CN110279802A - A kind of Chinese herbal medicine formula that treating diabetes and its preparation and application - Google Patents

A kind of Chinese herbal medicine formula that treating diabetes and its preparation and application Download PDF

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Publication number
CN110279802A
CN110279802A CN201910619879.0A CN201910619879A CN110279802A CN 110279802 A CN110279802 A CN 110279802A CN 201910619879 A CN201910619879 A CN 201910619879A CN 110279802 A CN110279802 A CN 110279802A
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parts
chinese herbal
herbal medicine
medicine formula
diabetes
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陈辉球
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Zhuhai Hantang Biotechnology Engineering Co Ltd
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Zhuhai Hantang Biotechnology Engineering Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to field of Chinese herbal, espespecially a kind of Chinese herbal medicine formula for treating diabetes and its preparation and application.The Chinese herbal medicine formula that the present invention treats diabetes can steadily reduce blood glucose and effectively control blood glucose, moreover it is possible to enhance human immunity, improve hyperglycemia and diabetic constitution.Take preparation prepared by Chinese herbal medicine formula of the present invention for a long time, damaged islet cells can be effectively repaired, insulin resistance is mitigated, improve the circulation of pancreas blood, improve pancreas blood supply deficiency, accelerates the transformation of islet function and cell that sugar is absorbed and utilized.

Description

A kind of Chinese herbal medicine formula that treating diabetes and its preparation and application
Technical field
The present invention relates to field of Chinese herbal, espespecially a kind of Chinese herbal medicine formula for treating diabetes and its preparation and application.
Background technique
Diabetes be it is a kind of due to blood glucose is out of control, be higher by normal level caused by systemic disease, suffer from diabetes when, Long-standing hyperglycemia will lead to the various tissue nerve damages such as eye, kidney, heart, blood vessel and dysfunction, so as to cause Various diabetes de-velopments.Its complication is more and serious, and illness rate gradually increases in China.With the development of production, living standard It improves and the extension of population life, diabetes morbidity increases rapidly, it has also become an increasingly severe prevalence of countries in the world Property disease.
Many people think that diabetes only pass through doctor trained in Western medicine just and can delay disease and continue to develop.But it is seen according to Long-term clinical It examines, many diabetic's early stages take various chemically Western medicine, and blood glucose can quickly decline, and this decline is temporary With ignore the possible consequences, be enough that human nutrition is blocked to be absorbed as cost, generate very big injury and side effect to body in drug In the case of generate, treatment results can all face is gradually increased drug dose, constantly changes and takes various drugs, until drug occurs The embarrassment of failure;Not only aforesaid way cannot make islet function restore normally steadily to decline with blood glucose, and side effects of pharmaceutical drugs are in machine Body is put aside for a long time, also results in the bigger injury of body.
Summary of the invention
To solve the above problems, the present invention provides a kind of Chinese herbal medicine formula for treating diabetes, blood glucose can be steadily reduced With effective control blood glucose.
To achieve the above object, the technical solution adopted by the present invention is that: a kind of Chinese herbal medicine formula for treating diabetes, each original The parts by weight of material are respectively as follows: 5-8 parts of pueraria lobata, 8-10 parts of rhizoma polygonati, 5-8 parts of dark plum, 8-12 parts of cassia seed, 3-5 parts of Chinese yam, Radix Glycyrrhizae 1- 2 parts, bitter 3-8 parts of mulberry leaf, 40-50 parts of sweet wormwood, 8-15 parts of Herba Euphorbiae Humifusae.
Specifically, the parts by weight of each raw material are respectively as follows: 8 parts of pueraria lobata, 10 parts of rhizoma polygonati, 10 parts of dark plum, 10 parts of cassia seed, Chinese yam 5 parts, 2 parts of Radix Glycyrrhizae, bitter 5 parts of mulberry leaf, 40 parts of sweet wormwood, 10 parts of Herba Euphorbiae Humifusae.
The present invention also provides a kind of preparations of above-mentioned treatment diabetes Chinese herbal medicine formula, will using existing Chinese medicine preparation method Capsule, tablet or electuary is made in the Chinese herbal medicine formula of above-mentioned treatment diabetes.
Wherein, capsule, tablet or electuary made of pharmaceutically acceptable auxiliary material is added in the Chinese herbal medicine.
The present invention also provides a kind of application of the Chinese herbal medicine formula of above-mentioned treatment diabetes, the medium-height grass of the treatment diabetes Medicine composition reduces the application in hypoglycemic medicament in preparation.
The beneficial effects of the present invention are: the Chinese herbal medicine formula that the present invention treats diabetes can steadily reduce blood glucose and have Effect control blood glucose, moreover it is possible to enhance human immunity, improve hyperglycemia and diabetic constitution.Take Chinese herbal medicine of the present invention for a long time The prepared preparation of formula, can effectively repair damaged islet cells, mitigate insulin resistance, improve the circulation of pancreas blood, Improve pancreas blood supply deficiency, accelerates the transformation of islet function and cell that sugar is absorbed and utilized.
Specific embodiment
Below by specific embodiment, invention is further described in detail.The application can be with a variety of different Form is realized, however it is not limited to embodiment described in the present embodiment.The purpose for providing following specific embodiments is easy for Thorough explanation is become apparent to present disclosure.
Embodiment one
A kind of Chinese herbal medicine formula for treating diabetes, the parts by weight of each raw material are respectively as follows: 8 parts of pueraria lobata, 10 parts of rhizoma polygonati, dark plum 10 Part, 10 parts of cassia seed, 5 parts of Chinese yam, 2 parts of Radix Glycyrrhizae, bitter 5 parts of mulberry leaf, 40 parts of sweet wormwood, 10 parts of Herba Euphorbiae Humifusae.
Embodiment two
A kind of Chinese herbal medicine formula for treating diabetes, the parts by weight of each raw material be respectively as follows: 5 parts of pueraria lobata, 8 parts of rhizoma polygonati, 6 parts of dark plum, 10 parts of cassia seed, 4 parts of Chinese yam, 2 parts of Radix Glycyrrhizae, bitter 5 parts of mulberry leaf, 45 parts of sweet wormwood, 10 parts of Herba Euphorbiae Humifusae.
The present embodiment also protects the preparation of above-mentioned treatment diabetes Chinese herbal medicine formula, will be upper using existing Chinese medicine preparation method Capsule, tablet or electuary is made in the Chinese herbal medicine formula for stating treatment diabetes;And pharmaceutically acceptable auxiliary material can be added It is made, for example water is added, beverage is made.
The present invention also protects the application of the Chinese herbal medicine formula of above-mentioned treatment diabetes, specially treats the Chinese herbal medicine of diabetes Being formulated reduces the application in hypoglycemic medicament in preparation.
In the present embodiment, the Chinese herbal medicine formula drug of above-mentioned treatment diabetes the preparation method is as follows: firstly, first will It cleaned, dried and is sterilized in raw material, and is dry to water content≤4%;Then, each raw material is mixed by weight, and It is crushed with Roughpulverizer;Raw material after coarse crushing is pulverized to obtain micropowders again;Finally cooperate warm water It takes, three times per day.Further, it is also possible to which capsule, compression is made in flakes in the micropowders using existing preparation method Agent is dried to electuary, and this is not restricted.
The preparation method of the present embodiment improves the validity of drug in the case where keeping medicinal material not to be destroyed as far as possible.Continuously It takes drug of the present invention three months or more, can steadily reduce blood glucose and effectively control blood glucose, moreover it is possible to enhance human immunity, change Kind hyperglycemia and diabetic constitution.Take preparation prepared by Chinese herbal medicine formula of the present invention for a long time, can effectively repair by Islet cells is damaged, insulin resistance is mitigated, improves the circulation of pancreas blood, and the drug is without any toxicity and side effects;It can also improve thin Born of the same parents' quality promotes function of human body, improves pancreas blood supply deficiency, and the transformation for accelerating islet function and cell are to sugar It is absorbed and utilized.
It should be noted that drug of the present invention is not suitable for infant, strong tea should not be drunk when taking, and should not also take it His temperaturing injecting-ability Chinese medicine.
The raw material selection of the present embodiment is as follows:
Pueraria lobata: it is dry, sweet, pungent, it is cool.There is expelling pathogenic factors from muscles and skin to bring down a fever, promoting eruption, promote the production of body fluid to quench thirst, the function of Shengyang Zhixie.Be usually used in exterior syndrome fever, Stiff nape and back, measles without adequate eruption, pyreticosis are thirsty, the deficiency of Yin is quenched one's thirst, heat is purged heat dysentery, splenasthenic diarrhea.
Rhizoma polygonati: rhizome it is horizontal walk, cylindric, tubercle expands.Impeller generator, stockless.Medicinal plant has tonifying spleen, moistening lung and producing body fluid Effect.
The effect of dark plum: having astringing lung-QI, and puckery intestines promote the production of body fluid, claming ascaris.It is usually used in chronic cough of deficiency lung, protracted dysentery and diarrhea, abnormal heat is quenched one's thirst, The ascariasis of biliary tract vomits abdominal pain.
Cassia seed: bitter, sweet, salty, cold nature enters liver, kidney, large intestine channel;Relax bowel and defecation, lipid-loweringing improving eyesight, treat constipation and Hyperlipidemia, hypertension.It clears liver and improve vision, sharp water defaecation has laxative action, reducing blood pressure and blood fat.
Chinese yam: Korea, Japan and China are distributed in.Be used as medicine can the loss of clearing heat and detoxicating, tonifying spleen and stomach, control that the deficiency of vital energy is weak, digestion Bad, spermatorrhea, the enuresis and nameless sores or boils etc..
The effect of Radix Glycyrrhizae: having and invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.It is usually used in spleen Stomach is weak, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviates drug toxicity, strong Property.
Bitter mulberry leaf: also known as yellow wood leaf, national most area have production, the Major Foods of silkworm more.It is bitter, sweet, it is cold in nature;It dredges Dissipating wind-heat, clearing away the lungheat and moisturizing, calming the liver and improving eyesight, cooling blood and hemostasis;Suitable for control hypoglycemic, blood lipid, it is anti-inflammatory the effects of.
Sweet wormwood: having clearind deficient heat, removes hectic fever due to yin, hot summer weather is solved, the effect of preventing malaria, removing jaundice.It is usually used in warm evil impairment of yin, night heat is early It is cool, fever due to yin deficiency, hectic fever due to yin labor heat, summer-heat evil fever, malaria fever and chills, the treatment of the illnesss such as jaundice with damp-heat pathogen.
Herba Euphorbiae Humifusae: its nature and flavor is pungent flat, there is the effect of clearing heat and detoxicating, cooling blood and hemostasis, removing dampness through diuresis and removing jaundice.For dysentery, diarrhea is coughed up Blood, hematuria, hematochezia, metrorrhagia and metrostaxis, boil carbuncle swells, jaundice with damp-heat pathogen.
Embodiment of above be only preferred embodiments of the present invention will be described, not to the scope of the present invention into Row limits, and without departing from the spirit of the design of the present invention, this field ordinary engineering and technical personnel is to technical side of the invention The various changes and improvements that case is made, should fall within the scope of protection determined by the claims of the present invention.

Claims (5)

1. a kind of Chinese herbal medicine formula for treating diabetes, which is characterized in that the parts by weight of each raw material are respectively as follows: 5-8 parts of pueraria lobata, Huang 8-10 parts smart, 5-8 parts of dark plum, 8-12 parts of cassia seed, 3-5 parts of Chinese yam, 1-2 parts of Radix Glycyrrhizae, bitter 3-8 parts of mulberry leaf, 40-50 parts of sweet wormwood, 8-15 parts of Herba Euphorbiae Humifusae.
2. a kind of Chinese herbal medicine formula for treating diabetes according to claim 1, which is characterized in that the parts by weight of each raw material It is respectively as follows: 8 parts of pueraria lobata, 10 parts of rhizoma polygonati, 10 parts of dark plum, 10 parts of cassia seed, 5 parts of Chinese yam, 2 parts of Radix Glycyrrhizae, bitter 5 parts of mulberry leaf, sweet wormwood 40 Part, 10 parts of Herba Euphorbiae Humifusae.
3. a kind of preparation for the treatment of diabetes Chinese herbal medicine formula as claimed in claim 1 or 2, it is characterised in that: use existing Chinese medicine Capsule, tablet or electuary is made in the Chinese herbal medicine formula of above-mentioned treatment diabetes by preparation method.
4. a kind of preparation for treating the cooperation of diabetes Chinese herbal medicine according to claim 3, it is characterised in that: the Chinese herbal medicine Capsule, tablet or electuary made of pharmaceutically acceptable auxiliary material is added.
5. a kind of application of the Chinese herbal medicine formula for the treatment of diabetes as claimed in claim 1 or 2, it is characterised in that: the treatment sugar The Chinese herbal medicine formula for urinating disease reduces the application in hypoglycemic medicament in preparation.
CN201910619879.0A 2019-07-10 2019-07-10 A kind of Chinese herbal medicine formula that treating diabetes and its preparation and application Pending CN110279802A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1813863A (en) * 2005-12-13 2006-08-09 文镜 Functional food with blood sugar reducing action and its preparing method
CN103859378A (en) * 2012-12-10 2014-06-18 天津红日药业股份有限公司 Formula and preparation method of life cultivation and health preservation food helpful for reducing blood sugar
CN107349198A (en) * 2016-05-10 2017-11-17 复旦大学 Artemether is preparing the purposes in promoting lipolysis and improving glycometabolism preparation
CN108497383A (en) * 2018-03-30 2018-09-07 甘肃大整健康管理股份有限公司 A kind of traditional Chinese medicine health care preparation with fat-eliminating antihypelipidemic effect

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1813863A (en) * 2005-12-13 2006-08-09 文镜 Functional food with blood sugar reducing action and its preparing method
CN103859378A (en) * 2012-12-10 2014-06-18 天津红日药业股份有限公司 Formula and preparation method of life cultivation and health preservation food helpful for reducing blood sugar
CN107349198A (en) * 2016-05-10 2017-11-17 复旦大学 Artemether is preparing the purposes in promoting lipolysis and improving glycometabolism preparation
CN108497383A (en) * 2018-03-30 2018-09-07 甘肃大整健康管理股份有限公司 A kind of traditional Chinese medicine health care preparation with fat-eliminating antihypelipidemic effect

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
姜宏卫等: ""蒿甲醚在db/db小鼠中抗糖尿病及抗肥胖的作用"", 《中国中西医结合杂志》 *

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Application publication date: 20190927

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