CN110279789A - One kind is dispelled body odour activating agent and preparation method thereof - Google Patents

One kind is dispelled body odour activating agent and preparation method thereof Download PDF

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Publication number
CN110279789A
CN110279789A CN201910614579.3A CN201910614579A CN110279789A CN 110279789 A CN110279789 A CN 110279789A CN 201910614579 A CN201910614579 A CN 201910614579A CN 110279789 A CN110279789 A CN 110279789A
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phase
body odour
preparation
activating agent
raw material
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许富明
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Inorganic Chemistry (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

It dispels body odour activating agent and preparation method thereof the invention discloses one kind, required raw material includes: solvent, deodorant, emollient, moisturizer, emulsifier, skin conditioning agent, emulsion stabilizer, preservative, thickener, antioxidant, pH adjusting agent and aromatic;It is divided into A phase, B phase, C phase and D phase.The present invention is matched according to the different mechanism combination Chinese and western medical science pure sciences that body odour is formed; from raising human skin protective capability; it is selected can fragrance by the dehumidifying of dirty, relieve heat, the effective ingredients in plant of antiperspirant deodorant and its treatment body odour secret recipe; it is above-mentioned to match the ability that improve active constituent Transdermal absorption; its active constituent is firmly attached to skin surface; sustained release decomposes peculiar smell, keeps ordor removing more longlasting;And skin microecological balance is established, inhibit the bacterium for generating peculiar smell, safeguard skin beneficiating microorganism, regulates and controls skin autoimmunity, effectively anti-oxidant, reduction sweat gland secretion sebum oxidation is spoiled, securely and reliably, it has no toxic side effect, it is easy to use, it is significant in efficacy to treat body odour of dispelling.

Description

One kind is dispelled body odour activating agent and preparation method thereof
Technical field
The present invention relates to technical field of living goods, more particularly to one kind is dispelled body odour activating agent and its preparation side Method.
Background technique
Body odour is the volatile fat that generates in apocrine secretion object with the place of armpit skin apocrine sweat gland prosperity close packing Acid is decomposed a kind of a kind of unpleasant smell of stench of generation after a kind of special streptococcal infection, Xia Chongdong is light, especially the summer In season, perspiring, more, clothes is thin.Body odour has heredity, and related with sex, race's difference.In westerner, body odour is also known as " bodyodor ", means a kind of taste of body, that is, refers to body odour.About body odour, in general, women is more than male, White people and black race are more than yellow, this is mainly related with the physiological structure of apocrine sweat gland and function.Since apocrine sweat gland is in the youth Phase secretion is vigorous, therefore this disease is more common in person between twenty and fifty, with advancing age, the aging of human body, apocrine sweat gland also gradually degeneration, symptom It can mitigate or disappear.Heavier psychological burden can be therefore formed with body odour, marriage is influenced, obtains employment, enters a higher school, making friends.Very More patients therefore cause personality, thinking it is abnormal, body odour just really becomes a kind of disease-mental disease.
Cause of disease introduction: endocrine factors (35%): 1. apocrine sweat gland is influenced by endocrine, is just started secretion in puberty and is lived Jump, therefore bromhidrosis caused by apocrine sweat gland mostly occurs in puberty, can reduce or disappears to old age.2. bacterium factors (30%): due to The secretion of bacterium and apocrine sweat gland, which is had an effect, to be generated unsaturated fatty acid and leads to the formation of off-odor, and bacterium is the micro- life of protokaryon One kind of object is that a kind of shape is carefully short, the simple prokaryotes of structure.3. inherent cause (20%): such as paranoiac, schizophrenia Deng also can produce bromhidrosis.The generation of underarm odor may have relationship with heredity.
Existing Chinese traditional treatment dispel body odour method in, publication number CN104043093A(application number 201410309877.9) Patent discloses a kind of Chinese materia medica preparation of body odour of dispelling, matched by following raw material: 15-20 parts of garlic juice, folium artemisiae argyi mention Take 15-20 parts of object, 10-15 parts of alum, 10-15 parts of ginger juice, 5-10 parts of alcohol, 5-10 parts of glycerol.Publication number CN104117049A(application number 201410368229.0) patent disclose it is a kind of treat Bromhidrosis treating paste, by the original of following parts by weight Material is made: 10-20 parts of ginger, 5-15 parts of Jasmine, 7-12 parts of hops, 5-10 parts of orange peel;The system of the treatment Bromhidrosis treating paste Preparation Method includes the following steps: that (1) crushes Jasmine, hops, orange peel, and then by ginger crush, ginger juice is collected in filtering, Ginger slag is spare;(2) ginger slag, Jasmine, hops, orange peel are mixed with deionized water, is stirred evenly, then carried out at high temperature and pressure Reason, is cooled to environment temperature, obtains mixed liquor;(3) refluxing extraction three times is carried out to the mixed liquor in step (2), merging mentions three times Liquid is taken, every time in 65 °C -75 °C lower refluxing extraction 20-30min, it is 75%-95% second that 5-8 times of volume fraction is added every time Alcohol;(4) ginger juice in step (1) is mixed with extracting solution, is compressed into paste, packaging is to get treatment Bromhidrosis treating paste;The ginger The weight ratio that slag, Jasmine, hops, orange peel total weight are mixed with deionized water is 1:6-1:9;The item of the high temperature and pressure Part is 170 °C -180 °C, 0.48Mpa-0.52Mpa, and the processing time is 20-25min.Publication number CN105194397A(application number 201510684440.8) patent discloses a kind of ointment for treating body odour, and the ointment of the treatment body odour is by the following raw material system It is standby to form: sweet osmanthus, spot thatch, rose, Moschus, Jasmine, rice vinegar, mother chrysanthemum, climbing groundsel.
The method for the treatment of body odour mainly has laser therapy, operative treatment and drug therapy at present, wherein laser therapy, operation Treatment is to achieve the purpose that treatment to destroy sweat gland, and patient will bear biggish pain, undertake high Operation Fee, can destroy The normal physiological function in oxter, and a series of problems, such as postoperative complications can be generated.And drug therapy mostly uses Western medicine chemistry to close At can only play the role of temporary relief of symptoms, cannot eradicate, also easily cause skin allergy, and be easy repeatedly after being discontinued.
Therefore, how to provide it is a kind of have short treating period, it is curative for effect it is significant, have no toxic side effect, and easy to use be not easy The problem of body odour activating agent and preparation method thereof of dispelling of the features such as recurrence is those skilled in the art's urgent need to resolve.
Summary of the invention
In view of this, the present invention provides one kind have short treating period, it is curative for effect it is significant, have no toxic side effect, and use Facilitate body odour activating agent and preparation method thereof of dispelling of the features such as uneasy to recur.
To achieve the above object, the invention provides the following technical scheme:
One kind is dispelled body odour activating agent, which is characterized in that required raw material includes: solvent, deodorant, emollient, moisturizer, emulsification Agent, skin conditioning agent, emulsion stabilizer, preservative, thickener, antioxidant, pH adjusting agent and aromatic;Be divided into A phase, B phase, C phase and D phase.
Preferably, it dispels in body odour activating agent and preparation method thereof in above-mentioned one kind, the A phase includes 6% palmitinic acid second The own ester of base, 2% isononyl isononanoate, 1.8% stereth -21,1.5% dimethyl silicone polymer, 1.2% stearyl alcohol PEG-100 stearate/stearine of polyethers -2,1%, 1% cetostearyl alcohol, 0.2% tocopherol acetate, 0.05% Nipasol.
Preferably, dispel in body odour activating agent and preparation method thereof in above-mentioned one kind, the B phase include 57% water, 3% Zinc phenolsulfonate, 3% propylene glycol, 0.2% xanthan gum, 0.15% methyl hydroxybenzoate.
Preferably, dispel in body odour activating agent and preparation method thereof in above-mentioned one kind, the C phase by 15% chlorination hydroxyl aluminium, 5% Ethyl alcohol, 0.5% Phenoxyethanol, 0.1% essence, 1% aloe barbadensis Miller (ALOE BARBADENSIS) leaf extract/water.
Preferably, dispel in body odour activating agent and preparation method thereof in above-mentioned one kind, the D phase include 0.2% water, 0.1% Citric acid.
Preferably, it dispels in body odour activating agent and preparation method thereof in above-mentioned one kind, specifically includes the following steps: (1) is by A phase Raw material is added in oily phase pot, is heated to 80 DEG C, stirs evenly;(2) B phase raw material is added in vacuum emulsifying pot, is heated to It 80 DEG C, stirs 20 minutes;The oily phase pot raw material in step (1) is added, homogeneous 4 minutes, stirring after twenty minutes, started to cool down;(3) 45 DEG C are cooled to, the D phase raw material that C phase raw material is added, has dissolved in advance is uniformly mixed, continues to cool down;(4) 35 DEG C are cooled to, out Material is stood;(5) it is qualified to be examined, filling, packaging, coding;(6) qualified through sampling observation, joint sealing, storage.
It can be seen via above technical scheme that compared with prior art, the invention has the characteristics that:
(1) human skin protective capability is improved to set out, it is selected can fragrance it is effective by the dehumidifying of dirty, relieve heat, the plant of antiperspirant deodorant Ingredient and its treatment body odour secret recipe;
(2) ability of active constituent Transdermal absorption is improved, active constituent is firmly attached to skin surface, and sustained release decomposes different Taste keeps ordor removing more longlasting;
(3) skin microecological balance is established, inhibits the bacterium for generating peculiar smell, safeguards skin beneficiating microorganism, regulate and control skin itself Immunity, it is effectively anti-oxidant, it is spoiled to reduce the oxidation of sweat gland secretion sebum;
(4) medicine scientific compatibility, effective component infiltrate into affected part through skin absorption and generate drug effect, treat body odour
With remarkable result;
(5) according to Chinese medicine traditional theory, all medicine compatibilities are reasonable, and synergy is good, lasting medicine, and harmless, nontoxic Side effect, preparation is simple, and cure rate is high.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described, Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all Belong to the scope of protection of the invention.
The embodiment of the invention discloses one kind have short treating period, it is curative for effect it is significant, have no toxic side effect, and it is easy to use Body odour activating agent and preparation method thereof of dispelling of the features such as uneasy to recur.
It please refers to one kind disclosed by the invention to dispel body odour activating agent and preparation method thereof, specifically include:
Solvent, deodorant, emollient, moisturizer, emulsifier, skin conditioning agent, emulsion stabilizer, preservative, thickener, antioxygen Agent, pH adjusting agent and aromatic;It is divided into A phase, B phase, C phase and D phase.
In order to further optimize the above technical scheme, the A phase includes 6% ethylhexyl palmitate, 2% isononanoic acid Different nonyl ester, 1.8% stereth -21,1.5% dimethyl silicone polymer, 1.2% stereth -2,1% PEG- 100 stearates/stearine, 1% cetostearyl alcohol, 0.2% tocopherol acetate, 0.05% Nipasol.
In order to further optimize the above technical scheme, the B phase include 57% water, 3% zinc phenolsulfonate, 3% third Glycol, 0.2% xanthan gum, 0.15% methyl hydroxybenzoate.
In order to further optimize the above technical scheme, the C phase by 15% chlorination hydroxyl aluminium, 5% ethyl alcohol, 0.5% benzene oxygen Ethyl alcohol, 0.1% essence, 1% aloe barbadensis Miller (ALOE BARBADENSIS) leaf extract/water.
In order to further optimize the above technical scheme, the D phase includes 0.2% water, 0.1% citric acid.
In order to further optimize the above technical scheme, specifically includes the following steps: (1) A phase raw material is added in oily phase pot, 80 DEG C are heated to, is stirred evenly;(2) B phase raw material is added in vacuum emulsifying pot, is heated to 80 DEG C, stirred 20 minutes;Add Enter the oily phase pot raw material in step (1), homogeneous 4 minutes, stirring after twenty minutes, started to cool down;(3) 45 DEG C are cooled to, C phase is added Raw material, the D phase raw material dissolved in advance, are uniformly mixed, continue to cool down;(4) 35 DEG C are cooled to, is discharged, is stood;(5) through examining Qualification, filling, packaging, coding;(6) qualified through sampling observation, joint sealing, storage.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with other The difference of embodiment, the same or similar parts in each embodiment may refer to each other.For device disclosed in embodiment For, since it is corresponded to the methods disclosed in the examples, so being described relatively simple, related place is said referring to method part It is bright.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one The widest scope of cause.

Claims (6)

  1. The body odour activating agent 1. one kind is dispelled, which is characterized in that required raw material includes: solvent, deodorant, emollient, moisturizer, emulsification Agent, skin conditioning agent, emulsion stabilizer, preservative, thickener, antioxidant, pH adjusting agent and aromatic;Be divided into A phase, B phase, C phase and D phase.
  2. Body odour activating agent and preparation method 2. one kind according to claim 1 is dispelled, which is characterized in that the A phase includes 6% ethylhexyl palmitate, 2% isononyl isononanoate, 1.8% stereth -21,1.5% dimethyl silicone polymer, 1.2% stereth -2,1% PEG-100 stearate/stearine, 1% cetostearyl alcohol, 0.2% life Educate the Nipasol of phenol acetic acid esters, 0.05%.
  3. Body odour activating agent and preparation method 3. one kind according to claim 1 is dispelled, which is characterized in that the B phase includes 57% water, 3% zinc phenolsulfonate, 3% propylene glycol, 0.2% xanthan gum, 0.15% methyl hydroxybenzoate.
  4. Body odour activating agent and preparation method 4. one kind according to claim 1 is dispelled, which is characterized in that the C phase is by 15% Chlorination hydroxyl aluminium, 5% ethyl alcohol, 0.5% Phenoxyethanol, 0.1% essence, 1% aloe barbadensis Miller (ALOE BARBADENSIS) Leaf extract/water.
  5. Body odour activating agent and preparation method 5. one kind according to claim 1 is dispelled, which is characterized in that the D phase includes 0.2% water, 0.1% citric acid.
  6. 6. a kind of preparation method for body odour activating agent of dispelling, which is characterized in that specifically includes the following steps: (1) A phase raw material is added In oily phase pot, 80 DEG C are heated to, is stirred evenly;(2) B phase raw material is added in vacuum emulsifying pot, is heated to 80 DEG C, stirring 20 minutes;The oily phase pot raw material in step (1) is added, homogeneous 4 minutes, stirring after twenty minutes, started to cool down;(3) 45 are cooled to DEG C, the D phase raw material that C phase raw material is added, has dissolved in advance is uniformly mixed, continues to cool down;(4) 35 DEG C are cooled to, is discharged, is stood; (5) it is qualified to be examined, filling, packaging, coding;(6) qualified through sampling observation, joint sealing, storage.
CN201910614579.3A 2019-07-09 2019-07-09 One kind is dispelled body odour activating agent and preparation method thereof Pending CN110279789A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112089636A (en) * 2020-10-16 2020-12-18 广州博氏化妆品有限公司 Deodorizing composition and preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102300537A (en) * 2009-02-02 2011-12-28 金伯利-克拉克环球有限公司 Absorbent articles containing a multifunctional gel
CN105456176A (en) * 2015-12-29 2016-04-06 广州市科能化妆品科研有限公司 Emulsion cream and preparing method thereof
CN105473124A (en) * 2014-03-26 2016-04-06 株式会社漫丹 Deodorant composition and deodorant agent

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102300537A (en) * 2009-02-02 2011-12-28 金伯利-克拉克环球有限公司 Absorbent articles containing a multifunctional gel
CN105473124A (en) * 2014-03-26 2016-04-06 株式会社漫丹 Deodorant composition and deodorant agent
CN105456176A (en) * 2015-12-29 2016-04-06 广州市科能化妆品科研有限公司 Emulsion cream and preparing method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112089636A (en) * 2020-10-16 2020-12-18 广州博氏化妆品有限公司 Deodorizing composition and preparation method and application thereof

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Application publication date: 20190927

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