CN110354203A

CN110354203A - A kind of Chinese medicine composition, purposes and preparation method thereof

Info

Publication number: CN110354203A
Application number: CN201810312403.8A
Authority: CN
Inventors: 张贵民; 李蔚群
Original assignee: Lunan Pharmaceutical Group Corp
Current assignee: Lunan Pharmaceutical Group Corp
Priority date: 2018-04-09
Filing date: 2018-04-09
Publication date: 2019-10-22

Abstract

The invention discloses a kind of Chinese medicine compositions with health care function, are made of following traditional Chinese medicinal components: ginseng 5-35 parts by weight, ganoderma lucidum 15-50 parts by weight, rhizoma polygonati 15-105 parts by weight, fructus lycii 15-60 parts by weight, Cortex Eucommiae 5-35 parts by weight, dried orange peel 5-35 parts by weight.The present invention discloses using above-mentioned Chinese medicine composition as raw material, there is the health food or drug of function of physical fatigue alleviation made of premenstrual processing, extraction, preparation and packaging and other steps.Stable and controllable for quality using health food made from inventive formulation and preparation method thereof or drug, healthcare function is definite, is suitble to sub-health population long-term consumption.

Description

A kind of Chinese medicine composition, purposes and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine compositions, purposes and preparation method thereof, belong to medicines and health protection field.

Background technique

With the development of society and the progress in epoch, the rhythm of people's life and work is constantly accelerated, from social and each The pressure of aspect is continuously increased, in addition environmental pollution and itself various undesirable living habit, and sub-health state crowd is in year by year Increase trend.Sub-health state refers to that the body and mind of people is in a kind of healthy low-quality state between disease and health, though it is body Without specific disease, but on body, psychologically there is the feeling and symptom of various discomforts, such as insomnia, out of strength, physically-draining, Emotional lability (including nervous, low, irritated etc.), so that vigor and a kind of physiological status to the decline of extraneous adaptive faculty is presented, Inferior health is the important origin and basis of a variety of diseases of human body.Sub-health population is with fatigue, sleep disturbance, amnesia, oropharynx are uncomfortable, Giddy, eye fatigue, pain, emotional lability are general features, and fatigue is sub-health population performance the most outstanding.

Modern medicine thinks that fatigue is that body crosses function caused by use (transfiniting) and reduces and the state of body discomfort occur. Cross with include the time it is excessive etc. with intensity too long.Cross reduced with, function, body discomfort refers not only to physical strength, also refer to it is mental with it is psychological； Entirety is referred not only to, also refers to part.Body discomfort is mainly shown as that fatigue is sleepy, may occur in which dizziness, amnesia, sleep quality decline etc. Simultaneous phenomenon.Wherein fatigue is broadly divided into physiologic fatigability and pathological fatigue two major classes, the physiological occurred after activity it is tired Labor is a kind of normal phenomenon.Physiologic fatigability includes that physical fatigue, mental fatigue, psychology (spirit) fatigue and mixed type are tired again 4 kinds of labor etc..Wherein physical fatigue is called exercise induced fatigue, refers to that " organism physiology process cannot be tieed up as caused by motion itself Hold its function on a specified level and/or cannot maintain scheduled exercise intensity " locomitivity decline the phenomenon that.

The factors such as the generation and the consumption of energy substance, the accumulation of metabolite, the stabilization sexual maladjustment of interior environment of fatigue are closed System is close.When human body for a long time, carry out excess load physical exertion when, muscle (skeletal muscle) group persistently or exceedingly receive Contracting can generate the metabolism such as lactic acid, carbon dioxide, water, serum urea nitrogen production while largely consumption intramuscular energy substance Object, the acidity in blood also will increase.After these metabolites gather a certain amount of in muscle, so that it may interfere muscle cell Mobility, make muscle not and can be carried out the flexible of continuous and effective, and human tissue cell and brain centres nerve system can be stimulated System.Excessive metabolite enters blood and runs whole body, makes one to generate the uncomfortable feeling such as limbs fatigue, sleepy, DOMS, It makes one to feel that body is tired, fatigue just produces.

Fatigue as that cannot restore completely for a long time, and cerebral cortex function will receive destruction, and nerve-Humoral immunity function is disorderly Disorderly, each organ, system functional state be abnormal variation, if intervened not in time, then over fatigue can be transferred to by fatigue And/or confirmed fatigue, i.e., pathological state is transferred to from physiological status.Certainly it can also make body recovery by positive medical treatment and correction To health status, it is this recognize emphasized just with Traditional Chinese medical theory " preventive treatment of disease ' thought it is perfectly in harmony.

Doctor trained in Western medicine there is no effective treatment means to the fatigue of inferior health at present, and traditional Chinese medicine from the angle of " preventiveing treatment of disease " to tired The understanding of labor and intervention have one's own knack.Traditional Chinese medicine class healthy food material is rich and varied, has Small side effects, safety The characteristic and advantage that high, prevention and treatment combines, and can achieve the purpose that treating both manifestation and root cause of disease, obtain the approval and attention of more and more people. Also, alleviation physical fatigue health food suitable population's quantity is more, and the market demand is big, and mass foundation is good, has a vast market Prospect.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine composition, the Chinese medicine composition is by ginseng, ganoderma lucidum, rhizoma polygonati, fructus lycii Son, Cortex Eucommiae, 6 taste Chinese medicinal composition of dried orange peel have the healthcare function for alleviating physical fatigue.

A kind of Chinese medicine composition with health care function of the present invention, is made of following traditional Chinese medicinal components:

Ginseng 5-35 weight Ganoderma Lucidum 15-50 parts by weight rhizoma polygonati 15-105 parts by weight

Fructus lycii 15-60 parts by weight Cortex Eucommiae 5-35 parts by weight dried orange peel 5-35 parts by weight.

The Chinese medicine composition preferred weight proportion are as follows:

Ginseng 15-30 weight Ganoderma Lucidum 25-45 parts by weight rhizoma polygonati 55-85 parts by weight

Fructus lycii 25-55 parts by weight Cortex Eucommiae 15-30 parts by weight dried orange peel 15-30 parts by weight.

The Chinese medicine composition best weight ratio are as follows:

25 weight Ganoderma Lucidum of ginseng, 37.5 parts by weight rhizoma polygonati, 75 parts by weight

50 parts by weight Cortex Eucommiae of fructus lycii, 25 parts by weight dried orange peel, 25 parts by weight.

Chinese medicine thinks that fatigue belongs to the scope of Chinese medicine " consumptive disease ", evil when consumptive disease is mainly due to exogenous disease, tired excessive, the feelings will of labor Do not relax, diet is uncomfortable, insufficiency of natural endowment or prolonged illness are lost greatly after being ill in conditioning etc., lead to internal injury of being overworked for a very long period, body and the spirit is crossed consumption, gradually lost to internal organs Damage, insufficiency of generating and transforming QI and blood, caused by Qi dysfunction.Its basic pathogenesis can be summarized as it is empty with it is strongly fragrant, sick position is related to the five internal organs, mainly with spleen, It is outstanding first when pushing away spleen based on liver and kidney, i.e., Spleen-Qi Deficiency, kidney essense lose, hepatic depression, be Primary Asthenia-Secondary Sthenia Syndrome.Therefore, treatment basic principle is " damage person's benefit ", " diseases caused by over-strain should be treated by warming ", establish eliminate physical fatigue the legislation rules for the treatment of be replenish qi to invigorate the spleen, liver-kidney tonifying, mental-tranquilization. Ginseng, ganoderma lucidum, rhizoma polygonati, fructus lycii, Cortex Eucommiae, dried orange peel are selected accordingly, form the formula with function of physical fatigue alleviation.

We, ginseng sweet temperature, tonify deficiency benefit health, slight bitter is not dry, is longer than tonifying vital QI, the deficiency of vital energy of tonifying lung spleen, and help healthy tendency it It is healthy and vigorous, and energy nourishing generate fluid, nourishing blood and tranquilization is the key medicine of qi-restoratives, is monarch drug in a prescription.Ganoderma lucidum, benefiting qi and nourishing blood is relieving cough and asthma, nourishing heart peace Mind is losed heart for consumptive disease, is had no peace of mind, palpitaition of having a sleepless night, deficiency syndrome of the lung cough and asthma, and do not feel like eating etc. is to use with ginseng " mutual reinforcement between ", can augment The strong power of benefit, is altogether monarch drug in a prescription.

Marrow is filled out in rhizoma polygonati tonifying middle-Jiao and Qi, enriching yin, and the five internal organs is made to reconcile, muscle sufficiency, and it is the product of strengthening by means of tonics that marrow is strong strong；Chinese holly The sweet cold profit of matrimony vine, color is red to be entered to walk blood system, is apt to tonifying kidney and benefiting sperm, is nourished the liver to improve visual acuity；Cortex Eucommiae nourishing liver and kidney, strengthening the essence gas, strengthening the bones and muscles；Three 5 With liver-kidney tonifying, the power enhancing of supplementing qi and nourishing yin, is all ministerial drug.

Dried orange peel is arduous and warm, and pungent to open bitter drop, function is apt to regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm, stomach function regulating is amusing, with replenish qi to invigorate the spleen, tonifying liver Promoting the circulation of qi is not forgotten in the product compatibility of kidney-nourishing, tonifying Qi, and sound is suitable, makes to mend without stagnant, and it is adjutant that row is grown and oiliness without dissipating.

The above 6 taste Chinese medicine, according to Chinese medicine " monarch " and " to medicine " compatibility theory, and follow Chinese medicine " treatinging deficiency with tonification ", The tune of " being scheduled to last with flat " is mended theory and carries out prescription, so that 6 medicines is harmonious, is also mended and also dredge, and thin mend combines, and is complemented each other, is brought out the best in each other, altogether Play replenish qi to invigorate the spleen, liver-kidney tonifying, mental-tranquilization function, it is weary to cure mainly burnout caused by kidney deficiency and liver, the insufficiency of heart and spleen, mind dystrophy Power, loss of appetite, insomnia forgetfulness are had a dizzy spell, pale complexion, soreness and weakness of waist and knees etc., to have function of relieving physical fatigue.

It is a further object to provide a kind of health food containing above-mentioned Chinese medicine composition or drug and its systems Preparation Method, the health food or drug are oral liquid or oral solid formulation.

Preferably, the oral liquid is health liquor or oral solution；Preferably, the oral solid formulation is piece Agent, capsule, particle or jelly, biscuit, candy, cake.

The health food or drug preparation method the following steps are included:

A, 6 kinds of ginseng, ganoderma lucidum, rhizoma polygonati, fructus lycii, Cortex Eucommiae, dried orange peel raw medicinal materials are taken, wherein ginseng, ganoderma lucidum and rhizoma polygonati are cut Piece, Cortex Eucommiae, dried orange peel dissection block, fructus lycii cleans, spare；

B, the raw medicinal material medicine materical crude slice processed through step A is weighed by formula ratio, is uniformly mixed, is set in pot for solvent extraction, add 3-4 The white wine of 35%-45%vol is measured again, and room temperature, closed dipping 10-20 days release maceration extract, while with 100-200 mesh habotai Filtration, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 35%-45% with 2 times presses every kilogram of medicine materical crude slice 1-3ml/min speed diacolation, receives Percolate, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

Merge above-mentioned maceration extract and percolate, stir evenly, room temperature, closed preservation obtain total extract；

C, total extract described in step B is weighed, white wine, purified water, corrigent is added by formula ratio, stirs evenly, makes wine Precision reaches 30%vol-38%vol, in the closed storage -48h for 24 hours of 2 DEG C of -10 DEG C of freezers, obtains cold heavy liquid, simultaneously with plate frame filter It is filtered for the first time using diatomite as filter aid, obtains and filter wine liquid for the first time, then using plate frame filter and using pulp board as filter material Secondary filter is carried out, clarification wine liquid is obtained, filling, packaging obtains health liquor；

Or removal ethyl alcohol is concentrated under reduced pressure in total extract described in step B and obtains concentrate, as effective component, then add auxiliary material Health food or drug is made.

Preferably, step B adds the white wine of 3 times of amount 40%vol, room temperature, closed dipping 15 days.

Preferably, the white wine that the medicine materical crude slice after dipping measures 40%vol with 2 times presses every kilogram of medicine materical crude slice 2ml/min speed diacolation.

Preferably, corrigent described in step C is honey, rock sugar, white granulated sugar, acesulfame potassium, honey element, Aspartame, sweet tea One or more of leaf chrysanthemum glycosides, D-sorbite, maltitol or Sucralose, most preferably rock sugar.

The prepared slices of Chinese crude drugs according to the present invention and its processing specification are pressed existing " Chinese Pharmacopoeia " relevant regulations and are executed.

Health liquor of the present invention extracts the technique combined using normal temperature dipping with diacolation, opposite can shorten the production cycle, And using white wine as diacolation novel solvent, concentration difference caused by being flowed using white wine promotes the high-efficiency dissolution of effective component to spread, It efficiently solves and stores the technical problem containing big medicine amount liquid after impregnating in the dregs of a decoction, greatly improve in raw medicinal material medicine materical crude slice effectively The rate of transform of ingredient avoids resource excess waste, improves resource utilization and production efficiency.

Health liquor of the present invention is removed after preparing, constant volume obtains clarification wine liquid using the cold heavy technique combined with filtering Precipitating and impurity, removal precipitating, impurity are more thorough, it is ensured that health liquor shelf life character is stablized, no precipitating." cold heavy method " technique Signified temperature of ice house and " Chinese Pharmacopoeia " " cold place: means 2 DEG C -10 under version one " note on the use " 29 " storage " item in 2015 DEG C " consistent.

It is stable and controllable for quality using health food made from inventive formulation and preparation method thereof or drug, healthcare function Definitely, it is suitble to sub-health population long-term consumption.

The present invention discloses the Chinese medicine compositions to alleviate the use in physical fatigue health food or drug in preparation On the way.

For the healthcare function for verifying health food or drug of the present invention, inventor has carried out function of physical fatigue alleviation examination Test research.It should be noted that being the present invention representative formula and its preparation side selected by function assessment test of the present invention The resulting health liquor sample of method, the test and its knot that the other formulas and preparation method products obtained therefrom that the present invention is included are related to Fruit, it is not exhaustive one by one herein as space is limited,.

Test example 1 alleviates physical fatigue Effect study

1 material and method

1.1 experimental animal

ICR mouse, male, 18~22g of weight, quality certification number: No.37009200008562, it is dynamic by the happy experiment of Jinan friend Object is bred Co., Ltd and is provided, credit number: SCXK (Shandong) 2014007；Animal is in sub-cage rearing in Special test room, before test Adaptive feeding one week, natural lighting, drinking-water of freely ingesting, at 20 DEG C~22 DEG C, relative humidity was controlled 45% for room temperature control ~65%.

1.2 tested materials and give mode and dosage selection

This test sample used 1, sample 2 and sample 3 are respectively embodiment 1, embodiment 5 and the formula of embodiment 9 and technique Obtained health liquor sample.The recommended dose of human body is 60ml/60kg.bw, and the alcohol concentration of sample is more than 15%vol, and Recommended dose is larger, and in order to meet requirement of experiment, sample is carried out 16 times of concentrations (having removed corrigent), the experiment institute injecting amount It is equivalent to the dosage of raw sample.

It is examined referring to function of physical fatigue alleviation in the Ministry of Public Health " health food is examined and assessment technique specification (version in 2003) " Proved recipe method and working specification carry out.Each sampling test sets 5 groups, every group of 12 mouse, i.e. 1 solvent control group, 1 wine base Control group and 3 test groups, 3 samples set 9 test groups altogether, wherein the dosage of set basic, normal, high test group is respectively equivalent to 5 times, 10 times, 30 times of human body recommended intake.In view of the alcoholic strength of sample is more than 15%, needs are tested to meet, are taken 3.75ml tested material adds 7.5ml alcohol concentration to be 40% wine base, and is settled to 20ml with distilled water, by tested material alcohol concentration Adjust to 15%, as high dose group, in, low dose group measures the above-mentioned high dose group liquid of 6.67ml, 3.33ml respectively and adds wine The wine base that smart concentration is 15% is settled to 20ml, and solvent control group gives distilled water, and wine base control group gives alcohol concentration and is 15% wine base, each group is by measuring indices after daily 0.1ml/10g.bw continuous gavage 30 days.

1.3 Loaned swimming test

After last gives tested material 30min, mouse is set in swimming trunk went swimming, the depth of water about 30cm, 25 DEG C ± 0.5 of water temperature ℃.The sheet lead of 5% weight of rat-tail root load.Record mouse from swim cause the death time, as mouse swimming time.

The measurement of 1.4 serum ureas

After last gives tested material 30min, mouse is set in 30 DEG C of water went swimming 90min.Peace and quiet 60min pulls out eye after movement Ball blood sampling 0.5ml.2000 turns/min is centrifuged 15min after 4 DEG C of standing 3h, takes serum automatic clinical chemistry analyzer measurement urine Element.

1.5 hepatic glycogen measurement: anthrone method

After last gives tested material 30min, mouse is put to death, takes liver to be blotted after physiological saline rinses with filter paper, accurately Liver 100mg is weighed, 8mlTCA is added, 1min is homogenized, homogenate is poured into centrifuge tube, 15min is centrifuged with 3000 turns/min, it will Supernatant is transferred in another test tube.1ml supernatant is taken to be put into 10ml centrifuge tube, 95% ethyl alcohol 4ml is added in every pipe, sufficiently It mixes, erects stand overnight at room temperature.After precipitating is complete, test tube is centrifuged 15min in 3000 turns/min.It is distilled with 2ml water-soluble Glycogen is solved, with anthrone method in 620nm wavelength colorimetric estimation hepatic glycogen.

1.6 test datas statistics

-

Data are handled using SPSS13.0 statistical software.Test result is with the form table of mean and standard deviation (X ± s) Show, using variance analysis, first carry out homogeneity test of variance, variance is neat, calculates F value, F value < F_0.05, conclusion: poor between each group mean Different no significant；F value >=F_0.05, P≤0.05, with the comparative approach two-by-two of mean between multiple test groups and a control group (Dunnett method of inspection) is for statistical analysis.

2 results

Influence of 2.1 samples to the mice burden swimming time is shown in Table 1.

1 sample of table to the mice burden swimming time influence (N=12)

* P: compared with solvent control group, #P: compared with wine base control group.

Seen from table 1, there was no significant difference compared with solvent control group (P > 0.05) for wine base control group.High agent in sample 1 There are significant difference (P < in amount group, sample 2 and the low middle high dose group mice burden swimming time of sample 3 compared with solvent control group 0.05), wherein the high dose group of sample 2 and sample 3 has extremely significant sex differernce (P < 0.01) compared with solvent control group.Sample 1 The low middle high dose group mice burden swimming time has conspicuousness poor compared with wine base control group with high dose group, sample 2 in sample 3 Different (P < 0.05), wherein 2 high dose group of sample has extremely significant sex differernce (P < 0.01) compared with wine base control group.

The influence of serum urea is shown in Table 2 when 2.2 samples are to mouse movement.

When 2 sample of table is to mouse movement serum urea influence (N=12)

As can be seen from Table 2, there was no significant difference compared with solvent control group (P > 0.05) for wine base control group.1 high dose of sample High dose group and the low middle high dose group mice serum urea level of sample 2 have conspicuousness compared with solvent control group in group, sample 3 Difference (P < 0.05), wherein high dose group and 3 high dose group of sample have extremely significant property poor compared with solvent control group in sample 2 Different (P < 0.01).The low middle high dose group mice serum urea level of high dose group, sample 2 and wine base pair in sample 1 and sample 3 Comparing according to group has significant difference (P < 0.05), wherein the middle high dose group and wine of sample 1 and 3 high dose group of sample and sample 2 Base control group relatively has extremely significant sex differernce (P < 0.01).

Influence of 2.3 samples to mouse hepatic glycogen is shown in Table 3.

Influence of 3 sample of table to mouse hepatic glycogen

Seen from table 3, there was no significant difference compared with solvent control group (P > 0.05) for wine base control group.High agent in sample 1 Amount group and the low middle high dose group Mouse Liver glycogen levels of sample 2 and sample 3 have significant difference (P < compared with solvent control group 0.05), wherein high dose group has extremely significant sex differernce compared with solvent control group in 1 high dose group of sample and sample 2 and sample 3 (P < 0.01).High dose group and the low middle high dose group Mouse Liver glycogen levels of sample 2 and wine in 1 high dose group of sample, sample 3 Base control group relatively has significant difference (P < 0.05), wherein high dose group and 3 high dose group of sample and wine base pair in sample 2 Comparing according to group has extremely significant sex differernce (P < 0.01).

Above-mentioned test result shows that sample 1, sample 2 and sample 3 of the present invention can be obviously prolonged the mice burden swimming time, Serum urea when significantly reducing mouse movement, significantly improves mouse hepatic glycogen content.According to " health food is examined and assessment technique Specification (version in 2003) " criterion, this laboratory sample, which has, alleviates physical fatigue healthcare function.

Specific embodiment

The present invention is further illustrated by specific embodiment down, but relevant technical staff in the field ought to know, described in this Embodiment is not limit the invention in any way.

The preparation of 1 health liquor of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 0.5kg, ganoderma lucidum 1.5kg, rhizoma polygonati 1.5kg, Chinese holly are weighed Matrimony vine 1.5kg, Cortex Eucommiae 0.5kg, dried orange peel 0.5kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 35%vol white wine, room temperature, Closed dipping 10 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 35%vol with 2 times presses every kilogram of medicine materical crude slice 1ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

Merge above-mentioned maceration extract and percolate, stir evenly, room temperature, closed preservation obtain total extract.

C, total extract described in step B is weighed, white wine, purified water, white granulated sugar is added by formula ratio, stirs evenly, makes wine Precision reaches 30%vol, obtains semi-finished product wine liquid 100L, for 24 hours in the closed storage of 2-10 DEG C of freezers, obtains cold heavy liquid, is filtered with plate and frame Device is simultaneously filtered using diatomite as filter aid for the first time, is obtained and is filtered wine liquid for the first time, then is with plate frame filter and with pulp board Filter material carries out secondary filter, obtains clarification wine liquid, filling, and packaging obtains health liquor finished product.

The preparation of 2 health liquor of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.5kg, ganoderma lucidum 4.0kg, rhizoma polygonati 7.5kg, Chinese holly are weighed Matrimony vine 5.0kg, Cortex Eucommiae 2.5kg, dried orange peel 2.5kg are uniformly mixed, set in pot for solvent extraction, add the white wine of 3 times of 37%vol, room temperature, close It closes dipping 15 days, releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 37%vol with 2 times presses every kilogram of medicine materical crude slice 2ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, white wine, purified water, maltitol is added by formula ratio, stirs evenly, makes Alcoholic strength reaches 33%vol, obtains semi-finished product wine liquid 100L, in 2-10 DEG C of closed storage 48h of freezer, cold heavy liquid is obtained, with plate and frame mistake Filter is simultaneously filtered using diatomite as filter aid for the first time, is obtained and is filtered wine liquid for the first time, then with plate frame filter and with pulp board Secondary filter is carried out for filter material, obtains clarification wine liquid, filling, packaging obtains health liquor finished product.

The preparation of 3 health liquor of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 1.5kg, ganoderma lucidum 2.5kg, rhizoma polygonati 5.5kg, Chinese holly are weighed Matrimony vine 2.5kg, Cortex Eucommiae 1.5kg, dried orange peel 1.5kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 38%vol white wine, room temperature, Closed dipping 15 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 38%vol with 2 times presses every kilogram of medicine materical crude slice 2ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, white wine, purified water, Aspartame is added by formula ratio, stirs evenly, makes Alcoholic strength reaches 34%vol, obtains semi-finished product wine liquid 100L, for 24 hours in the closed storage of 2-10 DEG C of freezers, cold heavy liquid is obtained, with plate and frame mistake Filter is simultaneously filtered using diatomite as filter aid for the first time, is obtained and is filtered wine liquid for the first time, then with plate frame filter and with pulp board Secondary filter is carried out for filter material, obtains clarification wine liquid, filling, packaging obtains health liquor finished product.

The preparation of 4 health liquor of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.0kg, ganoderma lucidum 3.0kg, rhizoma polygonati 6.5kg, Chinese holly are weighed Matrimony vine 5.0kg, Cortex Eucommiae 2.5kg, dried orange peel 2.5kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 44%vol white wine, room temperature, Closed dipping 20 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 44%vol with 2 times presses every kilogram of medicine materical crude slice 3ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, white wine, purified water, honey, stevioside glycosides and sorbose is added by formula ratio Alcohol stirs evenly, and makes alcoholic strength up to 38%vol, obtains semi-finished product wine liquid 100L, for 24 hours in the closed storage of 2-10 DEG C of freezers, obtains cold Heavy liquid, is filtered for the first time using plate frame filter and using diatomite as filter aid, obtains and filter wine liquid for the first time, then with plate and frame mistake Filter simultaneously carries out secondary filter by filter material of pulp board, obtains clarification wine liquid, and filling, packaging obtains health liquor finished product.

The preparation of 5 health liquor of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.5kg, ganoderma lucidum 3.75kg, rhizoma polygonati 7.5kg, Chinese holly are weighed Matrimony vine 5.0kg, Cortex Eucommiae 2.5kg, dried orange peel 2.5kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 40%vol white wine, room temperature, Closed dipping 15 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 40%vol with 2 times presses every kilogram of medicine materical crude slice 2ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, white wine, purified water, rock sugar is added by formula ratio, stirs evenly, makes alcohol Degree reaches 36%vol, obtains semi-finished product wine liquid 100L, in 2-10 DEG C of closed storage 48h of freezer, cold heavy liquid is obtained, with plate frame filter And filtered for the first time using diatomite as filter aid, obtain and filter wine liquid for the first time, then with plate frame filter and with pulp board be filter Material carries out secondary filter, obtains clarification wine liquid, filling, and packaging obtains health liquor finished product.

The preparation of 6 health liquor of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.5kg, ganoderma lucidum 4.5kg, rhizoma polygonati 7.0kg, Chinese holly are weighed Matrimony vine 4.5kg, Cortex Eucommiae 3.0kg, dried orange peel 2.0kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 36%vol white wine, room temperature, Closed dipping 20 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 36%vol with 2 times presses every kilogram of medicine materical crude slice 1ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, white wine, purified water, honey element is added by formula ratio, stirs evenly, makes wine Precision reaches 32%vol, obtains semi-finished product wine liquid 100L, for 24 hours in the closed storage of 2-10 DEG C of freezers, obtains cold heavy liquid, is filtered with plate and frame Device is simultaneously filtered using diatomite as filter aid for the first time, is obtained and is filtered wine liquid for the first time, then is with plate frame filter and with pulp board Filter material carries out secondary filter, obtains clarification wine liquid, filling, and packaging obtains health liquor finished product.

The preparation of 7 health liquor of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 1.0kg, ganoderma lucidum 4.5kg, rhizoma polygonati 9.5kg, Chinese holly are weighed Matrimony vine 5.0kg, Cortex Eucommiae 3.0kg, dried orange peel 3.0kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 43%vol white wine, room temperature, Closed dipping 10 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 43%vol with 2 times presses every kilogram of medicine materical crude slice 2ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, white wine, purified water, acesulfame potassium is added by formula ratio, stirs evenly, makes wine Precision reaches 37%vol, obtains semi-finished product wine liquid 100L, for 24 hours in the closed storage of 2-10 DEG C of freezers, obtains cold heavy liquid, is filtered with plate and frame Device is simultaneously filtered using diatomite as filter aid for the first time, is obtained and is filtered wine liquid for the first time, then is with plate frame filter and with pulp board Filter material carries out secondary filter, obtains clarification wine liquid, filling, and packaging obtains health liquor finished product.

The preparation of 8 health liquor of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.0kg, ganoderma lucidum 4.5kg, rhizoma polygonati 10.0kg, Chinese holly are weighed Matrimony vine 4.5kg, Cortex Eucommiae 3.0kg, dried orange peel 2.5kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 41%vol white wine, room temperature, Closed dipping 10 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 41%vol with 2 times presses every kilogram of medicine materical crude slice 3ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, white wine, purified water, rock sugar is added by formula ratio, stirs evenly, makes alcohol Degree reaches 35%vol, obtains semi-finished product wine liquid 100L, for 24 hours in the closed storage of 2-10 DEG C of freezers, cold heavy liquid is obtained, with plate frame filter And filtered for the first time using diatomite as filter aid, obtain and filter wine liquid for the first time, then with plate frame filter and with pulp board be filter Material carries out secondary filter, obtains clarification wine liquid, filling, and packaging obtains health liquor finished product.

The preparation of 9 health liquor of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 3.5kg, ganoderma lucidum 5.0kg, rhizoma polygonati 10.5kg, Chinese holly are weighed Matrimony vine 6.0kg, Cortex Eucommiae 3.5kg, dried orange peel 3.5kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 45%vol white wine, room temperature, Closed dipping 20 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 45%vol with 2 times presses every kilogram of medicine materical crude slice 3ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, white wine, purified water, maltitol and acesulfame potassium, stirring is added by formula ratio Uniformly, make alcoholic strength up to 38%vol, obtain semi-finished product wine liquid 100L, in 2-10 DEG C of closed storage 48h of freezer, obtain cold heavy liquid, with Plate frame filter is simultaneously filtered using diatomite as filter aid for the first time, is obtained and is filtered wine liquid for the first time, then simultaneously with plate frame filter Secondary filter is carried out by filter material of pulp board, obtains clarification wine liquid, filling, packaging obtains health liquor finished product.

The preparation of 10 health liquor of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 3.0kg, ganoderma lucidum 4.5kg, rhizoma polygonati 8.5kg, Chinese holly are weighed Matrimony vine 5.0kg, Cortex Eucommiae 3.0kg, dried orange peel 3.0kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 39%vol white wine, room temperature, Closed dipping 20 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 39%vol with 2 times presses every kilogram of medicine materical crude slice 2ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, white wine, purified water, white granulated sugar and honey is added by formula ratio, stirring is equal It is even, make alcoholic strength up to 31%vol, obtain semi-finished product wine liquid 100L, for 24 hours in the closed storage of 2-10 DEG C of freezers, cold heavy liquid is obtained, with plate Frame-type filter is simultaneously filtered using diatomite as filter aid for the first time, is obtained and is filtered wine liquid for the first time, then with plate frame filter and with Pulp board is that filter material carries out secondary filter, obtains clarification wine liquid, filling, and packaging obtains health liquor finished product.

The preparation of 11 oral solution of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.5kg, ganoderma lucidum 3.0kg, rhizoma polygonati 6.0kg, Chinese holly are weighed Matrimony vine 4.5kg, Cortex Eucommiae 2.5kg, dried orange peel 3.0kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 42%vol white wine, room temperature, Closed dipping 10 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 42%vol with 2 times presses every kilogram of medicine materical crude slice 2ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, weigh total extract described in step B, removal ethyl alcohol be concentrated under reduced pressure and obtains concentrate, by formula ratio addition purified water, D-sorbite stirs evenly, and obtains semi-finished product oral solution 100L, is filtered using plate frame filter and by filter material of pulp board, It is filling, it sterilizes, packaging obtains oral solution finished product.

The preparation of 12 oral solution of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 1.5kg, ganoderma lucidum 3.0kg, rhizoma polygonati 8.5kg, Chinese holly are weighed Matrimony vine 6.0kg, Cortex Eucommiae 2.5kg, dried orange peel 2.5kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 36%vol white wine, room temperature, Closed dipping 20 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 36%vol with 2 times presses every kilogram of medicine materical crude slice 3ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, weigh total extract described in step B, removal ethyl alcohol be concentrated under reduced pressure and obtains concentrate, by formula ratio addition purified water, Aspartame and white granulated sugar, stir evenly, and obtain semi-finished product oral solution 100L, using plate frame filter and using pulp board as filter material into Row filtering, it is filling, it sterilizes, packaging obtains oral solution finished product.

The preparation of 13 oral solution of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 3.0kg, ganoderma lucidum 2.5kg, rhizoma polygonati 8.0kg, Chinese holly are weighed Matrimony vine 7.5kg, Cortex Eucommiae 2.5kg, dried orange peel 3.0kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 40%vol white wine, room temperature, Closed dipping 15 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

C, weigh total extract described in step B, removal ethyl alcohol be concentrated under reduced pressure and obtains concentrate, by formula ratio addition purified water, Rock sugar stirs evenly, and obtains semi-finished product oral solution 100L, is filtered using plate frame filter and by filter material of pulp board, filling, Sterilizing, packaging, obtains oral solution finished product.

The preparation of 14 tablet of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 1.0kg, ganoderma lucidum 4.0kg, rhizoma polygonati 8.5kg, Chinese holly are weighed Matrimony vine 2.0kg, Cortex Eucommiae 2.5kg, dried orange peel 1.5kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 40%vol white wine, room temperature, Closed dipping 15 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 40%vol with 2 times presses every kilogram of medicine materical crude slice 1ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, removal ethyl alcohol is concentrated under reduced pressure and obtains concentrate, is spray-dried, by said extracted Resulting xeraphium, hydroxypropylcellulose, microcrystalline cellulose crush, and set in mixer and are uniformly mixed, granulation, whole grain, are added stearic Sour magnesium, tabletting after mixing to obtain the final product.

The preparation of 15 tablet of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 1.5kg, ganoderma lucidum 2.0kg, rhizoma polygonati 9.0kg, Chinese holly are weighed Matrimony vine 5.5kg, Cortex Eucommiae 2.5kg, dried orange peel 2.5kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 36%vol white wine, room temperature, Closed dipping 10 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 36%vol with 2 times presses every kilogram of medicine materical crude slice 2ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

The preparation of 16 jelly of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.0kg, ganoderma lucidum 4.0kg, rhizoma polygonati 7.5kg, Chinese holly are weighed Matrimony vine 5.5kg, Cortex Eucommiae 2.5kg, dried orange peel 3.0kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 35%vol white wine, room temperature, Closed dipping 20 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 35%vol with 2 times presses every kilogram of medicine materical crude slice 3ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, weigh total extract described in step B, removal ethyl alcohol be concentrated under reduced pressure and obtains concentrate, by formula ratio addition xylitol, Jelly powder, water are sufficiently mixed uniformly, and sterilize encapsulating jelly after boiling.

The preparation of 17 jelly of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 3.0kg, ganoderma lucidum 4.5kg, rhizoma polygonati 8.0kg, Chinese holly are weighed Matrimony vine 1.5kg, Cortex Eucommiae 0.5kg, dried orange peel 3.5kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 42%vol white wine, room temperature, Closed dipping 15 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 42%vol with 2 times presses every kilogram of medicine materical crude slice 3ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

The preparation of 18 capsule of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 1.5kg, ganoderma lucidum 2.5kg, rhizoma polygonati 6.0kg, Chinese holly are weighed Matrimony vine 3.0kg, Cortex Eucommiae 1.5kg, dried orange peel 2.5kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 40%vol white wine, room temperature, Closed dipping 20 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

C, total extract described in step B is weighed, removal ethyl alcohol is concentrated under reduced pressure and obtains concentrate, it is spray-dried to obtain medicinal extract Powder takes the resulting extract powder of said extracted that superfine silica gel powder is added by formula ratio, filling, polishes in sanding machine, rejects damaged capsule, To obtain the final product.

The preparation of 19 capsule of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.0kg, ganoderma lucidum 4.0kg, rhizoma polygonati 2.5kg, Chinese holly are weighed Matrimony vine 4.0kg, Cortex Eucommiae 2.5kg, dried orange peel 1.5kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 41%vol white wine, room temperature, Closed dipping 10 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 41%vol with 2 times presses every kilogram of medicine materical crude slice 1ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

The preparation of 20 particle of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 3.0kg, ganoderma lucidum 4.5kg, rhizoma polygonati 7.5kg, Chinese holly are weighed Matrimony vine 4.0kg, Cortex Eucommiae 2.0kg, dried orange peel 2.0kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 37%vol white wine, room temperature, Closed dipping 10 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

C, total extract described in step B is weighed, removal ethyl alcohol is concentrated under reduced pressure and obtains concentrate, it is spray-dried to obtain medicinal extract Powder takes the resulting extract powder of said extracted that dextrin is added by formula ratio, and crushing sieves with 100 mesh sieve, and sets in mixer and is uniformly mixed, sets It pelletizes in fluidised bed granulator, subpackage fills to obtain the final product.

The preparation of 21 particle of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 1.0kg, ganoderma lucidum 4.0kg, rhizoma polygonati 3.5kg, Chinese holly are weighed Matrimony vine 2.0kg, Cortex Eucommiae 3.0kg, dried orange peel 3.0kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 43%vol white wine, room temperature, Closed dipping 15 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 43%vol with 2 times presses every kilogram of medicine materical crude slice 3ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

The preparation of 22 biscuit of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.5kg, ganoderma lucidum 4.5kg, rhizoma polygonati 7.5kg, Chinese holly are weighed Matrimony vine 5.0kg, Cortex Eucommiae 2.0kg, dried orange peel 2.0kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 38%vol white wine, room temperature, Closed dipping 20 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

C, total extract described in step B is weighed, removal ethyl alcohol is concentrated under reduced pressure and obtains concentrate, concentrate is put into blender It is interior, flour is added, is uniformly mixed, dough is put into molding machine, biscuit raw embryo is made, toast 10- under 250 DEG C of furnace temperature 15min.

The preparation of 23 biscuit of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.5kg, ganoderma lucidum 3.75kg, rhizoma polygonati 7.5kg, Chinese holly are weighed Matrimony vine 5.0kg, Cortex Eucommiae 2.5kg, dried orange peel 2.5kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 45%vol white wine, room temperature, Closed dipping 15 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

The white wine that medicine materical crude slice after dipping measures 45%vol with 2 times presses every kilogram of medicine materical crude slice 1ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is taken, removal ethyl alcohol is concentrated under reduced pressure and obtains concentrate, concentrate is put into blender, Flour is added, is uniformly mixed, dough is put into molding machine, biscuit raw embryo is made, toast 10- under 250 DEG C of furnace temperature 15min.

The preparation of 24 candy of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 1.5kg, ganoderma lucidum 2.5kg, rhizoma polygonati 6.0kg, Chinese holly are weighed Matrimony vine 4.0kg, Cortex Eucommiae 2.5kg, dried orange peel 2.0kg, be uniformly mixed, set in pot for solvent extraction, add 4 times amount 36%vol white wine, room temperature, Closed dipping 10 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

C, total extract described in step B is taken, removal ethyl alcohol is concentrated under reduced pressure and obtains concentrate, white sugar and water is added, is uniformly mixed, Concentration, is prepared into candy.

The preparation of 25 candy of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 2.5kg, ganoderma lucidum 3.0kg, rhizoma polygonati 6.0kg, Chinese holly are weighed Matrimony vine 4.0kg, Cortex Eucommiae 2.5kg, dried orange peel 2.5kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 43%vol white wine, room temperature, Closed dipping 15 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

C, total extract described in step B is taken, removal ethyl alcohol is concentrated under reduced pressure and obtains concentrate, takes total extract described in step B, subtracts Pressure concentration removal ethyl alcohol obtains concentrate, and white sugar and water is added, is uniformly mixed, concentration is prepared into candy.

The preparation of 26 cake of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 1.5kg, ganoderma lucidum 2.5kg, rhizoma polygonati 5.5kg, Chinese holly are weighed Matrimony vine 6.0kg, Cortex Eucommiae 1.0kg, dried orange peel 2.5kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 44%vol white wine, room temperature, Closed dipping 10 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

C, total extract described in step B is taken, removal ethyl alcohol is concentrated under reduced pressure and obtains concentrate, puts into mixer, pours into flour Continue to stir evenly, ferment, pressing mold molding bakes to get finished product.

The preparation of 27 cake of embodiment

B, the raw medicinal material medicine materical crude slice processed through step A, ginseng 1.0kg, ganoderma lucidum 1.5kg, rhizoma polygonati 10.0kg, Chinese holly are weighed Matrimony vine 6.0kg, Cortex Eucommiae 2.0kg, dried orange peel 2.0kg, be uniformly mixed, set in pot for solvent extraction, add 3 times amount 40%vol white wine, room temperature, Closed dipping 15 days releases maceration extract, while with the filtration of 100-200 mesh habotai, room temperature, closed preservation are spare；

Claims

1. a kind of Chinese medicine composition, which is characterized in that be made of following traditional Chinese medicinal components:

2. Chinese medicine composition according to claim 1, which is characterized in that be made of following traditional Chinese medicinal components:

3. Chinese medicine composition according to claim 2, which is characterized in that be made of following traditional Chinese medicinal components:

4. a kind of health food or drug, which is characterized in that the health food or drug contain such as any one of claim 1-3 The Chinese medicine composition.

5. health food or drug according to claim 4, which is characterized in that the health food or drug are liquid oral Preparation or oral solid formulation, preferably oral liquid are health liquor or oral solution, preferably oral solid formulation For tablet, capsule, particle or jelly, biscuit, candy, cake.

6. health food according to claim 5 or drug, which is characterized in that preparation method the following steps are included:

A, 6 kinds of ginseng, ganoderma lucidum, rhizoma polygonati, fructus lycii, Cortex Eucommiae, dried orange peel raw medicinal materials are taken, wherein ginseng, ganoderma lucidum and rhizoma polygonati slice, Cortex Eucommiae, dried orange peel dissection block, fructus lycii cleans, spare；

B, the raw medicinal material medicine materical crude slice processed through step A is weighed by formula ratio, is uniformly mixed, is set in pot for solvent extraction, add 3-4 times to measure The white wine of 35%-45%vol, room temperature, closed dipping 10-20 days are released maceration extract, while being filtered with 100-200 mesh habotai, Room temperature, closed preservation, it is spare；

The white wine that medicine materical crude slice after dipping measures 35%-45% with 2 times presses every kilogram of medicine materical crude slice 1-3ml/min speed diacolation, receives diacolation Liquid, while with the filtration of 100-200 mesh habotai, it is measured to percolate up to 2 times, stops diacolation, room temperature, closed preservation；

C, total extract described in step B is weighed, white wine, purified water, corrigent is added by formula ratio, stirs evenly, makes alcoholic strength Up to 30%vol-38%vol, in the closed storage of 2 DEG C of -10 DEG C of freezers -48h for 24 hours, cold heavy liquid is obtained, with plate frame filter and with silicon Diatomaceous earth is that filter aid is filtered for the first time, obtains and filters wine liquid for the first time, then is carried out using plate frame filter and by filter material of pulp board Secondary filter obtains clarification wine liquid, filling, and packaging obtains health liquor；

Or removal ethyl alcohol is concentrated under reduced pressure in total extract described in step B and obtains concentrate, as effective component, then add food auxiliary material Health food or drug is made.

7. health food according to claim 6 or drug, which is characterized in that 3 times of amounts 40% are added in dipping in step B The white wine of vol.

8. health food according to claim 6 or drug, which is characterized in that the medicine materical crude slice after impregnating in step B is measured with 2 times 40% white wine presses every kilogram of medicine materical crude slice 2ml/min speed diacolation.

9. health food or drug according to any one of claim 4-8, which is characterized in that described in preparation step C Corrigent be honey, rock sugar, white granulated sugar, acesulfame potassium, honey element, Aspartame, stevioside glycosides, D-sorbite, maltitol or One or more of Sucralose, it is preferred that the corrigent is rock sugar.

10. a kind of Chinese medicine composition as claimed in any one of claims 1-3 preparation alleviate physical fatigue health food or Purposes in drug.