CN110339135A - A kind of peaceful dormancy essence cream and preparation method thereof - Google Patents
A kind of peaceful dormancy essence cream and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to a kind of peaceful dormancy essence creams and preparation method thereof.The essence cream component includes: flat walnut seed extract 6~10%, Butyrospermum parkii fruit fatty oil 0.8~1.2%, cetostearyl alcohol ethylhexoate 0.8~1.2%, dipotassium glycyrrhizinate 0.2~0.3%, long pubescence Chinese yam root extract 1~1.5%, dendrobium candidum extract 0.9~1.5%, Chinese walnut extract 0.9~1.5%, Herba Cancriniae lasiocarpae flower extract 1~1.5%, grape seed extract 1~1.5%, camellia flower extract 2~3%.The essence cream can have peaceful dormancy effect well, while having preferable anti-ageing compact skin whitening effect with antitoxic heart-soothing and sedative.
Description
Technical field
The invention belongs to essence cream and its preparation field, in particular to a kind of peaceful dormancy essence cream and preparation method thereof.
Background technique
The all one's life of people is in sleep state there are about the time of one third, sleep be our human bodies itself repair it is best when
Phase is an important factor for improving the immunity of the human body, prevent and resist the disease.But with the quickening of people's rhythm of life, work and life
The pressure such as living increase, cause it is nervous, more and more people by insomnia torment, notably with anxiety, depression etc..Insomnia
It is a kind of lasting sleep matter or makes us the physiological barrier that cannot be satisfied with amount, is mainly shown as difficulty falling asleep, Yi Xing in sleep,
And have difficulty in going to sleep, early morning wakes up too early, or even lies awake all night, and is often accompanied by headache and dizzy, spiritlessness and weakness, agitation, loses one's temper, infuses
Meaning power is not concentrated, and ability to work and efficiency decline, palpitation and amnesia is confused and worried, for a long time failure of memory, body immunity
Decline.
Mainly by taking hypnotic, taking hypnotic for a long time has following harm for western medical treatment insomnia at present: first is that being easy
It forms a habit, second is that being easy to produce drug resistance, and there is risk, third is that there is certain toxicity.In recent years, there are skin care item
For treating insomnia.Chinese patent CN109758520A discloses a kind of compound essential oil with anti-insomnia effect, including 1-5 parts
Rosa Damascana, flores aurantii essential oil, absolute of jasmine, Flos Osmanthi Fragrantis quintessence oil, remote osmanthus essential oil, bergamot essential oil, lemon, peppermint essence
Oil, Chinese ilex essential oil, rose pelargonium essential oil, Rosemary Oil, deodar essential oil, sandalwood essential oil, linalool, acetic acid lavender ester and
Benzyl carbinol, 0.1-1.5 parts of angelica essential oil, styrax, olibanum, Myrrha extract and Notogineng Extract, 0.1-1.0 parts of Rhizoma Chuanxiong
Essential oil, safflower essential oil, rhizoma nardostachyos essential oil and Rhizoma Paridis extract, 5-25 parts of glycerol, 10-50 portions of edible alcohols, 10-25 parts of pure water
Mixed preparing forms；The compound essential oil has good tranquilizing the mind sedation, can be relieved intense strain, adjusts mood.It is above-mentioned special
Although benefit solves wakefulness state, fine effect is not played to skin.Present existing skin care item cannot be good
Have both anti-insomnia and skin care (such as whitening and anti-aging etc.).
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of peaceful dormancy essence creams and preparation method thereof, to overcome existing skill
Skin care item cannot have both the defect of skin care and anti-insomnia effect in art.
The present invention provides a kind of peaceful dormancy essence cream, the essence cream component according to weight percent include: glycerol 4~
6%, allantoin 0.1~0.2%, glycine betaine 2~3%, carbomer 0.4~0.5%, butanediol 2~4%, glucose amino Portugal gathers
Sugar 0.8~1.5%, collagen 1~2%, caffeine 0.1~0.8%, Sodium Hyaluronate 0.1~0.15%, ceteth -20
1~3%, flat walnut seed extract 6~10%, Butyrospermum parkii fruit fatty oil 0.8~1.2%, cetostearyl alcohol ethylhexoate 0.8
~1.2%, dipotassium glycyrrhizinate 0.2~0.3%, long pubescence Chinese yam root extract 1~1.5%, dendrobium candidum extract 0.9~
1.5%, Chinese walnut extract 0.9~1.5%, Herba Cancriniae lasiocarpae flower extract 1~1.5%, grape seed extract 1~1.5%, camellia
Flower extract 2~3%, 1~2%, 1,2- hexylene glycol 1~2% of arginine, pasque flower extract 0.3~0.4%, long and thin hot pepper
Berry extract 0.3~0.4%, palpus extractive of usnea 0.3~0.4%, the water of surplus.
The essence cream component includes: glycerol 4%, allantoin 0.1%, glycine betaine 2%, carbomer according to weight percent
0.4%, butanediol 2%, glucose aminoglucan 0.8%, collagen 1%, caffeine 0.1%, Sodium Hyaluronate 0.1%, spermaceti
Alcohol polyethers -20 1%, flat walnut seed extract 6%, Butyrospermum parkii fruit fatty oil 0.8%, cetostearyl alcohol ethylhexoate
0.8%, dipotassium glycyrrhizinate 0.2%, long pubescence Chinese yam root extract 1%, dendrobium candidum extract 0.9%, Chinese walnut extract
0.9%, Herba Cancriniae lasiocarpae flower extract 1%, grape seed extract 1%, camellia flower extract 2%, arginine 1%, 1,2- hexylene glycol
1%, pasque flower extract 0.3%, long and thin hot pepper berry extract 0.3%, palpus extractive of usnea 0.3%, the water of surplus.
The essence cream component includes: glycerol 5%, allantoin 0.15%, glycine betaine 2%, card wave according to weight percent
Nurse 0.45%, butanediol 3%, glucose aminoglucan 1%, collagen 1%, caffeine 0.5%, Sodium Hyaluronate 0.1%, spermaceti
Alcohol polyethers -20 2%, flat walnut seed extract 8%, Butyrospermum parkii fruit fatty oil 1%, cetostearyl alcohol ethylhexoate 1% are sweet
Oxalic acid dipotassium 0.25%, long pubescence Chinese yam root extract 1.2%, dendrobium candidum extract 1%, Chinese walnut extract 1%, golden button
Button flower extract 1.25%, grape seed extract 1.2%, camellia flower extract 2.5%, arginine 1%, 1,2- hexylene glycol 1%,
Pasque flower extract 0.35%, long and thin hot pepper berry extract 0.35%, palpus extractive of usnea 0.35%, the water of surplus.
The essence cream component includes: glycerol 6%, allantoin 0.2%, glycine betaine 3%, carbomer according to weight percent
0.5%, butanediol 4%, glucose aminoglucan 1.5%, collagen 2%, caffeine 0.8%, Sodium Hyaluronate 0.15%, spermaceti
Alcohol polyethers -20 3%, flat walnut seed extract 10%, Butyrospermum parkii fruit fatty oil 1.2%, cetostearyl alcohol ethylhexoate
1.2%, dipotassium glycyrrhizinate 0.3%, long pubescence Chinese yam root extract 1.5%, dendrobium candidum extract 1.5%, Chinese walnut extraction
Object 1.5%, Herba Cancriniae lasiocarpae flower extract 1.5%, grape seed extract 1.5%, camellia flower extract 3%, arginase 12 %, 1,2-
Hexylene glycol 2%, pasque flower extract 0.4%, long and thin hot pepper berry extract 0.4%, palpus extractive of usnea 0.4%, the water of surplus.
The present invention also provides a kind of preparation methods of peaceful dormancy essence cream, comprising:
(1) by glycerol 4~6%, allantoin 0.1~0.2%, glycine betaine 2~3%, carbomer 0.4~0.5% and 30.45
The mixing of~61% water, is preheating to 85 ° -90 °；
(2) by glucose aminoglucan 0.8~1.5%, collagen 1~2%, caffeine 0.1~0.8% and Sodium Hyaluronate
0.1~0.15% is scattered in butanediol 2~4%, and the dilution of 10~20% water is added；
(3) by ceteth -20 1~3%, flat walnut seed extract 6~10%, Butyrospermum parkii fruit fatty oil 0.8~
1.2% and cetostearyl alcohol ethylhexoate 0.8~1.2% mix, be preheating to 85 ° -90 °；
(4) mixed solution in step (1) after preheating is pumped into main cooker, then by the mixed solution after preheating in step (3)
It is pumped into main cooker, emulsifying, stirring, 85 ° of -90 ° of heat preservations, cooling；
(5) 40~45 ° are cooled in step (4), sequentially add solution, dipotassium glycyrrhizinate 0.2 in step (2) after dilution
~0.3%, long pubescence Chinese yam root extract 1~1.5%, dendrobium candidum extract 0.9~1.5%, Chinese walnut extract 0.9~
1.5%, Herba Cancriniae lasiocarpae flower extract 1~1.5%, grape seed extract 1~1.5%, camellia flower extract 2~3%, arginine 1
~2%, 1,2- hexylene glycol 1~2%, pasque flower extract 0.3~0.4%, long and thin hot pepper berry extract 0.3~0.4%, palpus pine
Trailing plants extract 0.3~0.4% discharges after stirring；
Material content is weight percentage in step (1)-(5).
Homogenizing time is 6~10min in the step (4)；Soaking time is 25~35min.
Mixing time is 20~30min in the step (5).
Beneficial effect
The present invention utilizes flat walnut (PRINSEPIA UTILIS) seed extract, Chinese walnut (JUGLANS
CATHAYENSIS) the combination of extract, camellia (CAMELLIA JAPONICA) flower extract can be alleviated tight with antitoxic heart-soothing and sedative
Mood is opened, can make one to go to sleep peacefully, there is peaceful dormancy effect well, in combination with long pubescence Chinese yam (DIOSCOREA
VILLOSA) root extract, dendrobium candidum (DENDROBIUM CANDIDUM) extract, Herba Cancriniae lasiocarpae (SPILANTHES
ACMELLA) flower extract, grape (VITIS VINIFERA) seed extract, have the function of anti-ageing compact skin whitening.
Specific embodiment
Present invention will be further explained below with reference to specific examples.It should be understood that these embodiments are merely to illustrate the present invention
Rather than it limits the scope of the invention.In addition, it should also be understood that, after reading the content taught by the present invention, those skilled in the art
Member can make various changes or modifications the present invention, and such equivalent forms equally fall within the application the appended claims and limited
Range.
Embodiment 1
A kind of peaceful dormancy essence cream is present embodiments provided, the essence cream component is according to weight percent are as follows: glycerol 4%, urine
Bursin 0.1%, glycine betaine 2%, carbomer 0.4%, butanediol 2%, glucose aminoglucan 0.8%, collagen 1%, caffeine
0.1%, Sodium Hyaluronate 0.1%, ceteth -20 1%, flat walnut seed extract 6%, Butyrospermum parkii fruit fatty oil
0.8%, cetostearyl alcohol ethylhexoate 0.8%, dipotassium glycyrrhizinate 0.2%, long pubescence Chinese yam root extract 1%, iron sheet stone
Dry measure used in former times extract 0.9%, Chinese walnut extract 0.9%, Herba Cancriniae lasiocarpae flower extract 1%, grape seed extract 1%, camellia extract
Object 2%, arginine 1%, 1,2- hexylene glycol 1%, pasque flower extract 0.3%, long and thin hot pepper berry extract 0.3% must sunglo
Extract 0.3%, the water of surplus.
The present embodiment additionally provides a kind of preparation method of peaceful dormancy essence cream, specifically:
(1) glycerol 4%, allantoin 0.1%, glycine betaine 2%, the water of carbomer 0.4% and 61% are mixed, is preheating to 85 °；
(2) fourth is dispersed by glucose aminoglucan 0.8%, collagen 1%, caffeine 0.1% and Sodium Hyaluronate 0.1%
In glycol 2%, the dilution of 10% water is added；
(3) ceteth -20 1%, flat walnut seed extract 6%, Butyrospermum parkii fruit fatty oil 0.8% and spermaceti is hard
Lipidol ethylhexoate 0.8% mixes, and is preheating to 85 °；
(4) mixed solution in step (1) after preheating is pumped into main cooker, then by the mixed solution after preheating in step (3)
It is pumped into main cooker, emulsifying, the control of homogenizer revolving speed simultaneously opens 25 turns/min of stirring in 3000 turns/min, homogeneous 8min, 85 °-
90 ° of heat preservation 25min, cooling；
(5) 40 ° are cooled in step (4), sequentially add solution in step (2) after dilution, dipotassium glycyrrhizinate 0.2%,
Long pubescence Chinese yam root extract 1%, dendrobium candidum extract 0.9%, Chinese walnut extract 0.9%, Herba Cancriniae lasiocarpae flower extract
1%, grape seed extract 1%, camellia flower extract 2%, arginine 1%, 1,2- hexylene glycol 1%, pasque flower extract
0.3%, long and thin hot pepper berry extract 0.3%, palpus extractive of usnea 0.3%, discharge after stirring 20min；
Material content is weight percentage in step (1)-(5).
Embodiment 2
A kind of peaceful dormancy essence cream is present embodiments provided, the essence cream component is according to weight percent are as follows: glycerol 5%, urine
Bursin 0.15%, glycine betaine 2%, carbomer 0.45%, butanediol 3%, glucose aminoglucan 1%, collagen 1%, caffeine
0.5%, Sodium Hyaluronate 0.1%, ceteth -20 2%, flat walnut seed extract 8%, Butyrospermum parkii fruit fatty oil 1%,
Cetostearyl alcohol ethylhexoate 1%, dipotassium glycyrrhizinate 0.25%, long pubescence Chinese yam root extract 1.2%, dendrobium candidum extract
Object 1%, Chinese walnut extract 1%, Herba Cancriniae lasiocarpae flower extract 1.25%, grape seed extract 1.2%, camellia flower extract
2.5%, arginine 1%, 1,2- hexylene glycol 1%, pasque flower extract 0.35%, long and thin hot pepper berry extract 0.35% must pine
Trailing plants extract 0.35%, the water of surplus.
The present embodiment additionally provides a kind of preparation method of peaceful dormancy essence cream, specifically:
(1) glycerol 5%, allantoin 0.15%, glycine betaine 2%, the water of carbomer 0.45% and 53.35% are mixed, preheating
To 90 °；
(2) fourth two is dispersed by glucose aminoglucan 1%, collagen 1%, caffeine 0.5% and Sodium Hyaluronate 0.1%
In alcohol 3%, the dilution of 10% water is added；
(3) by ceteth -20 2%, flat walnut seed extract 8%, Butyrospermum parkii fruit fatty oil 1% and cetearyl alcohol
Alcohol ethylhexoate 1% mixes, and is preheating to 90 °；
(4) mixed solution in step (1) after preheating is pumped into main cooker, then by the mixed solution after preheating in step (3)
It is pumped into main cooker, emulsifying, the control of homogenizer revolving speed simultaneously opens 25 turns/min of stirring in 3000 turns/min, homogeneous 8min, 85 °-
90 ° of heat preservation 30min, cooling；
(5) 42 ° are cooled in step (4), sequentially add solution in step (2) after dilution, dipotassium glycyrrhizinate 0.25%,
Long pubescence Chinese yam root extract 1.2%, dendrobium candidum extract 1%, Chinese walnut extract 1%, Herba Cancriniae lasiocarpae flower extract
1.25%, grape seed extract 1.2%, camellia flower extract 2.5%, arginine 1%, 1,2- hexylene glycol 1%, pasque flower
Extract 0.35%, long and thin hot pepper berry extract 0.35%, palpus extractive of usnea 0.35%, discharge after stirring 20min；
Material content is weight percentage in step (1)-(5).
Embodiment 3
A kind of peaceful dormancy essence cream is present embodiments provided, the essence cream component is according to weight percent are as follows: glycerol 6%, urine
Bursin 0.2%, glycine betaine 3%, carbomer 0.5%, butanediol 4%, glucose aminoglucan 1.5%, collagen 2%, caffeine
0.8%, Sodium Hyaluronate 0.15%, ceteth -20 3%, flat walnut seed extract 10%, Butyrospermum parkii fruit fatty oil
1.2%, cetostearyl alcohol ethylhexoate 1.2%, dipotassium glycyrrhizinate 0.3%, long pubescence Chinese yam root extract 1.5%, iron sheet
Herba Dendrobii extract 1.5%, Chinese walnut extract 1.5%, Herba Cancriniae lasiocarpae flower extract 1.5%, grape seed extract 1.5%, camellia
Flower extract 3%, arginase 12 %, 1,2- hexylene glycol 2%, pasque flower extract 0.4%, long and thin hot pepper berry extract 0.4%,
Palpus extractive of usnea 0.4%, the water of surplus.
The present embodiment additionally provides a kind of preparation method of peaceful dormancy essence cream, specifically:
(1) glycerol 6%, allantoin 0.2%, glycine betaine 3%, the water of carbomer 0.5% and 40.45% are mixed, is preheating to
90°；
(2) it disperses glucose aminoglucan 1.5%, collagen 2%, caffeine 0.8% and Sodium Hyaluronate 0.15% in
In butanediol 4%, the dilution of 10% water is added；
(3) ceteth -20 3%, flat walnut seed extract 10%, Butyrospermum parkii fruit fatty oil 1.2% and spermaceti is hard
Lipidol ethylhexoate 1.2% mixes, and is preheating to 90 °；
(4) mixed solution in step (1) after preheating is pumped into main cooker, then by the mixed solution after preheating in step (3)
It is pumped into main cooker, emulsifying, the control of homogenizer revolving speed simultaneously opens 25 turns/min of stirring in 3000 turns/min, homogeneous 8min, 85 °-
90 ° of heat preservation 35min, cooling；
(5) 45 ° are cooled in step (4), sequentially add solution in step (2) after dilution, dipotassium glycyrrhizinate 0.3%,
Long pubescence Chinese yam root extract 1.5%, dendrobium candidum extract 1.5%, Chinese walnut extract 1.5%, Herba Cancriniae lasiocarpae flower extract
1.5%, grape seed extract 1.5%, camellia flower extract 3%, arginase 12 %, 1,2- hexylene glycol 2%, pasque flower mention
Object 0.4%, long and thin hot pepper berry extract 0.4%, palpus extractive of usnea 0.4% are taken, is discharged after stirring 30min；
Material content is weight percentage in step (1)-(5).
Comparative example 1
According to embodiment 1, essence cream component does not add flat walnut seed extract, and the weight percent of water is changed to 77%,
Yu Jun is same as Example 1.
In addition to not adding flat walnut seed extract, in step (1), the weight percent of water is changed to the preparation method of essence cream
Outside 67%, remaining is same as Example 1.
Comparative example 2
According to embodiment 1, the weight percent of flat walnut seed extract is changed to 3% in essence cream component, the weight hundred of water
Ratio is divided to be changed to 74%, remaining is same as Example 1.
The preparation method of essence cream is changed to the weight of water in 3%, step (1) in addition to the weight percent of flat walnut seed extract
Amount percentage is changed to outside 64%, remaining is same as Example 1.
Comparative example 3
According to embodiment 1, the weight percent of flat walnut seed extract is changed to 12% in essence cream component, the weight hundred of water
Ratio is divided to be changed to 65%, remaining is same as Example 1.
The preparation method of essence cream is changed to the weight of water in 3%, step (1) in addition to the weight percent of flat walnut seed extract
Amount percentage is changed to outside 55%, remaining is same as Example 1.
Comparative example 4
According to embodiment 1, essence cream component does not add Chinese walnut extract, and the weight percent of water is changed to 71.9%,
Yu Jun is same as Example 1.
In addition to not adding, addition Chinese walnut extract, the weight percent of water changes the preparation method of essence cream in step (1)
Outside 61.9%, remaining is same as Example 1.
Comparative example 5
According to embodiment 1, essence cream component does not add camellia flower extract, and the weight percent of water is changed to 73%, remaining
It is same as Example 1.
In addition to not adding camellia flower extract, in step (1), the weight percent of water is changed to the preparation method of essence cream
Outside 63%, remaining is same as Example 1.
Comparative example 6
According to embodiment 1, the weight percent of camellia flower extract is changed to 1% in essence cream component, the weight percent of water
Than being changed to 70%, remaining is same as Example 1.
The preparation method of essence cream is changed to the weight of water in 1%, step (1) in addition to the weight percent of camellia flower extract
Percentage is changed to outside 60%, remaining is same as Example 1.
Comparative example 7
According to embodiment 1, the weight percent of camellia flower extract is changed to 4.5% in essence cream component, the weight hundred of water
Ratio is divided to be changed to 68.5%, remaining is same as Example 1.
The preparation method of essence cream is changed to the weight of water in 4.5%, step (1) in addition to the weight percent of camellia flower extract
Amount percentage is changed to outside 58.5%, remaining is same as Example 1.
Comparative example 8
According to embodiment 1, essence cream component does not add long pubescence Chinese yam root extract, and the weight percent of water is changed to
72%, remaining is same as Example 1.
The preparation method of essence cream in addition to not adding long pubescence Chinese yam root extract, in step (1) water weight percent
It is changed to outside 62%, remaining is same as Example 1.
Comparative example 9
According to embodiment 1, essence cream component does not add dendrobium candidum extract, and the weight percent of water is changed to 71.9%,
Remaining is same as Example 1.
In addition to not adding dendrobium candidum extract, in step (1), the weight percent of water is changed to the preparation method of essence cream
Outside 61.9%, remaining is same as Example 1.
Comparative example 10
According to embodiment 1, essence cream component does not add Herba Cancriniae lasiocarpae flower extract, and the weight percent of water is changed to 72%,
Yu Jun is same as Example 1.
In addition to not adding Herba Cancriniae lasiocarpae flower extract, in step (1), the weight percent of water is changed to the preparation method of essence cream
Outside 62%, remaining is same as Example 1.
Comparative example 11
According to embodiment 1, essence cream component does not add grape seed extract, and the weight percent of water is changed to 72%, remaining
It is same as Example 1.
In addition to not adding grape seed extract, in step (1), the weight percent of water is changed to the preparation method of essence cream
Outside 62%, remaining is same as Example 1.
Comparative example 12
According to Chinese patent CN109758520A, this comparative example provides a kind of compound essential oil with anti-insomnia effect, should
Essential oil is according to parts by weight by 5 parts of Rosa Damascanas, 5 parts of flores aurantii essential oils, 5 parts of absolute of jasmines, 3 parts of Flos Osmanthi Fragrantis quintessence oils, 3 parts remote sweet osmanthus essence
Oil, 3 parts of bergamot essential oils, 2 parts of lemons, 2 parts of Peppermint essential oils, 1.2 parts of Chinese ilex essential oils, 1.5 parts of rose pelargonium essential oils, 2
Part Rosemary Oil, 2 parts of deodar essential oils, 1 part of sandalwood essential oil, 4.5 parts of linalools, 3 parts of acetic acid lavender esters and 4 parts of benzyl carbinols,
0.5 part of angelica essential oil, 0.8 part of styrax, 0.7 part of olibanum, 0.6 part of Myrrha extract and 0.7 part of Notogineng Extract, 0.3 part of river
Rhizome of chuanxiong essential oil, 0.2 part of safflower essential oil, 0.5 part of rhizoma nardostachyos essential oil and 0.5 part of Rhizoma Paridis extract, 15 parts of glycerol, 30 portions of edible alcohols,
20 parts of part pure water mixed preparings form, and specific preparation method is identical as Chinese patent CN109758520A embodiment 1.
Treatment insomnia effect, anti-is carried out to compound essential oil in essence cream in embodiment 1-3 and comparative example 1-11, comparative example 12
Decline compact skin whitening measure of merit.
300 volunteers's (each half of men and women) 20~65 years old with insomnia situation are selected, wherein intractable aypnia (the course of disease 5
Year~20 years) 150 people, have a sleepless night (course of disease 6 months~1 year) 150 people in the recent period, and has 150 to have microgroove in 300 volunteers,
Volunteer sleeps preceding 1h clear water cleaning face and ears and smears face, ears behind, front and back ear behind, after the ear-lobe of front and back using product
It hangs down, is used continuously 2 months, during which do not use other products, insomnia situation is shown in Table 1, and removal microgroove, skin be compact and whitening situation
2 are shown in Table, wherein whitening situation is given a mark, and best result 5 divides, and minimum point 1 point, is averaged.
Table 1
As shown in Table 1, essence cream has good treatment for insomnia in embodiment 1-3, and therapeutic effect compares comparative example
Product is good in 1-12.When essence cream does not add the additive amount of flat walnut seed extract or flat walnut seed extract not in model of the present invention
In enclosing, the effect for the treatment of insomnia is decreased obviously.When essence cream does not add adding for camellia flower extract or camellia flower extract
Not within the scope of the present invention, the effect for the treatment of insomnia is substantially reduced dosage.When essence cream does not add Chinese walnut extract, control
It is also bad to treat insomnia effect.It can be seen that flat walnut seed extract, camellia flower extract, Chinese walnut extract in essence cream component
The combination of object can make one to go to sleep peacefully with antitoxic heart-soothing and sedative, keeping tensions down mood, have peaceful dormancy effect well.In comparative example 12
Essential oil treatment insomnia effect it is also bad.
Table 2
As shown in Table 2, in embodiment 1-3 essence cream removal microgroove effect, skin tightening effect and whitening effect all compared with
It is good.Camellia flower extract, long pubescence Chinese yam root extract, the Herba Cancriniae lasiocarpae flower that additive amount was not added or reduced to essence cream component extract
Object, grape seed extract, camellia flower extract, remove microgroove situation and the compact situation of skin is bad, it can be seen that, essence
The addition or reduction of these substances have an impact for removal microgroove situation, the compact situation of skin in white component, to illustrate
The combination of these substances directly affects removal microgroove effect and skin tightening effect.And flat walnut seed extract, Chinese walnut mention
Object, camellia flower extract, long pubescence Chinese yam root extract, dendrobium candidum extract is taken not to add or reduce additive amount, all
Can make the whitening effect of essence cream reduces, and illustrates that the combination of these substances directly affects the whitening effect of essence cream.Comparative example
Essential oil removal microgroove effect, skin tightening effect and whitening effect in 12 is bad.
Claims (7)
1. a kind of peaceful dormancy essence cream, which is characterized in that the essence cream component includes: glycerol 4~6% according to weight percent,
Allantoin 0.1~0.2%, glycine betaine 2~3%, carbomer 0.4~0.5%, butanediol 2~4%, glucose aminoglucan 0.8
~1.5%, collagen 1~2%, caffeine 0.1~0.8%, Sodium Hyaluronate 0.1~0.15%, ceteth -20 1~
3%, flat walnut seed extract 6~10%, Butyrospermum parkii fruit fatty oil 0.8~1.2%, cetostearyl alcohol ethylhexoate 0.8~
1.2%, dipotassium glycyrrhizinate 0.2~0.3%, long pubescence Chinese yam root extract 1~1.5%, dendrobium candidum extract 0.9~
1.5%, Chinese walnut extract 0.9~1.5%, Herba Cancriniae lasiocarpae flower extract 1~1.5%, grape seed extract 1~1.5%, camellia
Flower extract 2~3%, 1~2%, 1,2- hexylene glycol 1~2% of arginine, pasque flower extract 0.3~0.4%, long and thin hot pepper
Berry extract 0.3~0.4%, palpus extractive of usnea 0.3~0.4%, the water of surplus.
2. essence cream according to claim 1, which is characterized in that the essence cream component includes: sweet according to weight percent
Oil 4%, allantoin 0.1%, glycine betaine 2%, carbomer 0.4%, butanediol 2%, glucose aminoglucan 0.8%, collagen
1%, caffeine 0.1%, Sodium Hyaluronate 0.1%, ceteth -20 1%, flat walnut seed extract 6%, Butyrospermum parkii
Fruit fatty oil 0.8%, cetostearyl alcohol ethylhexoate 0.8%, dipotassium glycyrrhizinate 0.2%, long pubescence Chinese yam root extract 1%,
Dendrobium candidum extract 0.9%, Chinese walnut extract 0.9%, Herba Cancriniae lasiocarpae flower extract 1%, grape seed extract 1%, camellia
Flower extract 2%, arginine 1%, 1,2- hexylene glycol 1%, pasque flower extract 0.3%, long and thin hot pepper berry extract 0.3%,
Palpus extractive of usnea 0.3%, the water of surplus.
3. essence cream according to claim 1, which is characterized in that the essence cream component includes: sweet according to weight percent
Oil 5%, allantoin 0.15%, glycine betaine 2%, carbomer 0.45%, butanediol 3%, glucose aminoglucan 1%, collagen
1%, caffeine 0.5%, Sodium Hyaluronate 0.1%, ceteth -20 2%, flat walnut seed extract 8%, Butyrospermum parkii
Fruit fatty oil 1%, cetostearyl alcohol ethylhexoate 1%, dipotassium glycyrrhizinate 0.25%, long pubescence Chinese yam root extract 1.2%, iron
Skin Herba Dendrobii extract 1%, Chinese walnut extract 1%, Herba Cancriniae lasiocarpae flower extract 1.25%, grape seed extract 1.2%, camellia
Extract 2.5%, arginine 1%, 1,2- hexylene glycol 1%, pasque flower extract 0.35%, long and thin hot pepper berry extract
0.35%, palpus extractive of usnea 0.35%, the water of surplus.
4. essence cream according to claim 1, which is characterized in that the essence cream component includes: sweet according to weight percent
Oil 6%, allantoin 0.2%, glycine betaine 3%, carbomer 0.5%, butanediol 4%, glucose aminoglucan 1.5%, collagen
2%, caffeine 0.8%, Sodium Hyaluronate 0.15%, ceteth -20 3%, flat walnut seed extract 10%, butter fruit
Set fruit fatty oil 1.2%, cetostearyl alcohol ethylhexoate 1.2%, dipotassium glycyrrhizinate 0.3%, long pubescence Chinese yam root extract
1.5%, dendrobium candidum extract 1.5%, Chinese walnut extract 1.5%, Herba Cancriniae lasiocarpae flower extract 1.5%, grape seed extract
1.5%, camellia flower extract 3%, arginase 12 %, 1,2- hexylene glycol 2%, pasque flower extract 0.4%, prickly ash berries mentions
Take object 0.4%, palpus extractive of usnea 0.4%, the water of surplus.
5. a kind of preparation method of peaceful dormancy essence cream, comprising:
(1) by glycerol 4~6%, allantoin 0.1~0.2%, glycine betaine 2~3%, carbomer 0.4~0.5% and 30.45~
The mixing of 61% water, is preheating to 85 ° -90 °；
(2) by glucose aminoglucan 0.8~1.5%, collagen 1~2%, caffeine 0.1~0.8% and Sodium Hyaluronate 0.1
~0.15% is scattered in butanediol 2~4%, and the dilution of 10~20% water is added；
(3) by ceteth -20 1~3%, flat walnut seed extract 6~10%, Butyrospermum parkii fruit fatty oil 0.8~1.2%
It is mixed with cetostearyl alcohol ethylhexoate 0.8~1.2%, is preheating to 85 ° -90 °；
(4) mixed solution after preheating in step (1) is pumped into main cooker, then the mixed solution after preheating in step (3) is pumped into
Main cooker, emulsifying, stirring, 85 ° of -90 ° of heat preservations, cooling；
(5) 40~45 ° are cooled in step (4), the solution, dipotassium glycyrrhizinate 0.2 after sequentially adding the middle dilution of step (2)~
0.3%, long pubescence Chinese yam root extract 1~1.5%, dendrobium candidum extract 0.9~1.5%, Chinese walnut extract 0.9~
1.5%, Herba Cancriniae lasiocarpae flower extract 1~1.5%, grape seed extract 1~1.5%, camellia flower extract 2~3%, arginine 1
~2%, 1,2- hexylene glycol 1~2%, pasque flower extract 0.3~0.4%, long and thin hot pepper berry extract 0.3~0.4%, palpus pine
Trailing plants extract 0.3~0.4% discharges after stirring；
Material content is weight percentage in step (1)-(5).
6. method according to claim 5, which is characterized in that homogenizing time is 6~10min in the step (4)；When heat preservation
Between be 25~35min.
7. method according to claim 5, which is characterized in that mixing time is 20~30min in the step (5).
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112656932A (en) * | 2020-12-24 | 2021-04-16 | 东莞市容大生物科技有限公司 | Composition for regulating emotional factors and improving sub-health and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958228A (en) * | 2015-07-28 | 2015-10-07 | 上海贝泰妮生物科技有限公司 | Whitening and freckle-removing composite preparation and preparation method thereof |
| CN106265330A (en) * | 2016-08-29 | 2017-01-04 | 杭州千岛湖蓝色天使实业有限公司 | The cream that a kind of wrinkle removing is anti-ageing |
| CN108478460A (en) * | 2018-05-21 | 2018-09-04 | 杭州千岛湖蓝色天使实业有限公司 | Moisturizing essence cream and preparation method thereof |
| CN108514519A (en) * | 2018-05-11 | 2018-09-11 | 珠海伊斯佳科技股份有限公司 | A kind of skin care compositions and methods and its application method of whitening and anti-aging |
| CN108524357A (en) * | 2018-05-18 | 2018-09-14 | 广东盛美化妆品有限公司 | A kind of fresh and alive beautiful fine flour frost of the root extract containing Aplotaxis auriculata and preparation method thereof |
-
2019
- 2019-08-23 CN CN201910783710.9A patent/CN110339135A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958228A (en) * | 2015-07-28 | 2015-10-07 | 上海贝泰妮生物科技有限公司 | Whitening and freckle-removing composite preparation and preparation method thereof |
| CN106265330A (en) * | 2016-08-29 | 2017-01-04 | 杭州千岛湖蓝色天使实业有限公司 | The cream that a kind of wrinkle removing is anti-ageing |
| CN108514519A (en) * | 2018-05-11 | 2018-09-11 | 珠海伊斯佳科技股份有限公司 | A kind of skin care compositions and methods and its application method of whitening and anti-aging |
| CN108524357A (en) * | 2018-05-18 | 2018-09-14 | 广东盛美化妆品有限公司 | A kind of fresh and alive beautiful fine flour frost of the root extract containing Aplotaxis auriculata and preparation method thereof |
| CN108478460A (en) * | 2018-05-21 | 2018-09-04 | 杭州千岛湖蓝色天使实业有限公司 | Moisturizing essence cream and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 王建新 主编: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112656932A (en) * | 2020-12-24 | 2021-04-16 | 东莞市容大生物科技有限公司 | Composition for regulating emotional factors and improving sub-health and preparation method thereof |
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