CN110433186B - Application of artemisia stolonifera in preparation of moxibustion material - Google Patents

Application of artemisia stolonifera in preparation of moxibustion material Download PDF

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CN110433186B
CN110433186B CN201910948569.3A CN201910948569A CN110433186B CN 110433186 B CN110433186 B CN 110433186B CN 201910948569 A CN201910948569 A CN 201910948569A CN 110433186 B CN110433186 B CN 110433186B
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artemisia
leaf
moxibustion material
mugwort
leaves
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CN110433186A (en
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黄璐琦
黄璐明
刘大会
罗丹丹
张元�
康利平
袁媛
李斌
彭华胜
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Institute of Materia Medica of CAMS
Jiangxi University of Traditional Chinese Medicine
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Institute of Materia Medica of CAMS
Jiangxi University of Traditional Chinese Medicine
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A61H39/06—Devices for heating or cooling such points within cell-life limits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding

Abstract

The invention discloses an application of artemisia lata hance in preparation of a moxibustion material, and is characterized in that leaf velvet obtained after leaves of artemisia lata hance of artemisia of Compositae are sun-pressed and pestle-screened is used as the moxibustion material. Compared with the prior folium artemisiae argyi, the folium artemisiae argyi leaf has the advantages of more non-glandular hairs, high lint yield, less impurities of the leaf lint, softness, fineness, light smell, soft fire, high combustion value and strong permeability, has the outstanding advantages of wide raw material sources, low production cost and simple and easy production process, can replace the folium artemisiae argyi to produce high-quality moxibustion materials, and has wide application and development prospects.

Description

Application of artemisia stolonifera in preparation of moxibustion material
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to application of artemisia lasiocarpa in preparation of moxibustion materials.
Background
Moxibustion has a long application history in China, and the earliest existing medical prescription book 'fifty-two disease prescription' in China records two moxibustion treatment prescriptions. With the widespread use of acupuncture, moxibustion is also spread throughout the world.
The moxibustion material of traditional moxibustion is derived from Compositae plant folium Artemisiae Argyi (folium Artemisiae Argyi)Artemisia argyiLevl. et Van), and screening to remove impurities, and the obtained moxa is made and produced in many areas throughout the country. The four areas of origin of four famous artemisia argyi are recorded in the herb of artemisia argyi, which are named as bei, hai, chinese mugwort and qimaai, respectively. Besides the folium artemisiae argyi, whether better plants or materials are used for replacing traditional folium artemisiae argyi leaf moxa moxibustion materials is a problem which is always concerned by the industry, and other substitutes of the folium artemisiae argyi in the prior art are mainly proposed from the perspective of clinical application of the folium artemisiae argyi as a traditional Chinese medicine, but the substitute sources of the folium artemisiae argyi are not proposed from the perspective of whether the folium artemisiae argyi can be used as a moxibustion material.
Disclosure of Invention
The invention aims to provide application of artemisia lasiocarpa in preparation of moxibustion materials, and the artemisia lasiocarpa can replace artemisia leaves in the prior art.
An application of herba Artemisiae Ordosicae in preparing moxibustion material is prepared by screening folium Artemisiae Argyi of Compositae of Artemisia by sun pestle, wherein the folium Artemisiae Argyi is obtained by the following steps: collecting whole plant of Artemisia Spinosa, and drying in shade until water content is no more than 15%; picking off the leaves of the plants dried in the shade, and putting the leaves into a ceramic pounding medicine tank or a pure copper pounding medicine tank to be pounded; sieving the smashed powder with a 40-mesh sieve, and taking the leaf velvet left on the upper layer of the sieve surface.
Artemisia Spinosa (L.) Spreng of the inventionArtemisia stolonifera(maxim.) Komar is a perennial herb of Artemisia argyi L.of Artemisia of Compositae. Mainly produced in provinces such as Heilongjiang, Jilin, Liaoning, inner Mongolia, Hebei, Shanxi, Shandong, Jiangsu, Anhui, Zhejiang and Hubei, the leaf of the artemisia latifolia has dense non-glandular hairs, high lint yield after screening by a pestle in the sun, less impurities, softness, fineness and light smell of the leaf lint, and the fire of the novel moxibustion material prepared from the leaf lint is soft, the combustion value is high, and the permeation is lightThe moxa roll has strong force and better effect than folium artemisiae argyi, can be used as a new material for preparing moxibustion materials to replace folium artemisiae argyi leaves, has the outstanding advantages of wide raw material source, low production cost and simple and convenient production process, and has wide application and development prospect.
In addition, the application of the artemisia lasiocarpa in preparing the moxibustion material is also characterized by comprising the following technical characteristics:
wherein, the upper surface and the lower surface of the leaves of the artemisia stolonifera are covered with thick and dense non-glandular hairs.
Wherein the average lint ratio of the leaves of the artemisia stolonifera is 71.96 percent, and the thickness of the non-glandular hairs of the artemisia stolonifera is twice as thick as that of the non-glandular hairs of the Chinese mugwort.
Wherein the Artemisia latifolia leaf velvet contains eucalyptol which is the same volatile component as the Artemisia argyi leaf velvet.
The main chemical components of the leaf powder and leaf velvet of the wild artemisia leaf are consistent with that of Chinese mugwort, Qiai, Haimai and Beimugwort.
Wherein the total heat integral value of the moxibustion material is equal to or higher than the total heat integral value of the moxibustion material made of folium Artemisiae Argyi.
Drawings
The above and/or additional aspects and advantages of the present invention will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:
FIG. 1 is a photomicrograph of the upper surface of a leaf of the plant Artemisia apiacea, QICHUN, which is a base plant of the moxibustion material of example 1;
FIG. 2 is a photomicrograph of the lower surface of the leaf of the mugwort leaf in the form of Qi Chun, which is a plant based on the moxibustion material of example 1;
FIG. 3 is a photomicrograph of a cross-sectional view of a leaf of Artemisia sphaerocephala Hance of Umbelliferae of the original plant, namely, the material for moxibustion in example 1;
FIG. 4 is a photomicrograph of the upper surface of a Chinese mugwort sheet of the moxibustion material of example 1;
FIG. 5 is a photomicrograph of the lower surface of a leaf of Chinese mugwort as a moxibustion material in accordance with example 1;
FIG. 6 is a photomicrograph of a cross-sectional view of a leaf of Chinese mugwort as a moxibustion material in accordance with example 1;
FIG. 7 is a stereomicroscope photograph of the moxa of Artemisia ordosica in example 2, which is a source of the moxibustion material;
FIG. 8 is a photomicrograph of a folium Artemisiae Argyi velour of the original plant, QICHUNBANFYESHA, of the moxibustion material of example 2;
FIG. 9 is a photomicrograph of folium Artemisiae Argyi velour as a moxibustion material in this example 2;
FIG. 10 is a chromatogram for identifying a 3:1 leaf velvet thin layer made of the original plant of the folium Artemisiae Argyi of Qi Chun, in the example 3;
FIG. 11 is a LC-MS chromatogram of a leaf of Artemisia sphaerocephala Hayata, a plant based on the moxibustion material of example 4;
FIG. 12 is a LC-MS chromatogram of folium Artemisiae Argyi of the moxibustion material of this example 4;
FIG. 13 is a LC-MS chromatogram of 3:1 velour made of the original plant of the moxibustion material of this example 4, namely, QINCHUNDANYESHAN folium Artemisiae Argyi;
FIG. 14 is a LC-MS chromatogram of 3:1 leaf pile prepared from Chinese mugwort as a moxibustion material in this example 4;
FIG. 15 is a thermogravimetric analysis TG curve of 3:1 leaf velvet prepared from the original plant of the Material for moxibustion in example 5, namely, QINCHUNTANYESHAN (sic);
FIG. 16 is a DSC curve of differential scanning calorimetry of 3:1 velour made of the original plant of the moxibustion material of this example 5, namely, the plant of the root of the plant, namely, QINCHUNDAOYESHAN;
FIG. 17 is a thermogravimetric analysis TG curve of 3:1 leaf velvet prepared from Yuexi broadleaf artemisia scoparia as an original plant of the moxibustion material in the example 5;
FIG. 18 is a DSC curve of differential scanning calorimetry of 3:1 velvet manufactured by Yuexi broadleaf mountain wormwood, a basic plant of the moxibustion material in this example 5;
FIG. 19 is a thermogravimetric analysis TG curve of 3:1 leaf velvet prepared from the original plant of Haoshan broadleaf Artemisia scoparia in the moxibustion material of example 5;
FIG. 20 is a DSC curve of differential scanning calorimetry of 3:1 velvet manufactured from the original plant of Haoshan broadleaf Artemisia Haoshance in the moxibustion material of example 5;
FIG. 21 is a thermogravimetric analysis TG curve of 3:1 leaf pile made of Chinese mugwort as a moxibustion material in example 5;
FIG. 22 is a DSC curve of 3:1 DSC curve of folium Artemisiae Argyi in example 5.
Detailed Description
In order to make the objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. Several embodiments of the invention are presented in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
As introduced in the background art, aiming at the problem that the existing moxibustion material replaces and finds better moxibustion material than the existing folium artemisiae argyi leaves, the invention provides the application of the artemisia wideana leaves in the preparation of the moxibustion material, namely, the artemisia wideana leaves dried in the shade are put into a ceramic pounding tank or a pure copper pounding tank to be pounded, screened, and left on the upper layer of the screen surface to obtain the artemisia wideana leaves. In order to ensure the effect of the moxibustion material, the leaf velvet is usually screened several times by drying in a pestle so as to be beneficial to fully screening out impurities and promoting the leaf velvet to be soft and fine.
The existing moxibustion materials mainly comprise four famous Chinese mugwort, including northern Chinese mugwort, sea Chinese mugwort, Chinese mugwort and keemun mugwort. Moxa is an effective part of a moxibustion material, wherein the moxa yield, the burning value and the like of the moxa are important evaluation criteria of the quality of the moxa.
The effective component of the moxibustion material is leaf velvet obtained by screening leaves of artemisia sphaerocephala kuntze of artemisia of Compositae by drying in the sun and pestle, and the artemisia sphaerocephala kuntze is produced in the provinces of Qi spring county of Hubei province, Huoshan county of Anhui province and Yuexi county of Anhui province.
The production method of the moxibustion material comprises the following steps:
collecting the whole plant of the wide-leaf artemisia scoparia in each production area, and drying in the shade until the water content is not more than 15%;
picking off the leaves of the plants dried in the shade, and putting the leaves into a ceramic pounding medicine tank or a pure copper pounding medicine tank to be pounded;
sieving the pulverized powder with 40 mesh sieve, and collecting the leaf velvet left on the upper layer of the sieve surface.
In order to evaluate the quality condition of the moxibustion material, the moxibustion material from different sources is compared and verified through 5 examples, and the experiments comprise an apparent morphology identification experiment, a fluff yield experiment, thin layer identification, a chemical composition detection experiment, thermogravimetric analysis and differential thermal analysis.
Example 1:
apparent morphology identification experiment: comparison of leaf thickness of leaf pulp and non-glandular hair of leaf cross section of wild Artemisia Spinosa and Artemisia Hayata, Artemisia princeps, and Artemisia argyi
The basic plant of the moxa material used in the invention is the broadleaf artemisia scoparia which is short and small, has thin stem, dark green leaf surface and thicker and whiter villi on the back of the leaf compared with the four famous artemisia leaves.
Taking the upper surface, the lower surface and the cross section of the leaves of the five moxibustion material basic plants respectively to prepare microscopic slices, and taking pictures for observation and measurement. As shown in FIGS. 1-6, microphotographs of the upper surface, lower surface and cross section of a conventional folium Artemisiae Argyi tablet are compared with those of a folium Artemisiae Argyi tablet. The observation shows that the artemisia stolonifera has more and compact non-glandular hairs on the upper and lower epidermis and thicker mesophyll and non-glandular hairs compared with the artemisia stolonifera.
As shown in Table 1, in the actual measurement, the thickness (T) of the leaf pulp of mugwort leaf as the basic material of the moxibustion material used in the present invention and the conventional mugwort, mugwort and mugwort1) And non-glandular hair thickness (T)2) In comparison, the thickness of the mesophyll is in the order of artemisia stolonifera>Sea wormwood>Artemisia princeps Pampanini>Chinese mugwort; from the thickness of non-glandular hair to the width of artemisia stolonifera>Artemisia princeps Pampanini>Chinese mugwort>Sea wormwood. Wherein the average values of the non-glandular hair thickness of mugwort broadleaf in the three places of the county of Qi Chun, the county of Hui province and the county of Yuexi, Anhui province are respectively 2.21 times, 2.05 times and 2.37 times of the average value of the non-glandular hair thickness of mugwort, whereby it can be inferred that the non-glandular hair of mugwort broadleaf is one time thicker than the non-glandular hair of mugwort.
TABLE 1 comparison of leaf meat and non-glandular hair thickness of leaf cross sections of Artemisia latifolia and Artemisia maritima, Artemisia beiyi, and Artemisia argyi
Example 2:
pile-out rate test: the fluff yield of folium Artemisiae Argyi, QI, HAI, BEI, and QI folium Artemisiae Argyi is compared
40g (M) of dry leaves of mugwort broadleaf as a basic plant of the moxa material used in the invention and traditional mugwort, wormwood, and wormwood are weighed respectively, the dry leaves are beaten for 2min by a pulverizer, 200 times of a sieve with No. 1 (40 meshes) is used according to a certain direction, velvet is separated from powder, the net velvet weight (M) is weighed, the velvet rate (M/M) is calculated, and the results are shown in FIGS. 7-9 and Table 2, comparison between the velvet rate and the results shown in Table 2 shows that the content of the mesophyll tissue in the mugwort leafy velvet is less than that of the mesophyll tissue in the mugwort leafy velvet, the average velvet rate of the mugwort leafy velvet is 71.96% according to the data in Table 2, the velvet rate of the mugwort produced in spring county of Hubei province, Huohan province county of Anhui province, and West county of Anhui province is higher than that the mugwort produced in Yue county of Anhui province, the Moxie is higher than that the mugwort, the moxa yield of the traditional mugwort leafy is higher than 3927.27%, the moxa yield of the mugwort leafy, the moxa yield of the northern mugwort, 3614.36% of the moxa yield of the traditional mugwort, 3614% of the mugwort leafy, 3614% of the mugwort with the mugwort leafy moxa production.
TABLE 2 data table of the lint yield of leaves of wild mugwort, keemun mugwort, northern mugwort, seamugwort and mugwort
Figure DEST_PATH_IMAGE002
Example 3:
the artemisia latifolia leaf velvet is further screened to be made into 3:1 velvet, and then thin-layer identification is carried out according to the method under the item of the clear moxa stick [ identification ] in the ministry standard, and the result is shown in figure 10. In the chromatogram of the test sample and the mixed chromatogram of the test sample and the eucalyptol, spots with the same color appear at the corresponding positions of the chromatogram of the reference eucalyptol, so that the result can preliminarily determine that the artemisia lasiocarpa contains chemical components similar to those in the folium artemisiae argyi.
Example 4:
chemical component detection experiment: LC-MS fingerprint comparison of folium Artemisiae Argyi, QI folium Artemisiae Argyi, HAI folium Artemisiae Argyi, North folium Artemisiae Argyi, and folium Artemisiae Argyi
Taking 100mg of sample 60% ethanol for ultrasonic extraction for 1h, centrifuging the extract for 10 minutes at 1 ten thousand revolutions, and filtering the extract by a 0.22 mu m filter membrane to be used as a sample to be analyzed. Ultra-high performance liquid phase: waters acquisition I Class UPLC system, column: waters ACQUITYBEH C18 ultra high performance liquid chromatography column (2.1X 100 mm, 1.8 μm); mass Spectrometry System Waters Zevo-G2-S Q TOF (Waters Corp., USA), ionization mode: and (4) carrying out electrospray on negative ions.
From the content of each chemical component in the result, all samples contain chlorogenic acid, cryptochlorogenic acid, schaftoside, isochlorogenic acid B, isochlorogenic acid A, isochlorogenic acid C and the like, the content of chlorogenic acid components is higher than that of flavonoid components, and the content of isochlorogenic acid A is the highest. After the velvet is prepared, the contents of chlorogenic acid and flavonoid components are multiplied, but the accumulation of flavonoid components in the artemisia lasiocarpa is less. The folium artemisiae argyi contains more abundant components than the folium artemisiae argyi, and the folium artemisiae argyi has less different components than the folium artemisiae argyi; analysis of the different samples of the produced fleece revealed similar results. This indicates that the two contain similar chemical components.
TABLE 3 content of 10 index components (unit: mg/g) in Artemisia sphaerocephala, Artemisia argyi and Argy Wormwood in different producing areas
Figure DEST_PATH_IMAGE003
As shown in FIGS. 11-14, the moxibustion material folium Artemisiae Argyi used in the present invention has little difference in chemical components of LC-MS fingerprint spectra of traditional folium Artemisiae Argyi.
Example 5:
thermogravimetric and differential thermal analysis experiments: thermogravimetric analysis and differential thermal analysis comparison of folium Artemisiae Argyi, QIAI, folium Artemisiae Argyi, North folium Artemisiae Argyi, and folium Artemisiae Argyi
As shown in FIGS. 15-22, thermogravimetric analysis of 3:1 leaf velvet prepared from folium Artemisiae Argyi (three places of origin, QICHUN, Yuexi, and HUO SHAN) and conventional folium Artemisiae Argyi (Mettler TO Switzerland)The thermogravimetric analyzer of LEDO company is used for measurement and analysis, oxygen is selected as carrier gas, programmed heating scanning is carried out, the temperature range of an experiment is set to be 30-900 ℃, the heating rate is 10 ℃/min, the air flow rate is 100mL/min, and Al2O3The empty crucible is used as a control, the sample dosage is about 7.5 mg), taking a thermal analysis diagram of the holyash broad-leaf mountain wormwood as an example, the whole DTG curve can be divided into four zones (I, II, III and IV zones) of three stages (a drying weight loss stage in the zone I, a combustion oxidation carbonization stage in the zones II and III and a burn-out ash stage in the zone IV), wherein the first stage is a devolatilization weight loss drying zone which occurs at 30 ~ 137 ℃ and has a mass loss of 8.76%, the second stage comprises a combustion oxidation zone in the zone II (137.0-367.0 ℃) and a carbonization zone in the zone III (367.0-442.0 ℃) and has a mass loss of 87.09% of the total mass loss, which is equivalent to the contents of holocellulose and lignin in a moxa sample, the mass of the residual ash in the zone IV (442-367.0 ℃) is 2.23%, which can be defined as a burn-out ash zone, and the total integral value of heat is 8760 mJ/mg.
As shown in Table 4, when the 3: 1-leaf fine hair made of the original plant Artemisia sphaerocephala and the traditional Chinese mugwort and mugwort leaves used as the moxibustion material are weighed and compared by differential thermal analysis, the total heat integral value of the four-leaf fine hair made of the Artemisia sphaerocephala is 0.01% ~ 8.36.36% higher than that of the northern moxa, 11.89% ~ 21.23.23% higher than that of the Japanese moxa, 8.22% ~ 17.25.25% higher than that of the Qiai and 7.53% ~ 16.50.50% higher than that of the Chinese mugwort, therefore, the total heat integral value of the four-leaf fine hair made of the Artemisia sphaerocephala is 0.01% ~ 21.23.23% higher than that of the traditional four-leaf moxa.
TABLE 4 differential thermal analysis table for moxa of moxibustion material
Figure DEST_PATH_IMAGE004
The above experimental results show that: apparent morphological identification experiment shows that the thickness order of non-glandular hairs is artemisia scoparia>Artemisia princeps Pampanini>Chinese mugwort>Artemisia princeps Pampanini, T of Artemisia princeps Pampanini2/（T1+T2) The average value is obviously larger than that of Chinese mugwort and sea mugwort; the fluff yield is that of the artemisia scoparia>Artemisia princeps Pampanini>Sea wormwood>Qiai>Chinese mugwort, wherein the average lint yield of the broad-leaved Chinese mugwort is significantly higher than that of the northern Chinese mugwort, the sea mugwort, the Qiai and the Chinese mugwort; the results of thin-layer experiments show that the artemisia lasiocarpa in different producing areas all contain eucalyptol and meet the thin-layer identification requirements of the moxa sticks; the LC-MS fingerprint results show that the main effective chemical components of the artemisia lasiocarpa are similar to the main chemical components of the four artemisia lasiocarpa; the total heat integral value of the burnt Artemisia latifolia leaf velvet is significantly higher than that of the traditional four-famous moxa, especially than that of the sea moxa, the Qiai moxa and the Chinese mugwort. Therefore, the average fluff yield and the average total heat of combustion of the artemisia stolonifera are better than those of four moxa, and the effective components are similar, so that the application provides a better raw material source for moxibustion materials by using the artemisia stolonifera as the moxibustion materials.
In conclusion, according to the moxibustion material provided by the invention, leaves of artemisia lasiocarpa have dense non-glandular hairs, the lint yield is high after screening by a pestle, the impurities of the leaf velvet are few, the leaf velvet is soft and exquisite, the smell is light, the firepower of the novel moxibustion material prepared from the leaf velvet is soft, the combustion value is high, the permeability is strong, the effect is superior to that of artemisia argyi, the novel moxibustion material can be used as a new material for preparing the moxibustion material to replace the artemisia argyi leaves, and the novel moxibustion material has the outstanding advantages of wide raw material source, low production cost and simple and convenient production process, and has wide application and development prospects.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (6)

1. An application of artemisia lata hance in preparation of moxibustion material is characterized in that leaf velvet obtained by screening leaves of artemisia lata hance of artemisia of Compositae in a sun pestle is used as the moxibustion material, wherein the leaf velvet is obtained through the following steps: collecting whole plant of Artemisia Spinosa, and drying in shade until water content is no more than 15%; picking off the leaves of the plants dried in the shade, and putting the leaves into a ceramic pounding medicine tank or a pure copper pounding medicine tank to be pounded; sieving the smashed powder with a 40-mesh sieve, and taking the leaf velvet left on the upper layer of the sieve surface.
2. The use of Artemisia latifolia as claimed in claim 1, wherein the upper and lower surfaces of the leaves of Artemisia latifolia are covered with thick and dense non-glandular hair.
3. The use of Artemisia lasiocarpa leaf in the preparation of moxibustion material as claimed in claim 1, wherein the average lint ratio of the leaves is 71.96%, and the thickness of non-glandular hairs is twice as thick as that of non-glandular hairs of Artemisia argyi.
4. The use of Artemisia latifolia as claimed in claim 1, wherein the Artemisia latifolia leaf fluff contains eucalyptol which is the same volatile component as the moxa.
5. The use of the artemisia lasiocarpa as claimed in claim 1, wherein the main chemical components of the powder and the fine powder of the artemisia lasiocarpa leaf are compatible with mugwort, mugwort and mugwort.
6. The use of Artemisia sphaerocephala Hance in the preparation of moxibustion material as claimed in claim 1, wherein the total heat integral value of burning of the moxibustion material is equal to or higher than that of moxibustion material prepared from folium Artemisiae Argyi.
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