CN110346574A - Method, blood analyzing apparatus and the device of Protein Detection device multiplexing detection albumen - Google Patents
Method, blood analyzing apparatus and the device of Protein Detection device multiplexing detection albumen Download PDFInfo
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Abstract
This application discloses method, blood analyzing apparatus and devices that a kind of Protein Detection device is multiplexed detection albumen, it include the specific albumen for currently needing to detect Protein Detection device corresponding with the specific albumen is detected in the Protein Detection instruction this method comprises: receiving Protein Detection instruction；According to Protein Detection instruct in include the specific albumen and corresponding Protein Detection device information for currently needing to detect, configure the corresponding multiple detection control parameters of the Protein Detection device；Protein Detection device is acted according to the multiple detection control parameter, carries out detection operation to the sample to be tested, to obtain the content of the specific albumen.By the above-mentioned means, the application can be multiplexed Protein Detection device to detect any specific albumen.
Description
Technical field
This application involves protein detection technology fields, and the side of detection albumen is multiplexed more particularly to a kind of Protein Detection device
Method, blood analyzing apparatus and device.
Background technique
Control with national related medical policy to antibiotic requirement, medical staff wish in diagnosis early stage energy
Judge bacterium infection or virus infection, the specific proteins such as C reactive protein (CRP) are as bacterium or virus infection
Preferred index is proposed in outpatient service and occurs novel blood analysis thereupon with haemocyte test RP bundle test and set
Standby, which may be implemented haemocyte detection and C reactive protein detection.But such equipment is only provided with one
A Protein Detection device, and the detection device is only used for the detection of C reactive protein.Such setting is limited in a blood
The protein classes that can be detected on liquid analyzer cannot achieve the detection in a blood analyser multiple protein.
Summary of the invention
The application is mainly solving the technical problems that provide a kind of method of Protein Detection device multiplexing detection albumen, blood
Analytical equipment and device can be multiplexed Protein Detection device to detect any specific albumen.
In order to solve the above technical problems, the technical solution that the application uses is: it is multiple to provide a kind of Protein Detection device
With the method for detection albumen, which comprises receive Protein Detection instruction, include current need in the Protein Detection instruction
The specific albumen of detection Protein Detection device corresponding with the specific albumen is detected；According to Protein Detection instruct in include work as
The preceding specific albumen and corresponding Protein Detection device information for needing to detect, configures the corresponding multiple inspections of the Protein Detection device
Survey control parameter；Protein Detection device is acted according to the multiple detection control parameter, carries out detection operation to sample to be tested, with
Obtain the content of the specific albumen.
In order to solve the above technical problems, another technical solution that the application uses is: a kind of blood analyzing apparatus is provided,
The equipment includes Protein Detection device, processor, memory, telecommunication circuit and receiver, and the processor couples respectively
The Protein Detection device, the memory, the telecommunication circuit and the receiver, the processor, the Protein Detection
Device, the memory, the telecommunication circuit and the receiver can be realized method as described above at work.
In order to solve the above technical problems, another technical solution that the application uses is: providing a kind of with store function
Device, be stored thereon with program data, described program data realize the step in method as described above when being executed by processor.
The beneficial effect of the application is: being in contrast to the prior art, the application receives Protein Detection instruction, the egg
It include the specific albumen for currently needing to detect Protein Detection device corresponding with the specific albumen is detected in white detection instruction；Root
According to Protein Detection instruct in include the specific albumen and corresponding Protein Detection device information for currently needing to detect, described in configuration
The corresponding multiple detection control parameters of Protein Detection device；Protein Detection device is acted according to the multiple detection control parameter,
Detection operation is carried out to sample to be tested, to obtain the content of the specific albumen.Due to including currently needing in Protein Detection instruction
The specific albumen to be detected Protein Detection device corresponding with specific albumen is detected, and it is corresponding more to configure the Protein Detection device
A detection control parameter, acts Protein Detection device according to multiple detection control parameters, carries out detection operation to specific albumen
And the content of specific albumen is obtained, the corresponding multiple detection control ginsengs of specific albumen are detected by configuring Protein Detection device immediately
Number, is multiplexed Protein Detection device, that is, makes Protein Detection device be not limited to detect a certain ankyrin, but detects and appoint
The given specific albumen of meaning can make the detection method be not limited to detect special, fixed specific egg in this way
It is white, but can detecte arbitrary specific albumen makes to be embodied so as to extend the range that this method detects specific albumen
The use scope of the blood analyzing apparatus of this method is wider, more adaptable, is more in line with the demand of doctor and patient.
Detailed description of the invention
In order to more clearly explain the technical solutions in the embodiments of the present application, make required in being described below to embodiment
Attached drawing is briefly described, it should be apparent that, the drawings in the following description are only some examples of the present application, for
For those of ordinary skill in the art, without creative efforts, it can also be obtained according to these attached drawings other
Attached drawing.Wherein:
Fig. 1 is the flow diagram of one embodiment of method of the application Protein Detection device multiplexing detection albumen；
Fig. 2 is the structural schematic diagram of one embodiment of the application blood analyzing apparatus；
Fig. 3 is the structural schematic diagram for one embodiment of device that the application has store function.
Specific embodiment
Below in conjunction with the attached drawing in the embodiment of the present application, technical solutions in the embodiments of the present application carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of embodiments of the present application, rather than whole embodiments.Based on this
Embodiment in application, those of ordinary skill in the art are obtained every other under the premise of not making creative labor
Embodiment shall fall in the protection scope of this application.
Refering to fig. 1, Fig. 1 is the process signal of one embodiment of method of the application Protein Detection device multiplexing detection albumen
Figure, this method comprises:
Step S101: receiving Protein Detection instruction, include the specific albumen that currently needs to detect in Protein Detection instruction with
Detect the corresponding Protein Detection device of specific albumen.
Step S102: according to Protein Detection instruct in include the specific albumen for currently needing to detect and corresponding albumen examine
Survey device information, the corresponding multiple detection control parameters of configuration Protein Detection device.
Step S103: Protein Detection device is acted according to multiple detection control parameters, carries out detection operation to sample to be tested,
To obtain the content of specific albumen.
In the present embodiment, the quantity of Protein Detection device can be more than one, the specific knot of Protein Detection device
Structure needs the testing principle according to albumen to determine, Protein Detection device may include finishing from sample pretreatment to detection is carried out
Necessary structure member needed for process.It certainly, can also be according to reality if the quantity of Protein Detection device is two or more
Border situation (such as:, detector is all the same for testing principle, and pretreatment is all the same, pre-processes equal difference, etc.) and it is real
Border demand considers the considerations of (such as: blood analyzing apparatus cost, etc.), finishes to determine from sample pretreatment to detection is carried out
Whether necessary structure member needed for process needs certain structure members to share, and certain structure members do not share.Therefore, egg
The specific structure of white detection device is herein and without limitation.Testing principle of the more than one Protein Detection device according to albumen,
Its specific structure can be all the same, can also part it is identical, part is not identical, or is all different, it is not limited here.
Protein Detection instruction in present embodiment, which can be, to be assigned by input unit (such as touching display screen etc.),
It is also possible to assign by host (such as computer etc.), Protein Detection is instructed from He Erlai, herein and without limitation.
Multiple detection control parameters, or referred to as multiple operation control parameters, refer to multiple pre- places according to specific albumen
Manage bar part and/or multiple testing conditions, and the corresponding control parameter for needing to configure or being arranged Protein Detection device.Such as: blood
Additional amount, dilution additional amount, protein reagent additional amount, reaction incubation time, reaction incubation temperature, detector relevant parameter,
Action parameter of associated components etc..For each Protein Detection device, some detection control parameters are identical, some detections
Control parameter is not identical, therefore, it is necessary first to make Protein Detection device that these detection control parameters be set or configured, be subsequent
Detection be ready.
Protein Detection device is able to detect any specific albumen, as long as the detection of any specific albumen can be examined using albumen
The testing principle for surveying device is detected.But different albumen are when specifically detecting, preprocessing process, testing conditions etc.
(i.e. corresponding multiple operation control parameters) be not it is duplicate, need previously according to its corresponding multiple operations control ginseng
Number, is configured or configures to Protein Detection device.Instructed according to Protein Detection: the first, current needs detect specific
Albumen, second, the Protein Detection device that the specific albumen is detected.Specifically, can be pre-saved in blood analyser
Having the corresponding multiple groups detection control parameter of the multiple Protein Detection device, (one group of detection control parameter includes multiple detection controls
Parameter), it, can complete configuration Protein Detection device according to the specific albumen and specific Protein Detection device information for including in instruction
Required multiple detection control parameters when carrying out the detection for the specific albumen, controller control the Protein Detection dress
It sets according to complete multiple detection control parameter movements, detection operation is carried out to sample to be tested, to obtain specific albumen
Content.
The application embodiment receives Protein Detection instruction, includes the tool for currently needing to detect in the Protein Detection instruction
Body protein Protein Detection device corresponding with the specific albumen is detected；According to Protein Detection instruct in include currently need to examine
The specific albumen and corresponding Protein Detection device information surveyed configure the corresponding multiple detection control ginsengs of the Protein Detection device
Number；Protein Detection device is acted according to the multiple detection control parameter, carries out detection operation to sample to be tested, described in obtaining
The content of specific albumen.Due to including that the specific albumen that currently needs to detect is corresponding with the specific albumen of detection in Protein Detection instruction
Protein Detection device, and configure the corresponding multiple detection control parameters of the Protein Detection device, make Protein Detection device according to
The movement of multiple detection control parameters carries out detection operation to specific albumen and obtains the content of specific albumen, by configuring immediately
Protein Detection device detects the corresponding multiple detection control parameters of specific albumen, is multiplexed Protein Detection device, that is, to make egg
White detection device is not limited to detect a certain ankyrin, but detects any given specific albumen, in this way, can be with
Make the detection method be not limited to detect special, fixed specific albumen, but can detecte arbitrary specific albumen, thus
The range that this method detects specific albumen can be extended, makes the use scope of the blood analyzing apparatus of specific implementation this method more
Extensively, more adaptable, it is more in line with the demand of doctor and patient.
In one embodiment, the quantity of specific albumen is two or more.The quantity of Protein Detection device is two or more.
The quantity of Protein Detection device 21 be it is more than two, each Protein Detection device 21 is detectable specified any specific
Albumen.
Wherein, more than two Protein Detection devices can detect simultaneously；Each albumen inspection is determined according to Protein Detection instruction
It surveys specific albumen, each Protein Detection device that device currently needs to detect and detects the corresponding multiple of setting needed for specific albumen
Detect control parameter, so make each Protein Detection device according to respectively multiple operation control parameters act to sample to be tested into
Row detection operation, to obtain the content of specific albumen.
Such as: it is filled in system equipped with Protein Detection device a, Protein Detection device b, Protein Detection device c, Protein Detection
Set d, Protein Detection device e and Protein Detection device f；This 6 Protein Detection device difference are determined according to Protein Detection instruction
The albumen of detection is specific albumen a, specific albumen b, specific albumen c, specific albumen d, specific albumen e and specific albumen f；Inspection
Surveying the corresponding multiple detection control parameters being arranged needed for the Protein Detection device of this 6 albumen is respectively multiple detection control ginsengs
Number a, multiple detection control parameter b, multiple detection control parameter c, multiple detection control parameter d, multiple detection control parameter e with
And multiple detection control parameter f；And make Protein Detection device a, Protein Detection device b, Protein Detection device c, albumen inspection simultaneously
Device d, Protein Detection device e and Protein Detection device f are surveyed according to respectively multiple operation control parameter movements to sample to be detected
Product are detected, to obtain the content of specific albumen.
Certainly, the Protein Detection device more than any one can also detect simultaneously, for example, equipped with Protein Detection in system
Device a, Protein Detection device b, Protein Detection device c, Protein Detection device d, Protein Detection device e and Protein Detection device
f；Protein Detection instruction can specify Protein Detection device a and Protein Detection device b while detect, and also can specify Protein Detection
Device b and Protein Detection device c are detected simultaneously, also can specify Protein Detection device d, Protein Detection device e and albumen inspection
Device f is surveyed to detect simultaneously；Or Protein Detection instructs 1 specified Protein Detection device a and Protein Detection device b at first
It carves and detects simultaneously, 2 specified Protein Detection device d of Protein Detection instruction, Protein Detection device e and Protein Detection device f are the
Two moment (being later than for the first moment) while detection, etc..
In one embodiment, this method further include:
According to the corresponding different detection blood volumes of multiple protein, configuration, which divides in the corresponding multiple points of blood control parameters of blood device, to be examined
Survey the related content of blood volume.Specifically, to can be detection described a variety of for the corresponding different detection blood volumes of a variety of different albumen
Corresponding lowest detection blood volume when different albumen.
In another embodiment, this method further include:
According to the corresponding incubation time of multiple protein, the phase for dividing blood sequence when configuration divides blood device to carry out point blood is inside the Pass
Hold.
For each albumen when detection, it may be different for needing the detection blood volume being added.Divide blood control parameter
Refer to the parameter that point blood device should be configured when distribution detects blood sample, such as: each albumen needs the detection blood volume distributed, and is
The sequencing (being shared in the case where dividing blood device when multiple Protein Detections) of each albumen distribution detection blood volume, is each albumen
Distribution detection blood volume divides blood time, etc..In actual concrete application, the corresponding multiple points of blood of point blood device is needed to configure
Detected in control parameter blood volume and or divide the related content of blood time.
Further, this method further include: according to the corresponding incubation time of multiple protein, configuration divides blood device corresponding point of blood
The related content of sequence, specifically: for detecting the Protein Detection device of the longer albumen of incubation time, divide blood assembly first pair
It carries out point blood and operates.
Under normal conditions, different specific albumen, reaction incubation time be it is different, according to the incubation of specific albumen
Time is different, and different to the execution sequencing of specific albumen divides blood to operate, in order to be controlled by reaction incubation time
The time of entire detection process.Further, the reaction incubation time of specific albumen is longer, can preferentially make point blood device to the tool
Body protein execution divides blood to operate, and can make the time of entire detection process as most short as possible in this way, to the maximum extent in unit
Test samples as more as possible in time improve detection efficiency.
Below with a specific practical application come be described in detail it is corresponding to Protein Detection device detection control parameter configuration,
To the configuration for dividing blood control parameter and incubation time for dividing blood device for dividing the influence of blood sequence:
Firstly, the configuration of detection control parameter corresponding to Protein Detection device:
The corresponding multiple groups detection control parameter in different channels is stored in cellanalyzer (in every group of detection control parameter
Bread contains multiple detection control parameters), such as it is stored with the corresponding No. 1 group detection control parameter of No. 1 Protein Detection device, No. 2 eggs
Corresponding No. 2 groups of white detection device detect control parameter, the corresponding No. 3 groups detection control parameter of No. 3 Protein Detection devices etc..
User specifies No. 1 egg by the way that the interactive interface is (without being limited thereto, can also otherwise to specify with other main bodys)
White detection device is for measuring CRP albumen；No. 2 Protein Detection devices are for when measuring SAA albumen, controller to be according to described instruction
In include CRP albumen, SAA Protein Information read from cellanalyzer CRP albumen lowest detection blood volume be 8 microlitres,
Incubation time is 35 seconds, and the lowest detection blood volume of SAA albumen is 10 microlitres, incubation time is 20 seconds, then according to instruction middle finger
No. 1 Protein Detection device shown and No. 2 Protein Detection devices information finds out No. 1 from multiple groups detection control parameter
The corresponding No. 1 group detection control parameter of Protein Detection device and corresponding No. 2 groups of No. 2 Protein Detection devices detect control parameter,
Controller forms 1 in conjunction with incubation time 35 seconds of reading No. 1 group detection control parameters corresponding with No. 1 Protein Detection device
When number Protein Detection device measurement CRP albumen, required complete detection control parameter, No. 1 Protein Detection device is according to
Complete detection control parameter movement, detects the amount of the CRP albumen in sample to be tested.It similarly, can be to No. 2 Protein Detections
No. 2 detection control parameters of device are configured, and realize detection of No. 2 Protein Detection devices to SAA albumen.
Secondly, the configuration for dividing blood control parameter to blood device is divided:
Corresponding multicomponent blood control ginseng when point blood device carries out point blood to different channels is stored in cellanalyzer
Number (including multiple points of blood control parameters inside every component blood control parameter), is such as stored with point blood device and fills to No. 1 Protein Detection
Corresponding No. 1 component blood control parameter when carrying out point blood is set, divides blood device corresponding when carrying out point blood to No. 2 Protein Detection devices
No. 2 component blood control parameters divide blood device corresponding No. 3 components blood control parameter when carrying out point blood to No. 3 Protein Detection devices
Etc..
User passes through interactive interface specified No. 1 albumen inspection (without being limited thereto, can also otherwise to specify with other main bodys)
Device is surveyed for measuring CRP albumen；No. 2 Protein Detection devices are for when measuring SAA albumen, controller to be wrapped according in described instruction
The lowest detection blood volume that CRP albumen, the SAA Protein Information contained reads CRP albumen from cellanalyzer is 8 microlitres, SAA egg
White lowest detection blood volume is 10 microlitres, and controller controls 8 microlitres with other multiple points of blood in No. 1 component blood control parameter
Parameter combines, group component blood device corresponding complete No. 1 component blood control ginseng when carrying out point blood to No. 1 Protein Detection device
Number divides blood device to be acted according to the complete No. 1 component blood control parameter, divides blood to operate in No. 1 Protein Detection device.Together
Reason in conjunction with 10 microlitres of other multiple points of blood control parameters in No. 2 component blood control parameters, will organize component blood device to No. 2
Protein Detection device carries out corresponding complete No. 2 components blood control parameter when point blood, divides blood device according to described complete No. 2
The movement of component blood control parameter is completed to divide blood to No. 2 Protein Detection channels.
Finally, incubation time is for dividing the influence of blood sequence:
Controller reads CRP according to the CRP albumen, the SAA Protein Information that include in described instruction from cellanalyzer
The incubation time of albumen is 35 seconds, and the incubation time of SAA albumen is 20 seconds, because the incubation time ratio SAA albumen of CRP albumen
Incubation time is long, so, divide blood device first to carry out a point blood to No. 1 Protein Detection device, host software first calls No. 1 component blood control
Parameter processed recalls No. 2 component blood control parameters.
In a specific practical application, the quantity of Protein Detection device is six.Certainly, according to practical application, albumen inspection
The quantity for surveying device can be flexibly equipped with.
Wherein, specific albumen be c reactive protein, serum amyloid A protein, human chorionic gonadotrophin, growth hormone,
At least one of lutropin, alpha-fetoprotein and carcinomebryonic antigen.
C reactive protein (C-reactive protein, CRP) is infected in body or when tissue damage in blood plasma
Some protein (acute protein) steeply risen, activating complement play opsonic action with the phagocytosis for reinforcing phagocyte, remove
Invade body pathogenic microorganism and damage, necrosis, apoptosis histocyte；It is considered as that acute phase is anti-that CRP, which is first,
Albumen is answered, under normal circumstances content denier, its blood concentration sharply increases in acute injury and infection；CRP is clinically most
Common acute-phase response index.
Serum amyloid A protein (Serum Amyloid A protein, SAA) is a kind of Acute reaction protein, with
CRP is similar, to assess Acute-phase protein process；SAA is a sensitive parameter, it starts to rise after inflammatory reaction about 8h
Height, and be more than term of reference upper limit time earlier than CRP, however I d median of the CRP in normal person and the term of reference upper limit
Gap, about 10 times.Only have 5 times in SAA.Mild infection, for example, many virus infections, SAA is increased more than CRP
It is common.In infectious diseases, the absolute rise of SAA is higher than CRP, therefore SAA is measured, especially to " normal " with it is small acute
Phase reaction can provide better identification.
Mature women forms embryo because the ovum of fertilization is moved in uterine cavity after implantation, is fetus mistake in growing
Cheng Zhong, placenta syncytiotrophoblast generate a large amount of human chorionic gonadotrophin (Human Chorionic
Gonadotropin, HCG), it can be recycled and be excreted in urine by pregnant woman blood.When gestation 1~2.5 week, in serum and urine
HCG level can increase rapidly, the 8th week pregnancy period peaked, until beginning within the pregnancy period 4th month is down to medium level, and tieed up always
It holds to third trimester of pregnancy.
Growth hormone (Growth Hormone, GH) has human growth hormone equivalent effect.Can promote bone, internal organ and
Whole body growth promotes protein synthesis, influences fat and mineral metabolism, plays key effect in growth in humans's development.
Lutropin is also known as luteotropin (Luteotropic Hormone, LH), can be because of estrogen secretion before preovulatory not
Foot causes the bad and too early atrophy of corpus luteum development.Corpus luteum development is not full-time, then secreting function is not good enough, keeps progesterone secretion amount insufficient.Face
Bed shows the regular menstrual cycle, but cycle time, or there is a small amount of bleeding in the premenstrual a few days, and blood volume can be unchanged.Before menstruation
The visible glandular secretion of phase endometrial biopsy is bad or uneven.Interstitial edema is unobvious.Basal body temperature biphasic type, but rise slow
Slowly, luteal phase is relatively normal short, generally at 10 days or so.Due to pregnancy period deficiency, infertile or early abortion is often formed.
Alpha-fetoprotein (Alpha Fetoprotein, AFP) is a kind of glycoprotein, belongs to albumin family, mainly by fetus
Liver cell and yolk bag synthesis.Alpha-fetoprotein concentration with higher in fetal circulation, then declines after birth, until after raw
2~March, alpha-fetoprotein was substituted by albumin substantially, more difficult detection in blood, therefore content is extremely low in adult serum.Alpha-fetoprotein
With many important physiological functions, including transportation function, the two-way regulating function as growth regulator, immunosupress, T
Lymphocyte is apoptosis-induced etc..Alpha-fetoprotein and the occurrence and development of liver cancer and kinds of tumors are closely related, in kinds of tumors
It can express higher concentration, can be used as the positive detection index of kinds of tumors.At present clinically mainly as primary carcinoma of liver
Blood serum designated object, diagnosis and curative effect monitoring for primary carcinoma of liver.
Carcinomebryonic antigen (Carcinoembryonic Antigen, CEA) is extracted from colon cancer and embryonic tissue first
A kind of tumor associated antigen is a kind of acidoglycoprotein with human embryos antigenic characteristic, is present in endoderm cell's differentiation
And the cancer cell surface come, it is the structural proteins of cell membrane.It is formed in cytoplasm, is secreted into extracellularly by cell membrane,
Subsequently into ambient body fluid.Therefore, can from a variety of body fluid such as serum, cerebrospinal fluid, milk, gastric juice, Pleural effusions and urine, excrement and
It is detected in excreta.Carcinomebryonic antigen is a kind of broad-spectrum tumor marker, although cannot function as diagnosing the special of certain malignant tumour
Property index, but the antidiastole in malignant tumour, state of illness monitoring, in terms of, still have important clinical value.
In certain practical application, the specific albumen is not limited to protein classes mentioned above, can also be other egg
It is white.
In one embodiment, it controls corresponding Protein Detection device and is detected in sample to be tested by immunoturbidimetry and had
The content of body protein.
Immunoturbidimetry (Turbidimetric inhibition immuno assay) is that antigen-antibody combines dynamic to survey
Determine method.The basic principle is that: when antigen and antibody react and suitable (the general provision antibody of ratio in special dilution system
It is excessive) when, under the action of the poly- agent of rush of the soluble immune complex of formation in dilution system (polyethylene glycol etc.), from liquid phase
It is precipitated, forms particle, reaction solution is made turbidity occur.When antibody concentration is fixed, the amount of the immune complex of formation is with sample
The increase of middle amount of antigen and increase, the turbidity of reaction solution is consequently increased.By the turbidity and series of standards that measure reaction solution
Product control, can calculate the content of antigen in sample.Immunoturbidimetry includes Immunity transmission turbidity, Immune scatter turbidimetry
And immune latex turbidimetry method.
Wherein, in a concrete application, corresponding Protein Detection device is controlled by Immune scatter turbidimetry to be detected
Sample is detected, to obtain the content of specific albumen.
The basic principle of Immune scatter turbidimetry is: the light of certain wavelength is irradiated along trunnion axis, is encountered when passing through solution anti-
Original antibody complex particle, light are reflected by particle granules, are deflected, and the wavelength of the angle of light deflection and transmitting light and are resisted
Original antibody composite particles size and how many closely related.The intensity for scattering light is directly proportional to the content of compound, i.e., to be measured anti-
Former more, the compound of formation is also more, and scattering light is also stronger.The intensity of light is scattered also with various physical factors, is such as added anti-
Former or antibody time, the power of light source and wavelength, measurement angle etc. are closely related.Immune scatter turbidimetry is divided into rate again and dissipates
Penetrate turbidimetry and terminal scattered light urbidmetry.
It is not limited to detection method mentioned above, Protein Detection device can also pass through scattering turbidimetry performance rate method, scattering ratio
The detection methods such as turbid end-point method detect albumen.
Referring to Fig.2, Fig. 2 is the structural schematic diagram of one embodiment of the application blood analyzing apparatus, which includes albumen
Detection device 1, processor 2, memory 3, telecommunication circuit 4 and receiver 5, the difference of processor 2 coupled protein detection device 1,
Memory 3, telecommunication circuit 4 and receiver 5, processor 2, Protein Detection device 1, memory 3, telecommunication circuit 4 and receiver 5
It can be realized method as described above at work.The detailed description of related content refers to above method part, herein no longer
It is superfluous to chat.
It is the structural schematic diagram for one embodiment of device that the application has store function, the device 10 referring to Fig. 3, Fig. 3
It is stored thereon with program data 100, program data 100 realizes the step in method as described above when being executed by processor.It is related
The detailed description of content refers to above method part, no longer superfluous herein to chat.
The technical solution of the application substantially the part that contributes to existing technology or the technical solution in other words
Completely or partially can be embodied in the form of software products, this has the device of store function, including several program datas,
With so that a computer equipment (can be personal computer, server or the network equipment etc.) or processor
(processor) all or part of the steps of each embodiment the method for the application is executed.And it is above-mentioned with storage function
The device of energy includes: USB flash disk, mobile hard disk, read-only memory (ROM, Read-Only Memory), random access memory
(RAM, Random Access Memory), etc..
The foregoing is merely presently filed embodiments, are not intended to limit the scope of the patents of the application, all to utilize this
Equivalent structure or equivalent flow shift made by application specification and accompanying drawing content, it is relevant to be applied directly or indirectly in other
Technical field similarly includes in the scope of patent protection of the application.
Claims (10)
1. a kind of method of Protein Detection device multiplexing detection albumen, which is characterized in that the described method includes:
Reception Protein Detection instructs, and includes the specific albumen for currently needing to detect and the detection tool in the Protein Detection instruction
The corresponding Protein Detection device of body protein；
According to Protein Detection instruct in include the specific albumen and corresponding Protein Detection device information for currently needing to detect, match
Set the corresponding multiple detection control parameters of the Protein Detection device；
Protein Detection device is acted according to the multiple detection control parameter, detection operation is carried out to sample to be tested, to obtain
State the content of specific albumen.
2. the method according to claim 1, wherein the quantity of the specific albumen is two or more.
3. according to the method described in claim 2, it is characterized in that, the method also includes:
According to the corresponding different detection blood volumes of multiple protein, configuration, which divides in the corresponding multiple points of blood control parameters of blood device, detects blood
The related content of amount.
4. according to the method described in claim 2, it is characterized in that, the quantity of the Protein Detection device is two or more.
5. according to the method described in claim 4, it is characterized in that, the method also includes:
The related content for dividing blood sequence according to the corresponding incubation time of multiple protein, when configuration divides blood device to carry out point blood.
6. according to the method described in claim 5, it is characterized in that, the method also includes:
According to the corresponding incubation time of multiple protein, the related content for dividing blood sequence when configuration divides blood device to carry out point blood, tool
Body are as follows: for detecting the Protein Detection device of the longer albumen of incubation time, divide blood assembly first to carry out point blood to it and operate.
7. according to the method described in claim 2, it is characterized in that, the specific albumen is c reactive protein, serum amyloid sample egg
At least one of white A, human chorionic gonadotrophin, growth hormone, lutropin, alpha-fetoprotein and carcinomebryonic antigen.
8. the method according to claim 1, wherein the method also includes:
It controls the corresponding Protein Detection device to detect sample to be tested by Immune scatter turbidimetry, to obtain
State the content of specific albumen.
9. a kind of blood analyzing apparatus, which is characterized in that the equipment includes Protein Detection device, processor, memory, communication
Circuit and receiver, the processor couple the Protein Detection device, the memory, the telecommunication circuit and institute respectively
Receiver is stated, the processor, the Protein Detection device, the memory, the telecommunication circuit and the receiver exist
It can be realized the method according to claim 1 when work.
10. a kind of device with store function, is stored thereon with program data, which is characterized in that described program data are located
It manages when device executes and realizes such as the step in any one of claim 1-8 the method.
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| CN201810307568.6A CN110346574A (en) | 2018-04-08 | 2018-04-08 | Method, blood analyzing apparatus and the device of Protein Detection device multiplexing detection albumen |
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