CN110398594A - A kind of blood sample automatic mixing device and blood cell analysis equipment - Google Patents

A kind of blood sample automatic mixing device and blood cell analysis equipment Download PDF

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Publication number
CN110398594A
CN110398594A CN201910324795.4A CN201910324795A CN110398594A CN 110398594 A CN110398594 A CN 110398594A CN 201910324795 A CN201910324795 A CN 201910324795A CN 110398594 A CN110398594 A CN 110398594A
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CN
China
Prior art keywords
test tube
support
blood sample
mixing device
automatic mixing
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Pending
Application number
CN201910324795.4A
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Chinese (zh)
Inventor
于记良
邹云平
陆锋
翟留伟
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Shenzhen Dymind Biotechnology Co Ltd
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Shenzhen Dymind Biotechnology Co Ltd
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Publication of CN110398594A publication Critical patent/CN110398594A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements

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  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses a kind of blood sample automatic mixing device and blood cell analysis equipment, the blood sample automatic mixing device includes first support, second support and flexible column, the second support is fastened on above the first support by the flexible column, and rotary swing and vibration can be carried out relative to the first support, part of the flexible column between the first support and the second support is arranged in hourglass shape.Blood sample automatic mixing device of the present invention and blood cell analysis equipment can mix well automatically micro-example, be not necessarily to artificial treatment, and save manpower and time cost, improve the working efficiency that micro-example mixes.

Description

A kind of blood sample automatic mixing device and blood cell analysis equipment
Technical field
The invention belongs to blood cell analysis technical fields, it is more particularly related to which a kind of blood sample automatic mixing fills It sets and blood cell analysis equipment.
Background technique
There are two types of Blood collections for blood routine detection at present: acquisition venous blood and acquisition peripheral blood.Wherein, venous blood blood sampling volume Greatly, it is milliliter (ml) rank, is suitable for the convenient patient of the blood samplings such as adult;And peripheral blood blood sampling volume is small, at 100 microlitres (ul) Up and down, it is suitable for the patient that it is inconvenient that children etc. take a blood sample.For the opposite venous blood sample size of peripheral blood sample size, sample Amount is very little, and the two is not the same order of magnitude.And the type with machine automatization evenly mixing device on current cellanalyzer, for examination Mainly simulate artificial test tube is mixed by inversion method or swing rotary to the implementation method that sample in pipe is mixed back and forth, i.e., Certain point vertical line is implemented to swing on test tube central axis or its extended line, but above-mentioned machine automatization mixes method and is only applicable to vein The mixing of blood sample cannot reach the requirement to peripheral blood sample blending micro in test tube of blood routine detection, not be suitable for trying The mixing of tip blood sample in managing.When carrying out analysis detection to tip blood sample, mostly uses manually rock peripheral blood greatly Test tube is mixed, and working efficiency is low, and sample blending is inconvenient.
Therefore, it is necessary to propose a kind of automatic mixing device mixed suitable for micro-blood sample.
Summary of the invention
The present invention is directed to solve the above-mentioned problems of the prior art to a certain extent, a kind of blood sample automatic mixing dress is provided It sets and method, in order to mix well automatically to micro-blood sample, is not necessarily to artificial treatment, save manpower and time cost, mentions The working efficiency that high micro-blood sample mixes.
For this purpose, the embodiment of the present invention provides a kind of blood sample automatic mixing device, the blood sample automatic mixing device includes the One bracket, second support and flexible column, the second support are fastened on above the first support by the flexible column, And rotary swing and vibration can be carried out relative to the first support, the flexible column be located at the first support and described Part between second support is arranged in hourglass shape.
In one embodiment, the blood sample automatic mixing device further includes the first driving unit and eccentric block, and described One driving unit is arranged in the second support, and the eccentric block is fixed on the first driving unit output shaft end, described Eccentric block executes rotation under first driving unit driving, around the first driving unit axis, drives the second support Rotary swing and vibration are carried out relative to the first support, and then the test tube for driving support to be fixed on the second support is same Step carries out rotary swing and vibration.
In one embodiment, the blood sample automatic mixing device further includes third bracket and test tube storehouse, and described first Frame is connected with third bracket by support rod, and the test tube storehouse is arranged on the third bracket.
In one embodiment, test tube pallet is provided in the second support, the test tube pallet is equipped with inner sunken face, The inner sunken face is used to support the bottom of test tube so that test tube to be contained in the test tube storehouse.
In one embodiment, the first groove and the second groove are set in the second support, the support rod A part is arranged in first groove, and the flexible module is flexible column, and a part of the flexible column is located at described In second groove.
In one embodiment, third groove is opened up in the side portion of the second support, which is one The arc-shaped structure of side opening;The quantity of the support rod is two, and a part of one of support rod is set to described the In one groove, a part of another support rod is set in the third groove.
In one embodiment, the test tube storehouse includes hollow shaft sleeve, and the hollow shaft is set on the third bracket Top, the position that the third bracket corresponds to the hollow shaft sleeve offer through-hole, the hollow shaft sleeve and the through-hole for holding Test tube is received to constrain test tube moving position.
In one embodiment, the flexible column is made of rubber or silica gel material, or is spring.
In one embodiment, the side of the second support is provided with concave station, and it is empty that described second is arranged on the concave station Heart slot, the flexible column include top column cap and cylinder, and the top column cap is set on the concave station surface, and the cylinder is set It is placed in second groove.
In one embodiment, the cross section of the top column cap is circular configuration, and the cylinder is cylindrical structure, described The diameter of the circular configuration cross section of top column cap is greater than the diameter of the cylindrical structure of the cylinder, and the flexible column includes lower part Column cap, the lower part column cap lower section are provided with connector, are provided with connecting hole in the first support, which is arranged in institute It states in connecting hole so that flexible column to be fixed in the first support.
Compared with prior art, implement blood sample automatic mixing device of the present invention to have the advantages that in the first driving Under unit driving, fixed eccentric block executes rotation around the first driving unit axis on the first driving unit output shaft end, due to solid There is the vibration module of the first driving unit to be fastened on first support top and eccentric block rotary shaft by flexible module surely Hole drives the rotary swing of the vibration module and vibration when eccentric block rotation not in its center of gravity, due to equipped with wait mix The blood specimen collection test tube of sample is arranged on the test tube pallet of second support, and the swing and vibration of vibration module will drive test tube support Test tube on disk does rotary swing and vibration, to realize the purpose of automatic mixing sample, be not necessarily to artificial treatment, save manpower and Time cost improves the working efficiency that micro-blood sample mixes;And blood sample automatic mixing device structure provided by the invention is more simple It is single compact, be conducive to instrument miniaturization.
As same inventive concept, according to second aspect, the embodiment of the present invention also provides a kind of blood cell analysis equipment, Including a kind of mentioned-above blood sample automatic mixing device, the blood cell analysis equipment further includes auto-feeder, described Auto-feeder includes pedestal and transmission component, and the second driving unit is fixed on the pedestal, and the transmission component is removable It is arranged dynamicly on the base, the transmission component connects the first support, and second driving unit drives the transmission group Part is mobile relative to the pedestal, and the transmission component drives the first support mobile the test tube storehouse is moved to reception The ready position of blood specimen collection test tube.
In one embodiment, the transmission component includes sliding shoe, slide rail, fixed block, mobile push plate and sliding Leading screw and nut mechanism, the slide rail are fixed on the pedestal, and the sliding block is set in the slide rail;The cunning Dynamic leading screw and nut mechanism is connect with second driving unit and mobile push plate respectively;The fixed block respectively with described first Frame is connected with the sliding block;The mobile push plate pushes fixed block and sliding block mobile under the action of sliding screw nut body, The sliding block is moved along the slide rail to guide fixed block moving direction.
In one embodiment, it is fixed in the mobile push plate and blocks optocoupler baffle, detection is provided on the pedestal Optocoupler, the detection optocoupler and blocks optocoupler baffle and cooperates shift position to detect the mobile push plate.
In one embodiment, the blood cell analysis equipment further includes test tube clamping jaw, the test tube clamping jaw be used for together with The micro peripheral blood acquisition test tube picked up first carries out lowering action, and falling head is horizontal for the touching of test tube bottom or close to second On bracket in the fixed rubber test tube support with inner sunken face, then test tube clamping jaw executes horizontal feed away from rack for test tube Direction moves to horizontal ready bit, so that test tube clamping jaw is kept completely separate with by folder test tube.
Compared with prior art, implement blood cell analysis equipment of the invention to have the advantages that
The invention discloses a kind of blood cell analysis equipment comprising auto-feeder and blood sample automatic mixing device. Firstly, the auto-feeder includes pedestal and transmission component, the second driving unit drives transmission component movement, using described The movement of transmission component drives the first support mobile, since test tube storehouse is arranged on third bracket, can be whereby The test tube storehouse is moved to the ready position for receiving blood specimen collection test tube, realizes the auto-feed of blood specimen collection pipe.Secondly, In Under the driving of first driving unit, fixed eccentric block executes around the first driving unit axis and turns on the first driving unit output shaft end Dynamic, the vibration module due to fixing the first driving unit is fastened on above first support by flexible module, and eccentric Block rotary shaft hole drives the rotary swing of the vibration module and vibration when eccentric block rotation not in its center of gravity, due to dress The blood specimen collection test tube for needing to be mixed sample is arranged on the test tube pallet of first support, and the swing and vibration of vibration module can bands Test tube on dynamic test tube pallet does rotary swing and vibration, to realize the purpose of automatic mixing sample, is not necessarily to artificial treatment, section Human-saving and time cost improve the working efficiency that micro-blood sample mixes.
To enable the above objects, features and advantages of the present invention to be clearer and more comprehensible, better embodiment is cited below particularly, and match Appended attached drawing is closed, is described in detail below.
Detailed description of the invention
It, below will be to use required in embodiment in order to illustrate more clearly of the technical solution of embodiment of the present invention Attached drawing be briefly described, it should be understood that the following drawings illustrates only certain embodiments of the invention, therefore should not be seen Work is the restriction to range, for those of ordinary skill in the art, without creative efforts, can be with Other relevant attached drawings are obtained according to these attached drawings.
Fig. 1 is the structural schematic diagram of blood sample automatic mixing device described in the embodiment of the present invention;
Fig. 2 is that test tube storehouse described in the embodiment of the present invention is moved to the schematic diagram for receiving the ready position of test tube to be mixed.
In figure, first support 1, second support 2, third bracket 3, eccentric block 4, shock structure 5, first motor 6, test tube pallet 7, the first groove 8, the second groove 9, test tube storehouse 10, support rod 11, concave station 12, top column cap 13, cylinder 14, third is hollow Silk is slided in slot 15, test tube 16, pedestal 17, the second motor 18, sliding shoe 19, slide rail 20, fixed block 21, mobile push plate 22 Optocoupler baffle 24 is blocked in stem nut mechanism 23, detects optocoupler 25, test tube clamping jaw 26.
Specific embodiment
Below in conjunction with attached drawing in embodiment of the present invention, to the technical solution in embodiment of the present invention carry out it is clear, It is fully described by, it is clear that described embodiment is only some embodiments of the invention, rather than whole embodiment party Formula.The component of the embodiment of the present invention being usually described and illustrated herein in the accompanying drawings can be arranged with a variety of different configurations And design.Therefore, requirement is not intended to limit to the detailed description of the embodiments of the present invention provided in the accompanying drawings below to protect The scope of the present invention of shield, but it is merely representative of selected embodiment of the invention.Based on embodiments of the present invention, this field Technical staff's every other embodiment obtained without making creative work, belongs to protection of the present invention Range.
In the description of the present invention, it should be noted that term " center ", "upper", "lower", "left", "right", " vertical ", The orientation or positional relationship of the instructions such as "inner", "outside" is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of retouching It states the present invention and simplifies description, rather than the device or element of indication or suggestion meaning must have a particular orientation, with specific Orientation construction and operation, therefore be not considered as limiting the invention.In addition, term " first ", " second ", " third " are only For descriptive purposes, it is not understood to indicate or imply relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected;It can To be mechanical connection, it is also possible to be electrically connected;It can be directly connected, can also can be indirectly connected through an intermediary Connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood at this with concrete condition Concrete meaning in invention.
As shown in Figure 1, can be used for Trace Blood sample the embodiment of the invention provides a kind of blood sample automatic mixing device Mixing, such as the mixing of tip blood sample.Specifically, the blood sample automatic mixing device includes ontology and vibration module, institute Ontology is stated equipped with test tube storehouse, the vibration module includes the first driving unit, eccentric block and test tube supporting module, and described first Driving unit, eccentric block and test tube supporting module are sequentially connected, and the test tube supporting module is for supporting blood specimen collection test tube So that blood specimen collection test tube is contained in the test tube storehouse, first driving unit drives the eccentric block rotation to drive for bottom Pendulum motion is done in the bottom of the test tube supporting module and the blood specimen collection test tube, to mix the invisible spectro blood of blood specimen collection Sample.According to above description and the record of Fig. 1, it is known that the eccentric block, ontology, vibration module are and are contained in the examination The blood specimen collection test tube linkage of Guan Cangzhong, the eccentric block drives lower progress eccentric motion by the first driving unit, can band The bottom movement of blood specimen collection test tube in dynamic test tube storehouse, the top of blood specimen collection test tube are located in test tube storehouse, can be in test tube It is moved in storehouse, the automatic mixing of sample in test tube is realized with this.
Blood sample automatic mixing device of the embodiment of the present invention, under the driving of the first driving unit, the first driving unit output shaft Fixed eccentric block executes rotation around the first driving unit axis on end, and the vibration module due to fixing the first driving unit connects solid It is scheduled on above ontology and eccentric block rotary shaft hole is not in its center of gravity, therefore drive the vibration module to return when eccentric block rotation Rotatable swing and vibration vibrate mould since the blood specimen collection test tube equipped with sample to be mixed is arranged on the test tube pallet of ontology The swing and vibration of block will drive the test tube on test tube pallet and do rotary swing and vibration, to realize the mesh of automatic mixing sample , it is not necessarily to artificial treatment, save manpower and time cost, improves the working efficiency that micro-blood sample mixes.
Further, in certain embodiments, the vibration module further includes flexible module, and described flexible module one end is set It sets in the test tube supporting module, the other end is fixed on the body.
Flexible module is fabricated from a flexible material in the embodiment of the present invention, and the setting of the flexible module is to make test tube branch Hold mode block preferably carries out rotary swing, so that blood specimen collection test tube be driven to be swung, realization is mixed well.
In certain embodiments, the ontology includes first support and third bracket, and the test tube supporting module includes the Two brackets, the first support and third bracket are connected by support rod;Third bracket to be fixed in the first support; The eccentric block is arranged in the first support, and the first driving unit setting is on the secondary support bracket;The flexible module One end connects the first support, and the other end connects the second support;The test tube storehouse is arranged on the third bracket.It is excellent Selection of land, the second support is between the first support and third bracket.
In the embodiment of the present invention, the first support can turn under the action of eccentric block and the first driving unit around motor Axis does eccentric motion, and then drives the second support to carry out relative to the first support and third bracket by flexible module Rotary swing, at this point, second support is carrying out rotary swing since test tube support is fixed in the second support When, it will drive test tube and synchronize and do rotary swing, realize mixing well for blood sample in test tube.
In certain embodiments, test tube pallet is provided in the second support, the test tube pallet is equipped with inner sunken face, The inner sunken face is used to support the bottom of test tube so that test tube to be contained in the test tube storehouse.
Inner sunken face described in the present embodiment forms a cavity, and one of the bottom of the test tube equipped with sample to be mixed Set up separately and set in the cavity so that test tube is held, test tube pallet and test tube storehouse cooperation with will sample be mixed test tube It is fixed on the blood sample automatic mixing device, when mixing operation, it is rotary that the test tube support disk drives the bottom of test tube to do It swings and vibrates, mix well invisible spectro blood sample to realize.
In certain embodiments, the first groove and the second groove are set in the second support, the support rod A part is arranged in first groove, and the flexible module is flexible column, and a part of the flexible column is located at described In second groove.And first groove should have enough spaces so that support rod can be in first groove Activity;A part of the flexible column is located in second groove, described in the first driving unit output axis connection partially Heart block.
In the present embodiment, according to above description and the record of Fig. 1, it is known that the eccentric block, flexible module, second Bracket, test tube pallet are linked with the test tube being contained in the test tube storehouse, and the eccentric block turns around the axis of the first driving unit Moving can drive the test tube in test tube storehouse to do the rotary automatic mixing for swinging and realizing sample in test tube while doing eccentric motion.
Specifically, the present embodiment is placed in the examination when carrying out blood sample mixed well, by the test tube equipped with blood sample to be mixed The bottom of Guan Cangzhong, test tube are lived by the test tube support pan arrest, therefore test tube can be limited in the test tube storehouse, and test tube storehouse should have There are enough spaces, so that test tube can move in test tube storehouse when carrying out mixing operation.It is driven in the first driving unit Under, fixed eccentric block executes rotation around the first driving unit axis on the first driving unit output shaft end, due to fixing the first drive The second support of moving cell is fastened on above first support by flexible column and eccentric block rotary shaft hole is not in its center of gravity On, therefore the rotary swing of the second support and vibration are driven when eccentric block rotation, since the test tube equipped with sample to be mixed is set It sets on the test tube pallet of second support, the swing and vibration of second support will drive the test tube on test tube pallet and do rotary pendulum Dynamic and vibration is not necessarily to artificial treatment to realize the purpose of automatic mixing sample, and save manpower and time cost, improves Trace Blood The working efficiency that sample mixes.
Preferably, first driving unit is preferably but not limited to be DC brushless motor, and the DC brushless motor is by one Controller control driving, it should be noted that be also an option that according to technical experience first driving unit as other It is capable of providing the mechanism of driving force, exhaustion is not carried out to the specific type selecting of the first driving unit in the embodiment of the present invention.
Preferably, the test tube pallet is preferably but not limited to be made of the flexible materials such as rubber or silica gel, brush DC electricity Machine executes driving certain time, and eccentric block is rotated around motor shaft therewith, and then second horizontal bracket is driven to produce Raw rotary swing and vibration;Fall in the micro end in the rubber test tube support with inner sunken face fixed on the second horizontal bracket Tip blood acquires test tube, and bottom generates rotary swing and vibration with the second horizontal bracket and test tube storehouse is opposing stationary to micro- Peripheral blood acquisition test tube pipe shaft constraint is measured, micro peripheral blood acquisition test tube bottom swings larger relatively;To which micro peripheral blood is adopted Blood sample reaches blood sample mixed well purpose in centrifugation whipping and the multiple influence of vibration in conjunction under in collection test tube, while preventing broken blood thin Born of the same parents.
In one embodiment, first groove is circle, is arranged in the support rod in first groove A part be cylinder, and the diameter of round first groove is greater than the body diameter.Bias described in the embodiment of the present invention Block drives the rotary swing of the second support and vibration, the design of cylinder and round first groove, so that second when rotating Bracket can do rotary swing and vibration relative to the third bracket, be further driven to test tube and do rotary swing and vibration It is dynamic.
In one embodiment, the side of the second support is provided with concave station, and it is empty that described second is arranged on the concave station Heart slot;The flexible column includes top column cap and cylinder, and the top column cap is set on the concave station surface, and the cylinder is set It is placed in second groove.The cross section of the top column cap of the flexible body and second groove is round knot Structure, cylinder are cylindrical structure, and the diameter of the circular configuration cross section of the top column cap of the flexible body is greater than the straight of the cylindrical structure The circular configuration cross-sectional diameter of diameter and second groove, and the flexible body selects flexible material to be made, such as rubber Or silica gel material, or spring, so that second support can be swung relative to the third bracket and first support Movement.
In one embodiment, the flexible column includes lower part column cap, is provided with connector below the lower part column cap, institute It states and is provided with connecting hole in first support, which is arranged in the connecting hole so that flexible column is fixed on described first On frame.And the lower part column cap of the flexible body be circular configuration, the circular configuration cross section of the lower part column cap of the flexible body it is straight Diameter is greater than the diameter of the cylindrical structure and the circular configuration cross-sectional diameter of second groove.
In one embodiment, third groove is opened up in the side portion of the second support, which is one The arc-shaped structure of side opening;The quantity of the support rod is two, and a part of one of support rod is set to described the In one groove, a part of another support rod is set in the third groove, wherein another support rod A part be cylindrical structure so that second support can be done relative to the third bracket and first support it is rotary swing and Vibration.
In one embodiment, the test tube storehouse includes hollow shaft sleeve, and the hollow shaft is set on the third bracket Top, the third bracket offer through-hole, the hollow shaft sleeve and through-hole coaxial arrangement, the hollow shaft sleeve and the through-hole Perforation part formed a test tube accommodation space.For the embodiment of the present invention when implementing, examination is stated in test tube support pan arrest residence Pipe, the test tube accommodation space, in order to which test tube to be fixed, allow to try for accommodating test tube to constrain test tube moving position Pipe carries out rotary swing.
According to second aspect, another embodiment of the present invention provides a kind of blood cell analysis equipment comprising noted earlier A kind of blood sample automatic mixing device, the blood cell analysis equipment further includes auto-feeder, the auto-feeder Including pedestal and transmission component, the second driving unit is fixed on the pedestal, the transmission component is movably disposed at base On seat, the transmission component connects the ontology, and second driving unit drives the transmission component relative to the pedestal Mobile, the transmission component drives the ontology mobile so that the test tube storehouse to be moved to the preparation position for receiving blood specimen collection test tube It sets.
A kind of blood cell analysis equipment of the embodiment of the present invention comprising auto-feeder and blood sample automatic mixing dress It sets.Firstly, the auto-feeder includes pedestal and transmission component, the second driving unit drives transmission component movement, utilizes The movement of the transmission component drives the ontology mobile, on the body due to the setting of test tube storehouse, can be whereby by institute It states test tube storehouse and is moved to the ready position for receiving blood specimen collection test tube, realize the auto-feed of blood specimen collection pipe.Secondly, first Under driving unit driving, fixed eccentric block executes rotation around the first driving unit axis on the first driving unit output shaft end, by It is fastened on above ontology by flexible module and eccentric block rotary shaft hole in the vibration module for fixing the first driving unit Not in its center of gravity, therefore the rotary swing of the vibration module and vibration are driven when eccentric block rotation, due to being equipped with sample to be mixed The blood specimen collection test tube of product is arranged on the test tube pallet of ontology, and the swing and vibration of vibration module will drive on test tube pallet Test tube does rotary swing and vibration, to realize the purpose of automatic mixing sample, is not necessarily to artificial treatment, saves manpower and time into This, improves the working efficiency that micro-blood sample mixes.
Further, second driving unit is preferably motor.In one embodiment, described device further includes pedestal And transmission component, the second motor is fixed on the pedestal, and second motor is electrically connected with the controller, and by controller control System, the transmission component are movably disposed on pedestal, and the transmission component connects the first support, second motor The transmission component is driven to move relative to the pedestal, the transmission component drives first support and third bracket mobile to incite somebody to action The test tube storehouse is moved to the ready position for receiving test tube to be mixed, and the ready position is as shown in Figure 2.
In one embodiment, the transmission component includes sliding shoe, slide rail, fixed block, mobile push plate and sliding Leading screw and nut mechanism, the slide rail are fixed on the pedestal, and the sliding block is set in the slide rail;The cunning Dynamic leading screw and nut mechanism is connect with second motor and mobile push plate respectively;The fixed block respectively with the ontology first Bracket is fixedly connected with the sliding block;The slide rail is arranged in the aperture at the middle part of the mobile push plate, and the shifting Dynamic push plate supports the fixed block, and the mobile push plate can be fixedly connected or be not fixed with the fixed block and connect, described Mobile push plate pushes fixed block and sliding block mobile under the action of sliding screw nut body, and the sliding block is along the slide rail It is mobile that guide fixed block moving direction, sliding block and slide rail play the guiding role herein so that evenly mixing device can by into It is given to target position.Wherein, the propulsive mechanism that sliding screw nut body is well known to those skilled in the art, therefore herein not Its specific structure is illustrated.
In one embodiment, it is fixed in the mobile push plate and blocks optocoupler baffle, detection is provided on the pedestal Optocoupler, the detection optocoupler and blocks optocoupler baffle and cooperates shift position to detect the mobile push plate.Specifically, it is moving It when dynamic push plate promotes, blocks optocoupler baffle and also promotes therewith, when the light that detection optocoupler issues blocks optocoupler baffle gear by described When firmly, that is, determine that mobile push plate has been advanced into target position, controller controls the second motor stalls at this time, and mobile push plate stops Thrust into.
Preferably, second motor is linear motor, the mobile feeding of blood sample automatic mixing device, using horizontal feed Mode.Specifically, in the embodiment of the present invention, blood sample automatic mixing device first carries out horizontal feed straight line from its ready position Motor driven, the sliding screw nut body of linear motor drive mobile push plate, optocoupler baffle and fixed block to rack for test tube side To horizontal feed to suitable position, with all correlator members and part synchro-feed for being associated with installation on fixed block, including One bracket, second support and third bracket and its components mounted thereto;The suitable position fed is then third level Fixed test tube storehouse center and the test tube central coaxial lifted on bracket, as shown in Figure 2.Test tube clamping jaw is micro together with what is picked up Peripheral blood acquisition test tube first carries out lowering action, and falling head is that test tube bottom is touched or fixed close on the second horizontal bracket In rubber test tube support with inner sunken face;Then test tube clamping jaw executes horizontal feed and moves to water away from rack for test tube direction Flat ready bit, so that test tube clamping jaw is kept completely separate with by folder test tube.So far, it completes to execute blood sample mixed well operation preparation, with It is operated with carrying out specific mix as described above, referring specifically to preceding sections, and will not be described here in detail.
With reference to specific embodiment, although the present invention is illustrated in the specification and illustrated in the drawings, it is to be understood that, In the case where not departing from the scope of the invention defined in claim, technical field personnel can make it is a variety of change with And a variety of alternative many of elements of equivalent.Moreover, technical characteristic, element between mode embodied herein and/ Or the combination and collocation of function are clearly apparent, therefore according to these disclosure of that, technical field personnel can Another embodiment can be optionally incorporated by understanding the technical characteristic in embodiment, element and/or function In, unless above content has other description.In addition, introduction according to the present invention is fitted in the range for not departing from essence of the invention Answer special situation or material can be with many modifications may be made.Therefore, the present invention is not limited to graphic of attached drawing institute is other specific Embodiment and the specific reality described in this description as at present to implement preferred forms contemplated by the present invention Mode is applied, and the present invention is intended to include all embodiments fallen into description above and scope of the appended claims.

Claims (14)

1. a kind of blood sample automatic mixing device, which is characterized in that the blood sample automatic mixing device includes first support, second Frame and flexible column, the second support are fastened on above the first support by the flexible column, and can be relative to The first support carries out rotary swing and vibration, and the flexible column is between the first support and the second support Part in hourglass shape be arranged.
2. a kind of blood sample automatic mixing device according to claim 1, which is characterized in that the blood sample automatic mixing device It further include the first driving unit and eccentric block, first driving unit is arranged in the second support, first driving The eccentric block is fixed on unit output shaft end, the eccentric block is single around the first driving under first driving unit driving First axis executes rotation, drives the second support to carry out rotary swing and vibration relative to the first support, in turn Support is driven to be fixed on the rotary swing of the synchronous progress of test tube and vibration of the second support.
3. a kind of blood sample automatic mixing device according to claim 1, which is characterized in that the blood sample automatic mixing device It further include third bracket and test tube storehouse, the first support is connected with third bracket by support rod, and the test tube storehouse setting exists On the third bracket.
4. a kind of blood sample automatic mixing device according to claim 1, which is characterized in that be provided in the second support Test tube pallet, the test tube pallet are equipped with inner sunken face, and the inner sunken face is used to support the bottom of test tube to accommodate test tube In the test tube storehouse.
5. a kind of blood sample automatic mixing device according to claim 3, which is characterized in that is arranged in the second support One groove and the second groove, a part of the support rod are arranged in first groove, and the one of the flexible column Part is located in second groove.
6. a kind of blood sample automatic mixing device according to claim 3, which is characterized in that the side portion of the second support On open up third groove, the third groove be a side opening arc-shaped structure;The quantity of the support rod is two, In a part of a support rod be set in first groove, a part of another support rod is set to the third In groove.
7. a kind of blood sample automatic mixing device according to claim 6, which is characterized in that the test tube storehouse includes hollow shaft Set, the hollow shaft are set on the third cradle top, and the position that the third bracket corresponds to the hollow shaft sleeve offers Through-hole, the hollow shaft sleeve and the through-hole are for accommodating test tube to constrain test tube moving position.
8. a kind of blood sample automatic mixing device according to claim 1, which is characterized in that the flexible column is by rubber or silicon Glue material is made, or is spring.
9. a kind of blood sample automatic mixing device according to claim 5, which is characterized in that the side of the second support is set It is equipped with concave station, second groove is set on the concave station, the flexible column includes top column cap and cylinder, the upper post Head is set on the concave station surface, and the cylinder is set in second groove, and the cross section of the top column cap is Circular configuration, the cylinder are cylindrical structure, and the diameter of the circular configuration cross section of the top column cap is greater than the cylinder The diameter of cylindrical structure.
10. a kind of blood sample automatic mixing device according to claim 1, which is characterized in that the flexible column includes lower part Column cap, the lower part column cap lower section are provided with connector, are provided with connecting hole in the first support, which is arranged in institute It states in connecting hole so that flexible column to be fixed in the first support.
11. a kind of blood cell analysis equipment comprising a kind of described in any item blood sample automatic mixing devices of claim 1-10, It is characterized in that, the blood cell analysis equipment further includes auto-feeder, the auto-feeder includes pedestal and biography Component is moved, is fixed with the second driving unit on the pedestal, the transmission component is movably disposed on pedestal, the transmission Component connects the first support, and second driving unit drives the transmission component mobile relative to the pedestal, described Transmission component drives the first support mobile so that the test tube storehouse to be moved to the ready position for receiving blood specimen collection test tube.
12. a kind of blood cell analysis equipment according to claim 11, which is characterized in that the transmission component includes sliding Block, slide rail, fixed block, mobile push plate and sliding screw nut body, the slide rail are fixed on the pedestal, institute Sliding block is stated to be set in the slide rail;The sliding screw nut body is pushed away with second driving unit and movement respectively Plate connection;The fixed block is connect with the first support and the sliding block respectively, and the mobile push plate is in sliding screw nut Push the fixed block and sliding block mobile under the action of mechanism, the sliding block is moved along the slide rail to guide fixed block to move Dynamic direction.
13. a kind of blood cell analysis equipment according to claim 12, which is characterized in that be fixed in the mobile push plate Optocoupler baffle is blocked, detection optocoupler is provided on the pedestal, the detection optocoupler cooperates with optocoupler baffle is blocked to detect The shift position of the mobile push plate.
14. a kind of blood cell analysis equipment according to claim 11, which is characterized in that the blood cell analysis equipment is also Including test tube clamping jaw, the test tube clamping jaw is used to first carry out lowering action together with the micro peripheral blood acquisition test tube picked up, under In the touching of test tube bottom or the fixed rubber test tube support with inner sunken face close on the second horizontal bracket, then drop height is Test tube clamping jaw executes horizontal feed and away from rack for test tube direction moves to horizontal ready bit so that test tube clamping jaw with by folder test tube It is kept completely separate.
CN201910324795.4A 2018-04-24 2019-04-22 A kind of blood sample automatic mixing device and blood cell analysis equipment Pending CN110398594A (en)

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CN201920555267.5U Active CN210982481U (en) 2018-04-24 2019-04-22 Automatic mixing device of blood sample and blood cell analytical equipment
CN201910324795.4A Pending CN110398594A (en) 2018-04-24 2019-04-22 A kind of blood sample automatic mixing device and blood cell analysis equipment
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CN201910325590.8A Active CN110398598B (en) 2018-04-24 2019-04-22 Automatic mixing device of blood sample and blood cell analysis equipment
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CN210982482U (en) 2020-07-10
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