CN110279807A - A kind of Chinese medicine composition and preparation method thereof for treating reflux esophagitis - Google Patents

A kind of Chinese medicine composition and preparation method thereof for treating reflux esophagitis Download PDF

Info

Publication number
CN110279807A
CN110279807A CN201910684036.9A CN201910684036A CN110279807A CN 110279807 A CN110279807 A CN 110279807A CN 201910684036 A CN201910684036 A CN 201910684036A CN 110279807 A CN110279807 A CN 110279807A
Authority
CN
China
Prior art keywords
parts
chinese medicine
reflux esophagitis
medicine composition
kapok
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910684036.9A
Other languages
Chinese (zh)
Inventor
张红参
黄海舸
卢波
窦锡彬
关皓邺
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
YOUJIANG NATIONAL MEDICAL COLLEGE
Original Assignee
YOUJIANG NATIONAL MEDICAL COLLEGE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by YOUJIANG NATIONAL MEDICAL COLLEGE filed Critical YOUJIANG NATIONAL MEDICAL COLLEGE
Priority to CN201910684036.9A priority Critical patent/CN110279807A/en
Publication of CN110279807A publication Critical patent/CN110279807A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese medicine composition and preparation method thereof for treating reflux esophagitis, the composition is made of according to mass parts following components: 2 parts -10 parts of kapok fourth, 2 parts -10 parts of the bletilla striata, 2 parts -10 parts of dandelion.The present invention is safe and effective, it is not damaged, its follow traditional Chinese medicine and modern medical theory, it verifies by clinic application, it can maintain effective, permanent treatment, prevent the high advantages such as without side-effects of Relapse rate and cure rate, and do not occur other side effects, total effective rate 91.7%, cure rate is up to 72.3%.

Description

A kind of Chinese medicine composition and preparation method thereof for treating reflux esophagitis
Technical field
The invention belongs to Chinese medicine composition development technique fields, specifically, being related to a kind of for treating reflux oesophagus Scorching Chinese medicine composition and preparation method thereof.
Background technique
Reflux esophagitis (Reflux Esophagitis, abbreviation RE), is commonly called as " heartburn disease ", belongs in disease of digestive tract Common disease, frequently-occurring disease refer to and cause gastroduodenal content reflux due to losing relaxation etc. digestive obstruetion, esophageal sphincter Enter oesophagus, alimentary canal liquid chemical stimulation causes damage caused by the breakage of oesophageal surface mucous membrane.Clinical signs go out heartburn sense, disappear Change road reflux, retrosternal pain etc., course of disease elder Chang Bingfa sphagitis, pneumonia, or even induce oesophagus cancerous lesion, seriously endangers The physical and mental health of patient.Western medicine is mostly symptomatic treatment, in the case that esophageal sphincter mistake speed equal Basic disease causes exist, easily appearance is more Still recurrent exerbation after secondary treatment is alleviated.Tcm treatment according to syndrome differentiation, have the effect of it is certain, but due to decocting for Chinese herbal medicine inconvenience, and taste Road is larger, and mouthfeel is bad, and patient is difficult to adhere to taking.RE generates the symptoms such as reflux since alimentary canal function goes wrong, and controls Therapeutic effect is short-term effectively, the state of an illness is easy the difficult point for recurring, needing Long-term taking medicine etc. and be all in treatment, how to remain effective, permanent Treatment, prevent Relapse rate from seeming and be even more important.
Summary of the invention
In view of this, the present invention is directed to above-mentioned problem, provide a kind of for treating the Chinese medicine group of reflux esophagitis Object and preparation method thereof is closed, according to traditional Chinese medicine modern pharmacological research and Modern medical therapy principle, dialectical based on disease is controlled Treating principle selects the suitable powder that is made of medicinal material compatibility to be taken orally, has the effect of clearing heat and eliminating phlegm, harmonizing stomach and lowering adverse Qi, removing blood stasis for promoting tissue regeneration, It controls outside interior tune, treatment method is easy, instructions of taking is convenient, therapeutic effect is significant, treatment reflux esophagitis without side-effects Interior tune external therapy combination.
In order to solve the above-mentioned technical problem, the invention discloses a kind of for treating the Chinese traditional medicine composition of reflux esophagitis Object is made of according to mass parts following components: 2 parts -10 parts of kapok fourth, 2 parts -10 parts of the bletilla striata, 2 parts -10 parts of dandelion.
Optionally, it is made of according to mass parts following components: 6 parts of kapok fourth, 6 parts of the bletilla striata, 6 parts of dandelion.
The invention also discloses a kind of for treating the preparation method of the Chinese medicine composition of reflux esophagitis, including following Step:
Step 1 weighs drug: weighing 2 parts -10 parts of kapok fourth, 2 parts -10 parts of the bletilla striata, dandelion according to above-mentioned mass parts 2 parts -10 parts;
Step 2, it washes solarization drug: the load weighted all medicine removing impurity of step 1 being cleaned, is dried;
Step 3, mixed grinding: most fine powder is ground into after all drugs are mixed;
Step 4, it weighs packing: the good fine powder of step 3 mixed grinding being weighed 5 grams 1 part, is respectively charged into 4*6cm composite membrane Filter paper tea bag sack seals spare.
Compared with prior art, the present invention can be obtained including following technical effect:
1) present invention it is safe and effective, not damaged, its follow traditional Chinese medicine and modern medical theory, verify by clinic application, It can maintain effective, permanent treatment, prevent the high advantages such as without side-effects of Relapse rate and cure rate, and do not occur other pairs Effect, total effective rate 91.7%, cure rate is up to 72.3%.
2) the present invention be directed to the symptoms such as heartburn sense, alimentary canal reflux, retrosternal pain caused by reflux esophagitis to control Therapeutic effect is significant.The party selects powder, and wherein kapok fourth and bletilla striata quality are sticky, easily adheres to esophageal mucosa membrane lesion, powder It takes orally after mixing evenly, can keep drug in the time of disease damage esophagus part to the maximum extent, reach optimal therapeutic effect. And it makes simply, it is low in cost, it has no toxic side effect, it is convenient to take, it is easy to carry.
Certainly, it implements any of the products of the present invention it is not absolutely required to while reaching all the above technical effect.
Specific embodiment
Carry out the embodiment that the present invention will be described in detail below in conjunction with embodiment, whereby to the present invention how application technology hand Section solves technical problem and reaches the realization process of technical effect to fully understand and implement.
The invention discloses a kind of for treating the Chinese medicine composition of reflux esophagitis, according to mass parts by following components It constitutes: 2 parts -10 parts of kapok fourth, 2 parts -10 parts of the bletilla striata, 2 parts -10 parts of dandelion.
Wherein, bletilla striata bitter, hardship can be dropped and let out, harmonizing stomach and lowering adverse Qi, therefore can effectively release diaphragmatic spasm and preventing or arresting vomiting stops oh;Puckery, Puckery to restrain, convergence can reduce swelling;Matter is glutinous, can promote inflammation ulcer healing;Modern chemistry research the bletilla striata contain volatile oil, starch, Lymphatic temperament, bletilla mannan and 5 kinds of antimicrobial compounds, clinic are used to treat digestive tract ulcer, local hemorrhage, esophagus, stomach hand Postoperative previous anastomotic inflammation, erosion etc., therapeutic effect is good.Dandelion bitter can be opened and be let out, and energy heat-clearing cold in nature has clearing heat and detoxicating, Li Shui The function of detumescence;Pharmacological research shows that it has inhibiting effect to various bacteria, fungi;Energy Hepatoprotective cholagogue, promotes bile secretion, To gastritis especially helicobacter pylori, inhibitory effect more preferably, and can rush down stomach fire, and gas is very flat, can purging intense heat do not damage soil again, therefore Can long-term, high-dose take, positive open fire moves back, and stomach Qi is spontaneous.Kapok fourth cold nature, acrid flavour, puckery, that chews has stickiness.Energy cold in nature is clear Heat, acrid flavour energy eliminating stasis to subdue swelling, shares with dandelion, reinforces clearing heat and detoxicating, the function of inducing diuresis for removing edema;Puckery can restrain, and that chews has Stickiness, containing colloidal ingredient, the bletilla striata sticked with matter is shared, and so that impaired mucous membrane surface is formed one layer of periosteum good adsorption work again With, so that drug is directly acted on oesophagus, stomach, mucous membrane, thus reduce oesophagus gastric mucosa congestion, oedema and stop blooding it is non-return, thus plus It is strong to promote wound granulation growth and healing.
The party selects powder, and wherein kapok fourth and bletilla striata quality are sticky, easily adheres to esophageal mucosa membrane lesion, powder stirring It is oral after uniformly, it can keep drug in the time of disease damage esophagus part to the maximum extent, reach optimal therapeutic effect.
The invention also discloses a kind of for treating the preparation method of the Chinese medicine composition of reflux esophagitis, including following Step:
Step 1 weighs drug: weighing following components: 2 parts -10 parts of kapok fourth, 2 parts -10 parts of the bletilla striata, Pu according to mass parts 2 parts -10 parts of public English;
Step 2, it washes solarization drug: the load weighted all medicine removing impurity of step 1 being cleaned, is dried;
Step 3, mixed grinding: most fine powder is ground into after all drugs are mixed.
Step 4, it weighs packing: the good fine powder of step 3 mixed grinding being weighed 5 grams 1 part, is respectively charged into 4*6cm composite membrane Filter paper tea bag sack seals spare.
When specifically used, daily 1 bag, with sack is opened, medicinal powder poured out, is taken after mixing it with water with warm water, three times a day.
Embodiment 1
It is a kind of for treating the Chinese medicine composition of reflux esophagitis, be made of according to mass parts following components: kapok fourth 6 Part, 6 parts of the bletilla striata, 6 parts of dandelion.
Above-mentioned composition the preparation method is as follows:
Step 1 weighs drug: weighing kapok fourth, the bletilla striata and dandelion according to above-mentioned mass parts;
Step 2, it washes solarization drug: the load weighted all medicine removing impurity of step 1 being cleaned, is dried;
Step 3, mixed grinding: most fine powder is ground into after all drugs are mixed.
Step 4, it weighs packing: the good fine powder of step 3 mixed grinding being weighed 5 grams 1 part, is respectively charged into 4*6cm composite membrane Filter paper tea bag sack seals spare.
When specifically used, daily 1 bag, with sack is opened, medicinal powder poured out, is taken after mixing it with water with warm water, three times a day.
When in use, cooperate catgut implantation at acupoint: Tiantu, large intestine merdianIt is double, the middle part of gastric cavity, kan shuIt is double, QimenIt is double, rush very muchIt is double
It is the essence under traditional Chinese medicine modern pharmacological research and modern medical theory guidance that external therapy combination is adjusted in of the invention Acupuncture point and medicament composing prescription are selected, is controlled outside interior tune, treatment reflux esophagitis curative effect is high, has no toxic side effect.Outer treatment is adjusted in of the invention In method, catgut implantation at acupoint: Tiantu: local point selection, go directly part oesophagus, adjusts mechanism of qi, dredges local qi and blood;Large intestine merdian, the middle part of gastric cavity and liver Yu, Qimen: two groups of Yu the Mu-front acupoints matching liver stomaches reinforce the easypro liver normalizing the stomach by guiding QI downward effect of qi-regulating with controlling, with ether punching;Ke shu is that blood understands it Cave stimulates ke shu blood circulation promoting nourishes blood, wide chest stomach function regulating;Zusanli is the lower confluent point of stomach meridian, can relieving QI stagnancy in the stomach, recuperating qi-blood, all caves is closed With, clear syndrome of liver-stomach heat, chest qi, activating microcirculation and removing stasis medicinal, harmonizing stomach and lowering adverse Qi.
Embodiment 2
It is a kind of for treating the Chinese medicine composition of reflux esophagitis, be made of according to mass parts following components: kapok fourth 2 Part, 10 parts of the bletilla striata, 2 parts of dandelion.
Above-mentioned composition the preparation method is as follows:
Step 1 weighs drug: weighing kapok fourth, the bletilla striata and dandelion according to above-mentioned mass parts;
Step 2, it washes solarization drug: the load weighted all medicine removing impurity of step 1 being cleaned, is dried;
Step 3, mixed grinding: most fine powder is ground into after all drugs are mixed.
Step 4, it weighs packing: the good fine powder of step 3 mixed grinding being weighed 5 grams 1 part, is respectively charged into 4*6cm composite membrane Filter paper tea bag sack seals spare.
When specifically used, daily 1 bag, with sack is opened, medicinal powder poured out, is taken after mixing it with water with warm water, three times a day.
Embodiment 3
It is a kind of for treating the Chinese medicine composition of reflux esophagitis, be made of according to mass parts following components: kapok fourth 10 parts, 2 parts of the bletilla striata, 10 parts of dandelion.
Above-mentioned composition the preparation method is as follows:
Step 1 weighs drug: weighing kapok fourth, the bletilla striata and dandelion according to above-mentioned mass parts;
Step 2, it washes solarization drug: the load weighted all medicine removing impurity of step 1 being cleaned, is dried;
Step 3, mixed grinding: most fine powder is ground into after all drugs are mixed.
Step 4, it weighs packing: the good fine powder of step 3 mixed grinding being weighed 5 grams 1 part, is respectively charged into 4*6cm composite membrane Filter paper tea bag sack seals spare.
When specifically used, daily 1 bag, with sack is opened, medicinal powder poured out, is taken after mixing it with water with warm water, three times a day.
Illustrate technical effect of the invention below with reference to specific experimental data:
One, diagnostic criteria:
The present invention be used to treat the Chinese medicine composition of reflux esophagitis for observe it is all be diagnosed as reflux esophagitis and Clinical manifestation is heartburn, sour regurgitation, belch, retrosternal pain are main symptom, red tongue with yellowish fur, the case of wiry and frequent pulse.
Two, treatment method:
Random grouping own control comparison method is taken, the variation of patient's pretherapy and post-treatment symptom, sign and result is compared.
When specifically used, daily 1 bag, with sack is opened, medicinal powder poured out, is taken after mixing it with water with warm water, three times a day.During taking: Even served January is a period, and March is as a treatment course.Medication taboo: avoiding eating the irritable foods such as raw and cold, pungent, tobacco and wine and scalds drink excessively Food;It cannot lie down within 2 hours after meal, no longer be fed after supper;Keep mood comfortable.
Three, criterion of therapeutical effect:
1. curing: clinical symptoms disappear;
2. effective: medication control, recurrence period are reduced, and symptom mitigates;
3. effectively: symptom mitigates;
4. invalid: symptom is without substantially changeing.
Four, treatment results
After after 3 menstrual cycles, using the treatment method in embodiment 1, and the patient of 1 traditional Chinese medicinal components of embodiment is taken, Total effective rate 91.7%, cure rate is up to 72.3%.
Above description has shown and described several preferred embodiments of invention, but as previously described, it should be understood that invention is not It is confined to form disclosed herein, should not be regarded as an exclusion of other examples, and can be used for various other combinations, modification And environment, and can be carried out within that scope of the inventive concept describe herein by the above teachings or related fields of technology or knowledge Change.And changes and modifications made by those skilled in the art do not depart from the spirit and scope of invention, then it all should be in the appended power of invention In the protection scope that benefit requires.

Claims (3)

1. a kind of for treating the Chinese medicine composition of reflux esophagitis, which is characterized in that according to mass parts by following components structure At: 2 parts -10 parts of kapok fourth, 2 parts -10 parts of the bletilla striata, 2 parts -10 parts of dandelion.
2. according to claim 1 for treating the Chinese medicine composition of reflux esophagitis, which is characterized in that according to quality Part is made of following components: 6 parts of kapok fourth, 6 parts of the bletilla striata, 6 parts of dandelion.
3. a kind of for treating the preparation method of the Chinese medicine composition of reflux esophagitis, which comprises the following steps:
Step 1 weighs drug: weighing 2 parts -10 parts of kapok fourth, 2 parts -10 parts of the bletilla striata, 2 parts of dandelion-according to above-mentioned mass parts 10 parts;
Step 2, it washes solarization drug: the load weighted all medicine removing impurity of step 1 being cleaned, is dried;
Step 3, mixed grinding: most fine powder is ground into after all drugs are mixed;
Step 4, it weighs packing: the good fine powder of step 3 mixed grinding being weighed 5 grams 1 part, is respectively charged into the filtering of 4*6cm composite membrane Paper bag is made tea sack, is sealed spare.
CN201910684036.9A 2019-07-26 2019-07-26 A kind of Chinese medicine composition and preparation method thereof for treating reflux esophagitis Pending CN110279807A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910684036.9A CN110279807A (en) 2019-07-26 2019-07-26 A kind of Chinese medicine composition and preparation method thereof for treating reflux esophagitis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910684036.9A CN110279807A (en) 2019-07-26 2019-07-26 A kind of Chinese medicine composition and preparation method thereof for treating reflux esophagitis

Publications (1)

Publication Number Publication Date
CN110279807A true CN110279807A (en) 2019-09-27

Family

ID=68024092

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910684036.9A Pending CN110279807A (en) 2019-07-26 2019-07-26 A kind of Chinese medicine composition and preparation method thereof for treating reflux esophagitis

Country Status (1)

Country Link
CN (1) CN110279807A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106924539A (en) * 2017-03-23 2017-07-07 湖北工业大学 A kind of Chinese medicine preparation for treating peptic ulcer, gastritis and reflux esophagitis and its preparation method and application
CN108743805A (en) * 2018-08-20 2018-11-06 熊学荣 A kind of Chinese medicine composition and preparation method thereof for treating reflux gastritis, esophagitis and epithelial metaplasia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106924539A (en) * 2017-03-23 2017-07-07 湖北工业大学 A kind of Chinese medicine preparation for treating peptic ulcer, gastritis and reflux esophagitis and its preparation method and application
CN108743805A (en) * 2018-08-20 2018-11-06 熊学荣 A kind of Chinese medicine composition and preparation method thereof for treating reflux gastritis, esophagitis and epithelial metaplasia

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘有缘: "《一两味中药祛顽疾》", 31 August 2016, 山西科学技术出版社 *
吴琳玲: "《健康养胃必知的生活细节大全》", 30 June 2013, 天津科学技术出版社 *

Similar Documents

Publication Publication Date Title
CN110227117A (en) It is a kind of to treat osteoproliferation, pharmaceutical composition of lumbocrural pain and preparation method thereof
CN110279807A (en) A kind of Chinese medicine composition and preparation method thereof for treating reflux esophagitis
CN103816421A (en) Traditional Chinese medicine preparation for treating reflux esophagitis and preparation method thereof
CN101991804B (en) Externally applied medicament for treating stomach illness
CN1097461C (en) Paste for treating child diarrhoea
CN108721504A (en) A kind of traditional Chinese medicine for oral administration for treating chronic gastritis
CN105998551A (en) Traditional Chinese medicine composition for treating stomachache and preparation method thereof
CN104998041A (en) Traditional Chinese medicine composition for curing gastric ulcer of Chinese internal medicine
CN1073437C (en) Chinese medicine for treating digestive tract inflammation and ulcer
CN105168594A (en) Traditional Chinese medicine for treating gastric ulcer
CN107412678A (en) A kind of new medicine composition for treating diabetes and preparation method thereof
CN107970429A (en) A kind of Chinese patent drug oral formulations for promoting postoperative gastroenteritic power functional rehabilitation
CN107441477A (en) A kind of oral liquid for treating stomach paralysis and preparation method thereof
CN106620348A (en) Unguent for treating scald, bedsore and haemorrhoids
CN106266369A (en) Anti-inflammatory analgetic dredges strongly fragrant soup
CN104958688A (en) Chinese medicinal preparation for treating gastroesophageal reflux disease and preparation method thereof
CN105943955A (en) Traditional Chinese medicine preparation for treating gastric ulcer and preparation method thereof
CN105106664A (en) Traditional Chinese medicine decoction for treating chronic erosive gastritis and preparation method thereof
CN107375603A (en) A kind of capsule medicine for treating chronic gastritis and preparation method thereof
CN105597050A (en) Acupuncture point pasting medicine for treating and preventing chemotherapy-induced vomiting
CN104815277A (en) Traditional Chinese medicine for treating gastric stone
CN104800352A (en) Traditional Chinese medicine for treating infantile anorexia
CN1156291C (en) Mihaigao ointment made of honey, sepium and other traditional Chinese medicine and its prepn.
CN107519446A (en) A kind of decoction medicine for treating duodenal ulcer and preparation method thereof
CN107753825A (en) A kind of Chinese medicine composition for treating pathogenic cold stomach invading type stomach trouble

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20190927