heartbeat and breathing of human body by electromagnetic force |
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| CN114259206A (en) * | 2021-12-02 | 2022-04-01 | 萤雪科技(佛山)有限公司 | Pulse wave fitting method, system, computer equipment and readable storage medium |
| CN114259206B (en) * | 2021-12-02 | 2024-03-29 | 萤雪科技(佛山)有限公司 | Pulse wave fitting method, system, computer device and readable storage medium |
| CN118587960A (en) * | 2024-08-06 | 2024-09-03 | 嘉兴元贝贝科技有限公司 | Device and system for simulating heartbeat and breathing of human body by electromagnetic force |
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