CN110455982B

CN110455982B - Automatic titration device capable of simultaneously carrying out multi-sample inspection

Info

Publication number: CN110455982B
Application number: CN201910796615.2A
Authority: CN
Inventors: 刘春艳; 周迪昊; 刘毅
Original assignee: Jiangxi Yukang Pharmaceutical Co ltd
Current assignee: Jiangxi Yukang Pharmaceutical Co.,Ltd.
Priority date: 2019-08-27
Filing date: 2019-08-27
Publication date: 2021-08-24
Anticipated expiration: 2039-08-27
Also published as: CN110455982A

Abstract

The invention relates to the technical field of medicine processing, and discloses an automatic titration device capable of simultaneously carrying out multi-sample inspection, which comprises a stand, wherein a test tube disc is fixedly connected to the outer side of the stand; set up a plurality of spacing holes, be convenient for place a plurality of sample bottles and titrate simultaneously, accelerate and titrate efficiency, can have the spacing effect of centering to the sample bottle of multiple size, make the solution accuracy in the stock solution bottle fall into the sample bottle, the bull stick drives the carousel rotation and arouses the clamp plate to reciprocate, provide the power supply for extrusion and the pushing down of stock solution bottle of follow-up rubber tube, the linkage nature of device has been increased, it is more convenient to make the operation, avoid artifical manual titrating, liberation both hands, reduce working strength, reduce experimental error, the bull stick drives gear revolve and arouses the ratch to carry out spiral orbit and rotates, it rotates in step to drive the stock solution bottle, its orbit is unanimous with the orbit that sets up in spacing hole, make the stock solution bottle be located the top in spacing hole all the time, guarantee to titrat.

Description

Automatic titration device capable of simultaneously carrying out multi-sample inspection

Technical Field

The invention relates to the technical field of medicine processing, in particular to an automatic titration device capable of simultaneously carrying out multi-sample inspection.

Background

The medicine processing refers to a process that raw materials are changed into new medicine products after physical change or chemical change, the medicine processing process is closely related to the state of the raw materials and the final form of the medicine, but quality inspection is an indispensable process to ensure the qualification, safety and reliability of the medicine quality, wherein titration inspection is one of common inspection methods, the titration inspection is used for detecting the content of main components of the medicine, the inspection speed is high, the accuracy is high, the used instrument is simple, and the following problems exist in the conventional titration inspection of the medicine:

the common titration device can not simultaneously titrate a plurality of samples, needs to titrate for a plurality of times, is inconvenient to operate, can not effectively and fixedly clamp sample bottles with different sizes, and the prior titration work is manually operated, has large task amount, complex operation and low work efficiency when a large number of samples are titrated, has larger human error, thus the credibility of test data is low,

aiming at the defects of the prior art, the invention provides the automatic titration device capable of simultaneously carrying out multi-sample detection, which has the advantage of simultaneously carrying out titration on a plurality of samples, solves the problem of low working efficiency, simultaneously carries out titration on a plurality of sample bottles, accelerates the titration efficiency, has the functions of centering and limiting the sample bottles with various sizes, ensures that the solution in the solution storage bottle accurately falls into the sample bottle, is convenient for the smooth test, increases the linkage of the device, ensures that the operation is more convenient, avoids manual titration, frees both hands, reduces the working strength, avoids the situation of solution splashing in the titration process, reduces the test error, increases the authenticity of data, ensures that the solution storage bottle is always positioned above a limiting hole, avoids the problem that the solution cannot drip into the sample bottle due to the track deviation, and ensures the smooth operation of the titration.

Disclosure of Invention

Technical scheme (I)

In order to realize the purpose of carrying out titration on a plurality of samples simultaneously, the invention provides the following technical scheme: the utility model provides an automatic titration device that can carry out many sample inspections simultaneously, the camera includes the pallet, the outside fixedly connected with test tube dish of pallet, spacing hole has been seted up to the inside of test tube dish, the inside swing joint in spacing hole has the clamp splice, the outside fixedly connected with branch of pallet, the inside swing joint of branch has the bull stick, the outside fixedly connected with carousel of bull stick, the outside swing joint of carousel has the carriage release lever, the outside fixedly connected with limiting plate of carriage release lever, the bottom fixedly connected with clamp plate of carriage release lever, the below swing joint of clamp plate has the stock solution bottle, the top fixedly connected with rubber tube of stock solution bottle, the outside fixedly connected with movable block of stock solution bottle, the bottom fixedly connected with drain pipe of stock solution bottle, the inside swing joint of drain pipe has the valve block, the outside fixedly connected with gear of bull stick, the outside fixedly connected with movable block of gear, the bottom swing joint of movable block has the ratch.

Preferably, spacing hole has a plurality ofly and the size is unanimous to the heliciform equidistance distributes in the inside of test tube dish, and the slotted hole that the size is the same is seted up to the inner wall of spacing hole both sides, and two slotted holes use the axis in spacing hole to present the symmetric distribution as the reference, and the clamp splice has two and the size is the same, and the clamp splice activity card is in its slotted hole, and the outside swing joint of clamp splice has the spring, and one side that the clamp splice was kept away from to the spring is connected with the inside swing joint of slotted hole.

Preferably, the outer wall surface of the turntable is provided with wavy channels with the same size, the wavy channels are matched with the moving rod in size, the moving rod is movably clamped in the groove of the moving rod, and when the turntable rotates, the wavy channels on the surface of the turntable drive the moving rod to move up and down.

Preferably, the movable rod has two and the size is unanimous, and two the same holes of size are seted up to the inside of limiting plate, and its size and the size looks adaptation of movable rod, and the movable rod fixing clip is in its hole and fixed connection is in the both sides of clamp plate.

Preferably, the size of the pressure plate is greater than the spiral size that spacing hole formed to the unable stock solution bottle that extrudees of pressure plate leads to the sample bottle in the spacing downthehole of part can not titrate.

Preferably, the holes are formed in the turnplate, the limiting plate and the pressing plate, the size of the hole of the turnplate is matched with that of the rotating rod, and the size of the hole of the limiting plate and the size of the pressing plate are larger than that of the rotating rod.

Preferably, the bottom of the movable block is movably connected with two springs with the same specification, the springs are symmetrically distributed by taking the central axis of the movable block as a reference, and the bottoms of the springs are movably connected with the toothed bar.

Preferably, the size of gear and the size looks adaptation of ratch make the gear rotate the synchronous rotation of drive ratch, and the channel has been seted up on the surface of ratch, and the size looks adaptation of its size and movable block makes the movable block when rotating along with the gear, drives ratch and gear engagement and presents the spiral rotation, and movable block activity card is in its channel, and the via hole has been seted up to the inside of ratch, the size of its size and the size looks adaptation of stock solution bottle, and stock solution bottle activity card is in its via hole.

(II) advantageous effects

Compared with the prior art, the invention provides an automatic titration device capable of simultaneously carrying out multiple sample tests, which has the following beneficial effects:

1. under the combined action through spacing hole and clamp splice, set up a plurality of spacing holes, be convenient for place a plurality of sample bottles and titrate simultaneously, accelerate to titrate efficiency, reduce experimental error, increase the credibility of experimental data, the sample bottle is placed in spacing downthehole, make the clamp splice centre gripping in the both sides of sample bottle, can have the spacing effect of centering to the sample bottle of multiple size, make the sample bottle keep standing, make the solution accuracy in the stock solution bottle fall into the sample bottle in, be convenient for go on smoothly experimental.

2. Under the combined action through bull stick, carousel, carriage release lever, limiting plate and clamp plate, the bull stick drives the carousel rotation and arouses the clamp plate to reciprocate, for the extrusion of follow-up rubber tube and the pushing down of stock solution bottle provide the power supply, has increased the linkage nature of device, makes the operation more convenient.

3. Through the clamp plate, the stock solution bottle, the rubber tube, the movable block, under the combined action of drain pipe and valve block, the clamp plate pushes down and drives the rubber tube and warp and the stock solution bottle moves down, arouse in the stock solution bottle pressure grow to break away the valve block, make the solution in the stock solution bottle flow from the drain pipe, avoid artifical manual titration, liberation both hands, reduce working strength, and the drain pipe of stock solution bottle is close to the sample bottle, avoid because the drain pipe leads to titrating the condition that the in-process solution splashes with the problem of sample bottle distance, reduce test error, increase the authenticity of data.

4. Under the combined action through bull stick, gear, movable block, ratch, spacing hole and stock solution bottle, the bull stick drives gear revolve and arouses the ratch to carry out the spiral orbit and rotates, drives the stock solution bottle and rotates in step, and its orbit is unanimous with the orbit that sets up in spacing hole, makes the stock solution bottle be located the top in spacing hole all the time, avoids in the orbit deviation leads to the unable drippage sample bottle of solution, guarantees going on smoothly of titration work.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is an enlarged view of the structure of FIG. 1 at A according to the present invention;

FIG. 3 is a schematic view of the connection relationship between the test tube plate and the limiting hole according to the present invention;

FIG. 4 is a schematic view of the connection relationship between the structure limiting hole and the clamping block;

FIG. 5 is a schematic view of the connection between the turntable and the pressing plate according to the present invention, wherein the structures are at the initial positions and do not change positions;

FIG. 6 is a schematic diagram showing the movement traces of the turntable and the pressing plate according to the present invention, wherein the turntable rotates to drive the pressing plate to move downward;

FIG. 7 is a schematic view of the connection between the gear and the rack of the present invention, wherein the structures are at the initial positions and are not changed in position;

FIG. 8 is a schematic diagram of the movement traces of the gear and the rack in the present invention, wherein the gear rotates to drive the rack to rotate spirally.

In the figure: the device comprises a rack 1, a test tube plate 2, a limiting hole 3, a clamping block 4, a supporting rod 5, a rotating rod 6, a rotating disk 7, a moving rod 8, a limiting plate 9, a pressing plate 10, a liquid storage bottle 11, a rubber tube 12, a moving block 13, a liquid outlet tube 14, a valve plate 15, a gear 16, a moving block 17 and a toothed bar 18.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-8, an automatic titration apparatus capable of simultaneously inspecting multiple samples comprises a stand 1, a test tube tray 2 fixedly connected to the outer side of the stand 1, a plurality of limiting holes 3 formed in the test tube tray 2, the limiting holes 3 having the same size and being convenient for multiple experiments at the same time, the limiting holes 3 being equally distributed in the test tube tray 2 in a spiral shape, since the solution in the solution storage bottle 11 is dripped into the sample bottle in the same period, the limiting holes 3 for placing the sample bottle are equally distributed to ensure the solution in the solution storage bottle 11 to accurately fall into the sample bottle, the inner walls of the limiting holes 3 having the same size and being symmetrically distributed with the central axis of the limiting hole 3 as a reference, two clamping blocks 4 having the same size and being movably clamped in the slots, a spring movably connected to the outer side of the clamping block 4, one side of the spring away from the clamping block 4 being movably connected with the inner portions of the slots, clamp splice 4 has the fixed effect of centre gripping to the sample bottle of multiple size can be held to the sample bottle, the inside swing joint in spacing hole 3 has clamp splice 4, the outside fixedly connected with branch 5 of pallet 1.

The inside swing joint of the fulcrum bar 5 has the rotary bar 6, the outside of the rotary bar 6 is fixedly connected with the rotary table 7, the outer wall surface of the rotary table 7 offers the wavy channel with identical size, its size is identical to size of the movable rod 8, the movable rod 8 activity card is in its recess, when making the rotary table 7 rotate, the wavy channel on its surface drives the movable rod 8 to move up and down, the outside swing joint of the rotary table 7 has the movable rod 8, the movable rod 8 has two and identical size, the inside of the limiting plate 9 offers two holes with identical size, its size is identical to size of the movable rod 8, in order to avoid the movable rod 8 to deflect while moving with the wavy channel of the rotary table 7, limit the position of the movable rod 8, make it keep vertical direction movement all the time, the movable rod 8 is fixedly card in its hole and fixedly connected to both sides of the clamp plate 10, make the clamp plate 10 keep horizontal placement, the outside fixedly connected with limiting plate 9 of carriage release lever 8, the hole has all been seted up to the inside of carousel 7, limiting plate 9 and clamp plate 10, and the size of 7 holes on carousel and the size looks adaptation of bull stick 6, the size in limiting plate 9 and the 10 holes on clamp plate all is greater than the size of bull stick 6, drives limiting plate 9 and clamp plate 10 synchronous rotation when avoiding bull stick 6 to rotate.

The bottom of the moving rod 8 is fixedly connected with a pressing plate 10, the size of the pressing plate 10 is larger than the spiral size formed by the limiting holes 3, so that the pressing plate 10 cannot extrude the liquid storage bottle 11, and the sample bottles in partial limiting holes 3 cannot be titrated, the liquid storage bottle 11 is movably connected below the pressing plate 10, the rubber tube 12 is fixedly connected above the liquid storage bottle 11, the outer side of the liquid storage bottle 11 is fixedly connected with a movable block 13, the bottom of the movable block 13 is movably connected with two springs with the same specification, the springs are symmetrically distributed by taking the central axis of the movable block 13 as reference, the bottoms of the springs are movably connected with a toothed rod 18, so that the movable block 13 automatically moves up to an initial position under the action of the springs when acting force of the pressing plate 10 in the urban area, the bottom of the liquid storage bottle 11 is fixedly connected with a liquid outlet tube 14, the inner part of the liquid outlet tube 14 is movably connected with a valve plate 15, the outer side of the rotating rod 6 is fixedly connected with a gear 16, the outside fixedly connected with movable block 17 of gear 16, the bottom swing joint of movable block 17 has ratch 18, the size of gear 16 and the size looks adaptation of ratch 18, it rotates to drive ratch 18 synchronous when making gear 16 rotate, the channel has been seted up on the surface of ratch 18, the size looks adaptation of its size and movable block 17, when making movable block 17 rotate along with gear 16, it appears the spiral rotation to drive ratch 18 and gear 16 meshing, movable block 17 activity card is in its channel, the via hole has been seted up to the inside of ratch 18, the size looks adaptation of its size and stock solution bottle 11, stock solution bottle 11 activity card is in its cross downthehole.

The working principle is that a sample bottle filled with medicine is placed in a limiting hole 3 of a test tube disc 2, a clamping block 4 is extruded by the sample bottle to move towards two sides and compress a spring, the spring also extrudes the clamping block 4 to fix the sample bottle, a starting power drives a rotating rod 6 to rotate through an output shaft, the rotating rod 6 drives a rotating disc 7 and a gear 16 to synchronously rotate, as the outer side surface of the rotating disc 7 is provided with a wavy channel, and a limiting plate 9 has a limiting function on a moving rod 8, when the rotating disc 7 rotates, the channel at the bulge and the recess of the rotating disc drives the moving rod 8 to continuously move upwards and downwards in the vertical direction, the moving rod 8 drives a pressing plate 10 to synchronously move, the pressing plate 10 is close to a rubber tube 12 to extrude the rubber tube and downwards extrude a movable block 13 to drive the liquid storage bottle 11 to synchronously downwards, so that a liquid outlet tube 14 is close to the sample, the rubber tube 12 is extruded to increase the pressure in the liquid storage bottle 11, and the pressure difference between the inside and the outside of the liquid storage bottle 11 flushes away a valve plate 15, the solution flows out of the liquid outlet pipe 14 and drops into the sample bottle, so that titration is completed; meanwhile, the gear 16 drives the moving block 17 to synchronously rotate, the moving block 17 is movably clamped in a channel of the rack bar 18 to drive the rack bar 18 to be meshed with the gear 16, spiral rotation occurs, the liquid storage bottle 11 is driven to also move spirally, the moving track is consistent with the track set by the limiting hole 3 on the test tube disc 2, the pressing plate 10 moves upwards again, a spring at the bottom of the moving block 13 drives the liquid storage bottle 11 to return to the initial position, the valve plate 15 returns to the original position due to the fact that the pressure inside and outside the liquid storage bottle 11 is consistent after being flushed away, the solution in the liquid storage bottle 11 stops dripping, the pressing plate 10 is located at the highest point, the liquid storage bottle 11 moves to the upper side of the next sample bottle along with the rack bar 18, and the next sample is continuously titrated.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a can carry out auto-titration device of inspection of many copies sample simultaneously, includes stand (1), its characterized in that: the test tube rack is characterized in that a test tube plate (2) is fixedly connected to the outer side of the rack (1), a limiting hole (3) is formed in the test tube plate (2), a clamping block (4) is movably connected to the inner portion of the limiting hole (3), a supporting rod (5) is fixedly connected to the outer side of the rack (1), a rotating rod (6) is movably connected to the inner portion of the supporting rod (5), a rotating disk (7) is fixedly connected to the outer side of the rotating rod (6), a moving rod (8) is movably connected to the outer side of the rotating disk (7), a limiting plate (9) is fixedly connected to the outer side of the moving rod (8), a pressing plate (10) is fixedly connected to the bottom of the moving rod (8), a liquid storage bottle (11) is movably connected to the lower portion of the pressing plate (10), a rubber tube (12) is fixedly connected to the upper portion of the liquid storage bottle (11), a moving block (13) is fixedly connected to the outer side of the liquid storage bottle (11), and a liquid outlet tube (14) is fixedly connected to the bottom of the liquid storage bottle (11), a valve plate (15) is movably connected inside the liquid outlet pipe (14), a gear (16) is fixedly connected to the outer side of the rotating rod (6), a moving block (17) is fixedly connected to the outer side of the gear (16), and a toothed bar (18) is movably connected to the bottom of the moving block (17);

the limiting holes (3) are multiple and consistent in size and are distributed in the test tube tray (2) in a spiral shape at equal intervals, the inner walls of two sides of each limiting hole (3) are provided with slotted holes with the same size, the two slotted holes are symmetrically distributed by taking the central axis of each limiting hole (3) as a reference, the clamping blocks (4) are two and same in size, the clamping blocks (4) are movably clamped in the slotted holes of the clamping blocks, the outer sides of the clamping blocks (4) are movably connected with springs, and one sides of the springs, far away from the clamping blocks (4), are movably connected with the insides of the slotted holes;

the outer wall surface of carousel (7) is seted up the wave form channel of size unanimity, and its size and the size looks adaptation of carriage release lever (8), and carriage release lever (8) activity card is in its recess.

2. An auto-titration device for simultaneously conducting multiple sample tests according to claim 1, wherein: the movable rod (8) has two and the size is unanimous, and two holes that the size is the same are seted up to the inside of limiting plate (9), and its size and the size looks adaptation of movable rod (8), movable rod (8) fixed card in its hole and fixed connection in the both sides of clamp plate (10).

3. An auto-titration device for simultaneously conducting multiple sample tests according to claim 1, wherein: the size of the pressure plate (10) is larger than the spiral size formed by the limiting hole (3).

4. An auto-titration device for simultaneously conducting multiple sample tests according to claim 1, wherein: the hole has all been seted up to the inside of carousel (7), limiting plate (9) and clamp plate (10), and the size in carousel (7) hole and the size looks adaptation of bull stick (6), the size in limiting plate (9) and clamp plate (10) hole all is greater than the size of bull stick (6).

5. An auto-titration device for simultaneously conducting multiple sample tests according to claim 1, wherein: the bottom of the movable block (13) is movably connected with two springs with the same specification, the springs are symmetrically distributed by taking the central axis of the movable block (13) as a reference, and the bottoms of the springs are movably connected with the rack bar (18).

6. An auto-titration device for simultaneously conducting multiple sample tests according to claim 1, wherein: the size of gear (16) and the size looks adaptation of ratch (18), the channel has been seted up on the surface of ratch (18), its size and the size looks adaptation of movable block (17), movable block (17) activity card is in its channel, the via hole has been seted up to the inside of ratch (18), its size and the size looks adaptation of stock solution bottle (11), stock solution bottle (11) activity card is in its via hole.