CN110464781A - A kind of external application Chinese medicine and preparation method thereof for treating tonsillitis and abscess of throat - Google Patents
A kind of external application Chinese medicine and preparation method thereof for treating tonsillitis and abscess of throat Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract
The embodiment of the invention discloses a kind of external application Chinese medicine and preparation method thereof for treating tonsillitis and abscess of throat, 20 parts by weight of blackberry lily that will be made, 20 parts by weight of subprostrate sophora, 10 parts by weight of myrrh, 10 parts by weight of Lasiosphaera fenzlii, 10 parts by weight of Radix Glycyrrhizae, which are mixed, is ground into powder, collects spare；It separately takes 5 parts by weight of blackberry lily piece, 5 parts by weight of subprostrate sophora, 5 parts by weight of myrrh, 5 parts by weight of Radix Glycyrrhizae, 5 parts by weight of Lasiosphaera fenzlii that sesame oil is added, is heated after impregnating 24 hours, filter out attachment, crush；It is stirred in the oily decoction for taking 6 parts by weight of colophony powder investment to be squeezed, oily medicine rosin stream cream is made, the raw material medicinal powder of above-mentioned all crushing is merged, oily medicine rosin stream cream is added, it stirs well into medicine puree addition matrix and Silica hydrogel paste is made, the present invention solve oral traditional Chinese medicine in the prior art it is fried it is cumbersome, side effect is big when taking and the technical issues of being also easy to produce adverse reaction, be widely used in controlling outside tonsillitis and abscess of throat.
Description
Technical field
The present embodiments relate to Chinese medicine external technical fields, and in particular to a kind of to treat the outer of tonsillitis and abscess of throat
With Chinese medicine and preparation method thereof.
Background technique
In China, tonsillitis, abscess of throat are a kind of very high diseases of disease incidence, with the improvement of living standards and are drunk
The change of dietary habits, recent years, the disease incidence of tonsillitis was in that raised trend, every 10 people about just have 6-7 year by year always
Suffered from tonsillitis or abscess of throat, although tonsillitis is controlled well, easily repeatedly, the above year is universal and extensive due to Western medicine
Using most of patients selects based on western medicine, and some patients due to recurring enlargement repeatedly, so that excision.It is western as you know
Medicine is palliative, and prolonged application antibiotic, and many Pseudomonas is caused to develop drug resistance.Removal of tonsils is expedient
Meter, be a kind of harmful method without benefit.Due to the defect for the treatment of method, the patient of most of chronic tonsillitis is formd, and
It is again and again not easy to cure, keeps patient very painful, seriously affect quality of life.There are some patientss due to more not concurrent for a long time
Ephritis etc..
In Chinese medicine, tonsillitis is treated at present, abscess of throat mostly uses oral traditional Chinese medicine, it is well known that oral traditional Chinese medicine is decocted
It is bothersome laborious to take process, it is also necessary to grasp step of correctly boiling medicine, relatively high, and oral traditional Chinese medicine taste is required for user
Hardship, need to be through gastrointestinal absorption, and Chinese medicine stimulates caused by gastrointestinal mucosa and damage larger, and it is bad anti-that many patients will appear vomiting etc.
It answers.
Therefore, in Chinese medicine external technical field, for a kind of external application Chinese medicine for treating tonsillitis and abscess of throat and its
For preparation method there are still research and improved demand, this is also a research hotspot in current Chinese medicine external technical field and again
The starting point that point, the even more present invention are accomplished.
Summary of the invention
For this purpose, the embodiment of the present invention provides a kind of external application Chinese medicine for treating tonsillitis and abscess of throat, to solve existing skill
In art oral traditional Chinese medicine it is fried it is cumbersome, side effect is big when taking and the technical issues of being also easy to produce adverse reaction.
To achieve the goals above, the embodiment of the present invention provides the following technical solutions:
A kind of external application Chinese medicine for treating tonsillitis and abscess of throat, including following components: blackberry lily 20-30 parts by weight, mountain beans
Root 20-30 parts by weight, myrrh 10-20 parts by weight, Lasiosphaera fenzlii 10-20 parts by weight, Radix Glycyrrhizae 10-20 parts by weight.
The embodiment of the present invention also provides a kind of preparation method of external application Chinese medicine for treating tonsillitis and abscess of throat, including with
Lower step:
S1, blackberry lily 15-25 parts by weight and subprostrate sophora 15-25 parts by weight are taken, while put into stainless-steel pan, use acetate concentration
It is stirred well for 6 degree of acetum 1.2-1.8 parts by weight spray-stain, after lid pot bored 3 hours, small fire heating, frying to micro- has macula lutea taking-up
It dries spare；
S2, it takes in myrrh 5-15 parts by weight investment stainless-steel pan, mild fire heating, fries to the surface that smolders is micro- and melt, cease fire micro- cool
Afterwards, the acetum 0.4-1.1 parts by weight spray-stain for being 6 degree with acetate concentration stirs well reheating and fries to the glossy taking-up in surface and dries
It is spare；
S3, it takes in sheet Lasiosphaera fenzlii 5-15 parts by weight investment stainless-steel pan, the honey juice 0.5-1 parts by weight for being 60% with concentration
Lasiosphaera fenzlii in spray-stain pot, stirs well, and the micro- stir-fry taking-up of small fire heating is dried spare；
S4, it takes in sheet Radix Glycyrrhizae 5-15 parts by weight investment stainless-steel pan, the honey juice 0.5-1 parts by weight for being 60% with concentration
Lasiosphaera fenzlii in spray-stain pot, stirs well, small fire heating, fries to there is Cauterize spot, taking-up is dried spare；
S5, the blackberry lily 15-25 parts by weight that will be made, subprostrate sophora 15-25 parts by weight, myrrh 5-15 parts by weight, Lasiosphaera fenzlii 5-15
Parts by weight, Radix Glycyrrhizae 5-15 parts by weight are mixed in investment wall-breaking machine and are ground into 300 mesh powders, collect spare；
S6,5 parts by weight of blackberry lily piece, 5 parts by weight of subprostrate sophora, 5 parts by weight of myrrh, 5 parts by weight of Radix Glycyrrhizae, 5 weight of Lasiosphaera fenzlii are separately taken
In part investment stainless-steel pan, sesame oil is added, is heated to 180-200 degree after impregnating 24 hours, and stirs, fries to bulk pharmaceutical chemicals and be with Cauterize
Degree filters out dregs of a decoction investment filter core machine and gets rid of net sesame oil attachment, it is spare to be ground into 300 mesh fine powders；
S7, it takes in the oily decoction that is squeezed of 6 parts by weight of colophony powder investment and stirs, be heated to 60 degree and be completely melt to colophony powder
Oily medicine rosin stream cream is made in filtering afterwards, spare；
S8, the raw material medicinal powder of above-mentioned all crushing is merged, puts into stainless steel cauldron and stirs evenly, oily medicine rosin is added
Cream is flowed, it is spare to stir well into medicine puree；
S9, above-mentioned medicine puree is added in matrix, Silica hydrogel paste is made.
Further, the matrix includes following components:
Medical use liquid silicon coagulates 12.7 parts by weight of gel,
0.8 parts by weight of carmethose,
6 parts by weight of colophony powder,
0.5 parts by weight of lanolin,
1.5 parts by weight of azone,
2 parts by weight of borneol.
Further, the making step of the matrix is as follows:
12.7 part by weight of liquid Silica hydrogels are put into stainless-steel pan, with 0.3 parts by weight of ethanol by carmethose 0.8
Parts by weight, 0.5 parts by weight of lanolin dissolve by heating, and are then added in stainless-steel pan, add 1.5 parts by weight azones, 2 weights are added
Amount part borneol powder stir evenly the matrix.
Further, the matrix for being mixed with medicine puree is stirred evenly, pinches into ointment, remove the ointment investment stainless steel cooked flake wrapping machine
In, be pressed into 1.5mm thickness cream cake, cream cake be cut into 3.5cm × 3.5cm circle lotion, then by round lotion it is viscous be pressed in it is medical
On spun laced fabric, anti-sticking oilpaper in lotion face pressure is cut into edge greater than lotion 6cm × 4.5cm ellipse backing, and then pack is sealed
Mouthful, finished product silica gel paste is made.
Further, in step s 6, sesame oil lid crosses bulk pharmaceutical chemicals.
Further, the oily medicine weight ratio of sesame oil and bulk pharmaceutical chemicals is 5:3.
The embodiment of the present invention has the advantages that
(1) the formula of the invention is reasonable, curative for effect, and application time is short, and take effect fast victory, the present invention from a large amount of clearing heat, relieving sore-throats,
It is screened in swelling and pain relieving class recipe, finally constitutes and constituted by blackberry lily, subprostrate sophora, myrrh, Lasiosphaera fenzlii, Radix Glycyrrhizae traditional Chinese medicine of the five flavours
Prescription, and pass through a large amount of clinical verification, the results showed that the prescription has effects that detoxification detumescence, promoting blood circulation and stopping pain, clearing heat, relieving sore-throat,
And other medicines relatively are more targeted, can be used as the external curing medicine of tonsillitis, abscess of throat.
(2) present invention uses interior disease outer treating method, compared with existing oral medication tonsillitis, abscess of throat drug, both
There is the accuracy of target administration, not only increase curative effect reduces side effect again, while also improving the compliance of medication.
(3) present invention is integrated with the traditional handicrafts such as the various processing methods to different material medicine, frying, broken wall and the modern times are advanced
New pharmaceutical technology combine, both improved the utilization rate of raw material pharmaceutically active ingredient, be sufficiently enriched the performance of effective component, institute
Chinese medicinal ointment obtained comply fully with " three is small " (prescription small, small toxicity, Small side effects) " two effects one are short " (it is efficient, quick-acting, stick
Time is short) " five convenience " (easy to use, easy to carry, convenient for production, convenient transportation, the convenient modern pharmaceutical direction of storage).
(4) present invention by blackberry lily, subprostrate sophora, myrrh, Lasiosphaera fenzlii, Radix Glycyrrhizae, separately process and processing, with other conventional decoctings,
Alcohol extracting, compared to gained active component content it is higher, curative effect is better.
(5) present invention realizes Chinese medicine external, fried good Chinese medicine is arranged on medical spun laced fabric, direct cave when needing
Position sticks uses, not stimulating intestine and stomach, solve oral traditional Chinese medicine in the prior art it is fried it is cumbersome, side effect greatly and is also easy to produce when taking
The technical issues of adverse reaction.
Specific embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this explanation
Content disclosed by book is understood other advantages and efficacy of the present invention easily, it is clear that described embodiment is the present invention one
Section Example, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not doing
Every other embodiment obtained under the premise of creative work out, shall fall within the protection scope of the present invention.
Embodiment one:
The embodiment of the invention provides a kind of external application Chinese medicines for treating tonsillitis and abscess of throat, including following components: penetrating
Dry 20 parts by weight, 20 parts by weight of subprostrate sophora, 10 parts by weight of myrrh, 10 parts by weight of Lasiosphaera fenzlii, 10 parts by weight of Radix Glycyrrhizae.
Embodiment two:
The embodiment of the invention provides a kind of external application Chinese medicines for treating tonsillitis and abscess of throat, including following components: packet
Include following components: 25 parts by weight of blackberry lily, 25 parts by weight of subprostrate sophora, 15 parts by weight of myrrh, 15 parts by weight of Lasiosphaera fenzlii, 15 weight of Radix Glycyrrhizae
Part.
Embodiment three:
The embodiment of the invention provides a kind of external application Chinese medicines for treating tonsillitis and abscess of throat, including following components: packet
Include following components: 30 parts by weight of blackberry lily, 30 parts by weight of subprostrate sophora, 20 parts by weight of myrrh, 20 parts by weight of Lasiosphaera fenzlii, 20 weight of Radix Glycyrrhizae
Part.
The treatment tonsillitis and the external application Chinese medicine of abscess of throat use pure Chinese medicinal preparation, with strong points, existing target administration
Accuracy, not only increase curative effect reduces side effect again, while also improving the compliance of medication.
Example IV:
The embodiment of the present invention also provides a kind of preparation method of external application Chinese medicine for treating tonsillitis and abscess of throat, including with
Lower step:
S1,15 parts by weight of 15 parts by weight of blackberry lily and subprostrate sophora are taken, while put into stainless-steel pan, be 6 degree with acetate concentration
1.2 parts by weight spray-stain of acetum stir well, here, with the Shanxi mature vinegar better effect of 6 degree of pure brewings, lid pot bored 3 hours
Afterwards, small fire heats, and fries to micro- that have macula lutea taking-up to dry spare, and processing above Chinese medicine with acetic acid is to reduce a part of bulk pharmaceutical chemicals
Toxic side effect and change its raw medicine, be conducive to clinical safety and use and improve curative effect；
S2, take in 5 parts by weight of myrrh investment stainless-steel pan, mild fire heating, fry it is micro- molten to the surface that smolders, cease fire it is micro- it is cool after,
The 0.4 parts by weight spray-stain of acetum for being 6 degree with acetate concentration stirs well reheating and fries to the glossy taking-up in surface and dries spare, use
It is to be conducive to clinical safety to reduce the toxic side effect of a part of bulk pharmaceutical chemicals and change its raw medicine that acetic acid, which processes the above Chinese medicine,
Use and improve curative effect；
S3, it takes in 5 parts by weight of sheet Lasiosphaera fenzlii investment stainless-steel pan, the 0.5 parts by weight spray-stain of honey juice for being 60% with concentration
Lasiosphaera fenzlii in pot, stirs well, small fire heat micro- stir-frys taking-up dry it is spare, here, honey juice concentration is weight concentration, 60% honey juice,
Honey containing 300g, 200g pure water in i.e. every 500g honey juice, heating stirs well to obtain the final product after mixing, processes the above Chinese medicine with honey juice
It is to be conducive to clinical safety in order to reduce the toxic side effect of a part of bulk pharmaceutical chemicals and change its raw medicine and use and improve curative effect；
S4, it takes in 5 parts by weight of sheet Radix Glycyrrhizae investment stainless-steel pan, the 0.5 parts by weight spray-stain of honey juice for being 60% with concentration
Lasiosphaera fenzlii in pot, stirs well, small fire heating, fries to there is a Cauterize spot, taking-up dry it is spare, here, honey juice concentration is weight concentration, 60%
Honey juice, i.e., honey containing 300g, 200g pure water in every 500g honey juice, heating stirs well to obtain the final product after mixing, is processed with honey juice
The above Chinese medicine is to be conducive to clinical safety in order to reduce the toxic side effect of a part of bulk pharmaceutical chemicals and change its raw medicine and use and mention
High curative effect；
S5,15 parts by weight of blackberry lily that will be made, 15 parts by weight of subprostrate sophora, 5 parts by weight of myrrh, 5 parts by weight of Lasiosphaera fenzlii, Radix Glycyrrhizae 5
Parts by weight are mixed in investment wall-breaking machine and are ground into 300 mesh powders, collect spare；
S6,5 parts by weight of blackberry lily piece, 5 parts by weight of subprostrate sophora, 5 parts by weight of myrrh, 5 parts by weight of Radix Glycyrrhizae, 5 weight of Lasiosphaera fenzlii are separately taken
In part investment stainless-steel pan, sesame oil is added, sesame oil lid is crossed bulk pharmaceutical chemicals and is preferred, specifically, the oily medicine weight of sesame oil and bulk pharmaceutical chemicals
It than being heated to 180-200 degree after impregnating 24 hours for 5:3, and stirs, fries to bulk pharmaceutical chemicals with Cauterize for degree, filter out dregs of a decoction investment filter
Core machine gets rid of net sesame oil attachment, and it is spare to be ground into 300 mesh fine powders, here, squeeze decoction with sesame oil, improve these bulk pharmaceutical chemicals at
The stability divided；
S7, it takes in the oily decoction that is squeezed of 6 parts by weight of colophony powder investment and stirs, be heated to 60 degree and be completely melt to colophony powder
Oily medicine rosin stream cream is made in filtering afterwards, spare；
S8, the raw material medicinal powder of above-mentioned all crushing is merged, puts into stainless steel cauldron and stirs evenly, oily medicine rosin is added
Cream is flowed, it is spare to stir well into medicine puree；
S9, above-mentioned medicine puree is added in matrix, Silica hydrogel paste is made.
Specifically, matrix includes following components:
Medical use liquid silicon coagulates 12.7 parts by weight of gel,
0.8 parts by weight of carmethose,
6 parts by weight of colophony powder,
0.5 parts by weight of lanolin,
1.5 parts by weight of azone,
2 parts by weight of borneol.
The making step of the matrix is as follows:
12.7 part by weight of liquid Silica hydrogels are put into stainless-steel pan, with 0.3 parts by weight of ethanol by carmethose 0.8
Parts by weight, 0.5 parts by weight of lanolin dissolve by heating, and are then added in stainless-steel pan, add 1.5 parts by weight azones, 2 weights are added
Amount part borneol powder stir evenly the matrix, wherein colophony powder has added in the step s 7, uses as sticker, cure
Liquid silicone gel is used to use as colloidal materials, antelope methylcellulose sodium is used as crosslinking agent, and lanolin is used as moisturizer,
Azone is used as penetrating agent, and borneol is used as synergist.
Further, the matrix for being mixed with medicine puree is stirred evenly, pinches into ointment, remove the ointment investment stainless steel cooked flake wrapping machine
In, be pressed into 1.5mm thickness cream cake, cream cake be cut into 3.5cm × 3.5cm circle lotion, then by round lotion it is viscous be pressed in it is medical
On spun laced fabric, anti-sticking oilpaper in lotion face pressure is cut into edge greater than lotion 6cm × 4.5cm ellipse backing, and then pack is sealed
Mouthful, finished product silica gel paste is made, easily facilitates and carries and uses, the finished product silica gel paste dose is relatively light, and children is suitble to suffer from
Person uses.
Embodiment five:
The embodiment of the present invention also provides a kind of preparation method of external application Chinese medicine for treating tonsillitis and abscess of throat, including with
Lower step:
S1,20 parts by weight of 20 parts by weight of blackberry lily and subprostrate sophora are taken, while put into stainless-steel pan, be 6 degree with acetate concentration
1.5 parts by weight spray-stain of acetum stir well, here, with the Shanxi mature vinegar better effect of 6 degree of pure brewings, lid pot bored 3 hours
Afterwards, small fire heats, and fries to micro- that have macula lutea taking-up to dry spare, and processing above Chinese medicine with acetic acid is to reduce a part of bulk pharmaceutical chemicals
Toxic side effect and change its raw medicine, be conducive to clinical safety and use and improve curative effect；
S2, take in 10 parts by weight of myrrh investment stainless-steel pan, mild fire heating, fry it is micro- molten to the surface that smolders, cease fire it is micro- it is cool after,
The 0.75 parts by weight spray-stain of acetum for being 6 degree with acetate concentration stirs well reheating and fries to the glossy taking-up in surface and dries spare, use
It is to be conducive to clinical safety to reduce the toxic side effect of a part of bulk pharmaceutical chemicals and change its raw medicine that acetic acid, which processes the above Chinese medicine,
Use and improve curative effect；
S3, it takes in 10 parts by weight of sheet Lasiosphaera fenzlii investment stainless-steel pan, is sprayed with 0.75 parts by weight of honey juice that concentration is 60%
Lasiosphaera fenzlii in stain pot, stirs well, small fire heat micro- stir-frys taking-up dry it is spare, here, honey juice concentration is weight concentration, 60% honey
Juice, i.e., honey containing 300g, 200g pure water in every 500g honey juice, heating stirs well to obtain the final product after mixing, processed with honey juice more than
Chinese medicine is to be conducive to clinical safety in order to reduce the toxic side effect of a part of bulk pharmaceutical chemicals and change its raw medicine and use and improve treatment
Effect；
S4, it takes in 10 parts by weight of sheet Radix Glycyrrhizae investment stainless-steel pan, is sprayed with 0.75 parts by weight of honey juice that concentration is 60%
Lasiosphaera fenzlii in stain pot, stirs well, small fire heating, fries to there is a Cauterize spot, taking-up dry it is spare, here, honey juice concentration is weight concentration,
60% honey juice, i.e., honey containing 300g, 200g pure water in every 500g honey juice, heating stirs well to obtain the final product after mixing, with honey juice
Processing the above Chinese medicine is to be conducive to clinical safety use to reduce the toxic side effect of a part of bulk pharmaceutical chemicals and change its raw medicine
With raising curative effect；
S5,20 parts by weight of blackberry lily that will be made, 20 parts by weight of subprostrate sophora, 10 parts by weight of myrrh, 10 parts by weight of Lasiosphaera fenzlii, Radix Glycyrrhizae
10 parts by weight are mixed in investment wall-breaking machine and are ground into 300 mesh powders, collect spare；
S6,5 parts by weight of blackberry lily piece, 5 parts by weight of subprostrate sophora, 5 parts by weight of myrrh, 5 parts by weight of Radix Glycyrrhizae, 5 weight of Lasiosphaera fenzlii are separately taken
In part investment stainless-steel pan, sesame oil is added, sesame oil lid is crossed bulk pharmaceutical chemicals and is preferred, specifically, the oily medicine weight of sesame oil and bulk pharmaceutical chemicals
It than being heated to 180-200 degree after impregnating 24 hours for 5:3, and stirs, fries to bulk pharmaceutical chemicals with Cauterize for degree, filter out dregs of a decoction investment filter
Core machine gets rid of net sesame oil attachment, and it is spare to be ground into 300 mesh fine powders, here, squeeze decoction with sesame oil, improve these bulk pharmaceutical chemicals at
The stability divided；
S7, it takes in the oily decoction that is squeezed of 6 parts by weight of colophony powder investment and stirs, be heated to 60 degree and be completely melt to colophony powder
Oily medicine rosin stream cream is made in filtering afterwards, spare；
S8, the raw material medicinal powder of above-mentioned all crushing is merged, puts into stainless steel cauldron and stirs evenly, oily medicine rosin is added
Cream is flowed, it is spare to stir well into medicine puree；
S9, above-mentioned medicine puree is added in matrix, Silica hydrogel paste is made.
Specifically, matrix includes following components:
Medical use liquid silicon coagulates 12.7 parts by weight of gel,
0.8 parts by weight of carmethose,
6 parts by weight of colophony powder,
0.5 parts by weight of lanolin,
1.5 parts by weight of azone,
2 parts by weight of borneol.
The making step of the matrix is as follows:
12.7 part by weight of liquid Silica hydrogels are put into stainless-steel pan, with 0.3 parts by weight of ethanol by carmethose 0.8
Parts by weight, 0.5 parts by weight of lanolin dissolve by heating, and are then added in stainless-steel pan, add 1.5 parts by weight azones, 2 weights are added
Amount part borneol powder stir evenly the matrix, wherein colophony powder has added in the step s 7, uses as sticker, cure
Liquid silicone gel is used to use as colloidal materials, antelope methylcellulose sodium is used as crosslinking agent, and lanolin is used as moisturizer,
Azone is used as penetrating agent, and borneol is used as synergist.
Further, the matrix for being mixed with medicine puree is stirred evenly, pinches into ointment, remove the ointment investment stainless steel cooked flake wrapping machine
In, be pressed into 1.5mm thickness cream cake, cream cake be cut into 3.5cm × 3.5cm circle lotion, then by round lotion it is viscous be pressed in it is medical
On spun laced fabric, anti-sticking oilpaper in lotion face pressure is cut into edge greater than lotion 6cm × 4.5cm ellipse backing, and then pack is sealed
Mouthful, finished product silica gel paste is made, easily facilitates and carries and uses, the finished product silica gel paste dose is medium, and suitable general patient makes
With.
Embodiment six:
The embodiment of the present invention also provides a kind of preparation method of external application Chinese medicine for treating tonsillitis and abscess of throat, including with
Lower step:
S1,25 parts by weight of 25 parts by weight of blackberry lily and subprostrate sophora are taken, while put into stainless-steel pan, be 6 degree with acetate concentration
1.8 parts by weight spray-stain of acetum stir well, here, with the Shanxi mature vinegar better effect of 6 degree of pure brewings, lid pot bored 3 hours
Afterwards, small fire heats, and fries to micro- that have macula lutea taking-up to dry spare, and processing above Chinese medicine with acetic acid is to reduce a part of bulk pharmaceutical chemicals
Toxic side effect and change its raw medicine, be conducive to clinical safety and use and improve curative effect；
S2, take in 15 parts by weight of myrrh investment stainless-steel pan, mild fire heating, fry it is micro- molten to the surface that smolders, cease fire it is micro- it is cool after,
The 1.1 parts by weight spray-stain of acetum for being 6 degree with acetate concentration stirs well reheating and fries to the glossy taking-up in surface and dries spare, use
It is to be conducive to clinical safety to reduce the toxic side effect of a part of bulk pharmaceutical chemicals and change its raw medicine that acetic acid, which processes the above Chinese medicine,
Use and improve curative effect；
S3, it takes in 15 parts by weight of sheet Lasiosphaera fenzlii investment stainless-steel pan, the 1 parts by weight spray-stain pot of honey juice for being 60% with concentration
Interior Lasiosphaera fenzlii, stirs well, small fire heat micro- stir-frys taking-up dry it is spare, here, honey juice concentration is weight concentration, 60% honey juice, i.e.,
Honey containing 300g, 200g pure water in every 500g honey juice, heating stirs well to obtain the final product after mixing, and processing the above Chinese medicine with honey juice is
In order to reduce the toxic side effect of a part of bulk pharmaceutical chemicals and change its raw medicine, is conducive to clinical safety and uses and improve curative effect；
S4, it takes in 15 parts by weight of sheet Radix Glycyrrhizae investment stainless-steel pan, the 1 parts by weight spray-stain pot of honey juice for being 60% with concentration
Interior Lasiosphaera fenzlii, stirs well, small fire heating, fries to there is a Cauterize spot, taking-up dry it is spare, here, honey juice concentration is weight concentration, 60% bee
Honeydew, i.e., honey containing 300g, 200g pure water in every 500g honey juice, after mixing heating stir well to obtain the final product, with honey juice process with
Upper Chinese medicine is to be conducive to clinical safety in order to reduce the toxic side effect of a part of bulk pharmaceutical chemicals and change its raw medicine and use and improve
Curative effect；
S5,25 parts by weight of blackberry lily that will be made, 25 parts by weight of subprostrate sophora, 15 parts by weight of myrrh, 15 parts by weight of Lasiosphaera fenzlii, Radix Glycyrrhizae
15 parts by weight are mixed in investment wall-breaking machine and are ground into 300 mesh powders, collect spare；
S6,5 parts by weight of blackberry lily piece, 5 parts by weight of subprostrate sophora, 5 parts by weight of myrrh, 5 parts by weight of Radix Glycyrrhizae, 5 weight of Lasiosphaera fenzlii are separately taken
In part investment stainless-steel pan, sesame oil is added, sesame oil lid is crossed bulk pharmaceutical chemicals and is preferred, specifically, the oily medicine weight of sesame oil and bulk pharmaceutical chemicals
It than being heated to 180-200 degree after impregnating 24 hours for 5:3, and stirs, fries to bulk pharmaceutical chemicals with Cauterize for degree, filter out dregs of a decoction investment filter
Core machine gets rid of net sesame oil attachment, and it is spare to be ground into 300 mesh fine powders, here, squeeze decoction with sesame oil, improve these bulk pharmaceutical chemicals at
The stability divided；
S7, it takes in the oily decoction that is squeezed of 6 parts by weight of colophony powder investment and stirs, be heated to 60 degree and be completely melt to colophony powder
Oily medicine rosin stream cream is made in filtering afterwards, spare；
S8, the raw material medicinal powder of above-mentioned all crushing is merged, puts into stainless steel cauldron and stirs evenly, oily medicine rosin is added
Cream is flowed, it is spare to stir well into medicine puree；
S9, above-mentioned medicine puree is added in matrix, Silica hydrogel paste is made.
Specifically, matrix includes following components:
Medical use liquid silicon coagulates 12.7 parts by weight of gel,
0.8 parts by weight of carmethose,
6 parts by weight of colophony powder,
0.5 parts by weight of lanolin,
1.5 parts by weight of azone,
2 parts by weight of borneol.
The making step of the matrix is as follows:
12.7 part by weight of liquid Silica hydrogels are put into stainless-steel pan, with 0.3 parts by weight of ethanol by carmethose 0.8
Parts by weight, 0.5 parts by weight of lanolin dissolve by heating, and are then added in stainless-steel pan, add 1.5 parts by weight azones, 2 weights are added
Amount part borneol powder stir evenly the matrix, wherein colophony powder has added in the step s 7, uses as sticker, cure
Liquid silicone gel is used to use as colloidal materials, antelope methylcellulose sodium is used as crosslinking agent, and lanolin is used as moisturizer,
Azone is used as penetrating agent, and borneol is used as synergist.
Further, the matrix for being mixed with medicine puree is stirred evenly, pinches into ointment, remove the ointment investment stainless steel cooked flake wrapping machine
In, be pressed into 1.5mm thickness cream cake, cream cake be cut into 3.5cm × 3.5cm circle lotion, then by round lotion it is viscous be pressed in it is medical
On spun laced fabric, anti-sticking oilpaper in lotion face pressure is cut into edge greater than lotion 6cm × 4.5cm ellipse backing, and then pack is sealed
Mouthful, finished product silica gel paste is made, easily facilitates and carries and uses, the finished product silica gel paste dose is heavier, and severe patient is suitble to make
With.
Embodiment seven:
(1) test method: clinical use；
(2) test unit: Weifang affiliated hospital department of traditional Chinese medicine, internal medicine:
(3) the acute tonsillitis of selection of clinical, abscess of throat patient 60.Male 30, female 30, average age 27.5
It is divided into two groups in year, control group a includes male 15, and women 15, control group b includes male 15, women 15, two groups of trouble
Person the age, gender, clinical symptoms and in terms of data difference it is not significant (P < 0.05), it is not statistically significant, have
Comparativity；
(4) diagnostic criteria: obvious abscess of throat, pharyngeal rear wall and almond mucous hyperemia, swelling, cryptae tonsillares have purulence
Secretion is aching and limp etc. with part whole body.
(5) treatment method: treatment group is disappeared external use plaster using laryngalgia of the invention, everyone, which divides 1 time, daily sticks, and is sticked
Time is 2-10 hours, 3 days as one therapeutic course.
(6) efficacy assessment standard:
Recovery from illness: the symptoms such as abscess of throat all disappear, and tonsillotome is red and swollen to disappear substantially；
Fever, the symptoms were significantly improved for abscess of throat etc., and tonsillotome is red and swollen, and crypts purulent secretion disappears substantially, ulcer surface
It reduces；
Invalid: clinical symptoms are not improved；
(7) treatment results:
Control group a: occupying clinical use Eexternal-use Chinese medicine plaster of the present invention, suffers from through application treatment 15 male patients and 15 female
Person, symptom substantially eliminates after sticking 1 course for the treatment of, 29 people recovery from illness, and 1 male patient improves, total effective rate 98%；
B:15 male patients of control group and 15 female patients Cefaclor, roxithromycin, cooperation Pudilan anti-inflammatory by oral administration
Oral solution, body temperature surpass 38.5 degree, can cooperate and dissipate the heat dissipation analgesic such as sharp pain, Fenbid, 2-3 times daily, control through 1 course for the treatment of
It treats, fully recovers 19, improve 2 male patients and 3 female patients, separately has 4 male patients and 2 female patients invalid, total effective rate is
83%.
Typical case 1:
Patient Zhang, male, 6 years old, main suit's pharyngeal pain, odynophagia very, was had a fever 2 days, patient is before 2 days, because eating fish hot pot
Pharyngeal appearance is uncomfortable afterwards, then pain, and 38.2 DEG C of measurement body temperature are given anti-inflammatory agent treatment of bringing down a fever in personal hygiene room, treats aftereffect
Fruit is bad, then carrys out affiliated hospital's department of traditional Chinese medicine and seeks medical advice, upon examination it is found that left side tonsillotome redness I degree enlargement, it is seen that has white point
Secretion attachment, measures 37.9 DEG C of body temperature.Chinese medicine plaster for external application 2 of the present invention is sticked in almond body position to paste, and family numbers of patients is advised to take back 6 patches
It goes home oneself to stick, exhorts the further consultation of the 4th Tian Lai institute of family numbers of patients, the 4th day family numbers of patients comes the court's Chinese medicine with 6 years old son
Section, through further consultation inspection, pharyngalgia, fever disappear, only left side I degree enlargement, recovery from illness.Exhort that family numbers of patients goes home to be careful in one's diet with clear
Based on light.
Typical case 2:
Patient Wang Nvshi, 25 years old.Main suit: having sore throat 5 days, and the medicines such as Administration of roxithromycin capsule are ineffective, attached with coming
Belong to hospital's department of traditional Chinese medicine to seek medical advice, hospital checks that pharynx rear wall is congested, and bilateral amygdala I degree is red and swollen, there is ulcer surface, and tongue is red, and yellow tongue fur is thick, arteries and veins
Chord number.It is explained through doctor and sticks the patch of Chinese medicine plaster for external application two of the present invention, be pasted on bilateral pain spot and three, Tiantu cave position respectively, paste
10 hours of time are applied, exhort manifold card three days；
Two examine: having sore throat and disappeared, redness is big, ulcer is slightly worse, continues to stick three patches, exhorts that third day continues to stick；
Three examine: hyperemia disappears, ulcer surface reduces, and enlargement is slightly smaller, continues to stick.
The four methods of diagnosis: school checks that only enlargement is slightly worse, and other symptoms completely disappear, fully recover.
Typical case 3:
Patient Zhang, male 35 years old, main suit ate barbecue before three days, pharyngalgia occur, generated heat after having foreign body sensation, oral paracetamol
Slightly decline with body temperature behind Amoxicillin, pharyngalgia aggravates, and hospital checks 38.8 DEG C of bilateral amygdala III degree rednesses of body temperature at scarlet
Color, and there is pus point on surface, pharynx rear wall is congested obvious, and leukocyte count 12.4*109/L is diagnosed as acute tonsillitis.Using this hair
Bright Chinese medicine plaster for external application sticks 5 patches, respectively at bilateral pain spot, Tiantu cave, left and right yangsi (Jing-River Point,LI 5) cave；
Two examine: pain substantially eliminates, and body temperature is down to 37.2 DEG C, and redness is shown in small, pus point atrophy, sticks ibid after again.
Three examine: 36.9 DEG C of body temperature, pain disappears, and pharynx rear wall hyperemia is normal, and enlargement is slightly worse, pus point reduces.
The four methods of diagnosis: only enlargement I degree, other symptoms, which disappear, fully recovers.
Typical case 4:
Patient Sun 10 years old, blows air-conditioning and catches a cold, have sore throat, fever, aversion to cold, the anti-breaking-out of oral medication fever, mouth
Dry, hospital checks, 38.4 DEG C of bilateral amygdala II degree enlargements of body temperature, and surface has dense tongue fur to cover, red tongue with yellowish and greasy fur, and leucocyte is neutral
Granulocyte is higher, diagnoses acute tonsillitis.The yangsi (Jing-River Point,LI 5) of bilateral pain spot, Tiantu cave, left and right is sticked using Chinese medicine plaster for external application of the present invention
Cave 5 is pasted totally, substantially eliminates recovery from illness through 3 days application treatment symptomatologies.According to the above result shows that being verified with a large amount of clinical diseases
Chinese medicine plaster for external application of the present invention has significant curative effect to tonsillitis, abscess of throat, and trier does not occur uncomfortable phenomenon, every
Indexs measure is normal, does not occur adverse events.
The external application Chinese medicine of experiment conclusion, the treatment tonsillitis and abscess of throat uses pure Chinese medicinal preparation, realizes outside Chinese medicine
With by fried good Chinese medicine setting on medical spun laced fabric, direct point-application is used when needing, and stimulating intestine and stomach, does not solve
In the prior art oral traditional Chinese medicine it is fried it is cumbersome, side effect is big when taking and the technical issues of being also easy to produce adverse reaction.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention are fallen within the scope of the claimed invention.
Claims (7)
1. a kind of external application Chinese medicine for treating tonsillitis and abscess of throat, which is characterized in that including following components: blackberry lily 20-30 weight
Measure part, subprostrate sophora 20-30 parts by weight, myrrh 10-20 parts by weight, Lasiosphaera fenzlii 10-20 parts by weight, Radix Glycyrrhizae 10-20 parts by weight.
2. a kind of preparation method for the external application Chinese medicine for treating tonsillitis and abscess of throat, which comprises the following steps:
S1, blackberry lily 15-25 parts by weight and subprostrate sophora 15-25 parts by weight are taken, while put into stainless-steel pan, be 6 with acetate concentration
The acetum 1.2-1.8 parts by weight spray-stain of degree stirs well, and after lid pot bored 3 hours, small fire heating, frying to micro- has macula lutea taking-up to dry
It is spare；
S2, take in myrrh 5-15 parts by weight investment stainless-steel pan, mild fire heating, fry it is micro- molten to the surface that smolders, cease fire it is micro- it is cool after, use
Acetate concentration is 6 degree of acetum 0.4-1.1 parts by weight spray-stain, stir well reheating fry to surface it is glossy take out dry it is spare；
S3, it takes in sheet Lasiosphaera fenzlii 5-15 parts by weight investment stainless-steel pan, the honey juice 0.5-1 parts by weight spray-stain for being 60% with concentration
Lasiosphaera fenzlii in pot, stirs well, and the micro- stir-fry taking-up of small fire heating is dried spare；
S4, it takes in sheet Radix Glycyrrhizae 5-15 parts by weight investment stainless-steel pan, the honey juice 0.5-1 parts by weight spray-stain for being 60% with concentration
Lasiosphaera fenzlii in pot, stirs well, small fire heating, fries to there is Cauterize spot, taking-up is dried spare；
S5, the blackberry lily 15-25 parts by weight that will be made, subprostrate sophora 15-25 parts by weight, myrrh 5-15 parts by weight, Lasiosphaera fenzlii 5-15 weight
Part, Radix Glycyrrhizae 5-15 parts by weight are mixed in investment wall-breaking machine and are ground into 300 mesh powders, collect spare；
S6,5 parts by weight of blackberry lily piece, 5 parts by weight of subprostrate sophora, 5 parts by weight of myrrh, 5 parts by weight of Radix Glycyrrhizae, 5 parts by weight of Lasiosphaera fenzlii are separately taken to throw
Enter in stainless-steel pan, sesame oil be added, be heated to 180-200 degree after impregnating 24 hours, and stir, fries to bulk pharmaceutical chemicals with Cauterize for degree,
It filters out dregs of a decoction investment filter core machine and gets rid of net sesame oil attachment, it is spare to be ground into 300 mesh fine powders；
S7, take in the oily decoction that is squeezed of 6 parts by weight of colophony powder investment and stir, be heated to 60 degree be completely melt to colophony powder after mistake
Oily medicine rosin stream cream is made in filter, spare；
S8, the raw material medicinal powder of above-mentioned all crushing is merged, puts into stainless steel cauldron and stirs evenly, oily medicine rosin stream is added
It is spare to stir well into medicine puree for cream；
S9, above-mentioned medicine puree is added in matrix, Silica hydrogel paste is made.
3. the preparation method for the treatment of tonsillitis according to claim 2 and the external application Chinese medicine of abscess of throat, which is characterized in that
The matrix includes following components:
Medical use liquid silicon coagulates 12.7 parts by weight of gel,
0.8 parts by weight of carmethose,
6 parts by weight of colophony powder,
0.5 parts by weight of lanolin,
1.5 parts by weight of azone,
2 parts by weight of borneol.
4. the preparation method for the treatment of tonsillitis according to claim 3 and the external application Chinese medicine of abscess of throat, which is characterized in that
The making step of the matrix is as follows:
12.7 part by weight of liquid Silica hydrogels are put into stainless-steel pan, with 0.3 parts by weight of ethanol by 0.8 weight of carmethose
Part, 0.5 parts by weight of lanolin dissolve by heating, and are then added in stainless-steel pan, add 1.5 parts by weight azones, 2 parts by weight are added
Borneol powder stir evenly the matrix.
5. the preparation method for the treatment of tonsillitis according to claim 3 or 4 and the external application Chinese medicine of abscess of throat, feature exist
In, the matrix for being mixed with medicine puree is stirred evenly, ointment is pinched into, remove the ointment investment stainless steel cooked flake wrapping machine in, be pressed into 1.5mm thickness
Cream cake is spent, cream cake is cut into 3.5cm × 3.5cm circle lotion, then round lotion is glued and is pressed on medical spun laced fabric, lotion face
Anti-sticking oilpaper in pressure is cut into edge greater than lotion 6cm × 4.5cm ellipse backing, and then pack sealing, is made finished product silica gel
Paste.
6. the preparation method for the treatment of tonsillitis according to claim 2 and the external application Chinese medicine of abscess of throat, which is characterized in that
In step s 6, sesame oil lid crosses bulk pharmaceutical chemicals.
7. the preparation method for the treatment of tonsillitis according to claim 6 and the external application Chinese medicine of abscess of throat, which is characterized in that
The oily medicine weight ratio of sesame oil and bulk pharmaceutical chemicals is 5:3.
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Citations (2)
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| CN102247452A (en) * | 2010-12-16 | 2011-11-23 | 姜绪东 | Prescription for treating influenza |
| CN103191321A (en) * | 2013-04-10 | 2013-07-10 | 成都中医药大学 | Pharmaceutical composition for treating tonsillitis and preparation method and application thereof |
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2019
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247452A (en) * | 2010-12-16 | 2011-11-23 | 姜绪东 | Prescription for treating influenza |
| CN103191321A (en) * | 2013-04-10 | 2013-07-10 | 成都中医药大学 | Pharmaceutical composition for treating tonsillitis and preparation method and application thereof |
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| 盛华刚主编: "《中药药剂学课堂笔记》", 31 October 2018, 同济大学出版社 * |
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Application publication date: 20191119 |